[ { "title": "The neural cell adhesion molecule L1: genomic organisation and differential splicing is conserved between man and the pufferfish Fugu.", "journal": "Gene", "date": "1998", "authors": "Coutelle O, Nyakatura G, Taudien S, Elgar G, Brenner S, Platzer M, Drescher B, Jouet M, Kenwrick S, Rosenthal A", "reference": { "type": "PubMed", "id": "9479034", "url": "https://pubmed.ncbi.nlm.nih.gov/9479034" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P32004-1", "protein_name": "Neural cell adhesion molecule L1", "gene_name": "L1CAM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P32004", "url": "https://www.uniprot.org/uniprotkb/P32004" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9479034", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"O75676-1", "protein_name": "Ribosomal protein S6 kinase alpha-4", "gene_name": "RPS6KA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15349-1", "protein_name": "Ribosomal protein S6 kinase alpha-2", "gene_name": "RPS6KA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BVA1-1", "protein_name": "Tubulin beta-2B chain", "gene_name": "TUBB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26038-1", "protein_name": "Moesin", "gene_name": "MSN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49757-1", "protein_name": "Protein numb homolog", "gene_name": "NUMB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK32-1", "protein_name": "Ribosomal protein S6 kinase alpha-6", "gene_name": "RPS6KA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95239-1", "protein_name": "Chromosome-associated kinesin KIF4A", "gene_name": "KIF4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2VIQ3-1", "protein_name": "Chromosome-associated kinesin KIF4B", "gene_name": "KIF4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15418-1", "protein_name": "Ribosomal protein S6 kinase alpha-1", "gene_name": "RPS6KA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0MZ66-1", "protein_name": "Shootin-1", "gene_name": "SHTN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35241-1", "protein_name": "Radixin", "gene_name": "RDX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15311-1", "protein_name": "Ezrin", "gene_name": "EZR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16555-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "DPYSL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P32004", "url": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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immunoglobulin-like domain 2 of the cell adhesion molecule L1.", "journal": "Journal of neurochemistry", "date": "1998", "authors": "Zhao X, Yip PM, Siu CH", "reference": { "type": "PubMed", "id": "9721721", "url": "https://pubmed.ncbi.nlm.nih.gov/9721721" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P32004-1", "protein_name": "Neural cell adhesion molecule L1", "gene_name": "L1CAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P49757-1", "protein_name": "Protein numb homolog", "gene_name": "NUMB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK32-1", "protein_name": "Ribosomal protein S6 kinase alpha-6", "gene_name": "RPS6KA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95239-1", "protein_name": "Chromosome-associated kinesin KIF4A", "gene_name": "KIF4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2VIQ3-1", "protein_name": "Chromosome-associated kinesin KIF4B", "gene_name": "KIF4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A 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"gene_name": "SHTN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35241-1", "protein_name": "Radixin", "gene_name": "RDX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15311-1", "protein_name": "Ezrin", "gene_name": "EZR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16555-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "DPYSL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P32004", "url": "https://www.uniprot.org/uniprotkb/P32004" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9721721", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 48 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The site of a missense mutation in the extracellular Ig or FN domains of L1CAM influences infant mortality and the severity of X linked hydrocephalus.", "journal": "Journal of medical genetics", "date": "1998", "authors": "Michaelis RC, Du YZ, Schwartz CE", "reference": { "type": "PubMed", "id": "9832035", "url": "https://pubmed.ncbi.nlm.nih.gov/9832035" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P32004-1", "protein_name": "Neural cell adhesion molecule L1", "gene_name": "L1CAM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P32004", "url": "https://www.uniprot.org/uniprotkb/P32004" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9832035", "abstract": "", "glycosylation": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5ZJJ2-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex 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"protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11080452", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 81 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Polarity of human replication protein A binding to DNA.", "journal": "Nucleic acids research", "date": "2001", "authors": "Kolpashchikov DM, Khodyreva SN, Khlimankov DY, Wold MS, Favre A, Lavrik OI", "reference": { "type": "PubMed", "id": "11139606", "url": "https://pubmed.ncbi.nlm.nih.gov/11139606" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11139606", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.", "journal": "Cell", "date": "2001", "authors": "Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM", "reference": { "type": "PubMed", "id": "11301010", "url": "https://pubmed.ncbi.nlm.nih.gov/11301010" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 52, "end_pos": 52, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes ATPase and dsDNA helicase activities, preventing ability to unfold DNA-protein cross-links. Does not unwind G-quadruplex DNA. Disrupts BRCA1-mediated double-strand break repair.", "evidence": [ { "database": "UniProtKB", "id": "Q9BX63", "url": "https://www.uniprot.org/uniprotkb/Q9BX63" }, { "database": "PubMed", "id": "16116421", "url": "https://pubmed.ncbi.nlm.nih.gov/16116421" }, { "database": "PubMed", "id": "14983014", "url": "https://pubmed.ncbi.nlm.nih.gov/14983014" }, { "database": "PubMed", "id": "36608669", "url": "https://pubmed.ncbi.nlm.nih.gov/36608669" }, { "database": "PubMed", "id": "11301010", "url": "https://pubmed.ncbi.nlm.nih.gov/11301010" }, { "database": "PubMed", "id": "18426915", "url": "https://pubmed.ncbi.nlm.nih.gov/18426915" } ], "uniprot_canonical_ac": "Q9BX63-1" } ], "record_id": "pubmed.11301010", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Homologous recombinational repair of DNA ensures mammalian chromosome stability.", "journal": "Mutation research", "date": "2001", "authors": "Thompson LH, Schild D", "reference": { "type": "PubMed", "id": "11376695", "url": "https://pubmed.ncbi.nlm.nih.gov/11376695" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", 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"gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 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"gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle 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Reduces phosphorylation and impairs activation by hydroxyurea and ionizing radiation. 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12545175", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2003", "authors": "Bermudez VP, Lindsey-Boltz LA, Cesare AJ, Maniwa Y, Griffith JD, Hurwitz J, Sancar A", "reference": { "type": "PubMed", "id": "12578958", "url": "https://pubmed.ncbi.nlm.nih.gov/12578958" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBD5-1", "protein_name": "Origin recognition complex subunit 3", "gene_name": "ORC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13415-1", "protein_name": "Origin recognition complex subunit 1", "gene_name": "ORC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13416-1", "protein_name": "Origin recognition complex subunit 2", "gene_name": "ORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L590-1", "protein_name": "Protein MCM10 homolog", "gene_name": "MCM10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00311-1", "protein_name": "Cell division cycle 7-related protein kinase", "gene_name": "CDC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBU7-1", "protein_name": "Protein DBF4 homolog A", "gene_name": "DBF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43913-1", "protein_name": "Origin recognition complex subunit 5", "gene_name": "ORC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25205-1", "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33992-1", "protein_name": "DNA replication licensing factor MCM5", "gene_name": "MCM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43929-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "ORC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99741-1", "protein_name": "DNA replication factor CDC6", "gene_name": "CDC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5N6-1", "protein_name": "Origin recognition complex subunit 6", "gene_name": "ORC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33991-1", "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJA3-1", "protein_name": "DNA helicase MCM8", "gene_name": "MCM8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30304-1", "protein_name": "M-phase inducer phosphatase 1", "gene_name": "CDC25A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30307-1", "protein_name": "M-phase inducer phosphatase 3", "gene_name": "CDC25C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12578958", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 100 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.", "journal": "Science (New York, N.Y.)", "date": "2003", "authors": "Zou L, Elledge SJ", "reference": { "type": "PubMed", "id": "12791985", "url": "https://pubmed.ncbi.nlm.nih.gov/12791985" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBD5-1", "protein_name": "Origin recognition complex subunit 3", "gene_name": "ORC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13415-1", "protein_name": "Origin recognition complex subunit 1", "gene_name": "ORC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13416-1", "protein_name": "Origin recognition complex subunit 2", "gene_name": "ORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L590-1", "protein_name": "Protein MCM10 homolog", "gene_name": "MCM10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00311-1", "protein_name": "Cell division cycle 7-related protein kinase", "gene_name": "CDC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBU7-1", "protein_name": "Protein DBF4 homolog A", "gene_name": "DBF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43913-1", "protein_name": "Origin recognition complex subunit 5", "gene_name": "ORC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04377-1", "protein_name": "DNA damage checkpoint protein LCD1", "gene_name": "LCD1", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25205-1", "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33992-1", "protein_name": "DNA replication licensing factor MCM5", "gene_name": "MCM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B 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"uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5N6-1", "protein_name": "Origin recognition complex subunit 6", "gene_name": "ORC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33991-1", "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJA3-1", "protein_name": "DNA helicase MCM8", "gene_name": "MCM8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30304-1", "protein_name": "M-phase inducer phosphatase 1", "gene_name": "CDC25A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30307-1", "protein_name": "M-phase inducer phosphatase 3", "gene_name": "CDC25C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12791985", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": 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Mol. Biol.", "date": "2003", "authors": "Gotter AL", "reference": { "type": "PubMed", "id": "12875843", "url": "https://pubmed.ncbi.nlm.nih.gov/12875843" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q91WA1-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "Tipin", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R1X4-1", "protein_name": "Protein timeless homolog", "gene_name": "Timeless", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12875843", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": 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Impairs the interaction with BRCA1.", "evidence": [ { "database": "UniProtKB", "id": "Q9BX63", "url": "https://www.uniprot.org/uniprotkb/Q9BX63" }, { "database": "PubMed", "id": "14576433", "url": "https://pubmed.ncbi.nlm.nih.gov/14576433" } ], "uniprot_canonical_ac": "Q9BX63-1" }, { "start_pos": 992, "end_pos": 992, "sequence_org": "T", "sequence_mut": "A", "comment": "Does not affect the interaction with BRCA1.", "evidence": [ { "database": "UniProtKB", "id": "Q9BX63", "url": "https://www.uniprot.org/uniprotkb/Q9BX63" }, { "database": "PubMed", "id": "14576433", "url": "https://pubmed.ncbi.nlm.nih.gov/14576433" } ], "uniprot_canonical_ac": "Q9BX63-1" }, { "start_pos": 993, "end_pos": 993, "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes phosphorylation of S-990. 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.", "journal": "Annual review of biochemistry", "date": "2004", "authors": "Sancar A, Lindsey-Boltz LA, Unsal-Kacmaz K, Linn S", "reference": { "type": "PubMed", "id": "15189136", "url": "https://pubmed.ncbi.nlm.nih.gov/15189136" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15189136", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2004", "authors": "Sorensen CS, Syljuasen RG, Lukas J, Bartek J", "reference": { "type": "PubMed", "id": "15190204", "url": "https://pubmed.ncbi.nlm.nih.gov/15190204" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBD5-1", "protein_name": "Origin recognition complex subunit 3", "gene_name": "ORC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13415-1", "protein_name": "Origin recognition complex subunit 1", "gene_name": "ORC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13416-1", "protein_name": "Origin recognition complex subunit 2", "gene_name": "ORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L590-1", "protein_name": "Protein MCM10 homolog", "gene_name": "MCM10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00311-1", "protein_name": "Cell division cycle 7-related protein kinase", "gene_name": "CDC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBU7-1", "protein_name": "Protein DBF4 homolog A", "gene_name": "DBF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43913-1", "protein_name": "Origin recognition complex subunit 5", "gene_name": "ORC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": 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"uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16148040", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.", "journal": "Cancer cell", "date": "2005", "authors": "Litman R, Peng M, Jin Z, Zhang F, Zhang J, Powell S, Andreassen PR, Cantor SB", "reference": { "type": "PubMed", "id": "16153896", "url": "https://pubmed.ncbi.nlm.nih.gov/16153896" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16153896", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks.", "journal": "Nature cell biology", "date": "2006", "authors": "Jazayeri A, Falck J, Lukas C, Bartek J, Smith GC, Lukas J, Jackson SP", "reference": { "type": "PubMed", "id": "16327781", "url": "https://pubmed.ncbi.nlm.nih.gov/16327781" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBD5-1", "protein_name": "Origin recognition complex subunit 3", "gene_name": "ORC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13415-1", "protein_name": "Origin recognition complex subunit 1", "gene_name": "ORC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13416-1", "protein_name": "Origin recognition complex subunit 2", "gene_name": "ORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L590-1", "protein_name": "Protein MCM10 homolog", "gene_name": "MCM10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00311-1", "protein_name": "Cell division cycle 7-related protein kinase", "gene_name": "CDC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBU7-1", "protein_name": "Protein DBF4 homolog A", "gene_name": "DBF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43913-1", "protein_name": "Origin recognition complex subunit 5", "gene_name": "ORC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25205-1", "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33992-1", "protein_name": "DNA replication licensing factor MCM5", "gene_name": "MCM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43929-1", "protein_name": "Origin recognition complex subunit 4", "gene_name": "ORC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99741-1", "protein_name": "DNA replication factor CDC6", "gene_name": "CDC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5N6-1", "protein_name": "Origin recognition complex subunit 6", "gene_name": "ORC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33991-1", "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJA3-1", "protein_name": "DNA helicase MCM8", "gene_name": "MCM8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30304-1", "protein_name": "M-phase inducer phosphatase 1", "gene_name": "CDC25A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30307-1", "protein_name": "M-phase inducer phosphatase 3", "gene_name": "CDC25C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16327781", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 100 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.", "journal": "Current biology : CB", "date": "2006", "authors": "Smits VA, Reaper PM, Jackson SP", "reference": { "type": "PubMed", "id": "16360315", "url": "https://pubmed.ncbi.nlm.nih.gov/16360315" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TopBP1 activates the ATR-ATRIP complex.", "journal": "Cell", "date": "2006", "authors": "Kumagai A, Lee J, Yoo HY, Dunphy WG", "reference": { "type": "PubMed", "id": "16530042", "url": "https://pubmed.ncbi.nlm.nih.gov/16530042" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16530042", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress.", "journal": "Molecular cell", "date": "2006", "authors": "Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, Elledge SJ, Li L", "reference": { "type": "PubMed", "id": "16885023", "url": "https://pubmed.ncbi.nlm.nih.gov/16885023" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", 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"protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16885023", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Yoshizawa-Sugata N, Masai H", "reference": { "type": "PubMed", "id": "17102137", "url": "https://pubmed.ncbi.nlm.nih.gov/17102137" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17102137", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2006", "authors": "Chou DM, Elledge SJ", "reference": { "type": "PubMed", "id": "17116885", "url": "https://pubmed.ncbi.nlm.nih.gov/17116885" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17116885", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.", "journal": "J. Mol. Biol.", "date": "2007", "authors": "Gotter AL, Suppa C, Emanuel BS", "reference": { "type": "PubMed", "id": "17141802", "url": "https://pubmed.ncbi.nlm.nih.gov/17141802" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q61171-1", "protein_name": "Peroxiredoxin-2", "gene_name": "Prdx2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q62193-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "Rpa2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P32119-1", "protein_name": "Peroxiredoxin-2", "gene_name": "PRDX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q91WA1-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "Tipin", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17141802", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement.", "journal": "Molecular and cellular biology", "date": "2007-04", "authors": "Unsal-Ka\u00e7maz Keziban, Chastain Paul D, Qu Ping-Ping, Minoo Parviz, Cordeiro-Stone Marila, Sancar Aziz, Kaufmann William K", "reference": { "type": "PubMed", "id": "17296725", "url": "https://pubmed.ncbi.nlm.nih.gov/17296725" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17296725", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1.", "journal": "Genes & development", "date": "2007", "authors": "Delacroix S, Wagner JM, Kobayashi M, Yamamoto K, Karnitz LM", "reference": { "type": "PubMed", "id": "17575048", "url": "https://pubmed.ncbi.nlm.nih.gov/17575048" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5ZJJ2-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P53033-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { 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"protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71UI9-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BWT6-1", "protein_name": "Meiotic nuclear division protein 1 homolog", "gene_name": "MND1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43196-1", "protein_name": "MutS protein homolog 5", "gene_name": "MSH5-SAPCD1; MSH5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40692-1", "protein_name": "DNA mismatch repair protein Mlh1", "gene_name": "MLH1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 326, "end_pos": 326, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99708", "url": "https://www.uniprot.org/uniprotkb/Q99708" }, { "database": "PubMed", "id": "17965729", 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"kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99708", "url": "https://www.uniprot.org/uniprotkb/Q99708" }, { "database": "PubMed", "id": "17965729", "url": "https://pubmed.ncbi.nlm.nih.gov/17965729" }, { "database": "iPTMnet", "id": "Q99708", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99708" }, { "database": "PubMed", "id": "17525332", "url": "https://pubmed.ncbi.nlm.nih.gov/17525332" } ], "site_lbl": "Ser679", "uniprot_canonical_ac": "Q99708-1" } ], "record_id": "pubmed.17965729", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 108 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Chen L, Nievera CJ, Lee AY, Wu X", "reference": { "type": "PubMed", "id": "18171670", "url": "https://pubmed.ncbi.nlm.nih.gov/18171670" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": 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{ "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends.", "journal": "Cell", "date": "2008", "authors": "Zhu Z, Chung WH, Shim EY, Lee SE, Ira G", "reference": { "type": "PubMed", "id": "18805091", "url": "https://pubmed.ncbi.nlm.nih.gov/18805091" }, 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"uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", 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"gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DNA helicases Sgs1 and BLM promote DNA double-strand break resection.", "journal": "Genes & development", "date": "2008", "authors": "Gravel S, Chapman JR, Magill C, Jackson SP", "reference": { "type": "PubMed", "id": "18923075", "url": "https://pubmed.ncbi.nlm.nih.gov/18923075" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18923075", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Nimonkar AV, Ozsoy AZ, Genschel J, Modrich P, Kowalczykowski SC", "reference": { "type": "PubMed", "id": "18971343", "url": "https://pubmed.ncbi.nlm.nih.gov/18971343" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18971343", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.", "journal": "Nature", "date": "2009", "authors": "Yun MH, Hiom K", "reference": { "type": "PubMed", "id": "19357644", "url": "https://pubmed.ncbi.nlm.nih.gov/19357644" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49916-1", "protein_name": "DNA ligase 3", "gene_name": "LIG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UGN5-1", "protein_name": "Poly [ADP-ribose] polymerase 2", "gene_name": "PARP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39748-1", "protein_name": "Flap endonuclease 1", "gene_name": "FEN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18887-1", "protein_name": "DNA repair protein XRCC1", "gene_name": "XRCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51587-1", "protein_name": "Breast cancer type 2 susceptibility protein", "gene_name": "BRCA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75417-1", "protein_name": "DNA polymerase theta", "gene_name": "POLQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19357644", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 88 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Suhasini AN, Sommers JA, Mason AC, Voloshin ON, Camerini-Otero RD, Wold MS, Brosh RM Jr", "reference": { "type": "PubMed", "id": "19419957", "url": "https://pubmed.ncbi.nlm.nih.gov/19419957" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19419957", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The many facets of the Tim-Tipin protein families' roles in chromosome biology.", "journal": "Cell Cycle", "date": "2010", "authors": "McFarlane Ramsay J, Mian Saira, Dalgaard Jacob Z", "reference": { "type": "PubMed", "id": "20139726", "url": "https://pubmed.ncbi.nlm.nih.gov/20139726" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20139726", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination.", "journal": "Nature structural & molecular biology", "date": "2010", "authors": "Lee DH, Pan Y, Kanner S, Sung P, Borowiec JA, Chowdhury D", "reference": { "type": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06609-1", "protein_name": "DNA repair protein RAD51 homolog 1", "gene_name": "RAD51", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", 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"gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 103, "end_pos": 103, "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on RPA2-binding; loss of PPP4C-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9NY27", "url": "https://www.uniprot.org/uniprotkb/Q9NY27" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" } ], "uniprot_canonical_ac": "Q9NY27-1" }, { "start_pos": 106, "end_pos": 106, "sequence_org": "E", "sequence_mut": "A", "comment": "No effect on RPA2-binding, nor on PPP4C-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9NY27", "url": "https://www.uniprot.org/uniprotkb/Q9NY27" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" } ], "uniprot_canonical_ac": "Q9NY27-1" }, { "start_pos": 99, "end_pos": 99, "sequence_org": "F", "sequence_mut": "A", "comment": "No effect on RPA2-binding; decrease in PPP4C-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q9NY27", "url": "https://www.uniprot.org/uniprotkb/Q9NY27" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" } ], "uniprot_canonical_ac": "Q9NY27-1" }, { "start_pos": 82, "end_pos": 82, "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of activity.", "evidence": [ { "database": "UniProtKB", "id": "P60510", "url": "https://www.uniprot.org/uniprotkb/P60510" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" } ], "uniprot_canonical_ac": "P60510-1" }, { "start_pos": 23, "end_pos": 23, "sequence_org": "S", "sequence_mut": "D", "comment": "No effect on DNA synthesis following DNA damage; when associated with D-29. No effect on cell-cycle progression, nor DNA synthesis in undamaged cells; when associated with D-8; D-29 and D-33. Impaired DNA double strand breaks repair; when associated with D-8; D-29 and D-33. Extended DNA damage-induced G2-M checkpoint; when associated with D-8; D-29 and D-33. Preferentially interacts with RAD51; when associated with D-8; D-29 and D-33.", "evidence": [ { "database": "UniProtKB", "id": "P15927", "url": "https://www.uniprot.org/uniprotkb/P15927" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" } ], "uniprot_canonical_ac": "P15927-1" }, { "start_pos": 29, "end_pos": 29, "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces phosphorylation by CDK1.", "evidence": [ { "database": "UniProtKB", "id": "P15927", "url": "https://www.uniprot.org/uniprotkb/P15927" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" }, { "database": "PubMed", "id": "9139719", "url": "https://pubmed.ncbi.nlm.nih.gov/9139719" } ], "uniprot_canonical_ac": "P15927-1" }, { "start_pos": 29, "end_pos": 29, "sequence_org": "S", "sequence_mut": "D", "comment": "No effect on DNA synthesis following DNA damage; when associated with D-23. No effect on cell-cycle progression, nor DNA synthesis in undamaged cells; when associated with D-8; D-23 and D-33. Impaired DNA double strand breaks repair; when associated with D-8; D-23 and D-33. Extended DNA damage-induced G2-M checkpoint; when associated with D-8; D-23 and D-33. Preferentially interacts with RAD51; when associated with D-8; D-23 and D-33.", "evidence": [ { "database": "UniProtKB", "id": "P15927", "url": "https://www.uniprot.org/uniprotkb/P15927" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" }, { "database": "PubMed", "id": "9139719", "url": "https://pubmed.ncbi.nlm.nih.gov/9139719" } ], "uniprot_canonical_ac": "P15927-1" }, { "start_pos": 33, "end_pos": 33, "sequence_org": "S", "sequence_mut": "D", "comment": "Lower homologous recombination efficiency following DNA double strand break. Impaired DNA synthesis following DNA damage; when associated with D-8. No effect on cell-cycle progression, nor DNA synthesis in undamaged cells; when associated with D-8; D-23 and D-29. Impaired DNA double strand breaks repair; when associated with D-8; D-23 and D-29. Extended DNA damage-induced G2-M checkpoint; when associated with D-8; D-23 and D-29. Preferentially interacts with RAD51; when associated with D-8; D-23 and D-29.", "evidence": [ { "database": "UniProtKB", "id": "P15927", "url": "https://www.uniprot.org/uniprotkb/P15927" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" } ], "uniprot_canonical_ac": "P15927-1" }, { "start_pos": 8, "end_pos": 8, "sequence_org": "S", "sequence_mut": "A", "comment": "Increased RAD51 foci formation and homologous recombination efficiency at DNA double-strand breaks; when associated with A-4.", "evidence": [ { "database": "UniProtKB", "id": "P15927", "url": "https://www.uniprot.org/uniprotkb/P15927" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" }, { "database": "PubMed", "id": "21731742", "url": "https://pubmed.ncbi.nlm.nih.gov/21731742" } ], "uniprot_canonical_ac": "P15927-1" }, { "start_pos": 8, "end_pos": 8, "sequence_org": "S", "sequence_mut": "D", "comment": "Lower homologous recombination efficiency following DNA double strand break. Impaired DNA synthesis following DNA damage; when associated with D-33. No effect on cell-cycle progression, nor DNA synthesis in undamaged cells; when associated with D-23; D-29 and D-33. Impaired DNA double strand breaks repair; when associated with D-23; D-29 and D-33. Extended DNA damage-induced G2-M checkpoint; when associated with D-23; D-29 and D-33. Preferentially interacts with RAD51; when associated with D-23; D-29 and D-33.", "evidence": [ { "database": "UniProtKB", "id": "P15927", "url": "https://www.uniprot.org/uniprotkb/P15927" }, { "database": "PubMed", "id": "20154705", "url": "https://pubmed.ncbi.nlm.nih.gov/20154705" }, { "database": "PubMed", "id": "21731742", "url": "https://pubmed.ncbi.nlm.nih.gov/21731742" } ], "uniprot_canonical_ac": "P15927-1" } ], "record_id": "pubmed.20154705", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 81 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, Unsal-Kacmaz K", "reference": { "type": "PubMed", "id": "20233725", "url": "https://pubmed.ncbi.nlm.nih.gov/20233725" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DNA end resection by CtIP and exonuclease 1 prevents genomic instability.", "journal": "EMBO reports", "date": "2010", "authors": "Eid W, Steger M, El-Shemerly M, Ferretti LP, Pena-Diaz J, Konig C, Valtorta E, Sartori AA, Ferrari S", "reference": { "type": "PubMed", "id": "21052091", "url": "https://pubmed.ncbi.nlm.nih.gov/21052091" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": 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helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21240188", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2011", "authors": "Ramirez-Lugo JS, Yoo HY, Yoon SJ, Dunphy WG", "reference": { "type": "PubMed", "id": "21263215", "url": "https://pubmed.ncbi.nlm.nih.gov/21263215" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21263215", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair.", "journal": "Genes & development", "date": "2011", "authors": "Nimonkar AV, Genschel J, Kinoshita E, Polaczek P, Campbell JL, Wyman C, Modrich P, Kowalczykowski SC", "reference": { "type": "PubMed", "id": "21325134", "url": "https://pubmed.ncbi.nlm.nih.gov/21325134" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", 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"https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21335604", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.", "journal": "Science (New York, N.Y.)", "date": "2011", "authors": "Cotta-Ramusino C, McDonald ER 3rd, Hurov K, Sowa ME, Harper JW, Elledge SJ", "reference": { "type": "PubMed", "id": "21659603", "url": "https://pubmed.ncbi.nlm.nih.gov/21659603" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS91-1", "protein_name": "E3 ubiquitin-protein ligase RAD18", "gene_name": "RAD18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ15-1", "protein_name": "SOSS complex subunit B1", "gene_name": "NABP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVH2-1", "protein_name": "Integrator complex subunit 7", "gene_name": "INTS7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15516-1", "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "CLOCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 55, "end_pos": 61, "sequence_org": "SWVSPDF", "sequence_mut": "AAAAAAA", "comment": "Inhibits binding to the 9-1-1 complex. 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1.", "journal": "Molecular biology of the cell", "date": "2011", "authors": "Meng Z, Capalbo L, Glover DM, Dunphy WG", "reference": { "type": "PubMed", "id": "21680713", "url": "https://pubmed.ncbi.nlm.nih.gov/21680713" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCP0-1", "protein_name": "Casein kinase I isoform gamma-1", "gene_name": "CSNK1G1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 169, "end_pos": 169, "sequence_org": "N", "sequence_mut": "A", "comment": "Loss of kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9HCP0", "url": "https://www.uniprot.org/uniprotkb/Q9HCP0" }, { "database": "PubMed", "id": "21680713", "url": "https://pubmed.ncbi.nlm.nih.gov/21680713" } ], "uniprot_canonical_ac": 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"sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ATR autophosphorylation as a molecular switch for checkpoint activation.", "journal": "Molecular cell", "date": "2011", "authors": "Liu S, Shiotani B, Lahiri M, Marechal A, Tse A, Leung CC, Glover JN, Yang XH, Zou L", "reference": { "type": "PubMed", "id": "21777809", "url": "https://pubmed.ncbi.nlm.nih.gov/21777809" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.", "journal": "Nucleic acids research", "date": "2012", "authors": "Sarkies P, Murat P, Phillips LG, Patel KJ, Balasubramanian S, Sale JE", "reference": { "type": "PubMed", "id": "22021381", "url": "https://pubmed.ncbi.nlm.nih.gov/22021381" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22021381", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction.", "journal": "Trends in genetics : TIG", "date": "2012", "authors": "Suhasini AN, Brosh RM Jr", "reference": { "type": "PubMed", "id": "22024395", "url": "https://pubmed.ncbi.nlm.nih.gov/22024395" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22024395", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2.", "journal": "Nature structural & molecular biology", "date": "2012", "authors": "Buis J, Stoneham T, Spehalski E, Ferguson DO", "reference": { "type": "PubMed", "id": "22231403", "url": "https://pubmed.ncbi.nlm.nih.gov/22231403" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22231403", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation of MDC1 is important for proper DNA damage response.", "journal": "The EMBO journal", "date": "2012", "authors": "Luo K, Zhang H, Wang L, Yuan J, Lou Z", "reference": { "type": "PubMed", "id": "22635276", "url": "https://pubmed.ncbi.nlm.nih.gov/22635276" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1840, "end_pos": 1840, "sequence_org": "K", "sequence_mut": "R", "comment": "Suppresses RNF4-mediated ubiquitination, accumulates at sites of DNA damage, defective homologous recombination.", "evidence": [ { "database": "UniProtKB", "id": "Q14676", "url": "https://www.uniprot.org/uniprotkb/Q14676" }, { "database": "PubMed", "id": "22635276", "url": "https://pubmed.ncbi.nlm.nih.gov/22635276" } ], "uniprot_canonical_ac": "Q14676-1" } ], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair.", "journal": "Genes & development", "date": "2012", "authors": "Galanty Y, Belotserkovskaya R, Coates J, Jackson SP", "reference": { "type": "PubMed", "id": "22661229", "url": "https://pubmed.ncbi.nlm.nih.gov/22661229" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, 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"tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": 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"protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22661229", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage.", "journal": "Genes & development", "date": "2012", "authors": "Yin Y, Seifert A, Chua JS, Maure JF, Golebiowski F, Hay RT", "reference": { "type": "PubMed", "id": "22661230", "url": "https://pubmed.ncbi.nlm.nih.gov/22661230" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22661230", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 142 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response.", "journal": "PLoS genetics", "date": "2012", "authors": "Xie J, Peng M, Guillemette S, Quan S, Maniatis S, Wu Y, Venkatesh A, Shaffer SA, Brosh RM Jr, Cantor SB", "reference": { "type": "PubMed", "id": "22792074", "url": "https://pubmed.ncbi.nlm.nih.gov/22792074" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22792074", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.", "journal": "Nucleic acids research", "date": "2012", "authors": "Liu S, Opiyo SO, Manthey K, Glanzer JG, Ashley AK, Amerin C, Troksa K, Shrivastav M, Nickoloff JA, Oakley GG", "reference": { "type": "PubMed", "id": "22977173", "url": "https://pubmed.ncbi.nlm.nih.gov/22977173" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2013-02-12", "authors": "Cho Won-Ho, Kang Young-Hoon, An Yun-Young, Tappin Inger, Hurwitz Jerard, Lee Joon-Kyu", "reference": { "type": "PubMed", "id": "23359676", "url": "https://pubmed.ncbi.nlm.nih.gov/23359676" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23359676", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.", "journal": "PLoS genetics", "date": "2013", "authors": "Wang H, Shi LZ, Wong CC, Han X, Hwang PY, Truong LN, Zhu Q, Shao Z, Chen DJ, Berns MW, Yates JR 3rd, Chen L, Wu X", "reference": { "type": "PubMed", "id": 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"gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25113031", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Sturzenegger A, Burdova K, Kanagaraj R, Levikova M, Pinto C, Cejka P, Janscak P", "reference": { "type": "PubMed", "id": "25122754", "url": "https://pubmed.ncbi.nlm.nih.gov/25122754" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone 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"uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "CtIP tetramer assembly is required for DNA-end resection and repair.", "journal": "Nature structural & molecular biology", "date": "2015", "authors": "Davies OR, Forment JV, Sun M, Belotserkovskaya R, Coates J, Galanty Y, Demir M, Morton CR, Rzechorzek NJ, Jackson SP, Pellegrini L", "reference": { "type": "PubMed", "id": "25558984", "url": "https://pubmed.ncbi.nlm.nih.gov/25558984" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cell Type-Specific Expression of Testis Elevated Genes Based on Transcriptomics and Antibody-Based Proteomics.", "journal": "J. Proteome Res.", "date": "2019", "authors": "Pineau Charles, Hikmet Feria, Zhang Cheng, Oksvold Per, Chen Shuqi, Fagerberg Linn, Uhl\u00e9n Mathias, Lindskog Cecilia", "reference": { "type": "PubMed", "id": "31429579", "url": "https://pubmed.ncbi.nlm.nih.gov/31429579" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAE3-1", "protein_name": "Calaxin", "gene_name": "CLXN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BS86-1", "protein_name": "Zona pellucida-binding protein 1", "gene_name": "ZPBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JQC9-1", "protein_name": "A-kinase anchor protein 4", "gene_name": "AKAP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TDG2-1", "protein_name": "Actin-related protein T1", "gene_name": "ACTRT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0A9-1", "protein_name": "Speriolin-like protein", "gene_name": "SPATC1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UL16-1", "protein_name": "Cilia- and flagella-associated protein 45", "gene_name": "CFAP45", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JX69-1", "protein_name": "Protein FAM209B", "gene_name": "FAM209B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYS4-1", "protein_name": "Dynein axonemal assembly factor 8", "gene_name": "DNAAF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXZ1-1", "protein_name": "Sarcoma antigen 1", "gene_name": "SAGE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SZB4-1", "protein_name": "Uncharacterized protein C9orf50", "gene_name": "C9orf50", "tax_name": "Human" }, { "uniprot_canonical_ac": "B2RC85-1", "protein_name": "Radial spoke head 10 homolog B2", "gene_name": "RSPH10B2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C881-1", "protein_name": "Radial spoke head 10 homolog B", "gene_name": "RSPH10B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDZ0-1", "protein_name": "BEN domain-containing protein 2", "gene_name": "BEND2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZ16-1", "protein_name": "Sperm acrosome developmental regulator", "gene_name": "SPACDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60732-1", "protein_name": "Melanoma-associated antigen C1", "gene_name": "MAGEC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P3R8-1", "protein_name": "Serine/threonine-protein kinase Nek5", "gene_name": "NEK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHX4-1", "protein_name": "Spermatogenesis-associated protein 3", "gene_name": "SPATA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMU9-1", "protein_name": "Cancer/testis antigen family 45 member A10", "gene_name": "CT45A10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMU8-1", "protein_name": "Cancer/testis antigen family 45 member A5", "gene_name": "CT45A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PV4-1", "protein_name": "Paraneoplastic antigen-like protein 5", "gene_name": "PNMA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FBB7-1", "protein_name": "Shugoshin 1", "gene_name": "SGO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WR6-1", "protein_name": "CHD1 helical C-terminal domain containing protein 1", "gene_name": "CHCT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L0X2-1", "protein_name": "Glutamate-rich protein 6", "gene_name": "ERICH6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13117-1", "protein_name": "Deleted in azoospermia protein 2", "gene_name": "DAZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHU0-1", "protein_name": "Cancer/testis antigen family 45 member A3", "gene_name": "CT45A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48380-1", "protein_name": "Transcription factor RFX3", "gene_name": "RFX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "B1AJZ9-1", "protein_name": "Forkhead-associated domain-containing protein 1", "gene_name": "FHAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9W6-1", "protein_name": "Protein boule-like", "gene_name": "BOLL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75330-1", "protein_name": "Hyaluronan mediated motility receptor", "gene_name": "HMMR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78358-1", "protein_name": "Cancer/testis antigen 1", "gene_name": "CTAG1A; CTAG1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T1B0-1", "protein_name": "Axonemal dynein light chain domain-containing protein 1", "gene_name": "AXDND1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR90-1", "protein_name": "Deleted in azoospermia protein 3", "gene_name": "DAZ3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G0P3-1", "protein_name": "Axonemal central pair apparatus protein HYDIN", "gene_name": "HYDIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WS3-1", "protein_name": "Oocyte-secreted protein 2", "gene_name": "OOSP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NTG1-1", "protein_name": "Polycystin family receptor for egg jelly", "gene_name": "PKDREJ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBF8-1", "protein_name": "Protein FAM81A", "gene_name": "FAM81A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5TEA6-1", "protein_name": "Protein sel-1 homolog 2", "gene_name": "SEL1L2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14565-1", "protein_name": "Meiotic recombination protein DMC1 homolog", "gene_name": "DMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96M34-1", "protein_name": "Testis-specific expressed protein 55", "gene_name": "TEX55", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5N4-1", "protein_name": "Uncharacterized protein C3orf22", "gene_name": "C3orf22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5U0-1", "protein_name": "Uncharacterized protein C11orf42", "gene_name": "C11orf42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3SXM0-1", "protein_name": "DDB1- and CUL4-associated factor 4-like protein 1", "gene_name": "DCAF4L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SG3-1", "protein_name": "Deleted in azoospermia protein 4", "gene_name": "DAZ4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92904-1", "protein_name": "Deleted in azoospermia-like", "gene_name": "DAZL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQZ3-1", "protein_name": "Deleted in azoospermia protein 1", "gene_name": "DAZ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53EV4-1", "protein_name": "Leucine-rich repeat-containing protein 23", "gene_name": "LRRC23", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NLX4-1", "protein_name": "Transmembrane protein 210", "gene_name": "TMEM210", "tax_name": "Human" } ], 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Germline polymorphisms in genes maintaining the replication fork predict the efficacy of oxaliplatin and irinotecan in patients with metastatic colorectal cancer.", "journal": "British journal of cancer", "date": "2022", "authors": "Arai H, Xiao Y, Millstein J, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Parikh AR, Lenz HJ", "reference": { "type": "PubMed", "id": "34689170", "url": "https://pubmed.ncbi.nlm.nih.gov/34689170" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure of a human replisome shows the organisation and interactions of a DNA replication machine.", "journal": "EMBO J.", "date": "2021", "authors": "Jones Morgan L, Baris Yasemin, Taylor Martin R G, Yeeles Joseph T P", "reference": { "type": "PubMed", "id": "34694004", "url": "https://pubmed.ncbi.nlm.nih.gov/34694004" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56282-1", "protein_name": "DNA polymerase epsilon subunit 2", "gene_name": "POLE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRT9-1", "protein_name": "DNA replication complex GINS protein SLD5", "gene_name": "GINS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07864-1", "protein_name": "DNA polymerase epsilon catalytic subunit A", "gene_name": "POLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y248-1", "protein_name": "DNA replication complex GINS protein PSF2", "gene_name": "GINS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75717-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "WDHD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25205-1", "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33992-1", "protein_name": "DNA replication licensing factor MCM5", "gene_name": "MCM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14691-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "GINS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRX5-1", "protein_name": "DNA replication complex GINS protein PSF3", "gene_name": "GINS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33991-1", "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34694004", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A conserved mechanism for regulating replisome disassembly in eukaryotes.", "journal": "Nature", "date": "2021", "authors": "Jenkyn-Bedford Michael, Jones Morgan L, Baris Yasemin, Labib Karim P M, Cannone Giuseppe, Yeeles Joseph T P, Deegan Tom D", "reference": { "type": "PubMed", "id": "34700328", "url": "https://pubmed.ncbi.nlm.nih.gov/34700328" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56282-1", "protein_name": "DNA polymerase epsilon subunit 2", "gene_name": "POLE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRT9-1", "protein_name": "DNA replication complex GINS protein SLD5", "gene_name": "GINS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15369-1", "protein_name": "Elongin-C", "gene_name": "ELOC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07864-1", "protein_name": "DNA polymerase epsilon catalytic subunit A", "gene_name": "POLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L50-1", "protein_name": "Leucine-rich repeat protein 1", "gene_name": "LRR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15370-1", "protein_name": "Elongin-B", "gene_name": "ELOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y248-1", "protein_name": "DNA replication complex GINS protein PSF2", "gene_name": "GINS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75717-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "WDHD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62877-1", "protein_name": "E3 ubiquitin-protein ligase RBX1", "gene_name": "RBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13617-1", "protein_name": "Cullin-2", "gene_name": "CUL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25205-1", "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33992-1", "protein_name": "DNA replication licensing factor MCM5", "gene_name": "MCM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14691-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "GINS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRX5-1", "protein_name": "DNA replication complex GINS protein PSF3", "gene_name": "GINS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33991-1", "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34700328", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fast and efficient DNA replication with purified human proteins.", "journal": "Nature", "date": "2022-06", "authors": "Baris Yasemin, Taylor Martin R G, Aria Valentina, Yeeles Joseph T P", "reference": { "type": "PubMed", "id": "35585232", "url": "https://pubmed.ncbi.nlm.nih.gov/35585232" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14566-1", "protein_name": "DNA replication licensing factor MCM6", "gene_name": "MCM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRT9-1", "protein_name": "DNA replication complex GINS protein SLD5", "gene_name": "GINS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y248-1", "protein_name": "DNA replication complex GINS protein PSF2", "gene_name": "GINS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75419-1", "protein_name": "Cell division control protein 45 homolog", "gene_name": "CDC45", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75717-1", "protein_name": "WD repeat and HMG-box DNA-binding protein 1", "gene_name": "WDHD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49736-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "MCM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12004-1", "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25205-1", "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33992-1", "protein_name": "DNA replication licensing factor MCM5", "gene_name": "MCM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14691-1", "protein_name": "DNA replication complex GINS protein PSF1", "gene_name": "GINS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRX5-1", "protein_name": "DNA replication complex GINS protein PSF3", "gene_name": "GINS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33991-1", "protein_name": "DNA replication licensing factor MCM4", "gene_name": "MCM4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.35585232", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The mechanism of radiotherapy for lung adenocarcinoma in promoting protein SIRT6-mediated deacetylation of RBBP8 to enhance the sensitivity of targeted therapy.", "journal": "International journal of immunopathology and pharmacology", "date": "2022", "authors": "Wang J, Sheng Z, Dong Z, Wu Q, Cai Y", "reference": { "type": "PubMed", "id": "36172813", "url": "https://pubmed.ncbi.nlm.nih.gov/36172813" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92547-1", "protein_name": "DNA topoisomerase 2-binding protein 1", "gene_name": "TOPBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E14-1", "protein_name": "RecQ-mediated genome instability protein 2", "gene_name": "RMI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75943-1", "protein_name": "Cell cycle checkpoint protein RAD17", "gene_name": "RAD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSD3-1", "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY27-1", "protein_name": "Serine/threonine-protein phosphatase 4 regulatory subunit 2", "gene_name": "PPP4R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35249-1", "protein_name": "Replication factor C subunit 4", "gene_name": "RFC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13472-1", "protein_name": "DNA topoisomerase 3-alpha", "gene_name": "TOP3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51530-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "DNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE1-1", "protein_name": "ATR-interacting protein", "gene_name": "ATRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13535-1", "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9A7-1", "protein_name": "RecQ-mediated genome instability protein 1", "gene_name": "RMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35250-1", "protein_name": "Replication factor C subunit 2", "gene_name": "RFC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14757-1", "protein_name": "Serine/threonine-protein kinase Chk1", "gene_name": "CHEK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60510-1", "protein_name": "Serine/threonine-protein phosphatase 4 catalytic subunit", "gene_name": "PPP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40938-1", "protein_name": "Replication factor C subunit 3", "gene_name": "RFC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ84-1", "protein_name": "Exonuclease 1", "gene_name": "EXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BX63-1", "protein_name": "Fanconi anemia group J protein", "gene_name": "BRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40937-1", "protein_name": "Replication factor C subunit 5", "gene_name": "RFC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T7-1", "protein_name": "NAD-dependent protein deacylase sirtuin-6", "gene_name": "SIRT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6WBX8-5", "protein_name": "Cell cycle checkpoint control protein RAD9B", "gene_name": "RAD9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW4-1", "protein_name": "Claspin", "gene_name": "CLSPN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS1-1", "protein_name": "Protein timeless homolog", "gene_name": "TIMELESS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60921-1", "protein_name": "Checkpoint protein HUS1", "gene_name": "HUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60671-1", "protein_name": "Cell cycle checkpoint protein RAD1", "gene_name": "RAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99638-1", "protein_name": "Cell cycle checkpoint control protein RAD9A", "gene_name": "RAD9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVW5", "url": "https://www.uniprot.org/uniprotkb/Q9BVW5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36172813", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "OGA mutant aberrantly hydrolyzes O-GlcNAc modification from PDLIM7 to modulate p53 and cytoskeleton in promoting cancer cell malignancy.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2024-06-11", "authors": "Hu Chia-Wei, Wang Ao, Fan Dacheng, Worth Matthew, Chen Zhengwei, Huang Junfeng, Xie Jinshan, Macdonald John, Li Lingjun, Jiang Jiaoyang", "reference": { "type": "PubMed", "id": "38838015", "url": "https://pubmed.ncbi.nlm.nih.gov/38838015" }, "referenced_glycans": [ { "glytoucan_ac": "G49108TO" } ], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVW5-1", "protein_name": "TIMELESS-interacting protein", "gene_name": "TIPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2N5-1", "protein_name": "RNA-binding protein 27", "gene_name": "RBM27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15572-1", "protein_name": "TATA box-binding protein-associated factor RNA polymerase I subunit C", "gene_name": "TAF1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14684-1", "protein_name": "Ribosomal RNA processing protein 1 homolog B", "gene_name": "RRP1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2L5-1", "protein_name": "Trafficking protein particle complex subunit 8", "gene_name": "TRAPPC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z739-1", "protein_name": "YTH domain-containing family protein 3", "gene_name": "YTHDF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6V9R5-1", "protein_name": "Zinc finger protein 562", "gene_name": "ZNF562", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N7Q3-1", "protein_name": "Zinc finger protein 676", "gene_name": "ZNF676", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULM3-1", "protein_name": "YEATS domain-containing protein 2", "gene_name": "YEATS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15652-1", "protein_name": "Jumonji domain-containing protein 1C", "gene_name": "JMJD1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ03-1", "protein_name": "Coronin-2B", "gene_name": "CORO2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09666-1", "protein_name": "Neuroblast differentiation-associated protein AHNAK", "gene_name": "AHNAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3H0-2", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "ANKRD33", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16186-1", "protein_name": "Proteasomal ubiquitin receptor ADRM1", "gene_name": "ADRM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27540-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator", "gene_name": "ARNT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16512-1", "protein_name": "Serine/threonine-protein kinase N1", "gene_name": "PKN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15750-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1", "gene_name": "TAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IWH7-1", "protein_name": "Anoctamin-7", "gene_name": "ANO7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51610-1", "protein_name": "Host cell factor 1", "gene_name": "HCFC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVW6-1", "protein_name": "AT-rich interactive domain-containing protein 3B", "gene_name": "ARID3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18846-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-1", "gene_name": "ATF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWZ3-1", "protein_name": "Ankyrin repeat and KH domain-containing protein 1", "gene_name": "ANKHD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCK8-1", "protein_name": "ATP-dependent chromatin remodeler CHD8", "gene_name": "CHD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95817-1", "protein_name": "BAG family molecular chaperone regulator 3", "gene_name": "BAG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P4R8-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "NFRKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHY1-1", "protein_name": "Nuclear receptor-binding protein", "gene_name": "NRBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YP4-1", "protein_name": "Transcriptional repressor p66-alpha", "gene_name": "GATAD2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4A3-1", "protein_name": "Serine/threonine-protein kinase WNK1", "gene_name": "WNK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05387-1", "protein_name": "Large ribosomal subunit protein P2", "gene_name": "RPLP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14008-1", "protein_name": "Cytoskeleton-associated protein 5", "gene_name": "CKAP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30622-3", "protein_name": "CAP-Gly domain-containing linker protein 1", "gene_name": "CLIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P85037-1", "protein_name": "Forkhead box protein K1", "gene_name": "FOXK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3X1-1", "protein_name": "Formin-binding protein 4", "gene_name": "FNBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z417-1", "protein_name": "FMR1-interacting protein NUFIP2", "gene_name": "NUFIP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPN6-1", "protein_name": "SR-related and CTD-associated factor 8", "gene_name": "SCAF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93052-1", "protein_name": "Lipoma-preferred partner", "gene_name": "LPP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6MZP7-1", "protein_name": "Protein lin-54 homolog", "gene_name": "LIN54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48431-1", "protein_name": "Transcription factor SOX-2", "gene_name": "SOX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PK6-1", "protein_name": "RNA-binding protein 14", "gene_name": "RBM14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15437-1", "protein_name": "Protein transport protein Sec23B", "gene_name": "SEC23B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57058-1", "protein_name": "Hormonally up-regulated neu tumor-associated kinase", "gene_name": "HUNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94913-1", "protein_name": "Pre-mRNA cleavage complex 2 protein Pcf11", "gene_name": "PCF11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WW12-1", "protein_name": "PEST proteolytic signal-containing nuclear protein", "gene_name": "PCNP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49454-1", "protein_name": "Centromere protein F", "gene_name": "CENPF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10253-1", "protein_name": "Lysosomal alpha-glucosidase", "gene_name": "GAA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14149-1", "protein_name": "MORC family CW-type zinc finger protein 3", "gene_name": "MORC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNB6-1", "protein_name": "NF-X1-type zinc finger protein NFXL1", "gene_name": "NFXL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14859-1", "protein_name": "POU domain, class 2, transcription factor 1", "gene_name": "POU2F1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92540-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG7", "gene_name": "SMG7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q495C1-1", "protein_name": "Probable E3 SUMO-protein ligase RNF212", "gene_name": "RNF212", "tax_name": "Human" }, { "uniprot_canonical_ac": "A3KN83-1", "protein_name": "Protein strawberry notch homolog 1", "gene_name": "SBNO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95487-1", "protein_name": "Protein transport protein Sec24B", "gene_name": "SEC24B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZRS2-1", "protein_name": "Chromatin remodeling protein SRCAP", "gene_name": "SRCAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04726-1", "protein_name": "Transducin-like enhancer protein 3", "gene_name": "TLE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ35-1", "protein_name": "Serine/arginine repetitive matrix protein 2", "gene_name": "SRRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P227-1", "protein_name": "Rho GTPase-activating protein 23", "gene_name": "ARHGAP23", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18583-1", "protein_name": "Protein SON", "gene_name": "SON", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43278-1", "protein_name": "Kunitz-type protease inhibitor 1", "gene_name": "SPINT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00839-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein U", "gene_name": "HNRNPU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DF8-1", "protein_name": "Splicing factor ESS-2 homolog", "gene_name": "ESS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JWR5-1", "protein_name": "Protein DOP1A", "gene_name": "DOP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTC0-4", "protein_name": "Death-inducer obliterator 1", "gene_name": "DIDO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P265-1", "protein_name": "Disco-interacting protein 2 homolog B", "gene_name": "DIP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01082-1", "protein_name": "Spectrin beta chain, non-erythrocytic 1", "gene_name": "SPTBN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPF5-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "DMAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3E5-1", "protein_name": "LisH domain-containing protein ARMC9", "gene_name": "ARMC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99700-1", "protein_name": "Ataxin-2", "gene_name": "ATXN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWM7-1", "protein_name": "Ataxin-2-like protein", "gene_name": "ATXN2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFW9-1", "protein_name": "Rab effector MyRIP", "gene_name": "MYRIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAU0-1", "protein_name": "Pleckstrin homology domain-containing family A member 5", "gene_name": "PLEKHA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z589-1", "protein_name": "BRCA2-interacting transcriptional repressor EMSY", "gene_name": "EMSY", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y467-1", "protein_name": "Sal-like protein 2", "gene_name": "SALL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHR5-1", "protein_name": "SAP30-binding protein", "gene_name": "SAP30BP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01955-1", "protein_name": "Collagen alpha-3(IV) chain", "gene_name": "COL4A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UVJ0-1", "protein_name": "Spindle assembly abnormal protein 6 homolog", "gene_name": "SASS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWZ8-1", "protein_name": "SURP and G-patch domain-containing protein 1", "gene_name": "SUGP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07942-1", "protein_name": "Laminin subunit beta-1", "gene_name": "LAMB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86U70-1", "protein_name": "LIM domain-binding protein 1", "gene_name": "LDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZM5-1", "protein_name": "Protein YIPF3", "gene_name": "YIPF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92615-1", "protein_name": "La-related protein 4B", "gene_name": "LARP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LBC6-1", "protein_name": "Lysine-specific demethylase 3B", "gene_name": "KDM3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2X0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "gene_name": "MED16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHV7-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 13", "gene_name": "MED13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14814-1", "protein_name": "Myocyte-specific enhancer factor 2D", "gene_name": "MEF2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60502-1", "protein_name": "Protein O-GlcNAcase", "gene_name": "OGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96Q89-1", "protein_name": "Kinesin-like protein KIF20B", "gene_name": "KIF20B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZ21-1", "protein_name": "Phosphatase and actin regulator 4", "gene_name": "PHACTR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCD5-1", "protein_name": "Nuclear receptor coactivator 5", "gene_name": "NCOA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y520-1", "protein_name": "Protein PRRC2C", "gene_name": "PRRC2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KR1-1", "protein_name": "Zinc finger RNA-binding protein", "gene_name": "ZFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49848-1", "protein_name": "Transcription initiation factor TFIID subunit 6", "gene_name": "TAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00268-1", "protein_name": "Transcription initiation factor TFIID subunit 4", "gene_name": "TAF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN79-1", "protein_name": "Transcription factor SOX-13", "gene_name": "SOX13", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15880-1", "protein_name": "Small ribosomal subunit protein uS5", "gene_name": "RPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43432-1", "protein_name": "Eukaryotic translation initiation factor 4 gamma 3", "gene_name": "EIF4G3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31153-1", "protein_name": "S-adenosylmethionine synthase isoform type-2", "gene_name": "MAT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27816-1", "protein_name": "Microtubule-associated protein 4", "gene_name": "MAP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWR8-1", "protein_name": "Sialidase-4", "gene_name": "NEU4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKM7-1", "protein_name": "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase", "gene_name": "MAN1B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWI9-4", "protein_name": "MAX gene-associated protein", "gene_name": "MGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15723-5", "protein_name": "ETS-related transcription factor Elf-2", "gene_name": "ELF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5A7-1", "protein_name": "NEDD8 ultimate buster 1", "gene_name": "NUB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P50-3", "protein_name": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3", "gene_name": "ACAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": "Ubiquilin-2", "gene_name": "UBQLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27824-1", "protein_name": "Calnexin", "gene_name": "CANX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15067-1", "protein_name": "Peroxisomal acyl-coenzyme A oxidase 1", "gene_name": "ACOX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40222-1", "protein_name": "Alpha-taxilin", "gene_name": "TXLNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75179-1", "protein_name": "Ankyrin repeat domain-containing protein 17", "gene_name": "ANKRD17", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75923-1", "protein_name": "Dysferlin", "gene_name": "DYSF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y217-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "MTMR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2J4-1", "protein_name": "Angiomotin-like protein 2", "gene_name": "AMOTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDV7-1", "protein_name": "Trinucleotide repeat-containing gene 6A protein", "gene_name": "TNRC6A", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5YKK6-1", "protein_name": "CCR4-NOT transcription complex subunit 1", "gene_name": "CNOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14677-1", "protein_name": "Clathrin interactor 1", "gene_name": "CLINT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XX4-1", "protein_name": "Extracellular matrix organizing protein FRAS1", "gene_name": "FRAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3K3-1", "protein_name": "Pogo transposable element with ZNF domain", "gene_name": "POGZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94842-1", "protein_name": "TOX high mobility group box family member 4", "gene_name": "TOX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53ET0-1", "protein_name": "CREB-regulated transcription coactivator 2", "gene_name": "CRTC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL6-1", "protein_name": "Copine-7", "gene_name": "CPNE7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYJ8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "gene_name": "TAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12830-1", "protein_name": "Nucleosome-remodeling factor subunit BPTF", "gene_name": "BPTF", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60885-1", "protein_name": "Bromodomain-containing protein 4", "gene_name": "BRD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0E9-1", "protein_name": "Bromodomain-containing protein 8", "gene_name": "BRD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43852-1", "protein_name": "Calumenin", "gene_name": "CALU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13620-2", "protein_name": "Cullin-4B", "gene_name": "CUL4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12948-1", "protein_name": "Forkhead box protein C1", "gene_name": "FOXC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04637-1", "protein_name": "Eukaryotic translation initiation factor 4 gamma 1", "gene_name": "EIF4G1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JSZ5-1", "protein_name": "Protein PRRC2B", "gene_name": "PRRC2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T58-1", "protein_name": "Msx2-interacting protein", "gene_name": "SPEN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53992-1", "protein_name": "Protein transport protein Sec24C", "gene_name": "SEC24C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46013-1", "protein_name": "Proliferation marker protein Ki-67", "gene_name": "MKI67", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13310-1", "protein_name": "Polyadenylate-binding protein 4", "gene_name": "PABPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14671-1", "protein_name": "Pumilio homolog 1", "gene_name": "PUM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBS9-1", "protein_name": "Thioredoxin domain-containing protein 5", "gene_name": "TXNDC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULT8-1", "protein_name": "E3 ubiquitin-protein ligase HECTD1", "gene_name": "HECTD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRJ2-1", "protein_name": "Putative uncharacterized protein GSN-AS1", "gene_name": "GSN-AS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2KHR3-1", "protein_name": "Glutamine and serine-rich protein 1", "gene_name": "QSER1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z6J0-1", "protein_name": "E3 ubiquitin-protein ligase SH3RF1", "gene_name": "SH3RF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3B3-1", "protein_name": "Transmembrane emp24 domain-containing protein 7", "gene_name": "TMED7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B49-1", "protein_name": "Mitochondrial import receptor subunit TOM6 homolog", "gene_name": "TOMM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T6F2-1", "protein_name": "Ubiquitin-associated protein 2", "gene_name": "UBAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14157-2", "protein_name": "Ubiquitin-associated protein 2-like", "gene_name": "UBAP2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYJ9-1", "protein_name": "YTH domain-containing family protein 1", "gene_name": "YTHDF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKD1-1", "protein_name": "Glucocorticoid modulatory element-binding protein 2", "gene_name": "GMEB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12962-1", "protein_name": "Transcription initiation factor TFIID subunit 10", "gene_name": "TAF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKY1-1", "protein_name": "Zinc fingers and homeoboxes protein 1", "gene_name": "ZHX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49336-1", "protein_name": "Cyclin-dependent kinase 8", "gene_name": "CDK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05388-1", "protein_name": "Large ribosomal subunit protein uL10", "gene_name": "RPLP0", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HC4-1", "protein_name": "PDZ and LIM domain protein 5", "gene_name": "PDLIM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXV6-1", "protein_name": "CDKN2A-interacting protein", "gene_name": "CDKN2AIP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N8S7-1", "protein_name": "Protein enabled homolog", "gene_name": "ENAH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95486-1", "protein_name": "Protein transport protein Sec24A", "gene_name": "SEC24A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15942-1", "protein_name": "Zyxin", "gene_name": "ZYX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14314-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PRKCSH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2V2M9-1", "protein_name": "FH1/FH2 domain-containing protein 3", "gene_name": "FHOD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UN15-1", "protein_name": "Pre-mRNA 3'-end-processing factor FIP1", "gene_name": "FIP1L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20719-1", "protein_name": "Homeobox protein Hox-A5", "gene_name": "HOXA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42694-1", "protein_name": "ATP-dependent RNA helicase with zinc finger domain", "gene_name": "HELZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20810-1", "protein_name": "Calpastatin", "gene_name": "CAST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z5L9-1", "protein_name": "Interferon regulatory factor 2-binding protein 2", "gene_name": "IRF2BP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IU81-1", "protein_name": "Interferon regulatory factor 2-binding protein 1", "gene_name": "IRF2BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXG6-1", "protein_name": "MAP kinase-activating death domain protein", "gene_name": "MADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULH7-1", "protein_name": "Myocardin-related transcription factor B", "gene_name": "MRTFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UGV2-1", "protein_name": "Protein NDRG3", "gene_name": "NDRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR12-1", "protein_name": "PDZ and LIM domain protein 7", "gene_name": "PDLIM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L91-1", "protein_name": "E1A-binding protein p400", "gene_name": "EP400", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZ81-1", "protein_name": "ELMO domain-containing protein 2", "gene_name": "ELMOD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04727-1", "protein_name": "Transducin-like enhancer protein 4", "gene_name": "TLE4", "tax_name": "Human" }, { "uniprot_canonical_ac": "B4DXR9-1", "protein_name": "Zinc finger protein 732", "gene_name": "ZNF732", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXI9-1", "protein_name": "Transcriptional repressor p66-beta", "gene_name": "GATAD2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75928-1", "protein_name": "E3 SUMO-protein ligase PIAS2", "gene_name": "PIAS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8Y8-1", "protein_name": "Golgi reassembly-stacking protein 2", "gene_name": "GORASP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00505-1", "protein_name": "Aspartate aminotransferase, mitochondrial", 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Biol. Chem.", "date": "2001", "authors": "Kurihara N, Menaa C, Maeda H, Haile DJ, Reddy SV", "reference": { "type": "PubMed", "id": "11551898", "url": "https://pubmed.ncbi.nlm.nih.gov/11551898" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q92882-1", "protein_name": "Osteoclast-stimulating factor 1", "gene_name": "OSTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16637-1", "protein_name": "Survival motor neuron protein", "gene_name": "SMN1; SMN2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q92882", "url": "https://www.uniprot.org/uniprotkb/Q92882" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11551898", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": 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complex", "gene_name": "NBAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8G2-1", "protein_name": "Caspase activity and apoptosis inhibitor 1", "gene_name": "CAAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95747-1", "protein_name": "Serine/threonine-protein kinase OSR1", "gene_name": "OXSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75643-1", "protein_name": "U5 small nuclear ribonucleoprotein 200 kDa helicase", "gene_name": "SNRNP200", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08945-1", "protein_name": "FACT complex subunit SSRP1", "gene_name": "SSRP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05114-1", "protein_name": "Non-histone chromosomal protein HMG-14", "gene_name": "HMGN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99733-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "NAP1L4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1E3-1", "protein_name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "gene_name": "NUCKS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZT2-1", "protein_name": "Opioid growth factor receptor", "gene_name": "OGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5B6-1", "protein_name": "PAX3- and PAX7-binding protein 1", "gene_name": "PAXBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92626-1", "protein_name": "Peroxidasin homolog", "gene_name": "PXDN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00264-1", "protein_name": "Membrane-associated progesterone receptor component 1", "gene_name": "PGRMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q63HN8-3", "protein_name": "E3 ubiquitin-protein ligase RNF213", "gene_name": "RNF213", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00193-1", "protein_name": "Small acidic protein", "gene_name": "C11orf58; SMAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVC0-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24534-1", "protein_name": "Elongation factor 1-beta", "gene_name": "EEF1B2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UH62-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "ARMCX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95671-1", "protein_name": "Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein", "gene_name": "ASMTL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13283-1", "protein_name": "Ras GTPase-activating protein-binding protein 1", "gene_name": "G3BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96G23-1", "protein_name": "Ceramide synthase 2", "gene_name": "CERS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29692-1", "protein_name": "Elongation factor 1-delta", "gene_name": "EEF1D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40199-1", "protein_name": "Cell adhesion molecule CEACAM6", "gene_name": "CEACAM6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95674-1", "protein_name": "Phosphatidate cytidylyltransferase 2", "gene_name": "CDS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95400-1", "protein_name": "CD2 antigen cytoplasmic tail-binding protein 2", "gene_name": "CD2BP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35659-1", "protein_name": "Protein DEK", "gene_name": "DEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12996-1", "protein_name": "Cleavage stimulation factor subunit 3", "gene_name": "CSTF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35579-1", "protein_name": "Myosin-9", "gene_name": "MYH9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13576-1", "protein_name": "Ras GTPase-activating-like protein IQGAP2", "gene_name": "IQGAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UDY2-1", "protein_name": "Tight junction protein 2", "gene_name": "TJP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95239-1", "protein_name": "Chromosome-associated kinesin KIF4A", "gene_name": "KIF4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2W1-1", "protein_name": "Thyroid hormone receptor-associated protein 3", "gene_name": "THRAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15435-1", "protein_name": "Protein phosphatase 1 regulatory subunit 7", "gene_name": "PPP1R7", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"Programmed cell death protein 5", "gene_name": "PDCD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZN4-1", "protein_name": "EH domain-containing protein 2", "gene_name": "EHD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94929-1", "protein_name": "Actin-binding LIM protein 3", "gene_name": "ABLIM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13861-1", "protein_name": "cAMP-dependent protein kinase type II-alpha regulatory subunit", "gene_name": "PRKAR2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08238-1", "protein_name": "Heat shock protein HSP 90-beta", "gene_name": "HSP90AB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07910-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins C1/C2", "gene_name": "HNRNPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T8D3-1", "protein_name": "Acyl-CoA-binding domain-containing protein 5", "gene_name": "ACBD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKV3-1", "protein_name": "Apoptotic chromatin condensation inducer in the nucleus", "gene_name": "ACIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13185-1", "protein_name": "Chromobox protein homolog 3", "gene_name": "CBX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P83916-1", "protein_name": "Chromobox protein homolog 1", "gene_name": "CBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27824-1", "protein_name": "Calnexin", "gene_name": "CANX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54105-1", "protein_name": "Methylosome subunit pICln", "gene_name": "CLNS1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35221-1", "protein_name": "Catenin alpha-1", "gene_name": "CTNNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NE71-1", "protein_name": "ATP-binding cassette sub-family F member 1", "gene_name": "ABCF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60763-1", "protein_name": "General vesicular transport factor p115", "gene_name": "USO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55081-1", "protein_name": "Microfibrillar-associated protein 1", "gene_name": "MFAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02768-1", "protein_name": "Albumin", "gene_name": "ALB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10644-1", "protein_name": "cAMP-dependent protein kinase type I-alpha regulatory subunit", "gene_name": "PRKAR1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31323-1", "protein_name": "cAMP-dependent protein kinase type II-beta regulatory subunit", "gene_name": "PRKAR2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13895-1", "protein_name": "Bystin", "gene_name": "BYSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25788-1", "protein_name": "Proteasome subunit alpha type-3", "gene_name": "PSMA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JRA6-1", "protein_name": "Transport and Golgi organization protein 1 homolog", "gene_name": "MIA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UI47-1", "protein_name": "Catenin alpha-3", "gene_name": "CTNNA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75475-1", "protein_name": "PC4 and SFRS1-interacting protein", "gene_name": "PSIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14677-1", "protein_name": "Clathrin interactor 1", "gene_name": "CLINT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVM1-1", "protein_name": "Protein eva-1 homolog B", "gene_name": "EVA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14694-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10", "gene_name": "USP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22059-1", "protein_name": "Oxysterol-binding protein 1", "gene_name": "OSBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06210-1", "protein_name": "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "gene_name": "GFPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5J1-1", "protein_name": "U3 small nucleolar RNA-associated protein 18 homolog", "gene_name": "UTP18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13557-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYF8-1", "protein_name": "Bcl-2-associated transcription factor 1", "gene_name": "BCLAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7L9-1", "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3", "gene_name": "SUDS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L1Q6-1", "protein_name": "eIF5-mimic protein 2", "gene_name": "BZW1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14137-1", "protein_name": "Ribosome biogenesis protein BOP1", "gene_name": "BOP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0D6-1", "protein_name": "5'-3' exoribonuclease 2", "gene_name": "XRN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR7-1", "protein_name": "ATP-dependent RNA helicase DDX24", "gene_name": "DDX24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13435-1", "protein_name": "Splicing factor 3B subunit 2", "gene_name": "SF3B2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08495-1", "protein_name": "Dematin", "gene_name": "DMTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JSZ5-1", "protein_name": "Protein PRRC2B", "gene_name": "PRRC2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02794-1", "protein_name": "Ferritin heavy chain", "gene_name": "FTH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60231-1", "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "gene_name": "DHX16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99549-1", "protein_name": "M-phase phosphoprotein 8", "gene_name": "MPHOSPH8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15459-1", "protein_name": "Splicing factor 3A subunit 1", "gene_name": "SF3A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35580-1", "protein_name": "Myosin-10", "gene_name": "MYH10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15746-1", "protein_name": "Myosin light chain kinase, smooth muscle", "gene_name": "MYLK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13442-1", "protein_name": "28 kDa heat- and acid-stable phosphoprotein", "gene_name": "PDAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15019-1", "protein_name": 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"gene_name": "NOP14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96I25-1", "protein_name": "Splicing factor 45", "gene_name": "RBM17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G0J3-1", "protein_name": "La-related protein 7", "gene_name": "LARP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UN15-1", "protein_name": "Pre-mRNA 3'-end-processing factor FIP1", "gene_name": "FIP1L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14568-1", "protein_name": "Heat shock protein HSP 90-alpha A2", "gene_name": "HSP90AA2P", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q27J81-1", "protein_name": "Inverted formin-2", "gene_name": "INF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17096-1", "protein_name": "High mobility group protein HMG-I/HMG-Y", "gene_name": "HMGA1", "tax_name": "Human" }, { 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"Oligosaccharyltransferase is highly specific for the hydroxy amino acid in Asn-Xaa-Thr/Ser.", "journal": "FEBS letters", "date": "2001", "authors": "Breuer W, Klein RA, Hardt B, Bartoschek A, Bause E", "reference": { "type": "PubMed", "id": "11470266", "url": "https://pubmed.ncbi.nlm.nih.gov/11470266" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "gene_name": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Saxena A, Yik JH, Weigel PH", "reference": { "type": "PubMed", "id": "12089159", "url": "https://pubmed.ncbi.nlm.nih.gov/12089159" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- 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"UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12089159", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Nonpalmitoylated human asialoglycoprotein receptors recycle constitutively but are defective in coated pit-mediated endocytosis, dissociation, and delivery of ligand to lysosomes.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Yik JH, Saxena A, Weigel JA, Weigel PH", "reference": { "type": "PubMed", "id": "12171918", "url": "https://pubmed.ncbi.nlm.nih.gov/12171918" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein 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"Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 36, "end_pos": 36, "sequence_org": "C", "sequence_mut": "S", "comment": "Complete loss of palmitoylation.", "evidence": [ { "database": "UniProtKB", "id": "P07306", "url": "https://www.uniprot.org/uniprotkb/P07306" }, { "database": "PubMed", "id": "12171918", "url": "https://pubmed.ncbi.nlm.nih.gov/12171918" } ], "uniprot_canonical_ac": "P07306-1" } ], "record_id": "pubmed.12171918", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain.", "journal": "The Biochemical journal", "date": "2003", "authors": "Montiel MD, Krzewinski-Recchi MA, Delannoy P, Harduin-Lepers A", "reference": { "type": "PubMed", "id": "12678917", "url": "https://pubmed.ncbi.nlm.nih.gov/12678917" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11206-1", "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4", "gene_name": "ST3GAL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11203-1", "protein_name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "gene_name": "ST3GAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969X2-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "gene_name": "ST6GALNAC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43825-1", "protein_name": "Beta-1,3-galactosyltransferase 2", "gene_name": "B3GALT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C3-1", "protein_name": "Beta-1,3-galactosyltransferase 5", "gene_name": "B3GALT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "gene_name": "B4GALNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5Z6-1", "protein_name": "Beta-1,3-galactosyltransferase 1", "gene_name": "B3GALT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y274-1", "protein_name": "Type 2 lactosamine alpha-2,3-sialyltransferase", "gene_name": "ST3GAL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51993-1", "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6", "gene_name": "FUT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11128-1", "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5", "gene_name": "FUT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10981-1", "protein_name": "Galactoside alpha-(1,2)-fucosyltransferase 2", "gene_name": "FUT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96024-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3GALT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21217-1", "protein_name": "3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3", "gene_name": "FUT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22083-1", "protein_name": "Alpha-(1,3)-fucosyltransferase 4", "gene_name": "FUT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11130-1", "protein_name": "Alpha-(1,3)-fucosyltransferase 7", "gene_name": "FUT7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y231-1", "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "gene_name": "FUT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07911-1", "protein_name": "Uromodulin", "gene_name": "UMOD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12678917", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Differential binding properties of B7-H1 and B7-DC to programmed death-1.", "journal": "Biochemical and biophysical research communications", "date": "2003", "authors": "Youngnak P, Kozono Y, Kozono H, Iwai H, Otsuki N, Jin H, Omura K, Yagita H, Pardoll DM, Chen L, Azuma M", "reference": { "type": "PubMed", "id": "12893276", "url": "https://pubmed.ncbi.nlm.nih.gov/12893276" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ51-1", "protein_name": "Programmed cell death 1 ligand 2", "gene_name": "PDCD1LG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZQ7-1", "protein_name": "Programmed cell death 1 ligand 1", "gene_name": "CD274", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41240-1", "protein_name": "Tyrosine-protein kinase CSK", "gene_name": "CSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20036-1", "protein_name": "HLA class II histocompatibility antigen, DP alpha 1 chain", "gene_name": "HLA-DPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15116-1", "protein_name": "Programmed cell death protein 1", "gene_name": "PDCD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01737-1", "protein_name": "T cell receptor alpha variable 8-4", "gene_name": "TRAV8-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04437-1", "protein_name": "T cell receptor alpha variable 29/delta variable 5", "gene_name": "TRAV29DV5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A0A6YYK7-1", "protein_name": "T cell receptor alpha variable 19", "gene_name": "TRAV19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01920-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 1 chain", "gene_name": "HLA-DQB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01906-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 2 chain", "gene_name": "HLA-DQA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01911-1", "protein_name": "HLA class II histocompatibility antigen, DRB1 beta chain", "gene_name": "HLA-DRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04435-1", "protein_name": "T cell receptor beta variable 7-9", "gene_name": "TRBV7-9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01733-1", "protein_name": "T cell receptor beta variable 12-3", "gene_name": "TRBV12-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2A9-1", "protein_name": "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3", "gene_name": "B3GNT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01848-1", "protein_name": "T cell receptor alpha chain constant", "gene_name": "TRAC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01850-1", "protein_name": "T cell receptor beta constant 1", "gene_name": "TRBC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07766-1", "protein_name": "T-cell surface glycoprotein CD3 epsilon chain", "gene_name": "CD3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01909-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 1 chain", "gene_name": "HLA-DQA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04440-1", "protein_name": "HLA class II histocompatibility antigen, DP beta 1 chain", "gene_name": "HLA-DPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05538-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 2 chain", "gene_name": "HLA-DQB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13762-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 4 chain", "gene_name": "HLA-DRB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30154-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 5 chain", "gene_name": "HLA-DRB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01903-1", "protein_name": "HLA class II histocompatibility antigen, DR alpha chain", "gene_name": "HLA-DRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P79483-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 3 chain", "gene_name": "HLA-DRB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12893276", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.", "journal": "Glycobiology", "date": "2004", "authors": "Petrescu AJ, Milac AL, Petrescu SM, Dwek RA, Wormald MR", "reference": { "type": "PubMed", "id": "14514716", "url": "https://pubmed.ncbi.nlm.nih.gov/14514716" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "gene_name": "B4GALNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07911-1", "protein_name": "Uromodulin", "gene_name": "UMOD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14514716", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular cloning of the human beta1,4 N-acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain.", "journal": "Journal of biochemistry", "date": "2003", "authors": "Lo Presti L, Cabuy E, Chiricolo M, Dall'Olio F", "reference": { "type": "PubMed", "id": "14688233", "url": "https://pubmed.ncbi.nlm.nih.gov/14688233" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11206-1", "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4", "gene_name": "ST3GAL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11203-1", "protein_name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "gene_name": "ST3GAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969X2-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6", "gene_name": "ST6GALNAC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43825-1", "protein_name": "Beta-1,3-galactosyltransferase 2", "gene_name": "B3GALT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2C3-1", "protein_name": "Beta-1,3-galactosyltransferase 5", "gene_name": "B3GALT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "gene_name": "B4GALNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5Z6-1", "protein_name": "Beta-1,3-galactosyltransferase 1", "gene_name": "B3GALT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y274-1", "protein_name": "Type 2 lactosamine alpha-2,3-sialyltransferase", "gene_name": "ST3GAL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51993-1", "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6", "gene_name": "FUT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11128-1", "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5", "gene_name": "FUT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10981-1", "protein_name": "Galactoside alpha-(1,2)-fucosyltransferase 2", "gene_name": "FUT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96024-1", "protein_name": "Beta-1,3-galactosyltransferase 4", "gene_name": "B3GALT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21217-1", "protein_name": "3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3", "gene_name": "FUT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22083-1", "protein_name": "Alpha-(1,3)-fucosyltransferase 4", "gene_name": "FUT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11130-1", "protein_name": "Alpha-(1,3)-fucosyltransferase 7", "gene_name": "FUT7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y231-1", "protein_name": "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9", "gene_name": "FUT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07911-1", "protein_name": "Uromodulin", "gene_name": "UMOD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14688233", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.", "journal": "Nat. Biotechnol.", "date": "2004", "authors": "Brandenberger Ralph, Wei Henry, Zhang Sally, Lei Shirley, Murage Jaji, Fisk Gregory J, Li Yan, Xu Chunhui, Fang Rixun, Guegler Karl, Rao Mahendra S, Mandalam Ramumkar, Lebkowski Jane, Stanton Lawrence W", "reference": { "type": "PubMed", "id": "15146197", "url": "https://pubmed.ncbi.nlm.nih.gov/15146197" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MVM7-1", "protein_name": "Putative uncharacterized protein ENSP00000382790", "gene_name": "", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95445-1", "protein_name": "Apolipoprotein M", "gene_name": "APOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36404-1", "protein_name": "ADP-ribosylation factor-like protein 2", "gene_name": "ARL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NCS4-1", "protein_name": "Homeobox protein Nkx-2.6", "gene_name": "NKX2-6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15018-1", "protein_name": "Leukemia inhibitory factor", "gene_name": "LIF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CW18-1", "protein_name": "Serine protease 56", "gene_name": "PRSS56", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXM2-1", "protein_name": "BPTF-associated chromatin complex component 1", "gene_name": "BACC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJL9-1", "protein_name": "Zinc finger protein 69 homolog B", "gene_name": "ZFP69B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0Q3-1", "protein_name": "FXYD domain-containing ion transport regulator 6", "gene_name": "FXYD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03938-1", "protein_name": "Zinc finger protein 90", "gene_name": "ZNF90", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZ63-1", "protein_name": "Proline-rich protein 22", "gene_name": "PRR22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9F0-1", "protein_name": "N-acetylaspartate synthetase", "gene_name": "NAT8L", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15146197", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "gene_name": "B4GALNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07911-1", "protein_name": "Uromodulin", "gene_name": "UMOD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16317064", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin.", "journal": "The Journal of cell biology", "date": "2007", "authors": "Ling K, Bairstow SF, Carbonara C, Turbin DA, Huntsman DG, Anderson RA", "reference": { "type": "PubMed", "id": "17261850", "url": "https://pubmed.ncbi.nlm.nih.gov/17261850" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67812-1", "protein_name": "Signal peptidase complex catalytic subunit SEC11A", "gene_name": "SEC11A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12955-3", "protein_name": "Ankyrin-3", "gene_name": "ANK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09958-1", "protein_name": "Furin", "gene_name": "FURIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19784-1", "protein_name": "Casein kinase II subunit alpha'", "gene_name": "CSNK2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29122-1", "protein_name": "Proprotein convertase subtilisin/kexin type 6", "gene_name": "PCSK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKY4-1", "protein_name": "Protein O-mannosyl-transferase 2", "gene_name": "POMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A1-1", "protein_name": "Protein O-mannosyl-transferase 1", "gene_name": "POMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35222-1", "protein_name": "Catenin beta-1", "gene_name": "CTNNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27824-1", "protein_name": "Calnexin", "gene_name": "CANX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14923-1", "protein_name": "Junction plakoglobin", "gene_name": "JUP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEV1-1", "protein_name": "Casein kinase II subunit alpha 3", "gene_name": "CSNK2A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14697-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "GANAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12830-1", "protein_name": "Cadherin-1", "gene_name": "CDH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16549-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61009-1", "protein_name": "Signal peptidase complex subunit 3", "gene_name": "SPCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A9-1", "protein_name": "Signal peptidase complex subunit 1", "gene_name": "SPCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68400-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CSNK2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67870-1", "protein_name": "Casein kinase II subunit beta", "gene_name": "CSNK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14314-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PRKCSH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13724-1", "protein_name": "Mannosyl-oligosaccharide glucosidase", "gene_name": "MOGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY50-1", "protein_name": "Signal peptidase complex catalytic subunit SEC11C", "gene_name": "SEC11C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15005-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "SPCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A7KAX9-1", "protein_name": "Rho GTPase-activating protein 32", "gene_name": "ARHGAP32", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17261850", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q12955-3", "protein_name": "Ankyrin-3", "gene_name": "ANK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09958-1", "protein_name": "Furin", "gene_name": "FURIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19784-1", "protein_name": "Casein kinase II subunit alpha'", "gene_name": "CSNK2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29122-1", "protein_name": "Proprotein convertase subtilisin/kexin type 6", "gene_name": "PCSK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKY4-1", "protein_name": "Protein O-mannosyl-transferase 2", "gene_name": "POMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A1-1", "protein_name": "Protein O-mannosyl-transferase 1", "gene_name": "POMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35222-1", "protein_name": "Catenin beta-1", "gene_name": "CTNNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27824-1", "protein_name": "Calnexin", "gene_name": "CANX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14923-1", "protein_name": "Junction plakoglobin", "gene_name": "JUP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEV1-1", "protein_name": "Casein kinase II subunit alpha 3", "gene_name": "CSNK2A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14697-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "GANAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12830-1", "protein_name": "Cadherin-1", "gene_name": "CDH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16549-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 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"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11201-1", "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1", "gene_name": "ST3GAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11206-1", "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4", "gene_name": "ST3GAL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDV1-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3", "gene_name": "ST6GALNAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16842-1", "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2", "gene_name": "ST3GAL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJ37-1", "protein_name": "Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2", "gene_name": "ST6GALNAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15907-1", "protein_name": "Beta-galactoside alpha-2,6-sialyltransferase 1", "gene_name": "ST6GAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q11203-1", "protein_name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "gene_name": "ST3GAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4F1-1", "protein_name": "Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase", "gene_name": "ST6GALNAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y397-1", "protein_name": "Palmitoyltransferase ZDHHC9", "gene_name": "ZDHHC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKM7-1", "protein_name": "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase", "gene_name": "MAN1B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27824-1", "protein_name": "Calnexin", "gene_name": "CANX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z5G4-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "GOLGA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYC5-1", "protein_name": "Alpha-(1,6)-fucosyltransferase", "gene_name": "FUT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14697-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "GANAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIJ5-1", "protein_name": "Palmitoyltransferase ZDHHC2", "gene_name": "ZDHHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8X9-1", "protein_name": "Palmitoyltransferase ZDHHC11", "gene_name": "ZDHHC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5W0Z9-1", "protein_name": "Palmitoyltransferase ZDHHC20", "gene_name": "ZDHHC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC8-1", "protein_name": "Palmitoyltransferase ZDHHC8", "gene_name": "ZDHHC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14314-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PRKCSH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26572-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "gene_name": "MGAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16706-1", "protein_name": "Alpha-mannosidase 2", "gene_name": "MAN2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ53-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B", "gene_name": "MGAT4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13724-1", "protein_name": "Mannosyl-oligosaccharide glucosidase", "gene_name": "MOGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM8-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "MGAT4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM21-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A", "gene_name": "MGAT4A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22915798", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The expanding roles of the Sd(a)/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2.", "journal": "Biochimica et biophysica acta", "date": "2014", "authors": "Dall'Olio F, Malagolini N, Chiricolo M, Trinchera M, Harduin-Lepers A", "reference": { "type": "PubMed", "id": "24112972", "url": "https://pubmed.ncbi.nlm.nih.gov/24112972" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCJ2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "gene_name": "STT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHY0-1", "protein_name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "gene_name": "B4GALNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U3-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1", "gene_name": "MAGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13454-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3", "gene_name": "TUSC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07911-1", "protein_name": "Uromodulin", "gene_name": "UMOD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24112972", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The glucosyltransferase Xiantuan of the endoplasmic reticulum specifically affects E-Cadherin expression and is required for gastrulation movements in Drosophila.", "journal": "Developmental biology", "date": "2014", "authors": "Zhang Y, Kong D, Reichl L, Vogt N, Wolf F, Grosshans J", "reference": { "type": "PubMed", "id": "24681004", "url": "https://pubmed.ncbi.nlm.nih.gov/24681004" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67812-1", "protein_name": "Signal peptidase complex catalytic subunit SEC11A", "gene_name": "SEC11A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12955-3", "protein_name": "Ankyrin-3", "gene_name": "ANK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q24298-1", "protein_name": "DE-cadherin", "gene_name": "shg", "tax_name": "Fruit fly" }, { "uniprot_canonical_ac": "P09958-1", "protein_name": "Furin", "gene_name": "FURIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46977-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "gene_name": "STT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19784-1", "protein_name": "Casein kinase II subunit alpha'", "gene_name": "CSNK2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6T2-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "gene_name": "OST4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29122-1", "protein_name": "Proprotein convertase subtilisin/kexin type 6", "gene_name": "PCSK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P39656-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9W3V8-1", "protein_name": "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "xit", "tax_name": "Fruit fly" }, { "uniprot_canonical_ac": "P04844-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04843-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61803-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "DAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKY4-1", "protein_name": "Protein O-mannosyl-transferase 2", "gene_name": "POMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A1-1", "protein_name": "Protein O-mannosyl-transferase 1", "gene_name": "POMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35222-1", "protein_name": "Catenin beta-1", "gene_name": "CTNNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27824-1", "protein_name": "Calnexin", "gene_name": "CANX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14923-1", "protein_name": "Junction plakoglobin", "gene_name": "JUP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEV1-1", "protein_name": "Casein kinase II subunit alpha 3", "gene_name": "CSNK2A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14697-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "GANAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12830-1", "protein_name": "Cadherin-1", "gene_name": "CDH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16549-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61165-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TMEM258", "gene_name": "TMEM258", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61009-1", "protein_name": "Signal peptidase complex subunit 3", "gene_name": "SPCS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A9-1", "protein_name": "Signal peptidase complex subunit 1", "gene_name": "SPCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68400-1", "protein_name": "Casein kinase II subunit alpha", "gene_name": "CSNK2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67870-1", "protein_name": "Casein kinase II subunit beta", "gene_name": "CSNK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14314-1", "protein_name": "Glucosidase 2 subunit beta", "gene_name": "PRKCSH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13724-1", "protein_name": "Mannosyl-oligosaccharide glucosidase", "gene_name": "MOGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY50-1", "protein_name": "Signal peptidase complex catalytic subunit SEC11C", "gene_name": "SEC11C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15005-1", "protein_name": "Signal peptidase complex subunit 2", "gene_name": "SPCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A7KAX9-1", "protein_name": "Rho GTPase-activating protein 32", "gene_name": "ARHGAP32", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRP0", "url": "https://www.uniprot.org/uniprotkb/Q9NRP0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24681004", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 34 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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