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hyperosmotic stress.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Lunn JA, Jacamo R, Rozengurt E", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "17289681", "url": "https://glygen.org/publication/PubMed/17289681" } ] }, { "title": "Focal adhesion kinase is negatively regulated by phosphorylation at tyrosine 407.", "journal": "The Journal of biological chemistry", "date": "2007-04-06", "authors": "Lim Yangmi, Park Haein, Jeon Jihyun, Han Innoc, Kim Jinsook, Jho Eek-Hoon, Oh Eok-Soo", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "17303567", "url": "https://glygen.org/publication/PubMed/17303567" } ] }, { "title": "Focal adhesion kinase (FAK) expression and activation during lens development.", "journal": 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Endocrinology and metabolism", "date": "2013-07-15", "authors": "Crossland Hannah, Kazi Abid A, Lang Charles H, Timmons James A, Pierre Philippe, Wilkinson Daniel J, Smith Kenneth, Szewczyk Nathaniel J, Atherton Philip J", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "23695213", "url": "https://glygen.org/publication/PubMed/23695213" } ] }, { "title": "p600 Plays Essential Roles in Fetal Development.", "journal": "PloS one", "date": "2013", "authors": "Nakaya Takeo, Ishiguro Kei-Ichiro, Belzil Camille, Rietsch Anna M, Yu Qunyan, Mizuno Shin-Ichi, Bronson Roderick T, Geng Yan, Nguyen Minh Dang, Akashi Koichi, Sicinski Piotr, Nakatani Yoshihiro", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "23824717", "url": 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"date": "2014-08-14", "authors": "Kolli-Bouhafs K, Sick E, Noulet F, Gies J-P, De Mey J, Rond\u00e9 P", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25118939", "url": "https://glygen.org/publication/PubMed/25118939" } ] }, { "title": "Generation of point-mutant FAK knockin mice.", "journal": "Genesis (New York, N.Y. : 2000)", "date": "2014-11", "authors": "Tavora B, Batista S, Alexopoulou A N, Kostourou V, Fernandez I, Robinson S D, Lees D M, Serrels B, Hodivala-Dilke K", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25242698", "url": "https://glygen.org/publication/PubMed/25242698" } ] }, { "title": "Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis.", "journal": "Arthritis research & therapy", "date": "2014-10-04", "authors": "Shelef Miriam A, Bennin David A, Yasmin Nihad, Warner Thomas F, Ludwig Thomas, Beggs Hilary E, Huttenlocher Anna", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25280866", "url": "https://glygen.org/publication/PubMed/25280866" } ] }, { "title": "Osmotic shrinkage elicits FAK- and Src phosphorylation and Src-dependent NKCC1 activation in NIH3T3 cells.", "journal": "American journal of physiology. Cell physiology", "date": "2015-01-15", "authors": "Rasmussen Line Jee Hartmann, M\u00fcller Helene Steenk\u00e6r Holm, J\u00f8rgensen Bente, Pedersen Stine Falsig, Hoffmann Else Kay", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25377086", "url": "https://glygen.org/publication/PubMed/25377086" } ] }, { "title": "Peripheral inflammation activated focal adhesion kinase signaling in spinal dorsal horn of mice.", "journal": "Journal of neuroscience research", "date": "2015-06", "authors": "Lian Xia, Wang Xin-Tai, Wang Wen-Tao, Yang Xian, Suo Zhan-Wei, Hu Xiao-Dong", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25612833", "url": "https://glygen.org/publication/PubMed/25612833" } ] }, { "title": "Expression of focal adhesion kinase in mouse cumulus-oocyte complexes, and effect of phosphorylation at Tyr397 on cumulus expansion.", "journal": "Molecular reproduction and development", "date": "2015-03", "authors": "Ohtake Jun, Sakurai Masahiro, Hoshino Yumi, Tanemura Kentaro, Sato Eimei", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25692763", "url": "https://glygen.org/publication/PubMed/25692763" } ] }, { "title": "3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling.", "journal": "Oncotarget", "date": "2015-09-15", "authors": "Li Wen-Xue, Chen Li-Ping, Sun Min-Ying, Li Jun-Tao, Liu Hua-Zhang, Zhu Wei", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "26068982", "url": 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fragment of Syndecan-1 is generated by sequential proteolysis and antagonizes Syndecan-1 dependent lung tumor cell migration.", "journal": "Oncotarget", "date": "2015", "authors": "Pasqualon T, Pruessmeyer J, Jankowski V, Babendreyer A, Groth E, Schumacher J, Koenen A, Weidenfeld S, Schwarz N, Denecke B, Jahr H, Dreymueller D, Jankowski J, Ludwig A", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "26378057", "url": "https://glygen.org/publication/PubMed/26378057" } ] }, { "title": "RNase L is a negative regulator of cell migration.", "journal": "Oncotarget", "date": "2015", "authors": "Banerjee S, Li G, Li Y, Gaughan C, Baskar D, Parker Y, Lindner DJ, Weiss SR, Silverman RH", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "26517238", "url": 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pathway induced by dexmedetomidine attenuates pulmonary microvascular hyper-permeability following kidney injury.", "journal": "Oncotarget", "date": "2016-08-30", "authors": "Chen Qian, Yi Bin, Ma Jianbo, Ning Jiaoling, Wu Lingzhi, Ma Daqing, Lu Kaizhi, Gu Jianteng", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "27463003", "url": "https://glygen.org/publication/PubMed/27463003" } ] }, { "title": "FAK deletion accelerates liver regeneration after two-thirds partial hepatectomy.", "journal": "Scientific reports", "date": "2016-09-28", "authors": "Shang Na, Arteaga Maribel, Chitsike Lennox, Wang Fang, Viswakarma Navin, Breslin Peter, Qiu Wei", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "27677358", "url": 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"journal": "Scientific reports", "date": "2017-06-09", "authors": "Lee Hui-Ju, Kao Chung-Yang, Lin Shih-Chieh, Xu Mafei, Xie Xin, Tsai Sophia Y, Tsai Ming-Jer", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "28600496", "url": "https://glygen.org/publication/PubMed/28600496" } ] }, { "title": "Titanium-released from dental implant enhances pre-osteoblast adhesion by ROS modulating crucial intracellular pathways.", "journal": "Journal of biomedical materials research. Part A", "date": "2017-11", "authors": "Rossi M C, Bezerra F J B, Silva R A, Crulhas B P, Fernandes C J C, Nascimento A S, Pedrosa V A, Padilha P, Zambuzzi W F", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "28639351", "url": "https://glygen.org/publication/PubMed/28639351" } ] }, { "title": "TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching.", "journal": "Molecular biology of the cell", "date": "2017", "authors": "Plooster M, Menon S, Winkle CC, Urbina FL, Monkiewicz C, Phend KD, Weinberg RJ, Gupton SL", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "28701345", "url": "https://glygen.org/publication/PubMed/28701345" } ] }, { "title": "Regulation of Focal Adhesion Kinase through a Direct Interaction with an Endogenous Inhibitor.", "journal": "Biochemistry", "date": "2017", "authors": "Zak TJ, Koshman YE, Samarel AM, Robia SL", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "28782937", "url": "https://glygen.org/publication/PubMed/28782937" } ] }, { "title": "Daurinol blocks breast and lung cancer metastasis and development by inhibition of focal adhesion kinase (FAK).", "journal": "Oncotarget", "date": "2017-08-22", "authors": "Woo Jong Kyu, Jung Hyun Jin, Park Ji-Youn, Kang Ju-Hee, Lee Byung Il, Shin DongYun, Nho Chu Won, Cho Soo-Young, Seong Je Kyung, Oh Seung Hyun", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "28915654", "url": "https://glygen.org/publication/PubMed/28915654" } ] }, { "title": "A role for ErbB signaling in the induction of reactive astrogliosis.", "journal": "Cell discovery", "date": "2017", "authors": "Chen J, He W, Hu X, Shen Y, Cao J, Wei Z, Luan Y, He L, Jiang F, Tao Y", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "29238610", "url": "https://glygen.org/publication/PubMed/29238610" } ] }, { "title": "Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.", "journal": "Cancer biology & therapy", "date": "2018-04-03", "authors": "Kanteti Rajani, Mirzapoiazova Tamara, Riehm Jacob J, Dhanasingh Immanuel, Mambetsariev Bolot, Wang Jiale, Kulkarni Prakash, Kaushik Garima, Seshacharyulu Parthasarathy, Ponnusamy Moorthy P, Kindler Hedy L, Nasser Mohd W, Batra Surinder K, Salgia Ravi", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "29303405", "url": "https://glygen.org/publication/PubMed/29303405" } ] }, { "title": "Expression of CTGF/CCN2 in response to LPA is stimulated by fibrotic extracellular matrix via the integrin/FAK axis.", "journal": "American journal of physiology. 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"date": "2001", "authors": "Nakamura K, Yano H, Schaefer E, Sabe H", "evidence": [ { "database": "UniProtKB", "id": "P34152", "url": "https://www.uniprot.org/uniprotkb/P34152" }, { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "11420674", "url": "https://glygen.org/publication/PubMed/11420674" } ] }, { "title": "Dual role of Fyn in the regulation of FAK+6,7 by cannabinoids in hippocampus.", "journal": "The Journal of biological chemistry", "date": "2001-10-12", "authors": "Derkinderen P, Toutant M, Kadar\u00e9 G, Ledent C, Parmentier M, Girault J A", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "11468287", "url": "https://glygen.org/publication/PubMed/11468287" } ] }, { "title": "Activation of the lutropin/choriogonadotropin receptor in MA-10 cells leads 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6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.", "journal": "Oncogene", "date": "2013", "authors": "Zheng Y, Gierut J, Wang Z, Miao J, Asara JM, Tyner AL", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "23027128", "url": "https://glygen.org/publication/PubMed/23027128" } ] }, { "title": "Tyrosine kinase BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases.", "journal": "Science signaling", "date": "2013", "authors": "Chen S, Jiang X, Gewinner CA, Asara JM, Simon NI, Cai C, Cantley LC, Balk SP", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "23716717", "url": "https://glygen.org/publication/PubMed/23716717" } ] }, { "title": "A 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Cell physiology", "date": "2015-01-15", "authors": "Rasmussen Line Jee Hartmann, M\u00fcller Helene Steenk\u00e6r Holm, J\u00f8rgensen Bente, Pedersen Stine Falsig, Hoffmann Else Kay", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25377086", "url": "https://glygen.org/publication/PubMed/25377086" } ] }, { "title": "Protein Tyrosine Kinase 6 Regulates UVB-Induced Signaling and Tumorigenesis in Mouse Skin.", "journal": "The Journal of investigative dermatology", "date": "2015", "authors": "Chastkofsky MI, Bie W, Ball-Kell SM, He YY, Tyner AL", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "25938342", "url": "https://glygen.org/publication/PubMed/25938342" } ] }, { "title": "Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland 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activity.", "journal": "Oncotarget", "date": "2016-11-01", "authors": "Kishi Takayuki, Mayanagi Taira, Iwabuchi Sadahiro, Akasaka Toshihide, Sobue Kenji", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "27708220", "url": "https://glygen.org/publication/PubMed/27708220" } ] }, { "title": "Outside-in integrin signalling regulates haematopoietic stem cell function via Periostin-Itgav axis.", "journal": "Nature communications", "date": "2016-12-01", "authors": "Khurana Satish, Schouteden Sarah, Manesia Javed K, Santamaria-Mart\u00ednez Albert, Huelsken Joerg, Lacy-Hulbert Adam, Verfaillie Catherine M", "evidence": [ { "database": "iPTMnet", "id": "P34152", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P34152" } ], "reference": [ { "type": "PubMed", "id": "27905395", "url": "https://glygen.org/publication/PubMed/27905395" } ] }, { "title": "Focal 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