[ { "title": "Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases.", "journal": "J. Mol. Biol.", "date": "1994", "authors": "Hanes J, von der Kammer H, Klaudiny J, Scheit KH", "reference": { "type": "PubMed", "id": "7990150", "url": "https://pubmed.ncbi.nlm.nih.gov/7990150" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P49761-1", "protein_name": "Dual specificity protein kinase CLK3", "gene_name": "CLK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49760-1", "protein_name": "Dual specificity protein kinase CLK2", "gene_name": "CLK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22518-1", "protein_name": "Dual specificity protein kinase CLK1", "gene_name": "Clk1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P49759-1", "protein_name": "Dual specificity protein kinase CLK1", "gene_name": "CLK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P49761", "url": "https://www.uniprot.org/uniprotkb/P49761" } ], "common_name": "Human", "glygen_name": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A CLN5 mutation causing an atypical neuronal ceroid lipofuscinosis of juvenile onset.", "journal": "Neurology", "date": "2005", "authors": "Pineda-Trujillo N, Cornejo W, Carrizosa J, Wheeler RB, Munera S, Valencia A, Agudelo-Arango J, Cogollo A, Anderson G, Bedoya G, Mole SE, Ruiz-Linares A", "reference": { "type": "PubMed", "id": "15728307", "url": "https://pubmed.ncbi.nlm.nih.gov/15728307" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75503-1", "protein_name": "Bis(monoacylglycero)phosphate synthase CLN5", "gene_name": "CLN5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75503", "url": "https://www.uniprot.org/uniprotkb/O75503" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15728307", "abstract": 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MC, Guimaraes A, Ferreira JC, Canas N, Cabral P, Ribeiro MG", "reference": { "type": "PubMed", "id": "16814585", "url": "https://pubmed.ncbi.nlm.nih.gov/16814585" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75503-1", "protein_name": "Bis(monoacylglycero)phosphate synthase CLN5", "gene_name": "CLN5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75503", "url": "https://www.uniprot.org/uniprotkb/O75503" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16814585", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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No alterations in secondary structure and thermal stability.", "evidence": [ { "database": "UniProtKB", "id": "O75503", "url": "https://www.uniprot.org/uniprotkb/O75503" }, { "database": "PubMed", "id": "35427157", "url": "https://pubmed.ncbi.nlm.nih.gov/35427157" }, { "database": "PubMed", "id": "37708259", "url": "https://pubmed.ncbi.nlm.nih.gov/37708259" } ], "uniprot_canonical_ac": "O75503-1" }, { "start_pos": 318, "end_pos": 319, "sequence_org": "HK", "sequence_mut": "EE", "comment": "Weakens vesicular bis(monoacylglycero)phosphate binding. 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis.", "journal": "Nature genetics", "date": "1998", "authors": "Savukoski M, Klockars T, Holmberg V, Santavuori P, Lander ES, Peltonen L", "reference": { "type": "PubMed", "id": "9662406", "url": "https://pubmed.ncbi.nlm.nih.gov/9662406" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75503-1", "protein_name": "Bis(monoacylglycero)phosphate synthase CLN5", "gene_name": "CLN5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75503", "url": "https://www.uniprot.org/uniprotkb/O75503" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "snv": [ { "evidence": [ { "id": "rs28940280", "database": "dbSNP", 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Signs and symptoms of the condition generally develop between ages 4.5 and 7 years, although later onset cases have been reported. Affected people may experience loss of muscle coordination (ataxia), seizures that do not respond to medications, muscle twitches (myoclonus), visual impairment, and cognitive/motor decline. It occurs predominantly in the Finnish population. CLN5-NCL is caused by changes (mutations) in the CLN5 gene and is inherited in an autosomal recessive manner. Treatment options are limited to therapies that can help relieve some of the symptoms." }, { "id": "MONDO:0009745", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009745", "name": "CLN5", "description": "" }, { "id": "MONDO:0009745", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009745", "name": "CLN5 neuronal ceroid lipofuscinosis", "description": "" }, { "id": "MONDO:0009745", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009745", "name": "ceroid lipofuscinosis, neuronal, type 5", "description": "" }, { "id": "MONDO:0009745", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009745", "name": "neuronal ceroid lipofuscinosis caused by mutation in CLN5", "description": "" }, { "id": "MONDO:0009745", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009745", "name": "neuronal ceroid lipofuscinosis type 5", "description": "" }, { "id": "MONDO:0009745", 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"title": "Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain.", "journal": "Blood", "date": "1991", "authors": "Baier L J, Hannibal M C, Hanley E W, Nabel G J", "reference": { "type": "PubMed", "id": "1678287", "url": "https://pubmed.ncbi.nlm.nih.gov/1678287" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P09629-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "HOXB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P09629", "url": "https://www.uniprot.org/uniprotkb/P09629" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1678287", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)", "date": "2023", "authors": "Ji J, Xiong C, Peng J, Zhang N, Zhang Y, Yang H, Zhu W", "reference": { "type": "PubMed", "id": "36823512", "url": "https://pubmed.ncbi.nlm.nih.gov/36823512" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P09629-1", "protein_name": "Homeobox protein Hox-B7", "gene_name": "HOXB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P09629", "url": "https://www.uniprot.org/uniprotkb/P09629" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36823512", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", 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"Yang SW, Huang X, Lin W, Min J, Miller DJ, Mayasundari A, Rodrigues P, Griffith EC, Gee CT, Li L, Li W, Lee RE, Rankovic Z, Chen T, Potts PR", "reference": { "type": "PubMed", "id": "33004795", "url": "https://pubmed.ncbi.nlm.nih.gov/33004795" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P43364-1", "protein_name": "Melanoma-associated antigen 11", "gene_name": "MAGEA11", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P43364", "url": "https://www.uniprot.org/uniprotkb/P43364" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33004795", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma.", "journal": "Nature", "date": "2021-08", "authors": "Oliveira Giacomo, Stromhaug Kari, Klaeger Susan, Kula Tomasz, Frederick Dennie T, Le Phuong M, Forman Juliet, Huang Teddy, Li Shuqiang, Zhang Wandi, Xu Qikai, Cieri Nicoletta, Clauser Karl R, Shukla Sachet A, Neuberg Donna, Justesen Sune, MacBeath Gavin, Carr Steven A, Fritsch Edward F, Hacohen Nir, Sade-Feldman Moshe, Livak Kenneth J, Boland Genevieve M, Ott Patrick A, Keskin Derin B, Wu Catherine J", "reference": { "type": "PubMed", "id": "34290406", "url": "https://pubmed.ncbi.nlm.nih.gov/34290406" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P43364-1", "protein_name": "Melanoma-associated antigen 11", "gene_name": "MAGEA11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15369-1", "protein_name": "Elongin-C", "gene_name": "ELOC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43362-1", "protein_name": "Melanoma-associated antigen 9", "gene_name": "MAGEA9B; MAGEA9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF1-1", "protein_name": "Melanoma-associated antigen D2", "gene_name": "MAGED2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78395-1", "protein_name": "Melanoma antigen preferentially expressed in tumors", "gene_name": "PRAME", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43358-1", "protein_name": "Melanoma-associated antigen 4", "gene_name": "MAGEA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBF1-1", "protein_name": "Melanoma-associated antigen C2", "gene_name": "MAGEC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43365-1", "protein_name": "Melanoma-associated antigen 12", "gene_name": "MAGEA12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43360-1", "protein_name": "Melanoma-associated antigen 6", "gene_name": "MAGEA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14679-1", "protein_name": "Tyrosinase", "gene_name": "TYR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6D5-1", "protein_name": "Brefeldin A-inhibited guanine nucleotide-exchange protein 2", "gene_name": "ARFGEF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46777-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "RPL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40967-1", "protein_name": "Melanocyte protein PMEL", "gene_name": "PMEL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40126-1", "protein_name": 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