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arcuate nucleus of ob/ob mice under basal conditions.", "journal": "Brain research", "date": "2005", "authors": "Komori T, Morikawa Y, Tamura S, Doi A, Nanjo K, Senba E", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "15925330", "url": "https://glygen.org/publication/PubMed/15925330" } ] }, { "title": "Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation.", "journal": "Life sciences", "date": "2005", "authors": "Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "15982669", "url": "https://glygen.org/publication/PubMed/15982669" } ] }, { "title": "Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 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"Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling.", "journal": "Endocrinology", "date": "2006-09", "authors": "Wang Xiaonan, Hu Zhaoyong, Hu Junping, Du Jie, Mitch William E", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "16777975", "url": "https://glygen.org/publication/PubMed/16777975" } ] }, { "title": "Castration rapidly decreases local insulin-like growth factor-1 levels and inhibits its effects in the ventral prostate in mice.", "journal": "The Prostate", "date": "2006-12-01", "authors": "Ohlson Nina, Bergh Anders, Persson Malin Lindhagen, Wikstr\u00f6m Pernilla", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "16998818", "url": "https://glygen.org/publication/PubMed/16998818" } ] }, { "title": "Retinol-binding protein-4 attenuates insulin-induced phosphorylation of IRS1 and ERK1/2 in primary human adipocytes.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2007", "authors": "Ost A, Danielsson A, Liden M, Eriksson U, Nystrom FH, Stralfors P", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "17575262", "url": "https://glygen.org/publication/PubMed/17575262" } ] }, { "title": "The G/G genotype of a single nucleotide polymorphism at -1066 of c-Jun N-terminal kinase 1 gene (MAPK8) does not affect type 2 diabetes susceptibility despite the specific binding of AP2alpha.", "journal": "Clinical endocrinology", "date": "2008", "authors": "Osawa H, Yamada K, Tabara Y, Ochi M, Onuma H, Nishida W, Shimizu I, Kawamoto R, Fujii Y, Miki T, Ohashi J, Makino H", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "18036196", "url": "https://glygen.org/publication/PubMed/18036196" } ] }, { "title": "Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Emanuelli B, Eberle D, Suzuki R, Kahn CR", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "18296638", "url": "https://glygen.org/publication/PubMed/18296638" } ] }, { "title": "Chromium supplementation enhances insulin signalling in skeletal muscle of obese KK/HlJ diabetic mice.", "journal": "Diabetes, obesity & metabolism", "date": "2009", "authors": "Chen WY, Chen CJ, Liu CH, Mao FC", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "18721257", "url": "https://glygen.org/publication/PubMed/18721257" } ] }, { "title": "Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle.", "journal": "Diabetes", "date": "2008", "authors": "Nieto-Vazquez I, Fernandez-Veledo S, de Alvaro C, Lorenzo M", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "18796617", "url": "https://glygen.org/publication/PubMed/18796617" } ] }, { "title": "Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity.", "journal": "PloS one", "date": "2009", "authors": "Bonkowski MS, Dominici FP, Arum O, Rocha JS, Al Regaiey KA, Westbrook R, Spong A, Panici J, Masternak MM, Kopchick JJ, Bartke A", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "19234595", "url": "https://glygen.org/publication/PubMed/19234595" } ] }, { "title": "Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.", "journal": "Molecular and cellular biology", "date": "2009", "authors": "Standen CL, Kennedy NJ, Flavell RA, Davis RJ", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "19564410", "url": "https://glygen.org/publication/PubMed/19564410" } ] }, { "title": "Degradation of IRS1 leads to impaired glucose uptake in adipose tissue of the type 2 diabetes mouse model TALLYHO/Jng.", "journal": "The Journal of endocrinology", "date": "2009", "authors": "Wang Y, Nishina PM, Naggert JK", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "19587264", "url": "https://glygen.org/publication/PubMed/19587264" } ] }, { "title": "Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.", "journal": "Endocrinology", "date": "2010-04", "authors": "Coll Teresa, Alvarez-Guardia David, Barroso Emma, G\u00f3mez-Foix Anna Maria, Palomer Xavier, Laguna Juan C, V\u00e1zquez-Carrera Manuel", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "20185762", "url": "https://glygen.org/publication/PubMed/20185762" } ] }, { "title": "Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine.", "journal": "American journal of physiology. Endocrinology and metabolism", "date": "2010", "authors": "Lang CH, Frost RA, Bronson SK, Lynch CJ, Vary TC", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "20388826", "url": "https://glygen.org/publication/PubMed/20388826" } ] }, { "title": "Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.", "journal": "American journal of physiology. Endocrinology and metabolism", "date": "2011", "authors": "Latreille M, Laberge MK, Bourret G, Yamani L, Larose L", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "20587749", "url": "https://glygen.org/publication/PubMed/20587749" } ] }, { "title": "Phenylmethimazole blocks palmitate-mediated induction of inflammatory cytokine pathways in 3T3L1 adipocytes and RAW 264.7 macrophages.", "journal": "The Journal of endocrinology", "date": "2010", "authors": "McCall KD, Holliday D, Dickerson E, Wallace B, Schwartz AL, Schwartz C, Lewis CJ, Kohn LD, Schwartz FL", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "20813836", "url": "https://glygen.org/publication/PubMed/20813836" } ] }, { "title": "p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance.", "journal": "Diabetes", "date": "2011", "authors": "Hemi R, Yochananov Y, Barhod E, Kasher-Meron M, Karasik A, Tirosh A, Kanety H", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "21386087", "url": "https://glygen.org/publication/PubMed/21386087" } ] }, { "title": "Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance.", "journal": "Journal of lipid research", "date": "2011", "authors": "Han MS, Lim YM, Quan W, Kim JR, Chung KW, Kang M, Kim S, Park SY, Han JS, Park SY, Cheon HG, Dal Rhee S, Park TS, Lee MS", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "21447485", "url": "https://glygen.org/publication/PubMed/21447485" } ] }, { "title": "Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism.", "journal": "PloS one", "date": "2011", "authors": "Macotela Y, Emanuelli B, Bang AM, Espinoza DO, Boucher J, Beebe K, Gall W, Kahn CR", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "21731668", "url": "https://glygen.org/publication/PubMed/21731668" } ] }, { "title": "[LRP16 gene causes insulin resistance in C2-C12 cells by inhibiting the IRS-1 signaling and the transcriptional activity of peroxisome proliferator actived receptor gamma].", "journal": "Zhonghua yi xue za zhi", "date": "2011", "authors": "Zang L, Mu YM, Lu ZH, Xue B, Ma XL, Yang GQ, Ba JM, Dou JT, Lu JM", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "21756814", "url": "https://glygen.org/publication/PubMed/21756814" } ] }, { "title": "Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.", "journal": "Journal of agricultural and food chemistry", "date": "2012", "authors": "Deng YT, Chang TW, Lee MS, Lin JK", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22191431", "url": "https://glygen.org/publication/PubMed/22191431" } ] }, { "title": "Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice.", "journal": "Gastroenterology", "date": "2012", "authors": "Liu J, Zhou L, Xiong K, Godlewski G, Mukhopadhyay B, Tam J, Yin S, Gao P, Shan X, Pickel J, Bataller R, O'Hare J, Scherer T, Buettner C, Kunos G", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22307032", "url": "https://glygen.org/publication/PubMed/22307032" } ] }, { "title": "Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production.", "journal": "American journal of physiology. Endocrinology and metabolism", "date": "2012", "authors": "Lin L, Pang W, Chen K, Wang F, Gengler J, Sun Y, Tong Q", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22454293", "url": "https://glygen.org/publication/PubMed/22454293" } ] }, { "title": "Genome-wide analysis of glucocorticoid receptor-binding sites in myotubes identifies gene networks modulating insulin signaling.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "Kuo T, Lew MJ, Mayba O, Harris CA, Speed TP, Wang JC", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22733784", "url": "https://glygen.org/publication/PubMed/22733784" } ] }, { "title": "Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice.", "journal": "Diabetologia", "date": "2012", "authors": "Carvalho BM, Guadagnini D, Tsukumo DML, Schenka AA, Latuf-Filho P, Vassallo J, Dias JC, Kubota LT, Carvalheira JBC, Saad MJA", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22828956", "url": "https://glygen.org/publication/PubMed/22828956" } ] }, { "title": "Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice.", "journal": "Diabetologia", "date": "2012", "authors": "Henstridge DC, Bruce CR, Pang CP, Lancaster GI, Allen TL, Estevez E, Gardner T, Weir JM, Meikle PJ, Lam KSL, Xu A, Fujii N, Goodyear LJ, Febbraio MA", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22832498", "url": "https://glygen.org/publication/PubMed/22832498" } ] }, { "title": "Fraction from wax apple [Syzygium samarangense (Blume) Merrill and Perry] fruit extract ameliorates insulin resistance via modulating insulin signaling and inflammation pathway in tumor necrosis factor alpha-treated FL83B mouse hepatocytes.", "journal": "International journal of molecular sciences", "date": "2012", "authors": "Shen SC, Chang WC, Chang CL", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "22942720", "url": "https://glygen.org/publication/PubMed/22942720" } ] }, { "title": "Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice.", "journal": "Endocrinology", "date": "2012", "authors": "Carvalho-Filho MA, Carvalho BM, Oliveira AG, Guadagnini D, Ueno M, Dias MM, Tsukumo DM, Hirabara 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"date": "2014", "authors": "Pereira BC, Pauli JR, De Souza CT, Ropelle ER, Cintra DE, Freitas EC, da Silva AS", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "24002347", "url": "https://glygen.org/publication/PubMed/24002347" } ] }, { "title": "IRS1Ser(3)(0)(7) phosphorylation does not mediate mTORC1-induced insulin resistance.", "journal": "Biochemical and biophysical research communications", "date": "2014", "authors": "Herrema H, Lee J, Zhou Y, Copps KD, White MF, Ozcan U", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "24333417", "url": "https://glygen.org/publication/PubMed/24333417" } ] }, { "title": "Co-activation of nuclear factor-kappaB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Madonna R, Geng YJ, Bolli R, Rokosh G, Ferdinandy P, Patterson C, De Caterina R", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "24855642", "url": "https://glygen.org/publication/PubMed/24855642" } ] }, { "title": "beta1-adrenergic receptor stimulation by agonist Compound 49b restores insulin receptor signal transduction in vivo.", "journal": "Molecular vision", "date": "2014", "authors": "Jiang Y, Zhang Q, Ye EA, Steinle JJ", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "24966659", "url": "https://glygen.org/publication/PubMed/24966659" } ] }, { "title": "Altered hepatic insulin signalling in male offspring of obese mice.", "journal": "Journal of developmental origins of health and disease", "date": "2010", "authors": "Martin-Gronert MS, Fernandez-Twinn DS, Poston L, Ozanne SE", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "25141786", "url": "https://glygen.org/publication/PubMed/25141786" } ] }, { "title": "Hypochlorous acid via peroxynitrite activates protein kinase Ctheta and insulin resistance in adipocytes.", "journal": "Journal of molecular endocrinology", "date": "2015", "authors": "Zhou J, Wang Q, Ding Y, Zou MH", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "25381390", "url": "https://glygen.org/publication/PubMed/25381390" } ] }, { "title": "Role of Mig-6 in hepatic glucose metabolism.", "journal": "Journal of diabetes", "date": "2016", "authors": "Yoo JY, Kim TH, Kong S, Lee JH, Choi W, Kim KS, Kim HJ, Jeong JW, Ku BJ", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "25594850", "url": "https://glygen.org/publication/PubMed/25594850" } ] }, { "title": "Titanium dioxide nanoparticles increase plasma glucose via reactive oxygen species-induced insulin resistance in mice.", "journal": "Journal of applied toxicology : JAT", "date": "2015", "authors": "Hu H, Guo Q, Wang C, Ma X, He H, Oh Y, Feng Y, Wu Q, Gu N", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "25826740", "url": "https://glygen.org/publication/PubMed/25826740" } ] }, { "title": "High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity.", "journal": "PloS one", "date": "2015", "authors": "Liu Z, Patil IY, Jiang T, Sancheti H, Walsh JP, Stiles BL, Yin F, Cadenas E", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26023930", "url": "https://glygen.org/publication/PubMed/26023930" } ] }, { "title": "Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway.", "journal": "The Journal of biological chemistry", "date": "2015", "authors": "Tao W, Wu J, Xie BX, Zhao YY, Shen N, Jiang S, Wang XX, Xu N, Jiang C, Chen S, Gao X, Xue B, Li CJ", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26112408", "url": "https://glygen.org/publication/PubMed/26112408" } ] }, { "title": "DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression.", "journal": "Scientific reports", "date": "2015", "authors": "Abu-Farha M, Cherian P, Al-Khairi I, Tiss A, Khadir A, Kavalakatt S, Warsame S, Dehbi M, Behbehani K, Abubaker J", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26400768", "url": "https://glygen.org/publication/PubMed/26400768" } ] }, { "title": "Acute Treatment of Resveratrol Alleviates Doxorubicin-Induced Myotoxicity in Aged Skeletal Muscle Through SIRT1-Dependent Mechanisms.", "journal": "The journals of gerontology. Series A, Biological sciences and medical sciences", "date": "2016", "authors": "Sin TK, Tam BT, Yu AP, Yip SP, Yung BY, Chan LW, Wong CS, Rudd JA, Siu PM", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26450947", "url": "https://glygen.org/publication/PubMed/26450947" } ] }, { "title": "Mitochondrial-generated ROS down regulates insulin signaling via activation of the p38MAPK stress response pathway.", "journal": "Molecular and cellular endocrinology", "date": "2016", "authors": "Al-Lahham R, Deford JH, Papaconstantinou J", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26454089", "url": "https://glygen.org/publication/PubMed/26454089" } ] }, { "title": "IGF-1 mediated phosphorylation of specific IRS-1 serines in Ames dwarf fibroblasts is associated with longevity.", "journal": "Oncotarget", "date": "2015", "authors": "Papaconstantinou J, Hsieh CC", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26474286", "url": "https://glygen.org/publication/PubMed/26474286" } ] }, { "title": "Protein phosphatase 4 (PP4) functions as a critical regulator in tumor necrosis factor (TNF)-alpha-induced hepatic insulin resistance.", "journal": "Scientific reports", "date": "2015", "authors": "Zhao H, Huang X, Jiao J, Zhang H, Liu J, Qin W, Meng X, Shen T, Lin Y, Chu J, Li J", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26666849", "url": "https://glygen.org/publication/PubMed/26666849" } ] }, { "title": "Inhibition of Protein Tyrosine Phosphatase 1B Improves IGF-I Receptor Signaling and Protects Against Inflammation-Induced Gliosis in the Retina.", "journal": "Investigative ophthalmology & visual science", "date": "2015", "authors": "Arroba AI, Valverde AM", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26720454", "url": "https://glygen.org/publication/PubMed/26720454" } ] }, { "title": "High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo.", "journal": "PloS one", "date": "2016", "authors": "Zhi L, Yuzhang Z, Tianliang H, Hisatome I, Yamamoto T, Jidong C", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26836389", "url": "https://glygen.org/publication/PubMed/26836389" } ] }, { "title": "Hepatocyte TRAF3 promotes liver steatosis and systemic insulin resistance through targeting TAK1-dependent signalling.", "journal": "Nature communications", "date": "2016-02-17", "authors": "Wang Pi-Xiao, Zhang Xiao-Jing, Luo Pengcheng, Jiang Xi, Zhang Peng, Guo Junhong, Zhao Guang-Nian, Zhu Xueyong, Zhang Yan, Yang Sijun, Li Hongliang", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "26882989", "url": "https://glygen.org/publication/PubMed/26882989" } ] }, { "title": "Inhibition of M1 macrophage activation in adipose tissue by berberine improves insulin resistance.", "journal": "Life sciences", "date": "2016", "authors": "Ye L, Liang S, Guo C, Yu X, Zhao J, Zhang H, Shang W", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "27702567", "url": "https://glygen.org/publication/PubMed/27702567" } ] }, { "title": "Airborne PM2.5-Induced Hepatic Insulin Resistance by Nrf2/JNK-Mediated Signaling Pathway.", "journal": "International journal of environmental research and public health", "date": "2017", "authors": "Xu J, Zhang W, Lu Z, Zhang F, Ding W", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "28708100", "url": "https://glygen.org/publication/PubMed/28708100" } ] }, { "title": "Permethrin decreased insulin-stimulated AKT phosphorylation dependent on extracellular signal-regulated kinase-1 (ERK), but not AMP-activated protein kinase alpha (AMPKalpha), in C2C12 myotubes.", "journal": "Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association", "date": "2017", "authors": "Sun Q, Peng Y, Qi W, Kim Y, Clark JM, Kim D, Park Y", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" 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Nata\u0161a, Gligorovska Ljupka, Ignjatovi\u0107 Djurdjica, Tomi\u0107 Mirko, Mati\u0107 Gordana", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "28919555", "url": "https://glygen.org/publication/PubMed/28919555" } ] }, { "title": "miRNA15a regulates insulin signal transduction in the retinal vasculature.", "journal": "Cellular signalling", "date": "2018-04", "authors": "Jiang Youde, Liu Li, Steinle Jena J", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "29339083", "url": "https://glygen.org/publication/PubMed/29339083" } ] }, { "title": "The effect of noise exposure on insulin sensitivity in mice may be mediated by the JNK/IRS1 pathway.", "journal": "Environmental health and preventive medicine", "date": "2018-02-12", "authors": "Liu Lijie, Fang Cong, Yang Jing, Zhang Hongyu, Huang Yi, Xuan Chuanying, Wang Yongfang, Li Shengwei, Sha Jun, Zha Mingming, Guo Min", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "29433422", "url": "https://glygen.org/publication/PubMed/29433422" } ] }, { "title": "Vascular dysfunction in obese diabetic db/db mice involves the interplay between aldosterone/mineralocorticoid receptor and Rho kinase signaling.", "journal": "Scientific reports", "date": "2018", "authors": "Nguyen Dinh Cat A, Callera GE, Friederich-Persson M, Sanchez A, Dulak-Lis MG, Tsiropoulou S, Montezano AC, He Y, Briones AM, Jaisser F, Touyz RM", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "29440699", "url": "https://glygen.org/publication/PubMed/29440699" } ] }, { "title": "Toll-like receptor 4 regulates insulin signal transduction in retinal Muller cells.", "journal": "Growth factors (Chur, Switzerland)", "date": "2017", "authors": "Liu L, Steinle JJ", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "29490521", "url": "https://glygen.org/publication/PubMed/29490521" } ] }, { "title": "TRIM31 Deficiency Is Associated with Impaired Glucose Metabolism and Disrupted Gut Microbiota in Mice.", "journal": "Frontiers in physiology", "date": "2018", "authors": "Cheng J, Xue F, Zhang M, Cheng C, Qiao L, Ma J, Sui W, Xu X, Gao C, Hao P, Zhang M, Zhang Y", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "29497383", "url": "https://glygen.org/publication/PubMed/29497383" } ] }, { "title": "The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation.", "journal": "Molecular neurobiology", "date": "2019", "authors": "Sposato V, Canu N, Fico E, Fusco S, Bolasco G, Ciotti MT, Spinelli M, Mercanti D, Grassi C, Triaca V, Calissano P", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": "PubMed", "id": "29736736", "url": "https://glygen.org/publication/PubMed/29736736" } ] }, { "title": "Metformin treatment ameliorates diabetes-associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1.", "journal": "FEBS open bio", "date": "2018", "authors": "Tanokashira D, Kurata E, Fukuokaya W, Kawabe K, Kashiwada M, Takeuchi H, Nakazato M, Taguchi A", "evidence": [ { "database": "iPTMnet", "id": "P35569", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P35569" } ], "reference": [ { "type": 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