[ { "id": "Q8VCB3-1.271.271", "start_pos": 271, "end_pos": 271, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32172839", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32172839", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "CAHVFTTVSEITAIEAEHML", "down_seq": "RKPDVVTPNGLNVKKFSAVH", "snv": [ { "evidence": [ { "id": "rs32172839", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32172839" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142402027", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K271", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8VCB3-1.266.266", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.269.269", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.279.279", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388862578", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862578", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "SEITAIEAEHMLKRKPDVVT", "down_seq": "NGLNVKKFSAVHEFQNLHAM", "snv": [ { "evidence": [ { "id": "rs3388862578", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862578" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142400963", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P279", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.266.266", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.269.269", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.271.271", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32170912", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32170912", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "LSVTSLGGLPVWEAERLPVE", "down_seq": "LLLFEVSWEVTNKVGGICTV", "snv": [ { "evidence": [ { "id": "rs32170912", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32170912" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369267", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D27", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8VCB3-1.8.8", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8VCB3-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8VCB3-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8VCB3-1.43.43", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388853302", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388853302", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "M", "down_seq": "RGRSLSVTSLGGLPVWEAER", "snv": [ { "evidence": [ { "id": "rs3388853302", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388853302" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142418523", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L2", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8VCB3-1.8.8", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8VCB3-1.11.11", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.30.30", "start_pos": 30, "end_pos": 30, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388862522", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862522", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "TSLGGLPVWEAERLPVEDLL", "down_seq": "FEVSWEVTNKVGGICTVIQT", "snv": [ { "evidence": [ { "id": "rs3388862522", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862522" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142418439", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L30", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8VCB3-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8VCB3-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.27.27", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.43.43", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.405.405", "start_pos": 405, "end_pos": 405, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388830883", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388830883", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "VRKQLWDTVHCLKEKFGKKL", "down_seq": "DGLLRGEIPDMNSILDRDDL", "snv": [ { "evidence": [ { "id": "rs3388830883", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388830883" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142396210", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y405", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.413.413", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.413.413", "start_pos": 413, "end_pos": 413, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388862585", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862585", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "VHCLKEKFGKKLYDGLLRGE", "down_seq": "PDMNSILDRDDLTIMKRAIF", "snv": [ { "evidence": [ { "id": "rs3388862585", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862585" } ], "glycoeffect": [], "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142395226", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I413", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.405.405", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.431.431", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8VCB3-1.432.432", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.431.431", "start_pos": 431, "end_pos": 431, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388850613", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388850613", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "GEIPDMNSILDRDDLTIMKR", "down_seq": "IFSTQRQSLPPVTTHNMIDD", "snv": [ { "evidence": [ { "id": "rs3388850613", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388850613" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142395173", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A431", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.413.413", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8VCB3-1.432.432", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8VCB3-1.442.442", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.432.432", "start_pos": 432, "end_pos": 432, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388869034", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388869034", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "EIPDMNSILDRDDLTIMKRA", "down_seq": "FSTQRQSLPPVTTHNMIDDS", "snv": [ { "evidence": [ { "id": "rs3388869034", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388869034" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142395169", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I432", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8VCB3-1.413.413", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8VCB3-1.431.431", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.442.442", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8VCB3-1.452.452", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.43.43", "start_pos": 43, "end_pos": 43, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388868515", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388868515", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "LPVEDLLLFEVSWEVTNKVG", "down_seq": "ICTVIQTKAKTTADEWGENY", "snv": [ { "evidence": [ { "id": "rs3388868515", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388868515" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142409126", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G43", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8VCB3-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8VCB3-1.27.27", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8VCB3-1.54.54", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.56.56", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.442.442", "start_pos": 442, "end_pos": 442, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388875632", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388875632", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "RDDLTIMKRAIFSTQRQSLP", "down_seq": "VTTHNMIDDSTDPILSTIRR", "snv": [ { "evidence": [ { "id": "rs3388875632", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388875632" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142394212", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P442", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8VCB3-1.431.431", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.432.432", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.452.452", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.452.452", "start_pos": 452, "end_pos": 452, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388869020", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388869020", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IFSTQRQSLPPVTTHNMIDD", "down_seq": "TDPILSTIRRIGLFNNRADR", "snv": [ { "evidence": [ { "id": "rs3388869020", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388869020" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142394183", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S452", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8VCB3-1.432.432", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.442.442", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.465.465", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.465.465", "start_pos": 465, "end_pos": 465, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388866730", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388866730", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "THNMIDDSTDPILSTIRRIG", "down_seq": "FNNRADRVKVILHPEFLSST", "snv": [ { "evidence": [ { "id": "rs3388866730", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388866730" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142394143", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L465", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.452.452", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.479.479", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.479.479", "start_pos": 479, "end_pos": 479, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388830940", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388830940", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "TIRRIGLFNNRADRVKVILH", "down_seq": "EFLSSTSPLLPMDYEEFVRG", "snv": [ { "evidence": [ { "id": "rs3388830940", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388830940" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142391826", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P479", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.465.465", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.487.487", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VCB3-1.491.491", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.487.487", "start_pos": 487, "end_pos": 487, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388862892", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862892", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "NNRADRVKVILHPEFLSSTS", "down_seq": "LLPMDYEEFVRGCHLGVFPS", "snv": [ { "evidence": [ { "id": "rs3388862892", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862892" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142391802", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P487", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.479.479", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.491.491", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.491.491", "start_pos": 491, "end_pos": 491, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388844400", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388844400", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "M", "start_aa": "M", "up_seq": "DRVKVILHPEFLSSTSPLLP", "down_seq": "DYEEFVRGCHLGVFPSYYEP", "snv": [ { "evidence": [ { "id": "rs3388844400", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388844400" } ], "glycoeffect": [], "sequence_org": "M", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142391790", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "M491", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8VCB3-1.479.479", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.487.487", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8VCB3-1.510.510", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.538.538", "start_pos": 538, "end_pos": 538, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32174624", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32174624", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "ECTVMGIPSVTTNLSGFGCF", "down_seq": "QEHVADPTAYGIYIVDRRFR", "snv": [ { "evidence": [ { "id": "rs32174624", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32174624" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142376049", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V538", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8VCB3-1.539.539", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.540.540", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.539.539", "start_pos": 539, "end_pos": 539, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388867079", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867079", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "CTVMGIPSVTTNLSGFGCFV", "down_seq": "EHVADPTAYGIYIVDRRFRS", "snv": [ { "evidence": [ { "id": "rs3388867079", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867079" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142376047_142376048insTCTCCACACTACCTCAACCATCA", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q539", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8VCB3-1.538.538", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8VCB3-1.540.540", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.540.540", "start_pos": 540, "end_pos": 540, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388867038", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867038", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "TVMGIPSVTTNLSGFGCFVQ", "down_seq": "HVADPTAYGIYIVDRRFRSP", "snv": [ { "evidence": [ { "id": "rs3388867038", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867038" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142376042", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E540", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.538.538", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8VCB3-1.539.539", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.54.54", "start_pos": 54, "end_pos": 54, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3507845134", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3507845134", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SWEVTNKVGGICTVIQTKAK", "down_seq": "TADEWGENYFLIGPYFEHNM", "snv": [ { "evidence": [ { "id": "rs3507845134", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3507845134" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142409093", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T54", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8VCB3-1.43.43", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.56.56", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.56.56", "start_pos": 56, "end_pos": 56, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388872265", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388872265", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "EVTNKVGGICTVIQTKAKTT", "down_seq": "DEWGENYFLIGPYFEHNMKT", "snv": [ { "evidence": [ { "id": "rs3388872265", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388872265" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142409087", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A56", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.43.43", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.54.54", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.630.630", "start_pos": 630, "end_pos": 630, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs239381443", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs239381443", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HLTLSRAFPDKFHLEPTSPP", "down_seq": "TDGFKYPRPSSVPPSPSGSQ", "snv": [ { "evidence": [ { "id": "rs239381443", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs239381443" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142373081", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T630", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.631.631", "start_pos": 631, "end_pos": 631, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388867072", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867072", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LTLSRAFPDKFHLEPTSPPT", "down_seq": "DGFKYPRPSSVPPSPSGSQA", "snv": [ { "evidence": [ { "id": "rs3388867072", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388867072" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369358", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T631", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.635.635", "start_pos": 635, "end_pos": 635, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388844476", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388844476", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "RAFPDKFHLEPTSPPTTDGF", "down_seq": "YPRPSSVPPSPSGSQASSPQ", "snv": [ { "evidence": [ { "id": "rs3388844476", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388844476" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369345", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K635", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.639.639", "start_pos": 639, "end_pos": 639, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388868570", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388868570", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "DKFHLEPTSPPTTDGFKYPR", "down_seq": "SSVPPSPSGSQASSPQCSDA", "snv": [ { "evidence": [ { "id": "rs3388868570", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388868570" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369335", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P639", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.641.641", "start_pos": 641, "end_pos": 641, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388868494", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388868494", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FHLEPTSPPTTDGFKYPRPS", "down_seq": "VPPSPSGSQASSPQCSDAED", "snv": [ { "evidence": [ { "id": "rs3388868494", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388868494" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369328", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S641", "keywords": [ "ebi", "germline" ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by GSK3-alpha and GSK3-beta", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "site_lbl": "Ser641" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag", "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.643.643", "start_pos": 643, "end_pos": 643, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388875649", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388875649", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "LEPTSPPTTDGFKYPRPSSV", "down_seq": "PSPSGSQASSPQCSDAEDEE", "snv": [ { "evidence": [ { "id": "rs3388875649", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388875649" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369323", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P643", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.653.653", "start_pos": 653, "end_pos": 653, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388875672", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388875672", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GFKYPRPSSVPPSPSGSQAS", "down_seq": "PQCSDAEDEEDEDERYDEEE", "snv": [ { "evidence": [ { "id": "rs3388875672", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388875672" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369293", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S653", "keywords": [ "ebi", "germline" ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by GSK3-alpha and GSK3-beta", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "site_lbl": "Ser653" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag", "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.656.656", "start_pos": 656, "end_pos": 656, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32172034", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32172034", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "YPRPSSVPPSPSGSQASSPQ", "down_seq": "SDAEDEEDEDERYDEEEEAE", "snv": [ { "evidence": [ { "id": "rs32172034", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32172034" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369284", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C656", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.659.659", "start_pos": 659, "end_pos": 659, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs225244459", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs225244459", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "PSSVPPSPSGSQASSPQCSD", "down_seq": "EDEEDEDERYDEEEEAERDR", "snv": [ { "evidence": [ { "id": "rs225244459", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs225244459" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369274", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A659", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.661.661", "start_pos": 661, "end_pos": 661, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs32170912", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32170912", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "SVPPSPSGSQASSPQCSDAE", "down_seq": "EEDEDERYDEEEEAERDRLN", "snv": [ { "evidence": [ { "id": "rs32170912", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs32170912" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369267", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D661", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.682.682", "start_pos": 682, "end_pos": 682, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388862569", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862569", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "EEDEDERYDEEEEAERDRLN", "down_seq": "KSPFSLNHFPKGKKKLHGEY", "snv": [ { "evidence": [ { "id": "rs3388862569", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388862569" } ], "glycoeffect": [], "sequence_org": "I", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369205", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I682", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.684.684", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8VCB3-1.685.685", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.695.695", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8VCB3-1.702.702", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.685.685", "start_pos": 685, "end_pos": 685, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388853309", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388853309", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "EDERYDEEEEAERDRLNIKS", "down_seq": "FSLNHFPKGKKKLHGEYKN", "snv": [ { "evidence": [ { "id": "rs3388853309", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388853309" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369197", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P685", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.682.682", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8VCB3-1.684.684", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.695.695", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8VCB3-1.702.702", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.695.695", "start_pos": 695, "end_pos": 695, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388865618", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388865618", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "AERDRLNIKSPFSLNHFPKG", "down_seq": "KKLHGEYKN", "snv": [ { "evidence": [ { "id": "rs3388865618", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388865618" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369167", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K695", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8VCB3-1.682.682", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8VCB3-1.684.684", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.685.685", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8VCB3-1.702.702", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.702.702", "start_pos": 702, "end_pos": 702, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3397270820", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397270820", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "IKSPFSLNHFPKGKKKLHGE", "down_seq": "KN", "snv": [ { "evidence": [ { "id": "rs3397270820", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397270820" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142369146", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y702", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8VCB3-1.682.682", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.684.684", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q8VCB3-1.685.685", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8VCB3-1.695.695", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs5527846330", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527846330", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "GPYFEHNMKTQVEQCEPTND", "down_seq": "VRKAVDAMNKHGCQVHFGRW", "snv": [ { "evidence": [ { "id": "rs5527846330", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527846330" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142408995", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A87", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q8VCB3-1.92.92", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.92.92", "start_pos": 92, "end_pos": 92, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs265889866", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs265889866", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "HNMKTQVEQCEPTNDAVRKA", "down_seq": "DAMNKHGCQVHFGRWLIEGS", "snv": [ { "evidence": [ { "id": "rs265889866", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs265889866" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "142408980", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V92", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8VCB3-1.87.87", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.11.11", "start_pos": 11, "end_pos": 11, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" }, { "database": "iPTMnet", "id": "Q8VCB3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8VCB3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8VCB3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8VCB3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MLRGRSLSVT", "down_seq": "LGGLPVWEAERLPVEDLLLF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8VCB3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8VCB3" } ], "site_lbl": "Ser11" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8VCB3-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8VCB3-1.2.2", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8VCB3-1.8.8", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8VCB3-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8VCB3-1.27.27", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8VCB3-1.30.30", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VCB3-1.627.627", "start_pos": 627, "end_pos": 627, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HARHLTLSRAFPDKFHLEPT", "down_seq": "PPTTDGFKYPRPSSVPPSPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "site_lbl": "Ser627" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.645.645", "start_pos": 645, "end_pos": 645, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTSPPTTDGFKYPRPSSVPP", "down_seq": "PSGSQASSPQCSDAEDEEDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by GSK3-alpha and GSK3-beta", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "site_lbl": "Ser645" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.627.627", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.649.649", "start_pos": 649, "end_pos": 649, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTTDGFKYPRPSSVPPSPSG", "down_seq": "QASSPQCSDAEDEEDEDERY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by GSK3-alpha and GSK3-beta", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "site_lbl": "Ser649" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8VCB3-1.630.630", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.631.631", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.635.635", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VCB3-1.657.657", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.657.657", "start_pos": 657, "end_pos": 657, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRPSSVPPSPSGSQASSPQC", "down_seq": "DAEDEEDEDERYDEEEEAER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CK2", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "site_lbl": "Ser657" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8VCB3-1.639.639", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8VCB3-1.641.641", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8VCB3-1.643.643", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8VCB3-1.645.645", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VCB3-1.649.649", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8VCB3-1.653.653", "categories": [ "snv_flag", "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8VCB3-1.656.656", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8VCB3-1.659.659", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8VCB3-1.661.661", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VCB3-1.684.684", "start_pos": 684, "end_pos": 684, "uniprot_canonical_ac": "Q8VCB3-1", "length": 704, "uniprot_id": "GYS2_MOUSE", "protein_name": "Glycogen [starch] synthase, liver", "refseq_ac": "NP_663547", "refseq_name": "glycogen [starch] synthase, liver isoform 1", "gene_name": "Gys2", "gene_names_uniprotkb": "Gys2", "gene_names_refseq": "Gys2; LGS", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" }, { "database": "iPTMnet", "id": "Q8VCB3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8VCB3" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8VCB3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8VCB3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DEDERYDEEEEAERDRLNIK", "down_seq": "PFSLNHFPKGKKKLHGEYKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8VCB3", "url": "https://www.uniprot.org/uniprotkb/Q8VCB3" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q8VCB3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8VCB3" } ], "site_lbl": "Ser684" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "8", "end_pos": "8" } ] }, { "type": "snv", "site_list": [ { "start_pos": "133", "end_pos": "133" }, { "start_pos": "167", "end_pos": "167" }, { "start_pos": "179", "end_pos": "179" }, { "start_pos": "204", "end_pos": "204" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "269", "end_pos": "269" }, { "start_pos": "271", "end_pos": "271" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "405", "end_pos": "405" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "431", "end_pos": "431" }, { "start_pos": "432", "end_pos": "432" }, { "start_pos": "43", "end_pos": "43" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "487", "end_pos": "487" }, { "start_pos": "491", "end_pos": "491" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "539", "end_pos": "539" }, { "start_pos": "540", "end_pos": "540" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "56", "end_pos": "56" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "631", "end_pos": "631" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "656", "end_pos": "656" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "682", "end_pos": "682" }, { "start_pos": "685", "end_pos": "685" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "92", "end_pos": "92" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "627", "end_pos": "627" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "645", "end_pos": "645" }, { "start_pos": "649", "end_pos": "649" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "657", "end_pos": "657" }, { "start_pos": "684", "end_pos": "684" }, { "start_pos": "8", "end_pos": "8" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8VCB3-1.682.682", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8VCB3-1.685.685", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8VCB3-1.695.695", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VCB3-1.702.702", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q4VBD9-1.160.160", "start_pos": 160, "end_pos": 160, "uniprot_canonical_ac": "Q4VBD9-1", "length": 706, "uniprot_id": "GZF1_MOUSE", "protein_name": "GDNF-inducible zinc finger protein 1", "refseq_ac": "NP_083262", "refseq_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "gene_names_uniprotkb": "Gzf1; Zfp336", "gene_names_refseq": "8430437G08Rik; Gzf1; Zfp336; mGZF1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LQNFSESQEVEASSGPQVSV", "down_seq": "PSSKASVPGEDAHSNGLVDS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr160", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "160", "end_pos": "160" } ] }, { "type": "snv", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "648", "end_pos": "648" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "611", "end_pos": "611" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "Q4VBD9-1.179.179", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q4VBD9-1.179.179", "start_pos": 179, "end_pos": 179, "uniprot_canonical_ac": "Q4VBD9-1", "length": 706, "uniprot_id": "GZF1_MOUSE", "protein_name": "GDNF-inducible zinc finger protein 1", "refseq_ac": "NP_083262", "refseq_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "gene_names_uniprotkb": "Gzf1; Zfp336", "gene_names_refseq": "8430437G08Rik; Gzf1; Zfp336; mGZF1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388586027", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388586027", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "VTPSSKASVPGEDAHSNGLV", "down_seq": "SSDYPIERLGNGLSPETPSK", "snv": [ { "evidence": [ { "id": "rs3388586027", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388586027" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DSS->NSS).", "chr_id": "2", "chr_pos": "148526065", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D179", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "160", "end_pos": "160" } ] }, { "type": "snv", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "648", "end_pos": "648" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "611", "end_pos": "611" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q4VBD9-1.160.160", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q4VBD9-1.648.648", "start_pos": 648, "end_pos": 648, "uniprot_canonical_ac": "Q4VBD9-1", "length": 706, "uniprot_id": "GZF1_MOUSE", "protein_name": "GDNF-inducible zinc finger protein 1", "refseq_ac": "NP_083262", "refseq_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "gene_names_uniprotkb": "Gzf1; Zfp336", "gene_names_refseq": "8430437G08Rik; Gzf1; Zfp336; mGZF1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388596541", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388596541", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "ASPKLSDRLLSFGENSHFNN", "down_seq": "LEVQGNVPAVQENSSTGAAC", "snv": [ { "evidence": [ { "id": "rs3388596541", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388596541" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "L", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NNL->NNS).", "chr_id": "2", "chr_pos": "148532790", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L648", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "160", "end_pos": "160" } ] }, { "type": "snv", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "648", "end_pos": "648" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "611", "end_pos": "611" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q4VBD9-1.611.611", "start_pos": 611, "end_pos": 611, "uniprot_canonical_ac": "Q4VBD9-1", "length": 706, "uniprot_id": "GZF1_MOUSE", "protein_name": "GDNF-inducible zinc finger protein 1", "refseq_ac": "NP_083262", "refseq_name": "GDNF-inducible zinc finger protein 1", "gene_name": "Gzf1", "gene_names_uniprotkb": "Gzf1; Zfp336", "gene_names_refseq": "8430437G08Rik; Gzf1; Zfp336; mGZF1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9" }, { "database": "iPTMnet", "id": "Q4VBD9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q4VBD9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q4VBD9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q4VBD9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HTSIHDKNTPWKSFLVIVDG", "down_seq": "PKNDEGHKTEQPDDEYASPK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q4VBD9", "url": "https://www.uniprot.org/uniprotkb/Q4VBD9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q4VBD9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q4VBD9" } ], "site_lbl": "Ser611" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "160", "end_pos": "160" } ] }, { "type": "snv", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "648", "end_pos": "648" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "611", "end_pos": "611" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "G3X972-1.592.592", "start_pos": 592, "end_pos": 592, "uniprot_canonical_ac": "G3X972-1", "length": 1096, "uniprot_id": "G3X972_MOUSE", "protein_name": "SEC24 homolog C, COPII coat complex component", "refseq_ac": "NP_766184", "refseq_name": "protein transport protein Sec24C isoform 1", "gene_name": "Sec24c", "gene_names_uniprotkb": "Sec24c", "gene_names_refseq": "2610204K03Rik; Sec24c; mKIAA0079", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "G3X972", "url": "https://www.uniprot.org/uniprotkb/G3X972" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MMVVSDVADMFVPLLDGFLV", "down_seq": "VSESRAVITSLLDQIPEMFA", "glycosylation": [ { "glytoucan_ac": "G05722ES", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SSLAQPQMMVVSDVADMFVPLLDGFLVNVSESR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn592", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "G3X972-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "G3X972-1", "length": 1096, "uniprot_id": "G3X972_MOUSE", "protein_name": "SEC24 homolog C, COPII coat complex component", "refseq_ac": "NP_766184", "refseq_name": "protein transport protein Sec24C isoform 1", "gene_name": "Sec24c", "gene_names_uniprotkb": "Sec24c", "gene_names_refseq": "2610204K03Rik; Sec24c; mKIAA0079", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "G3X972", "url": "https://www.uniprot.org/uniprotkb/G3X972" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "G3X972", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "G3X972", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "G3X972", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "G3X972", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "G3X972", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "G3X972", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "G3X972", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=G3X972" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "592", "end_pos": "592" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17182-1.102.102", "start_pos": 102, "end_pos": 102, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VNVVEQEKIDKLMIEMDGTE", "down_seq": "KSKFGANAILGVSLAVCKAG", "glycosylation": [ { "glytoucan_ac": "G93067EQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VNVVEQEKIDKLMIEMDGTENK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn102", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17182-1.70.70", "start_pos": 70, "end_pos": 70, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3553646168", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3553646168", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs3553627339", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3553627339", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RDNDKTRFMGKGVSQAVEHI", "down_seq": "KTIAPALVSKKVNVVEQEKI", "glycosylation": [ { "glytoucan_ac": "G12745LE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "FMGKGVSQAVEHINKTIAPALVSK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3553646168", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3553646168" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NKT->HKT).", "chr_id": "18", "chr_pos": "48180031", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N70", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs3553627339", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3553627339" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NKT->SKT).", "chr_id": "18", "chr_pos": "48180032", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N70", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17182-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease.", "journal": "Biochimica et biophysica acta. Molecular basis of disease", "date": "2018", "authors": "Tramutola A, Sharma N, Barone E, Lanzillotta C, Castellani A, Iavarone F, Vincenzoni F, Castagnola M, Butterfield DA, Gaetani S, Cassano T, Perluigi M, Di Domenico F", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" } ], "reference": [ { "type": "PubMed", "id": "30031227", "url": "https://glygen.org/publication/PubMed/30031227" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17182", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30031227", "url": "https://glygen.org/publication/PubMed/30031227", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P17182", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17182" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "30031227", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30031227" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17182-1.254.254", "start_pos": 254, "end_pos": 254, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGYTDQVVIGMDVAASEFYR", "down_seq": "GKYDLDFKSPDDPSRYITPD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "site_lbl": "Ser254" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "P17182-1.263.263", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17182-1.263.263", "start_pos": 263, "end_pos": 263, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" }, { "database": "iPTMnet", "id": "P17182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17182" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17182", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GMDVAASEFYRSGKYDLDFK", "down_seq": "PDDPSRYITPDQLADLYKSF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P17182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17182" } ], "site_lbl": "Ser263" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "P17182-1.254.254", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17182-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PSRYITPDQLADLYKSFVQN", "down_seq": "PVVSIEDPFDQDDWGAWQKF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "site_lbl": "Tyr287" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P17182-1.291.291", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17182-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ITPDQLADLYKSFVQNYPVV", "down_seq": "IEDPFDQDDWGAWQKFTASA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "site_lbl": "Ser291" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P17182-1.287.287", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17182-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "P17182-1", "length": 434, "uniprot_id": "ENOA_MOUSE", "protein_name": "Alpha-enolase", "refseq_ac": "NP_001020559", "refseq_name": "enolase 1B, retrotransposed", "gene_name": "Eno1", "gene_names_uniprotkb": "Eno1; Eno-1", "gene_names_refseq": "EG433182; Eno-1; Eno1b; Eno1; Gm5506; NNE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" }, { "database": "iPTMnet", "id": "P17182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17182" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] } ], "crossref": [ { "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17182", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LYTAKGLFRAAVPSGASTGI", "down_seq": "EALELRDNDKTRFMGKGVSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P17182", "url": "https://www.uniprot.org/uniprotkb/P17182" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "P17182", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17182" } ], "site_lbl": "Tyr44" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "70", "end_pos": "70" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "254", "end_pos": "254" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9PYH6-1.1320.1320", "start_pos": 1320, "end_pos": 1320, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LLSHILLEHNYALAIKPPPT", "down_seq": "PAPRPLEPAPALAALFSSPA", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1320", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.236.236", "start_pos": 236, "end_pos": 236, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ARRRSSSDTAAYPAGTTVGG", "down_seq": "PGNGTPCSQDTNFSSSRQDT", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr236", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.278.278", "start_pos": 278, "end_pos": 278, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9PYH6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9PYH6" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9PYH6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9PYH6" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9PYH6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9PYH6" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9PYH6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9PYH6" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "E9PYH6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9PYH6", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "rs3388950355", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388950355", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSFGQFTPQSSQGTPYTSRG", "down_seq": "TPYSQDSAYSSSTTSTSFKP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser278", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "E9PYH6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9PYH6" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388950355", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388950355" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (S->C).", "chr_id": "7", "chr_pos": "127383337", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S278", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9PYH6-1.612.612", "start_pos": 612, "end_pos": 612, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SGEDMEISDDDRGGSPPPAP", "down_seq": "PPQQPPPPPPPPPPPPPPYL", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.931.931", "start_pos": 931, "end_pos": 931, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KRKEPSEISEASEEKRPRPS", "down_seq": "PAEEDEDDPEREKEAGEPGR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr931", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "E9PYH6-1.930.930", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.1702.1702", "start_pos": 1702, "end_pos": 1702, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388945646", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388945646", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "PIGVDEEITYDYKFPLEDNK", "down_seq": "PCLCGTESCRGSLN", "snv": [ { "evidence": [ { "id": "rs3388945646", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388945646" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NKI->NKS).", "chr_id": "7", "chr_pos": "127398605", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I1702", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.1110.1110", "start_pos": 1110, "end_pos": 1110, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EVPEPLPAPDEKPETDGLVD", "down_seq": "PVMPLSEKETLPTQPAGPAE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "site_lbl": "Ser1110" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.477.477", "start_pos": 477, "end_pos": 477, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGGGAPSPEREEARTPPRPA", "down_seq": "PARSGSPAPETTNESVPFAQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "site_lbl": "Ser477" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.521.521", "start_pos": 521, "end_pos": 521, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDSRIEMLLKEQRSKFSFLA", "down_seq": "DTEEEEENSSAGPGARDAGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "site_lbl": "Ser521" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.578.578", "start_pos": 578, "end_pos": 578, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PANFEDVAPTGSGEPGAARE", "down_seq": "PKANGQNQASPCSSGEDMEI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "site_lbl": "Ser578" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9PYH6-1.930.930", "start_pos": 930, "end_pos": 930, "uniprot_canonical_ac": "E9PYH6-1", "length": 1716, "uniprot_id": "SET1A_MOUSE", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "refseq_ac": "NP_821172", "refseq_name": "histone-lysine N-methyltransferase SETD1A", "gene_name": "Setd1a", "gene_names_uniprotkb": "Setd1a", "gene_names_refseq": "KMT2F; Nsccn1; Setd1a; mKIAA0339; mNSC1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKRKEPSEISEASEEKRPRP", "down_seq": "TPAEEDEDDPEREKEAGEPG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E9PYH6", "url": "https://www.uniprot.org/uniprotkb/E9PYH6" } ], "site_lbl": "Ser930" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1320", "end_pos": "1320" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "612", "end_pos": "612" }, { "start_pos": "931", "end_pos": "931" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1702", "end_pos": "1702" }, { "start_pos": "278", "end_pos": "278" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1110", "end_pos": "1110" }, { "start_pos": "477", "end_pos": "477" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "578", "end_pos": "578" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "E9PYH6-1.931.931", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q1A5-1.329.329", "start_pos": 329, "end_pos": 329, "uniprot_canonical_ac": "E9Q1A5-1", "length": 584, "uniprot_id": "E9Q1A5_MOUSE", "protein_name": "Zinc finger protein 384", "refseq_ac": "NP_780766", "refseq_name": "zinc finger protein 384 isoform 1", "gene_name": "Zfp384", "gene_names_uniprotkb": "Zfp384", "gene_names_refseq": "C130073D16Rik; Ciz; NP; Nmp4; Zfp384", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q1A5", "url": "https://www.uniprot.org/uniprotkb/E9Q1A5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3388860930", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388860930", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KMHTETIKPHKCPHCSKTFA", "down_seq": "TSYLAQHLRIHSGAKPYNCS", "glycosylation": [ { "glytoucan_ac": "G85269DF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TFANTSYLAQHLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn329", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388860930", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388860930" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NTS->YTS).", "chr_id": "6", "chr_pos": "125008704", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N329", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "329", "end_pos": "329" } ] }, { "type": "snv", "site_list": [ { "start_pos": "329", "end_pos": "329" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "upstream", "id": "E9Q1A5-1.339.339", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q1A5-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "E9Q1A5-1", "length": 584, "uniprot_id": "E9Q1A5_MOUSE", "protein_name": "Zinc finger protein 384", "refseq_ac": "NP_780766", "refseq_name": "zinc finger protein 384 isoform 1", "gene_name": "Zfp384", "gene_names_uniprotkb": "Zfp384", "gene_names_refseq": "C130073D16Rik; Ciz; NP; Nmp4; Zfp384", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q1A5", "url": "https://www.uniprot.org/uniprotkb/E9Q1A5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9Q1A5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q1A5" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9Q1A5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q1A5" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "E9Q1A5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q1A5", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "E9Q1A5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q1A5" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "329", "end_pos": "329" } ] }, { "type": "snv", "site_list": [ { "start_pos": "329", "end_pos": "329" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q1A5-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "E9Q1A5-1", "length": 584, "uniprot_id": "E9Q1A5_MOUSE", "protein_name": "Zinc finger protein 384", "refseq_ac": "NP_780766", "refseq_name": "zinc finger protein 384 isoform 1", "gene_name": "Zfp384", "gene_names_uniprotkb": "Zfp384", "gene_names_refseq": "C130073D16Rik; Ciz; NP; Nmp4; Zfp384", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q1A5", "url": "https://www.uniprot.org/uniprotkb/E9Q1A5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388845402", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388845402", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "KCPHCSKTFANTSYLAQHLR", "down_seq": "HSGAKPYNCSYCQKAFRQLS", "snv": [ { "evidence": [ { "id": "rs3388845402", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388845402" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (IHS->NHS).", "chr_id": "6", "chr_pos": "125008735", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I339", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "329", "end_pos": "329" } ] }, { "type": "snv", "site_list": [ { "start_pos": "329", "end_pos": "329" }, { "start_pos": "339", "end_pos": "339" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "E9Q1A5-1.329.329", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9JIM3-1.968.968", "start_pos": 968, "end_pos": 968, "uniprot_canonical_ac": "Q9JIM3-1", "length": 1537, "uniprot_id": "ER6L2_MOUSE", "protein_name": "DNA excision repair protein ERCC-6-like 2", "refseq_ac": "NP_001013626", "refseq_name": "DNA excision repair protein ERCC-6-like 2 isoform 1", "gene_name": "Ercc6l2", "gene_names_uniprotkb": "Ercc6l2; 0610007P08Rik; Rad26l", "gene_names_refseq": "0610007P08Rik; 1700019D06Rik; 9330134C04Rik; Ercc6l2; Rad26l; Sr278", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3" }, { "database": "iPTMnet", "id": "Q9JIM3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9JIM3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9JIM3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9JIM3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LCLENMTSKSVRKRKGTDDI", "down_seq": "DESDDIDMFPKSRIRKQRAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9JIM3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9JIM3" } ], "site_lbl": "Ser968" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "968", "end_pos": "968" }, { "start_pos": "971", "end_pos": "971" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q9JIM3-1.971.971", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9JIM3-1.971.971", "start_pos": 971, "end_pos": 971, "uniprot_canonical_ac": "Q9JIM3-1", "length": 1537, "uniprot_id": "ER6L2_MOUSE", "protein_name": "DNA excision repair protein ERCC-6-like 2", "refseq_ac": "NP_001013626", "refseq_name": "DNA excision repair protein ERCC-6-like 2 isoform 1", "gene_name": "Ercc6l2", "gene_names_uniprotkb": "Ercc6l2; 0610007P08Rik; Rad26l", "gene_names_refseq": "0610007P08Rik; 1700019D06Rik; 9330134C04Rik; Ercc6l2; Rad26l; Sr278", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3" }, { "database": "iPTMnet", "id": "Q9JIM3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9JIM3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9JIM3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9JIM3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ENMTSKSVRKRKGTDDISDE", "down_seq": "DDIDMFPKSRIRKQRATTSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9JIM3", "url": "https://www.uniprot.org/uniprotkb/Q9JIM3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9JIM3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9JIM3" } ], "site_lbl": "Ser971" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "968", "end_pos": "968" }, { "start_pos": "971", "end_pos": "971" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9JIM3-1.968.968", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z1S3-1.271.271", "start_pos": 271, "end_pos": 271, "uniprot_canonical_ac": "Q9Z1S3-1", "length": 795, "uniprot_id": "GRP1_MOUSE", "protein_name": "RAS guanyl-releasing protein 1", "refseq_ac": "NP_035376", "refseq_name": "RAS guanyl-releasing protein 1", "gene_name": "Rasgrp1", "gene_names_uniprotkb": "Rasgrp1; Rasgrp", "gene_names_refseq": "Rasgrp1; Rasgrp; calDAG-GEFII", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "RasGRP1 sensitizes an immature B cell line to antigen receptor-induced apoptosis.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Guilbault B, Kay RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" } ], "reference": [ { "type": "PubMed", "id": "14970203", "url": "https://glygen.org/publication/PubMed/14970203" } ] }, { "title": "Regulation of RasGRP via a phorbol ester-responsive C1 domain.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Tognon CE, Kirk HE, Passmore LA, Whitehead IP, Der CJ, Kay RJ", "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" } ], "reference": [ { "type": "PubMed", "id": "9819387", "url": "https://glygen.org/publication/PubMed/9819387" } ] } ], "crossref": [ { "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "14970203", "url": "https://glygen.org/publication/PubMed/14970203", "database": "PubMed", "categories": [ "Other" ] }, { "id": "9819387", "url": "https://glygen.org/publication/PubMed/9819387", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "CNGISQWVQLMVLSRPTPQL", "down_seq": "AEVFIKFIHVAQKLHQLQNF", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Loss of function and transforming activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" }, { "database": "PubMed", "id": "14970203", "url": "https://glygen.org/publication/PubMed/14970203" }, { "database": "PubMed", "id": "9819387", "url": "https://glygen.org/publication/PubMed/9819387" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "271", "end_pos": "271" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "597", "end_pos": "597" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z1S3-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "Q9Z1S3-1", "length": 795, "uniprot_id": "GRP1_MOUSE", "protein_name": "RAS guanyl-releasing protein 1", "refseq_ac": "NP_035376", "refseq_name": "RAS guanyl-releasing protein 1", "gene_name": "Rasgrp1", "gene_names_uniprotkb": "Rasgrp1; Rasgrp", "gene_names_refseq": "Rasgrp1; Rasgrp; calDAG-GEFII", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis.", "journal": "Leukemia", "date": "2012", "authors": "Oki T, Kitaura J, Watanabe-Okochi N, Nishimura K, Maehara A, Uchida T, Komeno Y, Nakahara F, Harada Y, Sonoki T, Harada H, Kitamura T", "evidence": [ { "database": "iPTMnet", "id": "Q9Z1S3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z1S3" } ], "reference": [ { "type": "PubMed", "id": "22116551", "url": "https://glygen.org/publication/PubMed/22116551" } ] } ], "crossref": [ { "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Z1S3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z1S3", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "22116551", "url": "https://glygen.org/publication/PubMed/22116551", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "THCHLIDTTQINSRDWSRKL", "down_seq": "QRIKSNTSKKRKVSLLFDHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PKC", "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" }, { "database": "iPTMnet", "id": "Q9Z1S3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9Z1S3" }, { "database": "PubMed", "id": "22116551", "url": "https://glygen.org/publication/PubMed/22116551" } ], "site_lbl": "Thr184" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "271", "end_pos": "271" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "597", "end_pos": "597" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9Z1S3-1.597.597", "start_pos": 597, "end_pos": 597, "uniprot_canonical_ac": "Q9Z1S3-1", "length": 795, "uniprot_id": "GRP1_MOUSE", "protein_name": "RAS guanyl-releasing protein 1", "refseq_ac": "NP_035376", "refseq_name": "RAS guanyl-releasing protein 1", "gene_name": "Rasgrp1", "gene_names_uniprotkb": "Rasgrp1; Rasgrp", "gene_names_refseq": "Rasgrp1; Rasgrp; calDAG-GEFII", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MNCHKQCKDLVVFECKKRIK", "down_seq": "PAISTENISSVVPMSTLCPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9Z1S3", "url": "https://www.uniprot.org/uniprotkb/Q9Z1S3" } ], "site_lbl": "Ser597" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "271", "end_pos": "271" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "184", "end_pos": "184" }, { "start_pos": "597", "end_pos": "597" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.73.73", "start_pos": 73, "end_pos": 73, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NAGAVIGKGGKNIKALRTDY", "down_seq": "ASVSVPDSSGPERILSISAD", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ALRTDYNASVSVPDSSGPER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn73", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G11314AS", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MQYNASVSVPDSSGPER", "relation": "attached", "comment": "reported site N4 is on non-canonical isoform H3BJS9-1 which maps to canonical isoform site P61979-1:73", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn73", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P61979-1.75.75", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P61979-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P61979", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P61979" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P61979", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P61979" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P61979", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P61979" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P61979", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P61979", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P61979", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P61979" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P61979-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TIGEILKKIIPTLEEGLQLP", "down_seq": "PTATSQLPLESDAVECLNYQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "site_lbl": "Ser116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P61979-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LIGGKPDRVVECIKIILDLI", "down_seq": "ESPIKGRAQPYDPNFYDETY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Ser214" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P61979-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] } ], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGKPDRVVECIKIILDLISE", "down_seq": "PIKGRAQPYDPNFYDETYDY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "site_lbl": "Ser216" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P61979-1.214.214", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P61979-1.284.284", "start_pos": 284, "end_pos": 284, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPPGRGGRPMPPSRRDYDDM", "down_seq": "PRRGPPPPPPGRGGRGGSRA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Ser284" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "P61979-1.302.302", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.302.302", "start_pos": 302, "end_pos": 302, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "PKCdelta regulates the stimulation of vascular endothelial factor mRNA translation by angiotensin II through hnRNP K.", "journal": "Cellular signalling", "date": "2008", "authors": "Sataranatarajan K, Lee MJ, Mariappan MM, Feliers D", "evidence": [ { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "reference": [ { "type": "PubMed", "id": "18295448", "url": "https://glygen.org/publication/PubMed/18295448" } ] } ], "crossref": [ { "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "18295448", "url": "https://glygen.org/publication/PubMed/18295448", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DMSPRRGPPPPPPGRGGRGG", "down_seq": "RARNLPLPPPPPPRGGDLMA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" }, { "database": "PubMed", "id": "18295448", "url": "https://glygen.org/publication/PubMed/18295448" } ], "site_lbl": "Ser302" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P61979-1.284.284", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P61979-1.36.36", "start_pos": 36, "end_pos": 36, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGEFGKRPAEDMEEEQAFKR", "down_seq": "RNTDEMVELRILLQSKNAGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Ser36" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P61979-1.39.39", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.379.379", "start_pos": 379, "end_pos": 379, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MAYEPQGGSGYDYSYAGGRG", "down_seq": "YGDLGGPIITTQVTIPKDLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Ser379" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P61979-1.380.380", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.380.380", "start_pos": 380, "end_pos": 380, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "AYEPQGGSGYDYSYAGGRGS", "down_seq": "GDLGGPIITTQVTIPKDLAG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Tyr380" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P61979-1.379.379", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.39.39", "start_pos": 39, "end_pos": 39, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FGKRPAEDMEEEQAFKRSRN", "down_seq": "DEMVELRILLQSKNAGAVIG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P61979", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P61979" } ], "site_lbl": "Thr39" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P61979-1.36.36", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P61979-1.420.420", "start_pos": 420, "end_pos": 420, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSIIGKGGQRIKQIRHESGA", "down_seq": "IKIDEPLEGSEDRIITITGT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Ser420" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P61979-1.75.75", "start_pos": 75, "end_pos": 75, "uniprot_canonical_ac": "P61979-1", "length": 463, "uniprot_id": "HNRPK_MOUSE", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "refseq_ac": "NP_001288269", "refseq_name": "heterogeneous nuclear ribonucleoprotein K isoform 1", "gene_name": "Hnrnpk", "gene_names_uniprotkb": "Hnrnpk; Hnrpk", "gene_names_refseq": "Hnrnpk; Hnrpk; KBBP; NOVA", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GAVIGKGGKNIKALRTDYNA", "down_seq": "VSVPDSSGPERILSISADIE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P61979", "url": "https://www.uniprot.org/uniprotkb/P61979" } ], "site_lbl": "Ser75" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "73", "end_pos": "73" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "302", "end_pos": "302" }, { "start_pos": "36", "end_pos": "36" }, { "start_pos": "379", "end_pos": "379" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "75", "end_pos": "75" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P61979-1.73.73", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80XP8-1.148.148", "start_pos": 148, "end_pos": 148, "uniprot_canonical_ac": "Q80XP8-1", "length": 339, "uniprot_id": "FA76B_MOUSE", "protein_name": "Protein FAM76B", "refseq_ac": "NP_789806", "refseq_name": "protein FAM76B isoform 1", "gene_name": "Fam76b", "gene_names_uniprotkb": "Fam76b", "gene_names_refseq": "2810485I05Rik; Fam76b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CWLCTLSYKRVLQKTKEQRK", "down_seq": "LGSSHSNSSSSSLTEKDQHH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" } ], "site_lbl": "Ser148" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "148", "end_pos": "148" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "22", "end_pos": "22" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80XP8-1.193.193", "start_pos": 193, "end_pos": 193, "uniprot_canonical_ac": "Q80XP8-1", "length": 339, "uniprot_id": "FA76B_MOUSE", "protein_name": "Protein FAM76B", "refseq_ac": "NP_789806", "refseq_name": "protein FAM76B isoform 1", "gene_name": "Fam76b", "gene_names_uniprotkb": "Fam76b", "gene_names_refseq": "2810485I05Rik; Fam76b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" }, { "database": "iPTMnet", "id": "Q80XP8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80XP8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80XP8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80XP8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HHHHHHHHRHSSGHHKVSSL", "down_seq": "PEQEQGLWKQSHKSSAAIQN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80XP8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80XP8" } ], "site_lbl": "Ser193" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "148", "end_pos": "148" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "22", "end_pos": "22" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80XP8-1.215.215", "start_pos": 215, "end_pos": 215, "uniprot_canonical_ac": "Q80XP8-1", "length": 339, "uniprot_id": "FA76B_MOUSE", "protein_name": "Protein FAM76B", "refseq_ac": "NP_789806", "refseq_name": "protein FAM76B isoform 1", "gene_name": "Fam76b", "gene_names_uniprotkb": "Fam76b", "gene_names_refseq": "2810485I05Rik; Fam76b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" }, { "database": "iPTMnet", "id": "Q80XP8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80XP8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80XP8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80XP8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EQEQGLWKQSHKSSAAIQNE", "down_seq": "PKKKPKLESKPSNGDSSSIN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80XP8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80XP8" } ], "site_lbl": "Thr215" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "148", "end_pos": "148" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "22", "end_pos": "22" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80XP8-1.22.22", "start_pos": 22, "end_pos": 22, "uniprot_canonical_ac": "Q80XP8-1", "length": 339, "uniprot_id": "FA76B_MOUSE", "protein_name": "Protein FAM76B", "refseq_ac": "NP_789806", "refseq_name": "protein FAM76B isoform 1", "gene_name": "Fam76b", "gene_names_uniprotkb": "Fam76b", "gene_names_refseq": "2810485I05Rik; Fam76b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AASALYACTKCTQRYPFEEL", "down_seq": "QGQQLCKECRIAHPIVKCTY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80XP8", "url": "https://www.uniprot.org/uniprotkb/Q80XP8" } ], "site_lbl": "Ser22" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "148", "end_pos": "148" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "22", "end_pos": "22" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.2627.2627", "start_pos": 2627, "end_pos": 2627, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PLREEEWDEEEEEESDVPAP", "down_seq": "SPPVSPVNSRKHRAGVDIHS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2627", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.2847.2847", "start_pos": 2847, "end_pos": 2847, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EFSASVIQMCGVMLSGSEES", "down_seq": "PSIIYHCALRGLERLLLSEQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2847", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.2922.2922", "start_pos": 2922, "end_pos": 2922, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "CMYTGKEKASPGRASDPSPA", "down_seq": "PDSESVIVAMERVSVLFDRI", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2922", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P42859", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P42859" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P42859", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P42859", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "P42859", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P42859" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P42859-1.1159.1159", "start_pos": 1159, "end_pos": 1159, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTPGPAIKAALPSLTNPPSL", "down_seq": "PIRRKGKEKEPGEQASTPMS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDK5", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "site_lbl": "Ser1159" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "P42859-1.1179.1179", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.1179.1179", "start_pos": 1179, "end_pos": 1179, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPIRRKGKEKEPGEQASTPM", "down_seq": "PKKVGEASAASRQSDTSGPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDK5", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "site_lbl": "Ser1179" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P42859-1.1159.1159", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.1853.1853", "start_pos": 1853, "end_pos": 1853, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VQQTPKRHSLSCTKSLNPQK", "down_seq": "GEEEDSGSAAQLGMCNREIV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "site_lbl": "Ser1853" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P42859-1.396.396", "start_pos": 396, "end_pos": 396, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TPGGLGQLTLVQEEARGRGR", "down_seq": "GSIVELLAGGGSSCSPVLSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "site_lbl": "Ser396" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P42859-1.398.398", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P42859-1.411.411", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P42859-1.398.398", "start_pos": 398, "end_pos": 398, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGLGQLTLVQEEARGRGRSG", "down_seq": "IVELLAGGGSSCSPVLSRKQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "site_lbl": "Ser398" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P42859-1.396.396", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P42859-1.411.411", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P42859-1.411.411", "start_pos": 411, "end_pos": 411, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RGRGRSGSIVELLAGGGSSC", "down_seq": "PVLSRKQKGKVLLGEEEALE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P42859", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P42859" } ], "site_lbl": "Ser411" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P42859-1.396.396", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P42859-1.398.398", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P42859-1.620.620", "start_pos": 620, "end_pos": 620, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSLALQQAHLLERMGHSRQP", "down_seq": "DSSIDKYVTRDEVAEASDPE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "site_lbl": "Ser620" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P42859-1.623.623", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P42859-1.623.623", "start_pos": 623, "end_pos": 623, "uniprot_canonical_ac": "P42859-1", "length": 3119, "uniprot_id": "HD_MOUSE", "protein_name": "Huntingtin", "refseq_ac": "", "refseq_name": "", "gene_name": "Htt", "gene_names_uniprotkb": "Htt; Hdh; Hd", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALQQAHLLERMGHSRQPSDS", "down_seq": "IDKYVTRDEVAEASDPESKP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P42859", "url": "https://www.uniprot.org/uniprotkb/P42859" } ], "site_lbl": "Ser623" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2627", "end_pos": "2627" }, { "start_pos": "2847", "end_pos": "2847" }, { "start_pos": "2922", "end_pos": "2922" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1159", "end_pos": "1159" }, { "start_pos": "1179", "end_pos": "1179" }, { "start_pos": "1853", "end_pos": "1853" }, { "start_pos": "396", "end_pos": "396" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "411", "end_pos": "411" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "623", "end_pos": "623" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P42859-1.620.620", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O70251-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "O70251-1", "length": 225, "uniprot_id": "EF1B_MOUSE", "protein_name": "Elongation factor 1-beta", "refseq_ac": "NP_061266", "refseq_name": "elongation factor 1-beta", "gene_name": "Eef1b2; Eef1b", "gene_names_uniprotkb": "Eef1b2; Eef1b; Eef1b2", "gene_names_refseq": "2810017J07Rik; EF-1-beta; Eef1b2; Eef1b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "O70251", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70251" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "O70251", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70251" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "O70251", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70251" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70251", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70251", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "O70251", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70251" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70251-1.106.106", "start_pos": 106, "end_pos": 106, "uniprot_canonical_ac": "O70251-1", "length": 225, "uniprot_id": "EF1B_MOUSE", "protein_name": "Elongation factor 1-beta", "refseq_ac": "NP_061266", "refseq_name": "elongation factor 1-beta", "gene_name": "Eef1b2; Eef1b", "gene_names_uniprotkb": "Eef1b2; Eef1b; Eef1b2", "gene_names_refseq": "2810017J07Rik; EF-1-beta; Eef1b2; Eef1b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.", "journal": "Journal of proteome research", "date": "2008", "authors": "Zhou H, Ye M, Dong J, Han G, Jiang X, Wu R, Zou H", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTTGSGAADAKDDDDIDLFG", "down_seq": "DDEEESEEAKKLREERLAQY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "site_lbl": "Ser106" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O70251-1.88.88", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70251-1.174.174", "start_pos": 174, "end_pos": 174, "uniprot_canonical_ac": "O70251-1", "length": 225, "uniprot_id": "EF1B_MOUSE", "protein_name": "Elongation factor 1-beta", "refseq_ac": "NP_061266", "refseq_name": "elongation factor 1-beta", "gene_name": "Eef1b2; Eef1b", "gene_names_uniprotkb": "Eef1b2; Eef1b; Eef1b2", "gene_names_refseq": "2810017J07Rik; EF-1-beta; Eef1b2; Eef1b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DMTKLEECVRSIQADGLVWG", "down_seq": "SKLVPVGYGIKKLQIQCVVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "site_lbl": "Ser174" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O70251-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "O70251-1", "length": 225, "uniprot_id": "EF1B_MOUSE", "protein_name": "Elongation factor 1-beta", "refseq_ac": "NP_061266", "refseq_name": "elongation factor 1-beta", "gene_name": "Eef1b2; Eef1b", "gene_names_uniprotkb": "Eef1b2; Eef1b; Eef1b2", "gene_names_refseq": "2810017J07Rik; EF-1-beta; Eef1b2; Eef1b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KSYIEGYVPSQADVAVFEAV", "down_seq": "GPPPADLCHALRWYNHIKSY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "site_lbl": "Ser42" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O70251-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "O70251-1", "length": 225, "uniprot_id": "EF1B_MOUSE", "protein_name": "Elongation factor 1-beta", "refseq_ac": "NP_061266", "refseq_name": "elongation factor 1-beta", "gene_name": "Eef1b2; Eef1b", "gene_names_uniprotkb": "Eef1b2; Eef1b; Eef1b2", "gene_names_refseq": "2810017J07Rik; EF-1-beta; Eef1b2; Eef1b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EKEKASLPGVKKSLGKYGPS", "down_seq": "VEDTTGSGAADAKDDDDIDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "site_lbl": "Ser83" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "O70251-1.88.88", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70251-1.88.88", "start_pos": 88, "end_pos": 88, "uniprot_canonical_ac": "O70251-1", "length": 225, "uniprot_id": "EF1B_MOUSE", "protein_name": "Elongation factor 1-beta", "refseq_ac": "NP_061266", "refseq_name": "elongation factor 1-beta", "gene_name": "Eef1b2; Eef1b", "gene_names_uniprotkb": "Eef1b2; Eef1b; Eef1b2", "gene_names_refseq": "2810017J07Rik; EF-1-beta; Eef1b2; Eef1b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SLPGVKKSLGKYGPSSVEDT", "down_seq": "GSGAADAKDDDDIDLFGSDD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "O70251", "url": "https://www.uniprot.org/uniprotkb/O70251" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O70251", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70251" } ], "site_lbl": "Thr88" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "O70251-1.83.83", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O70251-1.106.106", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17183-1.102.102", "start_pos": 102, "end_pos": 102, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ISVVEQEKLDNLMLELDGTE", "down_seq": "KSKFGANAILGVSLAVCKAG", "glycosylation": [ { "glytoucan_ac": "G57317CE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "IAPALISSGISVVEQEKLDNLMLELDGTENK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn102", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17183-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17183", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17183" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] } ], "crossref": [ { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17183", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17183", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "P17183", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17183" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17183-1.263.263", "start_pos": 263, "end_pos": 263, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GMDVAASEFYRDGKYDLDFK", "down_seq": "PADPSRYITGDQLGALYQDF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "site_lbl": "Ser263" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17183-1.26.26", "start_pos": 26, "end_pos": 26, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IWAREILDSRGNPTVEVDLY", "down_seq": "AKGLFRAAVPSGASTGIYEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "site_lbl": "Thr26" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "P17183-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17183-1.287.287", "start_pos": 287, "end_pos": 287, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PSRYITGDQLGALYQDFVRN", "down_seq": "PVVSIEDPFDQDDWAAWSKF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "site_lbl": "Tyr287" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P17183-1.291.291", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17183-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ITGDQLGALYQDFVRNYPVV", "down_seq": "IEDPFDQDDWAAWSKFTANV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "site_lbl": "Ser291" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P17183-1.287.287", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17183-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LYTAKGLFRAAVPSGASTGI", "down_seq": "EALELRDGDKQRYLGKGVLK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "site_lbl": "Tyr44" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P17183-1.26.26", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17183-1.80.80", "start_pos": 80, "end_pos": 80, "uniprot_canonical_ac": "P17183-1", "length": 434, "uniprot_id": "ENOG_MOUSE", "protein_name": "Gamma-enolase", "refseq_ac": "NP_001289571", "refseq_name": "gamma-enolase isoform 2", "gene_name": "Eno2", "gene_names_uniprotkb": "Eno2; Eno-2", "gene_names_refseq": "D6Ertd375e; Eno-2; Eno2; NSE", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17183", "url": "https://www.uniprot.org/uniprotkb/P17183" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol.", "journal": "Proteomics", "date": "2005", "authors": "Vosseller K, Hansen KC, Chalkley RJ, Trinidad JC, Wells L, Hart GW, Burlingame AL", "evidence": [ { "database": "iPTMnet", "id": "P17183-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17183-1" } ], "reference": [ { "type": "PubMed", "id": "15648052", "url": "https://glygen.org/publication/PubMed/15648052" } ] } ], "crossref": [ { "id": "P17183", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P17183", "database": "PRO", "categories": [ "Other" ] }, { "id": "P17183", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17183", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15648052", "url": "https://glygen.org/publication/PubMed/15648052", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KGVLKAVDHINSRIAPALIS", "down_seq": "GISVVEQEKLDNLMLELDGT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "PRO", "id": "P17183", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P17183" }, { "database": "iPTMnet", "id": "P17183", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P17183" }, { "database": "PubMed", "id": "15648052", "url": "https://glygen.org/publication/PubMed/15648052" } ], "site_lbl": "Ser80" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "102", "end_pos": "102" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "26", "end_pos": "26" }, { "start_pos": "287", "end_pos": "287" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "44", "end_pos": "44" }, { "start_pos": "80", "end_pos": "80" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.107.107", "start_pos": 107, "end_pos": 107, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3389132192", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389132192", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KLIINSLYKNKEIFLRELIS", "down_seq": "ASDALDKIRLISLTDENALA", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ELISNASDALDK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn107", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn107", "evidence": [ { "id": "P08113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389132192", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389132192" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NAS->IAS).", "chr_id": "10", "chr_pos": "86531540", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N107", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P08113-1.103.103", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.217.217", "start_pos": 217, "end_pos": 217, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" }, { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VGFYSAFLVADKVIVTSKHN", "down_seq": "DTQHIWESDSNEFSVIADPR", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G14260UH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G14994KB", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G25637MV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G31852PQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VIVTSKHNNDTQHIWESDSNEFSVIADPR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G48584BU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G66538GV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G74724QE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn217", "evidence": [ { "id": "P08113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P08113-1.219.219", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P08113-1.225.225", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P08113-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 13 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 12 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 12 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 12 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 12 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 12 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.219.219", "start_pos": 219, "end_pos": 219, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" }, { "database": "O-GlcNAc Atlas", "id": "P08113", "url": "https://oglcnac.org/atlas/detail/P08113" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://oglcnac.org/atlas/detail/P08113", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FYSAFLVADKVIVTSKHNND", "down_seq": "QHIWESDSNEFSVIADPRGN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr219", "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P08113", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" }, { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "P08113", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P08113" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P08113-1.217.217", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P08113-1.225.225", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P08113-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.225.225", "start_pos": 225, "end_pos": 225, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" }, { "database": "O-GlcNAc Atlas", "id": "P08113", "url": "https://oglcnac.org/atlas/detail/P08113" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VADKVIVTSKHNNDTQHIWE", "down_seq": "DSNEFSVIADPRGNTLGRGT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser225", "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P08113", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" }, { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P08113-1.217.217", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P08113-1.219.219", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P08113-1.230.230", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.445.445", "start_pos": 445, "end_pos": 445, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MMPKYLNFVKGVVDSDDLPL", "down_seq": "VSRETLQQHKLLKVIRKKLV", "glycosylation": [ { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn445", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn445", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn445", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GVVDSDDLPLNVSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn445", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn445", "evidence": [ { "id": "P08113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P08113-1.447.447", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.481.481", "start_pos": 481, "end_pos": 481, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RKKLVRKTLDMIKKIADEKY", "down_seq": "DTFWKEFGTNIKLGVIEDHS", "glycosylation": [ { "glytoucan_ac": "G08290VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "IADEKYNDTFWK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn481", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn481", "evidence": [ { "id": "P08113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P08113-1.483.483", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.502.502", "start_pos": 502, "end_pos": 502, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DTFWKEFGTNIKLGVIEDHS", "down_seq": "RTRLAKLLRFQSSHHSTDIT", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LGVIEDHSNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "P08113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P08113-1.483.483", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 6 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 6 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 6 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 6 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.62.62", "start_pos": 62, "end_pos": 62, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2287", "url": "https://glyconnect.expasy.org/browser/proteins/2287", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SRTDDEVVQREEEAIQLDGL", "down_seq": "ASQIRELREKSEKFAFQAEV", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G14260UH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G25637MV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G45883VE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G49874UX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G66538GV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G74724QE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "G90575OW", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "EEEAIQLDGLNASQIR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G94854LT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2287", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2287" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "P08113", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08113#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P08113-1.64.64", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 14 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 13 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 13 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 13 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 13 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 13 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.64.64", "start_pos": 64, "end_pos": 64, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" }, { "database": "O-GlcNAc Atlas", "id": "P08113", "url": "https://oglcnac.org/atlas/detail/P08113" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TDDEVVQREEEAIQLDGLNA", "down_seq": "QIRELREKSEKFAFQAEVNR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser64", "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P08113", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" }, { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "site_lbl": "Ser64" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P08113-1.62.62", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08113", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "P08113", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08113" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.103.103", "start_pos": 103, "end_pos": 103, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone.", "journal": "Nature communications", "date": "2010", "authors": "Liu B, Yang Y, Qiu Z, Staron M, Hong F, Li Y, Wu S, Li Y, Hao B, Bona R, Han D, Li Z", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "reference": [ { "type": "PubMed", "id": "20865800", "url": "https://glygen.org/publication/PubMed/20865800" } ] } ], "crossref": [ { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20865800", "url": "https://glygen.org/publication/PubMed/20865800", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "NRMMKLIINSLYKNKEIFLR", "down_seq": "LISNASDALDKIRLISLTDE", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Loss of CNPY3-binding.", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" }, { "database": "PubMed", "id": "20865800", "url": "https://glygen.org/publication/PubMed/20865800" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P08113-1.107.107", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08113-1.230.230", "start_pos": 230, "end_pos": 230, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3401515795", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3401515795", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "IVTSKHNNDTQHIWESDSNE", "down_seq": "SVIADPRGNTLGRGTTITLV", "snv": [ { "evidence": [ { "id": "rs3401515795", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3401515795" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "F", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NEF->NEC).", "chr_id": "10", "chr_pos": "86530007", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "F230", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P08113-1.217.217", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "P08113-1.219.219", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P08113-1.225.225", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08113-1.483.483", "start_pos": 483, "end_pos": 483, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389096969", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389096969", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KLVRKTLDMIKKIADEKYND", "down_seq": "FWKEFGTNIKLGVIEDHSNR", "snv": [ { "evidence": [ { "id": "rs3389096969", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389096969" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NDT->NDA).", "chr_id": "10", "chr_pos": "86530411", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T483", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P08113-1.481.481", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P08113-1.502.502", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08113-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VGMTREELVKNLGTIAKSGT", "down_seq": "EFLNKMTEAQEDGQSTSELI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "site_lbl": "Ser172" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08113-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TETVEEPLEEDEAAKEEKEE", "down_seq": "DDEAAVEEEEEEKKPKTKKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "site_lbl": "Ser306" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08113-1.403.403", "start_pos": 403, "end_pos": 403, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FKSILFVPTSAPRGLFDEYG", "down_seq": "KKSDYIKLYVRRVFITDDFH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "site_lbl": "Ser403" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08113-1.447.447", "start_pos": 447, "end_pos": 447, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKYLNFVKGVVDSDDLPLNV", "down_seq": "RETLQQHKLLKVIRKKLVRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "site_lbl": "Ser447" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P08113-1.445.445", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08113-1.785.785", "start_pos": 785, "end_pos": 785, "uniprot_canonical_ac": "P08113-1", "length": 802, "uniprot_id": "ENPL_MOUSE", "protein_name": "Endoplasmin", "refseq_ac": "NP_035761", "refseq_name": "endoplasmin precursor", "gene_name": "Hsp90b1", "gene_names_uniprotkb": "Hsp90b1; Grp94; Hspc4; Tra-1; Tra1", "gene_names_refseq": "ERp99; GRP94; Hsp90b1; TA-3; Targ2; Tra-1; Tra1; endoplasmin; gp96", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DTSEDAEDSEQDEGEEMDAG", "down_seq": "EEEEEETEKESTEKDEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P08113", "url": "https://www.uniprot.org/uniprotkb/P08113" } ], "site_lbl": "Thr785" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "217", "end_pos": "217" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "225", "end_pos": "225" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "481", "end_pos": "481" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "64", "end_pos": "64" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "103", "end_pos": "103" } ] }, { "type": "snv", "site_list": [ { "start_pos": "107", "end_pos": "107" }, { "start_pos": "230", "end_pos": "230" }, { "start_pos": "483", "end_pos": "483" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "172", "end_pos": "172" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "403", "end_pos": "403" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "64", "end_pos": "64" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08046-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HLTTESFSDIALNNEKAMVE", "down_seq": "SYPSQTTRLPPITYTGRFSL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr116", "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P08046", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "P08046", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P08046" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "P08046-1.117.117", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P08046-1.129.129", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08046", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LTTESFSDIALNNEKAMVET", "down_seq": "YPSQTTRLPPITYTGRFSLE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser117", "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P08046", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P08046" }, { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "P08046", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P08046" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "P08046-1.116.116", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P08046-1.129.129", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.129.129", "start_pos": 129, "end_pos": 129, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P08046", "url": "https://oglcnac.org/atlas/detail/P08046", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NEKAMVETSYPSQTTRLPPI", "down_seq": "YTGRFSLEPAPNSGNTLWPE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" }, { "id": "P08046", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P08046" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P08046-1.116.116", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "P08046-1.117.117", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.348.348", "start_pos": 348, "end_pos": 348, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Jain N, Mahendran R, Philp R, Guy GR, Tan YH, Cao X", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" } ], "reference": [ { "type": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ] } ], "crossref": [ { "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTPPHERPYACPVESCDRRF", "down_seq": "RSDELTRHIRIHTGQKPFQC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O54833-1", "kinase_gene_name": "Csnk2a2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Ser348" }, { "kinase_uniprot_canonical_ac": "Q60737-1", "kinase_gene_name": "Csnk2a1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Ser348" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "P08046-1.361.361", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.361.361", "start_pos": 361, "end_pos": 361, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Jain N, Mahendran R, Philp R, Guy GR, Tan YH, Cao X", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" } ], "reference": [ { "type": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ] } ], "crossref": [ { "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ESCDRRFSRSDELTRHIRIH", "down_seq": "GQKPFQCRICMRNFSRSDHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O54833-1", "kinase_gene_name": "Csnk2a2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Thr361" }, { "kinase_uniprot_canonical_ac": "Q60737-1", "kinase_gene_name": "Csnk2a1", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Thr361" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P08046-1.348.348", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P08046-1.376.376", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.376.376", "start_pos": 376, "end_pos": 376, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Jain N, Mahendran R, Philp R, Guy GR, Tan YH, Cao X", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" } ], "reference": [ { "type": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ] } ], "crossref": [ { "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HIRIHTGQKPFQCRICMRNF", "down_seq": "RSDHLTTHIRTHTGEKPFAC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O54833-1", "kinase_gene_name": "Csnk2a2", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Ser376" }, { "kinase_uniprot_canonical_ac": "Q60737-1", "kinase_gene_name": "Csnk2a1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Ser376" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P08046-1.361.361", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P08046-1.389.389", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.389.389", "start_pos": 389, "end_pos": 389, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Jain N, Mahendran R, Philp R, Guy GR, Tan YH, Cao X", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" } ], "reference": [ { "type": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ] } ], "crossref": [ { "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RICMRNFSRSDHLTTHIRTH", "down_seq": "GEKPFACDICGRKFARSDER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O54833-1", "kinase_gene_name": "Csnk2a2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Thr389" }, { "kinase_uniprot_canonical_ac": "Q60737-1", "kinase_gene_name": "Csnk2a1", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Thr389" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P08046-1.376.376", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08046-1.516.516", "start_pos": 516, "end_pos": 516, "uniprot_canonical_ac": "P08046-1", "length": 533, "uniprot_id": "EGR1_MOUSE", "protein_name": "Early growth response protein 1", "refseq_ac": "NP_031939", "refseq_name": "early growth response protein 1", "gene_name": "Egr1", "gene_names_uniprotkb": "Egr1; Egr-1; Krox-24", "gene_names_refseq": "A530045N19Rik; ETR103; Egr-1; Egr1; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; Zif268; egr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08046", "url": "https://www.uniprot.org/uniprotkb/P08046" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Jain N, Mahendran R, Philp R, Guy GR, Tan YH, Cao X", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" } ], "reference": [ { "type": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ] } ], "crossref": [ { "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FPTQVSSFPSAGVSSSFSTS", "down_seq": "GLSDMTATFSPRTIEIC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O54833-1", "kinase_gene_name": "Csnk2a2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Thr516" }, { "kinase_uniprot_canonical_ac": "Q60737-1", "kinase_gene_name": "Csnk2a1", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P08046", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P08046" }, { "database": "PubMed", "id": "8662759", "url": "https://glygen.org/publication/PubMed/8662759" } ], "site_lbl": "Thr516" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "117", "end_pos": "117" }, { "start_pos": "129", "end_pos": "129" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "361", "end_pos": "361" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "516", "end_pos": "516" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NGLKMIISTMEPQVSNGPTS", "down_seq": "TSNGPSSNNRNCPSPMQTGA", "glycosylation": [ { "glytoucan_ac": "G27947YN", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MIISTMEPQVSNGPTSNTSNGPSSNNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn24", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "Q61701-1.38.38", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.149.149", "start_pos": 149, "end_pos": 149, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.", "journal": "PloS one", "date": "2015", "authors": "Vanevski F, Xu B", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "25692578", "url": "https://glygen.org/publication/PubMed/25692578" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25692578", "url": "https://glygen.org/publication/PubMed/25692578", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PSSASIRDANLYVSGLPKTM", "down_seq": "QKELEQLFSQYGRIITSRIL", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Decreased dendritic localization and decreased translation of reporter mRNA, when associated with Ala-165.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "25692578", "url": "https://glygen.org/publication/PubMed/25692578" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q61701-1.165.165", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.", "journal": "PloS one", "date": "2015", "authors": "Vanevski F, Xu B", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "25692578", "url": "https://glygen.org/publication/PubMed/25692578" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25692578", "url": "https://glygen.org/publication/PubMed/25692578", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PKTMTQKELEQLFSQYGRII", "down_seq": "SRILVDQVTGVSRGVGFIRF", "mutagenesis": [ { "sequence_org": "T", "sequence_mut": "A", "comment": "Decreased dendritic localization and decreased translation of reporter mRNA, when associated with Ala-149.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "25692578", "url": "https://glygen.org/publication/PubMed/25692578" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q61701-1.149.149", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.1.215", "start_pos": 1, "end_pos": 215, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.", "journal": "Molecular cell", "date": "2009", "authors": "Fukao A, Sasano Y, Imataka H, Inoue K, Sakamoto H, Sonenberg N, Thoma C, Fujiwara T", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "MEWNGLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFA", "start_aa": "M", "up_seq": "", "down_seq": "NNPSQKSSQALLSQLYQSPN", "mutagenesis": [ { "sequence_org": "MEWNGLKMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFA", "sequence_mut": "", "comment": "Reduced association with polysomes and reduced stimulation of translation.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "Q61701-1.233.233", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.277.277", "start_pos": 277, "end_pos": 277, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.", "journal": "Molecular cell", "date": "2009", "authors": "Fukao A, Sasano Y, Imataka H, Inoue K, Sakamoto H, Sonenberg N, Thoma C, Fujiwara T", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "MAYGVKRLMSGPVPPSACPP", "down_seq": "FSPITIDGMTSLVGMNIPGH", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No impact on interaction with EIF4A.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q61701-1.278.278", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q61701-1.279.279", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q61701-1.280.280", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.278.278", "start_pos": 278, "end_pos": 278, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.", "journal": "Molecular cell", "date": "2009", "authors": "Fukao A, Sasano Y, Imataka H, Inoue K, Sakamoto H, Sonenberg N, Thoma C, Fujiwara T", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "AYGVKRLMSGPVPPSACPPR", "down_seq": "SPITIDGMTSLVGMNIPGHT", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Disrupts interaction with EIF4A and fails to stimulate translation.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q61701-1.277.277", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q61701-1.279.279", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q61701-1.280.280", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.", "journal": "Molecular cell", "date": "2009", "authors": "Fukao A, Sasano Y, Imataka H, Inoue K, Sakamoto H, Sonenberg N, Thoma C, Fujiwara T", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YGVKRLMSGPVPPSACPPRF", "down_seq": "PITIDGMTSLVGMNIPGHTG", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "No impact on interaction with EIF4A.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q61701-1.277.277", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q61701-1.278.278", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q61701-1.280.280", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.280.280", "start_pos": 280, "end_pos": 280, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.", "journal": "Molecular cell", "date": "2009", "authors": "Fukao A, Sasano Y, Imataka H, Inoue K, Sakamoto H, Sonenberg N, Thoma C, Fujiwara T", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "GVKRLMSGPVPPSACPPRFS", "down_seq": "ITIDGMTSLVGMNIPGHTGT", "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "A", "comment": "No impact on interaction with EIF4A.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q61701-1.277.277", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q61701-1.278.278", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q61701-1.279.279", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.303.385", "start_pos": 303, "end_pos": 385, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner.", "journal": "Molecular cell", "date": "2009", "authors": "Fukao A, Sasano Y, Imataka H, Inoue K, Sakamoto H, Sonenberg N, Thoma C, Fujiwara T", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "reference": [ { "type": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS", "start_aa": "C", "up_seq": "IDGMTSLVGMNIPGHTGTGW", "down_seq": "", "mutagenesis": [ { "sequence_org": "CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHKS", "sequence_mut": "", "comment": "Loss of association with polysomes and loss of translation stimulation.", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "20064466", "url": "https://glygen.org/publication/PubMed/20064466" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q61701-1.382.382", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.314.314", "start_pos": 314, "end_pos": 314, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388699711", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388699711", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "IPGHTGTGWCIFVYNLSPDS", "down_seq": "ESVLWQLFGPFGAVNNVKVI", "snv": [ { "evidence": [ { "id": "rs3388699711", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388699711" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DES->NES).", "chr_id": "4", "chr_pos": "110063747", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D314", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61701-1.382.382", "start_pos": 382, "end_pos": 382, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388700094", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388700094", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "SLNGYRLGDRVLQVSFKTNK", "down_seq": "HKS", "snv": [ { "evidence": [ { "id": "rs3388700094", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388700094" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NKA->NKT).", "chr_id": "4", "chr_pos": "110063543", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A382", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q61701-1.303.385", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61701-1.233.233", "start_pos": 233, "end_pos": 233, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "iPTMnet", "id": "Q61701", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61701" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61701", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61701", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KFANNPSQKSSQALLSQLYQ", "down_seq": "PNRRYPGPLHHQAQRFRLDN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q61701", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61701" } ], "site_lbl": "Ser233" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q61701-1.1.215", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61701-1.38.38", "start_pos": 38, "end_pos": 38, "uniprot_canonical_ac": "Q61701-1", "length": 385, "uniprot_id": "ELAV4_MOUSE", "protein_name": "ELAV-like protein 4", "refseq_ac": "NP_001033787", "refseq_name": "ELAV-like protein 4 isoform b", "gene_name": "Elavl4", "gene_names_uniprotkb": "Elavl4; Hud", "gene_names_refseq": "Elavl4; Elav; Hud; PNEM", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "iPTMnet", "id": "Q61701", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61701" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61701", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61701", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNGPTSNTSNGPSSNNRNCP", "down_seq": "PMQTGAATDDSKTNLIVNYL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q61701", "url": "https://www.uniprot.org/uniprotkb/Q61701" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q61701", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q61701" } ], "site_lbl": "Ser38" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "24", "end_pos": "24" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "149", "end_pos": "149" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "1", "end_pos": "215" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "303", "end_pos": "385" } ] }, { "type": "snv", "site_list": [ { "start_pos": "314", "end_pos": "314" }, { "start_pos": "382", "end_pos": "382" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "233", "end_pos": "233" }, { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q61701-1.24.24", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BG67-1.333.333", "start_pos": 333, "end_pos": 333, "uniprot_canonical_ac": "Q8BG67-1", "length": 819, "uniprot_id": "EFR3A_MOUSE", "protein_name": "Protein EFR3 homolog A", "refseq_ac": "NP_598527", "refseq_name": "protein EFR3 homolog A isoform 1", "gene_name": "Efr3a", "gene_names_uniprotkb": "Efr3a; Kiaa0143", "gene_names_refseq": "A130089M23Rik; C920006C10Rik; D030063F01Rik; Efr3a; mKIAA0143", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3389357828", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389357828", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GIIQVLLEAVAIAAKGSIGP", "down_seq": "VLEVFNTLLKHLRLSVELEA", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389357828", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389357828" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->I).", "chr_id": "15", "chr_pos": "65720003", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T333", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "snv", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "363", "end_pos": "363" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "692", "end_pos": "692" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BG67-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8BG67-1", "length": 819, "uniprot_id": "EFR3A_MOUSE", "protein_name": "Protein EFR3 homolog A", "refseq_ac": "NP_598527", "refseq_name": "protein EFR3 homolog A isoform 1", "gene_name": "Efr3a", "gene_names_uniprotkb": "Efr3a; Kiaa0143", "gene_names_refseq": "A130089M23Rik; C920006C10Rik; D030063F01Rik; Efr3a; mKIAA0143", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BG67", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BG67" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BG67", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BG67", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q8BG67", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BG67" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "snv", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "363", "end_pos": "363" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "692", "end_pos": "692" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BG67-1.360.360", "start_pos": 360, "end_pos": 360, "uniprot_canonical_ac": "Q8BG67-1", "length": 819, "uniprot_id": "EFR3A_MOUSE", "protein_name": "Protein EFR3 homolog A", "refseq_ac": "NP_598527", "refseq_name": "protein EFR3 homolog A isoform 1", "gene_name": "Efr3a", "gene_names_uniprotkb": "Efr3a; Kiaa0143", "gene_names_refseq": "A130089M23Rik; C920006C10Rik; D030063F01Rik; Efr3a; mKIAA0143", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" }, { "database": "iPTMnet", "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TLLKHLRLSVELEANDSQKG", "down_seq": "VGSVTVSSKDNDEKIVQNAV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67" } ], "site_lbl": "Ser360" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "snv", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "363", "end_pos": "363" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "692", "end_pos": "692" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8BG67-1.363.363", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BG67-1.363.363", "start_pos": 363, "end_pos": 363, "uniprot_canonical_ac": "Q8BG67-1", "length": 819, "uniprot_id": "EFR3A_MOUSE", "protein_name": "Protein EFR3 homolog A", "refseq_ac": "NP_598527", "refseq_name": "protein EFR3 homolog A isoform 1", "gene_name": "Efr3a", "gene_names_uniprotkb": "Efr3a; Kiaa0143", "gene_names_refseq": "A130089M23Rik; C920006C10Rik; D030063F01Rik; Efr3a; mKIAA0143", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" }, { "database": "iPTMnet", "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KHLRLSVELEANDSQKGSVG", "down_seq": "VTVSSKDNDEKIVQNAVIQT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67" } ], "site_lbl": "Ser363" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "snv", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "363", "end_pos": "363" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "692", "end_pos": "692" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8BG67-1.360.360", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BG67-1.420.420", "start_pos": 420, "end_pos": 420, "uniprot_canonical_ac": "Q8BG67-1", "length": 819, "uniprot_id": "EFR3A_MOUSE", "protein_name": "Protein EFR3 homolog A", "refseq_ac": "NP_598527", "refseq_name": "protein EFR3 homolog A isoform 1", "gene_name": "Efr3a", "gene_names_uniprotkb": "Efr3a; Kiaa0143", "gene_names_refseq": "A130089M23Rik; C920006C10Rik; D030063F01Rik; Efr3a; mKIAA0143", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MMFIMGKVPVFGTSTHTLDI", "down_seq": "QLGDLGTRRIQIMLLRSLLM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "site_lbl": "Ser420" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "snv", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "363", "end_pos": "363" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "692", "end_pos": "692" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BG67-1.692.692", "start_pos": 692, "end_pos": 692, "uniprot_canonical_ac": "Q8BG67-1", "length": 819, "uniprot_id": "EFR3A_MOUSE", "protein_name": "Protein EFR3 homolog A", "refseq_ac": "NP_598527", "refseq_name": "protein EFR3 homolog A isoform 1", "gene_name": "Efr3a", "gene_names_uniprotkb": "Efr3a; Kiaa0143", "gene_names_refseq": "A130089M23Rik; C920006C10Rik; D030063F01Rik; Efr3a; mKIAA0143", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" }, { "database": "iPTMnet", "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YSVERLTVPYVPQVTDEDRL", "down_seq": "RRKSIVDTVSIQVDILSNSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BG67", "url": "https://www.uniprot.org/uniprotkb/Q8BG67" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q8BG67", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BG67" } ], "site_lbl": "Ser692" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "snv", "site_list": [ { "start_pos": "333", "end_pos": "333" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "360", "end_pos": "360" }, { "start_pos": "363", "end_pos": "363" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "692", "end_pos": "692" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.1202.1202", "start_pos": 1202, "end_pos": 1202, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" }, { "database": "O-GlcNAc Atlas", "id": "Q5DTT3", "url": "https://oglcnac.org/atlas/detail/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "https://oglcnac.org/atlas/detail/Q5DTT3", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QNGLSMSLDEVLEPSKVNVV", "down_seq": "STSVTLREQPSPNCIPAMSD", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1202", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q5DTT3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q5DTT3", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q5DTT3" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q5DTT3-1.1203.1203", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.1203.1203", "start_pos": 1203, "end_pos": 1203, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" }, { "database": "O-GlcNAc Atlas", "id": "Q5DTT3", "url": "https://oglcnac.org/atlas/detail/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "https://oglcnac.org/atlas/detail/Q5DTT3", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NGLSMSLDEVLEPSKVNVVS", "down_seq": "TSVTLREQPSPNCIPAMSDV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1203", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q5DTT3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q5DTT3", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q5DTT3" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q5DTT3-1.1202.1202", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.337.337", "start_pos": 337, "end_pos": 337, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RKTETAEKSGRKLKVKKKAV", "down_seq": "PSSNQRVQPKRKASTTAVTL", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.880.880", "start_pos": 880, "end_pos": 880, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" }, { "database": "O-GlcNAc Atlas", "id": "Q5DTT3", "url": "https://oglcnac.org/atlas/detail/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "https://oglcnac.org/atlas/detail/Q5DTT3", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATNMTFPGPNRVLPFINPPT", "down_seq": "RDLELCVQNDQKEVFTGECH", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr880", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q5DTT3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5DTT3" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q5DTT3", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q5DTT3" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.1116.1116", "start_pos": 1116, "end_pos": 1116, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs257228390", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs257228390", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EVQTQSSRDVPSLAMSEYKD", "down_seq": "KCLSASSVKKETPPESLCLL", "snv": [ { "evidence": [ { "id": "rs257228390", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs257228390" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SKC->NKC).", "chr_id": "13", "chr_pos": "3626602", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S1116", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.383.383", "start_pos": 383, "end_pos": 383, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389265998", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389265998", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "SLGRPTSKRTVPRTDNRSCN", "down_seq": "TLKLVKGQFPQKRKRGAEVL", "snv": [ { "evidence": [ { "id": "rs3389265998", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389265998" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NPT->NTT).", "chr_id": "13", "chr_pos": "3639989", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P383", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.1021.1021", "start_pos": 1021, "end_pos": 1021, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SFHPSPLIKTDAVQDVIQHS", "down_seq": "HINNECQPSVEKREDNVECM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "site_lbl": "Ser1021" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.1082.1082", "start_pos": 1082, "end_pos": 1082, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TEVHTTDKPTGFNIELVKRV", "down_seq": "PASSVQYPMSALEEVQTQSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "site_lbl": "Ser1082" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.1430.1430", "start_pos": 1430, "end_pos": 1430, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QIKSGEVTIPEKESLFLGPE", "down_seq": "PKGQDKLAEVQVQISAEMLQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "site_lbl": "Ser1430" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.1540.1540", "start_pos": 1540, "end_pos": 1540, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MENRNVDVKHLALESSVPSC", "down_seq": "PRKVVENKSLTDTLVSITTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "site_lbl": "Ser1540" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.1962.1962", "start_pos": 1962, "end_pos": 1962, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DHKLKQIKKGGSQQSSFPKE", "down_seq": "LVQISSGTSPSTQTSEASGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "site_lbl": "Ser1962" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.1990.1990", "start_pos": 1990, "end_pos": 1990, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TSPSTQTSEASGLHLPPESR", "down_seq": "PILVTVVRADTRQQSHHRRG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "site_lbl": "Ser1990" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.19.19", "start_pos": 19, "end_pos": 19, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MAAPTSKIILELNKNALI", "down_seq": "PWKGQFIIQGCLLCDITLWS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "site_lbl": "Ser19" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.2012.2012", "start_pos": 2012, "end_pos": 2012, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ILVTVVRADTRQQSHHRRGC", "down_seq": "PSSLDGSSSFWKKKCSQSRN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "site_lbl": "Ser2012" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q5DTT3-1.2015.2015", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q5DTT3-1.2019.2019", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.2015.2015", "start_pos": 2015, "end_pos": 2015, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TVVRADTRQQSHHRRGCSPS", "down_seq": "LDGSSSFWKKKCSQSRNLKN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5DTT3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5DTT3" } ], "site_lbl": "Ser2015" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q5DTT3-1.2012.2012", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q5DTT3-1.2019.2019", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5DTT3-1.2019.2019", "start_pos": 2019, "end_pos": 2019, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ADTRQQSHHRRGCSPSSLDG", "down_seq": "SSFWKKKCSQSRNLKNSERS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "site_lbl": "Ser2019" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q5DTT3-1.2012.2012", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q5DTT3-1.2015.2015", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5DTT3-1.219.219", "start_pos": 219, "end_pos": 219, "uniprot_canonical_ac": "Q5DTT3-1", "length": 2382, "uniprot_id": "TASO2_MOUSE", "protein_name": "Protein TASOR 2", "refseq_ac": "NP_598824", "refseq_name": "protein TASOR 2 isoform 1", "gene_name": "Tasor2", "gene_names_uniprotkb": "Tasor2; Fam208b; Kiaa2006; Pap20", "gene_names_refseq": "Fam208b; Pap20; Tasor2; mKIAA2006", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GIPPNILVKHSFQELYKVDK", "down_seq": "LSLMAPPQDGVEDTASTGKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5DTT3", "url": "https://www.uniprot.org/uniprotkb/Q5DTT3" } ], "site_lbl": "Ser219" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1202", "end_pos": "1202" }, { "start_pos": "1203", "end_pos": "1203" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "880", "end_pos": "880" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1116", "end_pos": "1116" }, { "start_pos": "383", "end_pos": "383" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1082", "end_pos": "1082" }, { "start_pos": "1430", "end_pos": "1430" }, { "start_pos": "1540", "end_pos": "1540" }, { "start_pos": "1962", "end_pos": "1962" }, { "start_pos": "1990", "end_pos": "1990" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "2012", "end_pos": "2012" }, { "start_pos": "2015", "end_pos": "2015" }, { "start_pos": "2019", "end_pos": "2019" }, { "start_pos": "219", "end_pos": "219" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09127-1.300.300", "start_pos": 300, "end_pos": 300, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YKSAPGDQLCARCPPHSHSA", "down_seq": "PAAQTCRCDLSYYRAALDPP", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr300", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09127-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PPSAACTRPPSAPVNLISSV", "down_seq": "GTSVTLEWAPPLDPGGRSDI", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn339", "evidence": [ { "id": "O09127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O09127#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "O09127-1.358.358", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09127-1.406.406", "start_pos": 406, "end_pos": 406, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PQQTSLAQASLLVANLLAHM", "down_seq": "YSFWIEAVNGVSNLSPEPRS", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn406", "evidence": [ { "id": "O09127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O09127#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09127-1.431.431", "start_pos": 431, "end_pos": 431, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IEAVNGVSNLSPEPRSAAVV", "down_seq": "ITTNQAAPSQVVVIRQERAG", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SAAVVNITTNQAAPSQVVVIR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn431", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn431", "evidence": [ { "id": "O09127", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O09127#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09127-1.615.615", "start_pos": 615, "end_pos": 615, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation at Tyr-838 in the kinase domain of EphA8 modulates Fyn binding to the Tyr-615 site by enhancing tyrosine kinase activity.", "journal": "Oncogene", "date": "1999", "authors": "Choi S, Park S", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "iPTMnet", "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127" } ], "reference": [ { "type": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" } ] }, { "title": "The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner.", "journal": "Molecular and cellular biology", "date": "2001", "authors": "Gu C, Park S", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "reference": [ { "type": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] } ], "crossref": [ { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "O09127", "url": "https://www.ebi.ac.uk/intact/interactors/id:O09127*", "database": "IntAct", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PLNHPPGKFPETQFSAEPHT", "down_seq": "EEPGRAGRSFTREIEASRIH", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduced phosphorylation and reduced association with FYN.", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" }, { "database": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O09127-1", "kinase_gene_name": "Epha8", "residue": "Tyr", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "iPTMnet", "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127" }, { "database": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" } ], "site_lbl": "Tyr615" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "IntAct", "id": "O09127", "url": "https://www.ebi.ac.uk/intact/interactors/id:O09127*" }, { "database": "iPTMnet", "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127" }, { "database": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" } ], "site_lbl": "Tyr615" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09127-1.666.666", "start_pos": 666, "end_pos": 666, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner.", "journal": "Molecular and cellular biology", "date": "2001", "authors": "Gu C, Park S", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "reference": [ { "type": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] } ], "crossref": [ { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "GEVCYGRLQVPGQRDVPVAI", "down_seq": "ALKAGYTERQRQDFLSEAAI", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "M", "comment": "Kinase-dead. Loss of autophosphorylation but has no effect on regulation of cell adhesion.", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] }, { "sequence_org": "K", "sequence_mut": "R", "comment": "Kinase-dead. Loss of autophosphorylation but has no effect on regulation of cell adhesion.", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09127-1.792.792", "start_pos": 792, "end_pos": 792, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The EphA8 receptor regulates integrin activity through p110gamma phosphatidylinositol-3 kinase in a tyrosine kinase activity-independent manner.", "journal": "Molecular and cellular biology", "date": "2001", "authors": "Gu C, Park S", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "reference": [ { "type": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] } ], "crossref": [ { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "VCKVSDFGLSRALEDDPEAA", "down_seq": "TTAGGKIPIRWTAPEAIAFR", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduced phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "PubMed", "id": "11416136", "url": "https://glygen.org/publication/PubMed/11416136" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09127-1.838.838", "start_pos": 838, "end_pos": 838, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation at Tyr-838 in the kinase domain of EphA8 modulates Fyn binding to the Tyr-615 site by enhancing tyrosine kinase activity.", "journal": "Oncogene", "date": "1999", "authors": "Choi S, Park S", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "iPTMnet", "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127" } ], "reference": [ { "type": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" } ] } ], "crossref": [ { "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SDVWSFGVVMWEVLAYGERP", "down_seq": "WNMTNQDVISSVEEGYRLPA", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduced tyrosine kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O09127-1", "kinase_gene_name": "Epha8", "residue": "Tyr", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" }, { "database": "iPTMnet", "id": "O09127", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09127" }, { "database": "PubMed", "id": "10498895", "url": "https://glygen.org/publication/PubMed/10498895" } ], "site_lbl": "Tyr838" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "site_lbl": "Tyr838" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09127-1.358.358", "start_pos": 358, "end_pos": 358, "uniprot_canonical_ac": "O09127-1", "length": 1004, "uniprot_id": "EPHA8_MOUSE", "protein_name": "Ephrin type-A receptor 8", "refseq_ac": "NP_031965", "refseq_name": "ephrin type-A receptor 8 isoform 1 precursor", "gene_name": "Epha8", "gene_names_uniprotkb": "Epha8; Eek", "gene_names_refseq": "Eek; Epha8; Hek3; mKIAA1459", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09127", "url": "https://www.uniprot.org/uniprotkb/O09127" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs217801627", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs217801627", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "VNGTSVTLEWAPPLDPGGRS", "down_seq": "ITYNAVCRRCPWALSHCEAC", "snv": [ { "evidence": [ { "id": "rs217801627", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs217801627" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DIT->NIT).", "chr_id": "4", "chr_pos": "136666083", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D358", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "300", "end_pos": "300" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "431", "end_pos": "431" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "666", "end_pos": "666" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "838", "end_pos": "838" } ] }, { "type": "snv", "site_list": [ { "start_pos": "358", "end_pos": "358" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "615", "end_pos": "615" }, { "start_pos": "838", "end_pos": "838" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O09127-1.339.339", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97767-1.99.99", "start_pos": 99, "end_pos": 99, "uniprot_canonical_ac": "P97767-1", "length": 591, "uniprot_id": "EYA1_MOUSE", "protein_name": "Protein phosphatase EYA1", "refseq_ac": "NP_001297388", "refseq_name": "protein phosphatase EYA1 isoform 3", "gene_name": "Eya1", "gene_names_uniprotkb": "Eya1", "gene_names_refseq": "Eya1; bor", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AHPFSPPQIYPSKSYPHILP", "down_seq": "PSSQTMAAYGQTQFTTGMQQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr99", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "99", "end_pos": "99" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "43", "end_pos": "43" }, { "start_pos": "459", "end_pos": "459" } ] }, { "type": "snv", "site_list": [ { "start_pos": "154", "end_pos": "154" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P97767-1.43.43", "start_pos": 43, "end_pos": 43, "uniprot_canonical_ac": "P97767-1", "length": 591, "uniprot_id": "EYA1_MOUSE", "protein_name": "Protein phosphatase EYA1", "refseq_ac": "NP_001297388", "refseq_name": "protein phosphatase EYA1 isoform 3", "gene_name": "Eya1", "gene_names_uniprotkb": "Eya1", "gene_names_refseq": "Eya1; bor", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "SUMO1 haploinsufficiency leads to cleft lip and palate.", "journal": "Science (New York, N.Y.)", "date": "2006", "authors": "Alkuraya FS, Saadi I, Lund JJ, Turbe-Doan A, Morton CC, Maas RL", "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" } ], "reference": [ { "type": "PubMed", "id": "16990542", "url": "https://glygen.org/publication/PubMed/16990542" } ] } ], "crossref": [ { "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16990542", "url": "https://glygen.org/publication/PubMed/16990542", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "PKLDSSHINSTSMTPNGTEV", "down_seq": "TEPMSSSEIASTAADGSLDS", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Markedly reduced sumoylation; when associated with R-459.", "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" }, { "database": "PubMed", "id": "16990542", "url": "https://glygen.org/publication/PubMed/16990542" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "99", "end_pos": "99" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "43", "end_pos": "43" }, { "start_pos": "459", "end_pos": "459" } ] }, { "type": "snv", "site_list": [ { "start_pos": "154", "end_pos": "154" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97767-1.459.459", "start_pos": 459, "end_pos": 459, "uniprot_canonical_ac": "P97767-1", "length": 591, "uniprot_id": "EYA1_MOUSE", "protein_name": "Protein phosphatase EYA1", "refseq_ac": "NP_001297388", "refseq_name": "protein phosphatase EYA1 isoform 3", "gene_name": "Eya1", "gene_names_uniprotkb": "Eya1", "gene_names_refseq": "Eya1; bor", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "SUMO1 haploinsufficiency leads to cleft lip and palate.", "journal": "Science (New York, N.Y.)", "date": "2006", "authors": "Alkuraya FS, Saadi I, Lund JJ, Turbe-Doan A, Morton CC, Maas RL", "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" } ], "reference": [ { "type": "PubMed", "id": "16990542", "url": "https://glygen.org/publication/PubMed/16990542" } ] } ], "crossref": [ { "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16990542", "url": "https://glygen.org/publication/PubMed/16990542", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "RVKEIYNTYKNNVGGLLGPA", "down_seq": "REAWLQLRAEIEALTDSWLT", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Markedly reduced sumoylation; when associated with R-43.", "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" }, { "database": "PubMed", "id": "16990542", "url": "https://glygen.org/publication/PubMed/16990542" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "99", "end_pos": "99" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "43", "end_pos": "43" }, { "start_pos": "459", "end_pos": "459" } ] }, { "type": "snv", "site_list": [ { "start_pos": "154", "end_pos": "154" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P97767-1.154.154", "start_pos": 154, "end_pos": 154, "uniprot_canonical_ac": "P97767-1", "length": 591, "uniprot_id": "EYA1_MOUSE", "protein_name": "Protein phosphatase EYA1", "refseq_ac": "NP_001297388", "refseq_name": "protein phosphatase EYA1 isoform 3", "gene_name": "Eya1", "gene_names_uniprotkb": "Eya1", "gene_names_refseq": "Eya1; bor", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97767", "url": "https://www.uniprot.org/uniprotkb/P97767" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388458342", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388458342", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GISSYGALWAGIKTESGLSQ", "down_seq": "QSPGQTGFLSYGTSFGTPQP", "snv": [ { "evidence": [ { "id": "rs3388458342", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388458342" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SQS->NQS).", "chr_id": "1", "chr_pos": "14323323", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S154", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "99", "end_pos": "99" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "43", "end_pos": "43" }, { "start_pos": "459", "end_pos": "459" } ] }, { "type": "snv", "site_list": [ { "start_pos": "154", "end_pos": "154" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5XG69-1.10.10", "start_pos": 10, "end_pos": 10, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MAFPVDLLD", "down_seq": "CTHEELENSSEDYLSSLRCG", "glycosylation": [ { "glytoucan_ac": "G92050GC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MAFPVDLLDNCTHEELENSSEDYLSSLR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn10", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5XG69-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DHELLWEVEGVGHWHQRVPV", "down_seq": "RALQREAIKATDVSQYEATR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr255", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5XG69-1.348.348", "start_pos": 348, "end_pos": 348, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSHLKRPKIGKHFQDSEFSS", "down_seq": "QGEDENVAKTSPTASVNKIE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "site_lbl": "Ser348" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5XG69-1.377.377", "start_pos": 377, "end_pos": 377, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KTSPTASVNKIEYAARTSES", "down_seq": "EEFLEEEPEQGVIDFEDESG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "site_lbl": "Ser377" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5XG69-1.447.447", "start_pos": 447, "end_pos": 447, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GEVMDAALKPSLTTEDEDST", "down_seq": "EGLEEDLKVPPFNSSGEPGN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "site_lbl": "Ser447" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5XG69-1.512.512", "start_pos": 512, "end_pos": 512, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SEMLIDQSPSDDKGHTEENL", "down_seq": "PVSKKKTLLGSSDNVATVSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "site_lbl": "Ser512" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5XG69-1.610.610", "start_pos": 610, "end_pos": 610, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELEDAPFPQNAGQKSQSEEQ", "down_seq": "EASSEHLEQFTQSAEKAVDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "site_lbl": "Ser610" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q5XG69-1.613.613", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q5XG69-1.630.630", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5XG69-1.613.613", "start_pos": 613, "end_pos": 613, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DAPFPQNAGQKSQSEEQSEA", "down_seq": "SEHLEQFTQSAEKAVDSSSE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "site_lbl": "Ser613" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q5XG69-1.610.610", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q5XG69-1.630.630", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q5XG69-1.630.630", "start_pos": 630, "end_pos": 630, "uniprot_canonical_ac": "Q5XG69-1", "length": 665, "uniprot_id": "F169A_MOUSE", "protein_name": "Soluble lamin-associated protein of 75 kDa", "refseq_ac": "NP_001093928", "refseq_name": "soluble lamin-associated protein of 75 kDa", "gene_name": "Fam169a", "gene_names_uniprotkb": "Fam169a; Kiaa0888", "gene_names_refseq": "B230112C05Rik; Fam169a; SLAP75", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SEASSEHLEQFTQSAEKAVD", "down_seq": "SSEEIEVEVPVVDRRNLRRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q5XG69", "url": "https://www.uniprot.org/uniprotkb/Q5XG69" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q5XG69", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q5XG69" } ], "site_lbl": "Ser630" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "10", "end_pos": "10" }, { "start_pos": "255", "end_pos": "255" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "348", "end_pos": "348" }, { "start_pos": "377", "end_pos": "377" }, { "start_pos": "447", "end_pos": "447" }, { "start_pos": "512", "end_pos": "512" }, { "start_pos": "610", "end_pos": "610" }, { "start_pos": "613", "end_pos": "613" }, { "start_pos": "630", "end_pos": "630" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q5XG69-1.610.610", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q5XG69-1.613.613", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1027.1027", "start_pos": 1027, "end_pos": 1027, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RLPRSESAENHSYAKHSANM", "down_seq": "FSNHNNVRANTGYHLQQRLA", "glycosylation": [ { "glytoucan_ac": "G67350BD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "HSANMNFSNHNNVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1027", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1068.1068", "start_pos": 1068, "end_pos": 1068, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" }, { "database": "O-GlcNAc Atlas", "id": "Q80TH2", "url": "https://oglcnac.org/atlas/detail/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q80TH2", "url": "https://oglcnac.org/atlas/detail/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "https://oglcnac.org/atlas/detail/Q80TH2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PARHGEMWAISPNDRLVPAV", "down_seq": "RTTIQRQSSVSSTASVNLGD", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1068", "evidence": [ { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "Q80TH2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q80TH2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q80TH2" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1093.1093", "start_pos": 1093, "end_pos": 1093, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q80TH2", "url": "https://oglcnac.org/atlas/detail/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "https://oglcnac.org/atlas/detail/Q80TH2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QRQSSVSSTASVNLGDPTRR", "down_seq": "EGDYLSYRELHSMGRTPVMS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1093", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q80TH2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q80TH2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q80TH2-3.1097.1097", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1130.1130", "start_pos": 1130, "end_pos": 1130, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PVMSGSQRPLSARAYSIDGP", "down_seq": "TSRPQSARPSINEIPERTMS", "glycosylation": [ { "glytoucan_ac": "G18647XP", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "AYSIDGPNTSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1130", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q80TH2-3.1132.1132", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q80TH2-3.1150.1150", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1132.1132", "start_pos": 1132, "end_pos": 1132, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" }, { "database": "O-GlcNAc Atlas", "id": "Q80TH2", "url": "https://oglcnac.org/atlas/detail/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSGSQRPLSARAYSIDGPNT", "down_seq": "RPQSARPSINEIPERTMSVS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1132", "evidence": [ { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "Q80TH2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80TH2" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q80TH2-3.1130.1130", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q80TH2-3.1150.1150", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.374.374", "start_pos": 374, "end_pos": 374, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CNKLETLPEEMGDMQKLKVI", "down_seq": "LSDNRLKNLPFSFTKLQQLT", "glycosylation": [ { "glytoucan_ac": "G83460ZZ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VLNLSDNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn374", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.861.861", "start_pos": 861, "end_pos": 861, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3389285277", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389285277", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SADVGISKSTEDLSPQRSGP", "down_seq": "GAVVKSHSITNMETGGLKIY", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr861", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389285277", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389285277" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->I).", "chr_id": "13", "chr_pos": "103971033", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T861", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q80TH2-3.849.849", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q80TH2-3.854.854", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q80TH2-3.869.869", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "McDonald C, Chen FF, Ollendorff V, Ogura Y, Marchetto S, Lecine P, Borg JP, Nunez G", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "16203728", "url": "https://glygen.org/publication/PubMed/16203728" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "16203728", "url": "https://glygen.org/publication/PubMed/16203728", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "IGGLRSIEELDCSFNEIEAL", "down_seq": "SSIGQLTNMRTFAADHNYLQ", "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "L", "comment": "Decreases interaction with NOD2.", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "16203728", "url": "https://glygen.org/publication/PubMed/16203728" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.808.808", "start_pos": 808, "end_pos": 808, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389312643", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389312643", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "LGTGFLSIHPKNEAEHIENG", "down_seq": "KFPNLESINKVNGLCEDTAP", "snv": [ { "evidence": [ { "id": "rs3389312643", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389312643" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NGA->NGT).", "chr_id": "13", "chr_pos": "103971193", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A808", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.837.837", "start_pos": 837, "end_pos": 837, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389309772", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389309772", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "NKVNGLCEDTAPSPGRVEPQ", "down_seq": "ASSSADVGISKSTEDLSPQR", "snv": [ { "evidence": [ { "id": "rs3389309772", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389309772" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KAS->NAS).", "chr_id": "13", "chr_pos": "103971104", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K837", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q80TH2-3.849.849", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q80TH2-3.854.854", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.1097.1097", "start_pos": 1097, "end_pos": 1097, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Cao L, Yu K, Banh C, Nguyen V, Ritz A, Raphael BJ, Kawakami Y, Kawakami T, Salomon AR", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SVSSTASVNLGDPTRRTEGD", "down_seq": "LSYRELHSMGRTPVMSGSQR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Tyr1097" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q80TH2-3.1093.1093", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1150.1150", "start_pos": 1150, "end_pos": 1150, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NTSRPQSARPSINEIPERTM", "down_seq": "VSDFNYSRTSPSKRPNTRVG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser1150" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q80TH2-3.1130.1130", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q80TH2-3.1132.1132", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.1171.1171", "start_pos": 1171, "end_pos": 1171, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VSDFNYSRTSPSKRPNTRVG", "down_seq": "EHSLLDPPGKSKVPHDWREQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Ser1171" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.1276.1276", "start_pos": 1276, "end_pos": 1276, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQAHYSQTHHPPQASVARHP", "down_seq": "REQLIDYLMLKVAHQPPYTH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Ser1276" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.440.440", "start_pos": 440, "end_pos": 440, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MVLTNYMFPQQPRTEDVMFI", "down_seq": "DNESFNPALWEEQRKQRAQV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser440" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q80TH2-3.444.444", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.444.444", "start_pos": 444, "end_pos": 444, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NYMFPQQPRTEDVMFISDNE", "down_seq": "FNPALWEEQRKQRAQVAFEC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser444" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q80TH2-3.440.440", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.483.483", "start_pos": 483, "end_pos": 483, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ECDEDKDEREAPPREGNLKR", "down_seq": "PTPYPDELKNMVKTVQTIVH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Tyr483" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q80TH2-3.485.485", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.485.485", "start_pos": 485, "end_pos": 485, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DEDKDEREAPPREGNLKRYP", "down_seq": "PYPDELKNMVKTVQTIVHRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Thr485" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q80TH2-3.483.483", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.595.595", "start_pos": 595, "end_pos": 595, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SMKLSGNLKHIVNHDDVFEE", "down_seq": "EELSSDEEMKMAEMRPPLIE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser595" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q80TH2-3.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q80TH2-3.600.600", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.599.599", "start_pos": 599, "end_pos": 599, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGNLKHIVNHDDVFEESEEL", "down_seq": "SDEEMKMAEMRPPLIESSIN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser599" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q80TH2-3.595.595", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q80TH2-3.600.600", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q80TH2-3.617.617", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.600.600", "start_pos": 600, "end_pos": 600, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GNLKHIVNHDDVFEESEELS", "down_seq": "DEEMKMAEMRPPLIESSINQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser600" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q80TH2-3.595.595", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q80TH2-3.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q80TH2-3.617.617", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.617.617", "start_pos": 617, "end_pos": 617, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELSSDEEMKMAEMRPPLIES", "down_seq": "INQPKVVALSNNKKDDAKDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Ser617" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q80TH2-3.599.599", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q80TH2-3.600.600", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.712.712", "start_pos": 712, "end_pos": 712, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VRQEDENFNSLLQNGVNLNN", "down_seq": "PEEKFKINDKKDFKLPEYDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser712" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.849.849", "start_pos": 849, "end_pos": 849, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPGRVEPQKASSSADVGISK", "down_seq": "TEDLSPQRSGPTGAVVKSHS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser849" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q80TH2-3.837.837", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q80TH2-3.854.854", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q80TH2-3.861.861", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q80TH2-3.869.869", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.854.854", "start_pos": 854, "end_pos": 854, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPQKASSSADVGISKSTEDL", "down_seq": "PQRSGPTGAVVKSHSITNME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser854" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q80TH2-3.837.837", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q80TH2-3.849.849", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q80TH2-3.861.861", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q80TH2-3.869.869", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.869.869", "start_pos": 869, "end_pos": 869, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STEDLSPQRSGPTGAVVKSH", "down_seq": "ITNMETGGLKIYDILGDDGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q80TH2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q80TH2" } ], "site_lbl": "Ser869" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q80TH2-3.849.849", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q80TH2-3.854.854", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q80TH2-3.861.861", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80TH2-3.914.914", "start_pos": 914, "end_pos": 914, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AAVKIASAVDGKNIVRSKSA", "down_seq": "LLYDQPLQVFTAASSSSELL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Thr914" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q80TH2-3.917.917", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q80TH2-3.928.928", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.917.917", "start_pos": 917, "end_pos": 917, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KIASAVDGKNIVRSKSATLL", "down_seq": "DQPLQVFTAASSSSELLSGT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Tyr917" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q80TH2-3.914.914", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q80TH2-3.928.928", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.928.928", "start_pos": 928, "end_pos": 928, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VRSKSATLLYDQPLQVFTAA", "down_seq": "SSSELLSGTKAVFKFDSNHN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Ser928" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q80TH2-3.914.914", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q80TH2-3.917.917", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80TH2-3.970.970", "start_pos": 970, "end_pos": 970, "uniprot_canonical_ac": "Q80TH2-3", "length": 1402, "uniprot_id": "ERBIN_MOUSE", "protein_name": "Erbin", "refseq_ac": "NP_001005868", "refseq_name": "erbin isoform 1", "gene_name": "Erbin", "gene_names_uniprotkb": "Erbin; Erbb2ip; Kiaa1225; Lap2", "gene_names_refseq": "1700028E05Rik; Erbb2ip; Erbin; mKIAA1225", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "EEPDIIRAATVSGPQSTPHL", "down_seq": "GPPQYNVQYSGSATVKDTLW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q80TH2", "url": "https://www.uniprot.org/uniprotkb/Q80TH2" } ], "site_lbl": "Tyr970" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1027", "end_pos": "1027" }, { "start_pos": "1068", "end_pos": "1068" }, { "start_pos": "1093", "end_pos": "1093" }, { "start_pos": "1130", "end_pos": "1130" }, { "start_pos": "1132", "end_pos": "1132" }, { "start_pos": "374", "end_pos": "374" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "315", "end_pos": "315" } ] }, { "type": "snv", "site_list": [ { "start_pos": "808", "end_pos": "808" }, { "start_pos": "837", "end_pos": "837" }, { "start_pos": "861", "end_pos": "861" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1097", "end_pos": "1097" }, { "start_pos": "1150", "end_pos": "1150" }, { "start_pos": "1171", "end_pos": "1171" }, { "start_pos": "1276", "end_pos": "1276" }, { "start_pos": "440", "end_pos": "440" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "483", "end_pos": "483" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "595", "end_pos": "595" }, { "start_pos": "599", "end_pos": "599" }, { "start_pos": "600", "end_pos": "600" }, { "start_pos": "617", "end_pos": "617" }, { "start_pos": "712", "end_pos": "712" }, { "start_pos": "849", "end_pos": "849" }, { "start_pos": "854", "end_pos": "854" }, { "start_pos": "869", "end_pos": "869" }, { "start_pos": "914", "end_pos": "914" }, { "start_pos": "917", "end_pos": "917" }, { "start_pos": "928", "end_pos": "928" }, { "start_pos": "970", "end_pos": "970" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BMB0-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "HKMNLSLYLGERPSYSMSGP", "down_seq": "SSSEWSIEGRRLVPLMPRLV", "glycosylation": [ { "glytoucan_ac": "G86182NS", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "PSYSMSGPNSSSEWSIEGRR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn101", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.1039.1039", "start_pos": 1039, "end_pos": 1039, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VQPQTPQSQMALPSSEKQPA", "down_seq": "QVEQPIITQGSSVTKITFEG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1039", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.1047.1047", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.1047.1047", "start_pos": 1047, "end_pos": 1047, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QMALPSSEKQPASQVEQPII", "down_seq": "QGSSVTKITFEGRQPPTVTK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1047", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.1039.1039", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.1069.1069", "start_pos": 1069, "end_pos": 1069, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2018", "authors": "Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GSSVTKITFEGRQPPTVTKI", "down_seq": "GGSSVPKLTSPVTSISPIQA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1069", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "29237092", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29237092" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GlcNAc) threonine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1069", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q8BMB0-1.1085.1085", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.1176.1176", "start_pos": 1176, "end_pos": 1176, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PSAVGPPLTTRKIEAAGVPT", "down_seq": "GQFMRIQNVGQKKAEESPTE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1176", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.192.192", "start_pos": 192, "end_pos": 192, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2006", "authors": "Vosseller K, Trinidad JC, Chalkley RJ, Specht CG, Thalhammer A, Lynn AJ, Snedecor JO, Guan S, Medzihradszky KF, Maltby DA, Schoepfer R, Burlingame AL", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" }, { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "16452088", "url": "https://glygen.org/publication/PubMed/16452088" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "16452088", "url": "https://glygen.org/publication/PubMed/16452088", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3388929503", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388929503", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs16805613", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs16805613", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NSSSSSPVVLKEVPKAVVPV", "down_seq": "KTITVPVSGSPKMSNIMQSI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser192", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "16452088", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/16452088" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser192", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" }, { "id": "16452088", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/16452088" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388929503", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388929503" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (S->L).", "chr_id": "7", "chr_pos": "98286616", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S192", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs16805613", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs16805613" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (S->P).", "chr_id": "7", "chr_pos": "98286500", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S192", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BMB0-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8BMB0-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.194.194", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.196.196", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.200.200", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.202.202", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.194.194", "start_pos": 194, "end_pos": 194, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSSSPVVLKEVPKAVVPVSK", "down_seq": "ITVPVSGSPKMSNIMQSIAN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr194", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8BMB0-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.192.192", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.196.196", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.200.200", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.202.202", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSPVVLKEVPKAVVPVSKTI", "down_seq": "VPVSGSPKMSNIMQSIANSL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr196", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BMB0-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.192.192", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.194.194", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.200.200", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.202.202", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.200.200", "start_pos": 200, "end_pos": 200, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases", "journal": "Front Aging", "date": "2021", "authors": "Huynh V.N., Wang S., Ouyang X., Wani W.Y., Johnson M.S., Chacko B.K., Jegga A.G., Qian W.J., Chatham J.C., Darley-Usmar V.M., Zhang J.", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "DOI", "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801", "database": "DOI", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VLKEVPKAVVPVSKTITVPV", "down_seq": "GSPKMSNIMQSIANSLPPHM", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser200", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "10.3389/fragi.2021.757801", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser200", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.192.192", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.194.194", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.196.196", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.202.202", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.226.226", "start_pos": 226, "end_pos": 226, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2018", "authors": "Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SNIMQSIANSLPPHMSPVKI", "down_seq": "FTKPSTQTTNTTTQKVIIVT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr226", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "29237092", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29237092" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.228.228", "start_pos": 228, "end_pos": 228, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2018", "authors": "Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IMQSIANSLPPHMSPVKITF", "down_seq": "KPSTQTTNTTTQKVIIVTTS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr228", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "29237092", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29237092" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.231.231", "start_pos": 231, "end_pos": 231, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "rs16805613", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs16805613", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SIANSLPPHMSPVKITFTKP", "down_seq": "TQTTNTTTQKVIIVTTSPSS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser231", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "snv": [ { "evidence": [ { "id": "rs16805613", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs16805613" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (S->P).", "chr_id": "7", "chr_pos": "98286500", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S231", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.232.232", "start_pos": 232, "end_pos": 232, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IANSLPPHMSPVKITFTKPS", "down_seq": "QTTNTTTQKVIIVTTSPSST", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.234.234", "start_pos": 234, "end_pos": 234, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NSLPPHMSPVKITFTKPSTQ", "down_seq": "TNTTTQKVIIVTTSPSSTFV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr234", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.235.235", "start_pos": 235, "end_pos": 235, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2018", "authors": "Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SLPPHMSPVKITFTKPSTQT", "down_seq": "NTTTQKVIIVTTSPSSTFVP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr235", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "29237092", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29237092" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GlcNAc) threonine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr235", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.236.236", "start_pos": 236, "end_pos": 236, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LPPHMSPVKITFTKPSTQTT", "down_seq": "TTTQKVIIVTTSPSSTFVPN", "glycosylation": [ { "glytoucan_ac": "G59924QI", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "PSTQTTNTTTQK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn236", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.237.237", "start_pos": 237, "end_pos": 237, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PPHMSPVKITFTKPSTQTTN", "down_seq": "TTQKVIIVTTSPSSTFVPNI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr237", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.246.246", "start_pos": 246, "end_pos": 246, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TFTKPSTQTTNTTTQKVIIV", "down_seq": "TSPSSTFVPNILSKSHNYAA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8BMB0-1.226.226", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.247.247", "start_pos": 247, "end_pos": 247, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2018", "authors": "Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FTKPSTQTTNTTTQKVIIVT", "down_seq": "SPSSTFVPNILSKSHNYAAV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr247", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "29237092", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29237092" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TKPSTQTTNTTTQKVIIVTT", "down_seq": "PSSTFVPNILSKSHNYAAVT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser248", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8BMB0-1.228.228", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q8BMB0-1.231.231", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8BMB0-1.232.232", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8BMB0-1.234.234", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8BMB0-1.235.235", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8BMB0-1.236.236", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.246.246", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.247.247", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.323.323", "start_pos": 323, "end_pos": 323, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SSSTSSPISSTVAVTTVVSS", "down_seq": "PSVVMSTVAQGVSTSAIKVA", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr323", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BMB0-1.465.465", "start_pos": 465, "end_pos": 465, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SNSPIMVVSSNGAIMTTKLV", "down_seq": "TPTGTQATYTRPTVSPSLGR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr465", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GlcNAc) threonine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr465", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.466.466", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.470.470", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.466.466", "start_pos": 466, "end_pos": 466, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NSPIMVVSSNGAIMTTKLVT", "down_seq": "PTGTQATYTRPTVSPSLGRV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr466", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.465.465", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.470.470", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.470.470", "start_pos": 470, "end_pos": 470, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MVVSSNGAIMTTKLVTTPTG", "down_seq": "QATYTRPTVSPSLGRVATTP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GlcNAc) threonine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.465.465", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.466.466", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BMB0-1.489.489", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.489.489", "start_pos": 489, "end_pos": 489, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GTQATYTRPTVSPSLGRVAT", "down_seq": "PGAATYVKTTSGSIITVVPK", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr489", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BMB0-1.470.470", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BMB0-1.498.498", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.499.499", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.500.500", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BMB0-1.498.498", "start_pos": 498, "end_pos": 498, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TVSPSLGRVATTPGAATYVK", "down_seq": "TSGSIITVVPKSLATLGGKI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8BMB0-1.489.489", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.499.499", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.500.500", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.499.499", "start_pos": 499, "end_pos": 499, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Chalkley RJ, Thalhammer A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "19458039", "url": "https://glygen.org/publication/PubMed/19458039" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "19458039", "url": "https://glygen.org/publication/PubMed/19458039", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VSPSLGRVATTPGAATYVKT", "down_seq": "SGSIITVVPKSLATLGGKII", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr499", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "19458039", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19458039" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.489.489", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.498.498", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.500.500", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.500.500", "start_pos": 500, "end_pos": 500, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPSLGRVATTPGAATYVKTT", "down_seq": "GSIITVVPKSLATLGGKIIS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser500", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.489.489", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.498.498", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.499.499", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.505.505", "start_pos": 505, "end_pos": 505, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RVATTPGAATYVKTTSGSII", "down_seq": "VVPKSLATLGGKIISSNIVS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr505", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BMB0-1.489.489", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8BMB0-1.498.498", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.499.499", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.500.500", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.510.510", "start_pos": 510, "end_pos": 510, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance.", "journal": "Cancer cell", "date": "2022-10-10", "authors": "Shi Qingzhu, Shen Qicong, Liu Yanfang, Shi Yang, Huang Wenwen, Wang Xi, Li Zhiqing, Chai Yangyang, Wang Hao, Hu Xiangjia, Li Nan, Zhang Qian, Cao Xuetao", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36084651", "url": "https://glygen.org/publication/PubMed/36084651" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36084651", "url": "https://glygen.org/publication/PubMed/36084651", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PGAATYVKTTSGSIITVVPK", "down_seq": "LATLGGKIISSNIVSGTTTK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser510", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36084651", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36084651" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8BMB0-1.498.498", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.499.499", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.500.500", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BMB0-1.529.529", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.520.520", "start_pos": 520, "end_pos": 520, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SGSIITVVPKSLATLGGKII", "down_seq": "SNIVSGTTTKITTIPMTSKP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser520", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8BMB0-1.500.500", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BMB0-1.529.529", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8BMB0-1.533.533", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8BMB0-1.538.538", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.521.521", "start_pos": 521, "end_pos": 521, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases", "journal": "Front Aging", "date": "2021", "authors": "Huynh V.N., Wang S., Ouyang X., Wani W.Y., Johnson M.S., Chacko B.K., Jegga A.G., Qian W.J., Chatham J.C., Darley-Usmar V.M., Zhang J.", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "DOI", "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801", "database": "DOI", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GSIITVVPKSLATLGGKIIS", "down_seq": "NIVSGTTTKITTIPMTSKPN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser521", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "10.3389/fragi.2021.757801", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser521", "evidence": [ { "id": "Q8BMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.529.529", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8BMB0-1.533.533", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8BMB0-1.538.538", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.525.525", "start_pos": 525, "end_pos": 525, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TVVPKSLATLGGKIISSNIV", "down_seq": "GTTTKITTIPMTSKPNVIVV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser525", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8BMB0-1.505.505", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.529.529", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.533.533", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8BMB0-1.538.538", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.529.529", "start_pos": 529, "end_pos": 529, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KSLATLGGKIISSNIVSGTT", "down_seq": "KITTIPMTSKPNVIVVQKTT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr529", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BMB0-1.510.510", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.533.533", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BMB0-1.538.538", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.533.533", "start_pos": 533, "end_pos": 533, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TLGGKIISSNIVSGTTTKIT", "down_seq": "IPMTSKPNVIVVQKTTGKGT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr533", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.529.529", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BMB0-1.538.538", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.538.538", "start_pos": 538, "end_pos": 538, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IISSNIVSGTTTKITTIPMT", "down_seq": "KPNVIVVQKTTGKGTTIQGL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser538", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8BMB0-1.520.520", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q8BMB0-1.521.521", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8BMB0-1.525.525", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8BMB0-1.529.529", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BMB0-1.533.533", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.818.818", "start_pos": 818, "end_pos": 818, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EYITTVSHRSQPQQPSQPQR", "down_seq": "LLQHVAQSQTATQTSVVVKS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr818", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q8BMB0-1.826.826", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.826.826", "start_pos": 826, "end_pos": 826, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://oglcnac.org/atlas/detail/Q8BMB0", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RSQPQQPSQPQRTLLQHVAQ", "down_seq": "QTATQTSVVVKSIPASSPGA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser826", "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q8BMB0", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.818.818", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8BMB0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8BMB0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.1085.1085", "start_pos": 1085, "end_pos": 1085, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTKITGGSSVPKLTSPVTSI", "down_seq": "PIQASEKTAVSDILQMSLME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "site_lbl": "Ser1085" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BMB0-1.1069.1069", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BMB0-1.171.171", "start_pos": 171, "end_pos": 171, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ASKDGVSCSDEDEKPRKRRR", "down_seq": "NSSSSSPVVLKEVPKAVVPV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "site_lbl": "Thr171" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q8BMB0-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BMB0-1.177.177", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BMB0-1.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KDGVSCSDEDEKPRKRRRTN", "down_seq": "SSSSPVVLKEVPKAVVPVSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "site_lbl": "Ser173" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BMB0-1.177.177", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BMB0-1.192.192", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.177.177", "start_pos": 177, "end_pos": 177, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SCSDEDEKPRKRRRTNSSSS", "down_seq": "PVVLKEVPKAVVPVSKTITV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "site_lbl": "Ser177" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.171.171", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BMB0-1.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8BMB0-1.192.192", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8BMB0-1.194.194", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BMB0-1.196.196", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.202.202", "start_pos": 202, "end_pos": 202, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KEVPKAVVPVSKTITVPVSG", "down_seq": "PKMSNIMQSIANSLPPHMSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "site_lbl": "Ser202" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8BMB0-1.192.192", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BMB0-1.194.194", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BMB0-1.196.196", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BMB0-1.200.200", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BMB0-1.782.782", "start_pos": 782, "end_pos": 782, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTIDLSQMAVPIQMTQEKRH", "down_seq": "PESPSIAVVESELVAEYITT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "site_lbl": "Ser782" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8BMB0-1.785.785", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BMB0-1.785.785", "start_pos": 785, "end_pos": 785, "uniprot_canonical_ac": "Q8BMB0-1", "length": 1264, "uniprot_id": "EMSY_MOUSE", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "refseq_ac": "NP_758484", "refseq_name": "BRCA2-interacting transcriptional repressor EMSY isoform 4", "gene_name": "Emsy", "gene_names_uniprotkb": "Emsy", "gene_names_refseq": "2210018M11Rik; 2310016L09Rik; Emsy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLSQMAVPIQMTQEKRHSPE", "down_seq": "PSIAVVESELVAEYITTVSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8BMB0", "url": "https://www.uniprot.org/uniprotkb/Q8BMB0" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8BMB0", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8BMB0" } ], "site_lbl": "Ser785" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "1039", "end_pos": "1039" }, { "start_pos": "1047", "end_pos": "1047" }, { "start_pos": "1069", "end_pos": "1069" }, { "start_pos": "1176", "end_pos": "1176" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "200", "end_pos": "200" }, { "start_pos": "226", "end_pos": "226" }, { "start_pos": "228", "end_pos": "228" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "232", "end_pos": "232" }, { "start_pos": "234", "end_pos": "234" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "236", "end_pos": "236" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "247", "end_pos": "247" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "323", "end_pos": "323" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "466", "end_pos": "466" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "489", "end_pos": "489" }, { "start_pos": "498", "end_pos": "498" }, { "start_pos": "499", "end_pos": "499" }, { "start_pos": "500", "end_pos": "500" }, { "start_pos": "505", "end_pos": "505" }, { "start_pos": "510", "end_pos": "510" }, { "start_pos": "520", "end_pos": "520" }, { "start_pos": "521", "end_pos": "521" }, { "start_pos": "525", "end_pos": "525" }, { "start_pos": "529", "end_pos": "529" }, { "start_pos": "533", "end_pos": "533" }, { "start_pos": "538", "end_pos": "538" }, { "start_pos": "818", "end_pos": "818" }, { "start_pos": "826", "end_pos": "826" } ] }, { "type": "snv", "site_list": [ { "start_pos": "192", "end_pos": "192" }, { "start_pos": "231", "end_pos": "231" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1085", "end_pos": "1085" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "177", "end_pos": "177" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "782", "end_pos": "782" }, { "start_pos": "785", "end_pos": "785" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8BMB0-1.782.782", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.1656.1656", "start_pos": 1656, "end_pos": 1656, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AMAVGEPGLASKPASPAAGP", "down_seq": "QEEKSRLLKERLDQIHFINE", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1656", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.1646.1646", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.1650.1650", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.2168.2168", "start_pos": 2168, "end_pos": 2168, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EYVYEDADGQTEVMPLWTPP", "down_seq": "PPQDDNDIYIDSVMCLMYET", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2168", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.2532.2532", "start_pos": 2532, "end_pos": 2532, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PQPQVQTQPQPVQPQSKGQP", "down_seq": "MTTVGSAAVLAGTIKTSVTG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2532", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2535.2535", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2538.2538", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.2551.2551", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2535.2535", "start_pos": 2535, "end_pos": 2535, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QVQTQPQPVQPQSKGQPTMT", "down_seq": "VGSAAVLAGTIKTSVTGTSI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2535", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2532.2532", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2538.2538", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.2551.2551", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.2554.2554", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2538.2538", "start_pos": 2538, "end_pos": 2538, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TQPQPVQPQSKGQPTMTTVG", "down_seq": "AAVLAGTIKTSVTGTSIPTG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2538", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2532.2532", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2535.2535", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.2551.2551", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.2554.2554", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2551.2551", "start_pos": 2551, "end_pos": 2551, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PTMTTVGSAAVLAGTIKTSV", "down_seq": "GTSIPTGTVSGNVIVNTIAG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2551", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.2532.2532", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.2535.2535", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.2538.2538", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2554.2554", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2554.2554", "start_pos": 2554, "end_pos": 2554, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTVGSAAVLAGTIKTSVTGT", "down_seq": "IPTGTVSGNVIVNTIAGVPA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2554", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.2535.2535", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.2538.2538", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2551.2551", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2586.2586", "start_pos": 2586, "end_pos": 2586, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VNTIAGVPAATFQSINKRLA", "down_seq": "PVAPGTLTTSGGSAPAQVVH", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2586", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2592.2592", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2594.2594", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.2595.2595", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2596.2596", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2592.2592", "start_pos": 2592, "end_pos": 2592, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VPAATFQSINKRLASPVAPG", "down_seq": "LTTSGGSAPAQVVHTQQRAV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2592", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2586.2586", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2594.2594", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2595.2595", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.2596.2596", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2594.2594", "start_pos": 2594, "end_pos": 2594, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AATFQSINKRLASPVAPGTL", "down_seq": "TSGGSAPAQVVHTQQRAVGS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2594", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2586.2586", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2592.2592", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.2595.2595", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2596.2596", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2595.2595", "start_pos": 2595, "end_pos": 2595, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATFQSINKRLASPVAPGTLT", "down_seq": "SGGSAPAQVVHTQQRAVGSP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2595", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.2586.2586", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2592.2592", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.2594.2594", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.2596.2596", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2596.2596", "start_pos": 2596, "end_pos": 2596, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TFQSINKRLASPVAPGTLTT", "down_seq": "GGSAPAQVVHTQQRAVGSPA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2596", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2586.2586", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.2592.2592", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2594.2594", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.2595.2595", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2599.2599", "start_pos": 2599, "end_pos": 2599, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SINKRLASPVAPGTLTTSGG", "down_seq": "APAQVVHTQQRAVGSPATAT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2599", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.2586.2586", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.2592.2592", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.2594.2594", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.2595.2595", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2596.2596", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2614.2614", "start_pos": 2614, "end_pos": 2614, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TTSGGSAPAQVVHTQQRAVG", "down_seq": "PATATTDLVSMTTTQGVRAV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2614", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "site_lbl": "Ser2614" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8CHI8-1.2594.2594", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.2595.2595", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2596.2596", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2617.2617", "start_pos": 2617, "end_pos": 2617, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GGSAPAQVVHTQQRAVGSPA", "down_seq": "ATTDLVSMTTTQGVRAVTSV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2617", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2599.2599", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2620.2620", "start_pos": 2620, "end_pos": 2620, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APAQVVHTQQRAVGSPATAT", "down_seq": "DLVSMTTTQGVRAVTSVTAS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2620", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2624.2624", "start_pos": 2624, "end_pos": 2624, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVHTQQRAVGSPATATTDLV", "down_seq": "MTTTQGVRAVTSVTASAVVT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2624", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2626.2626", "start_pos": 2626, "end_pos": 2626, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HTQQRAVGSPATATTDLVSM", "down_seq": "TTQGVRAVTSVTASAVVTTN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2626", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8CHI8-1.2614.2614", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2635.2635", "start_pos": 2635, "end_pos": 2635, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PATATTDLVSMTTTQGVRAV", "down_seq": "SVTASAVVTTNLTPVQTPTR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2635", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2636.2636", "start_pos": 2636, "end_pos": 2636, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ATATTDLVSMTTTQGVRAVT", "down_seq": "VTASAVVTTNLTPVQTPTRS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2636", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.2617.2617", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2638.2638", "start_pos": 2638, "end_pos": 2638, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ATTDLVSMTTTQGVRAVTSV", "down_seq": "ASAVVTTNLTPVQTPTRSLV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2638", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2620.2620", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2644.2644", "start_pos": 2644, "end_pos": 2644, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SMTTTQGVRAVTSVTASAVV", "down_seq": "TNLTPVQTPTRSLVTQVSQA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2644", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8CHI8-1.2624.2624", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2645.2645", "start_pos": 2645, "end_pos": 2645, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MTTTQGVRAVTSVTASAVVT", "down_seq": "NLTPVQTPTRSLVTQVSQAT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2645", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2646.2646", "start_pos": 2646, "end_pos": 2646, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TTTQGVRAVTSVTASAVVTT", "down_seq": "LTPVQTPTRSLVTQVSQATG", "glycosylation": [ { "glytoucan_ac": "G36703TD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "AVTSVTASAVVTTNLTPVQTPTR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2646", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8CHI8-1.2626.2626", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2648.2648", "start_pos": 2648, "end_pos": 2648, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TQGVRAVTSVTASAVVTTNL", "down_seq": "PVQTPTRSLVTQVSQATGVQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2648", "evidence": [ { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2652.2652", "start_pos": 2652, "end_pos": 2652, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RAVTSVTASAVVTTNLTPVQ", "down_seq": "PTRSLVTQVSQATGVQLPGK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2652", "evidence": [ { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2654.2654", "start_pos": 2654, "end_pos": 2654, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke.", "journal": "Redox biology", "date": "2024-08", "authors": "Guo Haiyun, Li Yumeng, Wang Shiquan, Yang Yongheng, Xu Tiantian, Zhao Jianshuai, Wang Jin, Zuo Wenqiang, Wang Pengju, Zhao Guangchao, Wang Huaning, Hou Wugang, Dong Hailong, Cai Yanhui", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834" } ] } ], "crossref": [ { "id": "38861834", "url": "https://glygen.org/publication/PubMed/38861834", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VTSVTASAVVTTNLTPVQTP", "down_seq": "RSLVTQVSQATGVQLPGKTI", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2654", "evidence": [ { "id": "38861834", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/38861834" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.2635.2635", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2656.2656", "start_pos": 2656, "end_pos": 2656, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SVTASAVVTTNLTPVQTPTR", "down_seq": "LVTQVSQATGVQLPGKTITP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2656", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8CHI8-1.2636.2636", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2638.2638", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2659.2659", "start_pos": 2659, "end_pos": 2659, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ASAVVTTNLTPVQTPTRSLV", "down_seq": "QVSQATGVQLPGKTITPAAH", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2659", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2662.2662", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2662.2662", "start_pos": 2662, "end_pos": 2662, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases", "journal": "Front Aging", "date": "2021", "authors": "Huynh V.N., Wang S., Ouyang X., Wani W.Y., Johnson M.S., Chacko B.K., Jegga A.G., Qian W.J., Chatham J.C., Darley-Usmar V.M., Zhang J.", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "DOI", "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801", "database": "DOI", "categories": [ "Other" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VVTTNLTPVQTPTRSLVTQV", "down_seq": "QATGVQLPGKTITPAAHFQL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2662", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "10.3389/fragi.2021.757801", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.2644.2644", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q8CHI8-1.2645.2645", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.2646.2646", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.2648.2648", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.2652.2652", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2654.2654", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.2656.2656", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2659.2659", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2863.2863", "start_pos": 2863, "end_pos": 2863, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VTTLPMNVAGISVAIGQPQK", "down_seq": "AGQTVVAQPVNVQQLLKYKQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2863", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2932.2932", "start_pos": 2932, "end_pos": 2932, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QITTQGPQQKVAYAAQPALK", "down_seq": "QFLTTPISQAQKLAGTQQVQ", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2932", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.2937.2937", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.2940.2940", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2937.2937", "start_pos": 2937, "end_pos": 2937, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GPQQKVAYAAQPALKTQFLT", "down_seq": "PISQAQKLAGTQQVQTQIQV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2937", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.2932.2932", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.2940.2940", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.2940.2940", "start_pos": 2940, "end_pos": 2940, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] }, { "title": "Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2018", "authors": "Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092" } ] }, { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases", "journal": "Front Aging", "date": "2021", "authors": "Huynh V.N., Wang S., Ouyang X., Wani W.Y., Johnson M.S., Chacko B.K., Jegga A.G., Qian W.J., Chatham J.C., Darley-Usmar V.M., Zhang J.", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "DOI", "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29237092", "url": "https://glygen.org/publication/PubMed/29237092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10.3389/fragi.2021.757801", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801", "database": "DOI", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QKVAYAAQPALKTQFLTTPI", "down_seq": "QAQKLAGTQQVQTQIQVAKL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2940", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "29237092", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29237092" }, { "id": "10.3389/fragi.2021.757801", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.3389/fragi.2021.757801" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.2932.2932", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.2937.2937", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.3024.3024", "start_pos": 3024, "end_pos": 3024, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PTVTATAQLVQQKLIQQQVV", "down_seq": "TASASLQTPGGPSPAQLPAS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3024", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.320.320", "start_pos": 320, "end_pos": 320, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VLLPGVGGPSAFGMTSPPPP", "down_seq": "SPSRTTMPPGLSSVPLTSMG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.315.315", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.321.321", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.554.554", "start_pos": 554, "end_pos": 554, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VNAGVPLQQLMPTVQGGMPP", "down_seq": "PQATQLTGQKQSQQQYDPST", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr554", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.630.630", "start_pos": 630, "end_pos": 630, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QFSQQSQMVEASTQLQIPVK", "down_seq": "QQLNAPIPAPLPSQLPAPSS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr630", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.643.643", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.643.643", "start_pos": 643, "end_pos": 643, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QLQIPVKTQQLNAPIPAPLP", "down_seq": "QLPAPSSQPAQPALHVPMPG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser643", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.630.630", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.695.695", "start_pos": 695, "end_pos": 695, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QTQTVASTRPPLDSAQPCQR", "down_seq": "LPTSSSSSSLVPVSGSGPGP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser695", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.698.698", "start_pos": 698, "end_pos": 698, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TVASTRPPLDSAQPCQRSLP", "down_seq": "SSSSSSLVPVSGSGPGPSPA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr698", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.699.699", "start_pos": 699, "end_pos": 699, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VASTRPPLDSAQPCQRSLPT", "down_seq": "SSSSSLVPVSGSGPGPSPAR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser699", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.700.700", "start_pos": 700, "end_pos": 700, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASTRPPLDSAQPCQRSLPTS", "down_seq": "SSSSLVPVSGSGPGPSPARS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser700", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.702.702", "start_pos": 702, "end_pos": 702, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TRPPLDSAQPCQRSLPTSSS", "down_seq": "SSLVPVSGSGPGPSPARSSP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser702", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.703.703", "start_pos": 703, "end_pos": 703, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RPPLDSAQPCQRSLPTSSSS", "down_seq": "SLVPVSGSGPGPSPARSSPV", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser703", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.704.704", "start_pos": 704, "end_pos": 704, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPLDSAQPCQRSLPTSSSSS", "down_seq": "LVPVSGSGPGPSPARSSPVN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser704", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.709.709", "start_pos": 709, "end_pos": 709, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AQPCQRSLPTSSSSSSLVPV", "down_seq": "GSGPGPSPARSSPVNRPSSA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser709", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.695.695", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.716.716", "start_pos": 716, "end_pos": 716, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Myers SA, Panning B, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21606357", "url": "https://glygen.org/publication/PubMed/21606357", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LPTSSSSSSLVPVSGSGPGP", "down_seq": "PARSSPVNRPSSATNKALSP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser716", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "21606357", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21606357" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.698.698", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q8CHI8-1.699.699", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8CHI8-1.700.700", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.702.702", "categories": [ "glycosylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.703.703", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8CHI8-1.704.704", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q8CHI8-1.709.709", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.735.735", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.954.954", "start_pos": 954, "end_pos": 954, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" }, { "database": "O-GlcNAc Atlas", "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://oglcnac.org/atlas/detail/Q8CHI8", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GRKRKASTSLTDDEVEDEEE", "down_seq": "IEEEEAHEGLVDHHTELTNL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr954", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q8CHI8", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8CHI8-1.940.940", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8CHI8-1.944.944", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] } ], "crossref": [ { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "Q8CHI8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CHI8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.171.171", "start_pos": 171, "end_pos": 171, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs247479822", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs247479822", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "AGAPGPGLGICSNSPTGGFV", "down_seq": "ASVLVRQISLSPSSGGHFVF", "snv": [ { "evidence": [ { "id": "rs247479822", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs247479822" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DAS->NAS).", "chr_id": "5", "chr_pos": "110904087", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D171", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.1009.1009", "start_pos": 1009, "end_pos": 1009, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YEGAFLPNFQWPQPEPDHEE", "down_seq": "SGEEDVEDCPSDRESRRDSV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser1009" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.1010.1010", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.1010.1010", "start_pos": 1010, "end_pos": 1010, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EGAFLPNFQWPQPEPDHEES", "down_seq": "GEEDVEDCPSDRESRRDSVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser1010" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.1009.1009", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.134.134", "start_pos": 134, "end_pos": 134, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HGSPSYIQVTSPMSQQVQTQ", "down_seq": "PTQPSPGPGQTLQNVRAGAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser134" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.1646.1646", "start_pos": 1646, "end_pos": 1646, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VGVPGRVAVSAMAVGEPGLA", "down_seq": "KPASPAAGPTQEEKSRLLKE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "site_lbl": "Ser1646" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.1650.1650", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.1656.1656", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.1650.1650", "start_pos": 1650, "end_pos": 1650, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRVAVSAMAVGEPGLASKPA", "down_seq": "PAAGPTQEEKSRLLKERLDQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "site_lbl": "Ser1650" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.1646.1646", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.1656.1656", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ERTPGVLLPGVGGPSAFGMT", "down_seq": "PPPPTSPSRTTMPPGLSSVP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser315" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.320.320", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.321.321", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLPGVGGPSAFGMTSPPPPT", "down_seq": "PSRTTMPPGLSSVPLTSMGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser321" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.315.315", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.320.320", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.52.52", "start_pos": 52, "end_pos": 52, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NLPPSPAAPFAPSASPSAPQ", "down_seq": "PGYQIQQLMSRSPVAGQNVN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser52" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.735.735", "start_pos": 735, "end_pos": 735, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSPARSSPVNRPSSATNKAL", "down_seq": "PITSRSPGVAVSAPPKPQSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "site_lbl": "Ser735" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.716.716", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8CHI8-1.741.741", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8CHI8-1.754.754", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CHI8-1.741.741", "start_pos": 741, "end_pos": 741, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPVNRPSSATNKALSPITSR", "down_seq": "PGVAVSAPPKPQSPAQNAAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser741" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8CHI8-1.735.735", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.754.754", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.754.754", "start_pos": 754, "end_pos": 754, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSPITSRSPGVAVSAPPKPQ", "down_seq": "PAQNAASSQDGSQDKLAEQI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser754" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8CHI8-1.735.735", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.741.741", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.922.922", "start_pos": 922, "end_pos": 922, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ALNLQKVSRRGKESRLKGFD", "down_seq": "SPEHSLDLGISGRKRKASTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Thr922" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8CHI8-1.923.923", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8CHI8-1.927.927", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8CHI8-1.940.940", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.923.923", "start_pos": 923, "end_pos": 923, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LNLQKVSRRGKESRLKGFDT", "down_seq": "PEHSLDLGISGRKRKASTSL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser923" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8CHI8-1.922.922", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.927.927", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8CHI8-1.940.940", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.927.927", "start_pos": 927, "end_pos": 927, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KVSRRGKESRLKGFDTSPEH", "down_seq": "LDLGISGRKRKASTSLTDDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser927" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8CHI8-1.922.922", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.923.923", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8CHI8-1.940.940", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8CHI8-1.944.944", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.940.940", "start_pos": 940, "end_pos": 940, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FDTSPEHSLDLGISGRKRKA", "down_seq": "TSLTDDEVEDEEETIEEEEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Ser940" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8CHI8-1.922.922", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q8CHI8-1.923.923", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8CHI8-1.927.927", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8CHI8-1.944.944", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8CHI8-1.954.954", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CHI8-1.944.944", "start_pos": 944, "end_pos": 944, "uniprot_canonical_ac": "Q8CHI8-1", "length": 3072, "uniprot_id": "EP400_MOUSE", "protein_name": "E1A-binding protein p400", "refseq_ac": "NP_083613", "refseq_name": "E1A-binding protein p400 isoform 1", "gene_name": "Ep400", "gene_names_uniprotkb": "Ep400; Kiaa1498", "gene_names_refseq": "1700020J09Rik; Ep400; mDomino; mKIAA1498; p400", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PEHSLDLGISGRKRKASTSL", "down_seq": "DDEVEDEEETIEEEEAHEGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8CHI8", "url": "https://www.uniprot.org/uniprotkb/Q8CHI8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CHI8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CHI8" } ], "site_lbl": "Thr944" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1656", "end_pos": "1656" }, { "start_pos": "2168", "end_pos": "2168" }, { "start_pos": "2532", "end_pos": "2532" }, { "start_pos": "2535", "end_pos": "2535" }, { "start_pos": "2538", "end_pos": "2538" }, { "start_pos": "2551", "end_pos": "2551" }, { "start_pos": "2554", "end_pos": "2554" }, { "start_pos": "2586", "end_pos": "2586" }, { "start_pos": "2592", "end_pos": "2592" }, { "start_pos": "2594", "end_pos": "2594" }, { "start_pos": "2595", "end_pos": "2595" }, { "start_pos": "2596", "end_pos": "2596" }, { "start_pos": "2599", "end_pos": "2599" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "2617", "end_pos": "2617" }, { "start_pos": "2620", "end_pos": "2620" }, { "start_pos": "2624", "end_pos": "2624" }, { "start_pos": "2626", "end_pos": "2626" }, { "start_pos": "2635", "end_pos": "2635" }, { "start_pos": "2636", "end_pos": "2636" }, { "start_pos": "2638", "end_pos": "2638" }, { "start_pos": "2644", "end_pos": "2644" }, { "start_pos": "2645", "end_pos": "2645" }, { "start_pos": "2646", "end_pos": "2646" }, { "start_pos": "2648", "end_pos": "2648" }, { "start_pos": "2652", "end_pos": "2652" }, { "start_pos": "2654", "end_pos": "2654" }, { "start_pos": "2656", "end_pos": "2656" }, { "start_pos": "2659", "end_pos": "2659" }, { "start_pos": "2662", "end_pos": "2662" }, { "start_pos": "2863", "end_pos": "2863" }, { "start_pos": "2932", "end_pos": "2932" }, { "start_pos": "2937", "end_pos": "2937" }, { "start_pos": "2940", "end_pos": "2940" }, { "start_pos": "3024", "end_pos": "3024" }, { "start_pos": "320", "end_pos": "320" }, { "start_pos": "554", "end_pos": "554" }, { "start_pos": "630", "end_pos": "630" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "695", "end_pos": "695" }, { "start_pos": "698", "end_pos": "698" }, { "start_pos": "699", "end_pos": "699" }, { "start_pos": "700", "end_pos": "700" }, { "start_pos": "702", "end_pos": "702" }, { "start_pos": "703", "end_pos": "703" }, { "start_pos": "704", "end_pos": "704" }, { "start_pos": "709", "end_pos": "709" }, { "start_pos": "716", "end_pos": "716" }, { "start_pos": "954", "end_pos": "954" } ] }, { "type": "snv", "site_list": [ { "start_pos": "171", "end_pos": "171" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1010", "end_pos": "1010" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "1646", "end_pos": "1646" }, { "start_pos": "1650", "end_pos": "1650" }, { "start_pos": "2614", "end_pos": "2614" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "52", "end_pos": "52" }, { "start_pos": "735", "end_pos": "735" }, { "start_pos": "741", "end_pos": "741" }, { "start_pos": "754", "end_pos": "754" }, { "start_pos": "922", "end_pos": "922" }, { "start_pos": "923", "end_pos": "923" }, { "start_pos": "927", "end_pos": "927" }, { "start_pos": "940", "end_pos": "940" }, { "start_pos": "944", "end_pos": "944" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8CHI8-1.927.927", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8CHI8-1.940.940", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8CHI8-1.954.954", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.146.146", "start_pos": 146, "end_pos": 146, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "EKSASPKRIDFIPVSPAPSP", "down_seq": "RGIGKQCFSPSLQSFVSSNG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr146", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "site_lbl": "Thr146" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9DB52-1.140.140", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9DB52-1.144.144", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DB52-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IHGLSDSSPVFQAEAPSARR", "down_seq": "STTFPSRHGLLLPASPVRMH", "glycosylation": [ { "glytoucan_ac": "G41071NU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "RNSTTFPSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn58", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9DB52-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q9DB52-1.45.45", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9DB52-1.59.59", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q9DB52-1.73.73", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.140.140", "start_pos": 140, "end_pos": 140, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSDNDVEKSASPKRIDFIPV", "down_seq": "PAPSPTRGIGKQCFSPSLQS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser140" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9DB52-1.144.144", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9DB52-1.146.146", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.144.144", "start_pos": 144, "end_pos": 144, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DVEKSASPKRIDFIPVSPAP", "down_seq": "PTRGIGKQCFSPSLQSFVSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser144" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9DB52-1.140.140", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9DB52-1.146.146", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNGLPPSPIPSPTTRFTTRR", "down_seq": "QSPINCIRPSVLGPLKRKCE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "site_lbl": "Ser184" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q9DB52-1.186.186", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DB52-1.186.186", "start_pos": 186, "end_pos": 186, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLPPSPIPSPTTRFTTRRSQ", "down_seq": "PINCIRPSVLGPLKRKCEME", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "site_lbl": "Ser186" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9DB52-1.184.184", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DB52-1.264.264", "start_pos": 264, "end_pos": 264, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NSSSAGSSCNSPAKVSTTTD", "down_seq": "PVSPAQAASPFIPVDELSSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser264" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q9DB52-1.267.267", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9DB52-1.273.273", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.267.267", "start_pos": 267, "end_pos": 267, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SAGSSCNSPAKVSTTTDSPV", "down_seq": "PAQAASPFIPVDELSSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser267" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9DB52-1.264.264", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9DB52-1.273.273", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.273.273", "start_pos": 273, "end_pos": 273, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NSPAKVSTTTDSPVSPAQAA", "down_seq": "PFIPVDELSSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser273" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q9DB52-1.264.264", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q9DB52-1.267.267", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.32.32", "start_pos": 32, "end_pos": 32, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LPAGASPAEGGGPGGGGLRR", "down_seq": "NSAPLIHGLSDSSPVFQAEA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "site_lbl": "Ser32" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q9DB52-1.34.34", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q9DB52-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q9DB52-1.45.45", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DB52-1.34.34", "start_pos": 34, "end_pos": 34, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGASPAEGGGPGGGGLRRSN", "down_seq": "APLIHGLSDSSPVFQAEAPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CHEK1", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "site_lbl": "Ser34" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9DB52-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9DB52-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9DB52-1.45.45", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DB52-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGPGGGGLRRSNSAPLIHGL", "down_seq": "DSSPVFQAEAPSARRNSTTF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "site_lbl": "Ser42" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q9DB52-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q9DB52-1.34.34", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9DB52-1.45.45", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9DB52-1.58.58", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9DB52-1.59.59", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DB52-1.45.45", "start_pos": 45, "end_pos": 45, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGGGLRRSNSAPLIHGLSDS", "down_seq": "PVFQAEAPSARRNSTTFPSR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser45" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q9DB52-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q9DB52-1.34.34", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9DB52-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q9DB52-1.58.58", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9DB52-1.59.59", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.59.59", "start_pos": 59, "end_pos": 59, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HGLSDSSPVFQAEAPSARRN", "down_seq": "TTFPSRHGLLLPASPVRMHS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser59" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9DB52-1.42.42", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q9DB52-1.45.45", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9DB52-1.58.58", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9DB52-1.73.73", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DB52-1.73.73", "start_pos": 73, "end_pos": 73, "uniprot_canonical_ac": "Q9DB52-1", "length": 284, "uniprot_id": "PBIR1_MOUSE", "protein_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "refseq_ac": "NP_080796", "refseq_name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "gene_name": "Pabir1", "gene_names_uniprotkb": "Pabir1; Fam122a", "gene_names_refseq": "2410124L17Rik; 2900009I07Rik; Fam122a; Gm9849; Pabir1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] } ], "crossref": [ { "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSARRNSTTFPSRHGLLLPA", "down_seq": "PVRMHSSRLHQIKQEEGMDL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DB52", "url": "https://www.uniprot.org/uniprotkb/Q9DB52" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "iPTMnet", "id": "Q9DB52", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DB52" } ], "site_lbl": "Ser73" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "146", "end_pos": "146" }, { "start_pos": "58", "end_pos": "58" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "140", "end_pos": "140" }, { "start_pos": "144", "end_pos": "144" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "264", "end_pos": "264" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "59", "end_pos": "59" }, { "start_pos": "73", "end_pos": "73" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q9DB52-1.58.58", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q9DB52-1.59.59", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.168.168", "start_pos": 168, "end_pos": 168, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "IKKKHSNKQEMGTYLRFIVS", "down_seq": "MKERAIDLNKKGKDSKHPMY", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Impaired H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.234.236", "start_pos": 234, "end_pos": 236, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "DSE", "start_aa": "D", "up_seq": "EEFKADAQLLLHNTVIFYGA", "down_seq": "QADIARMLYKDTCHELDELQ", "mutagenesis": [ { "sequence_org": "DSE", "sequence_mut": "ASA", "comment": "No effect on protein folding and histone binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "Q8R5C8-1.251.251", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.251.251", "start_pos": 251, "end_pos": 251, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "YGADSEQADIARMLYKDTCH", "down_seq": "LDELQLCKNCFYLSNARPDN", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Impaired H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8R5C8-1.234.236", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8R5C8-1.266.266", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.266.266", "start_pos": 266, "end_pos": 266, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KDTCHELDELQLCKNCFYLS", "down_seq": "ARPDNWFCYPCIPNHELVWA", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "A", "comment": "Impaired H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8R5C8-1.251.251", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "NWFCYPCIPNHELVWAKMKG", "down_seq": "GFWPAKVMQKEDNQVDVRFF", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abolished H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8R5C8-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8R5C8-1.307.307", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8R5C8-1.310.310", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.294.294", "start_pos": 294, "end_pos": 294, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "CYPCIPNHELVWAKMKGFGF", "down_seq": "PAKVMQKEDNQVDVRFFGHH", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Abolished H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8R5C8-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8R5C8-1.307.307", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8R5C8-1.310.310", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.307.307", "start_pos": 307, "end_pos": 307, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "KMKGFGFWPAKVMQKEDNQV", "down_seq": "VRFFGHHHQRAWIPSENIQD", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Impaired H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8R5C8-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8R5C8-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8R5C8-1.310.310", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.310.310", "start_pos": 310, "end_pos": 310, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.", "journal": "Nature", "date": "2014", "authors": "Wen H, Li Y, Xi Y, Jiang S, Stratton S, Peng D, Tanaka K, Ren Y, Xia Z, Wu J, Li B, Barton MC, Li W, Li H, Shi X", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "reference": [ { "type": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "GFGFWPAKVMQKEDNQVDVR", "down_seq": "FGHHHQRAWIPSENIQDITV", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "A", "comment": "Abolished H3.3K36me3 binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" }, { "database": "PubMed", "id": "24590075", "url": "https://glygen.org/publication/PubMed/24590075" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8R5C8-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8R5C8-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8R5C8-1.307.307", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R5C8-1.421.421", "start_pos": 421, "end_pos": 421, "uniprot_canonical_ac": "Q8R5C8-1", "length": 602, "uniprot_id": "ZMY11_MOUSE", "protein_name": "Zinc finger MYND domain-containing protein 11", "refseq_ac": "NP_001186070", "refseq_name": "zinc finger MYND domain-containing protein 11 isoform gamma", "gene_name": "Zmynd11", "gene_names_uniprotkb": "Zmynd11", "gene_names_refseq": "2210402G22Rik; BS69; Zmynd11", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NQSVEPKKEEPEPETEAVSS", "down_seq": "QEIPTMPQPIERVSVSTQTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R5C8", "url": "https://www.uniprot.org/uniprotkb/Q8R5C8" } ], "site_lbl": "Ser421" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "168", "end_pos": "168" }, { "start_pos": "234", "end_pos": "236" }, { "start_pos": "251", "end_pos": "251" }, { "start_pos": "266", "end_pos": "266" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "310", "end_pos": "310" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "421", "end_pos": "421" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P10649-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P10649-1", "length": 218, "uniprot_id": "GSTM1_MOUSE", "protein_name": "Glutathione S-transferase Mu 1", "refseq_ac": "NP_034488", "refseq_name": "glutathione S-transferase Mu 1 isoform 2", "gene_name": "Gstm1", "gene_names_uniprotkb": "Gstm1", "gene_names_refseq": "Gstb-1; Gstb1; Gstm1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P10649", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P10649", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "P10649", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P10649", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P10649", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P10649", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "P10649", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10649" }, { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "210", "end_pos": "210" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "67", "end_pos": "67" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P10649-1.210.210", "start_pos": 210, "end_pos": 210, "uniprot_canonical_ac": "P10649-1", "length": 218, "uniprot_id": "GSTM1_MOUSE", "protein_name": "Glutathione S-transferase Mu 1", "refseq_ac": "NP_034488", "refseq_name": "glutathione S-transferase Mu 1 isoform 2", "gene_name": "Gstm1", "gene_names_uniprotkb": "Gstm1", "gene_names_refseq": "Gstb-1; Gstb1; Gstm1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GLKKISAYMKSSRYIATPIF", "down_seq": "KMAHWSNK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" } ], "site_lbl": "Ser210" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "210", "end_pos": "210" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "67", "end_pos": "67" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P10649-1.34.34", "start_pos": 34, "end_pos": 34, "uniprot_canonical_ac": "P10649-1", "length": 218, "uniprot_id": "GSTM1_MOUSE", "protein_name": "Glutathione S-transferase Mu 1", "refseq_ac": "NP_034488", "refseq_name": "glutathione S-transferase Mu 1 isoform 2", "gene_name": "Gstm1", "gene_names_uniprotkb": "Gstm1", "gene_names_refseq": "Gstb-1; Gstb1; Gstm1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" }, { "database": "iPTMnet", "id": "P10649", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10649" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P10649", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10649", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "THPIRMLLEYTDSSYDEKRY", "down_seq": "MGDAPDFDRSQWLNEKFKLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P10649", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10649" } ], "site_lbl": "Thr34" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "210", "end_pos": "210" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "67", "end_pos": "67" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P10649-1.67.67", "start_pos": 67, "end_pos": 67, "uniprot_canonical_ac": "P10649-1", "length": 218, "uniprot_id": "GSTM1_MOUSE", "protein_name": "Glutathione S-transferase Mu 1", "refseq_ac": "NP_034488", "refseq_name": "glutathione S-transferase Mu 1 isoform 2", "gene_name": "Gstm1", "gene_names_uniprotkb": "Gstm1", "gene_names_refseq": "Gstb-1; Gstb1; Gstm1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LNEKFKLGLDFPNLPYLIDG", "down_seq": "HKITQSNAILRYLARKHHLD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P10649", "url": "https://www.uniprot.org/uniprotkb/P10649" } ], "site_lbl": "Ser67" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "210", "end_pos": "210" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "67", "end_pos": "67" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ESZ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ESZ8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9ESZ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ESZ8" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESZ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ESZ8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "Q9ESZ8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9ESZ8" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "Q9ESZ8-1.19.19", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESZ8-1.103.103", "start_pos": 103, "end_pos": 103, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEEKAAEMHKMKSTTQANRM", "down_seq": "VDAVEIETLRKTVEDYFCFC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser103" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.19.19", "start_pos": 19, "end_pos": 19, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MAQVVMSALPAEDEESSE", "down_seq": "RMVVTFLMSALESMCKELAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser19" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9ESZ8-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFLEPKKHLGGRVLAAEAER", "down_seq": "MLSPSGSCGPIKVKTEPTED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser207" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q9ESZ8-1.210.210", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9ESZ8-1.214.214", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.210.210", "start_pos": 210, "end_pos": 210, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPKKHLGGRVLAAEAERSML", "down_seq": "PSGSCGPIKVKTEPTEDSGI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser210" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9ESZ8-1.207.207", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9ESZ8-1.214.214", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HLGGRVLAAEAERSMLSPSG", "down_seq": "CGPIKVKTEPTEDSGISLEM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser214" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q9ESZ8-1.207.207", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9ESZ8-1.210.210", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "JAK2 activates TFII-I and regulates its interaction with extracellular signal-regulated kinase.", "journal": "Molecular and cellular biology", "date": "2001", "authors": "Kim DW, Cochran BH", "evidence": [ { "database": "iPTMnet", "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8" } ], "reference": [ { "type": "PubMed", "id": "11313464", "url": "https://glygen.org/publication/PubMed/11313464" } ] } ], "crossref": [ { "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11313464", "url": "https://glygen.org/publication/PubMed/11313464", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SGISLEMAAVTVKEESEDPD", "down_seq": "YQYNIQGPSETDGVDEKLPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "Q62120-1", "kinase_gene_name": "Jak2", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8" }, { "database": "PubMed", "id": "11313464", "url": "https://glygen.org/publication/PubMed/11313464" } ], "site_lbl": "Tyr248" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by BTK", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Tyr248" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESZ8-1.398.398", "start_pos": 398, "end_pos": 398, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KAKGPVTIPYPLFQSHVEDL", "down_seq": "VEGLPEGIPFRRPSTYGIPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by BTK", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Tyr398" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "Q9ESZ8-1.412.412", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.412.412", "start_pos": 412, "end_pos": 412, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SHVEDLYVEGLPEGIPFRRP", "down_seq": "TYGIPRLERILLAKERIRFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKG/PRKG1", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser412" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9ESZ8-1.398.398", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.503.503", "start_pos": 503, "end_pos": 503, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GSTEAKAVPYQKFEAHPNDL", "down_seq": "VEGLPENIPFRSPSWYGIPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by BTK", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Tyr503" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "Q9ESZ8-1.517.517", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.517.517", "start_pos": 517, "end_pos": 517, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AHPNDLYVEGLPENIPFRSP", "down_seq": "WYGIPRLEKIIQVGNRIKFV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser517" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9ESZ8-1.503.503", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.556.556", "start_pos": 556, "end_pos": 556, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" }, { "database": "iPTMnet", "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FVIKRPELLTHSTTEVTQPR", "down_seq": "NTPVKEDWNVRITKLRKQVE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8" } ], "site_lbl": "Thr556" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q9ESZ8-1.558.558", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESZ8-1.558.558", "start_pos": 558, "end_pos": 558, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" }, { "database": "iPTMnet", "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IKRPELLTHSTTEVTQPRTN", "down_seq": "PVKEDWNVRITKLRKQVEEI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9ESZ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9ESZ8" } ], "site_lbl": "Thr558" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q9ESZ8-1.556.556", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9ESZ8-1.668.668", "start_pos": 668, "end_pos": 668, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LVVSYLPPGMASKINTKALQ", "down_seq": "PKRPRSPGSNSKVPEIEVTV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser668" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q9ESZ8-1.674.674", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.674.674", "start_pos": 674, "end_pos": 674, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPGMASKINTKALQSPKRPR", "down_seq": "PGSNSKVPEIEVTVEGPNNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser674" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9ESZ8-1.668.668", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.722.722", "start_pos": 722, "end_pos": 722, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RTPTQTNGSNVPFKPRGREF", "down_seq": "FEAWNAKITDLKQKVENLFN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser722" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.784.784", "start_pos": 784, "end_pos": 784, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SFPEDFYVEGLPEGVPFRRP", "down_seq": "TFGIPRLEKILRNKAKIKFI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKG/PRKG1", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser784" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9ESZ8-1.823.823", "start_pos": 823, "end_pos": 823, "uniprot_canonical_ac": "Q9ESZ8-1", "length": 998, "uniprot_id": "GTF2I_MOUSE", "protein_name": "General transcription factor II-I", "refseq_ac": "NP_001074215", "refseq_name": "general transcription factor II-I isoform 1", "gene_name": "Gtf2i", "gene_names_uniprotkb": "Gtf2i; Bap135; Diws1t", "gene_names_refseq": "6030441I21Rik; BAP-135; Diws1t; Gtf2i; GtfII-I; Spin; TFII-I; WBSCR6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FIIKKPEMFETAIKESTSSK", "down_seq": "PPRKINSSPNVNTTASGVED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9ESZ8", "url": "https://www.uniprot.org/uniprotkb/Q9ESZ8" } ], "site_lbl": "Ser823" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "103", "end_pos": "103" }, { "start_pos": "19", "end_pos": "19" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "503", "end_pos": "503" }, { "start_pos": "517", "end_pos": "517" }, { "start_pos": "556", "end_pos": "556" }, { "start_pos": "558", "end_pos": "558" }, { "start_pos": "668", "end_pos": "668" }, { "start_pos": "674", "end_pos": "674" }, { "start_pos": "722", "end_pos": "722" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "823", "end_pos": "823" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.283.283", "start_pos": 283, "end_pos": 283, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KDKKKKTKKIKEKYIDQEEL", "down_seq": "KTKPIWTRNPDDITQEEYGE", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YIDQEELNK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn283", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "upstream", "id": "P11499-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P11499-1.301.301", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.389.389", "start_pos": 389, "end_pos": 389, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LIPEYLNFIRGVVDSEDLPL", "down_seq": "ISREMLQQSKILKVIRKNIV", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GVVDSEDLPLNISR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn389", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.434.434", "start_pos": 434, "end_pos": 434, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.", "journal": "PloS one", "date": "2014", "authors": "Gurel Z, Zaro BW, Pratt MR, Sheibani N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Overath T, Kuckelkorn U, Henklein P, Strehl B, Bonar D, Kloss A, Siele D, Kloetzel PM, Janek K", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499#ptm_processing" }, { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" }, { "database": "O-GlcNAc Atlas", "id": "P11499", "url": "https://oglcnac.org/atlas/detail/P11499" } ], "reference": [ { "type": "PubMed", "id": "22556278", "url": "https://glygen.org/publication/PubMed/22556278" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22556278", "url": "https://glygen.org/publication/PubMed/22556278", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "https://oglcnac.org/atlas/detail/P11499", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELFSELAEDKENYKKFYEAF", "down_seq": "KNLKLGIHEDSTNRRRLSEL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser434", "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P11499", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" }, { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "24788674", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24788674" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "22556278", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22556278" }, { "id": "P11499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P11499" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser434", "evidence": [ { "id": "P11499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11499#ptm_processing" }, { "id": "22556278", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22556278" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P11499-1.445.445", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P11499-1.452.452", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.452.452", "start_pos": 452, "end_pos": 452, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.", "journal": "PloS one", "date": "2014", "authors": "Gurel Z, Zaro BW, Pratt MR, Sheibani N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Overath T, Kuckelkorn U, Henklein P, Strehl B, Bonar D, Kloss A, Siele D, Kloetzel PM, Janek K", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499#ptm_processing" }, { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" }, { "database": "O-GlcNAc Atlas", "id": "P11499", "url": "https://oglcnac.org/atlas/detail/P11499" } ], "reference": [ { "type": "PubMed", "id": "22556278", "url": "https://glygen.org/publication/PubMed/22556278" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22556278", "url": "https://glygen.org/publication/PubMed/22556278", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "https://oglcnac.org/atlas/detail/P11499", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AFSKNLKLGIHEDSTNRRRL", "down_seq": "ELLRYHTSQSGDEMTSLSEY", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser452", "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P11499", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" }, { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "24788674", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24788674" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "22556278", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22556278" }, { "id": "P11499", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P11499" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser452", "evidence": [ { "id": "P11499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11499#ptm_processing" }, { "id": "22556278", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22556278" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P11499-1.434.434", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P11499-1.445.445", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P11499-1.462.462", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.462.462", "start_pos": 462, "end_pos": 462, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.", "journal": "PloS one", "date": "2014", "authors": "Gurel Z, Zaro BW, Pratt MR, Sheibani N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "Mapping of O-GlcNAc sites of 20 S proteasome subunits and Hsp90 by a novel biotin-cystamine tag.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Overath T, Kuckelkorn U, Henklein P, Strehl B, Bonar D, Kloss A, Siele D, Kloetzel PM, Janek K", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499#ptm_processing" }, { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" }, { "database": "O-GlcNAc Atlas", "id": "P11499", "url": "https://oglcnac.org/atlas/detail/P11499" } ], "reference": [ { "type": "PubMed", "id": "22556278", "url": "https://glygen.org/publication/PubMed/22556278" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22556278", "url": "https://glygen.org/publication/PubMed/22556278", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HEDSTNRRRLSELLRYHTSQ", "down_seq": "GDEMTSLSEYVSRMKETQKS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser462", "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P11499", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" }, { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "24788674", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24788674" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "22556278", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22556278" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P11499-1.445.445", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P11499-1.452.452", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P11499-1.479.479", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.614.614", "start_pos": 614, "end_pos": 614, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "STYGWTANMERIMKAQALRD", "down_seq": "STMGYMMAKKHLEINPDHPI", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DNSTMGYMMAK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn614", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P11499", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11499" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.226.226", "start_pos": 226, "end_pos": 226, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SQFIGYPITLYLEKEREKEI", "down_seq": "DDEAEEEKGEKEEEDKEDEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "site_lbl": "Ser226" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.", "journal": "Journal of proteome research", "date": "2007", "authors": "Smith JC, Duchesne MA, Tozzi P, Ethier M, Figeys D", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.", "journal": "Molecular & cellular proteomics : MCP", "date": "2007", "authors": "Lee J, Xu Y, Chen Y, Sprung R, Kim SC, Xie S, Zhao Y", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "17208939", "url": "https://glygen.org/publication/PubMed/17208939" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.", "journal": "Journal of proteome research", "date": "2008", "authors": "Zhou H, Ye M, Dong J, Han G, Jiang X, Wu R, Zou H", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17208939", "url": "https://glygen.org/publication/PubMed/17208939", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GEKEEEDKEDEEKPKIEDVG", "down_seq": "DEEDDSGKDKKKKTKKIKEK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "17208939", "url": "https://glygen.org/publication/PubMed/17208939" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "site_lbl": "Ser255" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P11499-1.261.261", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.261.261", "start_pos": 261, "end_pos": 261, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.", "journal": "Journal of proteome research", "date": "2007", "authors": "Smith JC, Duchesne MA, Tozzi P, Ethier M, Figeys D", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" } ] } ], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKEDEEKPKIEDVGSDEEDD", "down_seq": "GKDKKKKTKKIKEKYIDQEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "site_lbl": "Ser261" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P11499-1.255.255", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.297.297", "start_pos": 297, "end_pos": 297, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IDQEELNKTKPIWTRNPDDI", "down_seq": "QEEYGEFYKSLTNDWEDHLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Thr297" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P11499-1.283.283", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P11499-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P11499-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P11499-1.307.307", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.301.301", "start_pos": 301, "end_pos": 301, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ELNKTKPIWTRNPDDITQEE", "down_seq": "GEFYKSLTNDWEDHLAVKHF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Tyr301" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P11499-1.283.283", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P11499-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P11499-1.305.305", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P11499-1.307.307", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.305.305", "start_pos": 305, "end_pos": 305, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] } ], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "TKPIWTRNPDDITQEEYGEF", "down_seq": "KSLTNDWEDHLAVKHFSVEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "site_lbl": "Tyr305" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P11499-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P11499-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P11499-1.307.307", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.307.307", "start_pos": 307, "end_pos": 307, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PIWTRNPDDITQEEYGEFYK", "down_seq": "LTNDWEDHLAVKHFSVEGQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Ser307" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P11499-1.297.297", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P11499-1.301.301", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P11499-1.305.305", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.445.445", "start_pos": 445, "end_pos": 445, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NYKKFYEAFSKNLKLGIHED", "down_seq": "TNRRRLSELLRYHTSQSGDE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Ser445" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P11499-1.434.434", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P11499-1.452.452", "categories": [ "glycosylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P11499-1.462.462", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.479.479", "start_pos": 479, "end_pos": 479, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TSQSGDEMTSLSEYVSRMKE", "down_seq": "QKSIYYITGESKEQVANSAF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Thr479" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P11499-1.462.462", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P11499-1.484.484", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.484.484", "start_pos": 484, "end_pos": 484, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Cao L, Yu K, Banh C, Nguyen V, Ritz A, Raphael BJ, Kawakami Y, Kawakami T, Salomon AR", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "reference": [ { "type": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" } ] } ], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "DEMTSLSEYVSRMKETQKSI", "down_seq": "YITGESKEQVANSAFVERVR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" }, { "database": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" }, { "database": "iPTMnet", "id": "P11499", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11499" } ], "site_lbl": "Tyr484" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P11499-1.479.479", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11499-1.669.669", "start_pos": 669, "end_pos": 669, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KAVKDLVVLLFETALLSSGF", "down_seq": "LEDPQTHSNRIYRMIKLGLG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Ser669" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11499-1.718.718", "start_pos": 718, "end_pos": 718, "uniprot_canonical_ac": "P11499-1", "length": 724, "uniprot_id": "HS90B_MOUSE", "protein_name": "Heat shock protein HSP 90-beta", "refseq_ac": "NP_032328", "refseq_name": "heat shock protein HSP 90-beta", "gene_name": "Hsp90ab1", "gene_names_uniprotkb": "Hsp90ab1; Hsp84-1; Hsp84; Hspc3; Hspcb", "gene_names_refseq": "90kDa; Hsp84-1; Hsp84; Hsp90ab1; Hsp90; Hspcb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEPSAAVPDEIPPLEGDEDA", "down_seq": "RMEEVD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PLK2 and PLK3", "evidence": [ { "database": "UniProtKB", "id": "P11499", "url": "https://www.uniprot.org/uniprotkb/P11499" } ], "site_lbl": "Ser718" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "283", "end_pos": "283" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "434", "end_pos": "434" }, { "start_pos": "452", "end_pos": "452" }, { "start_pos": "462", "end_pos": "462" }, { "start_pos": "614", "end_pos": "614" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "226", "end_pos": "226" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "301", "end_pos": "301" }, { "start_pos": "305", "end_pos": "305" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "484", "end_pos": "484" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "718", "end_pos": "718" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9QXE0-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9QXE0-1", "length": 581, "uniprot_id": "HACL1_MOUSE", "protein_name": "2-hydroxyacyl-CoA lyase 1", "refseq_ac": "NP_064359", "refseq_name": "2-hydroxyacyl-CoA lyase 1", "gene_name": "Hacl1", "gene_names_uniprotkb": "Hacl1; Hpcl; Phyh2", "gene_names_refseq": "1600020H07Rik; Hacl1; Hpcl; Phyh2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9QXE0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QXE0" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QXE0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QXE0", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q9QXE0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QXE0" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "4", "end_pos": "4" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9QXE0-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9QXE0-1.6.6", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QXE0-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "Q9QXE0-1", "length": 581, "uniprot_id": "HACL1_MOUSE", "protein_name": "2-hydroxyacyl-CoA lyase 1", "refseq_ac": "NP_064359", "refseq_name": "2-hydroxyacyl-CoA lyase 1", "gene_name": "Hacl1", "gene_names_uniprotkb": "Hacl1; Hpcl; Phyh2", "gene_names_refseq": "1600020H07Rik; Hacl1; Hpcl; Phyh2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPE", "down_seq": "NSAEGSDRSEEQVSGAKVIA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0" } ], "site_lbl": "Ser4" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "4", "end_pos": "4" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9QXE0-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9QXE0-1.6.6", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9QXE0-1.6.6", "start_pos": 6, "end_pos": 6, "uniprot_canonical_ac": "Q9QXE0-1", "length": 581, "uniprot_id": "HACL1_MOUSE", "protein_name": "2-hydroxyacyl-CoA lyase 1", "refseq_ac": "NP_064359", "refseq_name": "2-hydroxyacyl-CoA lyase 1", "gene_name": "Hacl1", "gene_names_uniprotkb": "Hacl1; Hpcl; Phyh2", "gene_names_refseq": "1600020H07Rik; Hacl1; Hpcl; Phyh2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPESN", "down_seq": "AEGSDRSEEQVSGAKVIAQA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QXE0", "url": "https://www.uniprot.org/uniprotkb/Q9QXE0" } ], "site_lbl": "Ser6" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "4", "end_pos": "4" }, { "start_pos": "6", "end_pos": "6" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9QXE0-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9QXE0-1.4.4", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DAI6-1.985.985", "start_pos": 985, "end_pos": 985, "uniprot_canonical_ac": "Q9DAI6-1", "length": 1403, "uniprot_id": "F135B_MOUSE", "protein_name": "Protein FAM135B", "refseq_ac": "NP_808487", "refseq_name": "protein FAM135B", "gene_name": "Fam135b", "gene_names_uniprotkb": "Fam135b", "gene_names_refseq": "1700010C24Rik; A830008O07Rik; Fam135b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" }, { "database": "O-GlcNAc Atlas", "id": "Q9DAI6", "url": "https://oglcnac.org/atlas/detail/Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LNRRHNASLEAKHEAGTVCP", "down_seq": "VTHTIASQVSRNQELKTGTS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr985", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q9DAI6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "985", "end_pos": "985" }, { "start_pos": "989", "end_pos": "989" } ] }, { "type": "snv", "site_list": [ { "start_pos": "806", "end_pos": "806" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "775", "end_pos": "775" }, { "start_pos": "776", "end_pos": "776" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9DAI6-1.989.989", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DAI6-1.989.989", "start_pos": 989, "end_pos": 989, "uniprot_canonical_ac": "Q9DAI6-1", "length": 1403, "uniprot_id": "F135B_MOUSE", "protein_name": "Protein FAM135B", "refseq_ac": "NP_808487", "refseq_name": "protein FAM135B", "gene_name": "Fam135b", "gene_names_uniprotkb": "Fam135b", "gene_names_refseq": "1700010C24Rik; A830008O07Rik; Fam135b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" }, { "database": "O-GlcNAc Atlas", "id": "Q9DAI6", "url": "https://oglcnac.org/atlas/detail/Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q9DAI6", "url": "https://oglcnac.org/atlas/detail/Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DAI6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DAI6", "url": "https://oglcnac.org/atlas/detail/Q9DAI6", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "HNASLEAKHEAGTVCPTVTH", "down_seq": "IASQVSRNQELKTGTSISGS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr989", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q9DAI6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9DAI6" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q9DAI6", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q9DAI6" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "985", "end_pos": "985" }, { "start_pos": "989", "end_pos": "989" } ] }, { "type": "snv", "site_list": [ { "start_pos": "806", "end_pos": "806" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "775", "end_pos": "775" }, { "start_pos": "776", "end_pos": "776" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9DAI6-1.985.985", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DAI6-1.806.806", "start_pos": 806, "end_pos": 806, "uniprot_canonical_ac": "Q9DAI6-1", "length": 1403, "uniprot_id": "F135B_MOUSE", "protein_name": "Protein FAM135B", "refseq_ac": "NP_808487", "refseq_name": "protein FAM135B", "gene_name": "Fam135b", "gene_names_uniprotkb": "Fam135b", "gene_names_refseq": "1700010C24Rik; A830008O07Rik; Fam135b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs260446440", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs260446440", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "TIKNTAGFSEDLDPSSKENS", "down_seq": "PRHTSLSYGGSRVQDVRAGH", "snv": [ { "evidence": [ { "id": "rs260446440", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs260446440" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NSP->NSS).", "chr_id": "15", "chr_pos": "71334777", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P806", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "985", "end_pos": "985" }, { "start_pos": "989", "end_pos": "989" } ] }, { "type": "snv", "site_list": [ { "start_pos": "806", "end_pos": "806" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "775", "end_pos": "775" }, { "start_pos": "776", "end_pos": "776" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9DAI6-1.775.775", "start_pos": 775, "end_pos": 775, "uniprot_canonical_ac": "Q9DAI6-1", "length": 1403, "uniprot_id": "F135B_MOUSE", "protein_name": "Protein FAM135B", "refseq_ac": "NP_808487", "refseq_name": "protein FAM135B", "gene_name": "Fam135b", "gene_names_uniprotkb": "Fam135b", "gene_names_refseq": "1700010C24Rik; A830008O07Rik; Fam135b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" }, { "database": "iPTMnet", "id": "Q9DAI6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DAI6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DAI6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EEERELALNKLTKSVSAPQI", "down_seq": "SPEESAEGADTIKNTAGFSE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9DAI6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DAI6" } ], "site_lbl": "Ser775" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "985", "end_pos": "985" }, { "start_pos": "989", "end_pos": "989" } ] }, { "type": "snv", "site_list": [ { "start_pos": "806", "end_pos": "806" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "775", "end_pos": "775" }, { "start_pos": "776", "end_pos": "776" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9DAI6-1.776.776", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9DAI6-1.776.776", "start_pos": 776, "end_pos": 776, "uniprot_canonical_ac": "Q9DAI6-1", "length": 1403, "uniprot_id": "F135B_MOUSE", "protein_name": "Protein FAM135B", "refseq_ac": "NP_808487", "refseq_name": "protein FAM135B", "gene_name": "Fam135b", "gene_names_uniprotkb": "Fam135b", "gene_names_refseq": "1700010C24Rik; A830008O07Rik; Fam135b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" }, { "database": "iPTMnet", "id": "Q9DAI6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DAI6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9DAI6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DAI6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EERELALNKLTKSVSAPQIS", "down_seq": "PEESAEGADTIKNTAGFSED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9DAI6", "url": "https://www.uniprot.org/uniprotkb/Q9DAI6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9DAI6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9DAI6" } ], "site_lbl": "Ser776" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "985", "end_pos": "985" }, { "start_pos": "989", "end_pos": "989" } ] }, { "type": "snv", "site_list": [ { "start_pos": "806", "end_pos": "806" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "775", "end_pos": "775" }, { "start_pos": "776", "end_pos": "776" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9DAI6-1.775.775", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9D8T2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9D8T2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D8T2", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q9D8T2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D8T2" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "Q9D8T2-1.7.14", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9D8T2-1.17.20", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.105.105", "start_pos": 105, "end_pos": 105, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.", "journal": "Nature", "date": "2015", "authors": "Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, Cuellar T, Haley B, Roose-Girma M, Phung QT, Liu PS, Lill JR, Li H, Wu J, Kummerfeld S, Zhang J, Lee WP, Snipas SJ, Salvesen GS, Morris LX, Fitzgerald L, Zhang Y, Bertram EM, Goodnow CC, Dixit VM", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259" } ] }, { "title": "Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.", "journal": "Structure (London, England : 1993)", "date": "2018", "authors": "Liu Z, Wang C, Rathkey JK, Yang J, Dubyak GR, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "29576317", "url": "https://glygen.org/publication/PubMed/29576317" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29576317", "url": "https://glygen.org/publication/PubMed/29576317", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "DVVDGNIQGRVMLSGMGEGK", "down_seq": "SGGAAVSDSSSASMNVCILR", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "N", "comment": "Reduced ability to induce pyroptosis. No effect on protein expression. No effect on cleavage by CASP4.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259" }, { "database": "PubMed", "id": "29576317", "url": "https://glygen.org/publication/PubMed/29576317" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9D8T2-1.85.88", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q9D8T2-1.95.95", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9D8T2-1.122.122", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.122.122", "start_pos": 122, "end_pos": 122, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "EGKISGGAAVSDSSSASMNV", "down_seq": "ILRVTQKTWETMQHERHLQQ", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect on oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9D8T2-1.105.105", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9D8T2-1.138.138", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.138.138", "start_pos": 138, "end_pos": 138, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "SMNVCILRVTQKTWETMQHE", "down_seq": "HLQQPENKILQQLRSRGDDL", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Complete loss of homooligomerization, lipid-binding, relocalization of Gasdermin-D, N-terminal to the plasma membrane and pyroptosis, as well as loss of bactericidal activity; when associated with A-146; A-152 and A-154. Partial loss of homooligomerization and pyroptosis; when associated with A-146.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] }, { "sequence_org": "R", "sequence_mut": "S", "comment": "Complete loss of homooligomerization, lipid-binding, relocalization of Gasdermin-D, N-terminal to the plasma membrane and pyroptosis, as well as loss of bactericidal activity; when associated with A-146; A-152 and A-154. Partial loss of homooligomerization and pyroptosis; when associated with A-146.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9D8T2-1.122.122", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9D8T2-1.146.146", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9D8T2-1.154.154", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.146.146", "start_pos": 146, "end_pos": 146, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "VTQKTWETMQHERHLQQPEN", "down_seq": "ILQQLRSRGDDLFVVTEVLQ", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Complete loss of homooligomerization, lipid-binding, relocalization of Gasdermin-D, N-terminal to the plasma membrane and pyroptosis, as well as loss of bactericidal activity; when associated with A-138 or with S-138; A-152 and A-154. Partial loss of homooligomerization and pyroptosis; when associated with A-138, with A-152 or with A-152 and A-154.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q9D8T2-1.138.138", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9D8T2-1.152.152", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9D8T2-1.154.154", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "ETMQHERHLQQPENKILQQL", "down_seq": "SRGDDLFVVTEVLQTKEEVQ", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Complete loss of homooligomerization, lipid-binding, relocalization of Gasdermin-D, N-terminal to the plasma membrane and pyroptosis, as well as loss of bactericidal activity; when associated with A-138 or with S-138; A-146 and A-154. Partial loss of homooligomerization and pyroptosis; when associated with A-146 or with A-154, or with A-146 and A-154.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.138.138", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q9D8T2-1.146.146", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9D8T2-1.154.154", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.154.154", "start_pos": 154, "end_pos": 154, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "MQHERHLQQPENKILQQLRS", "down_seq": "GDDLFVVTEVLQTKEEVQIT", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Complete loss of homooligomerization, lipid-binding, relocalization of Gasdermin-D, N-terminal to the plasma membrane and pyroptosis, as well as loss of bactericidal activity; when associated with A-138 or with S-138; A-146 and A-152. Partial loss of homooligomerization and pyroptosis; when associated with A-152 or with A-146 and A-152.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9D8T2-1.138.138", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q9D8T2-1.146.146", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9D8T2-1.152.152", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.17.20", "start_pos": 17, "end_pos": 20, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8.", "journal": "Nature communications", "date": "2023-01-04", "authors": "Yin Hang, Zheng Jian, He Qiuqiu, Zhang Xuan, Li Xuzichao, Ma Yongjian, Liang Xiao, Gao Jiaqi, Kocsis Benjamin L, Li Zhuang, Liu Xiang, Alto Neal M, Li Long, Zhang Heng", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "36599845", "url": "https://glygen.org/publication/PubMed/36599845" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "36599845", "url": "https://glygen.org/publication/PubMed/36599845", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "SGSR", "start_aa": "S", "up_seq": "MPSAFEKVVKNVIKEV", "down_seq": "GDLIPVDSLRNSTSFRPYCL", "mutagenesis": [ { "sequence_org": "SGSR", "sequence_mut": "DGS", "comment": "Renders Gsdmd susceptible to ubiquitination by S.flexneri IpaH7.8.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "36599845", "url": "https://glygen.org/publication/PubMed/36599845" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9D8T2-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9D8T2-1.7.14", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9D8T2-1.29.29", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9D8T2-1.38.38", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q9D8T2-1.39.39", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.192.192", "start_pos": 192, "end_pos": 192, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] }, { "title": "Succination inactivates gasdermin D and blocks pyroptosis.", "journal": "Science (New York, N.Y.)", "date": "2020", "authors": "Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "32820063", "url": "https://glygen.org/publication/PubMed/32820063" } ] }, { "title": "A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis.", "journal": "Nature cell biology", "date": "2024-05", "authors": "Zhang Na, Zhang Jian, Yang Yuanxin, Shan Hengyue, Hou Shouqiao, Fang Hongwen, Ma Min, Chen Zhongwen, Tan Li, Xu Daichao", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834" } ] }, { "title": "The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis.", "journal": "Science immunology", "date": "2024-04-12", "authors": "Balasubramanian Arumugam, Hsu Alan Y, Ghimire Laxman, Tahir Muhammad, Devant Pascal, Fontana Pietro, Du Gang, Liu Xing, Fabin Dang, Kambara Hiroto, Xie Xuemei, Liu Fei, Hasegawa Tomoya, Xu Rong, Yu Hongbo, Chen Mei, Kolakowski Steven, Trauger Sunia, Larsen Martin R\u00f8ssel, Wei Wenyi, Wu Hao, Kagan Jonathan C, Lieberman Judy, Luo Hongbo R", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "38530158", "url": "https://glygen.org/publication/PubMed/38530158" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32820063", "url": "https://glygen.org/publication/PubMed/32820063", "database": "PubMed", "categories": [ "Other" ] }, { "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834", "database": "PubMed", "categories": [ "Other" ] }, { "id": "38530158", "url": "https://glygen.org/publication/PubMed/38530158", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "QITEVHSQEGSGQFTLPGAL", "down_seq": "LKGEGKGHQSRKKMVTIPAG", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of oligomerization of Gasdermin-D, N-terminal. Abolished palmitoylation and ability to form a pore and mediate pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" }, { "database": "PubMed", "id": "32820063", "url": "https://glygen.org/publication/PubMed/32820063" }, { "database": "PubMed", "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834" }, { "database": "PubMed", "id": "38530158", "url": "https://glygen.org/publication/PubMed/38530158" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9D8T2-1.193.193", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.193.193", "start_pos": 193, "end_pos": 193, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "ITEVHSQEGSGQFTLPGALC", "down_seq": "KGEGKGHQSRKKMVTIPAGS", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9D8T2-1.192.192", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.230.233", "start_pos": 230, "end_pos": 233, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "ILLV", "start_aa": "I", "up_seq": "PAGSILAFRVAQLLIGSKWD", "down_seq": "SDEKQRTFEPSSGDRKAVGQ", "mutagenesis": [ { "sequence_org": "ILLV", "sequence_mut": "ALLA", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.237.237", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9D8T2-1.239.239", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q9D8T2-1.248.248", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9D8T2-1.249.249", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.237.237", "start_pos": 237, "end_pos": 237, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "FRVAQLLIGSKWDILLVSDE", "down_seq": "QRTFEPSSGDRKAVGQRHHG", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on pyroptosis; when associated with A-239 or with A-239; A-248 and A-249.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.230.233", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q9D8T2-1.239.239", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9D8T2-1.248.248", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q9D8T2-1.249.249", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.239.239", "start_pos": 239, "end_pos": 239, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "VAQLLIGSKWDILLVSDEKQ", "down_seq": "TFEPSSGDRKAVGQRHHGLN", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on pyroptosis; when associated with A-237 or with A-237; A-248 and A-249.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9D8T2-1.230.233", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q9D8T2-1.237.237", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9D8T2-1.248.248", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q9D8T2-1.249.249", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "WDILLVSDEKQRTFEPSSGD", "down_seq": "KAVGQRHHGLNVLAALCSIG", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on pyroptosis; when associated with A-237; A-239 and A-249.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q9D8T2-1.230.233", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q9D8T2-1.237.237", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q9D8T2-1.239.239", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9D8T2-1.249.249", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9D8T2-1.265.265", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.249.249", "start_pos": 249, "end_pos": 249, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "DILLVSDEKQRTFEPSSGDR", "down_seq": "AVGQRHHGLNVLAALCSIGK", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on pyroptosis; when associated with A-237; A-239 and A-248.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q9D8T2-1.230.233", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q9D8T2-1.237.237", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q9D8T2-1.239.239", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9D8T2-1.248.248", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9D8T2-1.265.265", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.265.265", "start_pos": 265, "end_pos": 265, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "SGDRKAVGQRHHGLNVLAAL", "down_seq": "SIGKQLSLLSDGIDEEELIE", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect on oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9D8T2-1.248.248", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q9D8T2-1.249.249", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9D8T2-1.273.273", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9D8T2-1.276.276", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.273.273", "start_pos": 273, "end_pos": 273, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.", "journal": "Immunity", "date": "2020", "authors": "Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "QRHHGLNVLAALCSIGKQLS", "down_seq": "LSDGIDEEELIEAADFQGLY", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Impaired interaction and cleavage by CASP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q9D8T2-1.265.265", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9D8T2-1.276.276", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q9D8T2-1.292.292", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.276.276", "start_pos": 276, "end_pos": 276, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.", "journal": "Nature", "date": "2015", "authors": "Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, Cuellar T, Haley B, Roose-Girma M, Phung QT, Liu PS, Lill JR, Li H, Wu J, Kummerfeld S, Zhang J, Lee WP, Snipas SJ, Salvesen GS, Morris LX, Fitzgerald L, Zhang Y, Bertram EM, Goodnow CC, Dixit VM", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259" } ] }, { "title": "Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion.", "journal": "Cell research", "date": "2015", "authors": "He WT, Wan H, Hu L, Chen P, Wang X, Huang Z, Yang ZH, Zhong CQ, Han J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "26611636", "url": "https://glygen.org/publication/PubMed/26611636" } ] }, { "title": "Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.", "journal": "Science (New York, N.Y.)", "date": "2018", "authors": "Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "30361383", "url": "https://glygen.org/publication/PubMed/30361383" } ] }, { "title": "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.", "journal": "Immunity", "date": "2020", "authors": "Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] }, { "title": "Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation.", "journal": "The Journal of experimental medicine", "date": "2018-09-03", "authors": "Lee Bettina L, Stowe Irma B, Gupta Aaron, Kornfeld Opher S, Roose-Girma Merone, Anderson Keith, Warming S\u00f8ren, Zhang Juan, Lee Wyne P, Kayagaki Nobuhiko", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "30135078", "url": "https://glygen.org/publication/PubMed/30135078" } ] }, { "title": "A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis.", "journal": "Nature cell biology", "date": "2024-05", "authors": "Zhang Na, Zhang Jian, Yang Yuanxin, Shan Hengyue, Hou Shouqiao, Fang Hongwen, Ma Min, Chen Zhongwen, Tan Li, Xu Daichao", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26611636", "url": "https://glygen.org/publication/PubMed/26611636", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30361383", "url": "https://glygen.org/publication/PubMed/30361383", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30135078", "url": "https://glygen.org/publication/PubMed/30135078", "database": "PubMed", "categories": [ "Other" ] }, { "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "HGLNVLAALCSIGKQLSLLS", "down_seq": "GIDEEELIEAADFQGLYAEV", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of CASP1-induced cleavage, pyroptosis and IL1B release. Does not impair interaction with CASP1. Loss of CASP4/CASP11-induced cleavage. Abolished ability to induce pyroptosis following inactivation of MAP3K7/TAK1 by Yersinia toxin YopJ.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259" }, { "database": "PubMed", "id": "26611636", "url": "https://glygen.org/publication/PubMed/26611636" }, { "database": "PubMed", "id": "30361383", "url": "https://glygen.org/publication/PubMed/30361383" }, { "database": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" }, { "database": "PubMed", "id": "30135078", "url": "https://glygen.org/publication/PubMed/30135078" }, { "database": "PubMed", "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834" } ] }, { "sequence_org": "D", "sequence_mut": "N", "comment": "Loss of CASP1-induced cleavage, pyroptosis and IL1B release. Does not impair interaction with CASP1. Loss of CASP4/CASP11-induced cleavage. Abolished ability to induce pyroptosis following inactivation of MAP3K7/TAK1 by Yersinia toxin YopJ.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "26375259", "url": "https://glygen.org/publication/PubMed/26375259" }, { "database": "PubMed", "id": "26611636", "url": "https://glygen.org/publication/PubMed/26611636" }, { "database": "PubMed", "id": "30361383", "url": "https://glygen.org/publication/PubMed/30361383" }, { "database": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" }, { "database": "PubMed", "id": "30135078", "url": "https://glygen.org/publication/PubMed/30135078" }, { "database": "PubMed", "id": "38538834", "url": "https://glygen.org/publication/PubMed/38538834" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q9D8T2-1.265.265", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9D8T2-1.273.273", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q9D8T2-1.292.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q9D8T2-1.295.295", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "SLLSDGIDEEELIEAADFQG", "down_seq": "YAEVKACSSELESLEMELRQ", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "D", "comment": "Disrupts intramolecular interactions and autoinhibition, leading to spontaneous pyroptosis-inducing activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9D8T2-1.273.273", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q9D8T2-1.276.276", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9D8T2-1.295.295", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.306.310", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9D8T2-1.309.313", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.295.295", "start_pos": 295, "end_pos": 295, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "SDGIDEEELIEAADFQGLYA", "down_seq": "VKACSSELESLEMELRQQIL", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "R", "comment": "Disrupts intramolecular interactions and autoinhibition, leading to spontaneous pyroptosis-inducing activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9D8T2-1.276.276", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9D8T2-1.292.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9D8T2-1.306.310", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.309.313", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.29.29", "start_pos": 29, "end_pos": 29, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "VKNVIKEVSGSRGDLIPVDS", "down_seq": "RNSTSFRPYCLLNRKFSSSR", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q9D8T2-1.7.14", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q9D8T2-1.17.20", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9D8T2-1.38.38", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q9D8T2-1.39.39", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.43.54", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.306.310", "start_pos": 306, "end_pos": 310, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.", "journal": "Immunity", "date": "2020", "authors": "Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "LEMEL", "start_aa": "L", "up_seq": "AADFQGLYAEVKACSSELES", "down_seq": "RQQILVNIGKILQDQPSMEA", "mutagenesis": [ { "sequence_org": "LEMEL", "sequence_mut": "AEMEA", "comment": "In 5A mutant; abolished interaction with CASP1; when associated with 361-L--L370.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.292.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q9D8T2-1.295.295", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9D8T2-1.309.313", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.309.313", "start_pos": 309, "end_pos": 313, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion.", "journal": "Nature immunology", "date": "2022-07", "authors": "Chen Wen, Chen Shuangfeng, Yan Chenghua, Zhang Yaguang, Zhang Ronghua, Chen Min, Zhong Shufen, Fan Weiguo, Zhu Songling, Zhang Danyan, Lu Xiao, Zhang Jia, Huang Yuying, Zhu Lin, Li Xuezhen, Lv Dawei, Fu Yadong, Iv Houkun, Ling Zhiyang, Ma Liyan, Jiang Hai, Long Gang, Zhu Jinfang, Wu Dong, Wu Bin, Sun Bing", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "35794369", "url": "https://glygen.org/publication/PubMed/35794369" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "35794369", "url": "https://glygen.org/publication/PubMed/35794369", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "ELRQQ", "start_aa": "E", "up_seq": "FQGLYAEVKACSSELESLEM", "down_seq": "ILVNIGKILQDQPSMEALEA", "mutagenesis": [ { "sequence_org": "ELRQQ", "sequence_mut": "AAAAA", "comment": "Abolished generation of the Gasdermin-D, p40 chain and ability to promote secretion of IL33.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "35794369", "url": "https://glygen.org/publication/PubMed/35794369" } ] }, { "sequence_org": "ELRQQ", "sequence_mut": "", "comment": "Abolished generation of the Gasdermin-D, p40 chain and ability to promote secretion of IL33.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "35794369", "url": "https://glygen.org/publication/PubMed/35794369" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q9D8T2-1.292.292", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.295.295", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9D8T2-1.306.310", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.361.370", "start_pos": 361, "end_pos": 370, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.", "journal": "Immunity", "date": "2020", "authors": "Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "LDSGELVPEL", "start_aa": "L", "up_seq": "SGGQVEPLDGPAGCILECLV", "down_seq": "AAPIFYLLGALAVLSETQQQ", "mutagenesis": [ { "sequence_org": "LDSGELVPEL", "sequence_mut": "ADSGELAPEA", "comment": "In 5A mutant; abolished interaction with CASP1; when associated with 306-L--L310.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q9D8T2-1.369.369", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9D8T2-1.376.376", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q9D8T2-1.380.380", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.369.369", "start_pos": 369, "end_pos": 369, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.", "journal": "Immunity", "date": "2020", "authors": "Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "DGPAGCILECLVLDSGELVP", "down_seq": "LAAPIFYLLGALAVLSETQQ", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "K", "comment": "Impaired interaction and cleavage by CASP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "32553275", "url": "https://glygen.org/publication/PubMed/32553275" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q9D8T2-1.361.370", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9D8T2-1.376.376", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9D8T2-1.380.380", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.376.376", "start_pos": 376, "end_pos": 376, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.", "journal": "Structure (London, England : 1993)", "date": "2018", "authors": "Liu Z, Wang C, Rathkey JK, Yang J, Dubyak GR, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "29576317", "url": "https://glygen.org/publication/PubMed/29576317" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29576317", "url": "https://glygen.org/publication/PubMed/29576317", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LECLVLDSGELVPELAAPIF", "down_seq": "LLGALAVLSETQQQLLAKAL", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "D", "comment": "Spontaneous pyroptosis-inducing activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "29576317", "url": "https://glygen.org/publication/PubMed/29576317" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9D8T2-1.361.370", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q9D8T2-1.369.369", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.380.380", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.380.380", "start_pos": 380, "end_pos": 380, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "VLDSGELVPELAAPIFYLLG", "down_seq": "LAVLSETQQQLLAKALETTV", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "D", "comment": "Disrupts intramolecular interactions and autoinhibition, leading to spontaneous pyroptosis-inducing activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q9D8T2-1.361.370", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q9D8T2-1.369.369", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.376.376", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.39.39", "start_pos": 39, "end_pos": 39, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "SRGDLIPVDSLRNSTSFRPY", "down_seq": "LLNRKFSSSRFWKPRYSCVN", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of oligomerization of Gasdermin-D, N-terminal.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9D8T2-1.17.20", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q9D8T2-1.29.29", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q9D8T2-1.38.38", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.43.54", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q9D8T2-1.50.51", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9D8T2-1.57.57", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.43.54", "start_pos": 43, "end_pos": 54, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "RKFSSSRFWKPR", "start_aa": "R", "up_seq": "LIPVDSLRNSTSFRPYCLLN", "down_seq": "YSCVNLSIKDILEPSAPEPE", "mutagenesis": [ { "sequence_org": "RKFSSSRFWKPR", "sequence_mut": "AAFSSSRFWAPA", "comment": "Reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.29.29", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q9D8T2-1.38.38", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.39.39", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.50.51", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9D8T2-1.57.57", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9D8T2-1.60.60", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.470.470", "start_pos": 470, "end_pos": 470, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRLQVESPQVHWEPTSLIPT", "down_seq": "ALYASLFLLSSLGQKPC", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "R", "comment": "Disrupts intramolecular interactions and autoinhibition, leading to spontaneous pyroptosis-inducing activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.474.474", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.474.474", "start_pos": 474, "end_pos": 474, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "VESPQVHWEPTSLIPTSALY", "down_seq": "SLFLLSSLGQKPC", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "D", "comment": "Disrupts intramolecular interactions and autoinhibition, leading to spontaneous pyroptosis-inducing activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.470.470", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.50.51", "start_pos": 50, "end_pos": 51, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] }, { "title": "Gasdermin D pore structure reveals preferential release of mature interleukin-1.", "journal": "Nature", "date": "2021", "authors": "Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "33883744", "url": "https://glygen.org/publication/PubMed/33883744" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33883744", "url": "https://glygen.org/publication/PubMed/33883744", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "FW", "start_aa": "F", "up_seq": "RNSTSFRPYCLLNRKFSSSR", "down_seq": "KPRYSCVNLSIKDILEPSAP", "mutagenesis": [ { "sequence_org": "FW", "sequence_mut": "GG", "comment": "Abolished ability to form a pore, leading to educed ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" }, { "database": "PubMed", "id": "33883744", "url": "https://glygen.org/publication/PubMed/33883744" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q9D8T2-1.38.38", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q9D8T2-1.39.39", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.43.54", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q9D8T2-1.57.57", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q9D8T2-1.60.60", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.57.57", "start_pos": 57, "end_pos": 57, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "PYCLLNRKFSSSRFWKPRYS", "down_seq": "VNLSIKDILEPSAPEPEPEC", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect on oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q9D8T2-1.38.38", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q9D8T2-1.39.39", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9D8T2-1.43.54", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q9D8T2-1.50.51", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9D8T2-1.60.60", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q9D8T2-1.77.77", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.60.60", "start_pos": 60, "end_pos": 60, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "LLNRKFSSSRFWKPRYSCVN", "down_seq": "SIKDILEPSAPEPEPECFGS", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "G", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9D8T2-1.43.54", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q9D8T2-1.50.51", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9D8T2-1.57.57", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9D8T2-1.77.77", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.77.77", "start_pos": 77, "end_pos": 77, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.", "journal": "Nature", "date": "2016", "authors": "Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "CVNLSIKDILEPSAPEPEPE", "down_seq": "FGSFKVSDVVDGNIQGRVML", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "No effect on oligomerization.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "27383986", "url": "https://glygen.org/publication/PubMed/27383986" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q9D8T2-1.57.57", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q9D8T2-1.60.60", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.81.81", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9D8T2-1.85.88", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q9D8T2-1.95.95", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.7.14", "start_pos": 7, "end_pos": 14, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "KVVKNVIK", "start_aa": "K", "up_seq": "MPSAFE", "down_seq": "EVSGSRGDLIPVDSLRNSTS", "mutagenesis": [ { "sequence_org": "KVVKNVIK", "sequence_mut": "AVVANVIA", "comment": "Reduced ability to induct pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q9D8T2-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9D8T2-1.17.20", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q9D8T2-1.29.29", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.81.81", "start_pos": 81, "end_pos": 81, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "SIKDILEPSAPEPEPECFGS", "down_seq": "KVSDVVDGNIQGRVMLSGMG", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "D", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.77.77", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.85.88", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q9D8T2-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.95.95", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.85.88", "start_pos": 85, "end_pos": 88, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.", "journal": "Cell", "date": "2023-07-06", "authors": "He Kaixin, Wan Tingting, Wang Decai, Hu Ji, Zhou Tingyue, Tao Wanyin, Wei Zheng, Lu Qiao, Zhou Rongbin, Tian Zhigang, Flavell Richard A, Zhu Shu", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "37327784", "url": "https://glygen.org/publication/PubMed/37327784" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "37327784", "url": "https://glygen.org/publication/PubMed/37327784", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "DVVD", "start_aa": "D", "up_seq": "ILEPSAPEPEPECFGSFKVS", "down_seq": "GNIQGRVMLSGMGEGKISGG", "mutagenesis": [ { "sequence_org": "DVVD", "sequence_mut": "AAAA", "comment": "Abolished cleavage by CASP3 and CASP7.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "37327784", "url": "https://glygen.org/publication/PubMed/37327784" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q9D8T2-1.77.77", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.81.81", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q9D8T2-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q9D8T2-1.95.95", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q9D8T2-1.105.105", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.91.91", "start_pos": 91, "end_pos": 91, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "PEPEPECFGSFKVSDVVDGN", "down_seq": "QGRVMLSGMGEGKISGGAAV", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "D", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.77.77", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q9D8T2-1.81.81", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q9D8T2-1.85.88", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q9D8T2-1.95.95", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q9D8T2-1.105.105", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.", "journal": "Immunity", "date": "2019", "authors": "Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "reference": [ { "type": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "PECFGSFKVSDVVDGNIQGR", "down_seq": "MLSGMGEGKISGGAAVSDSS", "mutagenesis": [ { "sequence_org": "V", "sequence_mut": "D", "comment": "Reduced homoolimerization, leading to reduced ability to induce pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" }, { "database": "PubMed", "id": "31097341", "url": "https://glygen.org/publication/PubMed/31097341" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q9D8T2-1.77.77", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q9D8T2-1.81.81", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q9D8T2-1.85.88", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q9D8T2-1.91.91", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q9D8T2-1.105.105", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9D8T2-1.38.38", "start_pos": 38, "end_pos": 38, "uniprot_canonical_ac": "Q9D8T2-1", "length": 487, "uniprot_id": "GSDMD_MOUSE", "protein_name": "Gasdermin-D", "refseq_ac": "NP_081236", "refseq_name": "gasdermin-D", "gene_name": "Gsdmd", "gene_names_uniprotkb": "Gsdmd; Gsdmdc1", "gene_names_refseq": "1810036L03Rik; DF5L; Dfna5l; GsdmD-1; Gsdmdc1; Gsdmd; M2-4", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "GSRGDLIPVDSLRNSTSFRP", "down_seq": "CLLNRKFSSSRFWKPRYSCV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q9D8T2", "url": "https://www.uniprot.org/uniprotkb/Q9D8T2" } ], "site_lbl": "Tyr38" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "105", "end_pos": "105" }, { "start_pos": "122", "end_pos": "122" }, { "start_pos": "138", "end_pos": "138" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "152", "end_pos": "152" }, { "start_pos": "154", "end_pos": "154" }, { "start_pos": "17", "end_pos": "20" }, { "start_pos": "192", "end_pos": "192" }, { "start_pos": "193", "end_pos": "193" }, { "start_pos": "230", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "249", "end_pos": "249" }, { "start_pos": "265", "end_pos": "265" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "276", "end_pos": "276" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "306", "end_pos": "310" }, { "start_pos": "309", "end_pos": "313" }, { "start_pos": "361", "end_pos": "370" }, { "start_pos": "369", "end_pos": "369" }, { "start_pos": "376", "end_pos": "376" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "39", "end_pos": "39" }, { "start_pos": "43", "end_pos": "54" }, { "start_pos": "470", "end_pos": "470" }, { "start_pos": "474", "end_pos": "474" }, { "start_pos": "50", "end_pos": "51" }, { "start_pos": "57", "end_pos": "57" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "77", "end_pos": "77" }, { "start_pos": "7", "end_pos": "14" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "85", "end_pos": "88" }, { "start_pos": "91", "end_pos": "91" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q9D8T2-1.17.20", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q9D8T2-1.29.29", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q9D8T2-1.39.39", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q9D8T2-1.43.54", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q9D8T2-1.50.51", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q9D8T2-1.57.57", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9WV60-1.389.389", "start_pos": 389, "end_pos": 389, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-kappaB activities in mice.", "journal": "Hypertension research : official journal of the Japanese Society of Hypertension", "date": "2019", "authors": "Nakagawa T, Furukawa Y, Hayashi T, Nomura A, Yokoe S, Moriwaki K, Kato R, Ijiri Y, Yamaguchi T, Izumi Y, Yoshiyama M, Asahi M", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31409917", "url": "https://glygen.org/publication/PubMed/31409917" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "O'Donnell N, Zachara NE, Hart GW, Marth JD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "14749383", "url": "https://glygen.org/publication/PubMed/14749383" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2002", "authors": "Vosseller K, Wells L, Lane MD, Hart GW", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "11959983", "url": "https://glygen.org/publication/PubMed/11959983" } ] }, { "title": "O-GlcNAcylation-induced GSK-3\u03b2 activation deteriorates pressure overload-induced heart failure via lack of compensatory cardiac hypertrophy in mice.", "journal": "Frontiers in endocrinology", "date": "2023", "authors": "Matsuno Mahito, Yokoe Shunichi, Nagatsuka Takehiro, Morihara Hirofumi, Moriwaki Kazumasa, Asahi Michio", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "37033243", "url": "https://glygen.org/publication/PubMed/37033243" } ] }, { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] }, { "title": "Failure to Inactivate Nuclear GSK3beta by Ser(389)-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response.", "journal": "Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology", "date": "2018", "authors": "Thornton TM, Hare B, Colie S, Pendlebury WW, Nebreda AR, Falls W, Jaworski DM, Rincon M", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28832021", "url": "https://glygen.org/publication/PubMed/28832021" } ] } ], "crossref": [ { "id": "31409917", "url": "https://glygen.org/publication/PubMed/31409917", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14749383", "url": "https://glygen.org/publication/PubMed/14749383", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11959983", "url": "https://glygen.org/publication/PubMed/11959983", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37033243", "url": "https://glygen.org/publication/PubMed/37033243", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "28832021", "url": "https://glygen.org/publication/PubMed/28832021", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SNPPLATILIPPHARIQAAA", "down_seq": "PPANATAASDTNAGDRGQTN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser389", "evidence": [ { "id": "31409917", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/31409917" }, { "id": "Q9WV60", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "14749383", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/14749383" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "11959983", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11959983" }, { "id": "37033243", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37033243" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "28832021", "url": "https://glygen.org/publication/PubMed/28832021" } ], "site_lbl": "Ser389" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q9WV60-1.395.395", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.395.395", "start_pos": 395, "end_pos": 395, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-kappaB activities in mice.", "journal": "Hypertension research : official journal of the Japanese Society of Hypertension", "date": "2019", "authors": "Nakagawa T, Furukawa Y, Hayashi T, Nomura A, Yokoe S, Moriwaki K, Kato R, Ijiri Y, Yamaguchi T, Izumi Y, Yoshiyama M, Asahi M", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31409917", "url": "https://glygen.org/publication/PubMed/31409917" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "O'Donnell N, Zachara NE, Hart GW, Marth JD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "14749383", "url": "https://glygen.org/publication/PubMed/14749383" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2002", "authors": "Vosseller K, Wells L, Lane MD, Hart GW", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "11959983", "url": "https://glygen.org/publication/PubMed/11959983" } ] }, { "title": "O-GlcNAcylation-induced GSK-3\u03b2 activation deteriorates pressure overload-induced heart failure via lack of compensatory cardiac hypertrophy in mice.", "journal": "Frontiers in endocrinology", "date": "2023", "authors": "Matsuno Mahito, Yokoe Shunichi, Nagatsuka Takehiro, Morihara Hirofumi, Moriwaki Kazumasa, Asahi Michio", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "37033243", "url": "https://glygen.org/publication/PubMed/37033243" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q9WV60", "url": "https://oglcnac.org/atlas/detail/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "31409917", "url": "https://glygen.org/publication/PubMed/31409917", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14749383", "url": "https://glygen.org/publication/PubMed/14749383", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11959983", "url": "https://glygen.org/publication/PubMed/11959983", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37033243", "url": "https://glygen.org/publication/PubMed/37033243", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://oglcnac.org/atlas/detail/Q9WV60", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TILIPPHARIQAAASPPANA", "down_seq": "AASDTNAGDRGQTNNAASAS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr395", "evidence": [ { "id": "31409917", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/31409917" }, { "id": "Q9WV60", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "14749383", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/14749383" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "11959983", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11959983" }, { "id": "37033243", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37033243" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q9WV60", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q9WV60" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q9WV60-1.389.389", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.417.417", "start_pos": 417, "end_pos": 417, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q9WV60", "url": "https://oglcnac.org/atlas/detail/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://oglcnac.org/atlas/detail/Q9WV60", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASDTNAGDRGQTNNAASASA", "down_seq": "NST", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser417", "evidence": [ { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "Q9WV60", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q9WV60" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.9.9", "start_pos": 9, "end_pos": 9, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-kappaB activities in mice.", "journal": "Hypertension research : official journal of the Japanese Society of Hypertension", "date": "2019", "authors": "Nakagawa T, Furukawa Y, Hayashi T, Nomura A, Yokoe S, Moriwaki K, Kato R, Ijiri Y, Yamaguchi T, Izumi Y, Yoshiyama M, Asahi M", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31409917", "url": "https://glygen.org/publication/PubMed/31409917" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "O'Donnell N, Zachara NE, Hart GW, Marth JD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "14749383", "url": "https://glygen.org/publication/PubMed/14749383" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2002", "authors": "Vosseller K, Wells L, Lane MD, Hart GW", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "11959983", "url": "https://glygen.org/publication/PubMed/11959983" } ] }, { "title": "O-GlcNAcylation-induced GSK-3\u03b2 activation deteriorates pressure overload-induced heart failure via lack of compensatory cardiac hypertrophy in mice.", "journal": "Frontiers in endocrinology", "date": "2023", "authors": "Matsuno Mahito, Yokoe Shunichi, Nagatsuka Takehiro, Morihara Hirofumi, Moriwaki Kazumasa, Asahi Michio", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "37033243", "url": "https://glygen.org/publication/PubMed/37033243" } ] }, { "title": "Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.", "journal": "The EMBO journal", "date": "2005", "authors": "McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R, Alessi DR", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15791206", "url": "https://glygen.org/publication/PubMed/15791206" } ] }, { "title": "ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation.", "journal": "Nature cell biology", "date": "2011", "authors": "Wakatsuki S, Saitoh F, Araki T", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22057101", "url": "https://glygen.org/publication/PubMed/22057101" } ] }, { "title": "Inhibition of ERK1/2 Restores GSK3\u03b2 Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis.", "journal": "Scientific reports", "date": "2017-06-23", "authors": "Pal Rituraj, Bondar Vitaliy V, Adamski Carolyn J, Rodney George G, Sardiello Marco", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28646232", "url": "https://glygen.org/publication/PubMed/28646232" } ] }, { "title": "Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Valerio A, Ghisi V, Dossena M, Tonello C, Giordano A, Frontini A, Ferrario M, Pizzi M, Spano P, Carruba MO, Nisoli E", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16522636", "url": "https://glygen.org/publication/PubMed/16522636" } ] }, { "title": "The A-kinase Anchoring Protein GSKIP Regulates GSK3beta Activity and Controls Palatal Shelf Fusion in Mice.", "journal": "The Journal of biological chemistry", "date": "2016", "authors": "Deak VA, Skroblin P, Dittmayer C, Knobeloch KP, Bachmann S, Klussmann E", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26582204", "url": "https://glygen.org/publication/PubMed/26582204" } ] }, { "title": "Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Hashimoto M, Sagara Y, Langford D, Everall IP, Mallory M, Everson A, Digicaylioglu M, Masliah E", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "12095987", "url": "https://glygen.org/publication/PubMed/12095987" } ] }, { "title": "Expression, localization, and activity of glycogen synthase kinase 3beta during mouse skin tumorigenesis.", "journal": "Molecular carcinogenesis", "date": "2002", "authors": "Leis H, Segrelles C, Ruiz S, Santos M, Paramio JM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "12489109", "url": "https://glygen.org/publication/PubMed/12489109" } ] }, { "title": "Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium.", "journal": "Neuropharmacology", "date": "2002", "authors": "De Sarno P, Li X, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "12504922", "url": "https://glygen.org/publication/PubMed/12504922" } ] }, { "title": "Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia.", "journal": "Nature genetics", "date": "2004", "authors": "Emamian ES, Hall D, Birnbaum MJ, Karayiorgou M, Gogos JA", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "14745448", "url": "https://glygen.org/publication/PubMed/14745448" } ] }, { "title": "In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain.", "journal": "Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology", "date": "2004", "authors": "Li X, Zhu W, Roh MS, Friedman AB, Rosborough K, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15039769", "url": "https://glygen.org/publication/PubMed/15039769" } ] }, { "title": "Anesthesia and post-mortem interval profoundly influence the regulatory serine phosphorylation of glycogen synthase kinase-3 in mouse brain.", "journal": "Journal of neurochemistry", "date": "2005", "authors": "Li X, Friedman AB, Roh MS, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15659239", "url": "https://glygen.org/publication/PubMed/15659239" } ] }, { "title": "Mechanisms of cytoplasmic {beta}-catenin accumulation and its involvement in tumorigenic activities mediated by oncogenic splicing variant of the receptor originated from Nantes tyrosine kinase.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Xu XM, Zhou YQ, Wang MH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15878878", "url": "https://glygen.org/publication/PubMed/15878878" } ] }, { "title": "Wnt/beta-catenin signaling activates growth-control genes during overload-induced skeletal muscle hypertrophy.", "journal": "American journal of physiology. Cell physiology", "date": "2005", "authors": "Armstrong DD, Esser KA", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15888552", "url": "https://glygen.org/publication/PubMed/15888552" } ] }, { "title": "Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Harada Y, Sakai M, Kurabayashi N, Hirota T, Fukada Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15980066", "url": "https://glygen.org/publication/PubMed/15980066" } ] }, { "title": "The effect of insulin deficiency on tau and neurofilament in the insulin knockout mouse.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Schechter R, Beju D, Miller KE", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16039605", "url": "https://glygen.org/publication/PubMed/16039605" } ] }, { "title": "Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth.", "journal": "The Journal of clinical investigation", "date": "2006", "authors": "Dong X, Park S, Lin X, Copps K, Yi X, White MF", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16374520", "url": "https://glygen.org/publication/PubMed/16374520" } ] }, { "title": "Implication of the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in the neuroprotective effect of estradiol in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.", "journal": "Molecular pharmacology", "date": "2006", "authors": "D'Astous M, Mendez P, Morissette M, Garcia-Segura LM, Di Paolo T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16434614", "url": "https://glygen.org/publication/PubMed/16434614" } ] }, { "title": "Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3beta in irradiated vascular endothelium.", "journal": "Cancer research", "date": "2006", "authors": "Tan J, Geng L, Yazlovitskaya EM, Hallahan DE", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16489037", "url": "https://glygen.org/publication/PubMed/16489037" } ] }, { "title": "Hepatocyte growth factor suppresses acute renal inflammation by inhibition of endothelial E-selectin.", "journal": "Kidney international", "date": "2006-04", "authors": "Gong R, Rifai A, Dworkin L D", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16501492", "url": "https://glygen.org/publication/PubMed/16501492" } ] }, { "title": "Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.", "journal": "Genes & development", "date": "2006", "authors": "Wu X, Quondamatteo F, Lefever T, Czuchra A, Meyer H, Chrostek A, Paus R, Langbein L, Brakebusch C", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16510873", "url": "https://glygen.org/publication/PubMed/16510873" } ] }, { "title": "Glycogen synthase kinase 3beta together with 14-3-3 protein regulates diabetic cardiomyopathy: effect of losartan and tempol.", "journal": "FEBS letters", "date": "2006", "authors": "Gurusamy N, Watanabe K, Ma M, Prakash P, Hirabayashi K, Zhang S, Muslin AJ, Kodama M, Aizawa Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16530186", "url": "https://glygen.org/publication/PubMed/16530186" } ] }, { "title": "The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology.", "journal": "The American journal of pathology", "date": "2006", "authors": "Okada T, Ishii Y, Masujin K, Yasoshima A, Matsuda J, Ogura A, Nakayama H, Kunieda T, Doi K", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16565488", "url": "https://glygen.org/publication/PubMed/16565488" } ] }, { "title": "Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture.", "journal": "Journal of neurochemistry", "date": "2006", "authors": "Wang ZF, Li HL, Li XC, Zhang Q, Tian Q, Wang Q, Xu H, Wang JZ", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16762022", "url": "https://glygen.org/publication/PubMed/16762022" } ] }, { "title": "Glycogen synthase kinase-3 regulation of chromatin segregation and cytokinesis in mouse preimplantation embryos.", "journal": "Molecular reproduction and development", "date": "2007", "authors": "Acevedo N, Wang X, Dunn RL, Smith GD", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16941690", "url": "https://glygen.org/publication/PubMed/16941690" } ] }, { "title": "Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3beta) independently of Akt/PKB serine phosphorylation.", "journal": "Journal of cell science", "date": "2006", "authors": "Gartner A, Huang X, Hall A", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16954147", "url": "https://glygen.org/publication/PubMed/16954147" } ] }, { "title": "Endogenously activated mGlu5 metabotropic glutamate receptors sustain the increase in c-Myc expression induced by leukaemia inhibitory factor in cultured mouse embryonic stem cells.", "journal": "Journal of neurochemistry", "date": "2006", "authors": "Spinsanti P, De Vita T, Di Castro S, Storto M, Formisano P, Nicoletti F, Melchiorri D", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16987252", "url": "https://glygen.org/publication/PubMed/16987252" } ] }, { "title": "Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.", "journal": "American journal of physiology. Gastrointestinal and liver physiology", "date": "2007", "authors": "Umar S, Wang Y, Morris AP, Sellin JH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "17053159", "url": "https://glygen.org/publication/PubMed/17053159" } ] }, { "title": "Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.", "journal": "The European journal of neuroscience", "date": "2007", "authors": "Hooper C, Markevich V, Plattner F, Killick R, Schofield E, Engel T, Hernandez F, Anderton B, Rosenblum K, Bliss T, Cooke SF, Avila J, Lucas JJ, Giese KP, Stephenson J, Lovestone S", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "17241269", "url": "https://glygen.org/publication/PubMed/17241269" } ] }, { "title": "Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Sengupta S, Jayaraman P, Chilton PM, Casella CR, Mitchell TC", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "17475833", "url": "https://glygen.org/publication/PubMed/17475833" } ] }, { "title": "GSK-3beta mediates in the progesterone inhibition of estrogen induced cyclin D2 nuclear localization and cell proliferation in cyclin D1-/- mouse uterine epithelium.", "journal": "FEBS letters", "date": "2007", "authors": "Wang Y, Feng H, Bi C, Zhu L, Pollard JW, Chen B", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "17560576", "url": "https://glygen.org/publication/PubMed/17560576" } ] }, { "title": "bFGF promotes photoreceptor cell survival in vitro by PKA-mediated inactivation of glycogen synthase kinase 3beta and CREB-dependent Bcl-2 up-regulation.", "journal": "Journal of neurochemistry", "date": "2007-11", "authors": "O'Driscoll Carolyn, Wallace Deborah, Cotter Thomas G", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "17714451", "url": "https://glygen.org/publication/PubMed/17714451" } ] }, { "title": "Effects of wortmannin on phosphorylation of PDK1, GSK3-beta, PTEN and expression of Skp2 mRNA after ischemia/reperfusion injury in the mouse kidney.", "journal": "International urology and nephrology", "date": "2008", "authors": "Zheng X, Xie L, Qin J, Shen H, Chen Z, Jin Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "17975737", "url": "https://glygen.org/publication/PubMed/17975737" } ] }, { "title": "Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2008", "authors": "Wen Y, Planel E, Herman M, Figueroa HY, Wang L, Liu L, Lau LF, Yu WH, Duff KE", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "18322105", "url": "https://glygen.org/publication/PubMed/18322105" } ] }, { "title": "Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Mariappan MM, Shetty M, Sataranatarajan K, Choudhury GG, Kasinath BS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "18701453", "url": "https://glygen.org/publication/PubMed/18701453" } ] }, { "title": "AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "18801732", "url": "https://glygen.org/publication/PubMed/18801732" } ] }, { "title": "Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3beta-dependent mechanisms.", "journal": "Molecular and cellular biology", "date": "2008", "authors": "Liu R, Wang L, Chen C, Liu Y, Zhou P, Wang Y, Wang X, Turnbull J, Minassian BA, Liu Y, Zheng P", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "18824542", "url": "https://glygen.org/publication/PubMed/18824542" } ] }, { "title": "Airway smooth muscle hyperplasia and hypertrophy correlate with glycogen synthase kinase-3(beta) phosphorylation in a mouse model of asthma.", "journal": "American journal of physiology. Lung cellular and molecular physiology", "date": "2009", "authors": "Bentley JK, Deng H, Linn MJ, Lei J, Dokshin GA, Fingar DC, Bitar KN, Henderson WR Jr, Hershenson MB", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19011050", "url": "https://glygen.org/publication/PubMed/19011050" } ] }, { "title": "Neuroprotective effects of (+/-)-catechin against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mice.", "journal": "Neuroscience letters", "date": "2009", "authors": "Ruan H, Yang Y, Zhu X, Wang X, Chen R", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19070648", "url": "https://glygen.org/publication/PubMed/19070648" } ] }, { "title": "Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Matsuda T, Zhai P, Maejima Y, Hong C, Gao S, Tian B, Goto K, Takagi H, Tamamori-Adachi M, Kitajima S, Sadoshima J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19106302", "url": "https://glygen.org/publication/PubMed/19106302" } ] }, { "title": "Cadmium toxicity toward autophagy through ROS-activated GSK-3beta in mesangial cells.", "journal": "Toxicological sciences : an official journal of the Society of Toxicology", "date": "2009", "authors": "Wang SH, Shih YL, Kuo TC, Ko WC, Shih CM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19126599", "url": "https://glygen.org/publication/PubMed/19126599" } ] }, { "title": "Cocaine-induced hyperactivity and sensitization are dependent on GSK3.", "journal": "Neuropharmacology", "date": "2009", "authors": "Miller JS, Tallarida RJ, Unterwald EM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19328817", "url": "https://glygen.org/publication/PubMed/19328817" } ] }, { "title": "PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.", "journal": "Molecular immunology", "date": "2009", "authors": "Gruber T, Hermann-Kleiter N, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Thuille N, Letschka T, Barsig J, Baudler M, Li J, Metzler B, Nusslein-Hildesheim B, Wagner J, Leitges M, Baier G", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19356803", "url": "https://glygen.org/publication/PubMed/19356803" } ] }, { "title": "GSK3beta, a centre-staged kinase in neuropsychiatric disorders, modulates long term memory by inhibitory phosphorylation at serine-9.", "journal": "Neurobiology of disease", "date": "2009", "authors": "Dewachter I, Ris L, Jaworski T, Seymour CM, Kremer A, Borghgraef P, De Vijver H, Godaux E, Van Leuven F", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19379814", "url": "https://glygen.org/publication/PubMed/19379814" } ] }, { "title": "BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance.", "journal": "Journal of cellular and molecular medicine", "date": "2010", "authors": "Dobashi T, Tanabe S, Jin H, Mimura N, Yamamoto T, Nishino T, Aoe T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19818092", "url": "https://glygen.org/publication/PubMed/19818092" } ] }, { "title": "Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.", "journal": "Current Alzheimer research", "date": "2010", "authors": "Zhuo JM, Portugal GS, Kruger WD, Wang H, Gould TJ, Pratico D", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19939226", "url": "https://glygen.org/publication/PubMed/19939226" } ] }, { "title": "Light and electron microscopy study of glycogen synthase kinase-3beta in the mouse brain.", "journal": "PloS one", "date": "2010", "authors": "Perez-Costas E, Gandy JC, Melendez-Ferro M, Roberts RC, Bijur GN", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "20111716", "url": "https://glygen.org/publication/PubMed/20111716" } ] }, { "title": "Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.", "journal": "Diabetes", "date": "2010", "authors": "Kumar A, Lawrence JC Jr, Jung DY, Ko HJ, Keller SR, Kim JK, Magnuson MA, Harris TE", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "20332342", "url": "https://glygen.org/publication/PubMed/20332342" } ] }, { "title": "Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2010", "authors": "Kapfhamer D, Berger KH, Hopf FW, Seif T, Kharazia V, Bonci A, Heberlein U", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "20592205", "url": "https://glygen.org/publication/PubMed/20592205" } ] }, { "title": "CRH and SRIF have opposite effects on the Wnt/beta-catenin signalling pathway through PKA/GSK-3beta in corticotroph pituitary cells.", "journal": "Cancer investigation", "date": "2010", "authors": "Khattak MN, Buchfelder M, Kleindienst A, Schofl C, Kremenevskaja N", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "20690801", "url": "https://glygen.org/publication/PubMed/20690801" } ] }, { "title": "Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8.", "journal": "PloS one", "date": "2010", "authors": "Aguilar-Morante D, Morales-Garcia JA, Sanz-SanCristobal M, Garcia-Cabezas MA, Santos A, Perez-Castillo A", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21079728", "url": "https://glygen.org/publication/PubMed/21079728" } ] }, { "title": "Progranulin enhances neural progenitor cell proliferation through glycogen synthase kinase 3beta phosphorylation.", "journal": "Neuroscience", "date": "2011", "authors": "Nedachi T, Kawai T, Matsuwaki T, Yamanouchi K, Nishihara M", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21540081", "url": "https://glygen.org/publication/PubMed/21540081" } ] }, { "title": "Interplay between glycogen synthase kinase-3beta and tau in the cerebellum of Hsp27 transgenic mouse.", "journal": "Journal of neuroscience research", "date": "2011", "authors": "Wang S, Toth ME, Bereczki E, Santha M, Guan ZZ, Winblad B, Pei JJ", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21544852", "url": "https://glygen.org/publication/PubMed/21544852" } ] }, { "title": "Cdc42 controls vascular network assembly through protein kinase Ciota during embryonic vasculogenesis.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2011", "authors": "Qi Y, Liu J, Wu X, Brakebusch C, Leitges M, Han Y, Corbett SA, Lowry SF, Graham AM, Li S", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21659643", "url": "https://glygen.org/publication/PubMed/21659643" } ] }, { "title": "Cyanidin-3-glucoside ameliorates ethanol neurotoxicity in the developing brain.", "journal": "Journal of neuroscience research", "date": "2011", "authors": "Ke Z, Liu Y, Wang X, Fan Z, Chen G, Xu M, Bower KA, Frank JA, Ou X, Shi X, Luo J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21671257", "url": "https://glygen.org/publication/PubMed/21671257" } ] }, { "title": "An important role for Akt3 in platelet activation and thrombosis.", "journal": "Blood", "date": "2011", "authors": "O'Brien KA, Stojanovic-Terpo A, Hay N, Du X", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21821713", "url": "https://glygen.org/publication/PubMed/21821713" } ] }, { "title": "Endoplasmic reticulum stress and glycogen synthase kinase-3beta activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2012", "authors": "McAlpine CS, Bowes AJ, Khan MI, Shi Y, Werstuck GH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21998135", "url": "https://glygen.org/publication/PubMed/21998135" } ] }, { "title": "GSK-3beta activation mediates Nogo-66-induced inhibition of neurite outgrowth in N2a cells.", "journal": "Neuroscience letters", "date": "2011", "authors": "Shen JY, Yi XX, Xiong NX, Wang HJ, Duan XW, Zhao HY", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22019984", "url": "https://glygen.org/publication/PubMed/22019984" } ] }, { "title": "HDAC6 regulates LPS-tolerance in astrocytes.", "journal": "PloS one", "date": "2011", "authors": "Beurel E", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22022450", "url": "https://glygen.org/publication/PubMed/22022450" } ] }, { "title": "Frat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3beta subcellular localization in pluripotent cells.", "journal": "Molecular and cellular biology", "date": "2012", "authors": "Bechard M, Trost R, Singh AM, Dalton S", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22064483", "url": "https://glygen.org/publication/PubMed/22064483" } ] }, { "title": "B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation.", "journal": "PloS one", "date": "2012", "authors": "Wang X, Hao J, Metzger DL, Ao Z, Chen L, Ou D, Verchere CB, Mui A, Warnock GL", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22238573", "url": "https://glygen.org/publication/PubMed/22238573" } ] }, { "title": "Brain region differences in regulation of Akt and GSK3 by chronic stimulant administration in mice.", "journal": "Cellular signalling", "date": "2012", "authors": "Mines MA, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22434044", "url": "https://glygen.org/publication/PubMed/22434044" } ] }, { "title": "Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells.", "journal": "BMC complementary and alternative medicine", "date": "2012", "authors": "Kim GS, Park HJ, Woo JH, Kim MK, Koh PO, Min W, Ko YG, Kim CH, Won CK, Cho JH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22471389", "url": "https://glygen.org/publication/PubMed/22471389" } ] }, { "title": "Inhibition of GSK-3beta ameliorates hepatic ischemia-reperfusion injury through GSK-3beta/beta-catenin signaling pathway in mice.", "journal": "Hepatobiliary & pancreatic diseases international : HBPD INT", "date": "2012", "authors": "Xia YX, Lu L, Wu ZS, Pu LY, Sun BC, Wang XH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22672822", "url": "https://glygen.org/publication/PubMed/22672822" } ] }, { "title": "Flurbiprofen, a cyclooxygenase inhibitor, protects mice from hepatic ischemia/reperfusion injury by inhibiting GSK-3beta signaling and mitochondrial permeability transition.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2012", "authors": "Fu H, Chen H, Wang C, Xu H, Liu F, Guo M, Wang Q, Shi X", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22714712", "url": "https://glygen.org/publication/PubMed/22714712" } ] }, { "title": "Lithium exacerbates hepatic ischemia/reperfusion injury by inhibiting GSK-3beta/NF-kappaB-mediated protective signaling in mice.", "journal": "European journal of pharmacology", "date": "2012", "authors": "Xia Y, Rao J, Yao A, Zhang F, Li G, Wang X, Lu L", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23051669", "url": "https://glygen.org/publication/PubMed/23051669" } ] }, { "title": "Dual regulation of glycogen synthase kinase 3 (GSK3)alpha/beta by protein kinase C (PKC)alpha and Akt promotes thrombin-mediated integrin alphaIIbbeta3 activation and granule secretion in platelets.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Moore SF, van den Bosch MT, Hunter RW, Sakamoto K, Poole AW, Hers I", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23239877", "url": "https://glygen.org/publication/PubMed/23239877" } ] }, { "title": "Acute inhibition of central c-Jun N-terminal kinase restores hypothalamic insulin signalling and alleviates glucose intolerance in diabetic mice.", "journal": "Journal of neuroendocrinology", "date": "2013", "authors": "Benzler J, Ganjam GK, Legler K, Stohr S, Kruger M, Steger J, Tups A", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23301857", "url": "https://glygen.org/publication/PubMed/23301857" } ] }, { "title": "Inhibitory phosphorylation of GSK-3beta by AKT, PKA, and PI3K contributes to high NaCl-induced activation of the transcription factor NFAT5 (TonEBP/OREBP).", "journal": "American journal of physiology. Renal physiology", "date": "2013", "authors": "Zhou X, Wang H, Burg MB, Ferraris JD", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23324178", "url": "https://glygen.org/publication/PubMed/23324178" } ] }, { "title": "6-gingerol prevents adipogenesis and the accumulation of cytoplasmic lipid droplets in 3T3-L1 cells.", "journal": "Phytomedicine : international journal of phytotherapy and phytopharmacology", "date": "2013", "authors": "Tzeng TF, Liu IM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23369342", "url": "https://glygen.org/publication/PubMed/23369342" } ] }, { "title": "PDK1 regulates platelet activation and arterial thrombosis.", "journal": "Blood", "date": "2013", "authors": "Chen X, Zhang Y, Wang Y, Li D, Zhang L, Wang K, Luo X, Yang Z, Wu Y, Liu J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23444402", "url": "https://glygen.org/publication/PubMed/23444402" } ] }, { "title": "Over-expression of calpastatin aggravates cardiotoxicity induced by doxorubicin.", "journal": "Cardiovascular research", "date": "2013", "authors": "Wang Y, Zheng D, Wei M, Ma J, Yu Y, Chen R, Lacefield JC, Xu H, Peng T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23455548", "url": "https://glygen.org/publication/PubMed/23455548" } ] }, { "title": "Effects of acute and chronic electroconvulsive shocks on glycogen synthase kinase 3beta level and phosphorylation in mice.", "journal": "The journal of ECT", "date": "2013", "authors": "Basar K, Eren-Kocak E, Ozdemir H, Ertugrul A", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23807397", "url": "https://glygen.org/publication/PubMed/23807397" } ] }, { "title": "Antidepressant-like effect of alpha-tocopherol in a mouse model of depressive-like behavior induced by TNF-alpha.", "journal": "Progress in neuro-psychopharmacology & biological psychiatry", "date": "2013", "authors": "Manosso LM, Neis VB, Moretti M, Daufenbach JF, Freitas AE, Colla AR, Rodrigues AL", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23816813", "url": "https://glygen.org/publication/PubMed/23816813" } ] }, { "title": "Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3beta in pancreatic beta-cells.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Semache M, Zarrouki B, Fontes G, Fogarty S, Kikani C, Chawki MB, Rutter J, Poitout V", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23853095", "url": "https://glygen.org/publication/PubMed/23853095" } ] }, { "title": "[APPL1-mediated effects of leptin on activity of GSK-3beta in C2C12 cell].", "journal": "Zhonghua yi xue za zhi", "date": "2013", "authors": "Xu M, Xiao YY, Han JF, Yin J, Lu JX, Liu RB, Wei L, Bao YQ, Jia WP", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24025512", "url": "https://glygen.org/publication/PubMed/24025512" } ] }, { "title": "CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2013", "authors": "Marques JM, Rodrigues RJ, Valbuena S, Rozas JL, Selak S, Marin P, Aller MI, Lerma J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24227739", "url": "https://glygen.org/publication/PubMed/24227739" } ] }, { "title": "Differential effects of beta-catenin and NF-kappaB interplay in the regulation of cell proliferation, inflammation and tumorigenesis in response to bacterial infection.", "journal": "PloS one", "date": "2013", "authors": "Chandrakesan P, Jakkula LU, Ahmed I, Roy B, Anant S, Umar S", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24278135", "url": "https://glygen.org/publication/PubMed/24278135" } ] }, { "title": "Effect of adiponectin on cardiac beta-catenin signaling pathway under angiotensin II infusion.", "journal": "Biochemical and biophysical research communications", "date": "2014", "authors": "Fujishima Y, Maeda N, Matsuda K, Komura N, Hirata A, Mori T, Sekimoto R, Tsushima Y, Nishizawa H, Funahashi T, Shimomura I", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24462873", "url": "https://glygen.org/publication/PubMed/24462873" } ] }, { "title": "DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3beta and expressions of cyclin D1 and TCF7L2 in cancer model mice.", "journal": "Biochemical pharmacology", "date": "2014", "authors": "Takahashi-Yanaga F, Yoshihara T, Jingushi K, Igawa K, Tomooka K, Watanabe Y, Morimoto S, Nakatsu Y, Tsuzuki T, Nakabeppu Y, Sasaguri T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24670930", "url": "https://glygen.org/publication/PubMed/24670930" } ] }, { "title": "Effects of resveratrol on the insulin signaling pathway of obese mice.", "journal": "Journal of veterinary science", "date": "2014", "authors": "Hong HJ, Kang W, Kim DG, Lee DH, Lee Y, Han CH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24675832", "url": "https://glygen.org/publication/PubMed/24675832" } ] }, { "title": "Linoleic acid derivative DCP-LA ameliorates stress-induced depression-related behavior by promoting cell surface 5-HT1A receptor translocation, stimulating serotonin release, and inactivating GSK-3beta.", "journal": "Molecular neurobiology", "date": "2015", "authors": "Kanno T, Tanaka A, Nishizaki T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24788685", "url": "https://glygen.org/publication/PubMed/24788685" } ] }, { "title": "Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin \u03b1IIb\u03b23.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2014-09", "authors": "Jones Chris I, Sage Tanya, Moraes Leonardo A, Vaiyapuri Sakthivel, Hussain Umara, Tucker Katherine L, Barrett Natasha E, Gibbins Jonathan M", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24969778", "url": "https://glygen.org/publication/PubMed/24969778" } ] }, { "title": "Glycogen synthase kinase-3 regulates production of amyloid-beta peptides and tau phosphorylation in diabetic rat brain.", "journal": "TheScientificWorldJournal", "date": "2014", "authors": "Qu ZS, Li L, Sun XJ, Zhao YW, Zhang J, Geng Z, Fu JL, Ren QG", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24983010", "url": "https://glygen.org/publication/PubMed/24983010" } ] }, { "title": "Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3beta Signaling in Human Tau Transgenic Mice.", "journal": "Frontiers in aging neuroscience", "date": "2014", "authors": "Zhang Y, Ma RH, Li XC, Zhang JY, Shi HR, Wei W, Luo DJ, Wang Q, Wang JZ, Liu GP", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24987368", "url": "https://glygen.org/publication/PubMed/24987368" } ] }, { "title": "Pax6 regulates the expression of Dkk3 in murine and human cell lines, and altered responses to Wnt signaling are shown in FlpIn-3T3 cells stably expressing either the Pax6 or the Pax6(5a) isoform.", "journal": "PloS one", "date": "2014", "authors": "Forsdahl S, Kiselev Y, Hogseth R, Mjelle JE, Mikkola I", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25029272", "url": "https://glygen.org/publication/PubMed/25029272" } ] }, { "title": "GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.", "journal": "eLife", "date": "2014", "authors": "Morgan-Smith M, Wu Y, Zhu X, Pringle J, Snider WD", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25073924", "url": "https://glygen.org/publication/PubMed/25073924" } ] }, { "title": "Activation of \u03b2-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis.", "journal": "Gut", "date": "2015-07", "authors": "Soutto Mohammed, Peng DunFa, Katsha Ahmed, Chen Zheng, Piazuelo Maria Blanca, Washington Mary Kay, Belkhiri Abbes, Correa Pelayo, El-Rifai Wael", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25107557", "url": "https://glygen.org/publication/PubMed/25107557" } ] }, { "title": "Hyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice.", "journal": "Behavioural brain research", "date": "2014", "authors": "Kanno T, Tsuchiya A, Nishizaki T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25172181", "url": "https://glygen.org/publication/PubMed/25172181" } ] }, { "title": "Acute restraint stress impairs induction of long-term potentiation by activating GSK-3beta.", "journal": "Neurochemical research", "date": "2015", "authors": "Jin Y, Kanno T, Nishizaki T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25355398", "url": "https://glygen.org/publication/PubMed/25355398" } ] }, { "title": "Long-term oral exposure to bisphenol A induces glucose intolerance and insulin resistance.", "journal": "The Journal of endocrinology", "date": "2015", "authors": "Moon MK, Jeong IK, Jung Oh T, Ahn HY, Kim HH, Park YJ, Jang HC, Park KS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25972359", "url": "https://glygen.org/publication/PubMed/25972359" } ] }, { "title": "Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3beta signaling pathway.", "journal": "Journal of neurochemistry", "date": "2015", "authors": "Deng J, Habib A, Obregon DF, Barger SW, Giunta B, Wang YJ, Hou H, Sawmiller D, Tan J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26342176", "url": "https://glygen.org/publication/PubMed/26342176" } ] }, { "title": "The synthetic progesterone Norgestrel is neuroprotective in stressed photoreceptor-like cells and retinal explants, mediating its effects via basic fibroblast growth factor, protein kinase A and glycogen synthase kinase 3beta signalling.", "journal": "The European journal of neuroscience", "date": "2016", "authors": "Wyse Jackson AC, Cotter TG", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26750157", "url": "https://glygen.org/publication/PubMed/26750157" } ] }, { "title": "Allosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant Activity.", "journal": "CNS neuroscience & therapeutics", "date": "2016", "authors": "Wang Y, Guo L, Jiang HF, Zheng LT, Zhang A, Zhen XC", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26854125", "url": "https://glygen.org/publication/PubMed/26854125" } ] }, { "title": "CTGF/CCN2 Postconditioning Increases Tolerance of Murine Hearts towards Ischemia-Reperfusion Injury.", "journal": "PloS one", "date": "2016", "authors": "Kaasboll OJ, Moe IT, Ahmed MS, Stang E, Hagelin EM, Attramadal H", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26872261", "url": "https://glygen.org/publication/PubMed/26872261" } ] }, { "title": "Atorvastatin ameliorates cognitive impairment, Abeta1-42 production and Tau hyperphosphorylation in APP/PS1 transgenic mice.", "journal": "Metabolic brain disease", "date": "2016", "authors": "Zhou D, Liu H, Li C, Wang F, Shi Y, Liu L, Zhao X, Liu A, Zhang J, Wang C, Chen Z", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26883430", "url": "https://glygen.org/publication/PubMed/26883430" } ] }, { "title": "Soluble guanylate cyclase activation during ischemic injury in mice protects against postischemic inflammation at the mitochondrial level.", "journal": "American journal of physiology. Gastrointestinal and liver physiology", "date": "2016", "authors": "Wang DZ, Jones AW, Wang WZ, Wang M, Korthuis RJ", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26950856", "url": "https://glygen.org/publication/PubMed/26950856" } ] }, { "title": "Sakuranetin Induces Melanogenesis in B16BL6 Melanoma Cells through Inhibition of ERK and PI3K/AKT Signaling Pathways.", "journal": "Phytotherapy research : PTR", "date": "2016-06", "authors": "Drira Riadh, Sakamoto Kazuichi", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27000529", "url": "https://glygen.org/publication/PubMed/27000529" } ] }, { "title": "Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus.", "journal": "ACS chemical neuroscience", "date": "2016", "authors": "Kohtala S, Theilmann W, Suomi T, Wigren HK, Porkka-Heiskanen T, Elo LL, Rokka A, Rantamaki T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27074656", "url": "https://glygen.org/publication/PubMed/27074656" } ] }, { "title": "Multi-Vitamin B Supplementation Reverses Hypoxia-Induced Tau Hyperphosphorylation and Improves Memory Function in Adult Mice.", "journal": "Journal of Alzheimer's disease : JAD", "date": "2016", "authors": "Yu L, Chen Y, Wang W, Xiao Z, Hong Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27497480", "url": "https://glygen.org/publication/PubMed/27497480" } ] }, { "title": "20-HETE attenuates the response of glucose-stimulated insulin secretion through the AKT/GSK-3beta/Glut2 pathway.", "journal": "Endocrine", "date": "2016", "authors": "Zhang B, Lai G, Wu J, Sun R, Xu R, Yang X, Qi Y, Zhao Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27568038", "url": "https://glygen.org/publication/PubMed/27568038" } ] }, { "title": "Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3beta.", "journal": "Tropical life sciences research", "date": "2016", "authors": "Dahari DE, Salleh RM, Mahmud F, Chin LP, Embi N, Sidek HM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27688851", "url": "https://glygen.org/publication/PubMed/27688851" } ] }, { "title": "Insights on the involvement of (-)-epigallocatechin gallate in ER stress-mediated apoptosis in age-related macular degeneration.", "journal": "Apoptosis : an international journal on programmed cell death", "date": "2017", "authors": "Karthikeyan B, Harini L, Krishnakumar V, Kannan VR, Sundar K, Kathiresan T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27778132", "url": "https://glygen.org/publication/PubMed/27778132" } ] }, { "title": "Tetramethylpyrazine Analogue CXC195 Protects Against Dopaminergic Neuronal Apoptosis via Activation of PI3K/Akt/GSK3beta Signaling Pathway in 6-OHDA-Induced Parkinson's Disease Mice.", "journal": "Neurochemical research", "date": "2017", "authors": "Chen L, Cheng L, Wei X, Yuan Z, Wu Y, Wang S, Ren Z, Liu X, Liu H", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28005221", "url": "https://glygen.org/publication/PubMed/28005221" } ] }, { "title": "Infiltrating mast cells promote renal cell carcinoma angiogenesis by modulating PI3K-->AKT-->GSK3beta-->AM signaling.", "journal": "Oncogene", "date": "2017", "authors": "Chen Y, Li C, Xie H, Fan Y, Yang Z, Ma J, He D, Li L", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28114284", "url": "https://glygen.org/publication/PubMed/28114284" } ] }, { "title": "The Antimalarial Effect of Curcumin Is Mediated by the Inhibition of Glycogen Synthase Kinase-3beta.", "journal": "Journal of medicinal food", "date": "2017", "authors": "Ali AH, Sudi S, Basir R, Embi N, Sidek HM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28146408", "url": "https://glygen.org/publication/PubMed/28146408" } ] }, { "title": "Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice.", "journal": "Frontiers in molecular neuroscience", "date": "2017", "authors": "Wang Zigao, Xiong Lu, Wan Wenbin, Duan Lijie, Bai Xiaojing, Zu Hengbing", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28228716", "url": "https://glygen.org/publication/PubMed/28228716" } ] }, { "title": "Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3beta-dependent increases in mitochondrial membrane permeability.", "journal": "Oncotarget", "date": "2017", "authors": "Zhou X, Wang HY, Wu B, Cheng CY, Xiao W, Wang ZZ, Yang YY, Li P, Yang H", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28591721", "url": "https://glygen.org/publication/PubMed/28591721" } ] }, { "title": "Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma.", "journal": "Gastroenterology", "date": "2017", "authors": "Xie Y, Zhu S, Zhong M, Yang M, Sun X, Liu J, Kroemer G, Lotze M, Zeh HJ 3rd, Kang R, Tang D", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28764929", "url": "https://glygen.org/publication/PubMed/28764929" } ] }, { "title": "Failure to Inactivate Nuclear GSK3beta by Ser(389)-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response.", "journal": "Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology", "date": "2018", "authors": "Thornton TM, Hare B, Colie S, Pendlebury WW, Nebreda AR, Falls W, Jaworski DM, Rincon M", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28832021", "url": "https://glygen.org/publication/PubMed/28832021" } ] }, { "title": "Prenatal Alcohol Exposure Leads to Enhanced Serine 9 Phosphorylation of Glycogen Synthase Kinase-3\u03b2 (GSK-3\u03b2) in the Hippocampal Dentate Gyrus of Adult Mouse.", "journal": "Alcoholism, clinical and experimental research", "date": "2017-11", "authors": "Cunningham Lee Anna, Newville Jessie, Li Lu, Tapia Phillip, Allan Andrea M, Valenzuela C Fernando", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28865114", "url": "https://glygen.org/publication/PubMed/28865114" } ] }, { "title": "Loss of protein phosphatase 2A regulatory subunit B56delta promotes spontaneous tumorigenesis in vivo.", "journal": "Oncogene", "date": "2018", "authors": "Lambrecht C, Libbrecht L, Sagaert X, Pauwels P, Hoorne Y, Crowther J, Louis JV, Sents W, Sablina A, Janssens V", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28967903", "url": "https://glygen.org/publication/PubMed/28967903" } ] }, { "title": "Dihydromyricetin exerts a rapid antidepressant-like effect in association with enhancement of BDNF expression and inhibition of neuroinflammation.", "journal": "Psychopharmacology", "date": "2018-01", "authors": "Ren Zhaoxiang, Yan Pengju, Zhu Liushuai, Yang Huicui, Zhao Yafei, Kirby Brian P, Waddington John L, Zhen Xuechu", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29058041", "url": "https://glygen.org/publication/PubMed/29058041" } ] }, { "title": "BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3beta.", "journal": "Cellular and molecular life sciences : CMLS", "date": "2018", "authors": "Golick L, Han Y, Kim Y, Park SW", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29127434", "url": "https://glygen.org/publication/PubMed/29127434" } ] }, { "title": "Inositol polyphosphates contribute to cellular circadian rhythms: Implications for understanding lithium's molecular mechanism.", "journal": "Cellular signalling", "date": "2018", "authors": "Wei H, Landgraf D, Wang G, McCarthy MJ", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29331582", "url": "https://glygen.org/publication/PubMed/29331582" } ] }, { "title": "Influence of sevoflurane exposure on mitogen-activated protein kinases and Akt/GSK-3beta/CRMP-2 signaling pathways in the developing rat brain.", "journal": "Experimental and therapeutic medicine", "date": "2018", "authors": "Liu Y, Liu C, Zeng M, Han X, Zhang K, Fu Y, Li J, Li Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29434807", "url": "https://glygen.org/publication/PubMed/29434807" } ] }, { "title": "Glycogen synthase kinase 3beta promotes liver innate immune activation by restraining AMP-activated protein kinase activation.", "journal": "Journal of hepatology", "date": "2018", "authors": "Zhou H, Wang H, Ni M, Yue S, Xia Y, Busuttil RW, Kupiec-Weglinski JW, Lu L, Wang X, Zhai Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29452207", "url": "https://glygen.org/publication/PubMed/29452207" } ] }, { "title": "SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation.", "journal": "eLife", "date": "2018", "authors": "Sarikhani M, Mishra S, Maity S, Kotyada C, Wolfgeher D, Gupta MP, Singh M, Sundaresan NR", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29504933", "url": "https://glygen.org/publication/PubMed/29504933" } ] }, { "title": "Seipin deficiency in mice causes loss of dopaminergic neurons via aggregation and phosphorylation of alpha-synuclein and neuroinflammation.", "journal": "Cell death & disease", "date": "2018", "authors": "Wang L, Hong J, Wu Y, Liu G, Yu W, Chen L", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29670081", "url": "https://glygen.org/publication/PubMed/29670081" } ] }, { "title": "Antidepressant effects of creatine on amyloid beta1-40-treated mice: The role of GSK-3beta/Nrf2 pathway.", "journal": "Progress in neuro-psychopharmacology & biological psychiatry", "date": "2018", "authors": "Rosa JM, Pazini FL, Cunha MP, Colla ARS, Manosso LM, Mancini G, Souza ACG, de Bem AF, Prediger RD, Rodrigues ALS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29753049", "url": "https://glygen.org/publication/PubMed/29753049" } ] }, { "title": "Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy.", "journal": "Oxidative medicine and cellular longevity", "date": "2018", "authors": "Jaskiewicz A, Pajak B, Litwiniuk A, Urbanska K, Orzechowski A", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29951166", "url": "https://glygen.org/publication/PubMed/29951166" } ] }, { "title": "Protective Effects of 6-(Methylsulfinyl)hexyl Isothiocyanate on Abeta1-42-Induced Cognitive Deficit, Oxidative Stress, Inflammation, and Apoptosis in Mice.", "journal": "International journal of molecular sciences", "date": "2018", "authors": "Morroni F, Sita G, Graziosi A, Turrini E, Fimognari C, Tarozzi A, Hrelia P", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "30021941", "url": "https://glygen.org/publication/PubMed/30021941" } ] }, { "title": "Enrichment of cancer stem cells via beta-catenin contributing to the tumorigenesis of hepatocellular carcinoma.", "journal": "BMC cancer", "date": "2018", "authors": "Pandit H, Li Y, Li X, Zhang W, Li S, Martin RCG", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "30075764", "url": "https://glygen.org/publication/PubMed/30075764" } ] }, { "title": "Myostatin inhibits glucose uptake via suppression of insulin-dependent and -independent signaling pathways in myoblasts.", "journal": "Physiological reports", "date": "2018", "authors": "Liu XH, Bauman WA, Cardozo CP", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "30252210", "url": "https://glygen.org/publication/PubMed/30252210" } ] }, { "title": "The PI3K/Akt/GSK-3beta/ROS/eIF2B pathway promotes breast cancer growth and metastasis via suppression of NK cell cytotoxicity and tumor cell susceptibility.", "journal": "Cancer biology & medicine", "date": "2019", "authors": "Jin F, Wu Z, Hu X, Zhang J, Gao Z, Han X, Qin J, Li C, Wang Y", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31119045", "url": "https://glygen.org/publication/PubMed/31119045" } ] }, { "title": "Adenosine N1-Oxide Exerts Anti-inflammatory Effects through the PI3K/Akt/GSK-3beta Signaling Pathway and Promotes Osteogenic and Adipocyte Differentiation.", "journal": "Biological & pharmaceutical bulletin", "date": "2019", "authors": "Ohashi E, Kohno K, Arai N, Harashima A, Ariyasu T, Ushio S", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31155593", "url": "https://glygen.org/publication/PubMed/31155593" } ] }, { "title": "Adiponectin improves long-term potentiation in the 5XFAD mouse brain.", "journal": "Scientific reports", "date": "2019", "authors": "Wang M, Jo J, Song J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31222110", "url": "https://glygen.org/publication/PubMed/31222110" } ] }, { "title": "Isorhynchophylline exerts antidepressant-like effects in mice via modulating neuroinflammation and neurotrophins: involvement of the PI3K/Akt/GSK-3beta signaling pathway.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2019", "authors": "Xian YF, Ip SP, Li HQ, Qu C, Su ZR, Chen JN, Lin ZX", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31233346", "url": "https://glygen.org/publication/PubMed/31233346" } ] }, { "title": "Innate sensitivity to stress facilitates inflammation, alters metabolism and shortens lifespan in a mouse model of social hierarchy.", "journal": "Aging", "date": "2019-11-09", "authors": "Bairachnaya Maryia, Agranyoni Oryan, Antoch Marina, Michaelevski Izhak, Pinhasov Albert", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31707362", "url": "https://glygen.org/publication/PubMed/31707362" } ] }, { "title": "Dopamine D3 receptor and GSK3beta signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice.", "journal": "Journal of biomedical science", "date": "2020", "authors": "Chang PK, Chu J, Tsai YT, Lai YH, Chen JC", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31900153", "url": "https://glygen.org/publication/PubMed/31900153" } ] }, { "title": "Pharmacological Chaperones Attenuate the Development of Opioid Tolerance.", "journal": "International journal of molecular sciences", "date": "2020-10-13", "authors": "Okuyama Youta, Jin Hisayo, Kokubun Hiroshi, Aoe Tomohiko", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "33066035", "url": "https://glygen.org/publication/PubMed/33066035" } ] }, { "title": "\u03b2\u2011Lapachone ameliorates L\u2011DOPA\u2011induced dyskinesia in\u00a0a\u00a06\u2011OHDA\u2011induced mouse model of Parkinson's disease.", "journal": "Molecular medicine reports", "date": "2021-03", "authors": "Ryu Young-Kyoung, Park Hye-Yeon, Go Jun, Lee In-Bok, Choi Young-Keun, Lee Chul-Ho, Kim Kyoung-Shim", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "33495840", "url": "https://glygen.org/publication/PubMed/33495840" } ] }, { "title": "Silencing of Sphingosine kinase 1 Affects Maturation Pathways in Mouse Neonatal Cardiomyocytes.", "journal": "International journal of molecular sciences", "date": "2021-03-31", "authors": "Jozefczuk Ewelina, Szczepaniak Piotr, Guzik Tomasz Jan, Siedlinski Mateusz", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "33807180", "url": "https://glygen.org/publication/PubMed/33807180" } ] }, { "title": "Neuroprotective Effect of E3 Ubiquitin Ligase RNF8 Against Ischemic Stroke via HDAC2 Stability Reduction and Reelin-Dependent GSK3beta Inhibition.", "journal": "Molecular neurobiology", "date": "2022", "authors": "Zhu X, Li J, You D, Xiao Y, Huang Z, Yu W", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "35622272", "url": "https://glygen.org/publication/PubMed/35622272" } ] }, { "title": "A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 \u03b6.", "journal": "Journal of ginseng research", "date": "2022-09", "authors": "Chen Lin, Li Ruimei, Chen Feiyan, Zhang Hantao, Zhu Zhu, Xu Shuyi, Cheng Yao, Zhao Yunan", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "36090685", "url": "https://glygen.org/publication/PubMed/36090685" } ] }, { "title": "Systemic TM4SF5 overexpression in ApcMin/+ mice promotes hepatic portal hypertension associated with fibrosis.", "journal": "BMB reports", "date": "2022-12", "authors": "Lee Joohyeong, Kim Eunmi, Kang Min-Kyung, Ryu Jihye, Kim Ji Eon, Shin Eun-Ae, Pinanga Yangie, Pyo Kyung-Hee, Lee Haesong, Lee Eun Hae, Cho Heejin, Cheon Jayeon, Kim Wonsik, Jho Eek-Hoon, Kim Semi, Lee Jung Weon", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "36104259", "url": "https://glygen.org/publication/PubMed/36104259" } ] }, { "title": "Glucose sensor O-GlcNAcylation coordinates with phosphorylation to regulate circadian clock.", "journal": "Cell metabolism", "date": "2013", "authors": "Kaasik K, Kivimae S, Allen JJ, Chalkley RJ, Huang Y, Baer K, Kissel H, Burlingame AL, Shokat KM, Ptacek LJ, Fu YH", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23395175", "url": "https://glygen.org/publication/PubMed/23395175" } ] }, { "title": "Glycogen synthase kinase-3beta stabilizes the interleukin (IL)-22 receptor from proteasomal degradation in murine lung epithelia.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Weathington NM, Snavely CA, Chen BB, Zhao J, Zhao Y, Mallampalli RK", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24742671", "url": "https://glygen.org/publication/PubMed/24742671" } ] }, { "title": "Control of diabetic hyperglycaemia and insulin resistance through TSC22D4.", "journal": "Nature communications", "date": "2016", "authors": "Ekim Ustunel B, Friedrich K, Maida A, Wang X, Krones-Herzig A, Seibert O, Sommerfeld A, Jones A, Sijmonsma TP, Sticht C, Gretz N, Fleming T, Nawroth PP, Stremmel W, Rose AJ, Berriel-Diaz M, Bluher M, Herzig S", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27827363", "url": "https://glygen.org/publication/PubMed/27827363" } ] } ], "crossref": [ { "id": "31409917", "url": "https://glygen.org/publication/PubMed/31409917", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14749383", "url": "https://glygen.org/publication/PubMed/14749383", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11959983", "url": "https://glygen.org/publication/PubMed/11959983", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37033243", "url": "https://glygen.org/publication/PubMed/37033243", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15791206", "url": "https://glygen.org/publication/PubMed/15791206", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22057101", "url": "https://glygen.org/publication/PubMed/22057101", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "28646232", "url": "https://glygen.org/publication/PubMed/28646232", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9WV60", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q9WV60", "database": "PRO", "categories": [ "Other" ] }, { "id": "16522636", "url": "https://glygen.org/publication/PubMed/16522636", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26582204", "url": "https://glygen.org/publication/PubMed/26582204", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12095987", "url": "https://glygen.org/publication/PubMed/12095987", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12489109", "url": "https://glygen.org/publication/PubMed/12489109", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12504922", "url": "https://glygen.org/publication/PubMed/12504922", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14745448", "url": "https://glygen.org/publication/PubMed/14745448", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15039769", "url": "https://glygen.org/publication/PubMed/15039769", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15659239", "url": "https://glygen.org/publication/PubMed/15659239", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15878878", "url": "https://glygen.org/publication/PubMed/15878878", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15888552", "url": "https://glygen.org/publication/PubMed/15888552", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15980066", "url": "https://glygen.org/publication/PubMed/15980066", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16039605", "url": "https://glygen.org/publication/PubMed/16039605", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16374520", "url": "https://glygen.org/publication/PubMed/16374520", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16434614", "url": "https://glygen.org/publication/PubMed/16434614", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16489037", "url": "https://glygen.org/publication/PubMed/16489037", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16501492", "url": "https://glygen.org/publication/PubMed/16501492", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16510873", "url": "https://glygen.org/publication/PubMed/16510873", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16530186", "url": "https://glygen.org/publication/PubMed/16530186", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16565488", "url": "https://glygen.org/publication/PubMed/16565488", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16762022", "url": "https://glygen.org/publication/PubMed/16762022", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16941690", "url": "https://glygen.org/publication/PubMed/16941690", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16954147", "url": "https://glygen.org/publication/PubMed/16954147", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16987252", "url": "https://glygen.org/publication/PubMed/16987252", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17053159", "url": "https://glygen.org/publication/PubMed/17053159", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17241269", "url": "https://glygen.org/publication/PubMed/17241269", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17475833", "url": "https://glygen.org/publication/PubMed/17475833", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17560576", "url": "https://glygen.org/publication/PubMed/17560576", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17714451", "url": "https://glygen.org/publication/PubMed/17714451", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17975737", "url": "https://glygen.org/publication/PubMed/17975737", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18322105", "url": "https://glygen.org/publication/PubMed/18322105", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18701453", "url": "https://glygen.org/publication/PubMed/18701453", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18801732", "url": "https://glygen.org/publication/PubMed/18801732", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18824542", "url": "https://glygen.org/publication/PubMed/18824542", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19011050", "url": "https://glygen.org/publication/PubMed/19011050", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19070648", "url": "https://glygen.org/publication/PubMed/19070648", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19106302", "url": "https://glygen.org/publication/PubMed/19106302", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19126599", "url": "https://glygen.org/publication/PubMed/19126599", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19328817", "url": "https://glygen.org/publication/PubMed/19328817", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19356803", "url": "https://glygen.org/publication/PubMed/19356803", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19379814", "url": "https://glygen.org/publication/PubMed/19379814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19818092", "url": "https://glygen.org/publication/PubMed/19818092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19939226", "url": "https://glygen.org/publication/PubMed/19939226", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20111716", "url": "https://glygen.org/publication/PubMed/20111716", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20332342", "url": "https://glygen.org/publication/PubMed/20332342", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20592205", "url": "https://glygen.org/publication/PubMed/20592205", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20690801", "url": "https://glygen.org/publication/PubMed/20690801", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21079728", "url": "https://glygen.org/publication/PubMed/21079728", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21540081", "url": "https://glygen.org/publication/PubMed/21540081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21544852", "url": "https://glygen.org/publication/PubMed/21544852", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21659643", "url": "https://glygen.org/publication/PubMed/21659643", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21671257", "url": "https://glygen.org/publication/PubMed/21671257", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21821713", "url": "https://glygen.org/publication/PubMed/21821713", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21998135", "url": "https://glygen.org/publication/PubMed/21998135", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22019984", "url": "https://glygen.org/publication/PubMed/22019984", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22022450", "url": "https://glygen.org/publication/PubMed/22022450", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22064483", "url": "https://glygen.org/publication/PubMed/22064483", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22238573", "url": "https://glygen.org/publication/PubMed/22238573", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22434044", "url": "https://glygen.org/publication/PubMed/22434044", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22471389", "url": "https://glygen.org/publication/PubMed/22471389", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22672822", "url": "https://glygen.org/publication/PubMed/22672822", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22714712", "url": "https://glygen.org/publication/PubMed/22714712", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23051669", "url": "https://glygen.org/publication/PubMed/23051669", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23239877", "url": "https://glygen.org/publication/PubMed/23239877", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23301857", "url": "https://glygen.org/publication/PubMed/23301857", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23324178", "url": "https://glygen.org/publication/PubMed/23324178", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23369342", "url": "https://glygen.org/publication/PubMed/23369342", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23444402", "url": "https://glygen.org/publication/PubMed/23444402", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23455548", "url": "https://glygen.org/publication/PubMed/23455548", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23807397", "url": "https://glygen.org/publication/PubMed/23807397", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23816813", "url": "https://glygen.org/publication/PubMed/23816813", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23853095", "url": "https://glygen.org/publication/PubMed/23853095", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24025512", "url": "https://glygen.org/publication/PubMed/24025512", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24227739", "url": "https://glygen.org/publication/PubMed/24227739", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24278135", "url": "https://glygen.org/publication/PubMed/24278135", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24462873", "url": "https://glygen.org/publication/PubMed/24462873", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24670930", "url": "https://glygen.org/publication/PubMed/24670930", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24675832", "url": "https://glygen.org/publication/PubMed/24675832", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788685", "url": "https://glygen.org/publication/PubMed/24788685", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24969778", "url": "https://glygen.org/publication/PubMed/24969778", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24983010", "url": "https://glygen.org/publication/PubMed/24983010", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24987368", "url": "https://glygen.org/publication/PubMed/24987368", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25029272", "url": "https://glygen.org/publication/PubMed/25029272", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25073924", "url": "https://glygen.org/publication/PubMed/25073924", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25107557", "url": "https://glygen.org/publication/PubMed/25107557", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25172181", "url": "https://glygen.org/publication/PubMed/25172181", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25355398", "url": "https://glygen.org/publication/PubMed/25355398", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25972359", "url": "https://glygen.org/publication/PubMed/25972359", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26342176", "url": "https://glygen.org/publication/PubMed/26342176", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26750157", "url": "https://glygen.org/publication/PubMed/26750157", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26854125", "url": "https://glygen.org/publication/PubMed/26854125", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26872261", "url": "https://glygen.org/publication/PubMed/26872261", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26883430", "url": "https://glygen.org/publication/PubMed/26883430", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26950856", "url": "https://glygen.org/publication/PubMed/26950856", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27000529", "url": "https://glygen.org/publication/PubMed/27000529", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27074656", "url": "https://glygen.org/publication/PubMed/27074656", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27497480", "url": "https://glygen.org/publication/PubMed/27497480", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27568038", "url": "https://glygen.org/publication/PubMed/27568038", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27688851", "url": "https://glygen.org/publication/PubMed/27688851", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27778132", "url": "https://glygen.org/publication/PubMed/27778132", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28005221", "url": "https://glygen.org/publication/PubMed/28005221", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28114284", "url": "https://glygen.org/publication/PubMed/28114284", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28146408", "url": "https://glygen.org/publication/PubMed/28146408", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28228716", "url": "https://glygen.org/publication/PubMed/28228716", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28591721", "url": "https://glygen.org/publication/PubMed/28591721", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28764929", "url": "https://glygen.org/publication/PubMed/28764929", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28832021", "url": "https://glygen.org/publication/PubMed/28832021", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28865114", "url": "https://glygen.org/publication/PubMed/28865114", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28967903", "url": "https://glygen.org/publication/PubMed/28967903", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29058041", "url": "https://glygen.org/publication/PubMed/29058041", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29127434", "url": "https://glygen.org/publication/PubMed/29127434", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29331582", "url": "https://glygen.org/publication/PubMed/29331582", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29434807", "url": "https://glygen.org/publication/PubMed/29434807", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29452207", "url": "https://glygen.org/publication/PubMed/29452207", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29504933", "url": "https://glygen.org/publication/PubMed/29504933", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29670081", "url": "https://glygen.org/publication/PubMed/29670081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29753049", "url": "https://glygen.org/publication/PubMed/29753049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29951166", "url": "https://glygen.org/publication/PubMed/29951166", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30021941", "url": "https://glygen.org/publication/PubMed/30021941", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30075764", "url": "https://glygen.org/publication/PubMed/30075764", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30252210", "url": "https://glygen.org/publication/PubMed/30252210", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31119045", "url": "https://glygen.org/publication/PubMed/31119045", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31155593", "url": "https://glygen.org/publication/PubMed/31155593", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31222110", "url": "https://glygen.org/publication/PubMed/31222110", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31233346", "url": "https://glygen.org/publication/PubMed/31233346", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31707362", "url": "https://glygen.org/publication/PubMed/31707362", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31900153", "url": "https://glygen.org/publication/PubMed/31900153", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33066035", "url": "https://glygen.org/publication/PubMed/33066035", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33495840", "url": "https://glygen.org/publication/PubMed/33495840", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33807180", "url": "https://glygen.org/publication/PubMed/33807180", "database": "PubMed", "categories": [ "Other" ] }, { "id": "35622272", "url": "https://glygen.org/publication/PubMed/35622272", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36090685", "url": "https://glygen.org/publication/PubMed/36090685", "database": "PubMed", "categories": [ "Other" ] }, { "id": "36104259", "url": "https://glygen.org/publication/PubMed/36104259", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23395175", "url": "https://glygen.org/publication/PubMed/23395175", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24742671", "url": "https://glygen.org/publication/PubMed/24742671", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27827363", "url": "https://glygen.org/publication/PubMed/27827363", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSGRPRTT", "down_seq": "FAESCKPVQQPSAFGSMKVS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser9", "evidence": [ { "id": "31409917", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/31409917" }, { "id": "Q9WV60", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WV60" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "14749383", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/14749383" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "11959983", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11959983" }, { "id": "37033243", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37033243" } ] } ], "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation; No inhibition of activity and constitutively active.", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "PubMed", "id": "15791206", "url": "https://glygen.org/publication/PubMed/15791206" }, { "database": "PubMed", "id": "22057101", "url": "https://glygen.org/publication/PubMed/22057101" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "P63085-1", "kinase_gene_name": "Mapk1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "28646232", "url": "https://glygen.org/publication/PubMed/28646232" } ], "site_lbl": "Ser9" }, { "kinase_uniprot_canonical_ac": "Q63844-1", "kinase_gene_name": "Mapk3", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "28646232", "url": "https://glygen.org/publication/PubMed/28646232" } ], "site_lbl": "Ser9" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKB/AKT1, RPS6KA3, SGK3 and NME7", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "PRO", "id": "Q9WV60", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "16522636", "url": "https://glygen.org/publication/PubMed/16522636" }, { "database": "PubMed", "id": "26582204", "url": "https://glygen.org/publication/PubMed/26582204" }, { "database": "PubMed", "id": "12095987", "url": "https://glygen.org/publication/PubMed/12095987" }, { "database": "PubMed", "id": "12489109", "url": "https://glygen.org/publication/PubMed/12489109" }, { "database": "PubMed", "id": "12504922", "url": "https://glygen.org/publication/PubMed/12504922" }, { "database": "PubMed", "id": "14745448", "url": "https://glygen.org/publication/PubMed/14745448" }, { "database": "PubMed", "id": "15039769", "url": "https://glygen.org/publication/PubMed/15039769" }, { "database": "PubMed", "id": "15659239", "url": "https://glygen.org/publication/PubMed/15659239" }, { "database": "PubMed", "id": "15878878", "url": "https://glygen.org/publication/PubMed/15878878" }, { "database": "PubMed", "id": "15888552", "url": "https://glygen.org/publication/PubMed/15888552" }, { "database": "PubMed", "id": "15980066", "url": "https://glygen.org/publication/PubMed/15980066" }, { "database": "PubMed", "id": "16039605", "url": "https://glygen.org/publication/PubMed/16039605" }, { "database": "PubMed", "id": "16374520", "url": "https://glygen.org/publication/PubMed/16374520" }, { "database": "PubMed", "id": "16434614", "url": "https://glygen.org/publication/PubMed/16434614" }, { "database": "PubMed", "id": "16489037", "url": "https://glygen.org/publication/PubMed/16489037" }, { "database": "PubMed", "id": "16501492", "url": "https://glygen.org/publication/PubMed/16501492" }, { "database": "PubMed", "id": "16510873", "url": "https://glygen.org/publication/PubMed/16510873" }, { "database": "PubMed", "id": "16530186", "url": "https://glygen.org/publication/PubMed/16530186" }, { "database": "PubMed", "id": "16565488", "url": "https://glygen.org/publication/PubMed/16565488" }, { "database": "PubMed", "id": "16762022", "url": "https://glygen.org/publication/PubMed/16762022" }, { "database": "PubMed", "id": "16941690", "url": "https://glygen.org/publication/PubMed/16941690" }, { "database": "PubMed", "id": "16954147", "url": "https://glygen.org/publication/PubMed/16954147" }, { "database": "PubMed", "id": "16987252", "url": "https://glygen.org/publication/PubMed/16987252" }, { "database": "PubMed", "id": "17053159", "url": "https://glygen.org/publication/PubMed/17053159" }, { "database": "PubMed", "id": "17241269", "url": "https://glygen.org/publication/PubMed/17241269" }, { "database": "PubMed", "id": "17475833", "url": "https://glygen.org/publication/PubMed/17475833" }, { "database": "PubMed", "id": "17560576", "url": "https://glygen.org/publication/PubMed/17560576" }, { "database": "PubMed", "id": "17714451", "url": "https://glygen.org/publication/PubMed/17714451" }, { "database": "PubMed", "id": "17975737", "url": "https://glygen.org/publication/PubMed/17975737" }, { "database": "PubMed", "id": "18322105", "url": "https://glygen.org/publication/PubMed/18322105" }, { "database": "PubMed", "id": "18701453", "url": "https://glygen.org/publication/PubMed/18701453" }, { "database": "PubMed", "id": "18801732", "url": "https://glygen.org/publication/PubMed/18801732" }, { "database": "PubMed", "id": "18824542", "url": "https://glygen.org/publication/PubMed/18824542" }, { "database": "PubMed", "id": "19011050", "url": "https://glygen.org/publication/PubMed/19011050" }, { "database": "PubMed", "id": "19070648", "url": "https://glygen.org/publication/PubMed/19070648" }, { "database": "PubMed", "id": "19106302", "url": "https://glygen.org/publication/PubMed/19106302" }, { "database": "PubMed", "id": "19126599", "url": "https://glygen.org/publication/PubMed/19126599" }, { "database": "PubMed", "id": "19328817", "url": "https://glygen.org/publication/PubMed/19328817" }, { "database": "PubMed", "id": "19356803", "url": "https://glygen.org/publication/PubMed/19356803" }, { "database": "PubMed", "id": "19379814", "url": "https://glygen.org/publication/PubMed/19379814" }, { "database": "PubMed", "id": "19818092", "url": "https://glygen.org/publication/PubMed/19818092" }, { "database": "PubMed", "id": "19939226", "url": "https://glygen.org/publication/PubMed/19939226" }, { "database": "PubMed", "id": "20111716", "url": "https://glygen.org/publication/PubMed/20111716" }, { "database": "PubMed", "id": "20332342", "url": "https://glygen.org/publication/PubMed/20332342" }, { "database": "PubMed", "id": "20592205", "url": "https://glygen.org/publication/PubMed/20592205" }, { "database": "PubMed", "id": "20690801", "url": "https://glygen.org/publication/PubMed/20690801" }, { "database": "PubMed", "id": "21079728", "url": "https://glygen.org/publication/PubMed/21079728" }, { "database": "PubMed", "id": "21540081", "url": "https://glygen.org/publication/PubMed/21540081" }, { "database": "PubMed", "id": "21544852", "url": "https://glygen.org/publication/PubMed/21544852" }, { "database": "PubMed", "id": "21659643", "url": "https://glygen.org/publication/PubMed/21659643" }, { "database": "PubMed", "id": "21671257", "url": "https://glygen.org/publication/PubMed/21671257" }, { "database": "PubMed", "id": "21821713", "url": "https://glygen.org/publication/PubMed/21821713" }, { "database": "PubMed", "id": "21998135", "url": "https://glygen.org/publication/PubMed/21998135" }, { "database": "PubMed", "id": "22019984", "url": "https://glygen.org/publication/PubMed/22019984" }, { "database": "PubMed", "id": "22022450", "url": "https://glygen.org/publication/PubMed/22022450" }, { "database": "PubMed", "id": "22064483", "url": "https://glygen.org/publication/PubMed/22064483" }, { "database": "PubMed", "id": "22238573", "url": "https://glygen.org/publication/PubMed/22238573" }, { "database": "PubMed", "id": "22434044", "url": "https://glygen.org/publication/PubMed/22434044" }, { "database": "PubMed", "id": "22471389", "url": "https://glygen.org/publication/PubMed/22471389" }, { "database": "PubMed", "id": "22672822", "url": "https://glygen.org/publication/PubMed/22672822" }, { "database": "PubMed", "id": "22714712", "url": "https://glygen.org/publication/PubMed/22714712" }, { "database": "PubMed", "id": "23051669", "url": "https://glygen.org/publication/PubMed/23051669" }, { "database": "PubMed", "id": "23239877", "url": "https://glygen.org/publication/PubMed/23239877" }, { "database": "PubMed", "id": "23301857", "url": "https://glygen.org/publication/PubMed/23301857" }, { "database": "PubMed", "id": "23324178", "url": "https://glygen.org/publication/PubMed/23324178" }, { "database": "PubMed", "id": "23369342", "url": "https://glygen.org/publication/PubMed/23369342" }, { "database": "PubMed", "id": "23444402", "url": "https://glygen.org/publication/PubMed/23444402" }, { "database": "PubMed", "id": "23455548", "url": "https://glygen.org/publication/PubMed/23455548" }, { "database": "PubMed", "id": "23807397", "url": "https://glygen.org/publication/PubMed/23807397" }, { "database": "PubMed", "id": "23816813", "url": "https://glygen.org/publication/PubMed/23816813" }, { "database": "PubMed", "id": "23853095", "url": "https://glygen.org/publication/PubMed/23853095" }, { "database": "PubMed", "id": "24025512", "url": "https://glygen.org/publication/PubMed/24025512" }, { "database": "PubMed", "id": "24227739", "url": "https://glygen.org/publication/PubMed/24227739" }, { "database": "PubMed", "id": "24278135", "url": "https://glygen.org/publication/PubMed/24278135" }, { "database": "PubMed", "id": "24462873", "url": "https://glygen.org/publication/PubMed/24462873" }, { "database": "PubMed", "id": "24670930", "url": "https://glygen.org/publication/PubMed/24670930" }, { "database": "PubMed", "id": "24675832", "url": "https://glygen.org/publication/PubMed/24675832" }, { "database": "PubMed", "id": "24788685", "url": "https://glygen.org/publication/PubMed/24788685" }, { "database": "PubMed", "id": "24969778", "url": "https://glygen.org/publication/PubMed/24969778" }, { "database": "PubMed", "id": "24983010", "url": "https://glygen.org/publication/PubMed/24983010" }, { "database": "PubMed", "id": "24987368", "url": "https://glygen.org/publication/PubMed/24987368" }, { "database": "PubMed", "id": "25029272", "url": "https://glygen.org/publication/PubMed/25029272" }, { "database": "PubMed", "id": "25073924", "url": "https://glygen.org/publication/PubMed/25073924" }, { "database": "PubMed", "id": "25107557", "url": "https://glygen.org/publication/PubMed/25107557" }, { "database": "PubMed", "id": "25172181", "url": "https://glygen.org/publication/PubMed/25172181" }, { "database": "PubMed", "id": "25355398", "url": "https://glygen.org/publication/PubMed/25355398" }, { "database": "PubMed", "id": "25972359", "url": "https://glygen.org/publication/PubMed/25972359" }, { "database": "PubMed", "id": "26342176", "url": "https://glygen.org/publication/PubMed/26342176" }, { "database": "PubMed", "id": "26750157", "url": "https://glygen.org/publication/PubMed/26750157" }, { "database": "PubMed", "id": "26854125", "url": "https://glygen.org/publication/PubMed/26854125" }, { "database": "PubMed", "id": "26872261", "url": "https://glygen.org/publication/PubMed/26872261" }, { "database": "PubMed", "id": "26883430", "url": "https://glygen.org/publication/PubMed/26883430" }, { "database": "PubMed", "id": "26950856", "url": "https://glygen.org/publication/PubMed/26950856" }, { "database": "PubMed", "id": "27000529", "url": "https://glygen.org/publication/PubMed/27000529" }, { "database": "PubMed", "id": "27074656", "url": "https://glygen.org/publication/PubMed/27074656" }, { "database": "PubMed", "id": "27497480", "url": "https://glygen.org/publication/PubMed/27497480" }, { "database": "PubMed", "id": "27568038", "url": "https://glygen.org/publication/PubMed/27568038" }, { "database": "PubMed", "id": "27688851", "url": "https://glygen.org/publication/PubMed/27688851" }, { "database": "PubMed", "id": "27778132", "url": "https://glygen.org/publication/PubMed/27778132" }, { "database": "PubMed", "id": "28005221", "url": "https://glygen.org/publication/PubMed/28005221" }, { "database": "PubMed", "id": "28114284", "url": "https://glygen.org/publication/PubMed/28114284" }, { "database": "PubMed", "id": "28146408", "url": "https://glygen.org/publication/PubMed/28146408" }, { "database": "PubMed", "id": "28228716", "url": "https://glygen.org/publication/PubMed/28228716" }, { "database": "PubMed", "id": "28591721", "url": "https://glygen.org/publication/PubMed/28591721" }, { "database": "PubMed", "id": "28764929", "url": "https://glygen.org/publication/PubMed/28764929" }, { "database": "PubMed", "id": "28832021", "url": "https://glygen.org/publication/PubMed/28832021" }, { "database": "PubMed", "id": "28865114", "url": "https://glygen.org/publication/PubMed/28865114" }, { "database": "PubMed", "id": "28967903", "url": "https://glygen.org/publication/PubMed/28967903" }, { "database": "PubMed", "id": "29058041", "url": "https://glygen.org/publication/PubMed/29058041" }, { "database": "PubMed", "id": "29127434", "url": "https://glygen.org/publication/PubMed/29127434" }, { "database": "PubMed", "id": "29331582", "url": "https://glygen.org/publication/PubMed/29331582" }, { "database": "PubMed", "id": "29434807", "url": "https://glygen.org/publication/PubMed/29434807" }, { "database": "PubMed", "id": "29452207", "url": "https://glygen.org/publication/PubMed/29452207" }, { "database": "PubMed", "id": "29504933", "url": "https://glygen.org/publication/PubMed/29504933" }, { "database": "PubMed", "id": "29670081", "url": "https://glygen.org/publication/PubMed/29670081" }, { "database": "PubMed", "id": "29753049", "url": "https://glygen.org/publication/PubMed/29753049" }, { "database": "PubMed", "id": "29951166", "url": "https://glygen.org/publication/PubMed/29951166" }, { "database": "PubMed", "id": "30021941", "url": "https://glygen.org/publication/PubMed/30021941" }, { "database": "PubMed", "id": "30075764", "url": "https://glygen.org/publication/PubMed/30075764" }, { "database": "PubMed", "id": "30252210", "url": "https://glygen.org/publication/PubMed/30252210" }, { "database": "PubMed", "id": "31119045", "url": "https://glygen.org/publication/PubMed/31119045" }, { "database": "PubMed", "id": "31155593", "url": "https://glygen.org/publication/PubMed/31155593" }, { "database": "PubMed", "id": "31222110", "url": "https://glygen.org/publication/PubMed/31222110" }, { "database": "PubMed", "id": "31233346", "url": "https://glygen.org/publication/PubMed/31233346" }, { "database": "PubMed", "id": "31707362", "url": "https://glygen.org/publication/PubMed/31707362" }, { "database": "PubMed", "id": "31900153", "url": "https://glygen.org/publication/PubMed/31900153" }, { "database": "PubMed", "id": "33066035", "url": "https://glygen.org/publication/PubMed/33066035" }, { "database": "PubMed", "id": "33495840", "url": "https://glygen.org/publication/PubMed/33495840" }, { "database": "PubMed", "id": "33807180", "url": "https://glygen.org/publication/PubMed/33807180" }, { "database": "PubMed", "id": "35622272", "url": "https://glygen.org/publication/PubMed/35622272" }, { "database": "PubMed", "id": "36090685", "url": "https://glygen.org/publication/PubMed/36090685" }, { "database": "PubMed", "id": "36104259", "url": "https://glygen.org/publication/PubMed/36104259" }, { "database": "PubMed", "id": "23395175", "url": "https://glygen.org/publication/PubMed/23395175" }, { "database": "PubMed", "id": "24742671", "url": "https://glygen.org/publication/PubMed/24742671" }, { "database": "PubMed", "id": "27827363", "url": "https://glygen.org/publication/PubMed/27827363" }, { "database": "PubMed", "id": "22057101", "url": "https://glygen.org/publication/PubMed/22057101" } ], "site_lbl": "Ser9" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q9WV60-1.21.21", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 145 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.85.85", "start_pos": 85, "end_pos": 85, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Identification of zinc-finger BED domain-containing 3 (Zbed3) as a novel Axin-interacting protein that activates Wnt/beta-catenin signaling.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Chen T, Li M, Ding Y, Zhang LS, Xi Y, Pan WJ, Tao DL, Wang JY, Li L", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19141611", "url": "https://glygen.org/publication/PubMed/19141611" } ] } ], "crossref": [ { "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19141611", "url": "https://glygen.org/publication/PubMed/19141611", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "GSFGVVYQAKLCDSGELVAI", "down_seq": "KVLQDKRFKNRELQIMRKLD", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Inhibits interaction with AXIN1 and ZBED3.", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "PubMed", "id": "19141611", "url": "https://glygen.org/publication/PubMed/19141611" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Lithium inhibits stress-induced changes in tau phosphorylation in the mouse hippocampus.", "journal": "Journal of neural transmission (Vienna, Austria : 1996)", "date": "2006", "authors": "Yoshida S, Maeda M, Kaku S, Ikeya H, Yamada K, Nakaike S", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16855914", "url": "https://glygen.org/publication/PubMed/16855914" } ] }, { "title": "BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance.", "journal": "Journal of cellular and molecular medicine", "date": "2010", "authors": "Dobashi T, Tanabe S, Jin H, Mimura N, Yamamoto T, Nishino T, Aoe T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19818092", "url": "https://glygen.org/publication/PubMed/19818092" } ] }, { "title": "Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2010", "authors": "Xu J, Sato S, Okuyama S, Swan RJ, Jacobsen MT, Strunk E, Ikezu T", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "20354135", "url": "https://glygen.org/publication/PubMed/20354135" } ] }, { "title": "Cyanidin-3-glucoside ameliorates ethanol neurotoxicity in the developing brain.", "journal": "Journal of neuroscience research", "date": "2011", "authors": "Ke Z, Liu Y, Wang X, Fan Z, Chen G, Xu M, Bower KA, Frank JA, Ou X, Shi X, Luo J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21671257", "url": "https://glygen.org/publication/PubMed/21671257" } ] }, { "title": "Endoplasmic reticulum stress and glycogen synthase kinase-3beta activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2012", "authors": "McAlpine CS, Bowes AJ, Khan MI, Shi Y, Werstuck GH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "21998135", "url": "https://glygen.org/publication/PubMed/21998135" } ] }, { "title": "Protection by cilostazol against amyloid-beta(1-40)-induced suppression of viability and neurite elongation through activation of CK2alpha in HT22 mouse hippocampal cells.", "journal": "Journal of neuroscience research", "date": "2012", "authors": "Lee HR, Park SY, Kim HY, Shin HK, Lee WS, Rhim BY, Hong KW, Kim CD", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22422579", "url": "https://glygen.org/publication/PubMed/22422579" } ] }, { "title": "Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo.", "journal": "Biochimica et biophysica acta", "date": "2013", "authors": "Lu J, Miao J, Su T, Liu Y, He R", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23628704", "url": "https://glygen.org/publication/PubMed/23628704" } ] }, { "title": "Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo.", "journal": "Oncotarget", "date": "2014-02-15", "authors": "Goc Anna, Al-Husein Belal, Katsanevas Katerina, Steinbach Alison, Lou Uvette, Sabbineni Harika, DeRemer David L, Somanath Payaningal R", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "24519956", "url": "https://glygen.org/publication/PubMed/24519956" } ] }, { "title": "FAK/PYK2 promotes the Wnt/beta-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3beta.", "journal": "eLife", "date": "2015", "authors": "Gao C, Chen G, Kuan SF, Zhang DH, Schlaepfer DD, Hu J", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "26274564", "url": "https://glygen.org/publication/PubMed/26274564" } ] }, { "title": "Neuronal seipin knockout facilitates Abeta-induced neuroinflammation and neurotoxicity via reduction of PPARgamma in hippocampus of mouse.", "journal": "Journal of neuroinflammation", "date": "2016", "authors": "Qian Y, Yin J, Hong J, Li G, Zhang B, Liu G, Wan Q, Chen L", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "27287266", "url": "https://glygen.org/publication/PubMed/27287266" } ] }, { "title": "In vivo regulation of glycogen synthase kinase 3\u03b2 activity in neurons and brains.", "journal": "Scientific reports", "date": "2017-08-17", "authors": "Krishnankutty Ambika, Kimura Taeko, Saito Taro, Aoyagi Kyota, Asada Akiko, Takahashi Shin-Ichiro, Ando Kanae, Ohara-Imaizumi Mica, Ishiguro Koichi, Hisanaga Shin-Ichi", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "28819213", "url": "https://glygen.org/publication/PubMed/28819213" } ] }, { "title": "Inhibition of Glycogen Synthase Kinase 3beta Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia-Mediated Pleural Injury in Mice.", "journal": "The American journal of pathology", "date": "2017", "authors": "Boren J, Shryock G, Fergis A, Jeffers A, Owens S, Qin W, Koenig KB, Tsukasaki Y, Komatsu S, Ikebe M, Idell S, Tucker TA", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29073967", "url": "https://glygen.org/publication/PubMed/29073967" } ] }, { "title": "Seipin deficiency in mice causes loss of dopaminergic neurons via aggregation and phosphorylation of alpha-synuclein and neuroinflammation.", "journal": "Cell death & disease", "date": "2018", "authors": "Wang L, Hong J, Wu Y, Liu G, Yu W, Chen L", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "29670081", "url": "https://glygen.org/publication/PubMed/29670081" } ] }, { "title": "N-(3-methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide promotes bone formation via the canonical Wnt/beta-catenin signaling pathway.", "journal": "Phytotherapy research : PTR", "date": "2019", "authors": "Wang T, Sun CH, Zhong HB, Gong Y, Cui ZK, Xie J, Wang YP, Liang C, Cao HH, Chen XR, Zou ZP, Li SF, Bai XC", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "30768733", "url": "https://glygen.org/publication/PubMed/30768733" } ] } ], "crossref": [ { "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "16855914", "url": "https://glygen.org/publication/PubMed/16855914", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19818092", "url": "https://glygen.org/publication/PubMed/19818092", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20354135", "url": "https://glygen.org/publication/PubMed/20354135", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21671257", "url": "https://glygen.org/publication/PubMed/21671257", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21998135", "url": "https://glygen.org/publication/PubMed/21998135", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22422579", "url": "https://glygen.org/publication/PubMed/22422579", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23628704", "url": "https://glygen.org/publication/PubMed/23628704", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24519956", "url": "https://glygen.org/publication/PubMed/24519956", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26274564", "url": "https://glygen.org/publication/PubMed/26274564", "database": "PubMed", "categories": [ "Other" ] }, { "id": "27287266", "url": "https://glygen.org/publication/PubMed/27287266", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28819213", "url": "https://glygen.org/publication/PubMed/28819213", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29073967", "url": "https://glygen.org/publication/PubMed/29073967", "database": "PubMed", "categories": [ "Other" ] }, { "id": "29670081", "url": "https://glygen.org/publication/PubMed/29670081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "30768733", "url": "https://glygen.org/publication/PubMed/30768733", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LKLCDFGSAKQLVRGEPNVS", "down_seq": "ICSRYYRAPELIFGATDYTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" }, { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "16855914", "url": "https://glygen.org/publication/PubMed/16855914" }, { "database": "PubMed", "id": "19818092", "url": "https://glygen.org/publication/PubMed/19818092" }, { "database": "PubMed", "id": "20354135", "url": "https://glygen.org/publication/PubMed/20354135" }, { "database": "PubMed", "id": "21671257", "url": "https://glygen.org/publication/PubMed/21671257" }, { "database": "PubMed", "id": "21998135", "url": "https://glygen.org/publication/PubMed/21998135" }, { "database": "PubMed", "id": "22422579", "url": "https://glygen.org/publication/PubMed/22422579" }, { "database": "PubMed", "id": "23628704", "url": "https://glygen.org/publication/PubMed/23628704" }, { "database": "PubMed", "id": "24519956", "url": "https://glygen.org/publication/PubMed/24519956" }, { "database": "PubMed", "id": "26274564", "url": "https://glygen.org/publication/PubMed/26274564" }, { "database": "PubMed", "id": "27287266", "url": "https://glygen.org/publication/PubMed/27287266" }, { "database": "PubMed", "id": "28819213", "url": "https://glygen.org/publication/PubMed/28819213" }, { "database": "PubMed", "id": "29073967", "url": "https://glygen.org/publication/PubMed/29073967" }, { "database": "PubMed", "id": "29670081", "url": "https://glygen.org/publication/PubMed/29670081" }, { "database": "PubMed", "id": "30768733", "url": "https://glygen.org/publication/PubMed/30768733" } ], "site_lbl": "Tyr216" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 14 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.21.21", "start_pos": 21, "end_pos": 21, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Anesthesia and post-mortem interval profoundly influence the regulatory serine phosphorylation of glycogen synthase kinase-3 in mouse brain.", "journal": "Journal of neurochemistry", "date": "2005", "authors": "Li X, Friedman AB, Roh MS, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "15659239", "url": "https://glygen.org/publication/PubMed/15659239" } ] }, { "title": "Hepatocyte growth factor suppresses acute renal inflammation by inhibition of endothelial E-selectin.", "journal": "Kidney international", "date": "2006-04", "authors": "Gong R, Rifai A, Dworkin L D", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16501492", "url": "https://glygen.org/publication/PubMed/16501492" } ] }, { "title": "Glycogen synthase kinase-3 regulation of chromatin segregation and cytokinesis in mouse preimplantation embryos.", "journal": "Molecular reproduction and development", "date": "2007", "authors": "Acevedo N, Wang X, Dunn RL, Smith GD", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16941690", "url": "https://glygen.org/publication/PubMed/16941690" } ] }, { "title": "Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3beta) independently of Akt/PKB serine phosphorylation.", "journal": "Journal of cell science", "date": "2006", "authors": "Gartner A, Huang X, Hall A", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "16954147", "url": "https://glygen.org/publication/PubMed/16954147" } ] }, { "title": "Cocaine-induced hyperactivity and sensitization are dependent on GSK3.", "journal": "Neuropharmacology", "date": "2009", "authors": "Miller JS, Tallarida RJ, Unterwald EM", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19328817", "url": "https://glygen.org/publication/PubMed/19328817" } ] }, { "title": "Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease.", "journal": "Current Alzheimer research", "date": "2010", "authors": "Zhuo JM, Portugal GS, Kruger WD, Wang H, Gould TJ, Pratico D", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "19939226", "url": "https://glygen.org/publication/PubMed/19939226" } ] }, { "title": "GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism.", "journal": "PloS one", "date": "2010", "authors": "Mines MA, Yuskaitis CJ, King MK, Beurel E, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "20300527", "url": "https://glygen.org/publication/PubMed/20300527" } ] }, { "title": "HDAC6 regulates LPS-tolerance in astrocytes.", "journal": "PloS one", "date": "2011", "authors": "Beurel E", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22022450", "url": "https://glygen.org/publication/PubMed/22022450" } ] }, { "title": "B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation.", "journal": "PloS one", "date": "2012", "authors": "Wang X, Hao J, Metzger DL, Ao Z, Chen L, Ou D, Verchere CB, Mui A, Warnock GL", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22238573", "url": "https://glygen.org/publication/PubMed/22238573" } ] }, { "title": "Brain region differences in regulation of Akt and GSK3 by chronic stimulant administration in mice.", "journal": "Cellular signalling", "date": "2012", "authors": "Mines MA, Jope RS", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "22434044", "url": "https://glygen.org/publication/PubMed/22434044" } ] }, { "title": "Dual regulation of glycogen synthase kinase 3 (GSK3)alpha/beta by protein kinase C (PKC)alpha and Akt promotes thrombin-mediated integrin alphaIIbbeta3 activation and granule secretion in platelets.", "journal": "The Journal of biological chemistry", "date": "2013", "authors": "Moore SF, van den Bosch MT, Hunter RW, Sakamoto K, Poole AW, Hers I", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "23239877", "url": "https://glygen.org/publication/PubMed/23239877" } ] }, { "title": "GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.", "journal": "eLife", "date": "2014", "authors": "Morgan-Smith M, Wu Y, Zhu X, Pringle J, Snider WD", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25073924", "url": "https://glygen.org/publication/PubMed/25073924" } ] }, { "title": "Innate sensitivity to stress facilitates inflammation, alters metabolism and shortens lifespan in a mouse model of social hierarchy.", "journal": "Aging", "date": "2019-11-09", "authors": "Bairachnaya Maryia, Agranyoni Oryan, Antoch Marina, Michaelevski Izhak, Pinhasov Albert", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31707362", "url": "https://glygen.org/publication/PubMed/31707362" } ] }, { "title": "Dopamine D3 receptor and GSK3beta signaling mediate deficits in novel object recognition memory within dopamine transporter knockdown mice.", "journal": "Journal of biomedical science", "date": "2020", "authors": "Chang PK, Chu J, Tsai YT, Lai YH, Chen JC", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "31900153", "url": "https://glygen.org/publication/PubMed/31900153" } ] } ], "crossref": [ { "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15659239", "url": "https://glygen.org/publication/PubMed/15659239", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16501492", "url": "https://glygen.org/publication/PubMed/16501492", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16941690", "url": "https://glygen.org/publication/PubMed/16941690", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16954147", "url": "https://glygen.org/publication/PubMed/16954147", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19328817", "url": "https://glygen.org/publication/PubMed/19328817", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19939226", "url": "https://glygen.org/publication/PubMed/19939226", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20300527", "url": "https://glygen.org/publication/PubMed/20300527", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22022450", "url": "https://glygen.org/publication/PubMed/22022450", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22238573", "url": "https://glygen.org/publication/PubMed/22238573", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22434044", "url": "https://glygen.org/publication/PubMed/22434044", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23239877", "url": "https://glygen.org/publication/PubMed/23239877", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25073924", "url": "https://glygen.org/publication/PubMed/25073924", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31707362", "url": "https://glygen.org/publication/PubMed/31707362", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31900153", "url": "https://glygen.org/publication/PubMed/31900153", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSGRPRTTSFAESCKPVQQP", "down_seq": "AFGSMKVSRDKDGSKVTTVV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "15659239", "url": "https://glygen.org/publication/PubMed/15659239" }, { "database": "PubMed", "id": "16501492", "url": "https://glygen.org/publication/PubMed/16501492" }, { "database": "PubMed", "id": "16941690", "url": "https://glygen.org/publication/PubMed/16941690" }, { "database": "PubMed", "id": "16954147", "url": "https://glygen.org/publication/PubMed/16954147" }, { "database": "PubMed", "id": "19328817", "url": "https://glygen.org/publication/PubMed/19328817" }, { "database": "PubMed", "id": "19939226", "url": "https://glygen.org/publication/PubMed/19939226" }, { "database": "PubMed", "id": "20300527", "url": "https://glygen.org/publication/PubMed/20300527" }, { "database": "PubMed", "id": "22022450", "url": "https://glygen.org/publication/PubMed/22022450" }, { "database": "PubMed", "id": "22238573", "url": "https://glygen.org/publication/PubMed/22238573" }, { "database": "PubMed", "id": "22434044", "url": "https://glygen.org/publication/PubMed/22434044" }, { "database": "PubMed", "id": "23239877", "url": "https://glygen.org/publication/PubMed/23239877" }, { "database": "PubMed", "id": "25073924", "url": "https://glygen.org/publication/PubMed/25073924" }, { "database": "PubMed", "id": "31707362", "url": "https://glygen.org/publication/PubMed/31707362" }, { "database": "PubMed", "id": "31900153", "url": "https://glygen.org/publication/PubMed/31900153" } ], "site_lbl": "Ser21" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q9WV60-1.9.9", "categories": [ "glycosylation_flag", "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 14 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9WV60-1.356.356", "start_pos": 356, "end_pos": 356, "uniprot_canonical_ac": "Q9WV60-1", "length": 420, "uniprot_id": "GSK3B_MOUSE", "protein_name": "Glycogen synthase kinase-3 beta", "refseq_ac": "NP_062801", "refseq_name": "glycogen synthase kinase-3 beta isoform 1", "gene_name": "Gsk3b", "gene_names_uniprotkb": "Gsk3b", "gene_names_refseq": "7330414F15Rik; 8430431H08Rik; GSK-3beta; GSK-3; GSK3; Gsk3b", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9WV60", "url": "https://www.uniprot.org/uniprotkb/Q9WV60" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation and inactivation of glycogen synthase kinase 3beta (GSK3beta) by dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A).", "journal": "The Journal of biological chemistry", "date": "2015", "authors": "Song WJ, Song EA, Jung MS, Choi SH, Baik HH, Jin BK, Kim JH, Chung SH", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" } ], "reference": [ { "type": "PubMed", "id": "25477508", "url": "https://glygen.org/publication/PubMed/25477508" } ] } ], "crossref": [ { "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "25477508", "url": "https://glygen.org/publication/PubMed/25477508", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AHSFFDELRDPNVKLPNGRD", "down_seq": "PALFNFTTQELSSNPPLATI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9WV60", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9WV60" }, { "database": "PubMed", "id": "25477508", "url": "https://glygen.org/publication/PubMed/25477508" } ], "site_lbl": "Thr356" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "389", "end_pos": "389" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "417", "end_pos": "417" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "85", "end_pos": "85" }, { "start_pos": "9", "end_pos": "9" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "216", "end_pos": "216" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "356", "end_pos": "356" }, { "start_pos": "389", "end_pos": "389" }, { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63085-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney.", "journal": "Development (Cambridge, England)", "date": "2001", "authors": "Fisher CE, Michael L, Barnett MW, Davies JA", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "11684667", "url": "https://glygen.org/publication/PubMed/11684667" } ] }, { "title": "Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Stanciu M, DeFranco DB", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "11726647", "url": "https://glygen.org/publication/PubMed/11726647" } ] }, { "title": "Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2002", "authors": "Noshita N, Sugawara T, Hayashi T, Lewen A, Omar G, Chan PH", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "12223545", "url": "https://glygen.org/publication/PubMed/12223545" } ] }, { "title": "Spatial and temporal patterns of ERK signaling during mouse embryogenesis.", "journal": "Development (Cambridge, England)", "date": "2003", "authors": "Corson LB, Yamanaka Y, Lai KM, Rossant J", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "12925581", "url": "https://glygen.org/publication/PubMed/12925581" } ] }, { "title": "Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.", "journal": "Genes & development", "date": "2004", "authors": "Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jaeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "14744933", "url": "https://glygen.org/publication/PubMed/14744933" } ] }, { "title": "MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Castelli M, Camps M, Gillieron C, Leroy D, Arkinstall S, Rommel C, Nichols A", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "15284227", "url": "https://glygen.org/publication/PubMed/15284227" } ] }, { "title": "MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, Yamamoto T, Saito Y, Nakamura M", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "15314156", "url": "https://glygen.org/publication/PubMed/15314156" } ] }, { "title": "Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2005", "authors": "Moosmang S, Haider N, Klugbauer N, Adelsberger H, Langwieser N, Muller J, Stiess M, Marais E, Schulla V, Lacinova L, Goebbels S, Nave KA, Storm DR, Hofmann F, Kleppisch T", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "16251435", "url": "https://glygen.org/publication/PubMed/16251435" } ] }, { "title": "Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Richards JD, Gold MR, Hourihane SL, DeFranco AL, Matsuuchi L", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "8626447", "url": "https://glygen.org/publication/PubMed/8626447" } ] }, { "title": "Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation.", "journal": "Molecular biology of the cell", "date": "2016", "authors": "Smorodinsky-Atias K, Goshen-Lago T, Goldberg-Carp A, Melamed D, Shir A, Mooshayef N, Beenstock J, Karamansha Y, Darlyuk-Saadon I, Livnah O, Ahn NG, Admon A, Engelberg D", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610" } ] }, { "title": "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Cao L, Yu K, Banh C, Nguyen V, Ritz A, Raphael BJ, Kawakami Y, Kawakami T, Salomon AR", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" } ] }, { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] }, { "title": "Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).", "journal": "The EMBO journal", "date": "1991", "authors": "Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "1849075", "url": "https://glygen.org/publication/PubMed/1849075" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P63085", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63085", "database": "PRO", "categories": [ "Other" ] }, { "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11684667", "url": "https://glygen.org/publication/PubMed/11684667", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11726647", "url": "https://glygen.org/publication/PubMed/11726647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12223545", "url": "https://glygen.org/publication/PubMed/12223545", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12925581", "url": "https://glygen.org/publication/PubMed/12925581", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14744933", "url": "https://glygen.org/publication/PubMed/14744933", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15284227", "url": "https://glygen.org/publication/PubMed/15284227", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15314156", "url": "https://glygen.org/publication/PubMed/15314156", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16251435", "url": "https://glygen.org/publication/PubMed/16251435", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8626447", "url": "https://glygen.org/publication/PubMed/8626447", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "1849075", "url": "https://glygen.org/publication/PubMed/1849075", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ICDFGLARVADPDHDHTGFL", "down_seq": "EYVATRWYRAPEIMLNSKGY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by MAP2K1 and MAP2K2", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "PRO", "id": "P63085", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" }, { "database": "PubMed", "id": "11684667", "url": "https://glygen.org/publication/PubMed/11684667" }, { "database": "PubMed", "id": "11726647", "url": "https://glygen.org/publication/PubMed/11726647" }, { "database": "PubMed", "id": "12223545", "url": "https://glygen.org/publication/PubMed/12223545" }, { "database": "PubMed", "id": "12925581", "url": "https://glygen.org/publication/PubMed/12925581" }, { "database": "PubMed", "id": "14744933", "url": "https://glygen.org/publication/PubMed/14744933" }, { "database": "PubMed", "id": "15284227", "url": "https://glygen.org/publication/PubMed/15284227" }, { "database": "PubMed", "id": "15314156", "url": "https://glygen.org/publication/PubMed/15314156" }, { "database": "PubMed", "id": "16251435", "url": "https://glygen.org/publication/PubMed/16251435" }, { "database": "PubMed", "id": "8626447", "url": "https://glygen.org/publication/PubMed/8626447" }, { "database": "PubMed", "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610" }, { "database": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "PubMed", "id": "1849075", "url": "https://glygen.org/publication/PubMed/1849075" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ], "site_lbl": "Thr183" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P63085-1.185.185", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P63085-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63085-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney.", "journal": "Development (Cambridge, England)", "date": "2001", "authors": "Fisher CE, Michael L, Barnett MW, Davies JA", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "11684667", "url": "https://glygen.org/publication/PubMed/11684667" } ] }, { "title": "Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Stanciu M, DeFranco DB", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "11726647", "url": "https://glygen.org/publication/PubMed/11726647" } ] }, { "title": "Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2002", "authors": "Noshita N, Sugawara T, Hayashi T, Lewen A, Omar G, Chan PH", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "12223545", "url": "https://glygen.org/publication/PubMed/12223545" } ] }, { "title": "Spatial and temporal patterns of ERK signaling during mouse embryogenesis.", "journal": "Development (Cambridge, England)", "date": "2003", "authors": "Corson LB, Yamanaka Y, Lai KM, Rossant J", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "12925581", "url": "https://glygen.org/publication/PubMed/12925581" } ] }, { "title": "Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.", "journal": "Genes & development", "date": "2004", "authors": "Fan M, Rhee J, St-Pierre J, Handschin C, Puigserver P, Lin J, Jaeger S, Erdjument-Bromage H, Tempst P, Spiegelman BM", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "14744933", "url": "https://glygen.org/publication/PubMed/14744933" } ] }, { "title": "MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Castelli M, Camps M, Gillieron C, Leroy D, Arkinstall S, Rommel C, Nichols A", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "15284227", "url": "https://glygen.org/publication/PubMed/15284227" } ] }, { "title": "MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, Yamamoto T, Saito Y, Nakamura M", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "15314156", "url": "https://glygen.org/publication/PubMed/15314156" } ] }, { "title": "Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2005", "authors": "Moosmang S, Haider N, Klugbauer N, Adelsberger H, Langwieser N, Muller J, Stiess M, Marais E, Schulla V, Lacinova L, Goebbels S, Nave KA, Storm DR, Hofmann F, Kleppisch T", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "16251435", "url": "https://glygen.org/publication/PubMed/16251435" } ] }, { "title": "Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Richards JD, Gold MR, Hourihane SL, DeFranco AL, Matsuuchi L", "evidence": [ { "database": "iPTMnet", "id": "P63085-1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085-1" } ], "reference": [ { "type": "PubMed", "id": "8626447", "url": "https://glygen.org/publication/PubMed/8626447" } ] }, { "title": "Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation.", "journal": "Molecular biology of the cell", "date": "2016", "authors": "Smorodinsky-Atias K, Goshen-Lago T, Goldberg-Carp A, Melamed D, Shir A, Mooshayef N, Beenstock J, Karamansha Y, Darlyuk-Saadon I, Livnah O, Ahn NG, Admon A, Engelberg D", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610" } ] }, { "title": "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Cao L, Yu K, Banh C, Nguyen V, Ritz A, Raphael BJ, Kawakami Y, Kawakami T, Salomon AR", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" } ] }, { "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "Journal of proteome research", "date": "2008", "authors": "Ballif BA, Carey GR, Sunyaev SR, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" } ] }, { "title": "Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).", "journal": "The EMBO journal", "date": "1991", "authors": "Payne DM, Rossomando AJ, Martino P, Erickson AK, Her JH, Shabanowitz J, Hunt DF, Weber MJ, Sturgill TW", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "1849075", "url": "https://glygen.org/publication/PubMed/1849075" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P63085", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63085", "database": "PRO", "categories": [ "Other" ] }, { "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "11684667", "url": "https://glygen.org/publication/PubMed/11684667", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11726647", "url": "https://glygen.org/publication/PubMed/11726647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12223545", "url": "https://glygen.org/publication/PubMed/12223545", "database": "PubMed", "categories": [ "Other" ] }, { "id": "12925581", "url": "https://glygen.org/publication/PubMed/12925581", "database": "PubMed", "categories": [ "Other" ] }, { "id": "14744933", "url": "https://glygen.org/publication/PubMed/14744933", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15284227", "url": "https://glygen.org/publication/PubMed/15284227", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15314156", "url": "https://glygen.org/publication/PubMed/15314156", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16251435", "url": "https://glygen.org/publication/PubMed/16251435", "database": "PubMed", "categories": [ "Other" ] }, { "id": "8626447", "url": "https://glygen.org/publication/PubMed/8626447", "database": "PubMed", "categories": [ "Other" ] }, { "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660", "database": "PubMed", "categories": [ "Other" ] }, { "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455", "database": "PubMed", "categories": [ "Other" ] }, { "id": "1849075", "url": "https://glygen.org/publication/PubMed/1849075", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "DFGLARVADPDHDHTGFLTE", "down_seq": "VATRWYRAPEIMLNSKGYTK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by MAP2K1 and MAP2K2", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "PRO", "id": "P63085", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" }, { "database": "PubMed", "id": "11684667", "url": "https://glygen.org/publication/PubMed/11684667" }, { "database": "PubMed", "id": "11726647", "url": "https://glygen.org/publication/PubMed/11726647" }, { "database": "PubMed", "id": "12223545", "url": "https://glygen.org/publication/PubMed/12223545" }, { "database": "PubMed", "id": "12925581", "url": "https://glygen.org/publication/PubMed/12925581" }, { "database": "PubMed", "id": "14744933", "url": "https://glygen.org/publication/PubMed/14744933" }, { "database": "PubMed", "id": "15284227", "url": "https://glygen.org/publication/PubMed/15284227" }, { "database": "PubMed", "id": "15314156", "url": "https://glygen.org/publication/PubMed/15314156" }, { "database": "PubMed", "id": "16251435", "url": "https://glygen.org/publication/PubMed/16251435" }, { "database": "PubMed", "id": "8626447", "url": "https://glygen.org/publication/PubMed/8626447" }, { "database": "PubMed", "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610" }, { "database": "PubMed", "id": "17947660", "url": "https://glygen.org/publication/PubMed/17947660" }, { "database": "PubMed", "id": "18034455", "url": "https://glygen.org/publication/PubMed/18034455" }, { "database": "PubMed", "id": "1849075", "url": "https://glygen.org/publication/PubMed/1849075" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ], "site_lbl": "Tyr185" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P63085-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P63085-1.188.188", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63085-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation.", "journal": "Molecular biology of the cell", "date": "2016", "authors": "Smorodinsky-Atias K, Goshen-Lago T, Goldberg-Carp A, Melamed D, Shir A, Mooshayef N, Beenstock J, Karamansha Y, Darlyuk-Saadon I, Livnah O, Ahn NG, Admon A, Engelberg D", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610" } ] }, { "title": "ERK: A Key Player in the Pathophysiology of Cardiac Hypertrophy.", "journal": "International journal of molecular sciences", "date": "2019", "authors": "Gallo S, Vitacolonna A, Bonzano A, Comoglio P, Crepaldi T", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "31052420", "url": "https://glygen.org/publication/PubMed/31052420" } ] }, { "title": "Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects.", "journal": "Nature communications", "date": "2020-04-07", "authors": "Tomasovic Angela, Brand Theresa, Schanbacher Constanze, Kramer Sofia, H\u00fcmmert Martin W, Godoy Patricio, Schmidt-Heck Wolfgang, Nordbeck Peter, Ludwig Jonas, Homann Susanne, Wiegering Armin, Shaykhutdinov Timur, Kratz Christoph, Kn\u00fcchel Ruth, M\u00fcller-Hermelink Hans-Konrad, Rosenwald Andreas, Frey Norbert, Eichler Jutta, Dobrev Dobromir, El-Armouche Ali, Hengstler Jan G, M\u00fcller Oliver J, Hinrichs Karsten, Cuello Friederike, Zernecke Alma, Lorenz Kristina", "evidence": [ { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" } ], "reference": [ { "type": "PubMed", "id": "32265441", "url": "https://glygen.org/publication/PubMed/32265441" } ] } ], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610", "database": "PubMed", "categories": [ "Other" ] }, { "id": "31052420", "url": "https://glygen.org/publication/PubMed/31052420", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32265441", "url": "https://glygen.org/publication/PubMed/32265441", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LARVADPDHDHTGFLTEYVA", "down_seq": "RWYRAPEIMLNSKGYTKSID", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" }, { "database": "iPTMnet", "id": "P63085", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P63085" }, { "database": "PubMed", "id": "26658610", "url": "https://glygen.org/publication/PubMed/26658610" }, { "database": "PubMed", "id": "31052420", "url": "https://glygen.org/publication/PubMed/31052420" }, { "database": "PubMed", "id": "32265441", "url": "https://glygen.org/publication/PubMed/32265441" } ], "site_lbl": "Thr188" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P63085-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P63085-1.185.185", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P63085-1.244.244", "start_pos": 244, "end_pos": 244, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PIFPGKHYLDQLNHILGILG", "down_seq": "PSQEDLNCIINLKARNYLLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "site_lbl": "Ser244" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P63085-1.246.246", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63085-1.246.246", "start_pos": 246, "end_pos": 246, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FPGKHYLDQLNHILGILGSP", "down_seq": "QEDLNCIINLKARNYLLSLP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "site_lbl": "Ser246" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P63085-1.244.244", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63085-1.27.27", "start_pos": 27, "end_pos": 27, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AGPEMVRGQVFDVGPRYTNL", "down_seq": "YIGEGAYGMVCSAYDNLNKV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by SGK1", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "site_lbl": "Ser27" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P63085-1.282.282", "start_pos": 282, "end_pos": 282, "uniprot_canonical_ac": "P63085-1", "length": 358, "uniprot_id": "MK01_MOUSE", "protein_name": "Mitogen-activated protein kinase 1", "refseq_ac": "NP_001033752", "refseq_name": "mitogen-activated protein kinase 1", "gene_name": "Mapk1", "gene_names_uniprotkb": "Mapk1; Erk2; Mapk; Prkm1", "gene_names_refseq": "9030612K14Rik; ERK; Erk2; MAPK2; Mapk1; PRKM2; Prkm1; p41mapk; p42mapk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LLSLPHKNKVPWNRLFPNAD", "down_seq": "KALDLLDKMLTFNPHKRIEV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P63085", "url": "https://www.uniprot.org/uniprotkb/P63085" } ], "site_lbl": "Ser282" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "183", "end_pos": "183" }, { "start_pos": "185", "end_pos": "185" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "244", "end_pos": "244" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6PGN1-1.229.229", "start_pos": 229, "end_pos": 229, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ELGIYYLPEVEGAFHRGPGL", "down_seq": "LTSGQYTAPVAGFYALAATL", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn229", "evidence": [ { "id": "Q6PGN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "id": "32602701", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Abolishes glycosylation. Abolishes secretion; when associated with Q-281.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.281.281", "start_pos": 281, "end_pos": 281, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PTRPRDRLRLLICIQSLCQH", "down_seq": "ASLETVMGLENSSELFTISV", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn281", "evidence": [ { "id": "Q6PGN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "id": "32602701", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Abolishes glycosylation. Abolishes secretion; when associated with Q-229.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q6PGN1-1.273.273", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q6PGN1-1.278.278", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q6PGN1-1.292.292", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.292.292", "start_pos": 292, "end_pos": 292, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ICIQSLCQHNASLETVMGLE", "down_seq": "SSELFTISVNGVLYLQAGHY", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn292", "evidence": [ { "id": "Q6PGN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "No effect on secretion.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q6PGN1-1.273.273", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q6PGN1-1.278.278", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q6PGN1-1.281.281", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.319.319", "start_pos": 319, "end_pos": 319, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ISVNGVLYLQAGHYTSVFLD", "down_seq": "ASGSSLTVRSGSHFSAILLG", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn319", "evidence": [ { "id": "Q6PGN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Abolishes secretion as a result of protein misfolding, protein is retained in the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q6PGN1-1.321.321", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.142.142", "start_pos": 142, "end_pos": 142, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "KEFQLLLKGAVRQRESHLEH", "down_seq": "TRDLTTPASGSPSRVPAAQE", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Enhances secretion and favors trimer formation.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.194.194", "start_pos": 194, "end_pos": 194, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "LLAATLAQGPRAPRVEAAFH", "down_seq": "RLRRDVQVDRRALHELGIYY", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Enhances secretion and reduces the formation of higher molecular weight oligomers.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.273.273", "start_pos": 273, "end_pos": 273, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "LTEQPRKGPTRPRDRLRLLI", "down_seq": "IQSLCQHNASLETVMGLENS", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes secretion.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q6PGN1-1.278.278", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q6PGN1-1.281.281", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q6PGN1-1.292.292", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.278.278", "start_pos": 278, "end_pos": 278, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "RKGPTRPRDRLRLLICIQSL", "down_seq": "QHNASLETVMGLENSSELFT", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes secretion.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q6PGN1-1.273.273", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q6PGN1-1.281.281", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q6PGN1-1.292.292", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6PGN1-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "Q6PGN1-1", "length": 340, "uniprot_id": "ERFE_MOUSE", "protein_name": "Erythroferrone", "refseq_ac": "NP_775571", "refseq_name": "erythroferrone precursor", "gene_name": "Erfe", "gene_names_uniprotkb": "Erfe; C1qtnf15; Ctrp15; Fam132b", "gene_names_refseq": "4832406C22; Erfe; Fam132b; myonectin", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly.", "journal": "Biochemistry", "date": "2020", "authors": "Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1#ptm_processing" }, { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" } ], "reference": [ { "type": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "crossref": [ { "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VNGVLYLQAGHYTSVFLDNA", "down_seq": "GSSLTVRSGSHFSAILLGL", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "Q", "comment": "No effect on secretion or protein folding.", "evidence": [ { "database": "UniProtKB", "id": "Q6PGN1", "url": "https://www.uniprot.org/uniprotkb/Q6PGN1" }, { "database": "PubMed", "id": "32602701", "url": "https://glygen.org/publication/PubMed/32602701" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "142", "end_pos": "142" }, { "start_pos": "194", "end_pos": "194" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "273", "end_pos": "273" }, { "start_pos": "278", "end_pos": "278" }, { "start_pos": "281", "end_pos": "281" }, { "start_pos": "292", "end_pos": "292" }, { "start_pos": "319", "end_pos": "319" }, { "start_pos": "321", "end_pos": "321" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q6PGN1-1.319.319", "categories": [ "glycosylation_flag", "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BYW9-1.263.263", "start_pos": 263, "end_pos": 263, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization.", "journal": "The Journal of biological chemistry", "date": "2020", "authors": "Alam SMD, Tsukamoto Y, Ogawa M, Senoo Y, Ikeda K, Tashima Y, Takeuchi H, Okajima T", "evidence": [ { "database": "RefSeq", "id": "NP_780522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780522" }, { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "32376684", "url": "https://glygen.org/publication/PubMed/32376684" } ] } ], "crossref": [ { "id": "32376684", "url": "https://glygen.org/publication/PubMed/32376684", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GINMYHHFCDFLNLYLTQHV", "down_seq": "NSFSTDVYIVMWDTSTYGYG", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn263", "evidence": [ { "id": "32376684", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32376684" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8BYW9-1.258.258", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BYW9-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BYW9-1.274.274", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BYW9-1.279.279", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BYW9-1.354.354", "start_pos": 354, "end_pos": 354, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2279", "url": "https://glyconnect.expasy.org/browser/proteins/2279" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "N-Glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization.", "journal": "The Journal of biological chemistry", "date": "2020", "authors": "Alam SMD, Tsukamoto Y, Ogawa M, Senoo Y, Ikeda K, Tashima Y, Takeuchi H, Okajima T", "evidence": [ { "database": "RefSeq", "id": "NP_780522", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780522" }, { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "32376684", "url": "https://glygen.org/publication/PubMed/32376684" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2279", "url": "https://glyconnect.expasy.org/browser/proteins/2279", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32376684", "url": "https://glygen.org/publication/PubMed/32376684", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SGCQNTGLFRAFSQHVLHRL", "down_seq": "ITQEGPKDGKVRVTILARST", "glycosylation": [ { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn354", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2279", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2279" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn354", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2279", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2279" } ] }, { "glytoucan_ac": "G41247ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LNITQEGPKDGK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn354", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true, "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn354", "evidence": [ { "id": "Q8BYW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9#ptm_processing" }, { "id": "32376684", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32376684" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8BYW9-1.337.337", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8BYW9-1.338.338", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BYW9-1.353.353", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BYW9-1.362.362", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BYW9-1.108.108", "start_pos": 108, "end_pos": 108, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388846179", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388846179", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "PEFRFGSPVCSYVDLGWTDT", "down_seq": "ESAQDMFWRQADFGYARERL", "snv": [ { "evidence": [ { "id": "rs3388846179", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388846179" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97119884", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L108", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8BYW9-1.91.91", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8BYW9-1.126.126", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BYW9-1.127.127", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.126.126", "start_pos": 126, "end_pos": 126, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs250972938", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs250972938", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "DTLESAQDMFWRQADFGYAR", "down_seq": "RLGEIRTICQPERASDSSLV", "snv": [ { "evidence": [ { "id": "rs250972938", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs250972938" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97119829", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E126", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8BYW9-1.108.108", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BYW9-1.127.127", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.127.127", "start_pos": 127, "end_pos": 127, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388842138", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388842138", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "TLESAQDMFWRQADFGYARE", "down_seq": "LGEIRTICQPERASDSSLVC", "snv": [ { "evidence": [ { "id": "rs3388842138", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388842138" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97119828", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R127", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BYW9-1.108.108", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BYW9-1.126.126", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.202.202", "start_pos": 202, "end_pos": 202, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388851701", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388851701", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EIGGYCKLDSHALVSEGQRK", "down_seq": "PLQSWFAELQGYTQLNFRPI", "snv": [ { "evidence": [ { "id": "rs3388851701", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388851701" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97111256", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S202", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q8BYW9-1.207.207", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388848181", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388848181", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "CKLDSHALVSEGQRKSPLQS", "down_seq": "FAELQGYTQLNFRPIEDAKC", "snv": [ { "evidence": [ { "id": "rs3388848181", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388848181" } ], "glycoeffect": [], "sequence_org": "W", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97111241", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "W207", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8BYW9-1.202.202", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.21.21", "start_pos": 21, "end_pos": 21, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs37245083", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs37245083", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "MLMLLVFGVLLHEVPLSGQD", "down_seq": "AHSEADDAPGKALYDYSSLR", "snv": [ { "evidence": [ { "id": "rs37245083", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs37245083" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97122371", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K21", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.229.229", "start_pos": 229, "end_pos": 229, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs5527703342", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527703342", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "AELQGYTQLNFRPIEDAKCD", "down_seq": "VVEKPTYFMKLDAGINMYHH", "snv": [ { "evidence": [ { "id": "rs5527703342", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527703342" } ], "glycoeffect": [], "sequence_org": "I", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97108355", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I229", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.258.258", "start_pos": 258, "end_pos": 258, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388837242", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388837242", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "MKLDAGINMYHHFCDFLNLY", "down_seq": "TQHVNNSFSTDVYIVMWDTS", "snv": [ { "evidence": [ { "id": "rs3388837242", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388837242" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97102540", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L258", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q8BYW9-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BYW9-1.263.263", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BYW9-1.274.274", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.260.260", "start_pos": 260, "end_pos": 260, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388824950", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388824950", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "LDAGINMYHHFCDFLNLYLT", "down_seq": "HVNNSFSTDVYIVMWDTSTY", "snv": [ { "evidence": [ { "id": "rs3388824950", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388824950" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97102534", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q260", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8BYW9-1.258.258", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BYW9-1.263.263", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8BYW9-1.274.274", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BYW9-1.279.279", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.274.274", "start_pos": 274, "end_pos": 274, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388841226", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388841226", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "M", "start_aa": "M", "up_seq": "LNLYLTQHVNNSFSTDVYIV", "down_seq": "WDTSTYGYGDLFSDTWKAFT", "snv": [ { "evidence": [ { "id": "rs3388841226", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388841226" } ], "glycoeffect": [], "sequence_org": "M", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97102490", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "M274", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BYW9-1.258.258", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8BYW9-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8BYW9-1.263.263", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BYW9-1.279.279", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs233534008", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs233534008", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TQHVNNSFSTDVYIVMWDTS", "down_seq": "YGYGDLFSDTWKAFTDYDVI", "snv": [ { "evidence": [ { "id": "rs233534008", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs233534008" } ], "glycoeffect": [], "sequence_org": "T", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97097762", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T279", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BYW9-1.260.260", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q8BYW9-1.263.263", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BYW9-1.274.274", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.308.308", "start_pos": 308, "end_pos": 308, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388842080", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388842080", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "DTWKAFTDYDVIHLKTYDSK", "down_seq": "VCFKEAVFSLLPRMRYGLFY", "snv": [ { "evidence": [ { "id": "rs3388842080", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388842080" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97097674", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K308", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q8BYW9-1.324.324", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.324.324", "start_pos": 324, "end_pos": 324, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388853910", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388853910", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "YDSKKVCFKEAVFSLLPRMR", "down_seq": "GLFYNTPLISGCQNTGLFRA", "snv": [ { "evidence": [ { "id": "rs3388853910", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388853910" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97097129", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y324", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BYW9-1.308.308", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BYW9-1.332.332", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8BYW9-1.337.337", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8BYW9-1.338.338", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.332.332", "start_pos": 332, "end_pos": 332, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3397079615", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397079615", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "KEAVFSLLPRMRYGLFYNTP", "down_seq": "ISGCQNTGLFRAFSQHVLHR", "snv": [ { "evidence": [ { "id": "rs3397079615", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397079615" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97097107", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L332", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8BYW9-1.324.324", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BYW9-1.337.337", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BYW9-1.338.338", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.337.337", "start_pos": 337, "end_pos": 337, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388842148", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388842148", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "SLLPRMRYGLFYNTPLISGC", "down_seq": "NTGLFRAFSQHVLHRLNITQ", "snv": [ { "evidence": [ { "id": "rs3388842148", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388842148" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97096996", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q337", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8BYW9-1.324.324", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BYW9-1.332.332", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BYW9-1.338.338", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BYW9-1.353.353", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8BYW9-1.354.354", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.338.338", "start_pos": 338, "end_pos": 338, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388830305", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388830305", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LLPRMRYGLFYNTPLISGCQ", "down_seq": "TGLFRAFSQHVLHRLNITQE", "snv": [ { "evidence": [ { "id": "rs3388830305", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388830305" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97096993", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N338", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8BYW9-1.324.324", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BYW9-1.332.332", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BYW9-1.337.337", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8BYW9-1.353.353", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BYW9-1.354.354", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.353.353", "start_pos": 353, "end_pos": 353, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs52058075", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs52058075", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "ISGCQNTGLFRAFSQHVLHR", "down_seq": "NITQEGPKDGKVRVTILARS", "snv": [ { "evidence": [ { "id": "rs52058075", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs52058075" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97096950", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L353", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BYW9-1.337.337", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8BYW9-1.338.338", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BYW9-1.354.354", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BYW9-1.362.362", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.362.362", "start_pos": 362, "end_pos": 362, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs5527806819", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527806819", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "FRAFSQHVLHRLNITQEGPK", "down_seq": "GKVRVTILARSTEYRKILNQ", "snv": [ { "evidence": [ { "id": "rs5527806819", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5527806819" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97095909", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D362", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8BYW9-1.353.353", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BYW9-1.354.354", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.464.464", "start_pos": 464, "end_pos": 464, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs36830509", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs36830509", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "ELYNCEDERCYLDLARLRGI", "down_seq": "YITWRKPSKVFPQDKGHHPT", "snv": [ { "evidence": [ { "id": "rs36830509", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs36830509" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97089689", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H464", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.507.507", "start_pos": 507, "end_pos": 507, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388846158", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388846158", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "EHPKFTNYSFDVEEFMYLVL", "down_seq": "AAEHVLQHPQWPFKKKHDEL", "snv": [ { "evidence": [ { "id": "rs3388846158", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388846158" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97089084", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q507", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.60.60", "start_pos": 60, "end_pos": 60, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3397089716", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397089716", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "LRLPAEHIPFFLHNNRHVAS", "down_seq": "CREDSHCPYKKHLENLNYCW", "snv": [ { "evidence": [ { "id": "rs3397089716", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397089716" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97122254", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V60", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q8BYW9-1.61.61", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BYW9-1.69.69", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8BYW9-1.79.79", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.61.61", "start_pos": 61, "end_pos": 61, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3397158285", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397158285", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "RLPAEHIPFFLHNNRHVASV", "down_seq": "REDSHCPYKKHLENLNYCWG", "snv": [ { "evidence": [ { "id": "rs3397158285", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397158285" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97122251", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C61", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q8BYW9-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BYW9-1.69.69", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8BYW9-1.79.79", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.69.69", "start_pos": 69, "end_pos": 69, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388850514", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388850514", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs3396672527", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3396672527", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "FFLHNNRHVASVCREDSHCP", "down_seq": "KKHLENLNYCWGYEKSCAPE", "snv": [ { "evidence": [ { "id": "rs3388850514", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388850514" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97122225", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y69", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs3396672527", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3396672527" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97122227", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y69", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8BYW9-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BYW9-1.61.61", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q8BYW9-1.79.79", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8BYW9-1.83.83", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.79.79", "start_pos": 79, "end_pos": 79, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388850538", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388850538", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "SVCREDSHCPYKKHLENLNY", "down_seq": "WGYEKSCAPEFRFGSPVCSY", "snv": [ { "evidence": [ { "id": "rs3388850538", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388850538" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97120977", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C79", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q8BYW9-1.60.60", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q8BYW9-1.61.61", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q8BYW9-1.69.69", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BYW9-1.83.83", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8BYW9-1.91.91", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.83.83", "start_pos": 83, "end_pos": 83, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3397083897", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397083897", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "EDSHCPYKKHLENLNYCWGY", "down_seq": "KSCAPEFRFGSPVCSYVDLG", "snv": [ { "evidence": [ { "id": "rs3397083897", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3397083897" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97120965", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E83", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q8BYW9-1.69.69", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BYW9-1.79.79", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8BYW9-1.91.91", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BYW9-1.91.91", "start_pos": 91, "end_pos": 91, "uniprot_canonical_ac": "Q8BYW9-1", "length": 527, "uniprot_id": "EOGT_MOUSE", "protein_name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "refseq_ac": "NP_780522", "refseq_name": "EGF domain-specific O-linked N-acetylglucosamine transferase precursor", "gene_name": "Eogt", "gene_names_uniprotkb": "Eogt; A130022J15Rik; Aer61; Eogt1", "gene_names_refseq": "A130022J15Rik; Aer61; Eogt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BYW9", "url": "https://www.uniprot.org/uniprotkb/Q8BYW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs36371198", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs36371198", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "KHLENLNYCWGYEKSCAPEF", "down_seq": "FGSPVCSYVDLGWTDTLESA", "snv": [ { "evidence": [ { "id": "rs36371198", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs36371198" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, glycosyltransferase.", "chr_id": "6", "chr_pos": "97120939", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R91", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "263", "end_pos": "263" }, { "start_pos": "354", "end_pos": "354" } ] }, { "type": "snv", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "126", "end_pos": "126" }, { "start_pos": "127", "end_pos": "127" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "21", "end_pos": "21" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "258", "end_pos": "258" }, { "start_pos": "260", "end_pos": "260" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "308", "end_pos": "308" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "332", "end_pos": "332" }, { "start_pos": "337", "end_pos": "337" }, { "start_pos": "338", "end_pos": "338" }, { "start_pos": "353", "end_pos": "353" }, { "start_pos": "362", "end_pos": "362" }, { "start_pos": "464", "end_pos": "464" }, { "start_pos": "507", "end_pos": "507" }, { "start_pos": "60", "end_pos": "60" }, { "start_pos": "61", "end_pos": "61" }, { "start_pos": "69", "end_pos": "69" }, { "start_pos": "79", "end_pos": "79" }, { "start_pos": "83", "end_pos": "83" }, { "start_pos": "91", "end_pos": "91" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8BYW9-1.79.79", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8BYW9-1.83.83", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8BYW9-1.108.108", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O70194-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "O70194-1", "length": 548, "uniprot_id": "EIF3D_MOUSE", "protein_name": "Eukaryotic translation initiation factor 3 subunit D", "refseq_ac": "NP_061219", "refseq_name": "eukaryotic translation initiation factor 3 subunit D", "gene_name": "Eif3d", "gene_names_uniprotkb": "Eif3d; Eif3s7", "gene_names_refseq": "66/67kDa; Eif3d; Eif3s7; eIF3p66", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O70194", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70194" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "O70194", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70194" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "O70194", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70194" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70194", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70194", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "O70194", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O70194" }, { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "161", "end_pos": "161" }, { "start_pos": "528", "end_pos": "528" }, { "start_pos": "529", "end_pos": "529" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70194-1.161.161", "start_pos": 161, "end_pos": 161, "uniprot_canonical_ac": "O70194-1", "length": 548, "uniprot_id": "EIF3D_MOUSE", "protein_name": "Eukaryotic translation initiation factor 3 subunit D", "refseq_ac": "NP_061219", "refseq_name": "eukaryotic translation initiation factor 3 subunit D", "gene_name": "Eif3d", "gene_names_uniprotkb": "Eif3d; Eif3s7", "gene_names_refseq": "66/67kDa; Eif3d; Eif3s7; eIF3p66", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QKQFGVRQKWDQKSQKPRDS", "down_seq": "VEVRSDWEVKEEMDFPQLMK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" } ], "site_lbl": "Ser161" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "161", "end_pos": "161" }, { "start_pos": "528", "end_pos": "528" }, { "start_pos": "529", "end_pos": "529" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O70194-1.528.528", "start_pos": 528, "end_pos": 528, "uniprot_canonical_ac": "O70194-1", "length": 548, "uniprot_id": "EIF3D_MOUSE", "protein_name": "Eukaryotic translation initiation factor 3 subunit D", "refseq_ac": "NP_061219", "refseq_name": "eukaryotic translation initiation factor 3 subunit D", "gene_name": "Eif3d", "gene_names_uniprotkb": "Eif3d; Eif3s7", "gene_names_refseq": "66/67kDa; Eif3d; Eif3s7; eIF3p66", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" }, { "database": "iPTMnet", "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" }, { "database": "iPTMnet", "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ILKDPNKQVIRVYSLPDGTF", "down_seq": "SEEDEEDEEEEEEEEEEEET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194" } ], "site_lbl": "Ser528" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "161", "end_pos": "161" }, { "start_pos": "528", "end_pos": "528" }, { "start_pos": "529", "end_pos": "529" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "O70194-1.529.529", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70194-1.529.529", "start_pos": 529, "end_pos": 529, "uniprot_canonical_ac": "O70194-1", "length": 548, "uniprot_id": "EIF3D_MOUSE", "protein_name": "Eukaryotic translation initiation factor 3 subunit D", "refseq_ac": "NP_061219", "refseq_name": "eukaryotic translation initiation factor 3 subunit D", "gene_name": "Eif3d", "gene_names_uniprotkb": "Eif3d; Eif3s7", "gene_names_refseq": "66/67kDa; Eif3d; Eif3s7; eIF3p66", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" }, { "database": "iPTMnet", "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKDPNKQVIRVYSLPDGTFS", "down_seq": "EEDEEDEEEEEEEEEEEET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70194", "url": "https://www.uniprot.org/uniprotkb/O70194" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "O70194", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70194" } ], "site_lbl": "Ser529" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "161", "end_pos": "161" }, { "start_pos": "528", "end_pos": "528" }, { "start_pos": "529", "end_pos": "529" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "O70194-1.528.528", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q61521-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "Q61521-1", "length": 162, "uniprot_id": "EREG_MOUSE", "protein_name": "Proepiregulin", "refseq_ac": "NP_031976", "refseq_name": "proepiregulin preproprotein", "gene_name": "Ereg", "gene_names_uniprotkb": "Ereg", "gene_names_refseq": "EPR; Ereg", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61521", "url": "https://www.uniprot.org/uniprotkb/Q61521" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q61521", "url": "https://www.uniprot.org/uniprotkb/Q61521", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LQAVISTTVIPSCIPGESED", "down_seq": "CTALVQMEDDPRVAQVQITK", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn40", "evidence": [ { "id": "Q61521", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q61521#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "40", "end_pos": "40" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99K30-1.15.15", "start_pos": 15, "end_pos": 15, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MSQSASMSCCPGAA", "down_seq": "GSLGRSDGVPRMSAKDLFEQ", "glycosylation": [ { "glytoucan_ac": "G05962QB", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "MSQSASMSCCPGAANGSLGR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn15", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q99K30-1.493.493", "start_pos": 493, "end_pos": 493, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "APEDIAPPGSSPHANRGYQP", "down_seq": "PAMTKYVKILYDFTARNANE", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr493", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q99K30-1.489.489", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99K30-1.489.489", "start_pos": 489, "end_pos": 489, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs258379319", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs258379319", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "SESQAPEDIAPPGSSPHANR", "down_seq": "YQPTPAMTKYVKILYDFTAR", "snv": [ { "evidence": [ { "id": "rs258379319", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs258379319" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "G", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NRG->NRS).", "chr_id": "7", "chr_pos": "140940236", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G489", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q99K30-1.493.493", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99K30-1.98.98", "start_pos": 98, "end_pos": 98, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs220262610", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs220262610", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "LVQLSSKEKVWAQEVLLQVN", "down_seq": "KSLRLLDVESQEELENFPLP", "snv": [ { "evidence": [ { "id": "rs220262610", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs220262610" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (DKS->NKS).", "chr_id": "7", "chr_pos": "140934985", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D98", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99K30-1.242.242", "start_pos": 242, "end_pos": 242, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NRVGLPLPVPFSEPGYRRRE", "down_seq": "QDEEPRAVLAQRIEKETQIL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "site_lbl": "Ser242" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99K30-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" }, { "database": "iPTMnet", "id": "Q99K30", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99K30" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" }, { "database": "iPTMnet", "id": "Q99K30", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99K30" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q99K30", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99K30", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LNQRKKGKKKNKKGPAEGVL", "down_seq": "LRARPPSEGEFVDCFQKTKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q99K30", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99K30" } ], "site_lbl": "Thr306" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q99K30-1.573.573", "start_pos": 573, "end_pos": 573, "uniprot_canonical_ac": "Q99K30-1", "length": 729, "uniprot_id": "ES8L2_MOUSE", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "refseq_ac": "NP_573454", "refseq_name": "epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "gene_names_uniprotkb": "Eps8l2; Eps8r2", "gene_names_refseq": "Eps8l2; Eps8r2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RQEDVGAPLEQSGQKYWGPA", "down_seq": "PTHKLPPIFAGNKEELIHHM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99K30", "url": "https://www.uniprot.org/uniprotkb/Q99K30" } ], "site_lbl": "Ser573" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "15", "end_pos": "15" }, { "start_pos": "493", "end_pos": "493" } ] }, { "type": "snv", "site_list": [ { "start_pos": "489", "end_pos": "489" }, { "start_pos": "98", "end_pos": "98" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "242", "end_pos": "242" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "573", "end_pos": "573" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2103.2103", "start_pos": 2103, "end_pos": 2103, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] }, { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.", "journal": "PloS one", "date": "2014", "authors": "Gurel Z, Zaro BW, Pratt MR, Sheibani N", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" } ], "reference": [ { "type": "PubMed", "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80X90", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SPFTVKISGEGRVRESITRT", "down_seq": "RAPAVATVGSICDLNLKIPE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser2103", "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q80X90", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80X90" }, { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "24788674", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24788674" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q80X90-1.2083.2083", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q80X90-1.2113.2113", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80X90-1.2483.2483", "start_pos": 2483, "end_pos": 2483, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SRSPFKAKVTGQRLVSPGSA", "down_seq": "ETSSILVESVTRSSTETCYS", "glycosylation": [ { "glytoucan_ac": "G92050GC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VTGQRLVSPGSANETSSILVESVTR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn2483", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q80X90-1.2465.2465", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q80X90-1.2478.2478", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q80X90-1.2481.2481", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q80X90-1.2492.2492", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q80X90-1.519.519", "start_pos": 519, "end_pos": 519, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ELVKQKGFLDGVYSFEYYPS", "down_seq": "PGKYSVAVTWGGHHIPKSPF", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr519", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Thr519" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "glycosylation_flag", "phosphorylation_flag" ], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q80X90-1.528.528", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.528.528", "start_pos": 528, "end_pos": 528, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DGVYSFEYYPSTPGKYSVAV", "down_seq": "WGGHHIPKSPFEVQVGPEAG", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr528", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q80X90-1.519.519", "categories": [ "glycosylation_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2305.2305", "start_pos": 2305, "end_pos": 2305, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389291709", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389291709", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "DDARCLTVLSLQESGLKVNQ", "down_seq": "ASFAIRLNGAKGKIDAKVHS", "snv": [ { "evidence": [ { "id": "rs3389291709", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389291709" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NQP->NQS).", "chr_id": "14", "chr_pos": "14530702", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P2305", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.1028.1028", "start_pos": 1028, "end_pos": 1028, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PREEGLFAVDVTYDGHPVPG", "down_seq": "PYTVEASLPPDPTKVKAHGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser1028" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.1307.1307", "start_pos": 1307, "end_pos": 1307, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DGTYQVEYTPFEKGFHVVEV", "down_seq": "YDDVPIPNSPFKVAVTEGCQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Thr1307" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q80X90-1.1316.1316", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.1316.1316", "start_pos": 1316, "end_pos": 1316, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFEKGFHVVEVTYDDVPIPN", "down_seq": "PFKVAVTEGCQPSRVHAQGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser1316" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q80X90-1.1307.1307", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.1433.1433", "start_pos": 1433, "end_pos": 1433, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VPSKDVVDPSKVKIAGPGLS", "down_seq": "CVRACIPQSFTVDSSKAGLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser1433" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.1505.1505", "start_pos": 1505, "end_pos": 1505, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PSQEGPYIVSVKYADEEIPR", "down_seq": "PFKVKVLPTYDASKVTASGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser1505" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.1602.1602", "start_pos": 1602, "end_pos": 1602, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PDKTGRYMIGVTYGGDNIPL", "down_seq": "PYRIRATQTGDASKCLATGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser1602" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2083.2083", "start_pos": 2083, "end_pos": 2083, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTVPGVYIVSTKFADEHVPG", "down_seq": "PFTVKISGEGRVRESITRTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2083" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "upstream", "id": "Q80X90-1.2103.2103", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2113.2113", "start_pos": 2113, "end_pos": 2113, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRVRESITRTSRAPAVATVG", "down_seq": "ICDLNLKIPEINSSDMSAHV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2113" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q80X90-1.2103.2103", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DNAREAMQQADDWLGVPQVI", "down_seq": "PEEIIHPDVDEHSVMTYLSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Thr216" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2369.2369", "start_pos": 2369, "end_pos": 2369, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PHENGIHTIDVKFNGSHVVG", "down_seq": "PFKVRVGEPGQAGNPALVSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2369" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2465.2465", "start_pos": 2465, "end_pos": 2465, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MAPGNYLIGVKYGGPNHISR", "down_seq": "PFKAKVTGQRLVSPGSANET", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2465" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q80X90-1.2478.2478", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q80X90-1.2481.2481", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q80X90-1.2483.2483", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2478.2478", "start_pos": 2478, "end_pos": 2478, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GPNHISRSPFKAKVTGQRLV", "down_seq": "PGSANETSSILVESVTRSST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2478" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q80X90-1.2465.2465", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q80X90-1.2481.2481", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q80X90-1.2483.2483", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q80X90-1.2492.2492", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2481.2481", "start_pos": 2481, "end_pos": 2481, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HISRSPFKAKVTGQRLVSPG", "down_seq": "ANETSSILVESVTRSSTETC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2481" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q80X90-1.2465.2465", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q80X90-1.2478.2478", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q80X90-1.2483.2483", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q80X90-1.2492.2492", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.2492.2492", "start_pos": 2492, "end_pos": 2492, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TGQRLVSPGSANETSSILVE", "down_seq": "VTRSSTETCYSAIPKSSSDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser2492" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q80X90-1.2478.2478", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q80X90-1.2481.2481", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q80X90-1.2483.2483", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.730.730", "start_pos": 730, "end_pos": 730, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLKAIKHTIAVVWGGVNIPH", "down_seq": "PYRVNIGQGSHPQKVKVFGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser730" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.886.886", "start_pos": 886, "end_pos": 886, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "THFTVHTKGAGKAPLNVQFS", "down_seq": "PLPGEAVKDLDIIDNYDYSH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser886" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.932.932", "start_pos": 932, "end_pos": 932, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PTQQGNMQVLVTYGGDPIPK", "down_seq": "PFTVGVAAPLDLSKIKINGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser932" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80X90-1.983.983", "start_pos": 983, "end_pos": 983, "uniprot_canonical_ac": "Q80X90-1", "length": 2602, "uniprot_id": "FLNB_MOUSE", "protein_name": "Filamin-B", "refseq_ac": "NP_001074896", "refseq_name": "filamin-B isoform a", "gene_name": "Flnb", "gene_names_uniprotkb": "Flnb", "gene_names_refseq": "Fln-b; Flnb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EFAIDTNGAGGQGKLDVTIL", "down_seq": "PSRKVVPCLVAPVAGRECST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q80X90", "url": "https://www.uniprot.org/uniprotkb/Q80X90" } ], "site_lbl": "Ser983" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "2103", "end_pos": "2103" }, { "start_pos": "2483", "end_pos": "2483" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "528", "end_pos": "528" } ] }, { "type": "snv", "site_list": [ { "start_pos": "2305", "end_pos": "2305" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1028", "end_pos": "1028" }, { "start_pos": "1307", "end_pos": "1307" }, { "start_pos": "1316", "end_pos": "1316" }, { "start_pos": "1433", "end_pos": "1433" }, { "start_pos": "1505", "end_pos": "1505" }, { "start_pos": "1602", "end_pos": "1602" }, { "start_pos": "2083", "end_pos": "2083" }, { "start_pos": "2113", "end_pos": "2113" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "2369", "end_pos": "2369" }, { "start_pos": "2465", "end_pos": "2465" }, { "start_pos": "2478", "end_pos": "2478" }, { "start_pos": "2481", "end_pos": "2481" }, { "start_pos": "2492", "end_pos": "2492" }, { "start_pos": "519", "end_pos": "519" }, { "start_pos": "730", "end_pos": "730" }, { "start_pos": "886", "end_pos": "886" }, { "start_pos": "932", "end_pos": "932" }, { "start_pos": "983", "end_pos": "983" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BLU0-1.202.202", "start_pos": 202, "end_pos": 202, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "5FTT", "url": "https://www.rcsb.org/structure/5FTT", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "5FTT|F|202", "url": "", "database": "", "categories": [ "Other" ] }, { "id": "5FTT|B|202", "url": "", "database": "", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LQELRVDENRIAVISDMAFQ", "down_seq": "LTSLERLIVDGNLLTNKGIA", "glycosylation": [ { "glytoucan_ac": "G20528HD", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "IAVISDMAFQNLTSLER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn202", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=5FTT&bu=0&command=select+.F:202;+center+selection;+zoom+selection" }, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn202", "evidence": [ { "id": "Q8BLU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0#ptm_processing" }, { "id": "5FTT", "database": "PDB", "url": "https://www.rcsb.org/structure/5FTT" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BLU0-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q8BLU0-1.188.188", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "icn3d_view.label", "icn3d_view.url" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "icn3d_view.label", "icn3d_view.url" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "icn3d_view.label", "icn3d_view.url" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BLU0-1.401.401", "start_pos": 401, "end_pos": 401, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "TQSPTLSVPSPSRGSVPPAP", "down_seq": "PSKLPTIPDWDGRERVTPPI", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8BLU0-1.170.170", "start_pos": 170, "end_pos": 170, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.", "journal": "Neuron", "date": "2014", "authors": "Seiradake E, del Toro D, Nagel D, Cop F, Hartl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "reference": [ { "type": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "crossref": [ { "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "VEDGAFREAISLKLLFLSKN", "down_seq": "LSSVPVGLPVDLQELRVDEN", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "E", "comment": "Abolishes interaction with UNC5D.", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" }, { "database": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] }, { "sequence_org": "H", "sequence_mut": "N", "comment": "Abolishes interaction with UNC5D.", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" }, { "database": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q8BLU0-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8BLU0-1.188.188", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BLU0-1.186.186", "start_pos": 186, "end_pos": 186, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.", "journal": "Neuron", "date": "2014", "authors": "Seiradake E, del Toro D, Nagel D, Cop F, Hartl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "reference": [ { "type": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "crossref": [ { "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "LSKNHLSSVPVGLPVDLQEL", "down_seq": "VDENRIAVISDMAFQNLTSL", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "N", "comment": "Abolishes homooligomerization and FLRT2-mediated cell-cell adhesion; when associated with T-188.", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" }, { "database": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BLU0-1.170.170", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BLU0-1.188.188", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BLU0-1.202.202", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BLU0-1.188.188", "start_pos": 188, "end_pos": 188, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.", "journal": "Neuron", "date": "2014", "authors": "Seiradake E, del Toro D, Nagel D, Cop F, Hartl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "reference": [ { "type": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "crossref": [ { "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "KNHLSSVPVGLPVDLQELRV", "down_seq": "ENRIAVISDMAFQNLTSLER", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "T", "comment": "Abolishes homooligomerization and FLRT2-mediated cell-cell adhesion; when associated with N-186.", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" }, { "database": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8BLU0-1.170.170", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BLU0-1.186.186", "categories": [ "mutagenesis_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q8BLU0-1.202.202", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BLU0-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.", "journal": "Neuron", "date": "2014", "authors": "Seiradake E, del Toro D, Nagel D, Cop F, Hartl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "reference": [ { "type": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "crossref": [ { "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "HLTKLKEFSIVRNSLSHPPP", "down_seq": "LPGTHLIRLYLQDNQINHIP", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "No effect on interaction with UNC5D; when associated with T-250.", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" }, { "database": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q8BLU0-1.250.250", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BLU0-1.250.250", "start_pos": 250, "end_pos": 250, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.", "journal": "Neuron", "date": "2014", "authors": "Seiradake E, del Toro D, Nagel D, Cop F, Hartl R, Ruff T, Seyit-Bremer G, Harlos K, Border EC, Acker-Palmer A, Jones EY, Klein R", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "reference": [ { "type": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "crossref": [ { "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "TKLKEFSIVRNSLSHPPPDL", "down_seq": "GTHLIRLYLQDNQINHIPLT", "mutagenesis": [ { "sequence_org": "P", "sequence_mut": "T", "comment": "No effect on interaction with UNC5D; when associated with N-248.", "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" }, { "database": "PubMed", "id": "25374360", "url": "https://glygen.org/publication/PubMed/25374360" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q8BLU0-1.248.248", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BLU0-1.79.79", "start_pos": 79, "end_pos": 79, "uniprot_canonical_ac": "Q8BLU0-1", "length": 660, "uniprot_id": "FLRT2_MOUSE", "protein_name": "Leucine-rich repeat transmembrane protein FLRT2", "refseq_ac": "NP_958926", "refseq_name": "leucine-rich repeat transmembrane protein FLRT2 isoform 1 precursor", "gene_name": "Flrt2", "gene_names_uniprotkb": "Flrt2; Kiaa0405", "gene_names_refseq": "Flrt2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BLU0", "url": "https://www.uniprot.org/uniprotkb/Q8BLU0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389239464", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389239464", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "LGIPEGVTVLYLHNNQINNA", "down_seq": "FPAELHNVQSVHTVYLYGNQ", "snv": [ { "evidence": [ { "id": "rs3389239464", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389239464" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "G", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NAG->NAC).", "chr_id": "12", "chr_pos": "95745898", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G79", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "202", "end_pos": "202" }, { "start_pos": "401", "end_pos": "401" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "170", "end_pos": "170" }, { "start_pos": "186", "end_pos": "186" }, { "start_pos": "188", "end_pos": "188" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" } ] }, { "type": "snv", "site_list": [ { "start_pos": "79", "end_pos": "79" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8R1M2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8R1M2-1", "length": 129, "uniprot_id": "H2AJ_MOUSE", "protein_name": "Histone H2A.J", "refseq_ac": "NP_808356", "refseq_name": "histone H2A.J", "gene_name": "H2aj", "gene_names_uniprotkb": "H2aj", "gene_names_refseq": "E130307C13; H2afj; H2aj", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R1M2", "url": "https://www.uniprot.org/uniprotkb/Q8R1M2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8R1M2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R1M2" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8R1M2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R1M2" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8R1M2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R1M2" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8R1M2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R1M2" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8R1M2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R1M2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q8R1M2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8R1M2" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "121", "end_pos": "121" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8R1M2-1.121.121", "start_pos": 121, "end_pos": 121, "uniprot_canonical_ac": "Q8R1M2-1", "length": 129, "uniprot_id": "H2AJ_MOUSE", "protein_name": "Histone H2A.J", "refseq_ac": "NP_808356", "refseq_name": "histone H2A.J", "gene_name": "H2aj", "gene_names_uniprotkb": "H2aj", "gene_names_refseq": "E130307C13; H2afj; H2aj", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R1M2", "url": "https://www.uniprot.org/uniprotkb/Q8R1M2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8R1M2", "url": "https://www.uniprot.org/uniprotkb/Q8R1M2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VTIAQGGVLPNIQAVLLPKK", "down_seq": "ESQKVKSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by DCAF1", "evidence": [ { "database": "UniProtKB", "id": "Q8R1M2", "url": "https://www.uniprot.org/uniprotkb/Q8R1M2" } ], "site_lbl": "Thr121" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "121", "end_pos": "121" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NVF4-1.892.892", "start_pos": 892, "end_pos": 892, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VVYVVGKAGRQHWQHVYTAV", "down_seq": "RGRSRVYIIAQESELRSATR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr892", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NVF4-1.1029.1038", "start_pos": 1029, "end_pos": 1038, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "HELB Is a Feedback Inhibitor of DNA End Resection.", "journal": "Molecular cell", "date": "2016", "authors": "Tkac J, Xu G, Adhikary H, Young JTF, Gallo D, Escribano-Diaz C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, Gingras AC, Rottenberg S, Masson JY, Durocher D", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "RefSeq", "id": "NP_536694", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_536694" } ], "reference": [ { "type": "PubMed", "id": "26774285", "url": "https://glygen.org/publication/PubMed/26774285" } ] } ], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26774285", "url": "https://glygen.org/publication/PubMed/26774285", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "VSSVFQNMRL", "start_aa": "V", "up_seq": "FPFDEESPSKFRMVEAPSPQ", "down_seq": "NTLTPRQLFKPTDNQDTGTA", "mutagenesis": [ { "sequence_org": "VSSVFQNMRL", "sequence_mut": "ASSVAQNARA", "comment": "Accumulation in the nucleus due to defects in nuclear export.", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "PubMed", "id": "26774285", "url": "https://glygen.org/publication/PubMed/26774285" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q6NVF4-1.1015.1015", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q6NVF4-1.1026.1026", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NVF4-1.462.462", "start_pos": 462, "end_pos": 462, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "HELB Is a Feedback Inhibitor of DNA End Resection.", "journal": "Molecular cell", "date": "2016", "authors": "Tkac J, Xu G, Adhikary H, Young JTF, Gallo D, Escribano-Diaz C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, Gingras AC, Rottenberg S, Masson JY, Durocher D", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "RefSeq", "id": "NP_536694", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_536694" } ], "reference": [ { "type": "PubMed", "id": "26774285", "url": "https://glygen.org/publication/PubMed/26774285" } ] } ], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "26774285", "url": "https://glygen.org/publication/PubMed/26774285", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "ALETICANAVTVLSGKGGCG", "down_seq": "TTIVSRLFKHMEHLEETEVQ", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "No ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "PubMed", "id": "26774285", "url": "https://glygen.org/publication/PubMed/26774285" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NVF4-1.1015.1015", "start_pos": 1015, "end_pos": 1015, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ESAQLRGSKRIGDGFPFDEE", "down_seq": "PSKFRMVEAPSPQVSSVFQN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "site_lbl": "Ser1015" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "Q6NVF4-1.1026.1026", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q6NVF4-1.1029.1038", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NVF4-1.1026.1026", "start_pos": 1026, "end_pos": 1026, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GDGFPFDEESPSKFRMVEAP", "down_seq": "PQVSSVFQNMRLNTLTPRQL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "site_lbl": "Ser1026" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q6NVF4-1.1015.1015", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q6NVF4-1.1029.1038", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6NVF4-1.942.942", "start_pos": 942, "end_pos": 942, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKHFLQKKLSGSCAPSTGFA", "down_seq": "QPSSPRVGGRPDTQPPASHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "site_lbl": "Ser942" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q6NVF4-1.946.946", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NVF4-1.946.946", "start_pos": 946, "end_pos": 946, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQKKLSGSCAPSTGFASQPS", "down_seq": "PRVGGRPDTQPPASHLCRTP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "site_lbl": "Ser946" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q6NVF4-1.942.942", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6NVF4-1.992.992", "start_pos": 992, "end_pos": 992, "uniprot_canonical_ac": "Q6NVF4-1", "length": 1074, "uniprot_id": "HELB_MOUSE", "protein_name": "DNA helicase B", "refseq_ac": "NP_536694", "refseq_name": "DNA helicase B", "gene_name": "Helb", "gene_names_uniprotkb": "Helb", "gene_names_refseq": "D10Ertd664e; Helb", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ADSARGDERWLSASVNDDVD", "down_seq": "DEESAQLRGSKRIGDGFPFD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q6NVF4", "url": "https://www.uniprot.org/uniprotkb/Q6NVF4" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6NVF4", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6NVF4" } ], "site_lbl": "Thr992" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "892", "end_pos": "892" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1029", "end_pos": "1038" }, { "start_pos": "462", "end_pos": "462" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1015", "end_pos": "1015" }, { "start_pos": "1026", "end_pos": "1026" }, { "start_pos": "942", "end_pos": "942" }, { "start_pos": "946", "end_pos": "946" }, { "start_pos": "992", "end_pos": "992" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P84244-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P84244", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P84244" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P84244", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P84244" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P84244", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P84244", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "P84244", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P84244" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P84244-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P84244-1.6.6", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P84244-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P84244-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P84244-1.6.6", "start_pos": 6, "end_pos": 6, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3.", "journal": "Nature", "date": "2019", "authors": "Farrelly LA, Thompson RE, Zhao S, Lepack AE, Lyu Y, Bhanu NV, Zhang B, Loh YE, Ramakrishnan A, Vadodaria KC, Heard KJ, Erikson G, Nakadai T, Bastle RM, Lukasak BJ, Zebroski H 3rd, Alenina N, Bader M, Berton O, Roeder RG, Molina H, Gage FH, Shen L, Garcia BA, Li H, Muir TW, Maze I", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "reference": [ { "type": "PubMed", "id": "30867594", "url": "https://glygen.org/publication/PubMed/30867594" } ] } ], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30867594", "url": "https://glygen.org/publication/PubMed/30867594", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "MARTK", "down_seq": "TARKSTGGKAPRKQLATKAA", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "Abolished serotonylation by TGM2. Reduced neurite length.", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "PubMed", "id": "30867594", "url": "https://glygen.org/publication/PubMed/30867594" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P84244-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P84244-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P84244-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P84244-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P84244-1.108.108", "start_pos": 108, "end_pos": 108, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AAIGALQEASEAYLVGLFED", "down_seq": "NLCAIHAKRVTIMPKDIQLA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Thr108" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.11.11", "start_pos": 11, "end_pos": 11, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.", "journal": "The Journal of biological chemistry", "date": "1999", "authors": "Goto H, Tomono Y, Ajiro K, Kosako H, Fujita M, Sakurai M, Okawa K, Iwamatsu A, Okigaki T, Takahashi T, Inagaki M", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "10464286", "url": "https://glygen.org/publication/PubMed/10464286" } ] }, { "title": "Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "2002", "authors": "Goto H, Yasui Y, Nigg EA, Inagaki M", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "11856369", "url": "https://glygen.org/publication/PubMed/11856369" } ] }, { "title": "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.", "journal": "Genes & development", "date": "2005", "authors": "Dai J, Sultan S, Taylor SS, Higgins JM", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15681610", "url": "https://glygen.org/publication/PubMed/15681610" } ] }, { "title": "Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28.", "journal": "Oncogene", "date": "2005", "authors": "Dunn KL, Davie JR", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15735677", "url": "https://glygen.org/publication/PubMed/15735677" } ] }, { "title": "MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.", "journal": "Journal of cell science", "date": "2005", "authors": "Dyson MH, Thomson S, Inagaki M, Goto H, Arthur SJ, Nightingale K, Iborra FJ, Mahadevan LC", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15870105", "url": "https://glygen.org/publication/PubMed/15870105" } ] } ], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "10464286", "url": "https://glygen.org/publication/PubMed/10464286", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11856369", "url": "https://glygen.org/publication/PubMed/11856369", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15681610", "url": "https://glygen.org/publication/PubMed/15681610", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15735677", "url": "https://glygen.org/publication/PubMed/15735677", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15870105", "url": "https://glygen.org/publication/PubMed/15870105", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MARTKQTARK", "down_seq": "TGGKAPRKQLATKAARKSAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" }, { "database": "PubMed", "id": "10464286", "url": "https://glygen.org/publication/PubMed/10464286" }, { "database": "PubMed", "id": "11856369", "url": "https://glygen.org/publication/PubMed/11856369" }, { "database": "PubMed", "id": "15681610", "url": "https://glygen.org/publication/PubMed/15681610" }, { "database": "PubMed", "id": "15735677", "url": "https://glygen.org/publication/PubMed/15735677" }, { "database": "PubMed", "id": "15870105", "url": "https://glygen.org/publication/PubMed/15870105" } ], "site_lbl": "Ser11" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P84244-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P84244-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P84244-1.6.6", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P84244-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P84244-1.29.29", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P84244-1.12.12", "start_pos": 12, "end_pos": 12, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MARTKQTARKS", "down_seq": "GGKAPRKQLATKAARKSAPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PKC", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Thr12" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P84244-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P84244-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P84244-1.6.6", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P84244-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P84244-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P84244-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P84244-1.32.32", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.29.29", "start_pos": 29, "end_pos": 29, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.", "journal": "The Journal of biological chemistry", "date": "1999", "authors": "Goto H, Tomono Y, Ajiro K, Kosako H, Fujita M, Sakurai M, Okawa K, Iwamatsu A, Okigaki T, Takahashi T, Inagaki M", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "10464286", "url": "https://glygen.org/publication/PubMed/10464286" } ] }, { "title": "Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Zhong S, Jansen C, She QB, Goto H, Inagaki M, Bode AM, Ma WY, Dong Z", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "11441012", "url": "https://glygen.org/publication/PubMed/11441012" } ] }, { "title": "Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "2002", "authors": "Goto H, Yasui Y, Nigg EA, Inagaki M", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "11856369", "url": "https://glygen.org/publication/PubMed/11856369" } ] }, { "title": "Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Choi HS, Choi BY, Cho YY, Zhu F, Bode AM, Dong Z", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15684425", "url": "https://glygen.org/publication/PubMed/15684425" } ] }, { "title": "Stimulation of the Ras-MAPK pathway leads to independent phosphorylation of histone H3 on serine 10 and 28.", "journal": "Oncogene", "date": "2005", "authors": "Dunn KL, Davie JR", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15735677", "url": "https://glygen.org/publication/PubMed/15735677" } ] }, { "title": "MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.", "journal": "Journal of cell science", "date": "2005", "authors": "Dyson MH, Thomson S, Inagaki M, Goto H, Arthur SJ, Nightingale K, Iborra FJ, Mahadevan LC", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15870105", "url": "https://glygen.org/publication/PubMed/15870105" } ] } ], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "10464286", "url": "https://glygen.org/publication/PubMed/10464286", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11441012", "url": "https://glygen.org/publication/PubMed/11441012", "database": "PubMed", "categories": [ "Other" ] }, { "id": "11856369", "url": "https://glygen.org/publication/PubMed/11856369", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15684425", "url": "https://glygen.org/publication/PubMed/15684425", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15735677", "url": "https://glygen.org/publication/PubMed/15735677", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15870105", "url": "https://glygen.org/publication/PubMed/15870105", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKSTGGKAPRKQLATKAARK", "down_seq": "APSTGGVKKPHRYRPGTVAL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" }, { "database": "PubMed", "id": "10464286", "url": "https://glygen.org/publication/PubMed/10464286" }, { "database": "PubMed", "id": "11441012", "url": "https://glygen.org/publication/PubMed/11441012" }, { "database": "PubMed", "id": "11856369", "url": "https://glygen.org/publication/PubMed/11856369" }, { "database": "PubMed", "id": "15684425", "url": "https://glygen.org/publication/PubMed/15684425" }, { "database": "PubMed", "id": "15735677", "url": "https://glygen.org/publication/PubMed/15735677" }, { "database": "PubMed", "id": "15870105", "url": "https://glygen.org/publication/PubMed/15870105" } ], "site_lbl": "Ser29" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P84244-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "downstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P84244-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P84244-1.42.42", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P84244-1.32.32", "start_pos": 32, "end_pos": 32, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TGGKAPRKQLATKAARKSAP", "down_seq": "TGGVKKPHRYRPGTVALREI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Ser32" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P84244-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P84244-1.42.42", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.42.42", "start_pos": 42, "end_pos": 42, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "ATKAARKSAPSTGGVKKPHR", "down_seq": "RPGTVALREIRRYQKSTELL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Tyr42" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P84244-1.29.29", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P84244-1.32.32", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P84244-1.58.58", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.4.4", "start_pos": 4, "end_pos": 4, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment.", "journal": "Genes & development", "date": "2005", "authors": "Dai J, Sultan S, Taylor SS, Higgins JM", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" } ], "reference": [ { "type": "PubMed", "id": "15681610", "url": "https://glygen.org/publication/PubMed/15681610" } ] } ], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15681610", "url": "https://glygen.org/publication/PubMed/15681610", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MAR", "down_seq": "KQTARKSTGGKAPRKQLATK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by HASPIN and VRK1", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" }, { "database": "iPTMnet", "id": "P84244", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P84244" }, { "database": "PubMed", "id": "15681610", "url": "https://glygen.org/publication/PubMed/15681610" } ], "site_lbl": "Thr4" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P84244-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P84244-1.6.6", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P84244-1.7.7", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P84244-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P84244-1.58.58", "start_pos": 58, "end_pos": 58, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KPHRYRPGTVALREIRRYQK", "down_seq": "TELLIRKLPFQRLVREIAQD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Ser58" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P84244-1.42.42", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.7.7", "start_pos": 7, "end_pos": 7, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MARTKQ", "down_seq": "ARKSTGGKAPRKQLATKAAR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PKC", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Thr7" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P84244-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P84244-1.4.4", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P84244-1.6.6", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P84244-1.11.11", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P84244-1.12.12", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.81.81", "start_pos": 81, "end_pos": 81, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LLIRKLPFQRLVREIAQDFK", "down_seq": "DLRFQSAAIGALQEASEAYL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Thr81" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P84244-1.87.87", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P84244-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "P84244-1", "length": 136, "uniprot_id": "H33_MOUSE", "protein_name": "Histone H3.3", "refseq_ac": "NP_032236", "refseq_name": "histone H3.3", "gene_name": "H3-3a; H3-3b; H3f3a", "gene_names_uniprotkb": "H3-3a; H3-3b; H3f3a; H3.3a; H3.3b; H3f3a; H3f3b", "gene_names_refseq": "EyeLinc14; H3-3a; H3-3b; H3.3A; H3f3a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFQRLVREIAQDFKTDLRFQ", "down_seq": "AAIGALQEASEAYLVGLFED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P84244", "url": "https://www.uniprot.org/uniprotkb/P84244" } ], "site_lbl": "Ser87" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "6", "end_pos": "6" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "108", "end_pos": "108" }, { "start_pos": "11", "end_pos": "11" }, { "start_pos": "12", "end_pos": "12" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "32", "end_pos": "32" }, { "start_pos": "42", "end_pos": "42" }, { "start_pos": "4", "end_pos": "4" }, { "start_pos": "58", "end_pos": "58" }, { "start_pos": "7", "end_pos": "7" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P84244-1.81.81", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P36552-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P36552-1", "length": 443, "uniprot_id": "HEM6_MOUSE", "protein_name": "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "refseq_ac": "NP_031783", "refseq_name": "oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor", "gene_name": "Cpox", "gene_names_uniprotkb": "Cpox; Cpo", "gene_names_refseq": "CPX; Cpox; Cpo; HCP; M100835; Rgsc835; cac; nct", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P36552", "url": "https://www.uniprot.org/uniprotkb/P36552" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "CBS homogenization mutation strategy narrows the glycan binding profile of a GlcNAc-specific lectin AANL.", "journal": "Glycobiology", "date": "2020", "authors": "Su Y, Ye X, Xu B, Li Y, Yang Q, Yu W, Song J, Guo C, Wang X, Hart GW, Sun H", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "P36552", "url": "https://oglcnac.org/atlas/detail/P36552" } ], "reference": [ { "type": "PubMed", "id": "31616917", "url": "https://glygen.org/publication/PubMed/31616917" } ] } ], "crossref": [ { "id": "31616917", "url": "https://glygen.org/publication/PubMed/31616917", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P36552", "url": "https://oglcnac.org/atlas/detail/P36552", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGITCVLQDGRVFEKAGVSI", "down_seq": "VVHGNLSEEAANQMRGRGKT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser197", "evidence": [ { "id": "31616917", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/31616917" }, { "id": "P36552", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/P36552" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "197", "end_pos": "197" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P36552-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P36552-1", "length": 443, "uniprot_id": "HEM6_MOUSE", "protein_name": "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "refseq_ac": "NP_031783", "refseq_name": "oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor", "gene_name": "Cpox", "gene_names_uniprotkb": "Cpox; Cpo", "gene_names_refseq": "CPX; Cpox; Cpo; HCP; M100835; Rgsc835; cac; nct", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P36552", "url": "https://www.uniprot.org/uniprotkb/P36552" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P36552", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P36552" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P36552", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P36552", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P36552", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P36552" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "197", "end_pos": "197" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P36552-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "P36552-1", "length": 443, "uniprot_id": "HEM6_MOUSE", "protein_name": "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "refseq_ac": "NP_031783", "refseq_name": "oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor", "gene_name": "Cpox", "gene_names_uniprotkb": "Cpox; Cpo", "gene_names_refseq": "CPX; Cpox; Cpo; HCP; M100835; Rgsc835; cac; nct", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P36552", "url": "https://www.uniprot.org/uniprotkb/P36552" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P36552", "url": "https://www.uniprot.org/uniprotkb/P36552", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AFGHVQRAEMVPKSSGARSP", "down_seq": "PGRREEDGDELARRCSTFMS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P36552", "url": "https://www.uniprot.org/uniprotkb/P36552" } ], "site_lbl": "Ser101" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "197", "end_pos": "197" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "101", "end_pos": "101" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3UMU9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UMU9", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "Q3UMU9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3UMU9" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.523.524", "start_pos": 523, "end_pos": 524, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "HRP2-DPF3a-BAF complex coordinates histone modification and chromatin remodeling to regulate myogenic gene transcription.", "journal": "Nucleic acids research", "date": "2020", "authors": "Zhu X, Lan B, Yi X, He C, Dang L, Zhou X, Lu Y, Sun Y, Liu Z, Bai X, Zhang K, Li B, Li MJ, Chen Y, Zhang L", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "RefSeq", "id": "NP_001291713", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001291713" } ], "reference": [ { "type": "PubMed", "id": "32459350", "url": "https://glygen.org/publication/PubMed/32459350" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "32459350", "url": "https://glygen.org/publication/PubMed/32459350", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "RR", "start_aa": "R", "up_seq": "QVTSQILQKNTDVVATLKKI", "down_seq": "YKANKDVMAKAAEVYTRLKS", "mutagenesis": [ { "sequence_org": "RR", "sequence_mut": "AA", "comment": "Loss of interaction with SMARCA4.", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "32459350", "url": "https://glygen.org/publication/PubMed/32459350" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.114.114", "start_pos": 114, "end_pos": 114, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "APPPVSSSDSEAPEADLGCG", "down_seq": "DVDKDKESRRVMTVTAVTTT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser114" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.137.137", "start_pos": 137, "end_pos": 137, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKDKESRRVMTVTAVTTTAT", "down_seq": "DRMESDSDSDKSSDHSGLKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser137" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.165.165", "start_pos": 165, "end_pos": 165, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSDKSSDHSGLKRKTPVLKV", "down_seq": "VSKRARRASSDLDQASVSPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser165" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.229.229", "start_pos": 229, "end_pos": 229, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TAARPPRRGPLGGRKKKKVP", "down_seq": "ASDSDSKADSDGAKEEPVVT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser229" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q3UMU9-1.231.231", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q3UMU9-1.233.233", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q3UMU9-1.239.239", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.231.231", "start_pos": 231, "end_pos": 231, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ARPPRRGPLGGRKKKKVPSA", "down_seq": "DSDSKADSDGAKEEPVVTAQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser231" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q3UMU9-1.229.229", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3UMU9-1.233.233", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q3UMU9-1.239.239", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.233.233", "start_pos": 233, "end_pos": 233, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPRRGPLGGRKKKKVPSASD", "down_seq": "DSKADSDGAKEEPVVTAQPS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser233" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q3UMU9-1.229.229", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q3UMU9-1.231.231", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q3UMU9-1.239.239", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.239.239", "start_pos": 239, "end_pos": 239, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LGGRKKKKVPSASDSDSKAD", "down_seq": "DGAKEEPVVTAQPSPSSSSS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser239" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q3UMU9-1.229.229", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q3UMU9-1.231.231", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q3UMU9-1.233.233", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.268.268", "start_pos": 268, "end_pos": 268, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VTAQPSPSSSSSSSSSSSSD", "down_seq": "DVSVKKPPRGRKPAEKPPPK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser268" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.307.307", "start_pos": 307, "end_pos": 307, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKPRGRRPKPERPPSTSSSD", "down_seq": "DSDSGEVDRISEWKRRDEER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser307" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.366.366", "start_pos": 366, "end_pos": 366, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.", "journal": "Journal of proteome research", "date": "2007", "authors": "Smith JC, Duchesne MA, Tozzi P, Ethier M, Figeys D", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" } ] }, { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165", "database": "PubMed", "categories": [ "Other" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LREQEREEKERRKERAERGG", "down_seq": "SGEELEDEEPVKKRSRKARG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser366" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q3UMU9-1.367.367", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.367.367", "start_pos": 367, "end_pos": 367, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphoproteomic analysis of the developing mouse brain.", "journal": "Molecular & cellular proteomics : MCP", "date": "2004", "authors": "Ballif BA, Villen J, Beausoleil SA, Schwartz D, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" } ] }, { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.", "journal": "Journal of proteome research", "date": "2007", "authors": "Smith JC, Duchesne MA, Tozzi P, Ethier M, Figeys D", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "REQEREEKERRKERAERGGS", "down_seq": "GEELEDEEPVKKRSRKARGR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "15345747", "url": "https://glygen.org/publication/PubMed/15345747" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "17622165", "url": "https://glygen.org/publication/PubMed/17622165" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser367" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q3UMU9-1.366.366", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.391.391", "start_pos": 391, "end_pos": 391, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LEDEEPVKKRSRKARGRGTP", "down_seq": "SSDSEPEGELGKEGKKLAKK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser391" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q3UMU9-1.392.392", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3UMU9-1.393.393", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q3UMU9-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.392.392", "start_pos": 392, "end_pos": 392, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDEEPVKKRSRKARGRGTPS", "down_seq": "SDSEPEGELGKEGKKLAKKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser392" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q3UMU9-1.391.391", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q3UMU9-1.393.393", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q3UMU9-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.393.393", "start_pos": 393, "end_pos": 393, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DEEPVKKRSRKARGRGTPSS", "down_seq": "DSEPEGELGKEGKKLAKKSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser393" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q3UMU9-1.391.391", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q3UMU9-1.392.392", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3UMU9-1.395.395", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.395.395", "start_pos": 395, "end_pos": 395, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPVKKRSRKARGRGTPSSSD", "down_seq": "EPEGELGKEGKKLAKKSQLP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser395" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q3UMU9-1.391.391", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q3UMU9-1.392.392", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q3UMU9-1.393.393", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.450.450", "start_pos": 450, "end_pos": 450, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GRPDEKPRARPVKVERTRKR", "down_seq": "EGLSLERKGEKKKEPSVEER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser450" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "Q3UMU9-1.454.454", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.454.454", "start_pos": 454, "end_pos": 454, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EKPRARPVKVERTRKRSEGL", "down_seq": "LERKGEKKKEPSVEERLQKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "site_lbl": "Ser454" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q3UMU9-1.450.450", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3UMU9-1.620.620", "start_pos": 620, "end_pos": 620, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EATSQKGENMEDRAQEDGQD", "down_seq": "EDGPRGGSSEELHDSPRDNS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser620" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q3UMU9-1.628.628", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q3UMU9-1.629.629", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q3UMU9-1.635.635", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q3UMU9-1.640.640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.628.628", "start_pos": 628, "end_pos": 628, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NMEDRAQEDGQDSEDGPRGG", "down_seq": "SEELHDSPRDNSDPAKPGNE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser628" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q3UMU9-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q3UMU9-1.629.629", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q3UMU9-1.635.635", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q3UMU9-1.640.640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.629.629", "start_pos": 629, "end_pos": 629, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MEDRAQEDGQDSEDGPRGGS", "down_seq": "EELHDSPRDNSDPAKPGNER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser629" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q3UMU9-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q3UMU9-1.628.628", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q3UMU9-1.635.635", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q3UMU9-1.640.640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.635.635", "start_pos": 635, "end_pos": 635, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDGQDSEDGPRGGSSEELHD", "down_seq": "PRDNSDPAKPGNERQDHERT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser635" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q3UMU9-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q3UMU9-1.628.628", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q3UMU9-1.629.629", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q3UMU9-1.640.640", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.640.640", "start_pos": 640, "end_pos": 640, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SEDGPRGGSSEELHDSPRDN", "down_seq": "DPAKPGNERQDHERTRLASE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser640" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q3UMU9-1.620.620", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q3UMU9-1.628.628", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q3UMU9-1.629.629", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q3UMU9-1.635.635", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q3UMU9-1.659.659", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.659.659", "start_pos": 659, "end_pos": 659, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "NSDPAKPGNERQDHERTRLA", "down_seq": "ESANDDNEDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser659" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q3UMU9-1.640.640", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3UMU9-1.661.661", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q3UMU9-1.669.669", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.661.661", "start_pos": 661, "end_pos": 661, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPAKPGNERQDHERTRLASE", "down_seq": "ANDDNEDS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser661" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q3UMU9-1.659.659", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q3UMU9-1.669.669", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3UMU9-1.669.669", "start_pos": 669, "end_pos": 669, "uniprot_canonical_ac": "Q3UMU9-1", "length": 669, "uniprot_id": "HDGR2_MOUSE", "protein_name": "Hepatoma-derived growth factor-related protein 2", "refseq_ac": "NP_001291713", "refseq_name": "hepatoma-derived growth factor-related protein 2 isoform 1", "gene_name": "Hdgfl2", "gene_names_uniprotkb": "Hdgfl2; Hdgfrp2", "gene_names_refseq": "HRP-2; Hdgfl2; Hdgfrp2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RQDHERTRLASESANDDNED", "down_seq": "", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3UMU9", "url": "https://www.uniprot.org/uniprotkb/Q3UMU9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3UMU9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3UMU9" } ], "site_lbl": "Ser669" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "523", "end_pos": "524" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "114", "end_pos": "114" }, { "start_pos": "137", "end_pos": "137" }, { "start_pos": "165", "end_pos": "165" }, { "start_pos": "229", "end_pos": "229" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "239", "end_pos": "239" }, { "start_pos": "268", "end_pos": "268" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "367", "end_pos": "367" }, { "start_pos": "391", "end_pos": "391" }, { "start_pos": "392", "end_pos": "392" }, { "start_pos": "393", "end_pos": "393" }, { "start_pos": "395", "end_pos": "395" }, { "start_pos": "450", "end_pos": "450" }, { "start_pos": "454", "end_pos": "454" }, { "start_pos": "620", "end_pos": "620" }, { "start_pos": "628", "end_pos": "628" }, { "start_pos": "629", "end_pos": "629" }, { "start_pos": "635", "end_pos": "635" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "659", "end_pos": "659" }, { "start_pos": "661", "end_pos": "661" }, { "start_pos": "669", "end_pos": "669" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q3UMU9-1.659.659", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q3UMU9-1.661.661", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CGP1-1.113.113", "start_pos": 113, "end_pos": 113, "uniprot_canonical_ac": "Q8CGP1-1", "length": 126, "uniprot_id": "H2B1K_MOUSE", "protein_name": "Histone H2B type 1-K", "refseq_ac": "NP_783596", "refseq_name": "histone H2B type 1-K", "gene_name": "H2bc12", "gene_names_uniprotkb": "H2bc12; Hist1h2bk", "gene_names_refseq": "H2bc12; Hist1h2bk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "REIQTAVRLLLPGELAKHAV", "down_seq": "EGTKAVTKYTSAK", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "Q8CGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q8CGP1-1.116.116", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CGP1-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8CGP1-1", "length": 126, "uniprot_id": "H2B1K_MOUSE", "protein_name": "Histone H2B type 1-K", "refseq_ac": "NP_783596", "refseq_name": "histone H2B type 1-K", "gene_name": "H2bc12", "gene_names_uniprotkb": "H2bc12; Hist1h2bk", "gene_names_refseq": "H2bc12; Hist1h2bk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8CGP1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CGP1" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CGP1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CGP1", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q8CGP1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8CGP1" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "Q8CGP1-1.15.15", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CGP1-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "Q8CGP1-1", "length": 126, "uniprot_id": "H2B1K_MOUSE", "protein_name": "Histone H2B type 1-K", "refseq_ac": "NP_783596", "refseq_name": "histone H2B type 1-K", "gene_name": "H2bc12", "gene_names_uniprotkb": "H2bc12; Hist1h2bk", "gene_names_refseq": "H2bc12; Hist1h2bk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QTAVRLLLPGELAKHAVSEG", "down_seq": "KAVTKYTSAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" } ], "site_lbl": "Thr116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q8CGP1-1.113.113", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CGP1-1.15.15", "start_pos": 15, "end_pos": 15, "uniprot_canonical_ac": "Q8CGP1-1", "length": 126, "uniprot_id": "H2B1K_MOUSE", "protein_name": "Histone H2B type 1-K", "refseq_ac": "NP_783596", "refseq_name": "histone H2B type 1-K", "gene_name": "H2bc12", "gene_names_uniprotkb": "H2bc12; Hist1h2bk", "gene_names_refseq": "H2bc12; Hist1h2bk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation of histone H2B at DNA double-strand breaks.", "journal": "The Journal of experimental medicine", "date": "2004", "authors": "Fernandez-Capetillo O, Allis CD, Nussenzweig A", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" }, { "database": "iPTMnet", "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1" } ], "reference": [ { "type": "PubMed", "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225" } ] }, { "title": "Histone modifications associated with somatic hypermutation.", "journal": "Immunity", "date": "2005", "authors": "Odegard VH, Kim ST, Anderson SM, Shlomchik MJ, Schatz DG", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" }, { "database": "iPTMnet", "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1" } ], "reference": [ { "type": "PubMed", "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583" } ] } ], "crossref": [ { "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPEPAKSAPAPKKG", "down_seq": "KKAVTKAQKKDGKKRKRSRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by STK4/MST1", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" }, { "database": "iPTMnet", "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1" }, { "database": "PubMed", "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225" }, { "database": "PubMed", "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583" } ], "site_lbl": "Ser15" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8CGP1-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CGP1-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "Q8CGP1-1", "length": 126, "uniprot_id": "H2B1K_MOUSE", "protein_name": "Histone H2B type 1-K", "refseq_ac": "NP_783596", "refseq_name": "histone H2B type 1-K", "gene_name": "H2bc12", "gene_names_uniprotkb": "H2bc12; Hist1h2bk", "gene_names_refseq": "H2bc12; Hist1h2bk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis.", "journal": "Molecular cell", "date": "2020", "authors": "Huang D, Camacho CV, Setlem R, Ryu KW, Parameswaran B, Gupta RK, Kraus WL", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" }, { "database": "iPTMnet", "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1" } ], "reference": [ { "type": "PubMed", "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587" } ] }, { "title": "Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation.", "journal": "Science (New York, N.Y.)", "date": "2010", "authors": "Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" }, { "database": "iPTMnet", "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1" } ], "reference": [ { "type": "PubMed", "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423" } ] } ], "crossref": [ { "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KAVTKAQKKDGKKRKRSRKE", "down_seq": "YSVYVYKVLKQVHPDTGISS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by AMPK", "evidence": [ { "database": "UniProtKB", "id": "Q8CGP1", "url": "https://www.uniprot.org/uniprotkb/Q8CGP1" }, { "database": "iPTMnet", "id": "Q8CGP1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CGP1" }, { "database": "PubMed", "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587" }, { "database": "PubMed", "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423" } ], "site_lbl": "Ser37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZQ8-2.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q9QZQ8-2", "length": 369, "uniprot_id": "H2AY_MOUSE", "protein_name": "Core histone macro-H2A.1", "refseq_ac": "NP_001152985", "refseq_name": "core histone macro-H2A.1 isoform 2", "gene_name": "Macroh2a1", "gene_names_uniprotkb": "Macroh2a1; H2afy", "gene_names_refseq": "H2AF12M; H2afy; Macroh2a1; mH2a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9QZQ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9QZQ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9QZQ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QZQ8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QZQ8", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "Q9QZQ8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9QZQ8" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "224", "end_pos": "224" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZQ8-2.224.224", "start_pos": 224, "end_pos": 224, "uniprot_canonical_ac": "Q9QZQ8-2", "length": 369, "uniprot_id": "H2AY_MOUSE", "protein_name": "Core histone macro-H2A.1", "refseq_ac": "NP_001152985", "refseq_name": "core histone macro-H2A.1 isoform 2", "gene_name": "Macroh2a1", "gene_names_uniprotkb": "Macroh2a1; H2afy", "gene_names_refseq": "H2AF12M; H2afy; Macroh2a1; mH2a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD(+) consumption.", "journal": "Nature structural & molecular biology", "date": "2017", "authors": "Posavec Marjanovic M, Hurtado-Bages S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "28991266", "url": "https://glygen.org/publication/PubMed/28991266" } ] } ], "crossref": [ { "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "28991266", "url": "https://glygen.org/publication/PubMed/28991266", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "IASIDSDAVVHPTNTDFYTG", "down_seq": "EVGNTLEKKGGKEFVEAVLE", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "E", "comment": "Abolished ability to bind poly-ADP-ribose and inhibit PARP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "PubMed", "id": "28991266", "url": "https://glygen.org/publication/PubMed/28991266" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "224", "end_pos": "224" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZQ8-2.129.129", "start_pos": 129, "end_pos": 129, "uniprot_canonical_ac": "Q9QZQ8-2", "length": 369, "uniprot_id": "H2AY_MOUSE", "protein_name": "Core histone macro-H2A.1", "refseq_ac": "NP_001152985", "refseq_name": "core histone macro-H2A.1 isoform 2", "gene_name": "Macroh2a1", "gene_names_uniprotkb": "Macroh2a1; H2afy", "gene_names_refseq": "H2AF12M; H2afy; Macroh2a1; mH2a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IHPELLAKKRGSKGKLEAII", "down_seq": "PPPAKKAKSPSQKKPVAKKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "site_lbl": "Thr129" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "224", "end_pos": "224" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZQ8-2.170.170", "start_pos": 170, "end_pos": 170, "uniprot_canonical_ac": "Q9QZQ8-2", "length": 369, "uniprot_id": "H2AY_MOUSE", "protein_name": "Core histone macro-H2A.1", "refseq_ac": "NP_001152985", "refseq_name": "core histone macro-H2A.1 isoform 2", "gene_name": "Macroh2a1", "gene_names_uniprotkb": "Macroh2a1; H2afy", "gene_names_refseq": "H2AF12M; H2afy; Macroh2a1; mH2a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGKKGARKSKKKQGEVSKAA", "down_seq": "ADSTTEGTPTDGFTVLSTKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "site_lbl": "Ser170" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "224", "end_pos": "224" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q9QZQ8-2.173.173", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q9QZQ8-2.178.178", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZQ8-2.173.173", "start_pos": 173, "end_pos": 173, "uniprot_canonical_ac": "Q9QZQ8-2", "length": 369, "uniprot_id": "H2AY_MOUSE", "protein_name": "Core histone macro-H2A.1", "refseq_ac": "NP_001152985", "refseq_name": "core histone macro-H2A.1 isoform 2", "gene_name": "Macroh2a1", "gene_names_uniprotkb": "Macroh2a1; H2afy", "gene_names_refseq": "H2AF12M; H2afy; Macroh2a1; mH2a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KGARKSKKKQGEVSKAASAD", "down_seq": "TTEGTPTDGFTVLSTKSLFL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "site_lbl": "Ser173" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "224", "end_pos": "224" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q9QZQ8-2.170.170", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q9QZQ8-2.178.178", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q9QZQ8-2.178.178", "start_pos": 178, "end_pos": 178, "uniprot_canonical_ac": "Q9QZQ8-2", "length": 369, "uniprot_id": "H2AY_MOUSE", "protein_name": "Core histone macro-H2A.1", "refseq_ac": "NP_001152985", "refseq_name": "core histone macro-H2A.1 isoform 2", "gene_name": "Macroh2a1", "gene_names_uniprotkb": "Macroh2a1; H2afy", "gene_names_refseq": "H2AF12M; H2afy; Macroh2a1; mH2a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SKKKQGEVSKAASADSTTEG", "down_seq": "PTDGFTVLSTKSLFLGQKLQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9QZQ8", "url": "https://www.uniprot.org/uniprotkb/Q9QZQ8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q9QZQ8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9QZQ8" } ], "site_lbl": "Thr178" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "224", "end_pos": "224" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "129", "end_pos": "129" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "173", "end_pos": "173" }, { "start_pos": "178", "end_pos": "178" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q9QZQ8-2.170.170", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q9QZQ8-2.173.173", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O54879-1.133.133", "start_pos": 133, "end_pos": 133, "uniprot_canonical_ac": "O54879-1", "length": 200, "uniprot_id": "HMGB3_MOUSE", "protein_name": "High mobility group protein B3", "refseq_ac": "NP_001280552", "refseq_name": "high mobility group protein B3 isoform 1", "gene_name": "Hmgb3", "gene_names_uniprotkb": "Hmgb3; Hmg2a; Hmg4", "gene_names_refseq": "Hmg2a; Hmg4; Hmgb3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O54879", "url": "https://www.uniprot.org/uniprotkb/O54879" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "STNPGISIGDVAKKLGEMWN", "down_seq": "LSDNEKQPYVTKAAKLKEKY", "glycosylation": [ { "glytoucan_ac": "G07755XJ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "KLGEMWNNLSDNEK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn133", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "133", "end_pos": "133" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O54879-1.98.98", "start_pos": 98, "end_pos": 98, "uniprot_canonical_ac": "O54879-1", "length": 200, "uniprot_id": "HMGB3_MOUSE", "protein_name": "High mobility group protein B3", "refseq_ac": "NP_001280552", "refseq_name": "high mobility group protein B3 isoform 1", "gene_name": "Hmgb3", "gene_names_uniprotkb": "Hmgb3; Hmg2a; Hmg4", "gene_names_refseq": "Hmg2a; Hmg4; Hmgb3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O54879", "url": "https://www.uniprot.org/uniprotkb/O54879" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O54879", "url": "https://www.uniprot.org/uniprotkb/O54879", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YGPAKGGKKKKDPNAPKRPP", "down_seq": "GFFLFCSEFRPKIKSTNPGI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O54879", "url": "https://www.uniprot.org/uniprotkb/O54879" } ], "site_lbl": "Ser98" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "133", "end_pos": "133" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "98", "end_pos": "98" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P58406-1.11.11", "start_pos": 11, "end_pos": 11, "uniprot_canonical_ac": "P58406-1", "length": 445, "uniprot_id": "HRH3_MOUSE", "protein_name": "Histamine H3 receptor", "refseq_ac": "NP_598610", "refseq_name": "histamine H3 receptor isoform 1", "gene_name": "Hrh3", "gene_names_uniprotkb": "Hrh3", "gene_names_refseq": "Eae8; H3R; HH3R; Hrh3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MERAPPDGLM", "down_seq": "ASGALAGEAAAAGGARGFSA", "glycosylation": [ { "glytoucan_ac": "G25079LO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "APPDGLMNASGALAGEAAAAGGAR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn11", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn11", "evidence": [ { "id": "P58406", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P58406#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "304", "end_pos": "304" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "439", "end_pos": "439" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P58406-1.304.304", "start_pos": 304, "end_pos": 304, "uniprot_canonical_ac": "P58406-1", "length": 445, "uniprot_id": "HRH3_MOUSE", "protein_name": "Histamine H3 receptor", "refseq_ac": "NP_598610", "refseq_name": "histamine H3 receptor isoform 1", "gene_name": "Hrh3", "gene_names_uniprotkb": "Hrh3", "gene_names_refseq": "Eae8; H3R; HH3R; Hrh3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VETGEAGLGGGSGGGAAASP", "down_seq": "SSSGSSSRGTERPRSLKRGS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "304", "end_pos": "304" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "439", "end_pos": "439" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P58406-1.439.439", "start_pos": 439, "end_pos": 439, "uniprot_canonical_ac": "P58406-1", "length": 445, "uniprot_id": "HRH3_MOUSE", "protein_name": "Histamine H3 receptor", "refseq_ac": "NP_598610", "refseq_name": "histamine H3 receptor isoform 1", "gene_name": "Hrh3", "gene_names_uniprotkb": "Hrh3", "gene_names_refseq": "Eae8; H3R; HH3R; Hrh3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406" }, { "database": "iPTMnet", "id": "P58406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P58406" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P58406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P58406", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FRRAFTKLLCPQKLKVQPHG", "down_seq": "LEQCWK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P58406", "url": "https://www.uniprot.org/uniprotkb/P58406" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P58406", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P58406" } ], "site_lbl": "Ser439" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "11", "end_pos": "11" }, { "start_pos": "304", "end_pos": "304" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "439", "end_pos": "439" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.380.380", "start_pos": 380, "end_pos": 380, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.", "journal": "The Journal of biological chemistry", "date": "2003-10-31", "authors": "Much Barbara, Wahl-Schott Christian, Zong Xiangang, Schneider Angela, Baumann Ludwig, Moosmang Sven, Ludwig Andreas, Biel Martin", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703#ptm_processing" }, { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "12928435", "url": "https://glygen.org/publication/PubMed/12928435" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12928435", "url": "https://glygen.org/publication/PubMed/12928435", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LVPMLQDFPSDCWVSINNMV", "down_seq": "HSWSELYSFALFKAMSHMLC", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn380", "evidence": [ { "id": "O88703", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O88703#ptm_processing" }, { "id": "12928435", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/12928435" } ] } ], "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "Q", "comment": "Abolishes cell membrane localization.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "12928435", "url": "https://glygen.org/publication/PubMed/12928435" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "glycosylation_flag", "mutagenesis_flag" ], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PPPPAPPQPQPPPAPPPNPT", "down_seq": "PSHPESADEPGPRARLCSRD", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88703-1.696.696", "start_pos": 696, "end_pos": 696, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "database": "O-GlcNAc Atlas", "id": "O88703", "url": "https://oglcnac.org/atlas/detail/O88703" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQAELGQRVGLFPPPPPPQV", "down_seq": "SAIATLQQAVAMSFCPQVAR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr696", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "O88703", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "O88703-1.697.697", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88703-1.701.701", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.697.697", "start_pos": 697, "end_pos": 697, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "database": "O-GlcNAc Atlas", "id": "O88703", "url": "https://oglcnac.org/atlas/detail/O88703" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QAELGQRVGLFPPPPPPQVT", "down_seq": "AIATLQQAVAMSFCPQVARP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser697", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "O88703", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "O88703-1.696.696", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88703-1.701.701", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.701.701", "start_pos": 701, "end_pos": 701, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "database": "O-GlcNAc Atlas", "id": "O88703", "url": "https://oglcnac.org/atlas/detail/O88703" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GQRVGLFPPPPPPQVTSAIA", "down_seq": "LQQAVAMSFCPQVARPLVGP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr701", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "O88703", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "O88703-1.696.696", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88703-1.697.697", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.763.763", "start_pos": 763, "end_pos": 763, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "database": "O-GlcNAc Atlas", "id": "O88703", "url": "https://oglcnac.org/atlas/detail/O88703" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "https://oglcnac.org/atlas/detail/O88703", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SPGPPAASPPAAPSSPRAPR", "down_seq": "SPYGVPGSPATRVGPALPAR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr763", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "O88703", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88703" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "O88703", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88703" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "O88703-1.743.743", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88703-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.757.757", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.225.225", "start_pos": 225, "end_pos": 225, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "GITFFKDETTAPWIVFNVVS", "down_seq": "TFFLMDLVLNFRTGIVIEDN", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Abolishes surface expression and channel activity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "O88703-1.231.231", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.231.231", "start_pos": 231, "end_pos": 231, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "DETTAPWIVFNVVSDTFFLM", "down_seq": "LVLNFRTGIVIEDNTEIILD", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduces surface expression and abolishes channel activity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "O88703-1.225.225", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.267.267", "start_pos": 267, "end_pos": 267, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "EIILDPEKIKKKYLRTWFVV", "down_seq": "FVSSIPVDYIFLIVEKGIDS", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduces surface expression and abolishes channel activity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "O88703-1.275.275", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.275.275", "start_pos": 275, "end_pos": 275, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "IKKKYLRTWFVVDFVSSIPV", "down_seq": "YIFLIVEKGIDSEVYKTARA", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "N", "comment": "Reduces surface expression and abolishes channel activity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "O88703-1.267.267", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "SIPVDYIFLIVEKGIDSEVY", "down_seq": "TARALRIVRFTKILSLLRLL", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "Q", "comment": "Shifts voltage dependence of activation to more negative values.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O88703-1.275.275", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.294.294", "start_pos": 294, "end_pos": 294, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "VDYIFLIVEKGIDSEVYKTA", "down_seq": "ALRIVRFTKILSLLRLLRLS", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Shifts voltage dependence of activation to more negative values.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88703-1.275.275", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.297.297", "start_pos": 297, "end_pos": 297, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "IFLIVEKGIDSEVYKTARAL", "down_seq": "IVRFTKILSLLRLLRLSRLI", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Shifts voltage dependence of activation to more negative values.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.300.300", "start_pos": 300, "end_pos": 300, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "IVEKGIDSEVYKTARALRIV", "down_seq": "FTKILSLLRLLRLSRLIRYI", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Shifts voltage dependence of activation to more negative values.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.303.303", "start_pos": 303, "end_pos": 303, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KGIDSEVYKTARALRIVRFT", "down_seq": "ILSLLRLLRLSRLIRYIHQW", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "Q", "comment": "Decreases current amplitude.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.306.306", "start_pos": 306, "end_pos": 306, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Pacemaker channels produce an instantaneous current.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Proenza C, Angoli D, Agranovich E, Macri V, Accili EA", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "11741901", "url": "https://glygen.org/publication/PubMed/11741901" } ] }, { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11741901", "url": "https://glygen.org/publication/PubMed/11741901", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DSEVYKTARALRIVRFTKIL", "down_seq": "LLRLLRLSRLIRYIHQWEEI", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "Q", "comment": "Decreases current amplitude.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11741901", "url": "https://glygen.org/publication/PubMed/11741901" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.309.309", "start_pos": 309, "end_pos": 309, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "VYKTARALRIVRFTKILSLL", "down_seq": "LLRLSRLIRYIHQWEEIFHM", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Abolishes surface expression and channel activity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.291.291", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.312.312", "start_pos": 312, "end_pos": 312, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "TARALRIVRFTKILSLLRLL", "down_seq": "LSRLIRYIHQWEEIFHMTYD", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Reduces surface expression and decreases current amplitude.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.294.294", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88703-1.331.331", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "ALRIVRFTKILSLLRLLRLS", "down_seq": "LIRYIHQWEEIFHMTYDLAS", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Reduces surface expression and abolishes channel activity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.297.297", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O88703-1.331.331", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The S4-S5 linker couples voltage sensing and activation of pacemaker channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001", "authors": "Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] }, { "title": "Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Chen J, Mitcheson JS, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787", "database": "PubMed", "categories": [ "Other" ] }, { "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "IVRFTKILSLLRLLRLSRLI", "down_seq": "YIHQWEEIFHMTYDLASAVM", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Reduces surface expression and disrupts channel closure.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" }, { "database": "PubMed", "id": "10962006", "url": "https://glygen.org/publication/PubMed/10962006" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.300.300", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88703-1.331.331", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.321.321", "start_pos": 321, "end_pos": 321, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A single histidine residue determines the pH sensitivity of the pacemaker channel HCN2.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Zong X, Stieber J, Ludwig A, Hofmann F, Biel M", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "11096117", "url": "https://glygen.org/publication/PubMed/11096117" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11096117", "url": "https://glygen.org/publication/PubMed/11096117", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "FTKILSLLRLLRLSRLIRYI", "down_seq": "QWEEIFHMTYDLASAVMRIC", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "E", "comment": "Shifts voltage dependence of activation to more positive values and abolishes pH-sensitivity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11096117", "url": "https://glygen.org/publication/PubMed/11096117" } ] }, { "sequence_org": "H", "sequence_mut": "Q", "comment": "Abolishes pH-sensitivity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11096117", "url": "https://glygen.org/publication/PubMed/11096117" } ] }, { "sequence_org": "H", "sequence_mut": "R", "comment": "Abolishes pH-sensitivity.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11096117", "url": "https://glygen.org/publication/PubMed/11096117" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88703-1.331.331", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "O88703-1.339.339", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.324.324", "start_pos": 324, "end_pos": 324, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The S4-S5 linker couples voltage sensing and activation of pacemaker channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001", "authors": "Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "ILSLLRLLRLSRLIRYIHQW", "down_seq": "EIFHMTYDLASAVMRICNLI", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "Q", "comment": "Disrupts channel closure.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.306.306", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.309.309", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "downstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88703-1.331.331", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88703-1.339.339", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.331.331", "start_pos": 331, "end_pos": 331, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The S4-S5 linker couples voltage sensing and activation of pacemaker channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001", "authors": "Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LRLSRLIRYIHQWEEIFHMT", "down_seq": "DLASAVMRICNLISMMLLLC", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Disrupts channel closure.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] }, { "sequence_org": "Y", "sequence_mut": "S", "comment": "Disrupts channel closure.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88703-1.312.312", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "downstream", "id": "O88703-1.315.315", "categories": [ "mutagenesis_flag" ] }, { "distance": 13, "direction": "downstream", "id": "O88703-1.318.318", "categories": [ "mutagenesis_flag" ] }, { "distance": 10, "direction": "downstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88703-1.339.339", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.339.339", "start_pos": 339, "end_pos": 339, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The S4-S5 linker couples voltage sensing and activation of pacemaker channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001", "authors": "Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "YIHQWEEIFHMTYDLASAVM", "down_seq": "ICNLISMMLLLCHWDGCLQF", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "Q", "comment": "Disrupts channel closure.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "11553787", "url": "https://glygen.org/publication/PubMed/11553787" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "O88703-1.321.321", "categories": [ "mutagenesis_flag" ] }, { "distance": 15, "direction": "downstream", "id": "O88703-1.324.324", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "downstream", "id": "O88703-1.331.331", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.594.594", "start_pos": 594, "end_pos": 594, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Local and global interpretations of a disease-causing mutation near the ligand entry path in hyperpolarization-activated cAMP-gated channel.", "journal": "Structure (London, England : 1993)", "date": "2012", "authors": "Xu X, Marni F, Wu S, Su Z, Musayev F, Shrestha S, Xie C, Gao W, Liu Q, Zhou L", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "23103389", "url": "https://glygen.org/publication/PubMed/23103389" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "23103389", "url": "https://glygen.org/publication/PubMed/23103389", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LSDGSYFGEICLLTRGRRTA", "down_seq": "VRADTYCRLYSLSVDNFNEV", "mutagenesis": [ { "sequence_org": "S", "sequence_mut": "R", "comment": "Shifts channel activation to more negative voltage, slows channel opening and speeds up channel closure. Reduces sensitivity to activation by cAMP.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "23103389", "url": "https://glygen.org/publication/PubMed/23103389" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.671.671", "start_pos": 671, "end_pos": 671, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A high affinity switch for cAMP in the HCN pacemaker channels.", "journal": "Nature communications", "date": "2024-01-29", "authors": "Porro Alessandro, Saponaro Andrea, Castelli Roberta, Introini Bianca, Hafez Alkotob Anahita, Ranjbari Golnaz, Enke Uta, Kusch Jana, Benndorf Klaus, Santoro Bina, DiFrancesco Dario, Thiel Gerhard, Moroni Anna", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "reference": [ { "type": "PubMed", "id": "38287019", "url": "https://glygen.org/publication/PubMed/38287019" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "38287019", "url": "https://glygen.org/publication/PubMed/38287019", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "LSSGVFNNQENAIIQEIVKY", "down_seq": "REMVQQAELGQRVGLFPPPP", "mutagenesis": [ { "sequence_org": "D", "sequence_mut": "A", "comment": "Reduced the response to cAMP.", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "38287019", "url": "https://glygen.org/publication/PubMed/38287019" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.119.119", "start_pos": 119, "end_pos": 119, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KVSFSCRGAASGPSAAEEAG", "down_seq": "EEAGPAGEPRGSQASFLQRQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "site_lbl": "Ser119" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "O88703-1.134.134", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.134.134", "start_pos": 134, "end_pos": 134, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AEEAGSEEAGPAGEPRGSQA", "down_seq": "FLQRQFGALLQPGVNKFSLR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "site_lbl": "Ser134" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O88703-1.119.119", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88703-1.641.641", "start_pos": 641, "end_pos": 641, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.", "journal": "PloS one", "date": "2011", "authors": "Hammelmann V, Zong X, Hofmann F, Michalakis S, Biel M", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MRRAFETVAIDRLDRIGKKN", "down_seq": "ILLHKVQHDLSSGVFNNQEN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKG/PRKG2", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" }, { "database": "PubMed", "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269" } ], "site_lbl": "Ser641" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.726.726", "start_pos": 726, "end_pos": 726, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VAMSFCPQVARPLVGPLALG", "down_seq": "PRLVRRAPPGPLPPAASPGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "site_lbl": "Ser726" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "O88703-1.743.743", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O88703-1.743.743", "start_pos": 743, "end_pos": 743, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALGSPRLVRRAPPGPLPPAA", "down_seq": "PGPPAASPPAAPSSPRAPRT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "site_lbl": "Ser743" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O88703-1.726.726", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88703-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88703-1.757.757", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "O88703-1.763.763", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.750.750", "start_pos": 750, "end_pos": 750, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VRRAPPGPLPPAASPGPPAA", "down_seq": "PPAAPSSPRAPRTSPYGVPG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "site_lbl": "Ser750" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "O88703-1.743.743", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88703-1.757.757", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "O88703-1.763.763", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.757.757", "start_pos": 757, "end_pos": 757, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PLPPAASPGPPAASPPAAPS", "down_seq": "PRAPRTSPYGVPGSPATRVG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "site_lbl": "Ser757" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "O88703-1.743.743", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88703-1.750.750", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88703-1.763.763", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.786.786", "start_pos": 786, "end_pos": 786, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.", "journal": "PloS one", "date": "2011", "authors": "Hammelmann V, Zong X, Hofmann F, Michalakis S, Biel M", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269" } ] } ], "crossref": [ { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YGVPGSPATRVGPALPARRL", "down_seq": "RASRPLSASQPSLPHGVPAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" }, { "database": "PubMed", "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269" } ], "site_lbl": "Ser786" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.840.840", "start_pos": 840, "end_pos": 840, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.", "journal": "PloS one", "date": "2011", "authors": "Hammelmann V, Zong X, Hofmann F, Michalakis S, Biel M", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRLGPAPTARTAAPSPDRRD", "down_seq": "ASPGAASGLDPLDSARSRLS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" }, { "database": "PubMed", "id": "21347269", "url": "https://glygen.org/publication/PubMed/21347269" } ], "site_lbl": "Ser840" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "O88703-1.842.842", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88703-1.847.847", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.842.842", "start_pos": 842, "end_pos": 842, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LGPAPTARTAAPSPDRRDSA", "down_seq": "PGAASGLDPLDSARSRLSSN", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "site_lbl": "Ser842" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "O88703-1.840.840", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88703-1.847.847", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "O88703-1.861.861", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.847.847", "start_pos": 847, "end_pos": 847, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TARTAAPSPDRRDSASPGAA", "down_seq": "GLDPLDSARSRLSSNL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "site_lbl": "Ser847" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "O88703-1.840.840", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88703-1.842.842", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O88703-1.861.861", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88703-1.861.861", "start_pos": 861, "end_pos": 861, "uniprot_canonical_ac": "O88703-1", "length": 863, "uniprot_id": "HCN2_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "refseq_ac": "NP_032252", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2", "gene_name": "Hcn2", "gene_names_uniprotkb": "Hcn2; Bcng2; Hac1", "gene_names_refseq": "BCNG2; HAC1; Hcn2; trls", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88703", "url": "https://www.uniprot.org/uniprotkb/O88703" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Regulation of HCN2 Current by PI3K/Akt Signaling.", "journal": "Frontiers in physiology", "date": "2020", "authors": "Lu Zhongju, Wang Hong Zhan, Gordon Chris R, Ballou Lisa M, Lin Richard Z, Cohen Ira S", "evidence": [ { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" } ], "reference": [ { "type": "PubMed", "id": "33240105", "url": "https://glygen.org/publication/PubMed/33240105" } ] } ], "crossref": [ { "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "33240105", "url": "https://glygen.org/publication/PubMed/33240105", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ASPGAASGLDPLDSARSRLS", "down_seq": "NL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O88703", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O88703" }, { "database": "PubMed", "id": "33240105", "url": "https://glygen.org/publication/PubMed/33240105" } ], "site_lbl": "Ser861" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "380", "end_pos": "380" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "696", "end_pos": "696" }, { "start_pos": "697", "end_pos": "697" }, { "start_pos": "701", "end_pos": "701" }, { "start_pos": "763", "end_pos": "763" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "267", "end_pos": "267" }, { "start_pos": "275", "end_pos": "275" }, { "start_pos": "291", "end_pos": "291" }, { "start_pos": "294", "end_pos": "294" }, { "start_pos": "297", "end_pos": "297" }, { "start_pos": "300", "end_pos": "300" }, { "start_pos": "303", "end_pos": "303" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "312", "end_pos": "312" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "324", "end_pos": "324" }, { "start_pos": "331", "end_pos": "331" }, { "start_pos": "339", "end_pos": "339" }, { "start_pos": "380", "end_pos": "380" }, { "start_pos": "594", "end_pos": "594" }, { "start_pos": "671", "end_pos": "671" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "119", "end_pos": "119" }, { "start_pos": "134", "end_pos": "134" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "726", "end_pos": "726" }, { "start_pos": "743", "end_pos": "743" }, { "start_pos": "750", "end_pos": "750" }, { "start_pos": "757", "end_pos": "757" }, { "start_pos": "786", "end_pos": "786" }, { "start_pos": "840", "end_pos": "840" }, { "start_pos": "842", "end_pos": "842" }, { "start_pos": "847", "end_pos": "847" }, { "start_pos": "861", "end_pos": "861" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "O88703-1.842.842", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O88703-1.847.847", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.327.327", "start_pos": 327, "end_pos": 327, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1997", "authors": "Santoro B, Grant SG, Bartsch D, Kandel ER", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704#ptm_processing" }, { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "9405696", "url": "https://glygen.org/publication/PubMed/9405696" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9405696", "url": "https://glygen.org/publication/PubMed/9405696", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LVPLLQDFPPDCWVSLNEMV", "down_seq": "DSWGKQYSYALFKAMSHMLC", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn327", "evidence": [ { "id": "O88704", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O88704#ptm_processing" }, { "id": "9405696", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/9405696" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "O88704-1.318.318", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.634.634", "start_pos": 634, "end_pos": 634, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IVKHDREMVQAIPPINYPQM", "down_seq": "ALNCTSSTTTPTSRMRTQSP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr634", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "O88704", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.637.637", "start_pos": 637, "end_pos": 637, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "HDREMVQAIPPINYPQMTAL", "down_seq": "CTSSTTTPTSRMRTQSPPVY", "glycosylation": [ { "glytoucan_ac": "G10486CT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "EMVQAIPPINYPQMTALNCTSSTTTPTSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn637", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.639.639", "start_pos": 639, "end_pos": 639, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "REMVQAIPPINYPQMTALNC", "down_seq": "SSTTTPTSRMRTQSPPVYTA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr639", "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.640.640", "start_pos": 640, "end_pos": 640, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Age-related loss of neural stem cell O-GlcNAc promotes a glial fate switch through STAT3 activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2020", "authors": "White CW 3rd, Fan X, Maynard JC, Wheatley EG, Bieri G, Couthouis J, Burlingame AL, Villeda SA", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "32848054", "url": "https://glygen.org/publication/PubMed/32848054", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EMVQAIPPINYPQMTALNCT", "down_seq": "STTTPTSRMRTQSPPVYTAT", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser640", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "O88704", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "32848054", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32848054" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.641.641", "start_pos": 641, "end_pos": 641, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MVQAIPPINYPQMTALNCTS", "down_seq": "TTTPTSRMRTQSPPVYTATS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser641", "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.642.642", "start_pos": 642, "end_pos": 642, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VQAIPPINYPQMTALNCTSS", "down_seq": "TTPTSRMRTQSPPVYTATSL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr642", "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.643.643", "start_pos": 643, "end_pos": 643, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QAIPPINYPQMTALNCTSST", "down_seq": "TPTSRMRTQSPPVYTATSLS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr643", "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88704-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.644.644", "start_pos": 644, "end_pos": 644, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] } ], "crossref": [ { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AIPPINYPQMTALNCTSSTT", "down_seq": "PTSRMRTQSPPVYTATSLSH", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr644", "evidence": [ { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "O88704-1.634.634", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "O88704-1.637.637", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "O88704-1.639.639", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "O88704-1.640.640", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O88704-1.641.641", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O88704-1.642.642", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88704-1.643.643", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.792.792", "start_pos": 792, "end_pos": 792, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQQQPQTPGSSTPKNEVHKS", "down_seq": "QALHNTNLTKEVRPLSASQP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr792", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "O88704", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.828.828", "start_pos": 828, "end_pos": 828, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SASQPSLPHEVSTLISRPHP", "down_seq": "VGESLASIPQPVAAVHSTGL", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr828", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "O88704", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "O88704", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/O88704" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr828", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "O88704-1.835.835", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.835.835", "start_pos": 835, "end_pos": 835, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases.", "journal": "Frontiers in aging", "date": "2021", "authors": "Huynh Van N, Wang Sheng, Ouyang Xiaosen, Wani Willayat Y, Johnson Michelle S, Chacko Balu K, Jegga Anil G, Qian Wei-Jun, Chatham John C, Darley-Usmar Victor M, Zhang Jianhua", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "database": "O-GlcNAc Atlas", "id": "O88704", "url": "https://oglcnac.org/atlas/detail/O88704" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "35822049", "url": "https://glygen.org/publication/PubMed/35822049", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O88704", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PHEVSTLISRPHPTVGESLA", "down_seq": "IPQPVAAVHSTGLQAGSRST", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser835", "evidence": [ { "id": "35822049", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/35822049" }, { "id": "O88704", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O88704" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "O88704-1.828.828", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.303.303", "start_pos": 303, "end_pos": 303, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "An external determinant in the S5-P linker of the pacemaker (HCN) channel identified by sulfhydryl modification.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Xue T, Li RA", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "12351622", "url": "https://glygen.org/publication/PubMed/12351622" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12351622", "url": "https://glygen.org/publication/PubMed/12351622", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "AVVRIFNLIGMMLLLCHWDG", "down_seq": "LQFLVPLLQDFPPDCWVSLN", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes conductivity.", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" }, { "database": "PubMed", "id": "12351622", "url": "https://glygen.org/publication/PubMed/12351622" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "O88704-1.291.291", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O88704-1.318.318", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "An external determinant in the S5-P linker of the pacemaker (HCN) channel identified by sulfhydryl modification.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Xue T, Li RA", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "12351622", "url": "https://glygen.org/publication/PubMed/12351622" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12351622", "url": "https://glygen.org/publication/PubMed/12351622", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "CHWDGCLQFLVPLLQDFPPD", "down_seq": "WVSLNEMVNDSWGKQYSYAL", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes sensitivity to sulfhydryl modification.", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" }, { "database": "PubMed", "id": "12351622", "url": "https://glygen.org/publication/PubMed/12351622" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O88704-1.303.303", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "O88704-1.327.327", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.349.349", "start_pos": 349, "end_pos": 349, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization.", "journal": "Circulation research", "date": "2002", "authors": "Xue T, Marban E, Li RA", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "SWGKQYSYALFKAMSHMLCI", "down_seq": "YGAQAPVSMSDLWITMLSMI", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes conductivity; when associated with A-350 and A-351.", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" }, { "database": "PubMed", "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "O88704-1.350.350", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O88704-1.351.351", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.350.350", "start_pos": 350, "end_pos": 350, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization.", "journal": "Circulation research", "date": "2002", "authors": "Xue T, Marban E, Li RA", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "WGKQYSYALFKAMSHMLCIG", "down_seq": "GAQAPVSMSDLWITMLSMIV", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes conductivity; when associated with A-349 and A-351.", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" }, { "database": "PubMed", "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "O88704-1.349.349", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "O88704-1.351.351", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.351.351", "start_pos": 351, "end_pos": 351, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization.", "journal": "Circulation research", "date": "2002", "authors": "Xue T, Marban E, Li RA", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "GKQYSYALFKAMSHMLCIGY", "down_seq": "AQAPVSMSDLWITMLSMIVG", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes conductivity; when associated with A-349 and A-350.", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" }, { "database": "PubMed", "id": "12089064", "url": "https://glygen.org/publication/PubMed/12089064" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "O88704-1.349.349", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "O88704-1.350.350", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.538.538", "start_pos": 538, "end_pos": 538, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Lolicato M, Nardini M, Gazzarrini S, Moller S, Bertinetti D, Herberg FW, Bolognesi M, Martin H, Fasolini M, Bertrand JA, Arrigoni C, Thiel G, Moroni A", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "reference": [ { "type": "PubMed", "id": "22006928", "url": "https://glygen.org/publication/PubMed/22006928" } ] } ], "crossref": [ { "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22006928", "url": "https://glygen.org/publication/PubMed/22006928", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "EMKLTDGSYFGEICLLTKGR", "down_seq": "TASVRADTYCRLYSLSVDNF", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "E", "comment": "Reduces affinity for cAMP and impairs tetramerization.", "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" }, { "database": "PubMed", "id": "22006928", "url": "https://glygen.org/publication/PubMed/22006928" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O88704-1.291.291", "start_pos": 291, "end_pos": 291, "uniprot_canonical_ac": "O88704-1", "length": 910, "uniprot_id": "HCN1_MOUSE", "protein_name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "refseq_ac": "NP_034538", "refseq_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1", "gene_name": "Hcn1", "gene_names_uniprotkb": "Hcn1; Bcng1; Hac2", "gene_names_refseq": "Bcng1; C630013B14Rik; HAC2; Hcn1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O88704", "url": "https://www.uniprot.org/uniprotkb/O88704" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3404480023", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3404480023", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "EEIFHMTYDLASAVVRIFNL", "down_seq": "GMMLLLCHWDGCLQFLVPLL", "snv": [ { "evidence": [ { "id": "rs3404480023", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3404480023" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NLI->NLS).", "chr_id": "13", "chr_pos": "117946498", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I291", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "327", "end_pos": "327" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "637", "end_pos": "637" }, { "start_pos": "639", "end_pos": "639" }, { "start_pos": "640", "end_pos": "640" }, { "start_pos": "641", "end_pos": "641" }, { "start_pos": "642", "end_pos": "642" }, { "start_pos": "643", "end_pos": "643" }, { "start_pos": "644", "end_pos": "644" }, { "start_pos": "792", "end_pos": "792" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "835", "end_pos": "835" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "303", "end_pos": "303" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "349", "end_pos": "349" }, { "start_pos": "350", "end_pos": "350" }, { "start_pos": "351", "end_pos": "351" }, { "start_pos": "538", "end_pos": "538" } ] }, { "type": "snv", "site_list": [ { "start_pos": "291", "end_pos": "291" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "O88704-1.303.303", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52927-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P52927-1", "length": 108, "uniprot_id": "HMGA2_MOUSE", "protein_name": "High mobility group protein HMGI-C", "refseq_ac": "NP_001334099", "refseq_name": "high mobility group protein HMGI-C isoform 2", "gene_name": "Hmga2", "gene_names_uniprotkb": "Hmga2; Hmgic", "gene_names_refseq": "9430083A20Rik; HMGI-C; Hmga2; Hmgic; pg; pygmy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52927", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52927" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52927", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52927" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Zaro BW, Yang YY, Hang HC, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P52927", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52927" } ], "reference": [ { "type": "PubMed", "id": "21540332", "url": "https://glygen.org/publication/PubMed/21540332" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52927", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52927", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21540332", "url": "https://glygen.org/publication/PubMed/21540332", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "P52927", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P52927" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "21540332", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/21540332" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52927-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P52927-1", "length": 108, "uniprot_id": "HMGA2_MOUSE", "protein_name": "High mobility group protein HMGI-C", "refseq_ac": "NP_001334099", "refseq_name": "high mobility group protein HMGI-C isoform 2", "gene_name": "Hmga2", "gene_names_uniprotkb": "Hmga2; Hmgic", "gene_names_refseq": "9430083A20Rik; HMGI-C; Hmga2; Hmgic; pg; pygmy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" }, { "database": "iPTMnet", "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRKWPQQVVQKKPAQETEET", "down_seq": "SQESAEED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927" } ], "site_lbl": "Ser100" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P52927-1.104.104", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52927-1.104.104", "start_pos": 104, "end_pos": 104, "uniprot_canonical_ac": "P52927-1", "length": 108, "uniprot_id": "HMGA2_MOUSE", "protein_name": "High mobility group protein HMGI-C", "refseq_ac": "NP_001334099", "refseq_name": "high mobility group protein HMGI-C isoform 2", "gene_name": "Hmga2", "gene_names_uniprotkb": "Hmga2; Hmgic", "gene_names_refseq": "9430083A20Rik; HMGI-C; Hmga2; Hmgic; pg; pygmy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Sweet SM, Bailey CM, Cunningham DL, Heath JK, Cooper HJ", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" }, { "database": "iPTMnet", "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927" } ], "reference": [ { "type": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" }, { "database": "iPTMnet", "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQQVVQKKPAQETEETSSQE", "down_seq": "AEED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" }, { "database": "PubMed", "id": "19131326", "url": "https://glygen.org/publication/PubMed/19131326" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P52927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P52927" } ], "site_lbl": "Ser104" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P52927-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52927-1.40.40", "start_pos": 40, "end_pos": 40, "uniprot_canonical_ac": "P52927-1", "length": 108, "uniprot_id": "HMGA2_MOUSE", "protein_name": "High mobility group protein HMGI-C", "refseq_ac": "NP_001334099", "refseq_name": "high mobility group protein HMGI-C isoform 2", "gene_name": "Hmga2", "gene_names_uniprotkb": "Hmga2; Hmgic", "gene_names_refseq": "9430083A20Rik; HMGI-C; Hmga2; Hmgic; pg; pygmy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "AAPVPQKRGRGRPRKQQQEP", "down_seq": "CEPSPKRPRGRPKGSKNKSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "site_lbl": "Thr40" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P52927-1.44.44", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52927-1.44.44", "start_pos": 44, "end_pos": 44, "uniprot_canonical_ac": "P52927-1", "length": 108, "uniprot_id": "HMGA2_MOUSE", "protein_name": "High mobility group protein HMGI-C", "refseq_ac": "NP_001334099", "refseq_name": "high mobility group protein HMGI-C isoform 2", "gene_name": "Hmga2", "gene_names_uniprotkb": "Hmga2; Hmgic", "gene_names_refseq": "9430083A20Rik; HMGI-C; Hmga2; Hmgic; pg; pygmy", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQKRGRGRPRKQQQEPTCEP", "down_seq": "PKRPRGRPKGSKNKSPSKAA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P52927", "url": "https://www.uniprot.org/uniprotkb/P52927" } ], "site_lbl": "Ser44" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "104", "end_pos": "104" }, { "start_pos": "40", "end_pos": "40" }, { "start_pos": "44", "end_pos": "44" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P52927-1.40.40", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P00493", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P00493" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P00493", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P00493" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P00493", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P00493", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "P00493", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P00493" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P00493-1.2.2", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P00493-1.106.106", "start_pos": 106, "end_pos": 106, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3408042455", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3408042455", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "NRNSDRSIPMTVDFIRLKSY", "down_seq": "NDQSTGDIKVIGGDDLSTLT", "snv": [ { "evidence": [ { "id": "rs3408042455", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3408042455" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52091146", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C106", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "upstream", "id": "P00493-1.125.125", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.125.125", "start_pos": 125, "end_pos": 125, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389575140", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389575140", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "YCNDQSTGDIKVIGGDDLST", "down_seq": "TGKNVLIVEDIIDTGKTMQT", "snv": [ { "evidence": [ { "id": "rs3389575140", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389575140" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52097585", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L125", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P00493-1.106.106", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P00493-1.142.142", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.166.166", "start_pos": 166, "end_pos": 166, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389563951", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389563951", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "LLSLVKQYSPKMVKVASLLV", "down_seq": "RTSRSVGYRPDFVGFEIPDK", "snv": [ { "evidence": [ { "id": "rs3389563951", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389563951" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52108993", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K166", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P00493-1.171.171", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P00493-1.174.174", "categories": [ "snv_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P00493-1.184.184", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.171.171", "start_pos": 171, "end_pos": 171, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389568858", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389568858", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KQYSPKMVKVASLLVKRTSR", "down_seq": "VGYRPDFVGFEIPDKFVVGY", "snv": [ { "evidence": [ { "id": "rs3389568858", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389568858" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109008", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S171", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P00493-1.166.166", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P00493-1.174.174", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P00493-1.184.184", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P00493-1.187.187", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.174.174", "start_pos": 174, "end_pos": 174, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs1133176654", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133176654", "database": "dbSNP", "categories": [ "Other" ] }, { "id": "rs1132610450", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132610450", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SPKMVKVASLLVKRTSRSVG", "down_seq": "RPDFVGFEIPDKFVVGYALD", "snv": [ { "evidence": [ { "id": "rs1133176654", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1133176654" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109018", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y174", "keywords": [ "ebi", "germline" ] }, { "evidence": [ { "id": "rs1132610450", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1132610450" } ], "glycoeffect": [], "sequence_org": "Y", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109017", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y174", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "P00493-1.166.166", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P00493-1.171.171", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P00493-1.184.184", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P00493-1.187.187", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.17.17", "start_pos": 17, "end_pos": 17, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389526557", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389526557", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "MPTRSPSVVISDDEPG", "down_seq": "DLDLFCIPNHYAEDLEKVFI", "snv": [ { "evidence": [ { "id": "rs3389526557", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389526557" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "C", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52087990", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y17", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P00493-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "P00493-1.2.2", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P00493-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P00493-1.29.29", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P00493-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "P00493-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "P00493-1.34.34", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.184.184", "start_pos": 184, "end_pos": 184, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389516532", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389516532", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "LVKRTSRSVGYRPDFVGFEI", "down_seq": "DKFVVGYALDYNEYFRDLNH", "snv": [ { "evidence": [ { "id": "rs3389516532", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389516532" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109217", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P184", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P00493-1.166.166", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P00493-1.171.171", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P00493-1.174.174", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P00493-1.187.187", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.187.187", "start_pos": 187, "end_pos": 187, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389516525", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389516525", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "RTSRSVGYRPDFVGFEIPDK", "down_seq": "VVGYALDYNEYFRDLNHVCV", "snv": [ { "evidence": [ { "id": "rs3389516525", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389516525" } ], "glycoeffect": [], "sequence_org": "F", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109227", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "F187", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P00493-1.171.171", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "P00493-1.174.174", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P00493-1.184.184", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P00493-1.207.207", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.203.203", "start_pos": 203, "end_pos": 203, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389508401", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389508401", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IPDKFVVGYALDYNEYFRDL", "down_seq": "HVCVISETGKAKYKA", "snv": [ { "evidence": [ { "id": "rs3389508401", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389508401" } ], "glycoeffect": [], "sequence_org": "N", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109275", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N203", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P00493-1.184.184", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "downstream", "id": "P00493-1.187.187", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P00493-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P00493-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P00493-1.209.209", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P00493-1.210.210", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "upstream", "id": "P00493-1.215.215", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.207.207", "start_pos": 207, "end_pos": 207, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3410122330", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3410122330", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "V", "start_aa": "V", "up_seq": "FVVGYALDYNEYFRDLNHVC", "down_seq": "ISETGKAKYKA", "snv": [ { "evidence": [ { "id": "rs3410122330", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3410122330" } ], "glycoeffect": [], "sequence_org": "V", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109953", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "V207", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P00493-1.187.187", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P00493-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P00493-1.209.209", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P00493-1.210.210", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P00493-1.215.215", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.208.208", "start_pos": 208, "end_pos": 208, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3410226273", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3410226273", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "VVGYALDYNEYFRDLNHVCV", "down_seq": "SETGKAKYKA", "snv": [ { "evidence": [ { "id": "rs3410226273", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3410226273" } ], "glycoeffect": [], "sequence_org": "I", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109957", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I208", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P00493-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P00493-1.209.209", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P00493-1.210.210", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P00493-1.215.215", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.209.209", "start_pos": 209, "end_pos": 209, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3408043213", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3408043213", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VGYALDYNEYFRDLNHVCVI", "down_seq": "ETGKAKYKA", "snv": [ { "evidence": [ { "id": "rs3408043213", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3408043213" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109960", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S209", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P00493-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P00493-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P00493-1.210.210", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P00493-1.215.215", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.210.210", "start_pos": 210, "end_pos": 210, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3408043206", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3408043206", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "GYALDYNEYFRDLNHVCVIS", "down_seq": "TGKAKYKA", "snv": [ { "evidence": [ { "id": "rs3408043206", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3408043206" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "D", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109964", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E210", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P00493-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P00493-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P00493-1.209.209", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P00493-1.215.215", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.215.215", "start_pos": 215, "end_pos": 215, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389516546", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389516546", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "YNEYFRDLNHVCVISETGKA", "down_seq": "YKA", "snv": [ { "evidence": [ { "id": "rs3389516546", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389516546" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52109978", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K215", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P00493-1.203.203", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P00493-1.207.207", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P00493-1.208.208", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P00493-1.209.209", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P00493-1.210.210", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389553451", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389553451", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "RSPSVVISDDEPGYDLDLFC", "down_seq": "PNHYAEDLEKVFIPHGLIMD", "snv": [ { "evidence": [ { "id": "rs3389553451", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389553451" } ], "glycoeffect": [], "sequence_org": "I", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52088011", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I24", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P00493-1.29.29", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P00493-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P00493-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P00493-1.34.34", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.29.29", "start_pos": 29, "end_pos": 29, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs250007055", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs250007055", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "VISDDEPGYDLDLFCIPNHY", "down_seq": "EDLEKVFIPHGLIMDRTERL", "snv": [ { "evidence": [ { "id": "rs250007055", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs250007055" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52088026", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A29", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P00493-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P00493-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P00493-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P00493-1.34.34", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs30422582", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30422582", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "M", "down_seq": "TRSPSVVISDDEPGYDLDLF", "snv": [ { "evidence": [ { "id": "rs30422582", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30422582" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52077104", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P2", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P00493-1.0.0", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.30.30", "start_pos": 30, "end_pos": 30, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389558823", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389558823", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "ISDDEPGYDLDLFCIPNHYA", "down_seq": "DLEKVFIPHGLIMDRTERLA", "snv": [ { "evidence": [ { "id": "rs3389558823", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389558823" } ], "glycoeffect": [], "sequence_org": "E", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52088028", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "E30", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P00493-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P00493-1.29.29", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P00493-1.31.31", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P00493-1.34.34", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.31.31", "start_pos": 31, "end_pos": 31, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389575155", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389575155", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "SDDEPGYDLDLFCIPNHYAE", "down_seq": "LEKVFIPHGLIMDRTERLAR", "snv": [ { "evidence": [ { "id": "rs3389575155", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389575155" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52088032", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D31", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P00493-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P00493-1.29.29", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P00493-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P00493-1.34.34", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.34.34", "start_pos": 34, "end_pos": 34, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389575169", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389575169", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "EPGYDLDLFCIPNHYAEDLE", "down_seq": "VFIPHGLIMDRTERLARDVM", "snv": [ { "evidence": [ { "id": "rs3389575169", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389575169" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52088040", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K34", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P00493-1.17.17", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "P00493-1.24.24", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "P00493-1.29.29", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P00493-1.30.30", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P00493-1.31.31", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.68.68", "start_pos": 68, "end_pos": 68, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3410374422", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3410374422", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "RLARDVMKEMGGHHIVALCV", "down_seq": "KGGYKFFADLLDYIKALNRN", "snv": [ { "evidence": [ { "id": "rs3410374422", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3410374422" } ], "glycoeffect": [], "sequence_org": "L", "sequence_mut": "P", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, housekeeping gene.", "chr_id": "X", "chr_pos": "52091033", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "L68", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P00493-1.142.142", "start_pos": 142, "end_pos": 142, "uniprot_canonical_ac": "P00493-1", "length": 218, "uniprot_id": "HPRT_MOUSE", "protein_name": "Hypoxanthine-guanine phosphoribosyltransferase", "refseq_ac": "NP_038584", "refseq_name": "hypoxanthine-guanine phosphoribosyltransferase", "gene_name": "Hprt1", "gene_names_uniprotkb": "Hprt1; Hprt", "gene_names_refseq": "HPGRT; Hprt1; Hprt", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LSTLTGKNVLIVEDIIDTGK", "down_seq": "MQTLLSLVKQYSPKMVKVAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P00493", "url": "https://www.uniprot.org/uniprotkb/P00493" } ], "site_lbl": "Thr142" } ], "all_sites": [ { "type": "snv", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "166", "end_pos": "166" }, { "start_pos": "171", "end_pos": "171" }, { "start_pos": "174", "end_pos": "174" }, { "start_pos": "17", "end_pos": "17" }, { "start_pos": "184", "end_pos": "184" }, { "start_pos": "187", "end_pos": "187" }, { "start_pos": "203", "end_pos": "203" }, { "start_pos": "207", "end_pos": "207" }, { "start_pos": "208", "end_pos": "208" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "210", "end_pos": "210" }, { "start_pos": "215", "end_pos": "215" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "29", "end_pos": "29" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "30", "end_pos": "30" }, { "start_pos": "31", "end_pos": "31" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "68", "end_pos": "68" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "142", "end_pos": "142" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P00493-1.125.125", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.179.179", "start_pos": 179, "end_pos": 179, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VAASNTGGGLLYSRESAPPP", "down_seq": "APFNLADINDVSPSGGFVAE", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.231.231", "start_pos": 231, "end_pos": 231, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "database": "O-GlcNAc Atlas", "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.", "journal": "Cell stem cell", "date": "2012", "authors": "Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532" } ] }, { "title": "Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II.", "journal": "Genome biology", "date": "2025-03-24", "authors": "Rucli Sofia, Descostes Nicolas, Ermakova Yulia, Chitnavis Urvashi, Couturier Jeanne, Boskovic Ana, Boulard Matthieu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPQQPQPPGGGLMGKFVLKA", "down_seq": "LTTPGSEYSSPSVISVSKGS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser231", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q60793", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "id": "22608532", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22608532" }, { "id": "40128797", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40128797" }, { "id": "Q60793", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q60793" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q60793-1.213.213", "categories": [ "snv_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q60793-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q60793-1.251.251", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.233.233", "start_pos": 233, "end_pos": 233, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "database": "O-GlcNAc Atlas", "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.", "journal": "Cell stem cell", "date": "2012", "authors": "Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532" } ] }, { "title": "Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II.", "journal": "Genome biology", "date": "2025-03-24", "authors": "Rucli Sofia, Descostes Nicolas, Ermakova Yulia, Chitnavis Urvashi, Couturier Jeanne, Boskovic Ana, Boulard Matthieu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QQPQPPGGGLMGKFVLKASL", "down_seq": "TPGSEYSSPSVISVSKGSPD", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr233", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q60793", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "id": "22608532", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22608532" }, { "id": "40128797", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40128797" }, { "id": "Q60793", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q60793" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q60793-1.213.213", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q60793-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q60793-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q60793-1.253.253", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.237.237", "start_pos": 237, "end_pos": 237, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "database": "O-GlcNAc Atlas", "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.", "journal": "Cell stem cell", "date": "2012", "authors": "Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532" } ] }, { "title": "Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II.", "journal": "Genome biology", "date": "2025-03-24", "authors": "Rucli Sofia, Descostes Nicolas, Ermakova Yulia, Chitnavis Urvashi, Couturier Jeanne, Boskovic Ana, Boulard Matthieu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPGGGLMGKFVLKASLTTPG", "down_seq": "EYSSPSVISVSKGSPDGSHP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser237", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q60793", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "id": "22608532", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22608532" }, { "id": "40128797", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40128797" }, { "id": "Q60793", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q60793" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q60793-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q60793-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q60793-1.253.253", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "database": "O-GlcNAc Atlas", "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.", "journal": "Cell stem cell", "date": "2012", "authors": "Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532" } ] }, { "title": "Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II.", "journal": "Genome biology", "date": "2025-03-24", "authors": "Rucli Sofia, Descostes Nicolas, Ermakova Yulia, Chitnavis Urvashi, Couturier Jeanne, Boskovic Ana, Boulard Matthieu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LKASLTTPGSEYSSPSVISV", "down_seq": "KGSPDGSHPVVVAPYSGGPP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser248", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q60793", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "id": "22608532", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22608532" }, { "id": "40128797", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40128797" }, { "id": "Q60793", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q60793" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 17, "direction": "downstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q60793-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q60793-1.253.253", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.283.283", "start_pos": 283, "end_pos": 283, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "database": "O-GlcNAc Atlas", "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.", "journal": "Cell stem cell", "date": "2012", "authors": "Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532" } ] }, { "title": "Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II.", "journal": "Genome biology", "date": "2025-03-24", "authors": "Rucli Sofia, Descostes Nicolas, Ermakova Yulia, Chitnavis Urvashi, Couturier Jeanne, Boskovic Ana, Boulard Matthieu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YSGGPPRMCPKIKQEAVPSC", "down_seq": "VSRSLEAHLSAGPQLSNGHR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q60793", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "id": "22608532", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22608532" }, { "id": "40128797", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40128797" }, { "id": "Q60793", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q60793" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q60793-1.274.274", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q60793-1.285.285", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q60793-1.296.296", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.285.285", "start_pos": 285, "end_pos": 285, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "database": "O-GlcNAc Atlas", "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.", "journal": "Cell stem cell", "date": "2012", "authors": "Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532" } ] }, { "title": "Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II.", "journal": "Genome biology", "date": "2025-03-24", "authors": "Rucli Sofia, Descostes Nicolas, Ermakova Yulia, Chitnavis Urvashi, Couturier Jeanne, Boskovic Ana, Boulard Matthieu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" } ], "reference": [ { "type": "PubMed", "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797" } ] } ], "crossref": [ { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "22608532", "url": "https://glygen.org/publication/PubMed/22608532", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40128797", "url": "https://glygen.org/publication/PubMed/40128797", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q60793", "url": "https://oglcnac.org/atlas/detail/Q60793", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "rs3388683255", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388683255", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GGPPRMCPKIKQEAVPSCTV", "down_seq": "RSLEAHLSAGPQLSNGHRPN", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser285", "evidence": [ { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "Q60793", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q60793" }, { "id": "22608532", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22608532" }, { "id": "40128797", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40128797" }, { "id": "Q60793", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q60793" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388683255", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388683255" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "I", "comment": "Germline mutation passed 2 filters: o-glyco-site-loss (S->I); glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530256", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S285", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q60793-1.274.274", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q60793-1.283.283", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q60793-1.296.296", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.229.229", "start_pos": 229, "end_pos": 229, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.", "journal": "Nature communications", "date": "2018", "authors": "Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "reference": [ { "type": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "crossref": [ { "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "YIPPQQPQPPGGGLMGKFVL", "down_seq": "ASLTTPGSEYSSPSVISVSK", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "R", "comment": "Increased cell reprogramming and pluripotency. No change in promoter-binding of target genes.", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" }, { "database": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q60793-1.213.213", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q60793-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.326.326", "start_pos": 326, "end_pos": 326, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.", "journal": "Nature communications", "date": "2018", "authors": "Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "reference": [ { "type": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "crossref": [ { "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "THDFPLGRQLPTRTTPTLSP", "down_seq": "ELLNSRDCHPGLPLPPGFHP", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No change in KLF4 polyglutamylation.", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" }, { "database": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q60793-1.309.309", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q60793-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.381.381", "start_pos": 381, "end_pos": 381, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.", "journal": "Nature communications", "date": "2018", "authors": "Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "reference": [ { "type": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "crossref": [ { "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "QSQVPSLHYQELMPPGSCLP", "down_seq": "EPKPKRGRRSWPRKRTATHT", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "Loss of polyglutamylation, reduced cell reprogramming and pluripotency maintenance. Forms heterodimer with KLF5. No change in promoter-binding of target genes. Embryo lethality in mutant homozygous mice.", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" }, { "database": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "Q60793-1.397.397", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q60793-1.399.399", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.46.46", "start_pos": 46, "end_pos": 46, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.", "journal": "Nature communications", "date": "2018", "authors": "Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "reference": [ { "type": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "crossref": [ { "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "GPAGREKTLRPAGAPTNRWR", "down_seq": "ELSHMKRLPPLPGRPYDLAA", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No change in KLF4 polyglutamylation.", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" }, { "database": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.", "journal": "Nature communications", "date": "2018", "authors": "Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "reference": [ { "type": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "crossref": [ { "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "E", "start_aa": "E", "up_seq": "GGAGAACSSNNPALLARRET", "down_seq": "EFNDLLDLDFILSNSLTHQE", "mutagenesis": [ { "sequence_org": "E", "sequence_mut": "A", "comment": "No change in KLF4 polyglutamylation.", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" }, { "database": "PubMed", "id": "29593216", "url": "https://glygen.org/publication/PubMed/29593216" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.141.141", "start_pos": 141, "end_pos": 141, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs5526529225", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5526529225", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "VTTSASASSSSSPASSGPAS", "down_seq": "PSTCSFSYPIRAGGDPGVAA", "snv": [ { "evidence": [ { "id": "rs5526529225", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5526529225" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "V", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530688", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A141", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.213.213", "start_pos": 213, "end_pos": 213, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3394306149", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394306149", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "SGGFVAELLRPELDPVYIPP", "down_seq": "QPQPPGGGLMGKFVLKASLT", "snv": [ { "evidence": [ { "id": "rs3394306149", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394306149" } ], "glycoeffect": [], "sequence_org": "Q", "sequence_mut": "H", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530471", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Q213", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "Q60793-1.219.219", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.219.219", "start_pos": 219, "end_pos": 219, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3394324424", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394324424", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "ELLRPELDPVYIPPQQPQPP", "down_seq": "GGLMGKFVLKASLTTPGSEY", "snv": [ { "evidence": [ { "id": "rs3394324424", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394324424" } ], "glycoeffect": [], "sequence_org": "G", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530454", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G219", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q60793-1.213.213", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.243.243", "start_pos": 243, "end_pos": 243, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs13460894", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs13460894", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MGKFVLKASLTTPGSEYSSP", "down_seq": "VISVSKGSPDGSHPVVVAPY", "snv": [ { "evidence": [ { "id": "rs13460894", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs13460894" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530382", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S243", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q60793-1.229.229", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q60793-1.251.251", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q60793-1.253.253", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.253.253", "start_pos": 253, "end_pos": 253, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs5526582418", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5526582418", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "TTPGSEYSSPSVISVSKGSP", "down_seq": "GSHPVVVAPYSGGPPRMCPK", "snv": [ { "evidence": [ { "id": "rs5526582418", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs5526582418" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "E", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530351", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D253", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "downstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q60793-1.251.251", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.274.274", "start_pos": 274, "end_pos": 274, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388689674", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388689674", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "GSHPVVVAPYSGGPPRMCPK", "down_seq": "KQEAVPSCTVSRSLEAHLSA", "snv": [ { "evidence": [ { "id": "rs3388689674", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388689674" } ], "glycoeffect": [], "sequence_org": "I", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530290", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I274", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q60793-1.283.283", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q60793-1.285.285", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.296.296", "start_pos": 296, "end_pos": 296, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388680384", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388680384", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "QEAVPSCTVSRSLEAHLSAG", "down_seq": "QLSNGHRPNTHDFPLGRQLP", "snv": [ { "evidence": [ { "id": "rs3388680384", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388680384" } ], "glycoeffect": [], "sequence_org": "P", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530223", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P296", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q60793-1.283.283", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q60793-1.285.285", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q60793-1.309.309", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q60793-1.313.313", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.309.309", "start_pos": 309, "end_pos": 309, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3394264293", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394264293", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "EAHLSAGPQLSNGHRPNTHD", "down_seq": "PLGRQLPTRTTPTLSPEELL", "snv": [ { "evidence": [ { "id": "rs3394264293", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394264293" } ], "glycoeffect": [], "sequence_org": "F", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530184", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "F309", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q60793-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q60793-1.313.313", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q60793-1.326.326", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.313.313", "start_pos": 313, "end_pos": 313, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3394125938", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394125938", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "SAGPQLSNGHRPNTHDFPLG", "down_seq": "QLPTRTTPTLSPEELLNSRD", "snv": [ { "evidence": [ { "id": "rs3394125938", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3394125938" } ], "glycoeffect": [], "sequence_org": "R", "sequence_mut": "Q", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530172", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R313", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q60793-1.296.296", "categories": [ "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q60793-1.309.309", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q60793-1.326.326", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.352.352", "start_pos": 352, "end_pos": 352, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388685161", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388685161", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RDCHPGLPLPPGFHPHPGPN", "down_seq": "PPFLPDQMQSQVPSLHYQEL", "snv": [ { "evidence": [ { "id": "rs3388685161", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388685161" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55530055", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y352", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.407.407", "start_pos": 407, "end_pos": 407, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388689656", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388689656", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "RGRRSWPRKRTATHTCDYAG", "down_seq": "GKTYTKSSHLKAHLRTHTGE", "snv": [ { "evidence": [ { "id": "rs3388689656", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388689656" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55529774", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C407", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "Q60793-1.397.397", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q60793-1.399.399", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q60793-1.413.413", "categories": [ "snv_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q60793-1.420.420", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q60793-1.423.423", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.413.413", "start_pos": 413, "end_pos": 413, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388672684", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388672684", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "PRKRTATHTCDYAGCGKTYT", "down_seq": "SSHLKAHLRTHTGEKPYHCD", "snv": [ { "evidence": [ { "id": "rs3388672684", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388672684" } ], "glycoeffect": [], "sequence_org": "K", "sequence_mut": "M", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55529756", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K413", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q60793-1.397.397", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q60793-1.399.399", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q60793-1.407.407", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q60793-1.420.420", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q60793-1.423.423", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.420.420", "start_pos": 420, "end_pos": 420, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388683328", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388683328", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "HTCDYAGCGKTYTKSSHLKA", "down_seq": "LRTHTGEKPYHCDWDGCGWK", "snv": [ { "evidence": [ { "id": "rs3388683328", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388683328" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55529736", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H420", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q60793-1.407.407", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q60793-1.413.413", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q60793-1.423.423", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.423.423", "start_pos": 423, "end_pos": 423, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388686818", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388686818", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DYAGCGKTYTKSSHLKAHLR", "down_seq": "HTGEKPYHCDWDGCGWKFAR", "snv": [ { "evidence": [ { "id": "rs3388686818", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388686818" } ], "glycoeffect": [], "sequence_org": "T", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55529727", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T423", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q60793-1.407.407", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q60793-1.413.413", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q60793-1.420.420", "categories": [ "snv_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q60793-1.442.442", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.442.442", "start_pos": 442, "end_pos": 442, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542374158", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542374158", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "RTHTGEKPYHCDWDGCGWKF", "down_seq": "RSDELTRHYRKHTGHRPFQC", "snv": [ { "evidence": [ { "id": "rs3542374158", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542374158" } ], "glycoeffect": [], "sequence_org": "A", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528253", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "A442", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "Q60793-1.423.423", "categories": [ "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q60793-1.444.444", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q60793-1.445.445", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.444.444", "start_pos": 444, "end_pos": 444, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542339905", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542339905", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HTGEKPYHCDWDGCGWKFAR", "down_seq": "DELTRHYRKHTGHRPFQCQK", "snv": [ { "evidence": [ { "id": "rs3542339905", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542339905" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "A", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528247", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S444", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q60793-1.442.442", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q60793-1.445.445", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.445.445", "start_pos": 445, "end_pos": 445, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542260339", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542260339", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "TGEKPYHCDWDGCGWKFARS", "down_seq": "ELTRHYRKHTGHRPFQCQKC", "snv": [ { "evidence": [ { "id": "rs3542260339", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542260339" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528244", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D445", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q60793-1.442.442", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q60793-1.444.444", "categories": [ "snv_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q60793-1.465.465", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.465.465", "start_pos": 465, "end_pos": 465, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388684352", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388684352", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "DELTRHYRKHTGHRPFQCQK", "down_seq": "DRAFSRSDHLALHMKRHF", "snv": [ { "evidence": [ { "id": "rs3388684352", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388684352" } ], "glycoeffect": [], "sequence_org": "C", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528183", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "C465", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q60793-1.445.445", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q60793-1.472.472", "categories": [ "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q60793-1.473.473", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q60793-1.479.479", "categories": [ "snv_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q60793-1.482.482", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.472.472", "start_pos": 472, "end_pos": 472, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542259168", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542259168", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKHTGHRPFQCQKCDRAFSR", "down_seq": "DHLALHMKRHF", "snv": [ { "evidence": [ { "id": "rs3542259168", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542259168" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "W", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528162", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S472", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q60793-1.465.465", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q60793-1.473.473", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q60793-1.479.479", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q60793-1.482.482", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.473.473", "start_pos": 473, "end_pos": 473, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542268679", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542268679", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "D", "start_aa": "D", "up_seq": "KHTGHRPFQCQKCDRAFSRS", "down_seq": "HLALHMKRHF", "snv": [ { "evidence": [ { "id": "rs3542268679", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542268679" } ], "glycoeffect": [], "sequence_org": "D", "sequence_mut": "G", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528159", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "D473", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q60793-1.465.465", "categories": [ "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q60793-1.472.472", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q60793-1.479.479", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q60793-1.482.482", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.479.479", "start_pos": 479, "end_pos": 479, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542289474", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542289474", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "M", "start_aa": "M", "up_seq": "PFQCQKCDRAFSRSDHLALH", "down_seq": "KRHF", "snv": [ { "evidence": [ { "id": "rs3542289474", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542289474" } ], "glycoeffect": [], "sequence_org": "M", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528140", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "M479", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q60793-1.465.465", "categories": [ "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q60793-1.472.472", "categories": [ "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q60793-1.473.473", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q60793-1.482.482", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.482.482", "start_pos": 482, "end_pos": 482, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3542267334", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542267334", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "CQKCDRAFSRSDHLALHMKR", "down_seq": "", "snv": [ { "evidence": [ { "id": "rs3542267334", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3542267334" } ], "glycoeffect": [], "sequence_org": "H", "sequence_mut": "L", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, stem cell markers.", "chr_id": "4", "chr_pos": "55528132", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H482", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q60793-1.465.465", "categories": [ "snv_flag" ] }, { "distance": 10, "direction": "downstream", "id": "Q60793-1.472.472", "categories": [ "snv_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q60793-1.473.473", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q60793-1.479.479", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.251.251", "start_pos": 251, "end_pos": 251, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SLTTPGSEYSSPSVISVSKG", "down_seq": "PDGSHPVVVAPYSGGPPRMC", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "site_lbl": "Ser251" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q60793-1.231.231", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "downstream", "id": "Q60793-1.233.233", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "Q60793-1.237.237", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q60793-1.243.243", "categories": [ "snv_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q60793-1.248.248", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q60793-1.253.253", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q60793-1.397.397", "start_pos": 397, "end_pos": 397, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Akt-signal integration is involved in the differentiation of embryonal carcinoma cells.", "journal": "PloS one", "date": "2013", "authors": "Chen B, Xue Z, Yang G, Shi B, Yang B, Yan Y, Wang X, Han D, Huang Y, Dong W", "evidence": [ { "database": "iPTMnet", "id": "Q60793", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q60793" } ], "reference": [ { "type": "PubMed", "id": "23762260", "url": "https://glygen.org/publication/PubMed/23762260" } ] } ], "crossref": [ { "id": "Q60793", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q60793", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23762260", "url": "https://glygen.org/publication/PubMed/23762260", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SCLPEEPKPKRGRRSWPRKR", "down_seq": "ATHTCDYAGCGKTYTKSSHL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q60793", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q60793" }, { "database": "PubMed", "id": "23762260", "url": "https://glygen.org/publication/PubMed/23762260" } ], "site_lbl": "Thr397" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q60793-1.381.381", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q60793-1.399.399", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "Q60793-1.407.407", "categories": [ "snv_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q60793-1.413.413", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q60793-1.399.399", "start_pos": 399, "end_pos": 399, "uniprot_canonical_ac": "Q60793-1", "length": 483, "uniprot_id": "KLF4_MOUSE", "protein_name": "Krueppel-like factor 4", "refseq_ac": "NP_034767", "refseq_name": "Krueppel-like factor 4", "gene_name": "Klf4", "gene_names_uniprotkb": "Klf4; Ezf; Gklf; Zie", "gene_names_refseq": "EZF; Gklf; Klf4; Zie", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60793", "url": "https://www.uniprot.org/uniprotkb/Q60793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Akt-signal integration is involved in the differentiation of embryonal carcinoma cells.", "journal": "PloS one", "date": "2013", "authors": "Chen B, Xue Z, Yang G, Shi B, Yang B, Yan Y, Wang X, Han D, Huang Y, Dong W", "evidence": [ { "database": "iPTMnet", "id": "Q60793", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q60793" } ], "reference": [ { "type": "PubMed", "id": "23762260", "url": "https://glygen.org/publication/PubMed/23762260" } ] } ], "crossref": [ { "id": "Q60793", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q60793", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "23762260", "url": "https://glygen.org/publication/PubMed/23762260", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LPEEPKPKRGRRSWPRKRTA", "down_seq": "HTCDYAGCGKTYTKSSHLKA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q60793", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q60793" }, { "database": "PubMed", "id": "23762260", "url": "https://glygen.org/publication/PubMed/23762260" } ], "site_lbl": "Thr399" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "179", "end_pos": "179" }, { "start_pos": "231", "end_pos": "231" }, { "start_pos": "233", "end_pos": "233" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "283", "end_pos": "283" }, { "start_pos": "285", "end_pos": "285" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "229", "end_pos": "229" }, { "start_pos": "326", "end_pos": "326" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "46", "end_pos": "46" }, { "start_pos": "95", "end_pos": "95" } ] }, { "type": "snv", "site_list": [ { "start_pos": "285", "end_pos": "285" }, { "start_pos": "141", "end_pos": "141" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "219", "end_pos": "219" }, { "start_pos": "243", "end_pos": "243" }, { "start_pos": "253", "end_pos": "253" }, { "start_pos": "274", "end_pos": "274" }, { "start_pos": "296", "end_pos": "296" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "313", "end_pos": "313" }, { "start_pos": "352", "end_pos": "352" }, { "start_pos": "407", "end_pos": "407" }, { "start_pos": "413", "end_pos": "413" }, { "start_pos": "420", "end_pos": "420" }, { "start_pos": "423", "end_pos": "423" }, { "start_pos": "442", "end_pos": "442" }, { "start_pos": "444", "end_pos": "444" }, { "start_pos": "445", "end_pos": "445" }, { "start_pos": "465", "end_pos": "465" }, { "start_pos": "472", "end_pos": "472" }, { "start_pos": "473", "end_pos": "473" }, { "start_pos": "479", "end_pos": "479" }, { "start_pos": "482", "end_pos": "482" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "251", "end_pos": "251" }, { "start_pos": "397", "end_pos": "397" }, { "start_pos": "399", "end_pos": "399" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q60793-1.381.381", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q60793-1.397.397", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q60793-1.407.407", "categories": [ "snv_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q60793-1.413.413", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.193.193", "start_pos": 193, "end_pos": 193, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Point mutations in the WD40 domain of Eed block its interaction with Ezh2.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Denisenko O, Shnyreva M, Suzuki H, Bomsztyk K", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "9742080", "url": "https://glygen.org/publication/PubMed/9742080" } ] }, { "title": "The product of the murine homolog of the Drosophila extra sex combs gene displays transcriptional repressor activity.", "journal": "Molecular and cellular biology", "date": "1997", "authors": "Denisenko ON, Bomsztyk K", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "9234727", "url": "https://glygen.org/publication/PubMed/9234727" } ] } ], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "9742080", "url": "https://glygen.org/publication/PubMed/9742080", "database": "PubMed", "categories": [ "Other" ] }, { "id": "9234727", "url": "https://glygen.org/publication/PubMed/9234727", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "RIINPITMQCIKHYVGHGNA", "down_seq": "NELKFHPRDPNLLLSVSKDH", "mutagenesis": [ { "sequence_org": "I", "sequence_mut": "N", "comment": "Hypomorphic allele. Abrogates interaction with EZH2 and impairs transcriptional repression.", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "PubMed", "id": "9742080", "url": "https://glygen.org/publication/PubMed/9742080" }, { "database": "PubMed", "id": "9234727", "url": "https://glygen.org/publication/PubMed/9234727" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q921E6-1.196.196", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Developmental regulation of Eed complex composition governs a switch in global histone modification in brain.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Kim SY, Levenson JM, Korsmeyer S, Sweatt JD, Schumacher A", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "17259173", "url": "https://glygen.org/publication/PubMed/17259173" } ] }, { "title": "Point mutations in the WD40 domain of Eed block its interaction with Ezh2.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Denisenko O, Shnyreva M, Suzuki H, Bomsztyk K", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "9742080", "url": "https://glygen.org/publication/PubMed/9742080" } ] }, { "title": "The product of the murine homolog of the Drosophila extra sex combs gene displays transcriptional repressor activity.", "journal": "Molecular and cellular biology", "date": "1997", "authors": "Denisenko ON, Bomsztyk K", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "9234727", "url": "https://glygen.org/publication/PubMed/9234727" } ] } ], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17259173", "url": "https://glygen.org/publication/PubMed/17259173", "database": "PubMed", "categories": [ "Other" ] }, { "id": "9742080", "url": "https://glygen.org/publication/PubMed/9742080", "database": "PubMed", "categories": [ "Other" ] }, { "id": "9234727", "url": "https://glygen.org/publication/PubMed/9234727", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "NPITMQCIKHYVGHGNAINE", "down_seq": "KFHPRDPNLLLSVSKDHALR", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "P", "comment": "Null allele. Abrogates interaction with EZH2 and impairs transcriptional repression.", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "PubMed", "id": "17259173", "url": "https://glygen.org/publication/PubMed/17259173" }, { "database": "PubMed", "id": "9742080", "url": "https://glygen.org/publication/PubMed/9742080" }, { "database": "PubMed", "id": "9234727", "url": "https://glygen.org/publication/PubMed/9234727" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q921E6-1.193.193", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.246.246", "start_pos": 246, "end_pos": 246, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis of EZH2 recognition by EED.", "journal": "Structure (London, England : 1993)", "date": "2007", "authors": "Han Z, Xing X, Hu M, Zhang Y, Liu P, Chai J", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919" } ] } ], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "VAIFGGVEGHRDEVLSADYD", "down_seq": "LGEKIMSCGMDHSLKLWRIN", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "E", "comment": "Abrogates interaction with EZH2.", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "PubMed", "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.315.315", "start_pos": 315, "end_pos": 315, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis of EZH2 recognition by EED.", "journal": "Structure (London, England : 1993)", "date": "2007", "authors": "Han Z, Xing X, Hu M, Zhang Y, Liu P, Chai J", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919" } ] } ], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "HFPDFSTRDIHRNYVDCVRW", "down_seq": "GDLILSKSCENAIVCWKPGK", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "E", "comment": "Impairs interaction with EZH2.", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "PubMed", "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q921E6-1.316.316", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.316.316", "start_pos": 316, "end_pos": 316, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Structural basis of EZH2 recognition by EED.", "journal": "Structure (London, England : 1993)", "date": "2007", "authors": "Han Z, Xing X, Hu M, Zhang Y, Liu P, Chai J", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919" } ] } ], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "FPDFSTRDIHRNYVDCVRWL", "down_seq": "DLILSKSCENAIVCWKPGKM", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "A", "comment": "Impairs interaction with EZH2.", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "PubMed", "id": "17937919", "url": "https://glygen.org/publication/PubMed/17937919" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q921E6-1.315.315", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "EREVSTAPAGTDMPAAKKQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q921E6-1.34.34", "start_pos": 34, "end_pos": 34, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "iPTMnet", "id": "Q921E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q921E6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q921E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q921E6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DMPAAKKQKLSSDENSNPDL", "down_seq": "GDENDDAVSIESGTNTERPD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q921E6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q921E6" } ], "site_lbl": "Ser34" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q921E6-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "Q921E6-1", "length": 441, "uniprot_id": "EED_MOUSE", "protein_name": "Polycomb protein EED", "refseq_ac": "NP_068676", "refseq_name": "polycomb protein EED", "gene_name": "Eed", "gene_names_uniprotkb": "Eed", "gene_names_refseq": "Eed; l(7)5Rn; l7Rn5; lusk", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GDENDDAVSIESGTNTERPD", "down_seq": "PTNTPNAPGRKSWGKGKWKS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q921E6", "url": "https://www.uniprot.org/uniprotkb/Q921E6" } ], "site_lbl": "Thr55" } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "193", "end_pos": "193" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "246", "end_pos": "246" }, { "start_pos": "315", "end_pos": "315" }, { "start_pos": "316", "end_pos": "316" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "2", "end_pos": "2" }, { "start_pos": "34", "end_pos": "34" }, { "start_pos": "55", "end_pos": "55" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q9U8-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "E9Q9U8-1", "length": 364, "uniprot_id": "E9Q9U8_MOUSE", "protein_name": "Coiled-coil domain containing 74A", "refseq_ac": "NP_001159636", "refseq_name": "coiled-coil domain-containing protein 74B isoform 1", "gene_name": "Ccdc74a", "gene_names_uniprotkb": "Ccdc74a", "gene_names_refseq": "2310015A05Rik; Ccdc74a", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q9U8", "url": "https://www.uniprot.org/uniprotkb/E9Q9U8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KPQKKGSISTWSLHSGKSAS", "down_seq": "STMSANSQGKTRPQPSSFKK", "glycosylation": [ { "glytoucan_ac": "G59324HL", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SASNSTMSANSQGK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn117", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2ATK9-1.194.194", "start_pos": 194, "end_pos": 194, "uniprot_canonical_ac": "A2ATK9-1", "length": 892, "uniprot_id": "A2ATK9_MOUSE", "protein_name": "Family with sequence similarity 171, member A1", "refseq_ac": "NP_001074630", "refseq_name": "protein FAM171A1 isoform 1", "gene_name": "Fam171a1", "gene_names_uniprotkb": "Fam171a1", "gene_names_refseq": "9630050M13Rik; Fam171a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2ATK9", "url": "https://www.uniprot.org/uniprotkb/A2ATK9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SPSEVDSFPYLRGLDGNGTG", "down_seq": "STRYDLTPVTAVSVHLLSGN", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GLDGNGTGNSTR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn194", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "194", "end_pos": "194" }, { "start_pos": "380", "end_pos": "380" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2ATK9-1.380.380", "start_pos": 380, "end_pos": 380, "uniprot_canonical_ac": "A2ATK9-1", "length": 892, "uniprot_id": "A2ATK9_MOUSE", "protein_name": "Family with sequence similarity 171, member A1", "refseq_ac": "NP_001074630", "refseq_name": "protein FAM171A1 isoform 1", "gene_name": "Fam171a1", "gene_names_uniprotkb": "Fam171a1", "gene_names_refseq": "9630050M13Rik; Fam171a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2ATK9", "url": "https://www.uniprot.org/uniprotkb/A2ATK9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2ATK9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2ATK9" }, { "database": "O-GlcNAc Atlas", "id": "A2ATK9", "url": "https://oglcnac.org/atlas/detail/A2ATK9" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2ATK9", "url": "https://oglcnac.org/atlas/detail/A2ATK9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SHINLLFSRRASDYPGPLSV", "down_seq": "SHSRPEAPGTKELMGGVHLE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser380", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "A2ATK9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2ATK9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "194", "end_pos": "194" }, { "start_pos": "380", "end_pos": "380" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "A2ATK9-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "A2ATK9-1", "length": 892, "uniprot_id": "A2ATK9_MOUSE", "protein_name": "Family with sequence similarity 171, member A1", "refseq_ac": "NP_001074630", "refseq_name": "protein FAM171A1 isoform 1", "gene_name": "Fam171a1", "gene_names_uniprotkb": "Fam171a1", "gene_names_refseq": "9630050M13Rik; Fam171a1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2ATK9", "url": "https://www.uniprot.org/uniprotkb/A2ATK9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2ATK9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2ATK9" }, { "database": "O-GlcNAc Atlas", "id": "A2ATK9", "url": "https://oglcnac.org/atlas/detail/A2ATK9" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "A2ATK9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2ATK9", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "A2ATK9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2ATK9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "194", "end_pos": "194" }, { "start_pos": "380", "end_pos": "380" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CDU6-1.9.9", "start_pos": 9, "end_pos": 9, "uniprot_canonical_ac": "Q8CDU6-1", "length": 774, "uniprot_id": "HECD2_MOUSE", "protein_name": "Probable E3 ubiquitin-protein ligase HECTD2", "refseq_ac": "NP_001156943", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD2 isoform 1", "gene_name": "Hectd2", "gene_names_uniprotkb": "Hectd2", "gene_names_refseq": "4921524L07; A630025O09Rik; Hectd2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CDU6", "url": "https://www.uniprot.org/uniprotkb/Q8CDU6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8CDU6", "url": "https://www.uniprot.org/uniprotkb/Q8CDU6" }, { "database": "iPTMnet", "id": "Q8CDU6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CDU6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8CDU6", "url": "https://www.uniprot.org/uniprotkb/Q8CDU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8CDU6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CDU6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MSEAARDL", "down_seq": "PGAPPAVAAAAPEERKGKEP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CDU6", "url": "https://www.uniprot.org/uniprotkb/Q8CDU6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8CDU6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CDU6" } ], "site_lbl": "Ser9" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "9", "end_pos": "9" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q5M6-1.1069.1069", "start_pos": 1069, "end_pos": 1069, "uniprot_canonical_ac": "E9Q5M6-1", "length": 1843, "uniprot_id": "CFA44_MOUSE", "protein_name": "Cilia- and flagella-associated protein 44", "refseq_ac": "NP_001028419", "refseq_name": "cilia- and flagella-associated protein 44", "gene_name": "Cfap44", "gene_names_uniprotkb": "Cfap44", "gene_names_refseq": "6330444M21Rik; Cfap44; D16Ertd642e; Gm1750; Wdr52", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q5M6", "url": "https://www.uniprot.org/uniprotkb/E9Q5M6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "E9Q5M6", "url": "https://www.uniprot.org/uniprotkb/E9Q5M6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SERRQSKMERLEKEGPGKKE", "down_seq": "QRDTGGSISLQEESVLEKGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "E9Q5M6", "url": "https://www.uniprot.org/uniprotkb/E9Q5M6" } ], "site_lbl": "Ser1069" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "1069", "end_pos": "1069" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PASTPKRVPMGPIIVPPGGH", "down_seq": "VPSTPPVVTIAPTKTVNGVW", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser116", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q3U3C9-1.119.119", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q3U3C9-1.125.125", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.119.119", "start_pos": 119, "end_pos": 119, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TPKRVPMGPIIVPPGGHSVP", "down_seq": "TPPVVTIAPTKTVNGVWRSE", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser119", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q3U3C9-1.116.116", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q3U3C9-1.125.125", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.125.125", "start_pos": 125, "end_pos": 125, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "MGPIIVPPGGHSVPSTPPVV", "down_seq": "IAPTKTVNGVWRSESRQDSG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q3U3C9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q3U3C9-1.116.116", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q3U3C9-1.119.119", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.212.212", "start_pos": 212, "end_pos": 212, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QDSRFQPLNLQRPVHHVVPP", "down_seq": "TVTEDYLRSFRPYHTAEDLR", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser212", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q3U3C9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q3U3C9-1.213.213", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.213.213", "start_pos": 213, "end_pos": 213, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DSRFQPLNLQRPVHHVVPPS", "down_seq": "VTEDYLRSFRPYHTAEDLRM", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q3U3C9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q3U3C9-1.212.212", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.285.285", "start_pos": 285, "end_pos": 285, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FRMDDSYCLSALRSPFYPIP", "down_seq": "PGSLPPLHPSAMHLHLSGVR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr285", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.81.81", "start_pos": 81, "end_pos": 81, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAALRKLAKQAEEPRGSSLS", "down_seq": "ESSPVSSPATNHSSPASTPK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser81", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q3U3C9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q3U3C9-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q3U3C9-1.87.87", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q3U3C9-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.87.87", "start_pos": 87, "end_pos": 87, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker.", "journal": "ACS chemical biology", "date": "2018", "authors": "Qin K, Zhu Y, Qin W, Gao J, Shao X, Wang YL, Zhou W, Wang C, Chen X", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "database": "O-GlcNAc Atlas", "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "30059200", "url": "https://glygen.org/publication/PubMed/30059200", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34678516", "url": "https://glygen.org/publication/PubMed/34678516", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "https://oglcnac.org/atlas/detail/Q3U3C9", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LAKQAEEPRGSSLSSESSPV", "down_seq": "SPATNHSSPASTPKRVPMGP", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser87", "evidence": [ { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q3U3C9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3U3C9" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "34678516", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34678516" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "Q3U3C9", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q3U3C9" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q3U3C9-1.81.81", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q3U3C9-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q3U3C9-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.906.906", "start_pos": 906, "end_pos": 906, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3388991284", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388991284", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LVEMLRAMKQRALSAADSVT", "down_seq": "SSRDSPPVSLSEPATQPAPL", "glycosylation": [ { "glytoucan_ac": "G31852PQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ALSAADSVTNSSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn906", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388991284", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388991284" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "Y", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NSS->YSS).", "chr_id": "8", "chr_pos": "121300981", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N906", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "Q3U3C9-1.905.905", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q3U3C9-1.907.907", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.1099.1099", "start_pos": 1099, "end_pos": 1099, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GQQEPPMGRKGPPMQEADQD", "down_seq": "EEDSEEDSEEEAEEAPRRQW", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "site_lbl": "Ser1099" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.10.10", "start_pos": 10, "end_pos": 10, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MKGMSHEPK", "down_seq": "PSIGMLSTATRTTATVNPLT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Ser10" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.433.433", "start_pos": 433, "end_pos": 433, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ELHGLRGHSTEERPKPSEQL", "down_seq": "PTRAEKLKDVGLQAPKPVQH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Thr433" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.766.766", "start_pos": 766, "end_pos": 766, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RRREAQEKGYYYDLDDSYDE", "down_seq": "DEEEVRAHLRCVAEQPPLKL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "site_lbl": "Ser766" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.826.826", "start_pos": 826, "end_pos": 826, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QKEELVAQKRRKRRRMLRER", "down_seq": "PSPPAVQCKRQTPSPRLALS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Ser826" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q3U3C9-1.828.828", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.828.828", "start_pos": 828, "end_pos": 828, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EELVAQKRRKRRRMLRERSP", "down_seq": "PPAVQCKRQTPSPRLALSTR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Ser828" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q3U3C9-1.826.826", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.84.84", "start_pos": 84, "end_pos": 84, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LRKLAKQAEEPRGSSLSSES", "down_seq": "PVSSPATNHSSPASTPKRVP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "site_lbl": "Ser84" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q3U3C9-1.81.81", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q3U3C9-1.87.87", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q3U3C9-1.95.95", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3U3C9-1.857.857", "start_pos": 857, "end_pos": 857, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QTPSPRLALSTRYSPDEMNN", "down_seq": "PNFEEKRKFLTFFNLTHISA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Ser857" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.905.905", "start_pos": 905, "end_pos": 905, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RLVEMLRAMKQRALSAADSV", "down_seq": "NSSRDSPPVSLSEPATQPAP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Thr905" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "Q3U3C9-1.906.906", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q3U3C9-1.907.907", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.907.907", "start_pos": 907, "end_pos": 907, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VEMLRAMKQRALSAADSVTN", "down_seq": "SRDSPPVSLSEPATQPAPLE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "site_lbl": "Ser907" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q3U3C9-1.905.905", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q3U3C9-1.906.906", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q3U3C9-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "Q3U3C9-1", "length": 1213, "uniprot_id": "GSE1_MOUSE", "protein_name": "Genetic suppressor element 1", "refseq_ac": "NP_001139368", "refseq_name": "genetic suppressor element 1 isoform 2", "gene_name": "Gse1", "gene_names_uniprotkb": "Gse1; Kiaa0182", "gene_names_refseq": "2210013I18Rik; Gse1; mKIAA0182", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RGSSLSSESSPVSSPATNHS", "down_seq": "PASTPKRVPMGPIIVPPGGH", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q3U3C9", "url": "https://www.uniprot.org/uniprotkb/Q3U3C9" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q3U3C9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q3U3C9" } ], "site_lbl": "Ser95" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "119", "end_pos": "119" }, { "start_pos": "125", "end_pos": "125" }, { "start_pos": "212", "end_pos": "212" }, { "start_pos": "213", "end_pos": "213" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "81", "end_pos": "81" }, { "start_pos": "87", "end_pos": "87" }, { "start_pos": "906", "end_pos": "906" } ] }, { "type": "snv", "site_list": [ { "start_pos": "906", "end_pos": "906" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1099", "end_pos": "1099" }, { "start_pos": "10", "end_pos": "10" }, { "start_pos": "433", "end_pos": "433" }, { "start_pos": "766", "end_pos": "766" }, { "start_pos": "826", "end_pos": "826" }, { "start_pos": "828", "end_pos": "828" }, { "start_pos": "84", "end_pos": "84" }, { "start_pos": "857", "end_pos": "857" }, { "start_pos": "905", "end_pos": "905" }, { "start_pos": "907", "end_pos": "907" }, { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q3U3C9-1.81.81", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q3U3C9-1.84.84", "categories": [ "phosphorylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q3U3C9-1.87.87", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q3ULW8-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q3ULW8-1", "length": 533, "uniprot_id": "PARP3_MOUSE", "protein_name": "Protein mono-ADP-ribosyltransferase PARP3", "refseq_ac": "NP_001298079", "refseq_name": "protein mono-ADP-ribosyltransferase PARP3 isoform 1", "gene_name": "Parp3", "gene_names_uniprotkb": "Parp3; Adprt3", "gene_names_refseq": "A930002C11Rik; ADPRT-3; ARTD3; Adprt3; Adprtl3; PARP-3; Parp3; pADPRT-3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3ULW8", "url": "https://www.uniprot.org/uniprotkb/Q3ULW8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q3ULW8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3ULW8" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q3ULW8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3ULW8", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q3ULW8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q3ULW8" } ] } ], "all_sites": [], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70293-1.484.484", "start_pos": 484, "end_pos": 484, "uniprot_canonical_ac": "O70293-1", "length": 576, "uniprot_id": "GRK6_MOUSE", "protein_name": "G protein-coupled receptor kinase 6", "refseq_ac": "NP_001033107", "refseq_name": "G protein-coupled receptor kinase 6 isoform a", "gene_name": "Grk6", "gene_names_uniprotkb": "Grk6; Gprk6", "gene_names_refseq": "Gprk6; Grk6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PFKPDPQAIYCKDVLDIEQF", "down_seq": "TVKGVDLEPTDQDFYQKFAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "site_lbl": "Ser484" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "484", "end_pos": "484" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "568", "end_pos": "568" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "upstream", "id": "O70293-1.485.485", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70293-1.485.485", "start_pos": 485, "end_pos": 485, "uniprot_canonical_ac": "O70293-1", "length": 576, "uniprot_id": "GRK6_MOUSE", "protein_name": "G protein-coupled receptor kinase 6", "refseq_ac": "NP_001033107", "refseq_name": "G protein-coupled receptor kinase 6 isoform a", "gene_name": "Grk6", "gene_names_uniprotkb": "Grk6; Gprk6", "gene_names_refseq": "Gprk6; Grk6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FKPDPQAIYCKDVLDIEQFS", "down_seq": "VKGVDLEPTDQDFYQKFATG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "site_lbl": "Thr485" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "484", "end_pos": "484" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "568", "end_pos": "568" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 1, "direction": "downstream", "id": "O70293-1.484.484", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70293-1.566.566", "start_pos": 566, "end_pos": 566, "uniprot_canonical_ac": "O70293-1", "length": 576, "uniprot_id": "GRK6_MOUSE", "protein_name": "G protein-coupled receptor kinase 6", "refseq_ac": "NP_001033107", "refseq_name": "G protein-coupled receptor kinase 6 isoform a", "gene_name": "Grk6", "gene_names_uniprotkb": "Grk6; Gprk6", "gene_names_refseq": "Gprk6; Grk6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPKKGLLQRLFSRQDCCGNC", "down_seq": "DSEEELPTRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "site_lbl": "Ser566" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "484", "end_pos": "484" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "568", "end_pos": "568" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "O70293-1.568.568", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O70293-1.568.568", "start_pos": 568, "end_pos": 568, "uniprot_canonical_ac": "O70293-1", "length": 576, "uniprot_id": "GRK6_MOUSE", "protein_name": "G protein-coupled receptor kinase 6", "refseq_ac": "NP_001033107", "refseq_name": "G protein-coupled receptor kinase 6 isoform a", "gene_name": "Grk6", "gene_names_uniprotkb": "Grk6; Gprk6", "gene_names_refseq": "Gprk6; Grk6", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KKGLLQRLFSRQDCCGNCSD", "down_seq": "EEELPTRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O70293", "url": "https://www.uniprot.org/uniprotkb/O70293" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "O70293", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70293" } ], "site_lbl": "Ser568" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "484", "end_pos": "484" }, { "start_pos": "485", "end_pos": "485" }, { "start_pos": "566", "end_pos": "566" }, { "start_pos": "568", "end_pos": "568" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "O70293-1.566.566", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q912-1.374.374", "start_pos": 374, "end_pos": 374, "uniprot_canonical_ac": "E9Q912-1", "length": 607, "uniprot_id": "GDS1_MOUSE", "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1", "refseq_ac": "NP_001273688", "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1 isoform c", "gene_name": "Rap1gds1", "gene_names_uniprotkb": "Rap1gds1", "gene_names_refseq": "GDS1; Rap1gds1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q912", "url": "https://www.uniprot.org/uniprotkb/E9Q912" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VDNGIVEKLMDLLDRHVEDG", "down_seq": "VTVQHAALSALRNLAIPVVN", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "HVEDGNVTVQHAALSALR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn374", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "374", "end_pos": "374" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "589", "end_pos": "589" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q912-1.3.3", "start_pos": 3, "end_pos": 3, "uniprot_canonical_ac": "E9Q912-1", "length": 607, "uniprot_id": "GDS1_MOUSE", "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1", "refseq_ac": "NP_001273688", "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1 isoform c", "gene_name": "Rap1gds1", "gene_names_uniprotkb": "Rap1gds1", "gene_names_refseq": "GDS1; Rap1gds1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q912", "url": "https://www.uniprot.org/uniprotkb/E9Q912" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MD", "down_seq": "LSDTLKKLKITAADRTEGSL", "glycosylation": [ { "glytoucan_ac": "G41247ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DNLSDTLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn3", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "374", "end_pos": "374" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "589", "end_pos": "589" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "E9Q912-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q912-1.589.589", "start_pos": 589, "end_pos": 589, "uniprot_canonical_ac": "E9Q912-1", "length": 607, "uniprot_id": "GDS1_MOUSE", "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1", "refseq_ac": "NP_001273688", "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1 isoform c", "gene_name": "Rap1gds1", "gene_names_uniprotkb": "Rap1gds1", "gene_names_refseq": "GDS1; Rap1gds1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q912", "url": "https://www.uniprot.org/uniprotkb/E9Q912" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YKEVQDLAFLDVVSKLRSHE", "down_seq": "KSVAQQASLTEQRLTVES", "glycosylation": [ { "glytoucan_ac": "G50282JC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SHENKSVAQQASLTEQR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn589", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "374", "end_pos": "374" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "589", "end_pos": "589" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q912-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "E9Q912-1", "length": 607, "uniprot_id": "GDS1_MOUSE", "protein_name": "Rap1 GTPase-GDP dissociation stimulator 1", "refseq_ac": "NP_001273688", "refseq_name": "rap1 GTPase-GDP dissociation stimulator 1 isoform c", "gene_name": "Rap1gds1", "gene_names_uniprotkb": "Rap1gds1", "gene_names_refseq": "GDS1; Rap1gds1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q912", "url": "https://www.uniprot.org/uniprotkb/E9Q912" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers.", "journal": "Redox biology", "date": "2025-07-16", "authors": "Lanzillotta Chiara, Prestia Francesca, Greco Viviana, Iavarone Federica, Cordella Federica, Sette Chiara, Forte Elena, Tramutola Antonella, Lanzillotta Simona, Cassano Tommaso, Di Angelantonio Silvia, Urbani Andrea, Barone Eugenio, Perluigi Marzia, Di Domenico Fabio", "evidence": [ { "database": "O-GlcNAc Database", "id": "E9Q912", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q912" } ], "reference": [ { "type": "PubMed", "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658" } ] } ], "crossref": [ { "id": "40684658", "url": "https://glygen.org/publication/PubMed/40684658", "database": "PubMed", "categories": [ "Other" ] }, { "id": "E9Q912", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q912", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40684658", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40684658" }, { "id": "E9Q912", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=E9Q912" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "374", "end_pos": "374" }, { "start_pos": "3", "end_pos": "3" }, { "start_pos": "589", "end_pos": "589" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "E9Q912-1.3.3", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ18-1.261.261", "start_pos": 261, "end_pos": 261, "uniprot_canonical_ac": "Q6ZQ18-1", "length": 817, "uniprot_id": "EFR3B_MOUSE", "protein_name": "Protein EFR3 homolog B", "refseq_ac": "NP_001075952", "refseq_name": "protein EFR3 homolog B", "gene_name": "Efr3b", "gene_names_uniprotkb": "Efr3b; Kiaa0953", "gene_names_refseq": "C030014M07Rik; Efr3b; mKIAA0953", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GRAAFGNIKNAIKPVLIHLD", "down_seq": "HSLWEPKVFATRCFKIIMYS", "glycosylation": [ { "glytoucan_ac": "G84349RE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "AAFGNIKNAIKPVLIHLDNHSLWEPK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn261", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "331", "end_pos": "331" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ18-1.331.331", "start_pos": 331, "end_pos": 331, "uniprot_canonical_ac": "Q6ZQ18-1", "length": 817, "uniprot_id": "EFR3B_MOUSE", "protein_name": "Protein EFR3 homolog B", "refseq_ac": "NP_001075952", "refseq_name": "protein EFR3 homolog B", "gene_name": "Efr3b", "gene_names_uniprotkb": "Efr3b; Kiaa0953", "gene_names_refseq": "C030014M07Rik; Efr3b; mKIAA0953", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GIVEVLSEAAIIAATGSVGP", "down_seq": "VLEMFNTLLRQLRLSIDYAL", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr331", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "331", "end_pos": "331" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6ZQ18-1.212.212", "start_pos": 212, "end_pos": 212, "uniprot_canonical_ac": "Q6ZQ18-1", "length": 817, "uniprot_id": "EFR3B_MOUSE", "protein_name": "Protein EFR3 homolog B", "refseq_ac": "NP_001075952", "refseq_name": "protein EFR3 homolog B", "gene_name": "Efr3b", "gene_names_uniprotkb": "Efr3b; Kiaa0953", "gene_names_refseq": "C030014M07Rik; Efr3b; mKIAA0953", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" }, { "database": "iPTMnet", "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HMDKIVPSLLFNLQHVEEAE", "down_seq": "RSPSPLQAPEKEKENPAELA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18" } ], "site_lbl": "Ser212" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "331", "end_pos": "331" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "Q6ZQ18-1.214.214", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q6ZQ18-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ18-1.214.214", "start_pos": 214, "end_pos": 214, "uniprot_canonical_ac": "Q6ZQ18-1", "length": 817, "uniprot_id": "EFR3B_MOUSE", "protein_name": "Protein EFR3 homolog B", "refseq_ac": "NP_001075952", "refseq_name": "protein EFR3 homolog B", "gene_name": "Efr3b", "gene_names_uniprotkb": "Efr3b; Kiaa0953", "gene_names_refseq": "C030014M07Rik; Efr3b; mKIAA0953", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" }, { "database": "iPTMnet", "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DKIVPSLLFNLQHVEEAESR", "down_seq": "PSPLQAPEKEKENPAELAER", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18" } ], "site_lbl": "Ser214" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "331", "end_pos": "331" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "Q6ZQ18-1.212.212", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q6ZQ18-1.216.216", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6ZQ18-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "Q6ZQ18-1", "length": 817, "uniprot_id": "EFR3B_MOUSE", "protein_name": "Protein EFR3 homolog B", "refseq_ac": "NP_001075952", "refseq_name": "protein EFR3 homolog B", "gene_name": "Efr3b", "gene_names_uniprotkb": "Efr3b; Kiaa0953", "gene_names_refseq": "C030014M07Rik; Efr3b; mKIAA0953", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" }, { "database": "iPTMnet", "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IVPSLLFNLQHVEEAESRSP", "down_seq": "PLQAPEKEKENPAELAERCL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6ZQ18", "url": "https://www.uniprot.org/uniprotkb/Q6ZQ18" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q6ZQ18", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6ZQ18" } ], "site_lbl": "Ser216" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "261", "end_pos": "261" }, { "start_pos": "331", "end_pos": "331" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "212", "end_pos": "212" }, { "start_pos": "214", "end_pos": "214" }, { "start_pos": "216", "end_pos": "216" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "Q6ZQ18-1.212.212", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q6ZQ18-1.214.214", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6A0A9-1.1059.1059", "start_pos": 1059, "end_pos": 1059, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SAVSLAENGVMAEEKPVPQL", "down_seq": "GSTGDPRVPSHSESALNNDS", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "PVPQLNGSTGDPR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1059", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q6A0A9-1.1042.1042", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6A0A9-1.386.386", "start_pos": 386, "end_pos": 386, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "IPQTSLQAKPAVPQVPSPGG", "down_seq": "PGQAPYPYSLSEPALTLDTS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6A0A9-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q6A0A9", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q6A0A9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q6A0A9" }, { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q6A0A9-1.185.185", "start_pos": 185, "end_pos": 185, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389280376", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389280376", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "DHHQEVIGFCRENGFHGLVA", "down_seq": "DSDYALCNIPYYFSAHALKL", "snv": [ { "evidence": [ { "id": "rs3389280376", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389280376" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "Y", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (YDS->NDS).", "chr_id": "13", "chr_pos": "49102701", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y185", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6A0A9-1.1021.1021", "start_pos": 1021, "end_pos": 1021, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YYGRGYKSQGAIQGRPPYAA", "down_seq": "AEEVAKELKSKSGESKSSAV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "site_lbl": "Ser1021" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6A0A9-1.1042.1042", "start_pos": 1042, "end_pos": 1042, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AEEVAKELKSKSGESKSSAV", "down_seq": "LAENGVMAEEKPVPQLNGST", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "site_lbl": "Ser1042" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "Q6A0A9-1.1059.1059", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6A0A9-1.653.653", "start_pos": 653, "end_pos": 653, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PEFSPLIIKEWAAYKGKSPQ", "down_seq": "PELVEALAFREWTCPNLKRL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "site_lbl": "Thr653" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q6A0A9-1.958.958", "start_pos": 958, "end_pos": 958, "uniprot_canonical_ac": "Q6A0A9-1", "length": 1112, "uniprot_id": "F120A_MOUSE", "protein_name": "Constitutive coactivator of PPAR-gamma-like protein 1", "refseq_ac": "NP_001028440", "refseq_name": "constitutive coactivator of PPAR-gamma-like protein 1", "gene_name": "FAM120A", "gene_names_uniprotkb": "FAM120A; Kiaa0183; Ossa", "gene_names_refseq": "C9orf10; Fam120a; Ossa", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IPSQGGKLEIAGTVVGHWAG", "down_seq": "RRGRGGRGPFPLQVVSVGGP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q6A0A9", "url": "https://www.uniprot.org/uniprotkb/Q6A0A9" } ], "site_lbl": "Ser958" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1059", "end_pos": "1059" }, { "start_pos": "386", "end_pos": "386" } ] }, { "type": "snv", "site_list": [ { "start_pos": "185", "end_pos": "185" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1021", "end_pos": "1021" }, { "start_pos": "1042", "end_pos": "1042" }, { "start_pos": "653", "end_pos": "653" }, { "start_pos": "958", "end_pos": "958" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q80WS3-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q80WS3-1", "length": 314, "uniprot_id": "FBLL1_MOUSE", "protein_name": "RNA 2'-O-methyltransferase FBLL1", "refseq_ac": "NP_001004147", "refseq_name": "RNA 2'-O-methyltransferase FBLL1", "gene_name": "Fbll1", "gene_names_uniprotkb": "Fbll1", "gene_names_refseq": "Fbll1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80WS3", "url": "https://www.uniprot.org/uniprotkb/Q80WS3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q80WS3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80WS3" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q80WS3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80WS3", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "Q80WS3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q80WS3" } ] } ], "all_sites": [], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.106.106", "start_pos": 106, "end_pos": 106, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TGPVLEHPDCLPCRDCSSKA", "down_seq": "SSGGVWKDNINMALLVDTYY", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ANSSGGVWK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn106", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn106", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.1169.1169", "start_pos": 1169, "end_pos": 1169, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GSPLVVLPYMKHGDLRNFIR", "down_seq": "ETHNPTVKDLIGFGLQVAKG", "glycosylation": [ { "glytoucan_ac": "G31852PQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NETHNPTVK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1169", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.201.201", "start_pos": 201, "end_pos": 201, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AKVLLSEKDRFINFFVGNTI", "down_seq": "SSYPPGYSLHSISVRRLKET", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn201", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P16056-1.203.203", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.357.357", "start_pos": 357, "end_pos": 357, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SDDILFGVFAQSKPDSAEPV", "down_seq": "RSAVCAFPIKYVNDFFNKIV", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "QIGASPSDDILFGVFAQSKPDSAEPVNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn357", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn357", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.398.398", "start_pos": 398, "end_pos": 398, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3388814678", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388814678", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NKNNVRCLQHFYGPNHEHCF", "down_seq": "RTLLRNSSGCEARSDEYRTE", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn398", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388814678", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388814678" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NRT->IRT).", "chr_id": "6", "chr_pos": "17492432", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N398", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "upstream", "id": "P16056-1.404.404", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.404.404", "start_pos": 404, "end_pos": 404, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CLQHFYGPNHEHCFNRTLLR", "down_seq": "SSGCEARSDEYRTEFTTALQ", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn404", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P16056-1.398.398", "categories": [ "glycosylation_flag", "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.45.45", "start_pos": 45, "end_pos": 45, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "ECKEALVKSEMNVNMKYQLP", "down_seq": "FTAETPIQNVVLHGHHIYLG", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn45", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.581.581", "start_pos": 581, "end_pos": 581, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LPAVYKVFPTSAPLEGGTVL", "down_seq": "ICGWDFGFRKNNKFDLRKTK", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr581", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.606.606", "start_pos": 606, "end_pos": 606, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DFGFRKNNKFDLRKTKVLLG", "down_seq": "ESCTLTLSESTTNTLKCTVG", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn606", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.634.634", "start_pos": 634, "end_pos": 634, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SESTTNTLKCTVGPAMSEHF", "down_seq": "VSVIISNSRETTQYSAFSYV", "glycosylation": [ { "glytoucan_ac": "G95177YH", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "CTVGPAMSEHFNVSVIISNSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn634", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn634", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.675.675", "start_pos": 675, "end_pos": 675, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DPVITSISPRYGPQAGGTLL", "down_seq": "LTGKYLNSGNSRHISIGGKT", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.760.760", "start_pos": 760, "end_pos": 760, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "DPVVYEIHPTKSFISGGSTI", "down_seq": "GIGKTLNSVSLPKLVIDVHE", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (Man) threonine", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr760", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.784.784", "start_pos": 784, "end_pos": 784, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KTLNSVSLPKLVIDVHEVGV", "down_seq": "YTVACQHRSNSEIICCTTPS", "glycosylation": [ { "glytoucan_ac": "G07755XJ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LVIDVHEVGVNYTVACQHR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn784", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn784", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.878.878", "start_pos": 878, "end_pos": 878, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EIKGNNIDPEAVKGEVLKVG", "down_seq": "QSCESLHWHSGAVLCTVPSD", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn878", "evidence": [ { "id": "P16056", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16056#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1232.1232", "start_pos": 1232, "end_pos": 1232, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "MET mutation causes muscular dysplasia and\u00a0arthrogryposis.", "journal": "EMBO molecular medicine", "date": "2019-03", "authors": "Zhou Hang, Lian Chengjie, Wang Tingting, Yang Xiaoming, Xu Caixia, Su Deying, Zheng Shuhui, Huang Xiangyu, Liao Zhiheng, Zhou Taifeng, Qiu Xianjian, Chen Yuyu, Gao Bo, Li Yongyong, Wang Xudong, You Guoling, Fu Qihua, Gurnett Christina, Huang Dongsheng, Su Peiqiang", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "reference": [ { "type": "PubMed", "id": "30777867", "url": "https://glygen.org/publication/PubMed/30777867" } ] } ], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "30777867", "url": "https://glygen.org/publication/PubMed/30777867", "database": "PubMed", "categories": [ "Other" ] }, { "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "EKFTVKVADFGLARDMYDKE", "down_seq": "YSVHNKTGAKLPVKWMALES", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "C", "comment": "Mice heterozygous for the mutation show reduced number of myofibers in appendicular and axial muscles, defective migration of muscle progenitor cells and impaired proliferation of secondary myoblasts.", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" }, { "database": "PubMed", "id": "30777867", "url": "https://glygen.org/publication/PubMed/30777867" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0" }, { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Tyr1232" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "downstream", "id": "P16056-1.1228.1228", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "P16056-1.1233.1233", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P16056-1.203.203", "start_pos": 203, "end_pos": 203, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388808782", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388808782", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VLLSEKDRFINFFVGNTINS", "down_seq": "YPPGYSLHSISVRRLKETQD", "snv": [ { "evidence": [ { "id": "rs3388808782", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388808782" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "F", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NSS->NSF).", "chr_id": "6", "chr_pos": "17491847", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S203", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P16056-1.201.201", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1001.1001", "start_pos": 1001, "end_pos": 1001, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LVSARSVSPTTEMVSNESVD", "down_seq": "RATFPEDQFPNSSQNGACRQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Tyr1001" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P16056-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P16056-1.995.995", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P16056-1.998.998", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1228.1228", "start_pos": 1228, "end_pos": 1228, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "CMLDEKFTVKVADFGLARDM", "down_seq": "DKEYYSVHNKTGAKLPVKWM", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Tyr1228" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 4, "direction": "upstream", "id": "P16056-1.1232.1232", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P16056-1.1233.1233", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1233.1233", "start_pos": 1233, "end_pos": 1233, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "KFTVKVADFGLARDMYDKEY", "down_seq": "SVHNKTGAKLPVKWMALESL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" }, { "database": "UniProtKB", "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0" } ], "site_lbl": "Tyr1233" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P16056-1.1228.1228", "categories": [ "phosphorylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "P16056-1.1232.1232", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1287.1287", "start_pos": 1287, "end_pos": 1287, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FGVLLWELMTRGAPPYPDVN", "down_seq": "FDITIYLLQGRRLLQPEYCP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Thr1287" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1347.1347", "start_pos": 1347, "end_pos": 1347, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "SFSELVSRISSIFSTFIGEH", "down_seq": "VHVNATYVNVKCVAPYPSLL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0" }, { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Tyr1347" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P16056-1.1354.1354", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P16056-1.1363.1363", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1354.1354", "start_pos": 1354, "end_pos": 1354, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "RISSIFSTFIGEHYVHVNAT", "down_seq": "VNVKCVAPYPSLLPSQDNID", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "F8VQL0", "url": "https://www.uniprot.org/uniprotkb/F8VQL0" }, { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Tyr1354" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P16056-1.1347.1347", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "P16056-1.1363.1363", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.1363.1363", "start_pos": 1363, "end_pos": 1363, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "IGEHYVHVNATYVNVKCVAP", "down_seq": "PSLLPSQDNIDGEGNT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Tyr1363" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P16056-1.1347.1347", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "P16056-1.1354.1354", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.964.964", "start_pos": 964, "end_pos": 964, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VLLLSGLFLWMRKRKHKDLG", "down_seq": "ELVRYDARVHTPHLDRLVSA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Ser964" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P16056-1.975.975", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.975.975", "start_pos": 975, "end_pos": 975, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "RKRKHKDLGSELVRYDARVH", "down_seq": "PHLDRLVSARSVSPTTEMVS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Thr975" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P16056-1.964.964", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P16056-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 20, "direction": "upstream", "id": "P16056-1.995.995", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.988.988", "start_pos": 988, "end_pos": 988, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RYDARVHTPHLDRLVSARSV", "down_seq": "PTTEMVSNESVDYRATFPED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Ser988" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P16056-1.975.975", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "P16056-1.995.995", "categories": [ "phosphorylation_flag" ] }, { "distance": 10, "direction": "upstream", "id": "P16056-1.998.998", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P16056-1.1001.1001", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.995.995", "start_pos": 995, "end_pos": 995, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TPHLDRLVSARSVSPTTEMV", "down_seq": "NESVDYRATFPEDQFPNSSQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Ser995" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "P16056-1.975.975", "categories": [ "phosphorylation_flag" ] }, { "distance": 7, "direction": "downstream", "id": "P16056-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P16056-1.998.998", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P16056-1.1001.1001", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P16056-1.998.998", "start_pos": 998, "end_pos": 998, "uniprot_canonical_ac": "P16056-1", "length": 1379, "uniprot_id": "MET_MOUSE", "protein_name": "Hepatocyte growth factor receptor", "refseq_ac": "", "refseq_name": "", "gene_name": "Met", "gene_names_uniprotkb": "Met", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LDRLVSARSVSPTTEMVSNE", "down_seq": "VDYRATFPEDQFPNSSQNGA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P16056", "url": "https://www.uniprot.org/uniprotkb/P16056" } ], "site_lbl": "Ser998" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "106", "end_pos": "106" }, { "start_pos": "1169", "end_pos": "1169" }, { "start_pos": "201", "end_pos": "201" }, { "start_pos": "357", "end_pos": "357" }, { "start_pos": "398", "end_pos": "398" }, { "start_pos": "404", "end_pos": "404" }, { "start_pos": "45", "end_pos": "45" }, { "start_pos": "581", "end_pos": "581" }, { "start_pos": "606", "end_pos": "606" }, { "start_pos": "634", "end_pos": "634" }, { "start_pos": "675", "end_pos": "675" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "784", "end_pos": "784" }, { "start_pos": "878", "end_pos": "878" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "1232", "end_pos": "1232" } ] }, { "type": "snv", "site_list": [ { "start_pos": "203", "end_pos": "203" }, { "start_pos": "398", "end_pos": "398" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1001", "end_pos": "1001" }, { "start_pos": "1228", "end_pos": "1228" }, { "start_pos": "1232", "end_pos": "1232" }, { "start_pos": "1233", "end_pos": "1233" }, { "start_pos": "1287", "end_pos": "1287" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1354", "end_pos": "1354" }, { "start_pos": "1363", "end_pos": "1363" }, { "start_pos": "964", "end_pos": "964" }, { "start_pos": "975", "end_pos": "975" }, { "start_pos": "988", "end_pos": "988" }, { "start_pos": "995", "end_pos": "995" }, { "start_pos": "998", "end_pos": "998" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 10, "direction": "downstream", "id": "P16056-1.988.988", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "P16056-1.995.995", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "P16056-1.1001.1001", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O08756-1.64.64", "start_pos": 64, "end_pos": 64, "uniprot_canonical_ac": "O08756-1", "length": 261, "uniprot_id": "HCD2_MOUSE", "protein_name": "3-hydroxyacyl-CoA dehydrogenase type-2", "refseq_ac": "", "refseq_name": "", "gene_name": "Hsd17b10", "gene_names_uniprotkb": "Hsd17b10; Erab; Hadh2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O08756", "url": "https://www.uniprot.org/uniprotkb/O08756" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DSEGESQAKKLGESCIFAPA", "down_seq": "VTSEKEIQAALTLAKEKFGR", "glycosylation": [ { "glytoucan_ac": "G23194RE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LVGQGATAVLLDVPDSEGESQAKKLGESCIFAPANVTSEK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn64", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "64", "end_pos": "64" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O08756-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "O08756-1", "length": 261, "uniprot_id": "HCD2_MOUSE", "protein_name": "3-hydroxyacyl-CoA dehydrogenase type-2", "refseq_ac": "", "refseq_name": "", "gene_name": "Hsd17b10", "gene_names_uniprotkb": "Hsd17b10; Erab; Hadh2", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O08756", "url": "https://www.uniprot.org/uniprotkb/O08756" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "O08756", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O08756" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "O08756", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O08756" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "O08756", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O08756" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O08756", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O08756", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "O08756", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O08756" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "64", "end_pos": "64" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SSRYQLKGDLNKGDVSLIIK", "down_seq": "VTLDDHGTYCCRIQFPGLMN", "glycosylation": [ { "glytoucan_ac": "G10846ZT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NVTLDDHGTYCCR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn100", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn100", "evidence": [ { "id": "Q8VIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "Q8VIM0-1.112.112", "categories": [ "mutagenesis_flag" ] }, { "distance": 18, "direction": "upstream", "id": "Q8VIM0-1.118.119", "categories": [ "mutagenesis_flag" ] }, { "distance": 20, "direction": "upstream", "id": "Q8VIM0-1.120.121", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.146.146", "start_pos": 146, "end_pos": 146, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LKLDIKAAKVTPAQTAHGDS", "down_seq": "TASPRTLTTERNGSETQTLV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GalNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GalNAc...) threonine;O-GalNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr146", "evidence": [ { "id": "Q8VIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VIM0-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TLTTERNGSETQTLVTLHNN", "down_seq": "GTKISTWADEIKDSGETIRT", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn172", "evidence": [ { "id": "Q8VIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VIM0-1.74.74", "start_pos": 74, "end_pos": 74, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GKGFCPWSQCTNELLRTDER", "down_seq": "VTYQKSSRYQLKGDLNKGDV", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn74", "evidence": [ { "id": "Q8VIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8VIM0-1.60.62", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q8VIM0-1.62.62", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8VIM0-1.112.112", "start_pos": 112, "end_pos": 112, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.", "journal": "Blood", "date": "2009", "authors": "Nakayama M, Akiba H, Takeda K, Kojima Y, Hashiguchi M, Azuma M, Yagita H, Okumura K", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "GDVSLIIKNVTLDDHGTYCC", "down_seq": "IQFPGLMNDKKLELKLDIKA", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes phagocytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q8VIM0-1.100.100", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8VIM0-1.118.119", "categories": [ "mutagenesis_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q8VIM0-1.120.121", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.118.119", "start_pos": 118, "end_pos": 119, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2010", "authors": "DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "LM", "start_aa": "L", "up_seq": "IKNVTLDDHGTYCCRIQFPG", "down_seq": "NDKKLELKLDIKAAKVTPAQ", "mutagenesis": [ { "sequence_org": "LM", "sequence_mut": "AA", "comment": "Decreases phosphatidylserine binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "Q8VIM0-1.100.100", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8VIM0-1.112.112", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8VIM0-1.120.121", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.120.121", "start_pos": 120, "end_pos": 121, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2010", "authors": "DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] }, { "title": "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.", "journal": "Blood", "date": "2009", "authors": "Nakayama M, Akiba H, Takeda K, Kojima Y, Hashiguchi M, Azuma M, Yagita H, Okumura K", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "ND", "start_aa": "N", "up_seq": "NVTLDDHGTYCCRIQFPGLM", "down_seq": "KKLELKLDIKAAKVTPAQTA", "mutagenesis": [ { "sequence_org": "ND", "sequence_mut": "AA", "comment": "Decreases phosphatidylserine binding, abolishes phagocytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" }, { "database": "PubMed", "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 20, "direction": "downstream", "id": "Q8VIM0-1.100.100", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "Q8VIM0-1.112.112", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8VIM0-1.118.119", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.256.256", "start_pos": 256, "end_pos": 256, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Bat3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion.", "journal": "Nature medicine", "date": "2012", "authors": "Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, Kuchroo VK", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "22863785", "url": "https://glygen.org/publication/PubMed/22863785" } ] }, { "title": "Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways.", "journal": "Molecular and cellular biology", "date": "2011", "authors": "Lee J, Su EW, Zhu C, Hainline S, Phuah J, Moroco JA, Smithgall TE, Kuchroo VK, Kane LP", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "21807895", "url": "https://glygen.org/publication/PubMed/21807895" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22863785", "url": "https://glygen.org/publication/PubMed/22863785", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21807895", "url": "https://glygen.org/publication/PubMed/21807895", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "LPPGGLANAGAVRIRSEENI", "down_seq": "TIEENVYEVENSNEYYCYVN", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes phosphorylation, disrupts interaction with PIK3R1 and PIK3R2, no LGALS9-mediated disruption of interaction with BAG6; when associated with F-263.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "22863785", "url": "https://glygen.org/publication/PubMed/22863785" }, { "database": "PubMed", "id": "21807895", "url": "https://glygen.org/publication/PubMed/21807895" } ] } ], "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by ITK", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "site_lbl": "Tyr256" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag", "phosphorylation_flag" ], "glycosylation": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "Q8VIM0-1.263.263", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.263.263", "start_pos": 263, "end_pos": 263, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Bat3 promotes T cell responses and autoimmunity by repressing Tim-3-mediated cell death and exhaustion.", "journal": "Nature medicine", "date": "2012", "authors": "Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, Kuchroo VK", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "22863785", "url": "https://glygen.org/publication/PubMed/22863785" } ] }, { "title": "Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways.", "journal": "Molecular and cellular biology", "date": "2011", "authors": "Lee J, Su EW, Zhu C, Hainline S, Phuah J, Moroco JA, Smithgall TE, Kuchroo VK, Kane LP", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "21807895", "url": "https://glygen.org/publication/PubMed/21807895" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22863785", "url": "https://glygen.org/publication/PubMed/22863785", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21807895", "url": "https://glygen.org/publication/PubMed/21807895", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "NAGAVRIRSEENIYTIEENV", "down_seq": "EVENSNEYYCYVNSQQPS", "mutagenesis": [ { "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes phosphorylation, disrupts interaction with PIK3R1 and PIK3R2, no LGALS9-mediated disruption of interaction with BAG6; when associated with F-256.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "22863785", "url": "https://glygen.org/publication/PubMed/22863785" }, { "database": "PubMed", "id": "21807895", "url": "https://glygen.org/publication/PubMed/21807895" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q8VIM0-1.256.256", "categories": [ "mutagenesis_flag", "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.53.53", "start_pos": 53, "end_pos": 53, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2010", "authors": "DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "W", "start_aa": "W", "up_seq": "NAYLPCSYTLSTPGALVPMC", "down_seq": "GKGFCPWSQCTNELLRTDER", "mutagenesis": [ { "sequence_org": "W", "sequence_mut": "A", "comment": "Greatly decreases phosphatidylserine binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "Q8VIM0-1.60.62", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8VIM0-1.62.62", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.60.62", "start_pos": 60, "end_pos": 62, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2010", "authors": "DeKruyff RH, Bu X, Ballesteros A, Santiago C, Chim YL, Lee HH, Karisola P, Pichavant M, Kaplan GG, Umetsu DT, Freeman GJ, Casasnovas JM", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "WSQ", "start_aa": "W", "up_seq": "YTLSTPGALVPMCWGKGFCP", "down_seq": "CTNELLRTDERNVTYQKSSR", "mutagenesis": [ { "sequence_org": "WSQ", "sequence_mut": "VFE", "comment": "Decreases phosphatidylserine binding.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "20083673", "url": "https://glygen.org/publication/PubMed/20083673" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "Q8VIM0-1.53.53", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "upstream", "id": "Q8VIM0-1.62.62", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VIM0-1.74.74", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8VIM0-1.62.62", "start_pos": 62, "end_pos": 62, "uniprot_canonical_ac": "Q8VIM0-1", "length": 281, "uniprot_id": "HAVR2_MOUSE", "protein_name": "Hepatitis A virus cellular receptor 2 homolog", "refseq_ac": "NP_599011", "refseq_name": "hepatitis A virus cellular receptor 2 homolog precursor", "gene_name": "Havcr2", "gene_names_uniprotkb": "Havcr2; Tim3; Timd3", "gene_names_refseq": "Havcr2; TIM-3; Tim3; Timd3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.", "journal": "Blood", "date": "2009", "authors": "Nakayama M, Akiba H, Takeda K, Kojima Y, Hashiguchi M, Azuma M, Yagita H, Okumura K", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" } ], "reference": [ { "type": "PubMed", "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762" } ] } ], "crossref": [ { "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Q", "start_aa": "Q", "up_seq": "LSTPGALVPMCWGKGFCPWS", "down_seq": "CTNELLRTDERNVTYQKSSR", "mutagenesis": [ { "sequence_org": "Q", "sequence_mut": "A", "comment": "No effect on phagocytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8VIM0", "url": "https://www.uniprot.org/uniprotkb/Q8VIM0" }, { "database": "PubMed", "id": "19224762", "url": "https://glygen.org/publication/PubMed/19224762" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "146", "end_pos": "146" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "74", "end_pos": "74" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "112", "end_pos": "112" }, { "start_pos": "118", "end_pos": "119" }, { "start_pos": "120", "end_pos": "121" }, { "start_pos": "256", "end_pos": "256" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "53", "end_pos": "53" }, { "start_pos": "60", "end_pos": "62" }, { "start_pos": "62", "end_pos": "62" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "256", "end_pos": "256" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8VIM0-1.53.53", "categories": [ "mutagenesis_flag" ] }, { "distance": 0, "direction": "downstream", "id": "Q8VIM0-1.60.62", "categories": [ "mutagenesis_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q8VIM0-1.74.74", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P30681-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P30681-1", "length": 210, "uniprot_id": "HMGB2_MOUSE", "protein_name": "High mobility group protein B2", "refseq_ac": "NP_032278", "refseq_name": "high mobility group protein B2", "gene_name": "Hmgb2", "gene_names_uniprotkb": "Hmgb2; Hmg2", "gene_names_refseq": "HMG-2; Hmg2; Hmgb2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P30681", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P30681", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P30681" }, { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "35", "end_pos": "35" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P30681-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P30681-1", "length": 210, "uniprot_id": "HMGB2_MOUSE", "protein_name": "High mobility group protein B2", "refseq_ac": "NP_032278", "refseq_name": "high mobility group protein B2", "gene_name": "Hmgb2", "gene_names_uniprotkb": "Hmgb2; Hmg2", "gene_names_refseq": "HMG-2; Hmg2; Hmgb2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPKGDKKGKKKDPNAPKRPP", "down_seq": "AFFLFCSENRPKIKIEHPGL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681" } ], "site_lbl": "Ser100" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "35", "end_pos": "35" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P30681-1.35.35", "start_pos": 35, "end_pos": 35, "uniprot_canonical_ac": "P30681-1", "length": 210, "uniprot_id": "HMGB2_MOUSE", "protein_name": "High mobility group protein B2", "refseq_ac": "NP_032278", "refseq_name": "high mobility group protein B2", "gene_name": "Hmgb2", "gene_names_uniprotkb": "Hmgb2; Hmg2", "gene_names_refseq": "HMG-2; Hmg2; Hmgb2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SYAFFVQTCREEHKKKHPDS", "down_seq": "VNFAEFSKKCSERWKTMSAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P30681", "url": "https://www.uniprot.org/uniprotkb/P30681" } ], "site_lbl": "Ser35" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "35", "end_pos": "35" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17156-1.152.152", "start_pos": 152, "end_pos": 152, "uniprot_canonical_ac": "P17156-1", "length": 633, "uniprot_id": "HSP72_MOUSE", "protein_name": "Heat shock-related 70 kDa protein 2", "refseq_ac": "NP_001002012", "refseq_name": "heat shock-related 70 kDa protein 2", "gene_name": "Hspa2", "gene_names_uniprotkb": "Hspa2; Hcp70.2; Hsp70-2", "gene_names_refseq": "70kDa; HSP70.2; HSP70A2; Hsp70-2; Hspa2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AEAYLGGKVQSAVITVPAYF", "down_seq": "DSQRQATKDAGTITGLNVLR", "glycosylation": [ { "glytoucan_ac": "G11115RO", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "EIAEAYLGGKVQSAVITVPAYFNDSQR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn152", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "36", "end_pos": "36" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "403", "end_pos": "403" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "414", "end_pos": "414" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17156-1.36.36", "start_pos": 36, "end_pos": 36, "uniprot_canonical_ac": "P17156-1", "length": 633, "uniprot_id": "HSP72_MOUSE", "protein_name": "Heat shock-related 70 kDa protein 2", "refseq_ac": "NP_001002012", "refseq_name": "heat shock-related 70 kDa protein 2", "gene_name": "Hspa2", "gene_names_uniprotkb": "Hspa2; Hcp70.2; Hsp70-2", "gene_names_refseq": "70kDa; HSP70.2; HSP70A2; Hsp70-2; Hspa2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "YSCVGVFQHGKVEIIANDQG", "down_seq": "RTTPSYVAFTDTERLIGDAA", "glycosylation": [ { "glytoucan_ac": "G59354CW", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTER", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn36", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "36", "end_pos": "36" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "403", "end_pos": "403" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "414", "end_pos": "414" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17156-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P17156-1", "length": 633, "uniprot_id": "HSP72_MOUSE", "protein_name": "Heat shock-related 70 kDa protein 2", "refseq_ac": "NP_001002012", "refseq_name": "heat shock-related 70 kDa protein 2", "gene_name": "Hspa2", "gene_names_uniprotkb": "Hspa2; Hcp70.2; Hsp70-2", "gene_names_refseq": "70kDa; HSP70.2; HSP70A2; Hsp70-2; Hspa2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P17156", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17156" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P17156", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17156", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "P17156", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P17156" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "36", "end_pos": "36" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "403", "end_pos": "403" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "414", "end_pos": "414" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P17156-1.403.403", "start_pos": 403, "end_pos": 403, "uniprot_canonical_ac": "P17156-1", "length": 633, "uniprot_id": "HSP72_MOUSE", "protein_name": "Heat shock-related 70 kDa protein 2", "refseq_ac": "NP_001002012", "refseq_name": "heat shock-related 70 kDa protein 2", "gene_name": "Hspa2", "gene_names_uniprotkb": "Hspa2; Hcp70.2; Hsp70-2", "gene_names_refseq": "70kDa; HSP70.2; HSP70A2; Hsp70-2; Hspa2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LIGDKSENVQDLLLLDVTPL", "down_seq": "LGIETAGGVMTPLIKRNTTI", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "site_lbl": "Ser403" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "36", "end_pos": "36" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "403", "end_pos": "403" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "414", "end_pos": "414" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P17156-1.408.408", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "P17156-1.414.414", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17156-1.408.408", "start_pos": 408, "end_pos": 408, "uniprot_canonical_ac": "P17156-1", "length": 633, "uniprot_id": "HSP72_MOUSE", "protein_name": "Heat shock-related 70 kDa protein 2", "refseq_ac": "NP_001002012", "refseq_name": "heat shock-related 70 kDa protein 2", "gene_name": "Hspa2", "gene_names_uniprotkb": "Hspa2; Hcp70.2; Hsp70-2", "gene_names_refseq": "70kDa; HSP70.2; HSP70A2; Hsp70-2; Hspa2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "SENVQDLLLLDVTPLSLGIE", "down_seq": "AGGVMTPLIKRNTTIPTKQT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "site_lbl": "Thr408" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "36", "end_pos": "36" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "403", "end_pos": "403" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "414", "end_pos": "414" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P17156-1.403.403", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P17156-1.414.414", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P17156-1.414.414", "start_pos": 414, "end_pos": 414, "uniprot_canonical_ac": "P17156-1", "length": 633, "uniprot_id": "HSP72_MOUSE", "protein_name": "Heat shock-related 70 kDa protein 2", "refseq_ac": "NP_001002012", "refseq_name": "heat shock-related 70 kDa protein 2", "gene_name": "Hspa2", "gene_names_uniprotkb": "Hspa2; Hcp70.2; Hsp70-2", "gene_names_refseq": "70kDa; HSP70.2; HSP70A2; Hsp70-2; Hspa2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LLLLDVTPLSLGIETAGGVM", "down_seq": "PLIKRNTTIPTKQTQTFTTY", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P17156", "url": "https://www.uniprot.org/uniprotkb/P17156" } ], "site_lbl": "Thr414" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "152", "end_pos": "152" }, { "start_pos": "36", "end_pos": "36" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "403", "end_pos": "403" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "414", "end_pos": "414" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P17156-1.403.403", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "P17156-1.408.408", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99JP6-1.120.120", "start_pos": 120, "end_pos": 120, "uniprot_canonical_ac": "Q99JP6-1", "length": 356, "uniprot_id": "HOME3_MOUSE", "protein_name": "Homer protein homolog 3", "refseq_ac": "NP_001139625", "refseq_name": "homer protein homolog 3 isoform 1", "gene_name": "Homer3", "gene_names_uniprotkb": "Homer3", "gene_names_refseq": "Homer3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TQFAEKFQEVKEAARLAREK", "down_seq": "QDGGEFTSTGLALASHQVPP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6" } ], "site_lbl": "Ser120" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q99JP6-1.159.159", "start_pos": 159, "end_pos": 159, "uniprot_canonical_ac": "Q99JP6-1", "length": 356, "uniprot_id": "HOME3_MOUSE", "protein_name": "Homer protein homolog 3", "refseq_ac": "NP_001139625", "refseq_name": "homer protein homolog 3 isoform 1", "gene_name": "Homer3", "gene_names_uniprotkb": "Homer3", "gene_names_refseq": "Homer3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6" }, { "database": "iPTMnet", "id": "Q99JP6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99JP6" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q99JP6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99JP6", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PPSPLVSTNGPGEEKLFRSQ", "down_seq": "ADTPGPTERERLKKMLSEGS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99JP6", "url": "https://www.uniprot.org/uniprotkb/Q99JP6" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q99JP6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99JP6" } ], "site_lbl": "Ser159" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "120", "end_pos": "120" }, { "start_pos": "159", "end_pos": "159" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.135.135", "start_pos": 135, "end_pos": 135, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2016-04-12", "authors": "Blin Sandy, Ben Soussia Ismail, Kim Eun-Jin, Brau Fr\u00e9d\u00e9ric, Kang Dawon, Lesage Florian, Bichet Delphine", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "27035965", "url": "https://glygen.org/publication/PubMed/27035965" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27035965", "url": "https://glygen.org/publication/PubMed/27035965", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "G", "start_aa": "G", "up_seq": "CVSPQELETLIQHALDADNA", "down_seq": "VSPVGNSSNSSSHWDLGSAF", "mutagenesis": [ { "sequence_org": "G", "sequence_mut": "I", "comment": "Confers resistance to ruthenium red.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "27035965", "url": "https://glygen.org/publication/PubMed/27035965" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q8BUW1-1.148.148", "categories": [ "mutagenesis_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8BUW1-1.151.151", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.148.148", "start_pos": 148, "end_pos": 148, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "ALDADNAGVSPVGNSSNSSS", "down_seq": "WDLGSAFFFAGTVITTIGYG", "mutagenesis": [ { "sequence_org": "H", "sequence_mut": "A", "comment": "Decreased basal mean amplitude of channel current.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] }, { "sequence_org": "H", "sequence_mut": "K", "comment": "Increased basal mean amplitude of channel current.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8BUW1-1.135.135", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BUW1-1.151.151", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.151.151", "start_pos": 151, "end_pos": 151, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2016-04-12", "authors": "Levitz Joshua, Royal Perrine, Comoglio Yannick, Wdziekonski Brigitte, Schaub S\u00e9bastien, Clemens Daniel M, Isacoff Ehud Y, Sandoz Guillaume", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "L", "start_aa": "L", "up_seq": "ADNAGVSPVGNSSNSSSHWD", "down_seq": "GSAFFFAGTVITTIGYGNIA", "mutagenesis": [ { "sequence_org": "L", "sequence_mut": "A", "comment": "Mimics the deprotonated state and decreases the basal current. In heterodimer with KCNK2, it displays KCNK2-like pH dependence.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963" } ] }, { "sequence_org": "L", "sequence_mut": "K", "comment": "Mimics the protonated state and increases the basal current. In heterodimer with KCNK2, it displays KCNK2-like pH dependence.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "27035963", "url": "https://glygen.org/publication/PubMed/27035963" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "Q8BUW1-1.135.135", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BUW1-1.148.148", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.279.279", "start_pos": 279, "end_pos": 279, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "F", "start_aa": "F", "up_seq": "TALESIYFVVVTLTTVGFGD", "down_seq": "VAGGNAGINYREWYKPLVWF", "mutagenesis": [ { "sequence_org": "F", "sequence_mut": "Y", "comment": "No effect on extracellular pH sensing. Causes reduced inhibition induced by a pH shift from 7.2 to 8; when associated with S-284, D-285 and E-288. Inverts pH-dependent gating, with channel conductance being inhibited by acidic pH and activated by basic pH; when associated with S-284, D-285, E-288 and L-290.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "Q8BUW1-1.284.284", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BUW1-1.285.285", "categories": [ "mutagenesis_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8BUW1-1.288.288", "categories": [ "mutagenesis_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8BUW1-1.290.290", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.284.284", "start_pos": 284, "end_pos": 284, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IYFVVVTLTTVGFGDFVAGG", "down_seq": "AGINYREWYKPLVWFWILVG", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "S", "comment": "No effect on extracellular pH sensing. Causes reduced inhibition induced by a pH shift from 7.2 to 8; when associated with Y-279, D-285 and E-288. Inverts pH-dependent gating, with channel conductance being inhibited by acidic pH and activated by basic pH; when associated with Y-279, D-285, E-288 and L-290.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "Q8BUW1-1.279.279", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q8BUW1-1.285.285", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8BUW1-1.288.288", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q8BUW1-1.290.290", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.285.285", "start_pos": 285, "end_pos": 285, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "A", "start_aa": "A", "up_seq": "YFVVVTLTTVGFGDFVAGGN", "down_seq": "GINYREWYKPLVWFWILVGL", "mutagenesis": [ { "sequence_org": "A", "sequence_mut": "D", "comment": "No effect on extracellular pH sensing. Causes reduced inhibition induced by a pH shift from 7.2 to 8; when associated with S-279, S-284 and E-288. Inverts pH-dependent gating, with channel conductance being inhibited by acidic pH and activated by basic pH; when associated with Y-279, S-284, E-288 and L-290.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "Q8BUW1-1.279.279", "categories": [ "mutagenesis_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q8BUW1-1.284.284", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q8BUW1-1.288.288", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q8BUW1-1.290.290", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.288.288", "start_pos": 288, "end_pos": 288, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VVTLTTVGFGDFVAGGNAGI", "down_seq": "YREWYKPLVWFWILVGLAYF", "mutagenesis": [ { "sequence_org": "N", "sequence_mut": "E", "comment": "No effect on extracellular pH sensing. Causes reduced inhibition induced by a pH shift from 7.2 to 8; when associated with S-279, S-284 and D-285. Inverts pH-dependent gating, with channel conductance being inhibited by acidic pH and activated by basic pH; when associated with Y-279, S-284, D-285 and L-290.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q8BUW1-1.279.279", "categories": [ "mutagenesis_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8BUW1-1.284.284", "categories": [ "mutagenesis_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q8BUW1-1.285.285", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8BUW1-1.290.290", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8BUW1-1.290.290", "start_pos": 290, "end_pos": 290, "uniprot_canonical_ac": "Q8BUW1-1", "length": 535, "uniprot_id": "KCNKA_MOUSE", "protein_name": "Potassium channel subfamily K member 10", "refseq_ac": "NP_001303595", "refseq_name": "potassium channel subfamily K member 10 isoform 4", "gene_name": "Kcnk10", "gene_names_uniprotkb": "Kcnk10", "gene_names_refseq": "1700024D23Rik; 3010005K24Rik; Kcnk10; Trek2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009-08-25", "authors": "Sandoz Guillaume, Douguet Dominique, Chatelain Franck, Lazdunski Michel, Lesage Florian", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" } ], "reference": [ { "type": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "crossref": [ { "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "R", "start_aa": "R", "up_seq": "TLTTVGFGDFVAGGNAGINY", "down_seq": "EWYKPLVWFWILVGLAYFAA", "mutagenesis": [ { "sequence_org": "R", "sequence_mut": "L", "comment": "Loss of K(+) channel activity. Normal basal conductance but reduced inhibition induced by a pH shift from 7.2 to 8; when associated with Y-279. Inverts pH-dependent gating, with channel conductance being inhibited by acidic pH and activated by basic pH; when associated with Y-279, S-284, D-285 and E-288.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUW1", "url": "https://www.uniprot.org/uniprotkb/Q8BUW1" }, { "database": "PubMed", "id": "19667202", "url": "https://glygen.org/publication/PubMed/19667202" } ] } ], "all_sites": [ { "type": "mutagenesis", "site_list": [ { "start_pos": "135", "end_pos": "135" }, { "start_pos": "148", "end_pos": "148" }, { "start_pos": "151", "end_pos": "151" }, { "start_pos": "279", "end_pos": "279" }, { "start_pos": "284", "end_pos": "284" }, { "start_pos": "285", "end_pos": "285" }, { "start_pos": "288", "end_pos": "288" }, { "start_pos": "290", "end_pos": "290" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "Q8BUW1-1.279.279", "categories": [ "mutagenesis_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8BUW1-1.284.284", "categories": [ "mutagenesis_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q8BUW1-1.285.285", "categories": [ "mutagenesis_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8BUW1-1.288.288", "categories": [ "mutagenesis_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q2E4-1.1500.1500", "start_pos": 1500, "end_pos": 1500, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "ELLLHVTIAAQAGLTRSISG", "down_seq": "PAETPACKSASETKVASHAV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1500", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.3904.3904", "start_pos": 3904, "end_pos": 3904, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LEMDVALVQYINRLCRHLAI", "down_seq": "PARLHPHEVYLDPADAADPR", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3904", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.574.574", "start_pos": 574, "end_pos": 574, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LFGGTSGLSSLKILASSLVY", "down_seq": "ISDGQFASRADLIDAAGSSL", "glycosylation": [ { "glytoucan_ac": "G35253PZ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "ILASSLVYNISDGQFASR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn574", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q2E4-1.1009.1009", "start_pos": 1009, "end_pos": 1009, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388787427", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388787427", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "QTLTMADALMPQLVQLVLYT", "down_seq": "QTALLLKTQCPAFAEMSCSP", "snv": [ { "evidence": [ { "id": "rs3388787427", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388787427" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SQT->NQT).", "chr_id": "5", "chr_pos": "121435315", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S1009", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.1693.1693", "start_pos": 1693, "end_pos": 1693, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388792013", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388792013", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "ETMTSVVSLCARYPIACANS", "down_seq": "GLLCTIPYTRSEEKCLVRSG", "snv": [ { "evidence": [ { "id": "rs3388792013", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388792013" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NSI->NST).", "chr_id": "5", "chr_pos": "121448720", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I1693", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.3680.3680", "start_pos": 3680, "end_pos": 3680, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388783118", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388783118", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "KSIKGEKLVPGAREVLTEIF", "down_seq": "SCAHSEQTLSLTPAKPIRVS", "snv": [ { "evidence": [ { "id": "rs3388783118", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388783118" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KSC->NSC).", "chr_id": "5", "chr_pos": "121491603", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K3680", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.3789.3789", "start_pos": 3789, "end_pos": 3789, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388791969", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388791969", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "STKRPVTKPPAKDKAVLSSL", "down_seq": "RTALSEKKPTVKPKSPEKSK", "snv": [ { "evidence": [ { "id": "rs3388791969", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388791969" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (SRT->NRT).", "chr_id": "5", "chr_pos": "121492028", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S3789", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.3877.3877", "start_pos": 3877, "end_pos": 3877, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388789081", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388789081", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "SCGYDLHFERCACIDVRHAQ", "down_seq": "ASRKWTLEMDVALVQYINRL", "snv": [ { "evidence": [ { "id": "rs3388789081", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388789081" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KAS->NAS).", "chr_id": "5", "chr_pos": "121496240", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K3877", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E9Q2E4-1.930.930", "start_pos": 930, "end_pos": 930, "uniprot_canonical_ac": "E9Q2E4-1", "length": 4418, "uniprot_id": "E9Q2E4_MOUSE", "protein_name": "HECT domain E3 ubiquitin protein ligase 4", "refseq_ac": "NP_852086", "refseq_name": "probable E3 ubiquitin-protein ligase HECTD4", "gene_name": "Hectd4", "gene_names_uniprotkb": "Hectd4", "gene_names_refseq": "A130010L24; EG545802; Gm15800; Hectd4; mKIAA0614", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q2E4", "url": "https://www.uniprot.org/uniprotkb/E9Q2E4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388787036", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388787036", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "SLQGETLKELKTSILALATQ", "down_seq": "LTGCDEVLEMLQQVTTALIN", "snv": [ { "evidence": [ { "id": "rs3388787036", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388787036" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (ILT->NLT).", "chr_id": "5", "chr_pos": "121433475", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I930", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "1500", "end_pos": "1500" }, { "start_pos": "3904", "end_pos": "3904" }, { "start_pos": "574", "end_pos": "574" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1009", "end_pos": "1009" }, { "start_pos": "1693", "end_pos": "1693" }, { "start_pos": "3680", "end_pos": "3680" }, { "start_pos": "3789", "end_pos": "3789" }, { "start_pos": "3877", "end_pos": "3877" }, { "start_pos": "930", "end_pos": "930" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "D3Z1Y0-1.694.694", "start_pos": 694, "end_pos": 694, "uniprot_canonical_ac": "D3Z1Y0-1", "length": 860, "uniprot_id": "D3Z1Y0_MOUSE", "protein_name": "Cadherin related family member 18", "refseq_ac": "", "refseq_name": "", "gene_name": "Cdhr18", "gene_names_uniprotkb": "Cdhr18; Gm281", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "D3Z1Y0", "url": "https://www.uniprot.org/uniprotkb/D3Z1Y0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KTGTAVIDINVMRTSTPIPP", "down_seq": "SSEQRKGLTIVYTAINTYKS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr694", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "694", "end_pos": "694" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "E0CZ42-1.657.657", "start_pos": 657, "end_pos": 657, "uniprot_canonical_ac": "E0CZ42-1", "length": 1862, "uniprot_id": "FR1L6_MOUSE", "protein_name": "Fer-1-like protein 6", "refseq_ac": "", "refseq_name": "", "gene_name": "Fer1l6", "gene_names_uniprotkb": "Fer1l6", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E0CZ42", "url": "https://www.uniprot.org/uniprotkb/E0CZ42" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "DFITQSRVFISEAEKKPKTL", "down_seq": "QTALDKKRLTLCWQELKAMA", "glycosylation": [ { "glytoucan_ac": "G46691LC", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TLNQTALDK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn657", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "657", "end_pos": "657" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "E9Q573-1.282.282", "start_pos": 282, "end_pos": 282, "uniprot_canonical_ac": "E9Q573-1", "length": 300, "uniprot_id": "E9Q573_MOUSE", "protein_name": "CD200 molecule like 1", "refseq_ac": "NP_001005854", "refseq_name": "uncharacterized protein LOC208166", "gene_name": "Cd200l1", "gene_names_uniprotkb": "Cd200l1; Gm609", "gene_names_refseq": "Cd200l1; Gm1749; Gm609; iSEC2; isec1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "E9Q573", "url": "https://www.uniprot.org/uniprotkb/E9Q573" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NNMPEPSSTQMPNPLSTLVP", "down_seq": "PPSTETENLMRHHCQSET", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr282", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "282", "end_pos": "282" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q5NC55-1.280.280", "start_pos": 280, "end_pos": 280, "uniprot_canonical_ac": "Q5NC55-1", "length": 308, "uniprot_id": "Q5NC55_MOUSE", "protein_name": "Olfactory receptor", "refseq_ac": "NP_666747", "refseq_name": "olfactory receptor 313", "gene_name": "Or5af2", "gene_names_uniprotkb": "Or5af2; Olfr313", "gene_names_refseq": "MOR222-2; Olfr313; Or5af2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5NC55", "url": "https://www.uniprot.org/uniprotkb/Q5NC55" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PASQYSPTLGPLASIFYSVV", "down_seq": "PSLNPVVYCLRNKDMKFALQ", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "280", "end_pos": "280" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "A0A1W2P7S8-1.438.438", "start_pos": 438, "end_pos": 438, "uniprot_canonical_ac": "A0A1W2P7S8-1", "length": 802, "uniprot_id": "A0A1W2P7S8_MOUSE", "protein_name": "Cell division cycle 5-like protein", "refseq_ac": "XP_036012049", "refseq_name": "cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "gene_names_uniprotkb": "Cdc5lrt1; Cdc5lrt4; Gm32717; Gm32802", "gene_names_refseq": "Cdc5lrt1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A1W2P7S8", "url": "https://www.uniprot.org/uniprotkb/A0A1W2P7S8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "NGAEGLTPRSGTTPKPVTNA", "down_seq": "PGRTPLRDKLHINPEDGMAD", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr438", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "438", "end_pos": "438" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B2RXE2-1.759.759", "start_pos": 759, "end_pos": 759, "uniprot_canonical_ac": "B2RXE2-1", "length": 898, "uniprot_id": "SL9A5_MOUSE", "protein_name": "Sodium/hydrogen exchanger 5", "refseq_ac": "NP_001074801", "refseq_name": "sodium/hydrogen exchanger 5 precursor", "gene_name": "Slc9a5", "gene_names_uniprotkb": "Slc9a5; Nhe5", "gene_names_refseq": "Gm696; NHE-5; Slc9a5", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B2RXE2", "url": "https://www.uniprot.org/uniprotkb/B2RXE2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3388986564", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388986564", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GKVSGSLEVCPSPRIIPPSP", "down_seq": "CAEKELPWKSGQGDLAVYVS", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr759", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "snv": [ { "evidence": [ { "id": "rs3388986564", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388986564" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (T->I).", "chr_id": "8", "chr_pos": "106094686", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T759", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "759", "end_pos": "759" } ] }, { "type": "snv", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "759", "end_pos": "759" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B2RXE2-1.225.225", "start_pos": 225, "end_pos": 225, "uniprot_canonical_ac": "B2RXE2-1", "length": 898, "uniprot_id": "SL9A5_MOUSE", "protein_name": "Sodium/hydrogen exchanger 5", "refseq_ac": "NP_001074801", "refseq_name": "sodium/hydrogen exchanger 5 precursor", "gene_name": "Slc9a5", "gene_names_uniprotkb": "Slc9a5; Nhe5", "gene_names_refseq": "Gm696; NHE-5; Slc9a5", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B2RXE2", "url": "https://www.uniprot.org/uniprotkb/B2RXE2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388986635", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388986635", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "LFIIIFGESLLNDAVTVVLY", "down_seq": "VCNSFVEMGSANVQATDYLK", "snv": [ { "evidence": [ { "id": "rs3388986635", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388986635" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KVC->NVC).", "chr_id": "8", "chr_pos": "106082114", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K225", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "759", "end_pos": "759" } ] }, { "type": "snv", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "759", "end_pos": "759" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "B2RXE2-1.669.669", "start_pos": 669, "end_pos": 669, "uniprot_canonical_ac": "B2RXE2-1", "length": 898, "uniprot_id": "SL9A5_MOUSE", "protein_name": "Sodium/hydrogen exchanger 5", "refseq_ac": "NP_001074801", "refseq_name": "sodium/hydrogen exchanger 5 precursor", "gene_name": "Slc9a5", "gene_names_uniprotkb": "Slc9a5; Nhe5", "gene_names_refseq": "Gm696; NHE-5; Slc9a5", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "B2RXE2", "url": "https://www.uniprot.org/uniprotkb/B2RXE2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389006494", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389006494", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "ESFKSTKHNICFTKSKPRPR", "down_seq": "TSHKKKDGVANPEATNGKPP", "snv": [ { "evidence": [ { "id": "rs3389006494", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389006494" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KTS->NTS).", "chr_id": "8", "chr_pos": "106090050", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K669", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "759", "end_pos": "759" } ] }, { "type": "snv", "site_list": [ { "start_pos": "225", "end_pos": "225" }, { "start_pos": "669", "end_pos": "669" }, { "start_pos": "759", "end_pos": "759" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q9JKE1-1.33.33", "start_pos": 33, "end_pos": 33, "uniprot_canonical_ac": "Q9JKE1-1", "length": 183, "uniprot_id": "TREM3_MOUSE", "protein_name": "Triggering receptor expressed on myeloid cells 3", "refseq_ac": "NP_067382", "refseq_name": "triggering receptor expressed on myeloid cells 3 precursor", "gene_name": "Trem3", "gene_names_uniprotkb": "Trem3", "gene_names_refseq": "TREM-3; Trem3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9JKE1", "url": "https://www.uniprot.org/uniprotkb/Q9JKE1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q9JKE1", "url": "https://www.uniprot.org/uniprotkb/Q9JKE1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CVSGLQAGDEEEHKCFLEGE", "down_seq": "LTLTCPYNIMLYSLSLKAWQ", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn33", "evidence": [ { "id": "Q9JKE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9JKE1#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "33", "end_pos": "33" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21995-1.101.101", "start_pos": 101, "end_pos": 101, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KPSHVELKCVYTATKDLNLM", "down_seq": "VTWKKDDEPLETTGDFNTTK", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DLNLMNVTWK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn101", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn101", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "upstream", "id": "P21995-1.118.118", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.118.118", "start_pos": 118, "end_pos": 118, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NLMNVTWKKDDEPLETTGDF", "down_seq": "TTKMGNTLTSQYRFIVFNSK", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G39471UU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "KDDEPLETTGDFNTTK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G74724QE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn118", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "P21995-1.101.101", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.191.191", "start_pos": 191, "end_pos": 191, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IAYVGDSTVLKCVCQDCLPL", "down_seq": "WTWYMGNETAQVPIDAHSNE", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn191", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P21995-1.198.198", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21995-1.198.198", "start_pos": 198, "end_pos": 198, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TVLKCVCQDCLPLNWTWYMG", "down_seq": "ETAQVPIDAHSNEKYIINGS", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn198", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P21995-1.191.191", "categories": [ "glycosylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P21995-1.216.216", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.216.216", "start_pos": 216, "end_pos": 216, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MGNETAQVPIDAHSNEKYII", "down_seq": "GSHANETRLKIKHLLEEDGG", "glycosylation": [ { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn216", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn216", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YIINGSHANETR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn216", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn216", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P21995-1.198.198", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "P21995-1.221.221", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 3 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 3 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.221.221", "start_pos": 221, "end_pos": 221, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "AQVPIDAHSNEKYIINGSHA", "down_seq": "ETRLKIKHLLEEDGGSYWCR", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YIINGSHANETR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn221", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn221", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P21995-1.216.216", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.55.55", "start_pos": 55, "end_pos": 55, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PTDPTFTSLPVREEMMAKYS", "down_seq": "LSLKSCNISVTEKSNVSVEE", "glycosylation": [ { "glytoucan_ac": "G06247RL", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "YSNLSLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn55", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn55", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "upstream", "id": "P21995-1.62.62", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P21995-1.70.70", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.62.62", "start_pos": 62, "end_pos": 62, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.", "journal": "Nature biotechnology", "date": "2009", "authors": "Wollscheid B, Bausch-Fluck D, Henderson C, O'Brien R, Bibel M, Schiess R, Aebersold R, Watts JD", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19349973", "url": "https://glygen.org/publication/PubMed/19349973", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SLPVREEMMAKYSNLSLKSC", "down_seq": "ISVTEKSNVSVEENVILEKP", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G31852PQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SCNISVTEK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G66538GV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn62", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19349973", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19349973" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 7, "direction": "downstream", "id": "P21995-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21995-1.70.70", "categories": [ "glycosylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "P21995-1.78.78", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.70.70", "start_pos": 70, "end_pos": 70, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] }, { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "reference": [ { "type": "PubMed", "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2281", "url": "https://glyconnect.expasy.org/browser/proteins/2281", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "19656770", "url": "https://glygen.org/publication/PubMed/19656770", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MAKYSNLSLKSCNISVTEKS", "down_seq": "VSVEENVILEKPSHVELKCV", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SNVSVEENVILEKPSHVELK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G14669DU", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G33609NS", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G66538GV", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "G84820NF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2281", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2281" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "P21995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21995#ptm_processing" }, { "id": "19656770", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/19656770" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P21995-1.55.55", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21995-1.62.62", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "upstream", "id": "P21995-1.78.78", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 11 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 10 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 10 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 10 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 10 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 10 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "P21995", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P21995" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] } ], "crossref": [ { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P21995", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P21995", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "P21995", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P21995" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21995-1.78.78", "start_pos": 78, "end_pos": 78, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs30541012", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30541012", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "I", "start_aa": "I", "up_seq": "LKSCNISVTEKSNVSVEENV", "down_seq": "LEKPSHVELKCVYTATKDLN", "snv": [ { "evidence": [ { "id": "rs30541012", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs30541012" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "I", "sequence_mut": "S", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NVI->NVS).", "chr_id": "13", "chr_pos": "117385841", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "I78", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P21995-1.62.62", "categories": [ "glycosylation_flag" ] }, { "distance": 8, "direction": "downstream", "id": "P21995-1.70.70", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21995-1.312.312", "start_pos": 312, "end_pos": 312, "uniprot_canonical_ac": "P21995-1", "length": 330, "uniprot_id": "EMB_MOUSE", "protein_name": "Embigin", "refseq_ac": "NP_034460", "refseq_name": "embigin precursor", "gene_name": "Emb", "gene_names_uniprotkb": "Emb; Gp70", "gene_names_refseq": "Emb; Gp70", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KNDPDAGKEFEQIEQLKSDD", "down_seq": "NGIENNVPRYRKTDSADQ", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21995", "url": "https://www.uniprot.org/uniprotkb/P21995" } ], "site_lbl": "Ser312" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "101", "end_pos": "101" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "191", "end_pos": "191" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "216", "end_pos": "216" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "55", "end_pos": "55" }, { "start_pos": "62", "end_pos": "62" }, { "start_pos": "70", "end_pos": "70" } ] }, { "type": "snv", "site_list": [ { "start_pos": "78", "end_pos": "78" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "312", "end_pos": "312" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P52793-1.26.26", "start_pos": 26, "end_pos": 26, "uniprot_canonical_ac": "P52793-1", "length": 205, "uniprot_id": "EFNA1_MOUSE", "protein_name": "Ephrin-A1", "refseq_ac": "NP_034237", "refseq_name": "ephrin-A1 isoform 1 precursor", "gene_name": "Efna1", "gene_names_uniprotkb": "Efna1; Epgl1; Epl1; Lerk1", "gene_names_refseq": "B61; Efl1; Efna1; Epl1; Eplg1; Lerk1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52793", "url": "https://www.uniprot.org/uniprotkb/P52793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2290", "url": "https://glyconnect.expasy.org/browser/proteins/2290" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2290", "url": "https://glyconnect.expasy.org/browser/proteins/2290", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P52793", "url": "https://www.uniprot.org/uniprotkb/P52793", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "APLLGLCCSLAAADRHIVFW", "down_seq": "SSNPKFREEDYTVHVQLNDY", "glycosylation": [ { "glytoucan_ac": "G06110VR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2290", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2290" } ] }, { "glytoucan_ac": "G50045TK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2290", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2290" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2290", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2290" } ] }, { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "HIVFWNSSNPK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G82119TF", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2290", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2290" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn26", "evidence": [ { "id": "P52793", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52793#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "26", "end_pos": "26" } ] }, { "type": "snv", "site_list": [ { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 5 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 5 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P52793-1.95.95", "start_pos": 95, "end_pos": 95, "uniprot_canonical_ac": "P52793-1", "length": 205, "uniprot_id": "EFNA1_MOUSE", "protein_name": "Ephrin-A1", "refseq_ac": "NP_034237", "refseq_name": "ephrin-A1 isoform 1 precursor", "gene_name": "Efna1", "gene_names_uniprotkb": "Efna1; Epgl1; Epl1; Lerk1", "gene_names_refseq": "B61; Efl1; Efna1; Epl1; Eplg1; Lerk1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P52793", "url": "https://www.uniprot.org/uniprotkb/P52793" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388638221", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388638221", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "QEYVACQPQSKDQVRWNCNR", "down_seq": "SAKHGPEKLSEKFQRFTPFI", "snv": [ { "evidence": [ { "id": "rs3388638221", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388638221" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NRP->NRT).", "chr_id": "3", "chr_pos": "89183542", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P95", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "26", "end_pos": "26" } ] }, { "type": "snv", "site_list": [ { "start_pos": "95", "end_pos": "95" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70372-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.", "journal": "PloS one", "date": "2014", "authors": "Gurel Z, Zaro BW, Pratt MR, Sheibani N", "evidence": [ { "database": "O-GlcNAc Database", "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" } ], "reference": [ { "type": "PubMed", "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70372", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24788674", "url": "https://glygen.org/publication/PubMed/24788674", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "P70372", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P70372" }, { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "24788674", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24788674" } ] } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "upstream", "id": "P70372-1.2.2", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70372-1.100.100", "start_pos": 100, "end_pos": 100, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function.", "journal": "Nucleic acids research", "date": "2011", "authors": "Yu TX, Wang PY, Rao JN, Zou T, Liu L, Xiao L, Gorospe M, Wang JY", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "reference": [ { "type": "PubMed", "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814" } ] } ], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "TLNGLRLQSKTIKVSYARPS", "down_seq": "EVIKDANLYISGLPRTMTQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" }, { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" }, { "database": "PubMed", "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814" } ], "site_lbl": "Ser100" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "P70372-1.88.88", "categories": [ "phosphorylation_flag" ] }, { "distance": 18, "direction": "upstream", "id": "P70372-1.118.118", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70372-1.118.118", "start_pos": 118, "end_pos": 118, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function.", "journal": "Nucleic acids research", "date": "2011", "authors": "Yu TX, Wang PY, Rao JN, Zou T, Liu L, Xiao L, Gorospe M, Wang JY", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "reference": [ { "type": "PubMed", "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814" } ] }, { "title": "[Post-transcriptional regulation of dual-specificity phosphatase-1 by RNA-binding protein HuR T118 in heat shock].", "journal": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University", "date": "2014", "authors": "Zhang C, Luo H, Jiang Y", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "reference": [ { "type": "PubMed", "id": "24968827", "url": "https://glygen.org/publication/PubMed/24968827" } ] } ], "crossref": [ { "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814", "database": "PubMed", "categories": [ "Other" ] }, { "id": "24968827", "url": "https://glygen.org/publication/PubMed/24968827", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PSSEVIKDANLYISGLPRTM", "down_seq": "QKDVEDMFSRFGRIINSRVL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" }, { "database": "PubMed", "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814" }, { "database": "PubMed", "id": "24968827", "url": "https://glygen.org/publication/PubMed/24968827" } ], "site_lbl": "Thr118" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P70372-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70372-1.158.158", "start_pos": 158, "end_pos": 158, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LVDQTTGLSRGVAFIRFDKR", "down_seq": "EAEEAITSFNGHKPPGSSEP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "site_lbl": "Ser158" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70372-1.197.197", "start_pos": 197, "end_pos": 197, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPITVKFAANPNQNKNMALL", "down_seq": "QLYHSPARRFGGPVHHQAQR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "site_lbl": "Ser197" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "upstream", "id": "P70372-1.202.202", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70372-1.202.202", "start_pos": 202, "end_pos": 202, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" }, { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KFAANPNQNKNMALLSQLYH", "down_seq": "PARRFGGPVHHQAQRFRFSP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "site_lbl": "Ser202" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 5, "direction": "downstream", "id": "P70372-1.197.197", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P70372-1.221.221", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70372-1.221.221", "start_pos": 221, "end_pos": 221, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease.", "journal": "Scientific reports", "date": "2017", "authors": "Sasaki Y, Dehnad A, Fish S, Sato A, Jiang J, Tian J, Schroder K, Brandes R, Torok NJ", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "reference": [ { "type": "PubMed", "id": "28383062", "url": "https://glygen.org/publication/PubMed/28383062" } ] } ], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "28383062", "url": "https://glygen.org/publication/PubMed/28383062", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "HSPARRFGGPVHHQAQRFRF", "down_seq": "PMGVDHMSGISGVNVPGNAS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" }, { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" }, { "database": "PubMed", "id": "28383062", "url": "https://glygen.org/publication/PubMed/28383062" } ], "site_lbl": "Ser221" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P70372-1.202.202", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P70372-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "NGYEDHMAEDCRDDIGRTNL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 2, "direction": "downstream", "id": "P70372-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70372-1.318.318", "start_pos": 318, "end_pos": 318, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "AAMAIASLNGYRLGDKILQV", "down_seq": "FKTNKSHK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "site_lbl": "Ser318" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P70372-1.88.88", "start_pos": 88, "end_pos": 88, "uniprot_canonical_ac": "P70372-1", "length": 326, "uniprot_id": "ELAV1_MOUSE", "protein_name": "ELAV-like protein 1", "refseq_ac": "NP_034615", "refseq_name": "ELAV-like protein 1", "gene_name": "Elavl1", "gene_names_uniprotkb": "Elavl1; Elra; Hua", "gene_names_refseq": "2410055N02Rik; Elavl1; HUR; Hua", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P70372", "url": "https://www.uniprot.org/uniprotkb/P70372" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function.", "journal": "Nucleic acids research", "date": "2011", "authors": "Yu TX, Wang PY, Rao JN, Zou T, Liu L, Xiao L, Gorospe M, Wang JY", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" } ], "reference": [ { "type": "PubMed", "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814" } ] } ], "crossref": [ { "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "YVTAKDAERAISTLNGLRLQ", "down_seq": "KTIKVSYARPSSEVIKDANL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P70372", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P70372" }, { "database": "PubMed", "id": "21745814", "url": "https://glygen.org/publication/PubMed/21745814" } ], "site_lbl": "Ser88" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "100", "end_pos": "100" }, { "start_pos": "118", "end_pos": "118" }, { "start_pos": "158", "end_pos": "158" }, { "start_pos": "197", "end_pos": "197" }, { "start_pos": "202", "end_pos": "202" }, { "start_pos": "221", "end_pos": "221" }, { "start_pos": "2", "end_pos": "2" }, { "start_pos": "318", "end_pos": "318" }, { "start_pos": "88", "end_pos": "88" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "upstream", "id": "P70372-1.100.100", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CBF3-1.334.334", "start_pos": 334, "end_pos": 334, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PPEVACTSVPSGPRNVISIV", "down_seq": "ETSIILEWHPPRETGGRDDV", "glycosylation": [ { "glytoucan_ac": "G07755XJ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NVISIVNETSIILEWHPPR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn334", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn334", "evidence": [ { "id": "Q8CBF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CBF3-1.426.426", "start_pos": 426, "end_pos": 426, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IQAINGVSSKSPFPPQHVSV", "down_seq": "ITTNQAAPSTVPIMHQVSAT", "glycosylation": [ { "glytoucan_ac": "G02815KT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SPFPPQHVSVNITTNQAAPSTVPIMHQVSATMR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn426", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn426", "evidence": [ { "id": "Q8CBF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CBF3-1.480.480", "start_pos": 480, "end_pos": 480, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "rs3389075562", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389075562", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PNGIILDYEIRYYEKEHNEF", "down_seq": "SSMARSQTNTARIDGLRPGM", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "EHNEFNSSMAR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn480", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn480", "evidence": [ { "id": "Q8CBF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3#ptm_processing" } ] } ], "snv": [ { "evidence": [ { "id": "rs3389075562", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389075562" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "K", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NSS->KSS).", "chr_id": "9", "chr_pos": "101879049", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N480", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CBF3-1.977.977", "start_pos": 977, "end_pos": 977, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TLAGHQKKILSSIHSMRVQM", "down_seq": "QSPSVMA", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VQMNQSPSVMA", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn977", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CBF3-1.516.516", "start_pos": 516, "end_pos": 516, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389067692", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389067692", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "LRPGMVYVVQVRARTVAGYG", "down_seq": "FSGKMCFQTLTDDDYKSELR", "snv": [ { "evidence": [ { "id": "rs3389067692", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389067692" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "K", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (KFS->NFS).", "chr_id": "9", "chr_pos": "101878941", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "K516", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8CBF3-1.600.600", "start_pos": 600, "end_pos": 600, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis.", "journal": "Molecular biology of the cell", "date": "2020-05-15", "authors": "Tiruppathi Chinnaswamy, Regmi Sushil C, Wang Dong-Mei, Mo Gary C H, Toth Peter T, Vogel Stephen M, Stan Radu V, Henkemeyer Mark, Minshall Richard D, Rehman Jalees, Malik Asrar B", "evidence": [ { "database": "iPTMnet", "id": "Q8CBF3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CBF3" } ], "reference": [ { "type": "PubMed", "id": "32238105", "url": "https://glygen.org/publication/PubMed/32238105" } ] } ], "crossref": [ { "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8CBF3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CBF3", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32238105", "url": "https://glygen.org/publication/PubMed/32238105", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "QHYSTGRGSPGMKIYIDPFT", "down_seq": "EDPNEAVREFAKEIDVSFVK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" }, { "database": "iPTMnet", "id": "Q8CBF3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8CBF3" }, { "database": "PubMed", "id": "32238105", "url": "https://glygen.org/publication/PubMed/32238105" } ], "site_lbl": "Tyr600" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CBF3-1.928.928", "start_pos": 928, "end_pos": 928, "uniprot_canonical_ac": "Q8CBF3-1", "length": 984, "uniprot_id": "EPHB1_MOUSE", "protein_name": "Ephrin type-B receptor 1", "refseq_ac": "NP_001161768", "refseq_name": "ephrin type-B receptor 1 isoform 2 precursor", "gene_name": "Ephb1", "gene_names_uniprotkb": "Ephb1", "gene_names_refseq": "9330129L11; C130099E04Rik; Cek6; Elkh; Elk; Ephb1; Hek6; Net", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "Y", "start_aa": "Y", "up_seq": "PDFTAFTTVDDWLSAIKMVQ", "down_seq": "RDSFLTAGFTSLQLVTQMTS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q8CBF3", "url": "https://www.uniprot.org/uniprotkb/Q8CBF3" } ], "site_lbl": "Tyr928" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "334", "end_pos": "334" }, { "start_pos": "426", "end_pos": "426" }, { "start_pos": "480", "end_pos": "480" }, { "start_pos": "977", "end_pos": "977" } ] }, { "type": "snv", "site_list": [ { "start_pos": "480", "end_pos": "480" }, { "start_pos": "516", "end_pos": "516" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "600", "end_pos": "600" }, { "start_pos": "928", "end_pos": "928" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "C0HKE2-1.121.121", "start_pos": 121, "end_pos": 121, "uniprot_canonical_ac": "C0HKE2-1", "length": 130, "uniprot_id": "H2A1C_MOUSE", "protein_name": "Histone H2A type 1-C", "refseq_ac": "NP_835496", "refseq_name": "histone H2A type 1-C", "gene_name": "H2ac6", "gene_names_uniprotkb": "H2ac6; Hist1h2ac", "gene_names_refseq": "H2ac6; Hist1h2ac", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "VTIAQGGVLPNIQAVLLPKK", "down_seq": "ESHHKAKGK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by DCAF1", "evidence": [ { "database": "UniProtKB", "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2" } ], "site_lbl": "Thr121" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "121", "end_pos": "121" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "C0HKE2-1.2.2", "start_pos": 2, "end_pos": 2, "uniprot_canonical_ac": "C0HKE2-1", "length": 130, "uniprot_id": "H2A1C_MOUSE", "protein_name": "Histone H2A type 1-C", "refseq_ac": "NP_835496", "refseq_name": "histone H2A type 1-C", "gene_name": "H2ac6", "gene_names_uniprotkb": "H2ac6; Hist1h2ac", "gene_names_refseq": "H2ac6; Hist1h2ac", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Quantitative determination of histone modification. H2A acetylation and phosphorylation.", "journal": "The Journal of biological chemistry", "date": "1981", "authors": "Pantazis P, Bonner WM", "evidence": [ { "database": "UniProtKB", "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2" }, { "database": "iPTMnet", "id": "C0HKE2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/C0HKE2" } ], "reference": [ { "type": "PubMed", "id": "7217105", "url": "https://glygen.org/publication/PubMed/7217105" } ] } ], "crossref": [ { "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "C0HKE2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/C0HKE2", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "7217105", "url": "https://glygen.org/publication/PubMed/7217105", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "M", "down_seq": "GRGKQGGKARAKAKTRSSRA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by RPS6KA5", "evidence": [ { "database": "UniProtKB", "id": "C0HKE2", "url": "https://www.uniprot.org/uniprotkb/C0HKE2" }, { "database": "iPTMnet", "id": "C0HKE2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/C0HKE2" }, { "database": "PubMed", "id": "7217105", "url": "https://glygen.org/publication/PubMed/7217105" } ], "site_lbl": "Ser2" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "121", "end_pos": "121" }, { "start_pos": "2", "end_pos": "2" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.113.113", "start_pos": 113, "end_pos": 113, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VGVDGAIKALCNRLVVVELN", "down_seq": "RTSRDLAEQCVKVLELICTR", "glycosylation": [ { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LVVVELNNR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn113", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1347.1347", "start_pos": 1347, "end_pos": 1347, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" }, { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YRMGAEGKFDLKLAPGYDPD", "down_seq": "VASPKPVSSTVSGTTQSWSS", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1347", "evidence": [ { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "Q69ZR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q69ZR2-1.1350.1350", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 8, "direction": "upstream", "id": "Q69ZR2-1.1355.1355", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q69ZR2-1.1356.1356", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q69ZR2-1.1359.1359", "categories": [ "glycosylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "Q69ZR2-1.1361.1361", "categories": [ "glycosylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q69ZR2-1.1362.1362", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1350.1350", "start_pos": 1350, "end_pos": 1350, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "rs3403278558", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3403278558", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "GAEGKFDLKLAPGYDPDTVA", "down_seq": "PKPVSSTVSGTTQSWSSLVK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1350", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "snv": [ { "evidence": [ { "id": "rs3403278558", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3403278558" } ], "glycoeffect": [ "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: o-glyco-site-loss (S->*).", "chr_id": "12", "chr_pos": "51816022", "ref_nt": "C", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S1350", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q69ZR2-1.1347.1347", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q69ZR2-1.1355.1355", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q69ZR2-1.1356.1356", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q69ZR2-1.1359.1359", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q69ZR2-1.1361.1361", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "Q69ZR2-1.1362.1362", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1355.1355", "start_pos": 1355, "end_pos": 1355, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network.", "journal": "Angewandte Chemie (International ed. in English)", "date": "2023-02-27", "authors": "Hao Yi, Li Xiang, Qin Ke, Shi Yujie, He Yanwen, Zhang Che, Cheng Bo, Zhang Xiwen, Hu Guangyu, Liang Shuyu, Tang Qi, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" }, { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467" } ] }, { "title": "O-GlcNAcylation of nuclear proteins in the mouse liver exhibit daily oscillations that are influenced by meal timing.", "journal": "PLoS biology", "date": "2025-09", "authors": "Liu Xianhui, Cai Yao D, Hou Chunyan, Liu Xu, Luo Youcheng, Mendiola Aron Judd P, Xu Xuehan, Luo Yige, Zheng Haiyan, Zhao Caifeng, Chen Ching-Hsuan, Zhang Yong, Xiang Yang K, Ma Junfeng, Chiu Joanna C", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131" } ] }, { "title": "Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model.", "journal": "Molecular medicine (Cambridge, Mass.)", "date": "2025-02-28", "authors": "Hao Yi, Li Zhongzhong, Du Xinyan, Xie Qingsong, Li Dongxiao, Lei Shaoyuan, Guo Yansu", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952" } ] }, { "title": "Comprehensive Evaluation of Cleavable Bioorthogonal Probes for Site-Specific O-GlcNAc Proteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-10", "authors": "Hou Chunyan, Zhang Hemeng, Deng Jingtao, Wang Xiaoxin, Byers Stephen, Levi Moshe, Pak Daniel T S, Moremen Kelley W, Pei Huadong, Hart Gerald W, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482" } ] }, { "title": "Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Alfaro JF, Gong CX, Monroe ME, Aldrich JT, Clauss TR, Purvine SO, Wang Z, Camp DG 2nd, Shabanowitz J, Stanley P, Hart GW, Hunt DF, Yang F, Smith RD", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741" } ] }, { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36852467", "url": "https://glygen.org/publication/PubMed/36852467", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40997131", "url": "https://glygen.org/publication/PubMed/40997131", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40021952", "url": "https://glygen.org/publication/PubMed/40021952", "database": "PubMed", "categories": [ "Other" ] }, { "id": "40885482", "url": "https://glygen.org/publication/PubMed/40885482", "database": "PubMed", "categories": [ "Other" ] }, { "id": "22517741", "url": "https://glygen.org/publication/PubMed/22517741", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FDLKLAPGYDPDTVASPKPV", "down_seq": "STVSGTTQSWSSLVKNNCPD", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1355", "evidence": [ { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "Q69ZR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" }, { "id": "36852467", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36852467" }, { "id": "40997131", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40997131" }, { "id": "40021952", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40021952" }, { "id": "40885482", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40885482" }, { "id": "22517741", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22517741" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" }, { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q69ZR2-1.1347.1347", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q69ZR2-1.1350.1350", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q69ZR2-1.1356.1356", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q69ZR2-1.1359.1359", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q69ZR2-1.1361.1361", "categories": [ "glycosylation_flag" ] }, { "distance": 7, "direction": "upstream", "id": "Q69ZR2-1.1362.1362", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1356.1356", "start_pos": 1356, "end_pos": 1356, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DLKLAPGYDPDTVASPKPVS", "down_seq": "TVSGTTQSWSSLVKNNCPDK", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1356", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q69ZR2-1.1347.1347", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q69ZR2-1.1350.1350", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q69ZR2-1.1355.1355", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q69ZR2-1.1359.1359", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "upstream", "id": "Q69ZR2-1.1361.1361", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "Q69ZR2-1.1362.1362", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1359.1359", "start_pos": 1359, "end_pos": 1359, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LAPGYDPDTVASPKPVSSTV", "down_seq": "GTTQSWSSLVKNNCPDKTSA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1359", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 12, "direction": "downstream", "id": "Q69ZR2-1.1347.1347", "categories": [ "glycosylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q69ZR2-1.1350.1350", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q69ZR2-1.1355.1355", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q69ZR2-1.1356.1356", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q69ZR2-1.1361.1361", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "Q69ZR2-1.1362.1362", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1361.1361", "start_pos": 1361, "end_pos": 1361, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "PGYDPDTVASPKPVSSTVSG", "down_seq": "TQSWSSLVKNNCPDKTSAAA", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1361", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 14, "direction": "downstream", "id": "Q69ZR2-1.1347.1347", "categories": [ "glycosylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q69ZR2-1.1350.1350", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q69ZR2-1.1355.1355", "categories": [ "glycosylation_flag" ] }, { "distance": 5, "direction": "downstream", "id": "Q69ZR2-1.1356.1356", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q69ZR2-1.1359.1359", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "upstream", "id": "Q69ZR2-1.1362.1362", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1362.1362", "start_pos": 1362, "end_pos": 1362, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Cytosolic N-GlcNAc proteins are formed by the action of endo-beta-N-acetylglucosaminidase.", "journal": "Biochemical and biophysical research communications", "date": "2020", "authors": "Maynard JC, Fujihira H, Dolgonos GE, Suzuki T, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141" } ] } ], "crossref": [ { "id": "32782141", "url": "https://glygen.org/publication/PubMed/32782141", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://oglcnac.org/atlas/detail/Q69ZR2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "GYDPDTVASPKPVSSTVSGT", "down_seq": "QSWSSLVKNNCPDKTSAAAG", "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1362", "evidence": [ { "id": "32782141", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/32782141" }, { "id": "Q69ZR2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q69ZR2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q69ZR2-1.1347.1347", "categories": [ "glycosylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "Q69ZR2-1.1350.1350", "categories": [ "glycosylation_flag", "snv_flag" ] }, { "distance": 7, "direction": "downstream", "id": "Q69ZR2-1.1355.1355", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q69ZR2-1.1356.1356", "categories": [ "glycosylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "Q69ZR2-1.1359.1359", "categories": [ "glycosylation_flag" ] }, { "distance": 1, "direction": "downstream", "id": "Q69ZR2-1.1361.1361", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1564.1564", "start_pos": 1564, "end_pos": 1564, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "SRETSSLESFVRRVANIART", "down_seq": "ATNNMNLSRSSSDNNTNTLG", "glycosylation": [ { "glytoucan_ac": "G46503DX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "VANIARTNATNNMNLSR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1564", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "upstream", "id": "Q69ZR2-1.1572.1572", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1983.1983", "start_pos": 1983, "end_pos": 1983, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "GTKSGLNQGAISSLQSSDIL", "down_seq": "LTKEQPQAKAGNGQSPCGVE", "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "SGLNQGAISSLQSSDILNLTK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1983", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.689.689", "start_pos": 689, "end_pos": 689, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "IIRGRDCLYIWSDAAALELS", "down_seq": "GSNGWFRFILDGKLATMYSS", "glycosylation": [ { "glytoucan_ac": "G59924QI", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "GRDCLYIWSDAAALELSNGSNGWFR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn689", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "Q69ZR2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q69ZR2" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.2587.2587", "start_pos": 2587, "end_pos": 2587, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme.", "journal": "The Journal of cell biology", "date": "2012", "authors": "Sarkar AA, Zohn IE", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "22431752", "url": "https://glygen.org/publication/PubMed/22431752" } ] } ], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "22431752", "url": "https://glygen.org/publication/PubMed/22431752", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "C", "start_aa": "C", "up_seq": "RLTVVRKVDATDASYPSVNT", "down_seq": "VHYLKLPEYSSEEIMRERLL", "mutagenesis": [ { "sequence_org": "C", "sequence_mut": "G", "comment": "Loss of activity. No effect on binding to HSP90AA1.", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "PubMed", "id": "22431752", "url": "https://glygen.org/publication/PubMed/22431752" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1389.1389", "start_pos": 1389, "end_pos": 1389, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "iPTMnet", "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VKNNCPDKTSAAAGSSSRKG", "down_seq": "SSSVCSVASSSDISLASTKT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2" } ], "site_lbl": "Ser1389" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1493.1493", "start_pos": 1493, "end_pos": 1493, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SSVRAPGESSAISMGIVSVS", "down_seq": "PDVSSVSELTNKEAASQRPL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "site_lbl": "Ser1493" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q69ZR2-1.1572.1572", "start_pos": 1572, "end_pos": 1572, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "iPTMnet", "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "SFVRRVANIARTNATNNMNL", "down_seq": "RSSSDNNTNTLGRNVMSTAT", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2" } ], "site_lbl": "Ser1572" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q69ZR2-1.1564.1564", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q69ZR2-1.1777.1777", "start_pos": 1777, "end_pos": 1777, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ETKGGRRRAWDDDYVLKRQF", "down_seq": "ALVPAFDPRPGRTNVQQTTD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "site_lbl": "Ser1777" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q69ZR2-1.2323.2323", "start_pos": 2323, "end_pos": 2323, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CTESQSEASTEEGHDSLSVG", "down_seq": "FEEDSKSEFILDPPKPKPPA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "site_lbl": "Ser2323" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q69ZR2-1.632.632", "start_pos": 632, "end_pos": 632, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "FLDQLARLGVISKVSALAGP", "down_seq": "SDDENEEESKPEKEDEPQED", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "site_lbl": "Ser632" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "upstream", "id": "Q69ZR2-1.641.641", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q69ZR2-1.641.641", "start_pos": 641, "end_pos": 641, "uniprot_canonical_ac": "Q69ZR2-1", "length": 2618, "uniprot_id": "HECD1_MOUSE", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "refseq_ac": "", "refseq_name": "", "gene_name": "Hectd1", "gene_names_uniprotkb": "Hectd1; Kiaa1131; Opm", "gene_names_refseq": "", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "iPTMnet", "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "VISKVSALAGPSSDDENEEE", "down_seq": "KPEKEDEPQEDAKELQQGKP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q69ZR2", "url": "https://www.uniprot.org/uniprotkb/Q69ZR2" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q69ZR2", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q69ZR2" } ], "site_lbl": "Ser641" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" }, { "start_pos": "1347", "end_pos": "1347" }, { "start_pos": "1350", "end_pos": "1350" }, { "start_pos": "1355", "end_pos": "1355" }, { "start_pos": "1356", "end_pos": "1356" }, { "start_pos": "1359", "end_pos": "1359" }, { "start_pos": "1361", "end_pos": "1361" }, { "start_pos": "1362", "end_pos": "1362" }, { "start_pos": "1564", "end_pos": "1564" }, { "start_pos": "1983", "end_pos": "1983" }, { "start_pos": "689", "end_pos": "689" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "2587", "end_pos": "2587" } ] }, { "type": "snv", "site_list": [ { "start_pos": "1350", "end_pos": "1350" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "1389", "end_pos": "1389" }, { "start_pos": "1493", "end_pos": "1493" }, { "start_pos": "1572", "end_pos": "1572" }, { "start_pos": "1777", "end_pos": "1777" }, { "start_pos": "2323", "end_pos": "2323" }, { "start_pos": "632", "end_pos": "632" }, { "start_pos": "641", "end_pos": "641" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 9, "direction": "downstream", "id": "Q69ZR2-1.632.632", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21729-1.191.191", "start_pos": 191, "end_pos": 191, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Glycosylation of the gastrin-releasing peptide receptor and its effect on expression, G protein coupling, and receptor modulatory processes.", "journal": "Molecular pharmacology", "date": "2000", "authors": "Benya RV, Kusui T, Katsuno T, Tsuda T, Mantey SA, Battey JF, Jensen RT", "evidence": [ { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789" } ] } ], "crossref": [ { "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "LLAIPEAVFSDLHPFHVKDT", "down_seq": "QTFISCAPYPHSNELHPKIH", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn191", "evidence": [ { "id": "11093789", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11093789" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "RLIMS-G_1.0;GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "RLIMS-G_1.0" }, { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21729-1.20.20", "start_pos": 20, "end_pos": 20, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Glycosylation of the gastrin-releasing peptide receptor and its effect on expression, G protein coupling, and receptor modulatory processes.", "journal": "Molecular pharmacology", "date": "2000", "authors": "Benya RV, Kusui T, Katsuno T, Tsuda T, Mantey SA, Battey JF, Jensen RT", "evidence": [ { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789" } ] } ], "crossref": [ { "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "", "down_seq": "DTFNQSLSPPKMDNWFHPGF", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true, "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn20", "evidence": [ { "id": "P21729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21729#ptm_processing" }, { "id": "11093789", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11093789" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "RLIMS-G_1.0;GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "RLIMS-G_1.0" }, { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P21729-1.5.5", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P21729-1.24.24", "categories": [ "glycosylation_flag" ] }, { "distance": 6, "direction": "upstream", "id": "P21729-1.26.26", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21729-1.24.24", "start_pos": 24, "end_pos": 24, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Glycosylation of the gastrin-releasing peptide receptor and its effect on expression, G protein coupling, and receptor modulatory processes.", "journal": "Molecular pharmacology", "date": "2000", "authors": "Benya RV, Kusui T, Katsuno T, Tsuda T, Mantey SA, Battey JF, Jensen RT", "evidence": [ { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789" } ] } ], "crossref": [ { "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "NNCSHLNLDVDPFLSCNDTF", "down_seq": "QSLSPPKMDNWFHPGFIYVI", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true, "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn24", "evidence": [ { "id": "P21729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21729#ptm_processing" }, { "id": "11093789", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11093789" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "RLIMS-G_1.0;GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "RLIMS-G_1.0" }, { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 19, "direction": "downstream", "id": "P21729-1.5.5", "categories": [ "glycosylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P21729-1.20.20", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P21729-1.26.26", "categories": [ "snv_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21729-1.5.5", "start_pos": 5, "end_pos": 5, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Glycosylation of the gastrin-releasing peptide receptor and its effect on expression, G protein coupling, and receptor modulatory processes.", "journal": "Molecular pharmacology", "date": "2000", "authors": "Benya RV, Kusui T, Katsuno T, Tsuda T, Mantey SA, Battey JF, Jensen RT", "evidence": [ { "database": "GlyGen", "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492" } ], "reference": [ { "type": "PubMed", "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789" } ] } ], "crossref": [ { "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "11093789", "url": "https://glygen.org/publication/PubMed/11093789", "database": "PubMed", "categories": [ "Other" ] }, { "id": "GLY_000492", "url": "https://data.glygen.org/GLY_000492", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "MAPN", "down_seq": "CSHLNLDVDPFLSCNDTFNQ", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true, "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn5", "evidence": [ { "id": "P21729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21729#ptm_processing" }, { "id": "11093789", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/11093789" }, { "id": "GLY_000492", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000492" } ], "mining_tool": "RLIMS-G_1.0;GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "RLIMS-G_1.0" }, { "label": "GlycoSiteMiner_1.0" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P21729-1.20.20", "categories": [ "glycosylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "P21729-1.24.24", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P21729-1.26.26", "start_pos": 26, "end_pos": 26, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3389540529", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389540529", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "CSHLNLDVDPFLSCNDTFNQ", "down_seq": "LSPPKMDNWFHPGFIYVIPA", "snv": [ { "evidence": [ { "id": "rs3389540529", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389540529" } ], "glycoeffect": [ "n-glyco-sequon-loss", "o-glyco-site-loss" ], "sequence_org": "S", "sequence_mut": "R", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NQS->NQR).", "chr_id": "X", "chr_pos": "162332218", "ref_nt": "G", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "S26", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 6, "direction": "downstream", "id": "P21729-1.20.20", "categories": [ "glycosylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P21729-1.24.24", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21729-1.367.367", "start_pos": 367, "end_pos": 367, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3412493404", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412493404", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "P", "start_aa": "P", "up_seq": "NRSHSTGRSTTCMTSFKSTN", "down_seq": "SATFSLINRNICHEGYV", "snv": [ { "evidence": [ { "id": "rs3412493404", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3412493404" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "P", "sequence_mut": "T", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (NPS->NTS).", "chr_id": "X", "chr_pos": "162297944", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "P367", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "P21729-1.351.351", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P21729-1.351.351", "start_pos": 351, "end_pos": 351, "uniprot_canonical_ac": "P21729-1", "length": 384, "uniprot_id": "GRPR_MOUSE", "protein_name": "Gastrin-releasing peptide receptor", "refseq_ac": "NP_032203", "refseq_name": "gastrin-releasing peptide receptor", "gene_name": "Grpr", "gene_names_uniprotkb": "Grpr", "gene_names_refseq": "GRP-R; Grpr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RKQFNTQLLCCQPGLMNRSH", "down_seq": "TGRSTTCMTSFKSTNPSATF", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P21729", "url": "https://www.uniprot.org/uniprotkb/P21729" } ], "site_lbl": "Ser351" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "191", "end_pos": "191" }, { "start_pos": "20", "end_pos": "20" }, { "start_pos": "24", "end_pos": "24" }, { "start_pos": "5", "end_pos": "5" } ] }, { "type": "snv", "site_list": [ { "start_pos": "26", "end_pos": "26" }, { "start_pos": "367", "end_pos": "367" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "upstream", "id": "P21729-1.367.367", "categories": [ "snv_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P47791-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "P47791-1", "length": 500, "uniprot_id": "GSHR_MOUSE", "protein_name": "Glutathione reductase, mitochondrial", "refseq_ac": "NP_034474", "refseq_name": "glutathione reductase, mitochondrial precursor", "gene_name": "Gsr", "gene_names_uniprotkb": "Gsr; Gr1", "gene_names_refseq": "D8Ertd238e; Gr-1; Gr1; Gsr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P47791", "url": "https://www.uniprot.org/uniprotkb/P47791" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "rs3398908333", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3398908333", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "TSLMIRHDKVLRNFDSLISS", "down_seq": "CTEELENAGVEVLKFTQVKE", "glycosylation": [ { "glytoucan_ac": "G09831WQ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NFDSLISSNCTEELENAGVEVLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn255", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "snv": [ { "evidence": [ { "id": "rs3398908333", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3398908333" } ], "glycoeffect": [ "n-glyco-sequon-loss" ], "sequence_org": "N", "sequence_mut": "I", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-loss (NCT->ICT).", "chr_id": "8", "chr_pos": "34172655", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "N255", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "297", "end_pos": "297" } ] } ], "categories": [ "glycosylation_flag", "snv_flag" ], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P47791-1.433.433", "start_pos": 433, "end_pos": 433, "uniprot_canonical_ac": "P47791-1", "length": 500, "uniprot_id": "GSHR_MOUSE", "protein_name": "Glutathione reductase, mitochondrial", "refseq_ac": "NP_034474", "refseq_name": "glutathione reductase, mitochondrial precursor", "gene_name": "Gsr", "gene_names_uniprotkb": "Gsr; Gr1", "gene_names_refseq": "D8Ertd238e; Gr-1; Gr1; Gsr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P47791", "url": "https://www.uniprot.org/uniprotkb/P47791" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "YGKDNVKIYSTAFTPMYHAV", "down_seq": "TRKTKCVMKMVCANKEEKVV", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr433", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "297", "end_pos": "297" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P47791-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P47791-1", "length": 500, "uniprot_id": "GSHR_MOUSE", "protein_name": "Glutathione reductase, mitochondrial", "refseq_ac": "NP_034474", "refseq_name": "glutathione reductase, mitochondrial precursor", "gene_name": "Gsr", "gene_names_uniprotkb": "Gsr; Gr1", "gene_names_refseq": "D8Ertd238e; Gr-1; Gr1; Gsr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P47791", "url": "https://www.uniprot.org/uniprotkb/P47791" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P47791", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P47791" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P47791", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P47791" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "P47791", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P47791" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P47791", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P47791" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P47791", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P47791", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P47791", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P47791" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "297", "end_pos": "297" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P47791-1.297.297", "start_pos": 297, "end_pos": 297, "uniprot_canonical_ac": "P47791-1", "length": 500, "uniprot_id": "GSHR_MOUSE", "protein_name": "Glutathione reductase, mitochondrial", "refseq_ac": "NP_034474", "refseq_name": "glutathione reductase, mitochondrial precursor", "gene_name": "Gsr", "gene_names_uniprotkb": "Gsr; Gr1", "gene_names_refseq": "D8Ertd238e; Gr-1; Gr1; Gsr", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P47791", "url": "https://www.uniprot.org/uniprotkb/P47791" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3388979338", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388979338", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KKTSSGLELQVVTSVPGRKP", "down_seq": "TTMIPDVDCLLWAIGRDPNS", "snv": [ { "evidence": [ { "id": "rs3388979338", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3388979338" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "sequence_org": "T", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (TTT->NTT).", "chr_id": "8", "chr_pos": "34175645", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "T297", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "433", "end_pos": "433" } ] }, { "type": "snv", "site_list": [ { "start_pos": "255", "end_pos": "255" }, { "start_pos": "297", "end_pos": "297" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q61425-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q61425-1", "length": 314, "uniprot_id": "HCDH_MOUSE", "protein_name": "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial", "refseq_ac": "NP_032238", "refseq_name": "hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor", "gene_name": "Hadh", "gene_names_uniprotkb": "Hadh; Hadhsc; Mschad; Schad", "gene_names_refseq": "HCDH; Hadhsc; Hadh; Schad", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q61425", "url": "https://www.uniprot.org/uniprotkb/Q61425" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61425" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61425" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] }, { "title": "A reference dataset of O-GlcNAc proteins in quadriceps skeletal muscle from mice.", "journal": "Glycobiology", "date": "2025-02-10", "authors": "Jaiswal Ruchi, Liu Yimin, Petriello Michael, Zhang Xiangmin, Yi Zhengping, Fehl Charlie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61425" } ], "reference": [ { "type": "PubMed", "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985" } ] }, { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q61425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61425" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q61425", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61425", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343", "database": "PubMed", "categories": [ "Other" ] }, { "id": "39927985", "url": "https://glygen.org/publication/PubMed/39927985", "database": "PubMed", "categories": [ "Other" ] }, { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "Q61425", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q61425" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "39927985", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39927985" }, { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "all_sites": [], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8CJI4-1.38.38", "start_pos": 38, "end_pos": 38, "uniprot_canonical_ac": "Q8CJI4-1", "length": 398, "uniprot_id": "H1FNT_MOUSE", "protein_name": "Testis-specific H1 histone", "refseq_ac": "NP_081580", "refseq_name": "testis-specific H1 histone", "gene_name": "H1-7", "gene_names_uniprotkb": "H1-7; H1f7; H1fnt; Hanp1", "gene_names_refseq": "1700026P10Rik; H1-7; H1.7; H1f7; H1fnt; H1t2; Hanp1; mH1t2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8CJI4", "url": "https://www.uniprot.org/uniprotkb/Q8CJI4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8CJI4", "url": "https://www.uniprot.org/uniprotkb/Q8CJI4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IQIQQPAERALRTPAKRGTQ", "down_seq": "VLRVSQLLLRAIAGHQHLTL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8CJI4", "url": "https://www.uniprot.org/uniprotkb/Q8CJI4" } ], "site_lbl": "Ser38" } ], "all_sites": [ { "type": "phosphorylation", "site_list": [ { "start_pos": "38", "end_pos": "38" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08680-1.47.47", "start_pos": 47, "end_pos": 47, "uniprot_canonical_ac": "P08680-1", "length": 587, "uniprot_id": "HEM0_MOUSE", "protein_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "refseq_ac": "NP_001095916", "refseq_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform b", "gene_name": "Alas2", "gene_names_uniprotkb": "Alas2", "gene_names_refseq": "ALAS-E; ALASE; ALAS; Alas-2; Alas2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KTYQFLFSIGRCPILATQGP", "down_seq": "CSQIHLKATKAGGDSPSWAK", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "391", "end_pos": "391" } ] }, { "type": "snv", "site_list": [ { "start_pos": "523", "end_pos": "523" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P08680-1.391.391", "start_pos": 391, "end_pos": 391, "uniprot_canonical_ac": "P08680-1", "length": 587, "uniprot_id": "HEM0_MOUSE", "protein_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "refseq_ac": "NP_001095916", "refseq_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform b", "gene_name": "Alas2", "gene_names_uniprotkb": "Alas2", "gene_names_refseq": "ALAS-E; ALASE; ALAS; Alas-2; Alas2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Heme biosynthesis in mammalian systems: evidence of a Schiff base linkage between the pyridoxal 5'-phosphate cofactor and a lysine residue in 5-aminolevulinate synthase.", "journal": "Protein science : a publication of the Protein Society", "date": "1993", "authors": "Ferreira GC, Neame PJ, Dailey HA", "evidence": [ { "database": "UniProtKB", "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680" } ], "reference": [ { "type": "PubMed", "id": "8268805", "url": "https://glygen.org/publication/PubMed/8268805" } ] } ], "crossref": [ { "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "8268805", "url": "https://glygen.org/publication/PubMed/8268805", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "K", "start_aa": "K", "up_seq": "GIGERDGIMHKLDIISGTLG", "down_seq": "AFGCVGGYIASTRDLVDMVR", "mutagenesis": [ { "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680" }, { "database": "PubMed", "id": "8268805", "url": "https://glygen.org/publication/PubMed/8268805" } ] }, { "sequence_org": "K", "sequence_mut": "H", "comment": "Abolishes enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680" }, { "database": "PubMed", "id": "8268805", "url": "https://glygen.org/publication/PubMed/8268805" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "391", "end_pos": "391" } ] }, { "type": "snv", "site_list": [ { "start_pos": "523", "end_pos": "523" } ] } ], "categories": [ "mutagenesis_flag" ], "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": true, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P08680-1.523.523", "start_pos": 523, "end_pos": 523, "uniprot_canonical_ac": "P08680-1", "length": 587, "uniprot_id": "HEM0_MOUSE", "protein_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "refseq_ac": "NP_001095916", "refseq_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform b", "gene_name": "Alas2", "gene_names_uniprotkb": "Alas2", "gene_names_refseq": "ALAS-E; ALASE; ALAS; Alas-2; Alas2", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P08680", "url": "https://www.uniprot.org/uniprotkb/P08680" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "rs3508190732", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3508190732", "database": "dbSNP", "categories": [ "Other" ] } ], "site_seq": "H", "start_aa": "H", "up_seq": "AINYPTVPRGEELLRLAPSP", "down_seq": "HSPQMMENFVEKLLLAWTEV", "snv": [ { "evidence": [ { "id": "rs3508190732", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3508190732" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "sequence_org": "H", "sequence_mut": "N", "comment": "Germline mutation passed 1 filters: n-glyco-sequon-gain (HHS->NHS).", "chr_id": "X", "chr_pos": "149349626", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "H523", "keywords": [ "ebi", "germline" ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "47", "end_pos": "47" } ] }, { "type": "mutagenesis", "site_list": [ { "start_pos": "391", "end_pos": "391" } ] }, { "type": "snv", "site_list": [ { "start_pos": "523", "end_pos": "523" } ] } ], "categories": [ "snv_flag" ], "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": true, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09106-1.349.349", "start_pos": 349, "end_pos": 349, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "PYNDYFEYFGPDFKLHISPS", "down_seq": "MTNQNTNEYLEKIKQRLFEN", "glycosylation": [ { "glytoucan_ac": "G90659AW", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "LHISPSNMTNQNTNEYLEK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn349", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09106-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation is required for B cell homeostasis and antibody responses.", "journal": "Nature communications", "date": "2017", "authors": "Wu JL, Chiang MF, Hsu PH, Tsai DY, Hung KH, Wang YH, Angata T, Lin KI", "evidence": [ { "database": "O-GlcNAc Database", "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" } ], "reference": [ { "type": "PubMed", "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734" } ] }, { "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.", "journal": "Journal of the American Chemical Society", "date": "2014", "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" } ], "reference": [ { "type": "PubMed", "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642" } ] }, { "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.", "journal": "Journal of the American Chemical Society", "date": "2017", "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" } ], "reference": [ { "type": "PubMed", "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544" } ] }, { "title": "The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.", "journal": "ACS chemical biology", "date": "2017", "authors": "Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR", "evidence": [ { "database": "O-GlcNAc Database", "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" } ], "reference": [ { "type": "PubMed", "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057" } ] }, { "title": "Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy.", "journal": "American journal of physiology. Heart and circulatory physiology", "date": "2013", "authors": "Medford HM, Porter K, Marsh SA", "evidence": [ { "database": "O-GlcNAc Database", "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" } ], "reference": [ { "type": "PubMed", "id": "23624624", "url": "https://glygen.org/publication/PubMed/23624624" } ] }, { "title": "O-GlcNAc transferase inhibits LPS-mediated expression of inducible nitric oxide synthase through an increased interaction with mSin3A in RAW264.7 cells.", "journal": "American journal of physiology. Cell physiology", "date": "2013", "authors": "Hwang SY, Hwang JS, Kim SY, Han IO", "evidence": [ { "database": "O-GlcNAc Database", "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" } ], "reference": [ { "type": "PubMed", "id": "23824843", "url": "https://glygen.org/publication/PubMed/23824843" } ] } ], "crossref": [ { "id": "29187734", "url": "https://glygen.org/publication/PubMed/29187734", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O09106", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "25153642", "url": "https://glygen.org/publication/PubMed/25153642", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28528544", "url": "https://glygen.org/publication/PubMed/28528544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "28135057", "url": "https://glygen.org/publication/PubMed/28135057", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23624624", "url": "https://glygen.org/publication/PubMed/23624624", "database": "PubMed", "categories": [ "Other" ] }, { "id": "23824843", "url": "https://glygen.org/publication/PubMed/23824843", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29187734", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/29187734" }, { "id": "O09106", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O09106" }, { "id": "25153642", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/25153642" }, { "id": "28528544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28528544" }, { "id": "28135057", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28135057" }, { "id": "23624624", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23624624" }, { "id": "23824843", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23824843" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09106-1.393.393", "start_pos": 393, "end_pos": 393, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LPHAPGVQMQAIPEDAIPEE", "down_seq": "GDEDEEDPDKRISICSSDKR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "site_lbl": "Ser393" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "O09106-1.406.406", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "O09106-1.409.409", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09106-1.406.406", "start_pos": 406, "end_pos": 406, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EDAIPEESGDEDEEDPDKRI", "down_seq": "ICSSDKRIACEEEFSDSDEE", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "site_lbl": "Ser406" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "O09106-1.393.393", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "upstream", "id": "O09106-1.409.409", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "O09106-1.421.421", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "O09106-1.423.423", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09106-1.409.409", "start_pos": 409, "end_pos": 409, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "IPEESGDEDEEDPDKRISIC", "down_seq": "SDKRIACEEEFSDSDEEGEG", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "site_lbl": "Ser409" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 16, "direction": "downstream", "id": "O09106-1.393.393", "categories": [ "phosphorylation_flag" ] }, { "distance": 3, "direction": "downstream", "id": "O09106-1.406.406", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "upstream", "id": "O09106-1.421.421", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "upstream", "id": "O09106-1.423.423", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "O09106-1.421.421", "start_pos": 421, "end_pos": 421, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling.", "journal": "Molecular biology of the cell", "date": "2017", "authors": "Masoumi KC, Daams R, Sime W, Siino V, Ke H, Levander F, Massoumi R", "evidence": [ { "database": "iPTMnet", "id": "O09106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09106" } ], "reference": [ { "type": "PubMed", "id": "27903773", "url": "https://glygen.org/publication/PubMed/27903773" } ] } ], "crossref": [ { "id": "O09106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09106", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "27903773", "url": "https://glygen.org/publication/PubMed/27903773", "database": "PubMed", "categories": [ "Other" ] }, { "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PDKRISICSSDKRIACEEEF", "down_seq": "DSDEEGEGGRKNSSNFKKAK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "O54949-1", "kinase_gene_name": "Nlk", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O09106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09106" }, { "database": "PubMed", "id": "27903773", "url": "https://glygen.org/publication/PubMed/27903773" } ], "site_lbl": "Ser421" }, { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "site_lbl": "Ser421" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "O09106-1.406.406", "categories": [ "phosphorylation_flag" ] }, { "distance": 12, "direction": "downstream", "id": "O09106-1.409.409", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "O09106-1.423.423", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "O09106-1.423.423", "start_pos": 423, "end_pos": 423, "uniprot_canonical_ac": "O09106-1", "length": 482, "uniprot_id": "HDAC1_MOUSE", "protein_name": "Histone deacetylase 1", "refseq_ac": "NP_032254", "refseq_name": "histone deacetylase 1", "gene_name": "Hdac1", "gene_names_uniprotkb": "Hdac1", "gene_names_refseq": "HD1; Hdac1-ps; Hdac1; MommeD5; RPD3", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling.", "journal": "Molecular biology of the cell", "date": "2017", "authors": "Masoumi KC, Daams R, Sime W, Siino V, Ke H, Levander F, Massoumi R", "evidence": [ { "database": "iPTMnet", "id": "O09106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09106" } ], "reference": [ { "type": "PubMed", "id": "27903773", "url": "https://glygen.org/publication/PubMed/27903773" } ] } ], "crossref": [ { "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "O09106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09106", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "27903773", "url": "https://glygen.org/publication/PubMed/27903773", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KRISICSSDKRIACEEEFSD", "down_seq": "DEEGEGGRKNSSNFKKAKRV", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O09106", "url": "https://www.uniprot.org/uniprotkb/O09106" }, { "database": "iPTMnet", "id": "O09106", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O09106" }, { "database": "PubMed", "id": "27903773", "url": "https://glygen.org/publication/PubMed/27903773" } ], "site_lbl": "Ser423" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "349", "end_pos": "349" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "393", "end_pos": "393" }, { "start_pos": "406", "end_pos": "406" }, { "start_pos": "409", "end_pos": "409" }, { "start_pos": "421", "end_pos": "421" }, { "start_pos": "423", "end_pos": "423" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "O09106-1.406.406", "categories": [ "phosphorylation_flag" ] }, { "distance": 14, "direction": "downstream", "id": "O09106-1.409.409", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "O09106-1.421.421", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P10854-1.113.113", "start_pos": 113, "end_pos": 113, "uniprot_canonical_ac": "P10854-1", "length": 126, "uniprot_id": "H2B1M_MOUSE", "protein_name": "Histone H2B type 1-M", "refseq_ac": "NP_835507", "refseq_name": "histone H2B type 1-M", "gene_name": "H2bc14", "gene_names_uniprotkb": "H2bc14; Hist1h2bm", "gene_names_refseq": "H2b-291b; H2bc14; Hist1h2bm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "REIQTAVRLLLPGELAKHAV", "down_seq": "EGTKAVTKYTSSK", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "P10854", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10854#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "P10854-1.116.116", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P10854-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P10854-1", "length": 126, "uniprot_id": "H2B1M_MOUSE", "protein_name": "Histone H2B type 1-M", "refseq_ac": "NP_835507", "refseq_name": "histone H2B type 1-M", "gene_name": "H2bc14", "gene_names_uniprotkb": "H2bc14; Hist1h2bm", "gene_names_refseq": "H2b-291b; H2bc14; Hist1h2bm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Differential Detection of O-GlcNAcylated proteins in the heart using antibodies.", "journal": "Analytical biochemistry", "date": "2023-10-01", "authors": "Narayanan Bhargavi, Zahra Fiddia, Reeves Russell A, Aggarwal Akanksha, O'Meally Robert N, Henry Roger K, Craven Megan, Jacobson Avital, Cole Robert N, Kohr Mark J, Umapathi Priya, Zachara Natasha E", "evidence": [ { "database": "O-GlcNAc Database", "id": "P10854", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10854" } ], "reference": [ { "type": "PubMed", "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081" } ] } ], "crossref": [ { "id": "37507081", "url": "https://glygen.org/publication/PubMed/37507081", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P10854", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10854", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37507081", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37507081" }, { "id": "P10854", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P10854" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "P10854-1.15.15", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P10854-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "P10854-1", "length": 126, "uniprot_id": "H2B1M_MOUSE", "protein_name": "Histone H2B type 1-M", "refseq_ac": "NP_835507", "refseq_name": "histone H2B type 1-M", "gene_name": "H2bc14", "gene_names_uniprotkb": "H2bc14; Hist1h2bm", "gene_names_refseq": "H2b-291b; H2bc14; Hist1h2bm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QTAVRLLLPGELAKHAVSEG", "down_seq": "KAVTKYTSSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" } ], "site_lbl": "Thr116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "P10854-1.113.113", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P10854-1.15.15", "start_pos": 15, "end_pos": 15, "uniprot_canonical_ac": "P10854-1", "length": 126, "uniprot_id": "H2B1M_MOUSE", "protein_name": "Histone H2B type 1-M", "refseq_ac": "NP_835507", "refseq_name": "histone H2B type 1-M", "gene_name": "H2bc14", "gene_names_uniprotkb": "H2bc14; Hist1h2bm", "gene_names_refseq": "H2b-291b; H2bc14; Hist1h2bm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation of histone H2B at DNA double-strand breaks.", "journal": "The Journal of experimental medicine", "date": "2004", "authors": "Fernandez-Capetillo O, Allis CD, Nussenzweig A", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" }, { "database": "iPTMnet", "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854" } ], "reference": [ { "type": "PubMed", "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225" } ] }, { "title": "Histone modifications associated with somatic hypermutation.", "journal": "Immunity", "date": "2005", "authors": "Odegard VH, Kim ST, Anderson SM, Shlomchik MJ, Schatz DG", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" }, { "database": "iPTMnet", "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854" } ], "reference": [ { "type": "PubMed", "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583" } ] } ], "crossref": [ { "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPEPTKSAPAPKKG", "down_seq": "KKAVTKAQKKDGKKRKRSRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by STK4/MST1", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" }, { "database": "iPTMnet", "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854" }, { "database": "PubMed", "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225" }, { "database": "PubMed", "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583" } ], "site_lbl": "Ser15" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P10854-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P10854-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "P10854-1", "length": 126, "uniprot_id": "H2B1M_MOUSE", "protein_name": "Histone H2B type 1-M", "refseq_ac": "NP_835507", "refseq_name": "histone H2B type 1-M", "gene_name": "H2bc14", "gene_names_uniprotkb": "H2bc14; Hist1h2bm", "gene_names_refseq": "H2b-291b; H2bc14; Hist1h2bm", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis.", "journal": "Molecular cell", "date": "2020", "authors": "Huang D, Camacho CV, Setlem R, Ryu KW, Parameswaran B, Gupta RK, Kraus WL", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" }, { "database": "iPTMnet", "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854" } ], "reference": [ { "type": "PubMed", "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587" } ] }, { "title": "Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation.", "journal": "Science (New York, N.Y.)", "date": "2010", "authors": "Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" }, { "database": "iPTMnet", "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854" } ], "reference": [ { "type": "PubMed", "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423" } ] } ], "crossref": [ { "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KAVTKAQKKDGKKRKRSRKE", "down_seq": "YSVYVYKVLKQVHPDTGISS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by AMPK", "evidence": [ { "database": "UniProtKB", "id": "P10854", "url": "https://www.uniprot.org/uniprotkb/P10854" }, { "database": "iPTMnet", "id": "P10854", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P10854" }, { "database": "PubMed", "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587" }, { "database": "PubMed", "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423" } ], "site_lbl": "Ser37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P34914-1.50.50", "start_pos": 50, "end_pos": 50, "uniprot_canonical_ac": "P34914-1", "length": 554, "uniprot_id": "HYES_MOUSE", "protein_name": "Bifunctional epoxide hydrolase 2", "refseq_ac": "NP_001258332", "refseq_name": "bifunctional epoxide hydrolase 2 isoform c", "gene_name": "Ephx2", "gene_names_uniprotkb": "Ephx2; Eph2", "gene_names_refseq": "CEH; Eph2; Ephx2; SEH; sEP", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "GLY_001153", "url": "https://data.glygen.org/GLY_001153", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "LALPRDFLLGAYQTEFPEGP", "down_seq": "EQLMKGKITFSQWVPLMDES", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Thr", "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001153", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001153" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "50", "end_pos": "50" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "368", "end_pos": "368" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P34914-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P34914-1", "length": 554, "uniprot_id": "HYES_MOUSE", "protein_name": "Bifunctional epoxide hydrolase 2", "refseq_ac": "NP_001258332", "refseq_name": "bifunctional epoxide hydrolase 2 isoform c", "gene_name": "Ephx2", "gene_names_uniprotkb": "Ephx2; Eph2", "gene_names_refseq": "CEH; Eph2; Ephx2; SEH; sEP", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function.", "journal": "Molecular metabolism", "date": "2023-09", "authors": "Gonzalez-Rellan Maria J, Parracho Tamara, Heras Violeta, Rodriguez Amaia, Fondevila Marcos F, Novoa Eva, Lima Natalia, Varela-Rey Marta, Senra Ana, Chantada-Vazquez Maria D P, Ameneiro Cristina, Bernardo Ganeko, Fernandez-Ramos David, Lopitz-Otsoa Fernando, Bilbao Jon, Guallar Diana, Fidalgo Miguel, Bravo Susana, Dieguez Carlos, Martinez-Chantar Maria L, Millet Oscar, Mato Jose M, Schwaninger Markus, Prevot Vincent, Crespo Javier, Fr\u00fchbeck Gema, Iruzubieta Paula, Nogueiras Ruben", "evidence": [ { "database": "O-GlcNAc Database", "id": "P34914", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P34914" } ], "reference": [ { "type": "PubMed", "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P34914", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P34914" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "37453647", "url": "https://glygen.org/publication/PubMed/37453647", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P34914", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P34914", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "37453647", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37453647" }, { "id": "P34914", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P34914" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "50", "end_pos": "50" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "368", "end_pos": "368" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P34914-1.368.368", "start_pos": 368, "end_pos": 368, "uniprot_canonical_ac": "P34914-1", "length": 554, "uniprot_id": "HYES_MOUSE", "protein_name": "Bifunctional epoxide hydrolase 2", "refseq_ac": "NP_001258332", "refseq_name": "bifunctional epoxide hydrolase 2 isoform c", "gene_name": "Ephx2", "gene_names_uniprotkb": "Ephx2; Eph2", "gene_names_refseq": "CEH; Eph2; Ephx2; SEH; sEP", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914" }, { "database": "iPTMnet", "id": "P34914", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34914" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914" }, { "database": "iPTMnet", "id": "P34914", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34914" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P34914", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34914", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ERVRAVASLNTPFMPPDPDV", "down_seq": "PMKVIRSIPVFNYQLYFQEP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P34914", "url": "https://www.uniprot.org/uniprotkb/P34914" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "P34914", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34914" } ], "site_lbl": "Ser368" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "50", "end_pos": "50" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "368", "end_pos": "368" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q64478-1.113.113", "start_pos": 113, "end_pos": 113, "uniprot_canonical_ac": "Q64478-1", "length": 126, "uniprot_id": "H2B1H_MOUSE", "protein_name": "Histone H2B type 1-H", "refseq_ac": "NP_835504", "refseq_name": "histone H2B type 1-H", "gene_name": "H2bc9", "gene_names_uniprotkb": "H2bc9; Hist1h2bh", "gene_names_refseq": "H2b-221; H2bc9; Hist1h2bh", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "REIQTAVRLLLPGELAKHAV", "down_seq": "EGTKAVTKYTSSK", "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GlcNAc) serine;O-GlcNAcylation", "icn3d_view": {}, "start_aa": "Ser", "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser113", "evidence": [ { "id": "Q64478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q64478#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "upstream", "id": "Q64478-1.116.116", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q64478-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q64478-1", "length": 126, "uniprot_id": "H2B1H_MOUSE", "protein_name": "Histone H2B type 1-H", "refseq_ac": "NP_835504", "refseq_name": "histone H2B type 1-H", "gene_name": "H2bc9", "gene_names_uniprotkb": "H2bc9; Hist1h2bh", "gene_names_refseq": "H2b-221; H2bc9; Hist1h2bh", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q64478", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q64478" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q64478", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q64478", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" }, { "id": "Q64478", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q64478" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "upstream", "id": "Q64478-1.15.15", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q64478-1.116.116", "start_pos": 116, "end_pos": 116, "uniprot_canonical_ac": "Q64478-1", "length": 126, "uniprot_id": "H2B1H_MOUSE", "protein_name": "Histone H2B type 1-H", "refseq_ac": "NP_835504", "refseq_name": "histone H2B type 1-H", "gene_name": "H2bc9", "gene_names_uniprotkb": "H2bc9; Hist1h2bh", "gene_names_refseq": "H2b-221; H2bc9; Hist1h2bh", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "QTAVRLLLPGELAKHAVSEG", "down_seq": "KAVTKYTSSK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" } ], "site_lbl": "Thr116" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 3, "direction": "downstream", "id": "Q64478-1.113.113", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q64478-1.15.15", "start_pos": 15, "end_pos": 15, "uniprot_canonical_ac": "Q64478-1", "length": 126, "uniprot_id": "H2B1H_MOUSE", "protein_name": "Histone H2B type 1-H", "refseq_ac": "NP_835504", "refseq_name": "histone H2B type 1-H", "gene_name": "H2bc9", "gene_names_uniprotkb": "H2bc9; Hist1h2bh", "gene_names_refseq": "H2b-221; H2bc9; Hist1h2bh", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Phosphorylation of histone H2B at DNA double-strand breaks.", "journal": "The Journal of experimental medicine", "date": "2004", "authors": "Fernandez-Capetillo O, Allis CD, Nussenzweig A", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" }, { "database": "iPTMnet", "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478" } ], "reference": [ { "type": "PubMed", "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225" } ] }, { "title": "Histone modifications associated with somatic hypermutation.", "journal": "Immunity", "date": "2005", "authors": "Odegard VH, Kim ST, Anderson SM, Shlomchik MJ, Schatz DG", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" }, { "database": "iPTMnet", "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478" } ], "reference": [ { "type": "PubMed", "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583" } ] } ], "crossref": [ { "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225", "database": "PubMed", "categories": [ "Other" ] }, { "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "MPEPAKSAPAPKKG", "down_seq": "KKALTKAQKKDGKKRKRSRK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by STK4/MST1", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" }, { "database": "iPTMnet", "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478" }, { "database": "PubMed", "id": "15197225", "url": "https://glygen.org/publication/PubMed/15197225" }, { "database": "PubMed", "id": "16039583", "url": "https://glygen.org/publication/PubMed/16039583" } ], "site_lbl": "Ser15" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q64478-1.0.0", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q64478-1.37.37", "start_pos": 37, "end_pos": 37, "uniprot_canonical_ac": "Q64478-1", "length": 126, "uniprot_id": "H2B1H_MOUSE", "protein_name": "Histone H2B type 1-H", "refseq_ac": "NP_835504", "refseq_name": "histone H2B type 1-H", "gene_name": "H2bc9", "gene_names_uniprotkb": "H2bc9; Hist1h2bh", "gene_names_refseq": "H2b-221; H2bc9; Hist1h2bh", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis.", "journal": "Molecular cell", "date": "2020", "authors": "Huang D, Camacho CV, Setlem R, Ryu KW, Parameswaran B, Gupta RK, Kraus WL", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" }, { "database": "iPTMnet", "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478" } ], "reference": [ { "type": "PubMed", "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587" } ] }, { "title": "Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation.", "journal": "Science (New York, N.Y.)", "date": "2010", "authors": "Bungard D, Fuerth BJ, Zeng PY, Faubert B, Maas NL, Viollet B, Carling D, Thompson CB, Jones RG, Berger SL", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" }, { "database": "iPTMnet", "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478" } ], "reference": [ { "type": "PubMed", "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423" } ] } ], "crossref": [ { "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478", "database": "iPTMnet", "categories": [ "Other" ] }, { "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587", "database": "PubMed", "categories": [ "Other" ] }, { "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423", "database": "PubMed", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "KALTKAQKKDGKKRKRSRKE", "down_seq": "YSVYVYKVLKQVHPDTGISS", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by AMPK", "evidence": [ { "database": "UniProtKB", "id": "Q64478", "url": "https://www.uniprot.org/uniprotkb/Q64478" }, { "database": "iPTMnet", "id": "Q64478", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q64478" }, { "database": "PubMed", "id": "32822587", "url": "https://glygen.org/publication/PubMed/32822587" }, { "database": "PubMed", "id": "20647423", "url": "https://glygen.org/publication/PubMed/20647423" } ], "site_lbl": "Ser37" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "113", "end_pos": "113" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "116", "end_pos": "116" }, { "start_pos": "15", "end_pos": "15" }, { "start_pos": "37", "end_pos": "37" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11835-1.117.117", "start_pos": 117, "end_pos": 117, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "KQLSPQKVTLYLRPGQAAAF", "down_seq": "VTFRRAKGYPIDLYYLMDLS", "glycosylation": [ { "glytoucan_ac": "G28541PG", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "PGQAAAFNVTFR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn117", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn117", "evidence": [ { "id": "P11835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11835#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11835-1.255.255", "start_pos": 255, "end_pos": 255, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EGGLDAIMQVAACPEEIGWR", "down_seq": "VTRLLVFATDDGFHFAGDGK", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn255", "evidence": [ { "id": "P11835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11835#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11835-1.502.502", "start_pos": 502, "end_pos": 502, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "CECQTQGRSSQELERNCRKD", "down_seq": "SSIVCSGLGDCICGQCVCHT", "glycosylation": [ { "glytoucan_ac": "G60033FS", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DNSSIVCSGLGDCICGQCVCHTSDVPNK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn502", "evidence": [ { "id": "P11835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11835#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11835-1.51.51", "start_pos": 51, "end_pos": 51, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "VSSCRDCIQSGPGCSWCQKL", "down_seq": "FTGPGEPDSLRCDTRAQLLL", "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn51", "evidence": [ { "id": "P11835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11835#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11835-1.626.626", "start_pos": 626, "end_pos": 626, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2404", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2404", "url": "https://glyconnect.expasy.org/browser/proteins/2404", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EGYQPPMCEDCPSCGSHCRD", "down_seq": "HTSCAECLKFDKGPFEKNCS", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn626", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2404", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ] }, { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "DNHTSCAECLK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn626", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "G64527OM", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn626", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2404", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ] }, { "glytoucan_ac": "G70101JE", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn626", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2404", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn626", "evidence": [ { "id": "P11835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11835#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "upstream", "id": "P11835-1.644.644", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11835-1.644.644", "start_pos": 644, "end_pos": 644, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis.", "journal": "Nature communications", "date": "2019", "authors": "Riley NM, Hebert AS, Westphall MS, Coon JJ", "evidence": [ { "database": "GlyConnect", "id": "2404", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ], "reference": [ { "type": "PubMed", "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004" } ] }, { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "30899004", "url": "https://glygen.org/publication/PubMed/30899004", "database": "PubMed", "categories": [ "Other" ] }, { "id": "2404", "url": "https://glyconnect.expasy.org/browser/proteins/2404", "database": "GlyConnect", "categories": [ "Glycomics", "Glycoproteomics" ] }, { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] }, { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "RDNHTSCAECLKFDKGPFEK", "down_seq": "CSVQCAGMTLQTIPLKKKPC", "glycosylation": [ { "glytoucan_ac": "G05724UK", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn644", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2404", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ] }, { "glytoucan_ac": "G39188ZX", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn644", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2404", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ] }, { "glytoucan_ac": "G46902YN", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn644", "evidence": [ { "id": "30899004", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30899004" }, { "id": "2404", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/2404" } ] }, { "glytoucan_ac": "G62765YT", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NCSVQCAGMTLQTIPLKK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn644", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn644", "evidence": [ { "id": "P11835", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11835#ptm_processing" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 18, "direction": "downstream", "id": "P11835-1.626.626", "categories": [ "glycosylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 4 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 4 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11835-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11835", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11835" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "P11835", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11835" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "P11835", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11835", "database": "O-GlcNAc Database", "categories": [ "Other" ] }, { "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544", "database": "PubMed", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "P11835", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=P11835" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "P11835-1.747.747", "start_pos": 747, "end_pos": 747, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ALTHLTDLREYRRFEKEKLK", "down_seq": "QWNNDNPLFKSATTTVMNPK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "site_lbl": "Ser747" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "upstream", "id": "P11835-1.758.758", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "P11835-1.760.760", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "P11835-1.762.762", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11835-1.758.758", "start_pos": 758, "end_pos": 758, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "RRFEKEKLKSQWNNDNPLFK", "down_seq": "ATTTVMNPKFAES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "site_lbl": "Ser758" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 11, "direction": "downstream", "id": "P11835-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P11835-1.760.760", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "P11835-1.762.762", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11835-1.760.760", "start_pos": 760, "end_pos": 760, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "FEKEKLKSQWNNDNPLFKSA", "down_seq": "TTVMNPKFAES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "site_lbl": "Thr760" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "P11835-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P11835-1.758.758", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "P11835-1.762.762", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "P11835-1.762.762", "start_pos": 762, "end_pos": 762, "uniprot_canonical_ac": "P11835-1", "length": 771, "uniprot_id": "ITB2_MOUSE", "protein_name": "Integrin beta-2", "refseq_ac": "NP_032430", "refseq_name": "integrin beta-2 isoform 1 precursor", "gene_name": "Itgb2", "gene_names_uniprotkb": "Itgb2", "gene_names_refseq": "2E6; Cd18; Itgb2; LAD; LCAMB; Lfa1; MF17", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "T", "start_aa": "T", "up_seq": "KEKLKSQWNNDNPLFKSATT", "down_seq": "VMNPKFAES", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "P11835", "url": "https://www.uniprot.org/uniprotkb/P11835" } ], "site_lbl": "Thr762" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "117", "end_pos": "117" }, { "start_pos": "255", "end_pos": "255" }, { "start_pos": "502", "end_pos": "502" }, { "start_pos": "51", "end_pos": "51" }, { "start_pos": "626", "end_pos": "626" }, { "start_pos": "644", "end_pos": "644" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "747", "end_pos": "747" }, { "start_pos": "758", "end_pos": "758" }, { "start_pos": "760", "end_pos": "760" }, { "start_pos": "762", "end_pos": "762" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "P11835-1.747.747", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "P11835-1.758.758", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "P11835-1.760.760", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.351.351", "start_pos": 351, "end_pos": 351, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Deep quantitative glycoproteomics reveals gut microbiome induced remodeling of the brain glycoproteome", "journal": "bioRxiv", "date": "2023", "authors": "Potel C.M., Burtscher M.L., Garrido-Rodriguez M., Brauer-Nikonow A., Becher I., Typas A., Zimmermann M., Savitski M.", "evidence": [ { "database": "GlyGen", "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889" } ], "reference": [ { "type": "DOI", "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" } ] } ], "crossref": [ { "id": "10.1101/2023.09.13.557529", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529", "database": "DOI", "categories": [ "Other" ] }, { "id": "GLY_000889", "url": "https://data.glygen.org/GLY_000889", "database": "GlyGen", "categories": [ "Other" ] } ], "site_seq": "N", "start_aa": "N", "up_seq": "EEKVAKRKAAVLSDSEDDAG", "down_seq": "ASAKKSRVVCDADDSDSDVV", "glycosylation": [ { "glytoucan_ac": "G95843QZ", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "KAAVLSDSEDDAGNASAKK", "relation": "attached", "comment": "", "icn3d_view": {}, "start_aa": "Asn", "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn351", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000889", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000889" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 8, "direction": "downstream", "id": "Q8C1D8-1.343.343", "categories": [ "phosphorylation_flag" ] }, { "distance": 6, "direction": "downstream", "id": "Q8C1D8-1.345.345", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.366.366", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8C1D8-1.368.368", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 1 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_aa", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.0.0", "start_pos": 0, "end_pos": 0, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development.", "journal": "Cellular & molecular immunology", "date": "2025-01", "authors": "Jeon Bong Chan, Kim Yu-Ji, Park Ae Kyung, Song Mi-Ran, Na Ki Myeong, Lee Juwon, An Dasom, Park Yeseul, Hwang Heeyoun, Kim Tae-Don, Lim Junghyun, Park Sung-Kyun", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8C1D8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609" } ] } ], "crossref": [ { "id": "39627609", "url": "https://glygen.org/publication/PubMed/39627609", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8C1D8", "database": "O-GlcNAc Database", "categories": [ "Other" ] } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "39627609", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/39627609" }, { "id": "Q8C1D8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8C1D8" } ] } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "glycosylation_flag" ], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "biomarkers": [], "glycosylation_flag": true, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": false, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.157.157", "start_pos": 157, "end_pos": 157, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EVSKHAASDSEAEDTLQPQV", "down_seq": "ESDSEDPPRPQASDSENEEP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser157" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.170.170", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.172.172", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.170.170", "start_pos": 170, "end_pos": 170, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DTLQPQVSESDSEDPPRPQA", "down_seq": "DSENEEPPKPRISDSESEEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser170" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.157.157", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.183.183", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.172.172", "start_pos": 172, "end_pos": 172, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "LQPQVSESDSEDPPRPQASD", "down_seq": "ENEEPPKPRISDSESEELPK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser172" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.157.157", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.170.170", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.183.183", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.183.183", "start_pos": 183, "end_pos": 183, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPPRPQASDSENEEPPKPRI", "down_seq": "DSESEELPKPRVSDSESEDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser183" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.170.170", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8C1D8-1.172.172", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.196.196", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.198.198", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.196.196", "start_pos": 196, "end_pos": 196, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "EPPKPRISDSESEELPKPRV", "down_seq": "DSESEDPPRPQASDSESEEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser196" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.198.198", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.209.209", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.211.211", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.198.198", "start_pos": 198, "end_pos": 198, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKPRISDSESEELPKPRVSD", "down_seq": "ESEDPPRPQASDSESEELPK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser198" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.183.183", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.196.196", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.209.209", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.211.211", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.209.209", "start_pos": 209, "end_pos": 209, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELPKPRVSDSESEDPPRPQA", "down_seq": "DSESEELPKPRVSDSESEDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser209" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.196.196", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8C1D8-1.198.198", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.211.211", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.224.224", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.211.211", "start_pos": 211, "end_pos": 211, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKPRVSDSESEDPPRPQASD", "down_seq": "ESEELPKPRVSDSESEDPPR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser211" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.196.196", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.198.198", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.209.209", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.224.224", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.222.222", "start_pos": 222, "end_pos": 222, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPPRPQASDSESEELPKPRV", "down_seq": "DSESEDPPRPQASDSESEEL", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser222" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.209.209", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8C1D8-1.211.211", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.224.224", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.237.237", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.224.224", "start_pos": 224, "end_pos": 224, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRPQASDSESEELPKPRVSD", "down_seq": "ESEDPPRPQASDSESEELPK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser224" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.209.209", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.211.211", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.237.237", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.235.235", "start_pos": 235, "end_pos": 235, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355", "database": "PubMed", "categories": [ "Other" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELPKPRVSDSESEDPPRPQA", "down_seq": "DSESEELPKPRVSDSESEDP", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser235" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8C1D8-1.224.224", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.237.237", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.250.250", "categories": [ "phosphorylation_flag" ] }, { "distance": 17, "direction": "upstream", "id": "Q8C1D8-1.252.252", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.237.237", "start_pos": 237, "end_pos": 237, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PKPRVSDSESEDPPRPQASD", "down_seq": "ESEELPKPRVSDSESEDPQK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser237" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.222.222", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.224.224", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.250.250", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.252.252", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "id": "Q8C1D8-1.248.248", "start_pos": 248, "end_pos": 248, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "DPPRPQASDSESEELPKPRV", "down_seq": "DSESEDPQKGPASDSEAEDA", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser248" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8C1D8-1.237.237", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.250.250", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "upstream", "id": "Q8C1D8-1.252.252", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.261.261", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "upstream", "id": "Q8C1D8-1.263.263", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.250.250", "start_pos": 250, "end_pos": 250, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PRPQASDSESEELPKPRVSD", "down_seq": "ESEDPQKGPASDSEAEDASR", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser250" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.237.237", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.252.252", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.261.261", "categories": [ "phosphorylation_flag" ] }, { "distance": 13, "direction": "upstream", "id": "Q8C1D8-1.263.263", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.252.252", "start_pos": 252, "end_pos": 252, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "PQASDSESEELPKPRVSDSE", "down_seq": "EDPQKGPASDSEAEDASRHK", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "site_lbl": "Ser252" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 17, "direction": "downstream", "id": "Q8C1D8-1.235.235", "categories": [ "phosphorylation_flag" ] }, { "distance": 15, "direction": "downstream", "id": "Q8C1D8-1.237.237", "categories": [ "phosphorylation_flag" ] }, { "distance": 4, "direction": "downstream", "id": "Q8C1D8-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "downstream", "id": "Q8C1D8-1.250.250", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "upstream", "id": "Q8C1D8-1.261.261", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "upstream", "id": "Q8C1D8-1.263.263", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "id": "Q8C1D8-1.261.261", "start_pos": 261, "end_pos": 261, "uniprot_canonical_ac": "Q8C1D8-1", "length": 766, "uniprot_id": "IWS1_MOUSE", "protein_name": "Protein IWS1 homolog", "refseq_ac": "NP_775617", "refseq_name": "protein IWS1 homolog", "gene_name": "Iws1", "gene_names_uniprotkb": "Iws1; Iws1l", "gene_names_refseq": "1700069O15Rik; 3000008H23; Iws1", "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "publication": [ { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] } ], "crossref": [ { "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079", "database": "PubMed", "categories": [ "Other" ] }, { "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8", "database": "iPTMnet", "categories": [ "Other" ] } ], "site_seq": "S", "start_aa": "S", "up_seq": "ELPKPRVSDSESEDPQKGPA", "down_seq": "DSEAEDASRHKEKPDSDDSD", "phosphorylation": [ { "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8C1D8", "url": "https://www.uniprot.org/uniprotkb/Q8C1D8" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8C1D8", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8C1D8" } ], "site_lbl": "Ser261" } ], "all_sites": [ { "type": "glycosylation", "site_list": [ { "start_pos": "351", "end_pos": "351" } ] }, { "type": "phosphorylation", "site_list": [ { "start_pos": "157", "end_pos": "157" }, { "start_pos": "170", "end_pos": "170" }, { "start_pos": "172", "end_pos": "172" }, { "start_pos": "183", "end_pos": "183" }, { "start_pos": "196", "end_pos": "196" }, { "start_pos": "198", "end_pos": "198" }, { "start_pos": "209", "end_pos": "209" }, { "start_pos": "211", "end_pos": "211" }, { "start_pos": "222", "end_pos": "222" }, { "start_pos": "224", "end_pos": "224" }, { "start_pos": "235", "end_pos": "235" }, { "start_pos": "237", "end_pos": "237" }, { "start_pos": "248", "end_pos": "248" }, { "start_pos": "250", "end_pos": "250" }, { "start_pos": "252", "end_pos": "252" }, { "start_pos": "261", "end_pos": "261" }, { "start_pos": "263", "end_pos": "263" }, { "start_pos": "277", "end_pos": "277" }, { "start_pos": "27", "end_pos": "27" }, { "start_pos": "280", "end_pos": "280" }, { "start_pos": "295", "end_pos": "295" }, { "start_pos": "306", "end_pos": "306" }, { "start_pos": "307", "end_pos": "307" }, { "start_pos": "309", "end_pos": "309" }, { "start_pos": "321", "end_pos": "321" }, { "start_pos": "343", "end_pos": "343" }, { "start_pos": "345", "end_pos": "345" }, { "start_pos": "366", "end_pos": "366" }, { "start_pos": "368", "end_pos": "368" }, { "start_pos": "372", "end_pos": "372" }, { "start_pos": "381", "end_pos": "381" }, { "start_pos": "384", "end_pos": "384" }, { "start_pos": "386", "end_pos": "386" }, { "start_pos": "408", "end_pos": "408" }, { "start_pos": "410", "end_pos": "410" }, { "start_pos": "412", "end_pos": "412" }, { "start_pos": "427", "end_pos": "427" }, { "start_pos": "436", "end_pos": "436" }, { "start_pos": "458", "end_pos": "458" }, { "start_pos": "460", "end_pos": "460" }, { "start_pos": "54", "end_pos": "54" }, { "start_pos": "672", "end_pos": "672" }, { "start_pos": "69", "end_pos": "69" } ] } ], "categories": [ "phosphorylation_flag" ], "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "biomarkers": [], "neighbors": [ { "distance": 13, "direction": "downstream", "id": "Q8C1D8-1.248.248", "categories": [ "phosphorylation_flag" ] }, { "distance": 11, "direction": "downstream", "id": "Q8C1D8-1.250.250", "categories": [ "phosphorylation_flag" ] }, { "distance": 9, "direction": "downstream", "id": "Q8C1D8-1.252.252", "categories": [ "phosphorylation_flag" ] }, { "distance": 2, "direction": "upstream", "id": "Q8C1D8-1.263.263", "categories": [ "phosphorylation_flag" ] }, { "distance": 16, "direction": "upstream", "id": "Q8C1D8-1.277.277", "categories": [ "phosphorylation_flag" ] }, { "distance": 19, "direction": "upstream", "id": "Q8C1D8-1.280.280", "categories": [ "phosphorylation_flag" ] } ], "glycosylation_flag": false, "snv_flag": false, "mutagenesis_flag": false, "phosphorylation_flag": true, "glycation_flag": false, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] } ]