[ { "title": "Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2007", "authors": "Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM", "reference": { "type": "PubMed", "id": "17330888", "url": "https://pubmed.ncbi.nlm.nih.gov/17330888" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92482-1", "protein_name": "Aquaporin-3", "gene_name": "AQP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16144-1", "protein_name": "Integrin beta-4", "gene_name": "ITGB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3V2T4-1", "protein_name": "Keratinocyte differentiation-associated protein", "gene_name": "Krtdap", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P20930-1", "protein_name": "Filaggrin", "gene_name": "FLG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y337-1", "protein_name": "Kallikrein-5", "gene_name": "KLK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04264-1", "protein_name": "Keratin, type II cytoskeletal 1", "gene_name": "KRT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13647-1", "protein_name": "Keratin, type II cytoskeletal 5", "gene_name": "KRT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWP8-1", "protein_name": "Suprabasin", "gene_name": "SBSN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P253-1", "protein_name": "Dermokine", "gene_name": "Dmkn", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6E0U4-1", "protein_name": "Dermokine", "gene_name": "DMKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1N4-1", "protein_name": "Keratin, type II cytoskeletal 78", "gene_name": "KRT78", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H3D4-1", "protein_name": "Tumor protein 63", "gene_name": "TP63", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZT1-1", "protein_name": "Calmodulin-like protein 5", "gene_name": "CALML5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31944-1", "protein_name": "Caspase-14", "gene_name": "CASP14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49757-1", "protein_name": "Protein numb homolog", "gene_name": "NUMB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49862-1", "protein_name": "Kallikrein-7", "gene_name": "KLK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23490-1", "protein_name": "Loricrin", "gene_name": "LORICRIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8CIT9-1", "protein_name": "Suprabasin", "gene_name": "Sbsn", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P13645-1", "protein_name": "Keratin, type I cytoskeletal 10", "gene_name": "KRT10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02533-1", "protein_name": "Keratin, type I cytoskeletal 14", "gene_name": "KRT14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60985-1", "protein_name": "Keratinocyte differentiation-associated protein", "gene_name": "KRTDAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35326-1", "protein_name": "Small proline-rich protein 2A", "gene_name": "SPRR2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IFZ6-1", "protein_name": "Keratin, type II cytoskeletal 1b", "gene_name": "Krt77", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ38-1", "protein_name": "Serine protease inhibitor Kazal-type 5", "gene_name": "SPINK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P47929-1", "protein_name": "Galectin-7", "gene_name": "LGALS7B; LGALS7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35030-1", "protein_name": "Trypsin-3", "gene_name": "PRSS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00548-1", "protein_name": "Delta-like protein 1", "gene_name": "DLL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01469-1", "protein_name": "Fatty acid-binding protein 5", "gene_name": "FABP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08727-1", "protein_name": "Keratin, type I cytoskeletal 19", "gene_name": "KRT19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05556-1", "protein_name": "Integrin beta-1", "gene_name": "ITGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T749-1", "protein_name": "Keratinocyte proline-rich protein", "gene_name": "KPRP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75712-1", "protein_name": "Gap junction beta-3 protein", "gene_name": "GJB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UVK1-1", "protein_name": "Chondroitin sulfate proteoglycan 4", "gene_name": "CSPG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23229-1", "protein_name": "Integrin alpha-6", "gene_name": "ITGA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BPY8-1", "protein_name": "Homeodomain-only protein", "gene_name": "HOPX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I5-1", "protein_name": "Keratin, type I cytoskeletal 24", "gene_name": "KRT24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96JA1-1", "protein_name": "Leucine-rich repeats and immunoglobulin-like domains protein 1", "gene_name": "LRIG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46937-1", "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19012-1", "protein_name": "Keratin, type I cytoskeletal 15", "gene_name": "KRT15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07476-1", "protein_name": "Involucrin", "gene_name": "IVL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNQ0-1", "protein_name": "Broad substrate specificity ATP-binding cassette transporter ABCG2", "gene_name": "ABCG2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17330888", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity.", "journal": "Cancer cell", "date": "2007", "authors": "Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ", "reference": { "type": "PubMed", "id": "17349580", "url": "https://pubmed.ncbi.nlm.nih.gov/17349580" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17349580", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.", "journal": "Molecular biology of the cell", "date": "2007", "authors": "Doray B, Lee I, Knisely J, Bu G, Kornfeld S", "reference": { "type": "PubMed", "id": "17360967", "url": "https://pubmed.ncbi.nlm.nih.gov/17360967" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane 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"uniprot_canonical_ac": "Q13098-4", "protein_name": "COP9 signalosome complex subunit 1", "gene_name": "GPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT78-1", "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "COPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15843-1", "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "NEDD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II 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"Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17360967", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17372273", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"Steroid hormone rapid signaling: the pivotal role of S-palmitoylation.", "journal": "IUBMB life", "date": "2006", "authors": "Marino M, Ascenzi P", "reference": { "type": "PubMed", "id": "17424910", "url": "https://pubmed.ncbi.nlm.nih.gov/17424910" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 737, "end_pos": 737, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": 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"url": "https://pubmed.ncbi.nlm.nih.gov/17456551" } ], "site_lbl": "Tyr54", "uniprot_canonical_ac": "P49407-1" } ], "record_id": "pubmed.17456551", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel AAK1 splice variant functions at multiple steps of the endocytic pathway.", "journal": "Molecular biology of the cell", "date": "2007", "authors": "Henderson DM, Conner SD", "reference": { "type": "PubMed", "id": "17494869", "url": "https://pubmed.ncbi.nlm.nih.gov/17494869" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": 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"uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17494869", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], 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}, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": 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"Human" }, { "uniprot_canonical_ac": "O14656-1", "protein_name": "Torsin-1A", "gene_name": "TOR1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW8-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "COPS7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99627-1", "protein_name": "COP9 signalosome complex subunit 8", "gene_name": "COPS8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9Q2-1", "protein_name": "COP9 signalosome complex subunit 7b", "gene_name": "COPS7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13098-4", "protein_name": "COP9 signalosome complex subunit 1", "gene_name": "GPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT78-1", "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "COPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15843-1", "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "NEDD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": "Ubiquilin-2", "gene_name": "UBQLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17522231", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells.", "journal": "Endocrinology", "date": "2007", "authors": "Song RX, Zhang Z, Chen Y, Bao Y, Santen RJ", "reference": { "type": "PubMed", "id": "17525128", "url": "https://pubmed.ncbi.nlm.nih.gov/17525128" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62873-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "gene_name": "GNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63211-1", "protein_name": "Guanine nucleotide-binding protein G(T) subunit gamma-T1", "gene_name": "GNGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59768-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2", "gene_name": "GNG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60262-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7", "gene_name": "GNG7", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MTJ3-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "GNAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50150-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "gene_name": "GNG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50151-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "gene_name": "GNG10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2W3-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13", "gene_name": "GNG13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05397-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A conserved mechanism for steroid receptor translocation to the plasma membrane.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Pedram A, Razandi M, Sainson RC, Kim JK, Hughes CC, Levin ER", "reference": { "type": "PubMed", "id": "17535799", "url": "https://pubmed.ncbi.nlm.nih.gov/17535799" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62873-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "gene_name": "GNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63211-1", "protein_name": "Guanine 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"Matrilysin", "gene_name": "MMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04792-1", "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29474-1", "protein_name": "Nitric oxide synthase 3", "gene_name": "NOS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63218-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "gene_name": "GNG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99873-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "PRMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16520-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "gene_name": "GNB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04899-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "gene_name": "GNAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14780-1", "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK08-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "gene_name": "GNG8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBI6-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "gene_name": "GNG12", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14775-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-5", "gene_name": "GNB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": "GNG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14610-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2", "gene_name": "GNGT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08254-1", "protein_name": "Stromelysin-1", "gene_name": "MMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature.", "journal": "Structure (London, England : 1993)", "date": "2007", "authors": "Henne WM, Kent HM, Ford MG, Hegde BG, Daumke O, Butler PJ, Mittal R, Langen R, Evans PR, McMahon HT", "reference": { "type": "PubMed", "id": "17540576", "url": "https://pubmed.ncbi.nlm.nih.gov/17540576" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", 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"protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", 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"Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and characterization of novel spliced variants of neuregulin 4 in prostate cancer.", "journal": "Clinical cancer research : an official journal of the American Association for Cancer Research", "date": "2007", "authors": "Hayes NV, Blackburn E, Smart LV, Boyle MM, Russell GA, Frost TM, Morgan BJ, Baines AJ, Gullick WJ", "reference": { "type": "PubMed", "id": "17545517", "url": "https://pubmed.ncbi.nlm.nih.gov/17545517" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SNX9 couples actin assembly to phosphoinositide signals and is required for membrane remodeling during endocytosis.", "journal": "Developmental cell", "date": "2007", "authors": "Yarar D, Waterman-Storer CM, Schmid SL", "reference": { "type": "PubMed", "id": "17609109", "url": "https://pubmed.ncbi.nlm.nih.gov/17609109" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17609109", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 129 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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the phosphoinositide 3-kinase catalytic subunit.", "journal": "Science (New York, N.Y.)", "date": "2007", "authors": "Miled N, Yan Y, Hon WC, Perisic O, Zvelebil M, Inbar Y, Schneidman-Duhovny D, Wolfson HJ, Backer JM, Williams RL", "reference": { "type": "PubMed", "id": "17626883", "url": "https://pubmed.ncbi.nlm.nih.gov/17626883" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15391-1", "protein_name": "B-lymphocyte antigen CD19", "gene_name": "CD19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32871-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Bovine" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "NRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5UE93-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6", "gene_name": "PIK3R6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16620-1", "protein_name": "BDNF/NT-3 growth factors receptor", "gene_name": "NTRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48736-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUJ8-1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": 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{ "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.", "journal": "The Journal of clinical investigation", "date": "2007", "authors": "Groenestege WM, Thebault S, van der Wijst J, van den Berg D, Janssen R, Tejpar S, van den Heuvel LP, van Cutsem E, Hoenderop JG, Knoers NV, Bindels RJ", "reference": { "type": "PubMed", "id": "17671655", "url": "https://pubmed.ncbi.nlm.nih.gov/17671655" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": 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"uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17762867", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q14CB8-1", "protein_name": "Rho GTPase-activating protein 19", "gene_name": "ARHGAP19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QB1-2", "protein_name": "Rho GTPase-activating protein 7", "gene_name": "DLC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2F6-1", "protein_name": "Rho GTPase-activating protein 20", "gene_name": "ARHGAP20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BST9-1", "protein_name": "Rhotekin", "gene_name": "RTKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P4F7-1", "protein_name": "Rho GTPase-activating protein 11A", "gene_name": "ARHGAP11A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N392-1", "protein_name": "Rho GTPase-activating protein 18", "gene_name": "ARHGAP18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRY4-1", "protein_name": "Rho GTPase-activating protein 35", "gene_name": "ARHGAP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2N2-1", "protein_name": "Rho GTPase-activating protein 28", "gene_name": "ARHGAP28", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75116-1", "protein_name": "Rho-associated protein kinase 2", "gene_name": "ROCK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5TG30-1", "protein_name": "Rho GTPase-activating protein 40", "gene_name": "ARHGAP40", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P0U3-1", "protein_name": "Sentrin-specific protease 1", "gene_name": "SENP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94933-1", "protein_name": "SLIT and NTRK-like protein 3", "gene_name": "SLITRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZW31-1", "protein_name": "Rho GTPase-activating protein SYDE1", "gene_name": "SYDE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UH65-1", "protein_name": "Switch-associated protein 70", "gene_name": "SWAP70", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53LP3-1", "protein_name": "Ankyrin repeat domain-containing protein SOWAHC", "gene_name": "SOWAHC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08134-1", "protein_name": "Rho-related GTP-binding protein RhoC", "gene_name": "RHOC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P227-1", "protein_name": "Rho GTPase-activating protein 23", "gene_name": "ARHGAP23", "tax_name": "Human" }, { "uniprot_canonical_ac": "P85298-1", "protein_name": "Rho GTPase-activating protein 8", "gene_name": "ARHGAP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q17R89-1", "protein_name": "Rho GTPase-activating protein 44", "gene_name": "ARHGAP44", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWW6-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "ARHGAP12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53QZ3-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "ARHGAP15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBH0-1", "protein_name": "Rho-related GTP-binding protein RhoF", "gene_name": "RHOF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13017-1", "protein_name": "Rho GTPase-activating protein 5", "gene_name": "ARHGAP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42331-1", "protein_name": "Rho GTPase-activating protein 25", "gene_name": "ARHGAP25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3KRB8-1", "protein_name": "Inactive Rho GTPase-activating protein 11B", "gene_name": "ARHGAP11B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q52LW3-1", "protein_name": "Rho GTPase-activating protein 29", "gene_name": "ARHGAP29", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUC4-1", "protein_name": "Rhophilin-2", "gene_name": "RHPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C0H5-1", "protein_name": "Rho GTPase-activating protein 39", "gene_name": "ARHGAP39", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M1Z3-1", "protein_name": "Rho GTPase-activating protein 31", "gene_name": "ARHGAP31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00161-1", "protein_name": "Synaptosomal-associated protein 23", "gene_name": "SNAP23", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94991-1", "protein_name": "SLIT and NTRK-like protein 5", "gene_name": "SLITRK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2G2-1", "protein_name": "STE20-like serine/threonine-protein kinase", "gene_name": "SLK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UXY1-1", "protein_name": "BAR/IMD domain-containing adapter protein 2-like 2", "gene_name": "BAIAP2L2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96N67-1", "protein_name": "Dedicator of cytokinesis protein 7", "gene_name": "DOCK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1I0-1", "protein_name": "Dedicator of cytokinesis protein 4", "gene_name": "DOCK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JSL3-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "DOCK11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7D0-1", "protein_name": "Dedicator of cytokinesis protein 5", "gene_name": "DOCK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75962-1", "protein_name": "Triple functional domain protein", "gene_name": "TRIO", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAA9-1", "protein_name": "Vang-like protein 1", "gene_name": "VANGL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BY6-1", "protein_name": "Dedicator of cytokinesis protein 10", "gene_name": "DOCK10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HY6-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "DDRGK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14344-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha-13", "gene_name": "GNA13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UH62-1", "protein_name": "Armadillo repeat-containing X-linked protein 3", "gene_name": "ARMCX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z628-1", "protein_name": "Neuroepithelial cell-transforming gene 1 protein", "gene_name": "NET1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IW93-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "ARHGEF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DR7-1", "protein_name": "Rho guanine nucleotide exchange factor 26", "gene_name": "ARHGEF26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q58EX7-1", "protein_name": "Puratrophin-1", "gene_name": "PLEKHG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQB8-1", "protein_name": "BAR/IMD domain-containing adapter protein 2", "gene_name": "BAIAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P286-1", "protein_name": "Serine/threonine-protein kinase PAK 5", "gene_name": "PAK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00587-1", "protein_name": "Cdc42 effector protein 1", "gene_name": "CDC42EP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11274-1", "protein_name": "Breakpoint cluster region protein", "gene_name": "BCR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P47756-2", "protein_name": "F-actin-capping protein subunit beta", "gene_name": "CAPZB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P5Z2-1", "protein_name": "Serine/threonine-protein kinase N3", "gene_name": "PKN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRR3-1", "protein_name": "CDC42 small effector protein 2", "gene_name": "CDC42SE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99819-1", "protein_name": "Rho GDP-dissociation inhibitor 3", "gene_name": "ARHGDIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96NT0-1", "protein_name": "Vacuolar ATPase assembly protein VMA22", "gene_name": "VMA22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKI2-1", "protein_name": "Cdc42 effector protein 3", "gene_name": "CDC42EP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52757-1", "protein_name": "Beta-chimaerin", "gene_name": "CHN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75914-1", "protein_name": "Serine/threonine-protein kinase PAK 3", "gene_name": "PAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L576-1", "protein_name": "Cytoplasmic FMR1-interacting protein 1", "gene_name": "CYFIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96F07-1", "protein_name": "Cytoplasmic FMR1-interacting protein 2", "gene_name": "CYFIP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29317-1", "protein_name": "Ephrin type-A receptor 2", "gene_name": "EPHA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04839-1", "protein_name": "NADPH oxidase 2", "gene_name": "CYBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AC1-1", "protein_name": "Fermitin family homolog 2", "gene_name": "FERMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13576-1", "protein_name": "Ras GTPase-activating-like protein IQGAP2", "gene_name": "IQGAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VI3-1", "protein_name": "Ras GTPase-activating-like protein IQGAP3", "gene_name": "IQGAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78504-1", "protein_name": "Protein jagged-1", "gene_name": "JAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UDY2-1", "protein_name": "Tight junction protein 2", "gene_name": "TJP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15068-1", "protein_name": "Guanine nucleotide exchange factor DBS", "gene_name": "MCF2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13613-1", "protein_name": "Phosphatidylinositol-3-phosphate phosphatase MTMR1", "gene_name": "MTMR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10911-1", "protein_name": "Proto-oncogene DBL", "gene_name": "MCF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60229-1", "protein_name": "Kalirin", "gene_name": "KALRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y597-1", "protein_name": "BTB/POZ domain-containing protein KCTD3", "gene_name": "KCTD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2I1-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6S8J3-1", "protein_name": "POTE ankyrin domain family member E", "gene_name": "POTEE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPY6-1", "protein_name": "Actin-binding protein WASF3", "gene_name": "WASF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3M8-1", "protein_name": "StAR-related lipid transfer protein 13", "gene_name": "STARD13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14578-1", "protein_name": "Citron Rho-interacting kinase", "gene_name": "CIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y512-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "SAMM50", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96M96-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4", "gene_name": "FGD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4F1-1", "protein_name": "FERM, ARHGEF and pleckstrin domain-containing protein 1", "gene_name": "FARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVF7-1", "protein_name": "Formin-like protein 3", "gene_name": "FMNL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNL6-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 5", "gene_name": "FGD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z6J4-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 2", "gene_name": "FGD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PY5-1", "protein_name": "Formin-like protein 2", "gene_name": "FMNL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98174-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 1", "gene_name": "FGD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQU5-1", "protein_name": "Serine/threonine-protein kinase PAK 6", "gene_name": "PAK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42166-1", "protein_name": "Lamina-associated polypeptide 2, isoform alpha", "gene_name": "TMPO", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T2T1-1", "protein_name": "MAGUK p55 subfamily member 7", "gene_name": "MPP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IAA8-1", "protein_name": "Ragulator complex protein LAMTOR1", "gene_name": "LAMTOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95292-1", "protein_name": "Vesicle-associated membrane protein-associated protein B/C", "gene_name": "VAPB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94988-4", "protein_name": "Protein FAM13A", "gene_name": "FAM13A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T8D3-1", "protein_name": "Acyl-CoA-binding domain-containing protein 5", "gene_name": "ACBD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07890-1", "protein_name": "Son of sevenless homolog 2", "gene_name": "SOS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12979-1", "protein_name": "Active breakpoint cluster region-related protein", "gene_name": "ABR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68032-1", "protein_name": "Actin, alpha cardiac muscle 1", "gene_name": "ACTC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52735-1", "protein_name": "Guanine nucleotide exchange factor VAV2", "gene_name": "VAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0H5-1", "protein_name": "Rac GTPase-activating protein 1", "gene_name": "RACGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12814-1", "protein_name": "Alpha-actinin-1", "gene_name": "ACTN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92974-1", "protein_name": "Rho guanine nucleotide exchange factor 2", "gene_name": "ARHGEF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15758-1", "protein_name": "Neutral amino acid transporter B(0)", "gene_name": "SLC1A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60953-2", "protein_name": "Cell division control protein 42 homolog", "gene_name": "CDC42", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2A7-1", "protein_name": "Nck-associated protein 1", "gene_name": "NCKAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14598-1", "protein_name": "Neutrophil cytosol factor 1", "gene_name": "NCF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14155-4", "protein_name": "Rho guanine nucleotide exchange factor 7", "gene_name": "ARHGEF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50402-1", "protein_name": "Emerin", "gene_name": "EMD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4E7-1", "protein_name": "Differentially expressed in FDCP 6 homolog", "gene_name": "DEF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42768-1", "protein_name": "Actin nucleation-promoting factor WAS", "gene_name": "WAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q68EM7-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14923-1", "protein_name": "Junction plakoglobin", "gene_name": "JUP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96N96-1", "protein_name": "Spermatogenesis-associated protein 13", "gene_name": "SPATA13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SJ2-1", "protein_name": "Amphoterin-induced protein 2", "gene_name": "AMIGO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15311-1", "protein_name": "RalA-binding protein 1", "gene_name": "RALBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14160-3", "protein_name": "Protein scribble homolog", "gene_name": "SCRIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12802-1", "protein_name": "A-kinase anchor protein 13", "gene_name": "AKAP13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP61-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 3", "gene_name": "ARFGAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02952-1", "protein_name": "A-kinase anchor protein 12", "gene_name": "AKAP12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKG1-1", "protein_name": "DCC-interacting protein 13-alpha", "gene_name": "APPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05556-1", "protein_name": "Integrin beta-1", "gene_name": "ITGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM8-1", "protein_name": "Sec1 family domain-containing protein 1", "gene_name": "SCFD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13190-1", "protein_name": "Syntaxin-5", "gene_name": "STX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13498-1", "protein_name": "Cytochrome b-245 light chain", "gene_name": "CYBA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBC3-1", "protein_name": "SH3KBP1-binding protein 1", "gene_name": "SHKBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94887-1", "protein_name": "FERM, ARHGEF and pleckstrin domain-containing protein 2", "gene_name": "FARP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFA2-1", "protein_name": "NADPH oxidase organizer 1", "gene_name": "NOXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N264-1", "protein_name": "Rho GTPase-activating protein 24", "gene_name": "ARHGAP24", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95466-1", "protein_name": "Formin-like protein 1", "gene_name": "FMNL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YQ8-1", "protein_name": "Copine-8", "gene_name": "CPNE8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JSP0-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 3", "gene_name": "FGD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKW4-1", "protein_name": "Guanine nucleotide exchange factor VAV3", "gene_name": "VAV3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRR9-1", "protein_name": "Rho GTPase-activating protein 9", "gene_name": "ARHGAP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14559-1", "protein_name": "Rho GTPase-activating protein 33", "gene_name": "ARHGAP33", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CS3-1", "protein_name": "FAS-associated factor 2", "gene_name": "FAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PX9-1", "protein_name": "Pleckstrin homology domain-containing family G member 4B", "gene_name": "PLEKHG4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TF74-1", "protein_name": "WAS/WASL-interacting protein family member 2", "gene_name": "WIPF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52565-1", "protein_name": "Rho GDP-dissociation inhibitor 1", "gene_name": "ARHGDIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43295-1", "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3", "gene_name": "SRGAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14161-1", "protein_name": "ARF GTPase-activating protein GIT2", "gene_name": "GIT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "I6L899-1", "protein_name": "Golgin subfamily A member 8R", "gene_name": "GOLGA8R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NGB9-1", "protein_name": "WAS/WASL-interacting protein family member 3", "gene_name": "WIPF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51572-1", "protein_name": "B-cell receptor-associated protein 31", "gene_name": "BCAP31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86UP2-1", "protein_name": "Kinectin", "gene_name": "KTN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6W5-1", "protein_name": "Actin-binding protein WASF2", "gene_name": "WASF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHR4-1", "protein_name": "BAR/IMD domain-containing adapter protein 2-like 1", "gene_name": "BAIAP2L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6XZF7-1", "protein_name": "Dynamin-binding protein", "gene_name": "DNMBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92608-1", "protein_name": "Dedicator of cytokinesis protein 2", "gene_name": "DOCK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H3Q1-1", "protein_name": "Cdc42 effector protein 4", "gene_name": "CDC42EP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8V3-1", "protein_name": "Protein ECT2", "gene_name": "ECT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92558-1", "protein_name": "Actin-binding protein WASF1", "gene_name": "WASF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14126-1", "protein_name": "Desmoglein-2", "gene_name": "DSG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60610-1", "protein_name": "Protein diaphanous homolog 1", "gene_name": "DIAPH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60879-1", "protein_name": "Protein diaphanous homolog 2", "gene_name": "DIAPH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSV4-3", "protein_name": "Protein diaphanous homolog 3", "gene_name": "DIAPH3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5S2-1", "protein_name": "Serine/threonine-protein kinase MRCK beta", "gene_name": "CDC42BPB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y07-1", "protein_name": "Serine/threonine-protein kinase VRK2", "gene_name": "VRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "B2RTY4-1", "protein_name": "Unconventional myosin-IXa", "gene_name": "MYO9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15080-1", "protein_name": "Neutrophil cytosol factor 4", "gene_name": "NCF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13459-1", "protein_name": "Unconventional myosin-IXb", "gene_name": "MYO9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43121-1", "protein_name": "Cell surface glycoprotein MUC18", "gene_name": "MCAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55160-1", "protein_name": "Nck-associated protein 1-like", "gene_name": "NCKAP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L390-1", "protein_name": "Pleckstrin homology domain-containing family G member 3", "gene_name": "PLEKHG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P9-1", "protein_name": "Pleckstrin homology domain-containing family G member 2", "gene_name": "PLEKHG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94827-5", "protein_name": "Pleckstrin homology domain-containing family G member 5", "gene_name": "PLEKHG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1A4S6-1", "protein_name": "Rho GTPase-activating protein 10", "gene_name": "ARHGAP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULL1-1", "protein_name": "Pleckstrin homology domain-containing family G member 1", "gene_name": "PLEKHG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q70Z35-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein", "gene_name": "PREX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z6I6-1", "protein_name": "Rho GTPase-activating protein 30", "gene_name": "ARHGAP30", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUM4-1", "protein_name": "Rho GTPase-activating protein 27", "gene_name": "ARHGAP27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30519-1", "protein_name": "Heme oxygenase 2", "gene_name": "HMOX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X4-1", "protein_name": "Soluble lamin-associated protein of 75 kDa", "gene_name": "FAM169A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16513-1", "protein_name": "Serine/threonine-protein kinase N2", "gene_name": "PKN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51149-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "RAB7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94804-1", "protein_name": "Serine/threonine-protein kinase 10", "gene_name": "STK10", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N103-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "TAGAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q658P3-1", "protein_name": "Metalloreductase STEAP3", "gene_name": "STEAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92502-1", "protein_name": "StAR-related lipid transfer protein 8", "gene_name": "STARD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VT97-1", "protein_name": "Rho GTPase-activating protein SYDE2", "gene_name": "SYDE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVF5-1", "protein_name": "Rho guanine nucleotide exchange factor TIAM2", "gene_name": "TIAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15904-1", "protein_name": "V-type proton ATPase subunit S1", "gene_name": "ATP6AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P80723-1", "protein_name": "Brain acid soluble protein 1", "gene_name": "BASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUW1-1", "protein_name": "Protein BRICK1", "gene_name": "BRK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A096LP49-1", "protein_name": "Coiled-coil domain-containing protein 187", "gene_name": "CCDC187", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14613-1", "protein_name": "Cdc42 effector protein 2", "gene_name": "CDC42EP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNA1-1", "protein_name": "Rho GTPase-activating protein 26", "gene_name": "ARHGAP26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14739-1", "protein_name": "Delta(14)-sterol reductase LBR", "gene_name": "LBR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZY7-1", "protein_name": "Cdc42 effector protein 5", "gene_name": "CDC42EP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6NZI2-1", "protein_name": "Caveolae-associated protein 1", "gene_name": "CAVIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16584-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 11", "gene_name": "MAP3K11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VT25-1", "protein_name": "Serine/threonine-protein kinase MRCK alpha", "gene_name": "CDC42BPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z5H3-1", "protein_name": "Rho GTPase-activating protein 22", "gene_name": "ARHGAP22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCU6-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein", "gene_name": "PREX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07960-1", "protein_name": "Rho GTPase-activating protein 1", "gene_name": "ARHGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96013-1", "protein_name": "Serine/threonine-protein kinase PAK 4", "gene_name": "PAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3KR16-1", "protein_name": "Pleckstrin homology domain-containing family G member 6", "gene_name": "PLEKHG6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ29-1", "protein_name": "Dedicator of cytokinesis protein 9", "gene_name": "DOCK9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZD9-1", "protein_name": "Dedicator of cytokinesis protein 3", "gene_name": "DOCK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T5U3-1", "protein_name": "Rho GTPase-activating protein 21", "gene_name": "ARHGAP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HP0-1", "protein_name": "Dedicator of cytokinesis protein 6", "gene_name": "DOCK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60763-1", "protein_name": "Ras-related C3 botulinum toxin substrate 3", "gene_name": "RAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19878-1", "protein_name": "Neutrophil cytosol factor 2", "gene_name": "NCF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52566-1", "protein_name": "Rho GDP-dissociation inhibitor 2", "gene_name": "ARHGDIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYF5-1", "protein_name": "Protein FAM13B", "gene_name": "FAM13B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5G2-1", "protein_name": "Macoilin", "gene_name": "MACO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2U8-1", "protein_name": "Inner nuclear membrane protein Man1", "gene_name": "LEMD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13505-1", "protein_name": "Metaxin-1", "gene_name": "MTX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JTV8-1", "protein_name": "Torsin-1A-interacting protein 1", "gene_name": "TOR1AIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86UR1-1", "protein_name": "NADPH oxidase activator 1", "gene_name": "NOXA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RT1-1", "protein_name": "Erbin", "gene_name": "ERBIN", "tax_name": "Human" }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2007", "authors": "Li L, Hisamoto K, Kim KH, Haynes MP, Bauer PM, Sanjay A, Collinge M, Baron R, Sessa WC, Bender JR", "reference": { "type": "PubMed", "id": "17921256", "url": "https://pubmed.ncbi.nlm.nih.gov/17921256" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62873-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "gene_name": "GNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63211-1", "protein_name": "Guanine nucleotide-binding protein G(T) subunit gamma-T1", "gene_name": "GNGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59768-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2", "gene_name": "GNG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60262-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7", "gene_name": "GNG7", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MTJ3-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "GNAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50150-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "gene_name": "GNG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50151-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "gene_name": "GNG10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2W3-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13", "gene_name": "GNG13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05397-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08754-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "gene_name": "GNAI3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63096-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "gene_name": "GNAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09237-1", "protein_name": "Matrilysin", "gene_name": "MMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04792-1", "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29474-1", "protein_name": "Nitric oxide synthase 3", "gene_name": "NOS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63218-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "gene_name": "GNG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99873-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "PRMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16520-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "gene_name": "GNB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04899-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "gene_name": "GNAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14780-1", "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK08-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "gene_name": "GNG8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBI6-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "gene_name": "GNG12", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14775-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-5", "gene_name": "GNB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": "GNG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14610-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2", "gene_name": "GNGT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08254-1", "protein_name": "Stromelysin-1", "gene_name": "MMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17921256", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 55 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q27974-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Bovine" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 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"gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": 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casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17978091", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 129 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.", "journal": "Journal of virology", "date": "2008", "authors": "Lindwasser OW, Smith WJ, Chaudhuri R, Yang P, Hurley JH, Bonifacino JS", "reference": { "type": "PubMed", "id": "18032517", "url": "https://pubmed.ncbi.nlm.nih.gov/18032517" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", 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"protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18039657", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals.", "journal": "Neuron", "date": "2007", "authors": "Mani M, Lee SY, Lucast L, Cremona O, Di Paolo G, De Camilli P, Ryan TA", "reference": { "type": "PubMed", "id": 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{ "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15357-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "gene_name": "INPPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8CHC4-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "Synj1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61106-1", "protein_name": "Ras-related protein Rab-14", "gene_name": "RAB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20338-1", "protein_name": "Ras-related protein Rab-4A", "gene_name": "RAB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB19-1", "protein_name": "Pleckstrin homology domain-containing family A member 2", "gene_name": "PLEKHA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51813-1", "protein_name": "Cytoplasmic tyrosine-protein kinase BMX", "gene_name": "BMX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60484-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "gene_name": "PTEN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13496-1", "protein_name": "Myotubularin", "gene_name": "MTM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13615-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3", "gene_name": "MTMR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12923-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 13", "gene_name": "PTPN13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4M7-1", "protein_name": "Pleckstrin homology domain-containing family A member 4", "gene_name": "PLEKHA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14986-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 beta", "gene_name": "PIP5K1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2H5-1", "protein_name": "Pleckstrin homology domain-containing family A member 6", "gene_name": "PLEKHA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PE3-1", "protein_name": "Inositol polyphosphate-4-phosphatase type I A", "gene_name": "INPP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15327-1", "protein_name": "Inositol polyphosphate 4-phosphatase type II", "gene_name": "INPP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1106, "end_pos": 1107, "sequence_org": "KR", "sequence_mut": "AA", "comment": "Reduces interaction with SH3GL2; when associated with A-1112; A-1119 and A-1125. Does not affect phosphoinosite 5 phoaphatase activity; when associated with A-1112; A-1119 and A-1125. Does not affect Does not affect phosphatidylinositol-3-phosphate phosphatase activity; when associated with A-1112; A-1119 and A-1125. Does not affect phosphatidylinositol-4-phosphate phosphatase; when associated with A-1112; A-1119 and A-1125. Does not affect AMPH interaction; when associated with A-1112; A-1119 and A-1125. Restores the endocytic defect after short stimuli without perturbing the rate ofexocytosis; when associated with A-1112; A-1119 and A-1125. Does not restore the endocytic defect during persistent activity; when associated with A-1112; A-1119 and A-1125. Partially restores vesicle re-availability; when associated with A-1112; A-1119 and A-1125.", "evidence": [ { "database": "UniProtKB", "id": "O43426", "url": "https://www.uniprot.org/uniprotkb/O43426" }, { "database": "PubMed", "id": "18093523", "url": "https://pubmed.ncbi.nlm.nih.gov/18093523" } ], "uniprot_canonical_ac": "O43426-1" }, { "start_pos": 1112, "end_pos": 1112, "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces interaction with SH3GL2; when associated with 1106-AA-1107; A-1119 and A-1125. Does not affect phosphoinosite 5 phoaphatase activity; when associated with 1106-AA-1107; A-1119 and A-1125. Does not affect phosphatidylinositol-3-phosphate phosphatase; when associated with 1106-AA-1107; A-1119 and A-1125. Does not affect phosphatidylinositol-4-phosphate phosphatase; when associated with 1106-AA-1107; A-1119 and A-1125. Does not affect AMPH interaction; when associated with 1106-AA-1107; A-1119 and A-1125. Restores the endocytic defect after short stimuli without perturbing the rate ofexocytosis; when associated with 1106-AA-1107; A-1119 and A-1125. Does not restore the endocytic defect during persistent activity; when associated with 1106-AA-1107; A-1119 and A-1125. Partially restores vesicle re-availability; when associated with 1106-AA-1107; A-1119 and A-1125.", "evidence": [ { "database": "UniProtKB", "id": "O43426", "url": "https://www.uniprot.org/uniprotkb/O43426" }, { "database": "PubMed", "id": "18093523", "url": "https://pubmed.ncbi.nlm.nih.gov/18093523" } ], "uniprot_canonical_ac": "O43426-1" }, { "start_pos": 1119, "end_pos": 1119, "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces interaction with SH3GL2; when associated with 1106-AA-1107; A-1112 and A-1125. Does not affect phosphoinosite 5 phoaphatase activity; when associated with 1106-AA-1107; A-1112 and A-1125. Does not affect phosphatidylinositol-3-phosphate phosphatase; when associated with 1106-AA-1107; A-1112 and A-1125. Does not affect phosphatidylinositol-4-phosphate phosphatase; when associated with 1106-AA-1107; A-1112 and A-1125. Does not affect AMPH interaction; when associated with 1106-AA-1107; A-1112 and A-1125. Restores the endocytic defect after short stimuli without perturbing the rate ofexocytosis; when associated with 1106-AA-1107; A-1112 and A-1125. Does not restore the endocytic defect during persistent activity; when associated with 1106-AA-1107; A-1112 and A-1125. Partially restores vesicle re-availability; when associated with 1106-AA-1107; A-1112 and A-1125.", "evidence": [ { "database": "UniProtKB", "id": "O43426", "url": "https://www.uniprot.org/uniprotkb/O43426" }, { "database": "PubMed", "id": "18093523", "url": "https://pubmed.ncbi.nlm.nih.gov/18093523" } ], "uniprot_canonical_ac": "O43426-1" }, { "start_pos": 1125, "end_pos": 1125, "sequence_org": "R", "sequence_mut": "A", "comment": "Reduces interaction with SH3GL2; when associated with 106-AA-1107; A-1112 and A-1119. Does not affect phosphoinosite 5 phoaphatase activity; when associated with 106-AA-1107; A-1112 and A-1119. Does not affect phosphatidylinositol-3-phosphate phosphatase; when associated with 106-AA-1107; A-1112 and A-1119. Does not affect phosphatidylinositol-4-phosphate phosphatase; when associated with 106-AA-1107; A-1112 and A-1119. Does not affect AMPH interaction; when associated with 106-AA-1107; A-1112 and A-1119. Restores the endocytic defect after short stimuli without perturbing the rate ofexocytosis; when associated with 106-AA-1107; A-1112 and A-1119. Does not restore the endocytic defect during persistent activity; when associated with 106-AA-1107; A-1112 and A-1119. Partially restores vesicle re-availability; when associated with 106-AA-1107; A-1112 and A-1119.", "evidence": [ { "database": "UniProtKB", "id": "O43426", "url": "https://www.uniprot.org/uniprotkb/O43426" }, { "database": "PubMed", "id": "18093523", "url": "https://pubmed.ncbi.nlm.nih.gov/18093523" } ], "uniprot_canonical_ac": "O43426-1" }, { "start_pos": 383, "end_pos": 383, "sequence_org": "C", "sequence_mut": "S", "comment": "Almost complete loss of phosphatidylinositol-3-phosphate phosphatase activity. Almost complete loss of phosphatidylinositol-4-phosphate phosphatase activity. Does not affect the 5-phosphatase activity. Does not affect localization at presynapse. Does not affect exocytosis. Does not restore endocytosis. Does not restore vesicle re-availability.", "evidence": [ { "database": "UniProtKB", "id": "O43426", "url": "https://www.uniprot.org/uniprotkb/O43426" }, { "database": "PubMed", "id": "18093523", "url": "https://pubmed.ncbi.nlm.nih.gov/18093523" } ], "uniprot_canonical_ac": "O43426-1" }, { "start_pos": 730, "end_pos": 730, "sequence_org": "D", "sequence_mut": "A", "comment": "Complete loss of 5-phosphatase activity. Does not affect phosphatidylinositol-3-phosphate phosphatase activity. Does not affect phosphatidylinositol-4-phosphate phosphatase activity. Does not affect presynapse localization. Does not restore vesicle re-availability.", "evidence": [ { "database": "UniProtKB", "id": "O43426", "url": "https://www.uniprot.org/uniprotkb/O43426" }, { "database": "PubMed", "id": "18093523", "url": "https://pubmed.ncbi.nlm.nih.gov/18093523" } ], "uniprot_canonical_ac": "O43426-1" } ], "record_id": "pubmed.18093523", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 176 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2.", "journal": "The Journal of cell biology", "date": "2007", "authors": "Jung N, Wienisch M, Gu M, Rand JB, Muller SL, Krause G, Jorgensen EM, Klingauf J, Haucke V", "reference": { "type": "PubMed", "id": "18166656", "url": "https://pubmed.ncbi.nlm.nih.gov/18166656" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25098-1", "protein_name": "G protein-coupled receptor kinase 2", "gene_name": "GRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS2-1", "protein_name": "COP9 signalosome complex subunit 3", "gene_name": "COPS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14656-1", "protein_name": "Torsin-1A", "gene_name": "TOR1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW8-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "COPS7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99627-1", "protein_name": "COP9 signalosome complex subunit 8", "gene_name": "COPS8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9Q2-1", "protein_name": "COP9 signalosome complex subunit 7b", "gene_name": "COPS7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13098-4", "protein_name": "COP9 signalosome complex subunit 1", "gene_name": "GPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT78-1", "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "COPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15843-1", "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "NEDD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": "Ubiquilin-2", "gene_name": "UBQLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18166656", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.", "journal": "Molecular biology of the cell", "date": "2008", "authors": "N'Diaye EN, Hanyaloglu AC, Kajihara KK, Puthenveedu MA, Wu P, von Zastrow M, Brown EJ", "reference": { "type": "PubMed", "id": "18199683", "url": "https://pubmed.ncbi.nlm.nih.gov/18199683" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25098-1", "protein_name": "G protein-coupled receptor kinase 2", "gene_name": "GRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS2-1", "protein_name": "COP9 signalosome complex subunit 3", "gene_name": "COPS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14656-1", "protein_name": "Torsin-1A", "gene_name": "TOR1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW8-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "COPS7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99627-1", "protein_name": "COP9 signalosome complex subunit 8", "gene_name": "COPS8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9Q2-1", "protein_name": "COP9 signalosome complex subunit 7b", "gene_name": "COPS7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13098-4", "protein_name": "COP9 signalosome complex subunit 1", "gene_name": "GPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT78-1", "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "COPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15843-1", "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "NEDD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": "Ubiquilin-2", "gene_name": "UBQLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18199683", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"https://pubmed.ncbi.nlm.nih.gov/18206197" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62873-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "gene_name": "GNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": 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"uniprot_canonical_ac": "Q99873-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "PRMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16520-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "gene_name": "GNB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04899-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "gene_name": "GNAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14780-1", "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK08-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "gene_name": "GNG8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBI6-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "gene_name": "GNG12", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14775-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-5", "gene_name": "GNB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": "GNG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14610-1", "protein_name": "Guanine nucleotide-binding protein 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"species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18206197", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 55 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells.", "journal": "Oncogene", "date": "2008", "authors": "Horn S, Bergholz U, Jucker M, McCubrey JA, Trumper L, Stocking C, Basecke J", "reference": { "type": "PubMed", "id": "18317450", "url": "https://pubmed.ncbi.nlm.nih.gov/18317450" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15391-1", "protein_name": "B-lymphocyte antigen CD19", "gene_name": "CD19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", 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"Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08581-1", "protein_name": "Hepatocyte growth factor receptor", "gene_name": "MET", "tax_name": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SNX9 regulates tubular invagination of the plasma membrane through interaction with actin cytoskeleton and dynamin 2.", "journal": "Journal of cell science", "date": "2008", "authors": "Shin N, Ahn N, Chang-Ileto B, Park J, Takei K, Ahn SG, Kim SA, Di Paolo G, Chang S", "reference": { "type": "PubMed", "id": "18388313", "url": "https://pubmed.ncbi.nlm.nih.gov/18388313" }, "referenced_glycans": [], 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"uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", 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"protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": 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"uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": 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May not affect insulin signaling and cell proliferation. Partially affects oncogene-induced transformation.", "evidence": [ { "database": "UniProtKB", "id": "P42338", "url": "https://www.uniprot.org/uniprotkb/P42338" }, { "database": "PubMed", "id": "18594509", "url": "https://pubmed.ncbi.nlm.nih.gov/18594509" } ], "uniprot_canonical_ac": "P42338-1" } ], "record_id": "pubmed.18594509", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 74 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of estrogen rapid signaling through arginine methylation by PRMT1.", "journal": "Molecular cell", "date": "2008", "authors": "Le Romancer M, Treilleux I, Leconte N, Robin-Lespinasse Y, Sentis S, Bouchekioua-Bouzaghou K, 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"uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18507-2", "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "GABRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWG1-1", "protein_name": "Pro-neuregulin-4, membrane-bound isoform", "gene_name": "NRG4", "tax_name": "Human" }, { "uniprot_canonical_ac": 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tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1035, "end_pos": 1035, "kinase_uniprot_canonical_ac": "Q15303-1", "kinase_gene_name": "ERBB4", "residue": "Tyr", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "Q15303", "url": 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{ "database": "UniProtKB", "id": "Q15303", "url": "https://www.uniprot.org/uniprotkb/Q15303" }, { "database": "iPTMnet", "id": "Q15303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q15303" }, { "database": "PubMed", "id": "18721752", "url": "https://pubmed.ncbi.nlm.nih.gov/18721752" } ], "site_lbl": "Tyr1242", "uniprot_canonical_ac": "Q15303-1" }, { "start_pos": 1258, "end_pos": 1258, "kinase_uniprot_canonical_ac": "Q15303-1", "kinase_gene_name": "ERBB4", "residue": "Tyr", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "Q15303", "url": "https://www.uniprot.org/uniprotkb/Q15303" }, { "database": "iPTMnet", "id": "Q15303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q15303" }, { "database": "PubMed", "id": "18721752", "url": "https://pubmed.ncbi.nlm.nih.gov/18721752" } ], "site_lbl": "Tyr1258", "uniprot_canonical_ac": "Q15303-1" }, { "start_pos": 1284, "end_pos": 1284, "kinase_uniprot_canonical_ac": "Q15303-1", "kinase_gene_name": "ERBB4", "residue": "Tyr", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "Q15303", "url": "https://www.uniprot.org/uniprotkb/Q15303" }, { "database": "iPTMnet", "id": "Q15303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q15303" }, { "database": "PubMed", "id": "18721752", "url": "https://pubmed.ncbi.nlm.nih.gov/18721752" } ], "site_lbl": "Tyr1284", "uniprot_canonical_ac": "Q15303-1" }, { "start_pos": 875, "end_pos": 875, "kinase_uniprot_canonical_ac": "Q15303-1", "kinase_gene_name": "ERBB4", "residue": "Tyr", "comment": "", "evidence": [ { "database": "UniProtKB", "id": "Q15303", "url": "https://www.uniprot.org/uniprotkb/Q15303" }, { "database": "iPTMnet", "id": "Q15303", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q15303" }, { "database": "PubMed", "id": "18721752", "url": "https://pubmed.ncbi.nlm.nih.gov/18721752" } ], "site_lbl": "Tyr875", "uniprot_canonical_ac": "Q15303-1" } ], "record_id": "pubmed.18721752", "abstract": "", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-t hieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .", "journal": "Journal of medicinal chemistry", "date": "2008", "authors": "Folkes AJ, Ahmadi K, Alderton WK, Alix S, Baker SJ, Box G, Chuckowree IS, Clarke PA, Depledge P, Eccles SA, Friedman LS, Hayes A, Hancox TC, Kugendradas A, Lensun L, Moore P, Olivero AG, Pang J, Patel S, Pergl-Wilson GH, Raynaud FI, Robson A, Saghir N, Salphati L, Sohal S, Ultsch MH, Valenti M, Wallweber HJ, Wan NC, Wiesmann C, Workman P, Zhyvoloup A, Zvelebil MJ, Shuttleworth SJ", "reference": { "type": "PubMed", "id": "18754654", "url": "https://pubmed.ncbi.nlm.nih.gov/18754654" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { 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4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "NRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5UE93-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6", "gene_name": "PIK3R6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16620-1", "protein_name": "BDNF/NT-3 growth factors receptor", "gene_name": "NTRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48736-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUJ8-1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08581-1", "protein_name": "Hepatocyte growth factor receptor", "gene_name": "MET", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42081-1", "protein_name": "T-lymphocyte activation antigen CD86", "gene_name": "CD86", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22455-1", "protein_name": "Fibroblast growth factor receptor 4", "gene_name": "FGFR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWG1-1", "protein_name": "Pro-neuregulin-4, membrane-bound isoform", "gene_name": "NRG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV9-1", "protein_name": "Fibroblast growth factor 23", "gene_name": "FGF23", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP95-1", "protein_name": "Fibroblast growth factor 20", "gene_name": "FGF20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20783-1", "protein_name": "Neurotrophin-3", "gene_name": "NTF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Z14-1", "protein_name": "Beta-klotho", "gene_name": "KLB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10721-1", "protein_name": "Mast/stem cell growth factor receptor Kit", "gene_name": "KIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18754654", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 73 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PTEN-deficient cancers depend on PIK3CB.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Wee S, Wiederschain D, Maira SM, Loo A, Miller C, deBeaumont R, Stegmeier F, Yao YM, Lengauer C", "reference": { "type": "PubMed", "id": "18755892", "url": "https://pubmed.ncbi.nlm.nih.gov/18755892" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15391-1", "protein_name": "B-lymphocyte antigen CD19", "gene_name": "CD19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, 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"protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic 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"gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18755892", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 73 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], 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}, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular basis for the sorting of the SNARE VAMP7 into endocytic clathrin-coated vesicles by the ArfGAP Hrb.", "journal": "Cell", "date": "2008", "authors": "Pryor PR, Jackson L, Gray SR, Edeling MA, Thompson A, Sanderson CM, Evans PR, Owen DJ, Luzio JP", "reference": { "type": "PubMed", "id": "18775314", "url": "https://pubmed.ncbi.nlm.nih.gov/18775314" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 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"protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": 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neurotrauma", "date": "2008", "authors": "Yune TY, Park HG, Lee JY, Oh TH", "reference": { "type": "PubMed", "id": "18785877", "url": "https://pubmed.ncbi.nlm.nih.gov/18785877" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y243-1", "protein_name": "RAC-gamma serine/threonine-protein kinase", "gene_name": "AKT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11831-1", "protein_name": "Serum response factor", "gene_name": "SRF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAS1-1", "protein_name": "Serine/threonine-protein kinase Kist", "gene_name": "UHMK1", 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"P01100-1", "protein_name": "Protein c-Fos", "gene_name": "FOS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18785877", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { 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"tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 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"gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", 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"uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth 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"protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": 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dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9JKY5-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "Hip1r", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18790740", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 129 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role of HRB in clathrin-dependent endocytosis.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Chaineau M, Danglot L, Proux-Gillardeaux V, Galli T", "reference": { "type": "PubMed", "id": "18819912", "url": "https://pubmed.ncbi.nlm.nih.gov/18819912" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25098-1", "protein_name": "G protein-coupled receptor kinase 2", "gene_name": "GRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS2-1", "protein_name": "COP9 signalosome complex subunit 3", "gene_name": "COPS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": 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"Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9Q2-1", "protein_name": "COP9 signalosome complex subunit 7b", "gene_name": "COPS7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13098-4", "protein_name": "COP9 signalosome complex subunit 1", "gene_name": "GPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT78-1", "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "COPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15843-1", "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "NEDD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": "Ubiquilin-2", "gene_name": "UBQLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18819912", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.", "journal": "Cancer research", "date": "2008", "authors": "Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, Botero ML, Llonch E, Atzori F, Di Cosimo S, Maira M, Garcia-Echeverria C, Parra JL, Arribas J, Baselga J", "reference": { "type": "PubMed", "id": "18829560", "url": "https://pubmed.ncbi.nlm.nih.gov/18829560" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15391-1", "protein_name": "B-lymphocyte antigen CD19", "gene_name": "CD19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "NRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5UE93-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6", "gene_name": "PIK3R6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16620-1", "protein_name": "BDNF/NT-3 growth factors receptor", "gene_name": "NTRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48736-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUJ8-1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", 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}, { "title": "Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells.", "journal": "The Journal of cell biology", "date": "2008", "authors": "Zaoui K, Honore S, Isnardon D, Braguer D, Badache A", "reference": { "type": "PubMed", "id": "18955552", "url": "https://pubmed.ncbi.nlm.nih.gov/18955552" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61586-1", "protein_name": "Transforming protein RhoA", "gene_name": "RHOA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", 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"uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18981233", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2009", "authors": "Kazazic M, Bertelsen V, Pedersen KW, Vuong TT, Grandal MV, Rodland MS, Traub LM, Stang E, Madshus IH", "reference": { "type": "PubMed", "id": "19054389", "url": "https://pubmed.ncbi.nlm.nih.gov/19054389" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 12", "gene_name": "PTPN12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60953-2", "protein_name": "Cell division control protein 42 homolog", "gene_name": "CDC42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14155-4", "protein_name": "Rho guanine nucleotide exchange factor 7", "gene_name": "ARHGEF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43609-1", "protein_name": "Protein sprouty homolog 1", "gene_name": "SPRY1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15262-1", "protein_name": "Receptor-type tyrosine-protein phosphatase kappa", "gene_name": "PTPRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43597-1", "protein_name": "Protein sprouty homolog 2", "gene_name": "SPRY2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26045-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 3", "gene_name": "PTPN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19054389", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SNX9 - a prelude to vesicle release.", "journal": "Journal of cell science", "date": "2009", "authors": "Lundmark R, Carlsson SR", "reference": { "type": "PubMed", "id": "19092055", "url": "https://pubmed.ncbi.nlm.nih.gov/19092055" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { 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"protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated 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"protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19092055", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells.", "journal": "Steroids", "date": "2009", "authors": "Santen RJ, Fan P, Zhang Z, Bao Y, Song RX, Yue W", "reference": { "type": "PubMed", "id": "19138696", "url": "https://pubmed.ncbi.nlm.nih.gov/19138696" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62873-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "gene_name": "GNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63211-1", "protein_name": "Guanine nucleotide-binding protein G(T) subunit gamma-T1", "gene_name": "GNGT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59768-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2", "gene_name": "GNG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60262-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7", "gene_name": "GNG7", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MTJ3-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "GNAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50150-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "gene_name": "GNG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50151-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "gene_name": "GNG10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2W3-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13", "gene_name": "GNG13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05397-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08754-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "gene_name": "GNAI3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63096-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "gene_name": "GNAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09237-1", "protein_name": "Matrilysin", "gene_name": "MMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04792-1", "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29474-1", "protein_name": "Nitric oxide synthase 3", "gene_name": "NOS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63218-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "gene_name": "GNG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99873-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "PRMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16520-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "gene_name": "GNB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04899-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "gene_name": "GNAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14780-1", "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK08-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "gene_name": "GNG8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBI6-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "gene_name": "GNG12", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14775-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-5", "gene_name": "GNB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": "GNG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14610-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2", "gene_name": "GNGT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08254-1", "protein_name": "Stromelysin-1", "gene_name": "MMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19138696", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 55 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex.", "journal": "Nature", "date": "2008", "authors": "Kelly BT, McCoy AJ, Spate K, Miller SE, Evans PR, Honing S, Owen DJ", "reference": { "type": "PubMed", "id": "19140243", "url": "https://pubmed.ncbi.nlm.nih.gov/19140243" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25098-1", "protein_name": "G protein-coupled receptor kinase 2", "gene_name": "GRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNS2-1", "protein_name": "COP9 signalosome complex subunit 3", "gene_name": "COPS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17427-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "Ap2a2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14656-1", "protein_name": "Torsin-1A", "gene_name": "TOR1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW8-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "COPS7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99627-1", "protein_name": "COP9 signalosome complex subunit 8", "gene_name": "COPS8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": 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"protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", 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"uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08581-1", "protein_name": "Hepatocyte growth factor receptor", "gene_name": "MET", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42081-1", "protein_name": "T-lymphocyte activation antigen CD86", "gene_name": "CD86", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22455-1", "protein_name": "Fibroblast growth factor receptor 4", "gene_name": "FGFR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWG1-1", "protein_name": "Pro-neuregulin-4, membrane-bound isoform", "gene_name": "NRG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV9-1", "protein_name": 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"protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10721-1", "protein_name": "Mast/stem cell growth factor receptor Kit", "gene_name": "KIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy.", "journal": "Cancer research", "date": "2009", "authors": "Indraccolo S, Minuzzo S, Masiero M, Pusceddu I, Persano L, Moserle L, Reboldi A, Favaro E, Mecarozzi M, Di Mario G, Screpanti I, Ponzoni M, Doglioni C, Amadori A", "reference": { "type": "PubMed", "id": "19208840", "url": "https://pubmed.ncbi.nlm.nih.gov/19208840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00308-1", "protein_name": "NEDD4-like E3 ubiquitin-protein ligase WWP2", "gene_name": "WWP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92542-1", "protein_name": "Nicastrin", "gene_name": "NCSTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BI3-1", "protein_name": "Gamma-secretase subunit APH-1A", "gene_name": "APH1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A5-1", "protein_name": "Transforming acidic coiled-coil-containing protein 3", "gene_name": "TACC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR61-1", "protein_name": "Delta-like protein 4", "gene_name": "DLL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ42-1", "protein_name": "Gamma-secretase subunit PEN-2", "gene_name": "PSENEN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM47-1", "protein_name": "Neurogenic locus notch homolog protein 3", "gene_name": "NOTCH3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MQ27-1", "protein_name": "E3 ubiquitin-protein ligase NEURL1B", "gene_name": "NEURL1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78504-1", "protein_name": "Protein jagged-1", "gene_name": "JAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76050-1", "protein_name": 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"Human" }, { "uniprot_canonical_ac": "Q9Y219-1", "protein_name": "Protein jagged-2", "gene_name": "JAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49768-1", "protein_name": "Presenilin-1", "gene_name": "PSEN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14672-1", "protein_name": "Disintegrin and metalloproteinase domain-containing protein 10", "gene_name": "ADAM10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19208840", "abstract": "", "glycosylation": [], 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"url": "https://pubmed.ncbi.nlm.nih.gov/19287005" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { 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"gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62944-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "Ap2b1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O70161-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "Pip5k1c", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 756, "end_pos": 756, "sequence_org": "Q", "sequence_mut": "A", "comment": "Abolishes interaction with PIP5K1C.", "evidence": [ { "database": "UniProtKB", "id": "P62944", "url": "https://www.uniprot.org/uniprotkb/P62944" }, { "database": "PubMed", "id": "19287005", "url": "https://pubmed.ncbi.nlm.nih.gov/19287005" } ], "uniprot_canonical_ac": "P62944-1" }, { "start_pos": 804, "end_pos": 804, "sequence_org": "Q", "sequence_mut": "A", "comment": "Abolishes interaction with PIP5K1C.", "evidence": [ { "database": "UniProtKB", "id": "P62944", "url": "https://www.uniprot.org/uniprotkb/P62944" }, { "database": "PubMed", "id": "19287005", "url": "https://pubmed.ncbi.nlm.nih.gov/19287005" } ], "uniprot_canonical_ac": "P62944-1" }, { "start_pos": 806, "end_pos": 806, "sequence_org": "A", "sequence_mut": "F", "comment": "Abolishes interaction with PIP5K1C.", "evidence": [ { "database": "UniProtKB", "id": "P62944", "url": "https://www.uniprot.org/uniprotkb/P62944" }, { "database": "PubMed", "id": "19287005", "url": "https://pubmed.ncbi.nlm.nih.gov/19287005" } ], "uniprot_canonical_ac": "P62944-1" }, { "start_pos": 808, "end_pos": 808, "sequence_org": "K", "sequence_mut": "E", "comment": "Abolishes interaction with PIP5K1C.", "evidence": [ { "database": "UniProtKB", "id": "P62944", "url": "https://www.uniprot.org/uniprotkb/P62944" }, { "database": "PubMed", "id": "19287005", "url": "https://pubmed.ncbi.nlm.nih.gov/19287005" } ], "uniprot_canonical_ac": "P62944-1" }, { "start_pos": 815, "end_pos": 815, "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with PIP5K1C.", "evidence": [ { "database": "UniProtKB", "id": "P62944", "url": "https://www.uniprot.org/uniprotkb/P62944" }, { "database": "PubMed", "id": "19287005", "url": "https://pubmed.ncbi.nlm.nih.gov/19287005" } ], "uniprot_canonical_ac": "P62944-1" }, { "start_pos": 635, "end_pos": 635, "sequence_org": "F", "sequence_mut": "A", "comment": "Abolishes interaction with AP2B1.", "evidence": [ { "database": "UniProtKB", "id": "O70161", "url": 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"name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19296720", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941.", "journal": "Cancer cell", "date": "2009", "authors": "Junttila TT, Akita RW, Parsons K, Fields C, Lewis Phillips GD, Friedman LS, Sampath D, Sliwkowski MX", "reference": { "type": "PubMed", "id": "19411071", "url": "https://pubmed.ncbi.nlm.nih.gov/19411071" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": 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"uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "NRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5UE93-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6", "gene_name": "PIK3R6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16620-1", "protein_name": "BDNF/NT-3 growth factors receptor", "gene_name": "NTRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48736-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUJ8-1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19411071", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits.", "journal": "Molecular biology of the cell", "date": "2009", "authors": "Mettlen M, Stoeber M, Loerke D, Antonescu CN, Danuser G, Schmid SL", "reference": { "type": "PubMed", "id": "19458185", "url": "https://pubmed.ncbi.nlm.nih.gov/19458185" }, 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"uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", 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"uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism.", "journal": "The EMBO journal", "date": "2009", "authors": "Mao Y, Balkin DM, Zoncu R, Erdmann KS, Tomasini L, Hu F, Jin MM, Hodsdon ME, De Camilli P", "reference": { "type": "PubMed", "id": "19536138", "url": "https://pubmed.ncbi.nlm.nih.gov/19536138" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": 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"uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", 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"Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { 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"protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8K337-1", "protein_name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "gene_name": "Inpp5b", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", 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growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19575674", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PtdIns5P protects Akt from dephosphorylation through PP2A inhibition.", "journal": "Biochemical and biophysical research communications", "date": "2009", "authors": "Ramel D, Lagarrigue F, Dupuis-Coronas S, Chicanne G, Leslie N, Gaits-Iacovoni F, Payrastre B, Tronchere H", "reference": { "type": "PubMed", "id": "19576174", "url": "https://pubmed.ncbi.nlm.nih.gov/19576174" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06213-1", "protein_name": "Insulin receptor", "gene_name": "INSR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01638-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "IL1RL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15391-1", "protein_name": "B-lymphocyte antigen CD19", "gene_name": "CD19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWZ3-1", "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78356-1", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 beta", "gene_name": "PIP4K2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "NRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5UE93-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6", "gene_name": "PIK3R6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16620-1", "protein_name": "BDNF/NT-3 growth factors receptor", "gene_name": "NTRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48736-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBX8-1", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "gene_name": "PIP4K2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUJ8-1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99755-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "gene_name": "PIP5K1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48426-1", "protein_name": "Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha", "gene_name": "PIP4K2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14986-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 beta", "gene_name": "PIP5K1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08581-1", "protein_name": "Hepatocyte growth factor receptor", "gene_name": "MET", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42081-1", "protein_name": "T-lymphocyte activation antigen CD86", "gene_name": "CD86", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22455-1", "protein_name": "Fibroblast growth factor receptor 4", "gene_name": "FGFR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWG1-1", "protein_name": "Pro-neuregulin-4, membrane-bound isoform", "gene_name": "NRG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV9-1", "protein_name": "Fibroblast growth factor 23", "gene_name": "FGF23", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP95-1", "protein_name": "Fibroblast growth factor 20", "gene_name": "FGF20", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01308-1", "protein_name": "Insulin", "gene_name": "INS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95760-1", "protein_name": "Interleukin-33", "gene_name": "IL33", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20783-1", "protein_name": "Neurotrophin-3", "gene_name": "NTF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Z14-1", "protein_name": "Beta-klotho", "gene_name": "KLB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10721-1", "protein_name": "Mast/stem cell growth factor receptor Kit", "gene_name": "KIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46695-1", "protein_name": "Radiation-inducible immediate-early gene IEX-1", "gene_name": "IER3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14738-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "gene_name": "PPP2R5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19576174", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 100 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Molecular cell biology", "date": "2009", "authors": "Stenmark H", "reference": { "type": "PubMed", "id": "19603039", "url": "https://pubmed.ncbi.nlm.nih.gov/19603039" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AH8-1", "protein_name": "Ras-related protein Rab-7b", "gene_name": "RAB7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXH6-1", "protein_name": "Ras-related protein Rab-40A", "gene_name": "RAB40A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRW1-1", "protein_name": "Ras-related protein Rab-6B", "gene_name": "RAB6B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14088-1", "protein_name": "Ras-related protein Rab-33A", "gene_name": "RAB33A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULW5-1", "protein_name": "Ras-related protein Rab-26", "gene_name": "RAB26", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53611-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RABGGTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0T7-1", "protein_name": "Ras-related protein Rab-17", "gene_name": "RAB17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20340-1", "protein_name": "Ras-related protein Rab-6A", "gene_name": "RAB6A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N4Z0-2", "protein_name": "Ras-related protein Rab-42", "gene_name": "RAB42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DA2-1", "protein_name": "Ras-related protein Rab-39B", "gene_name": "RAB39B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YS6-1", "protein_name": "Ras-related protein Rab-43", "gene_name": "RAB43", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51159-1", "protein_name": "Ras-related protein Rab-27A", "gene_name": "RAB27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62491-1", "protein_name": "Ras-related protein Rab-11A", "gene_name": "RAB11A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00194-1", "protein_name": "Ras-related protein Rab-27B", "gene_name": "RAB27B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62821-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "Rab1a", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92696-1", "protein_name": "Geranylgeranyl transferase type-2 subunit alpha", "gene_name": "RABGGTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59190-1", "protein_name": "Ras-related protein Rab-15", "gene_name": "RAB15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15771-1", "protein_name": "Ras-related protein Rab-30", "gene_name": "RAB30", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13636-1", "protein_name": "Ras-related protein Rab-31", "gene_name": "RAB31", "tax_name": "Human" }, { "uniprot_canonical_ac": "A4D1S5-1", "protein_name": "Ras-related protein Rab-19", "gene_name": "RAB19", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95755-1", "protein_name": "Ras-related protein Rab-36", "gene_name": "RAB36", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57735-1", "protein_name": "Ras-related protein Rab-25", "gene_name": "RAB25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E17-1", "protein_name": "Ras-related protein Rab-3C", "gene_name": "RAB3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC3-1", "protein_name": "Ras-related protein Rab-23", "gene_name": "RAB23", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969Q5-1", "protein_name": "Ras-related protein Rab-24", "gene_name": "RAB24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z6P3-1", "protein_name": "Ras-related protein Rab-44", "gene_name": "RAB44", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57729-1", "protein_name": "Ras-related protein Rab-38", "gene_name": "RAB38", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92930-1", "protein_name": "Ras-related protein Rab-8B", "gene_name": "RAB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95716-1", "protein_name": "Ras-related protein Rab-3D", "gene_name": "RAB3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20337-1", "protein_name": "Ras-related protein Rab-3B", "gene_name": "RAB3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX57-1", "protein_name": "Ras-related protein Rab-20", "gene_name": "RAB20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UL25-1", "protein_name": "Ras-related protein Rab-21", "gene_name": "RAB21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13637-1", "protein_name": "Ras-related protein Rab-32", "gene_name": "RAB32", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51151-1", "protein_name": "Ras-related protein Rab-9A", "gene_name": "RAB9A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61006-1", "protein_name": "Ras-related protein Rab-8A", "gene_name": "RAB8A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61026-1", "protein_name": "Ras-related protein Rab-10", "gene_name": "RAB10", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14966-1", "protein_name": "Ras-related protein Rab-29", "gene_name": "RAB29", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IQ22-1", "protein_name": "Ras-related protein Rab-12", "gene_name": "RAB12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U4-1", "protein_name": "Ras-related protein Rab-1B", "gene_name": "RAB1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51153-1", "protein_name": "Ras-related protein Rab-13", "gene_name": "RAB13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61106-1", "protein_name": "Ras-related protein Rab-14", "gene_name": "RAB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61018-1", "protein_name": "Ras-related protein Rab-4B", "gene_name": "RAB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20338-1", "protein_name": "Ras-related protein Rab-4A", "gene_name": "RAB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62820-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "RAB1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14964-1", "protein_name": "Ras-related protein Rab-39A", "gene_name": "RAB39A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUD1-1", "protein_name": "Ras-related protein Rab-2B", "gene_name": "RAB2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZG1-1", "protein_name": "Ras-related protein Rab-34", "gene_name": "RAB34", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15907-1", "protein_name": "Ras-related protein Rab-11B", "gene_name": "RAB11B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12829-1", "protein_name": "Ras-related protein Rab-40B", "gene_name": "RAB40B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26374-1", "protein_name": "Rab proteins geranylgeranyltransferase component A 2", "gene_name": "CHML", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24386-1", "protein_name": "Rab proteins geranylgeranyltransferase component A 1", "gene_name": "CHM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H082-1", "protein_name": "Ras-related protein Rab-33B", "gene_name": "RAB33B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51149-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "RAB7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5JT25-1", "protein_name": "Ras-related protein Rab-41", "gene_name": "RAB41", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP72-1", "protein_name": "Ras-related protein Rab-18", "gene_name": "RAB18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96S21-1", "protein_name": "Ras-related protein Rab-40C", "gene_name": "RAB40C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP90-1", "protein_name": "Ras-related protein Rab-9B", "gene_name": "RAB9B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12974-1", "protein_name": "Protein tyrosine phosphatase type IVA 2", "gene_name": "PTP4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UL26-1", "protein_name": "Ras-related protein Rab-22A", "gene_name": "RAB22A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61019-1", "protein_name": "Ras-related protein Rab-2A", "gene_name": "RAB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20336-1", "protein_name": "Ras-related protein Rab-3A", "gene_name": "RAB3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15286-1", "protein_name": "Ras-related protein Rab-35", "gene_name": "RAB35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX2-1", "protein_name": "Ras-related protein Rab-37", "gene_name": "RAB37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": 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"Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19603039", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 191 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Targeting the phosphoinositide 3-kinase pathway in cancer.", "journal": "Nature reviews. Drug discovery", "date": "2009", "authors": "Liu P, Cheng H, Roberts TM, Zhao JJ", "reference": { "type": "PubMed", "id": "19644473", "url": "https://pubmed.ncbi.nlm.nih.gov/19644473" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y243-1", "protein_name": "RAC-gamma serine/threonine-protein kinase", "gene_name": "AKT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12778-1", "protein_name": "Forkhead box protein O1", "gene_name": "FOXO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B 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"P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08581-1", "protein_name": "Hepatocyte growth factor receptor", "gene_name": "MET", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38936-1", "protein_name": "Cyclin-dependent kinase inhibitor 1", "gene_name": "CDKN1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42081-1", "protein_name": "T-lymphocyte activation antigen CD86", "gene_name": "CD86", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22455-1", "protein_name": "Fibroblast growth factor 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"Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10721-1", "protein_name": "Mast/stem cell growth factor receptor Kit", "gene_name": "KIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49815-1", "protein_name": "Tuberin", "gene_name": "TSC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00987-1", "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15530-1", "protein_name": "3-phosphoinositide-dependent protein kinase 1", "gene_name": "PDPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B36-1", "protein_name": "Proline-rich AKT1 substrate 1", "gene_name": "AKT1S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19644473", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 98 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.", "journal": "The Journal of biological chemistry", "date": "1990", "authors": "Chen WJ, Goldstein JL, 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"protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": 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"gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1968060", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tickets to ride: selecting cargo for clathrin-regulated internalization.", "journal": "Nature reviews. Molecular cell biology", "date": "2009", "authors": "Traub LM", "reference": { "type": "PubMed", "id": "19696796", "url": "https://pubmed.ncbi.nlm.nih.gov/19696796" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": 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}, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": 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"uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing 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"uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19696796", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Endocytosis and signalling: intertwining molecular networks.", "journal": "Nature reviews. Molecular cell biology", "date": "2009", "authors": "Sorkin A, von Zastrow M", "reference": { "type": "PubMed", "id": "19696798", "url": "https://pubmed.ncbi.nlm.nih.gov/19696798" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": 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"uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19696798", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Syp1 is a conserved endocytic adaptor that contains domains involved in cargo selection and membrane tubulation.", "journal": "The EMBO journal", "date": "2009", "authors": "Reider A, Barker SL, Mishra SK, Im YJ, Maldonado-Baez L, Hurley JH, Traub LM, Wendland B", "reference": { "type": "PubMed", "id": "19713939", "url": "https://pubmed.ncbi.nlm.nih.gov/19713939" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex 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chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", 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"protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19732400", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Early-arriving Syp1p and Ede1p function in endocytic site placement and formation in budding yeast.", "journal": "Molecular biology of the cell", "date": "2009", "authors": "Stimpson HE, Toret CP, Cheng AT, Pauly BS, Drubin DG", "reference": { "type": "PubMed", "id": "19776351", "url": "https://pubmed.ncbi.nlm.nih.gov/19776351" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 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"uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": 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"Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25623-1", "protein_name": "Suppressor of yeast profilin deletion", "gene_name": "SYP1", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P34216-1", "protein_name": "EH domain-containing and endocytosis protein 1", "gene_name": "EDE1", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19776351", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 130 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2009", "authors": "Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM", "reference": { "type": "PubMed", "id": "19805105", "url": "https://pubmed.ncbi.nlm.nih.gov/19805105" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00141-1", "protein_name": "Serine/threonine-protein kinase Sgk1", "gene_name": "SGK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIZ9-1", "protein_name": "T-cell receptor-associated transmembrane adapter 1", "gene_name": "TRAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34130-1", "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y243-1", "protein_name": "RAC-gamma serine/threonine-protein kinase", "gene_name": "AKT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T1C6-1", "protein_name": "Acyl-coenzyme A thioesterase THEM4", "gene_name": "THEM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU7-1", "protein_name": "Tribbles homolog 3", "gene_name": "TRIB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56975-1", "protein_name": "Pro-neuregulin-3, membrane-bound isoform", "gene_name": "NRG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01638-1", "protein_name": "Interleukin-1 receptor-like 1", "gene_name": "IL1RL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15391-1", "protein_name": "B-lymphocyte antigen CD19", "gene_name": "CD19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92731-1", "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": 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"gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": 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mTOR", "gene_name": "MTOR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31751-1", "protein_name": "RAC-beta serine/threonine-protein kinase", "gene_name": "AKT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76093-1", "protein_name": "Fibroblast growth factor 18", "gene_name": "FGF18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEB9-1", "protein_name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "gene_name": "PIK3C3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46527-1", "protein_name": "Cyclin-dependent kinase inhibitor 1B", "gene_name": "CDKN1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14210-1", "protein_name": "Hepatocyte growth factor", "gene_name": "HGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23560-1", "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15153-1", "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16288-1", "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04629-1", "protein_name": "High affinity nerve growth factor receptor", "gene_name": "NTRK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08581-1", "protein_name": "Hepatocyte growth factor receptor", "gene_name": "MET", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42081-1", "protein_name": "T-lymphocyte activation antigen CD86", "gene_name": "CD86", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22455-1", "protein_name": "Fibroblast growth factor receptor 4", "gene_name": "FGFR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWG1-1", "protein_name": "Pro-neuregulin-4, membrane-bound isoform", "gene_name": "NRG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV9-1", "protein_name": "Fibroblast growth factor 23", "gene_name": "FGF23", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP95-1", "protein_name": "Fibroblast growth factor 20", "gene_name": "FGF20", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95760-1", "protein_name": "Interleukin-33", "gene_name": "IL33", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20783-1", "protein_name": "Neurotrophin-3", "gene_name": "NTF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13322-1", "protein_name": "Growth factor receptor-bound protein 10", "gene_name": "GRB10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Z14-1", "protein_name": "Beta-klotho", "gene_name": "KLB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10721-1", "protein_name": "Mast/stem cell growth factor receptor Kit", "gene_name": "KIT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15530-1", "protein_name": "3-phosphoinositide-dependent protein kinase 1", "gene_name": "PDPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19805105", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 105 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Distinct dynamics of endocytic clathrin-coated pits and coated plaques.", "journal": "PLoS biology", "date": "2009", "authors": "Saffarian S, Cocucci E, Kirchhausen T", "reference": { "type": "PubMed", "id": "19809571", "url": "https://pubmed.ncbi.nlm.nih.gov/19809571" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate 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"uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": 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"uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": 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"uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": 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"O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19809571", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"Human" }, { "uniprot_canonical_ac": "P63096-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "gene_name": "GNAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09237-1", "protein_name": "Matrilysin", "gene_name": "MMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04792-1", "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29474-1", "protein_name": "Nitric oxide synthase 3", "gene_name": "NOS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63218-1", "protein_name": 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"uniprot_canonical_ac": "P14780-1", "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK08-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "gene_name": "GNG8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBI6-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "gene_name": "GNG12", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14775-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-5", "gene_name": "GNB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": 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"uniprot_canonical_ac": "P60985-1", "protein_name": "Keratinocyte differentiation-associated protein", "gene_name": "KRTDAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35326-1", "protein_name": "Small proline-rich protein 2A", "gene_name": "SPRR2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ38-1", "protein_name": "Serine protease inhibitor Kazal-type 5", "gene_name": "SPINK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P47929-1", "protein_name": "Galectin-7", "gene_name": "LGALS7B; LGALS7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35030-1", "protein_name": "Trypsin-3", "gene_name": "PRSS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00548-1", "protein_name": "Delta-like protein 1", "gene_name": "DLL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01469-1", "protein_name": "Fatty acid-binding protein 5", "gene_name": "FABP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08727-1", "protein_name": "Keratin, type I cytoskeletal 19", 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"uniprot_canonical_ac": "P48736-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUJ8-1", "protein_name": "Phosphoinositide 3-kinase adapter protein 1", "gene_name": "PIK3AP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84095-1", "protein_name": "Rho-related GTP-binding protein RhoG", "gene_name": "RHOG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": "FGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYR1-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10767-1", "protein_name": "Fibroblast growth factor 6", "gene_name": "FGF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43320-1", "protein_name": "Fibroblast growth factor 16", "gene_name": "FGF16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95750-1", "protein_name": "Fibroblast growth factor 19", "gene_name": "FGF19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08620-1", "protein_name": "Fibroblast growth factor 4", "gene_name": "FGF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11487-1", "protein_name": "Fibroblast growth factor 3", "gene_name": "FGF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21781-1", "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", 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[] } ] }, { "title": "Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.", "journal": "Nature", "date": "2009", "authors": "Zhou W, Ercan D, Chen L, Yun CH, Li D, Capelletti M, Cortot AB, Chirieac L, Iacob RE, Padera R, Engen JR, Wong KK, Eck MJ, Gray NS, Janne PA", "reference": { "type": "PubMed", "id": "20033049", "url": "https://pubmed.ncbi.nlm.nih.gov/20033049" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04973-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Bovine" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20033059", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 133 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"Developmental cell", "date": "2009", "authors": "Ferguson SM, Raimondi A, Paradise S, Shen H, Mesaki K, Ferguson A, Destaing O, Ko G, Takasaki J, Cremona O, O' Toole E, De Camilli P", "reference": { "type": "PubMed", "id": "20059951", "url": "https://pubmed.ncbi.nlm.nih.gov/20059951" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": 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"protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": 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"uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20059951", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14656-1", "protein_name": "Torsin-1A", "gene_name": "TOR1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBW8-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "COPS7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99627-1", "protein_name": "COP9 signalosome complex subunit 8", "gene_name": "COPS8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit 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"Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61201-1", "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "COPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC2-1", "protein_name": "Epidermal growth factor receptor substrate 15-like 1", "gene_name": "EPS15L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98082-1", "protein_name": "Disabled homolog 2", "gene_name": "DAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43493-2", "protein_name": "Trans-Golgi network integral membrane protein 2", "gene_name": "TGOLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75379-1", "protein_name": "Vesicle-associated membrane protein 4", "gene_name": "VAMP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI5-1", "protein_name": "SH3-containing GRB2-like protein 3-interacting protein 1", "gene_name": "SGIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16572-1", "protein_name": "Vesicular acetylcholine transporter", "gene_name": "SLC18A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9Q2-1", "protein_name": "COP9 signalosome complex subunit 7b", "gene_name": "COPS7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13098-4", "protein_name": "COP9 signalosome complex subunit 1", "gene_name": "GPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT78-1", "protein_name": "COP9 signalosome complex subunit 4", "gene_name": "COPS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15843-1", "protein_name": "Ubiquitin-like protein NEDD8", "gene_name": "NEDD8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZM3-1", "protein_name": "Intersectin-2", "gene_name": "ITSN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98164-1", "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNF0-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 2", "gene_name": "PACSIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99961-1", "protein_name": "Endophilin-A2", "gene_name": "SH3GL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08081-1", "protein_name": "Clathrin light chain A", "gene_name": "Clta", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P30556-1", "protein_name": "Type-1 angiotensin II receptor", "gene_name": "AGTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00610-1", "protein_name": "Clathrin heavy chain 1", "gene_name": "CLTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07550-1", "protein_name": "Beta-2 adrenergic receptor", "gene_name": "ADRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD9-1", "protein_name": "Ubiquilin-2", "gene_name": "UBQLN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11142-1", "protein_name": "Heat shock cognate 71 kDa protein", "gene_name": "HSPA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96B97-1", "protein_name": "SH3 domain-containing kinase-binding protein 1", "gene_name": "SH3KBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63010-1", "protein_name": "AP-2 complex subunit beta", "gene_name": "AP2B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32121-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63261-1", "protein_name": "Actin, cytoplasmic 2", "gene_name": "ACTG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50570-1", "protein_name": "Dynamin-2", "gene_name": "DNM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49407-1", "protein_name": "Beta-arrestin-1", "gene_name": "ARRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L5N1-1", "protein_name": "COP9 signalosome complex subunit 6", "gene_name": "COPS6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35626-1", "protein_name": "G protein-coupled receptor kinase 3", "gene_name": "GRK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92747-1", "protein_name": "Actin-related protein 2/3 complex subunit 1A", "gene_name": "ARPC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62330-1", "protein_name": "ADP-ribosylation factor 6", "gene_name": "ARF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SW96-1", "protein_name": "Low density lipoprotein receptor adapter protein 1", "gene_name": "LDLRAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01130-1", "protein_name": "Low-density lipoprotein receptor", "gene_name": "LDLR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CW1-1", "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49418-1", "protein_name": "Amphiphysin", "gene_name": "AMPH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02786-1", "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01968-1", "protein_name": "Inositol polyphosphate 5-phosphatase OCRL", "gene_name": "OCRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV1-1", "protein_name": "Frizzled-4", "gene_name": "FZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14C86-1", "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1", "gene_name": "GAPVD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92905-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "COPS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14657-1", "protein_name": "Torsin-1B", "gene_name": "TOR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05193-1", "protein_name": "Dynamin-1", "gene_name": "DNM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6I3-2", "protein_name": "Epsin-1", "gene_name": "EPN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51148-1", "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0JRZ9-1", "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ16-1", "protein_name": "Dynamin-3", "gene_name": "DNM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42566-1", "protein_name": "Epidermal growth factor receptor substrate 15", "gene_name": "EPS15", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95208-1", "protein_name": "Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20231386", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 145 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"Epsin-2", "gene_name": "EPN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXE9-1", "protein_name": "Stonin-2", "gene_name": "STON2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11717-1", "protein_name": "Cation-independent mannose-6-phosphate receptor", "gene_name": "IGF2R", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20645-1", "protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMX0-1", "protein_name": "Ubiquilin-1", "gene_name": "UBQLN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20351096", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 104 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "G domain dimerization controls dynamin's assembly-stimulated GTPase activity.", "journal": "Nature", "date": "2010", "authors": "Chappie JS, Acharya S, Leonard M, Schmid SL, Dyda F", "reference": { "type": "PubMed", "id": "20428113", "url": "https://pubmed.ncbi.nlm.nih.gov/20428113" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": 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"uniprot_canonical_ac": "O15056-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2", "gene_name": "SYNJ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41221-1", "protein_name": "Protein Wnt-5a", "gene_name": "WNT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09496-1", "protein_name": "Clathrin light chain A", "gene_name": "CLTA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14108-1", "protein_name": "Lysosome membrane protein 2", "gene_name": "SCARB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60331-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "gene_name": "PIP5K1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY11-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 1", "gene_name": "PACSIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": 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"protein_name": "Cation-dependent mannose-6-phosphate receptor", "gene_name": "M6PR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVZ3-1", "protein_name": "Adaptin ear-binding coat-associated protein 2", "gene_name": "NECAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC96-1", "protein_name": "Adaptin ear-binding coat-associated protein 1", "gene_name": "NECAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKS6-1", "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3", "gene_name": "PACSIN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08172-1", "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60709-1", "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99962-1", "protein_name": "Endophilin-A1", "gene_name": "SH3GL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 180, "end_pos": 180, "sequence_org": "D", "sequence_mut": "A", "comment": "Inhibits assembly-stimulated GTPase activity. Significantly increases basal GTPase activity Does not affect membrane binding. Does not affect self-assembly.", "evidence": [ { "database": "UniProtKB", "id": "Q05193", "url": "https://www.uniprot.org/uniprotkb/Q05193" }, { "database": "PubMed", "id": "20428113", "url": "https://pubmed.ncbi.nlm.nih.gov/20428113" } ], "uniprot_canonical_ac": "Q05193-1" }, { "start_pos": 40, "end_pos": 40, "sequence_org": "Q", "sequence_mut": "E", "comment": "Impairs assembly-stimulated GTPase activity. Does not affect basal GTPase activity. Does not affect membrane binding. Does not affect self-assembly. Completely inhibits receptor internalization.", "evidence": [ { "database": "UniProtKB", "id": "Q05193", "url": "https://www.uniprot.org/uniprotkb/Q05193" }, { "database": "PubMed", "id": "20428113", "url": "https://pubmed.ncbi.nlm.nih.gov/20428113" } ], "uniprot_canonical_ac": "Q05193-1" }, { "start_pos": 41, "end_pos": 41, "sequence_org": "S", "sequence_mut": "A", "comment": "Impairs assembly-stimulated GTPase activity. Does not affect basal GTPase activity. Does not affect membrane binding. Does not affect self-assembly.", "evidence": [ { "database": "UniProtKB", "id": "Q05193", "url": "https://www.uniprot.org/uniprotkb/Q05193" }, { "database": "PubMed", "id": "20428113", "url": "https://pubmed.ncbi.nlm.nih.gov/20428113" } ], "uniprot_canonical_ac": "Q05193-1" } ], "record_id": "pubmed.20428113", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 128 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Razandi M, Pedram A, Levin ER", "reference": { "type": "PubMed", "id": "20439495", "url": "https://pubmed.ncbi.nlm.nih.gov/20439495" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 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"protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08754-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "gene_name": "GNAI3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63096-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "gene_name": "GNAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09237-1", "protein_name": "Matrilysin", "gene_name": "MMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04792-1", "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29474-1", "protein_name": "Nitric oxide synthase 3", "gene_name": "NOS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63218-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "gene_name": "GNG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99873-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "PRMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16520-1", "protein_name": "Guanine nucleotide-binding protein 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"uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": "GNG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14610-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2", "gene_name": "GNGT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08254-1", "protein_name": "Stromelysin-1", "gene_name": "MMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20439495", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 55 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FCHo proteins are nucleators of clathrin-mediated endocytosis.", "journal": "Science (New York, N.Y.)", "date": "2010", "authors": "Henne WM, Boucrot E, Meinecke M, Evergren E, Vallis Y, Mittal R, McMahon HT", "reference": { "type": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RF0-1", "protein_name": "Sorting nexin-18", "gene_name": "SNX18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH8-1", "protein_name": "RalBP1-associated Eps domain-containing protein 2", "gene_name": "REPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NBV8-4", "protein_name": "Synaptotagmin-8", "gene_name": "SYT8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N9I0-1", "protein_name": "Synaptotagmin-2", "gene_name": "SYT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51809-1", "protein_name": "Vesicle-associated membrane protein 7", "gene_name": "VAMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52594-1", "protein_name": "Arf-GAP domain and FG repeat-containing protein 1", "gene_name": "AGFG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT88-1", "protein_name": "Synaptotagmin-11", "gene_name": "SYT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60641-1", "protein_name": "Clathrin coat assembly protein AP180", "gene_name": "SNAP91", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15145-1", "protein_name": "Actin-related protein 2/3 complex subunit 3", "gene_name": "ARPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5X1-1", "protein_name": "Sorting nexin-9", "gene_name": "SNX9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14247-1", "protein_name": "Src substrate cortactin", "gene_name": "CTTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95782-1", "protein_name": "AP-2 complex subunit alpha-1", "gene_name": "AP2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04114-1", "protein_name": "Apolipoprotein B-100", "gene_name": "APOB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59998-1", "protein_name": "Actin-related protein 2/3 complex subunit 4", "gene_name": "ARPC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15144-1", "protein_name": "Actin-related protein 2/3 complex subunit 2", "gene_name": "ARPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N6T3-1", "protein_name": "ADP-ribosylation factor GTPase-activating protein 1", "gene_name": "ARFGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61158-1", "protein_name": "Actin-related protein 3", "gene_name": "ACTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15511-1", "protein_name": "Actin-related protein 2/3 complex subunit 5", "gene_name": "ARPC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61160-1", "protein_name": "Actin-related protein 2", "gene_name": "ACTR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Z0R4-1", "protein_name": "Intersectin-1", "gene_name": "Itsn1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z0R6-1", "protein_name": "Intersectin-2", "gene_name": "Itsn2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P25103-1", "protein_name": "Substance-P receptor", "gene_name": "TACR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D71-1", "protein_name": "RalBP1-associated Eps domain-containing protein 1", "gene_name": "REPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53675-1", "protein_name": "Clathrin heavy chain 2", "gene_name": "CLTCL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T0N5-1", "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9WVE9-3", "protein_name": "Intersectin-1", "gene_name": "Itsn1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16871-1", "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV43-1", "protein_name": "Dyslexia-associated protein KIAA0319", "gene_name": "KIAA0319", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75146-1", "protein_name": "Huntingtin-interacting protein 1-related protein", "gene_name": "HIP1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00291-1", "protein_name": "Huntingtin-interacting protein 1", "gene_name": "HIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01185-1", "protein_name": "Vasopressin-neurophysin 2-copeptin", "gene_name": "AVP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00443-1", "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha", "gene_name": "PIK3C2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q2-1", "protein_name": "Stonin-1", "gene_name": "STON1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV40-1", "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU3-1", "protein_name": "Formin-binding protein 1", "gene_name": "FNBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61020-1", "protein_name": "Ras-related protein Rab-5B", "gene_name": "RAB5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14976-1", "protein_name": "Cyclin-G-associated kinase", "gene_name": "GAK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15836-1", "protein_name": "Vesicle-associated membrane protein 3", "gene_name": "VAMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30518-1", 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"uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15811-1", "protein_name": "Intersectin-1", "gene_name": "ITSN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09497-1", "protein_name": "Clathrin light chain B", "gene_name": "CLTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": 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"uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53680-1", "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94973-1", "protein_name": "AP-2 complex subunit alpha-2", "gene_name": "AP2A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15642-1", "protein_name": "Cdc42-interacting protein 4", "gene_name": "TRIP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": 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"url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 136, "end_pos": 136, "sequence_org": "L", "sequence_mut": "E", "comment": "Loss of function mutant which is unable to promote clathrin coated-pits formation. Binds to membrane but is unable to induce membrane tubulation. Induces the formation of large and static clathrin-coated pits.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" }, { "start_pos": 146, "end_pos": 146, "sequence_org": "K", "sequence_mut": "E", "comment": "Loss of function mutant which is unable to promote clathrin coated-pits formation. Cytosolic mutant which is unable to bind and induce membrane tubulation; when associated with E-165.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" }, { "start_pos": 165, "end_pos": 165, "sequence_org": "K", "sequence_mut": "E", "comment": "Loss of function mutant which is unable to promote clathrin coated-pits formation. Cytosolic mutant which is unable to bind and induce membrane tubulation; when associated with E-146.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" }, { "start_pos": 268, "end_pos": 268, "sequence_org": "I", "sequence_mut": "N", "comment": "Loss of function mutant which is unable to promote clathrin coated-pits formation. Binds to membrane but is unable to induce membrane tubulation. Induces the formation of large and static clathrin-coated pits.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" }, { "start_pos": 38, "end_pos": 38, "sequence_org": "F", "sequence_mut": "E", "comment": "Loss of function mutant which is unable to promote clathrin coated-pits formation. Cytosolic mutant; when associated with E-73.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" }, { "start_pos": 73, "end_pos": 73, "sequence_org": "W", "sequence_mut": "E", "comment": "Loss of function mutant which is unable to promote clathrin coated-pits formation. Cytosolic mutant; when associated with E-38.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" }, { "start_pos": 797, "end_pos": 797, "sequence_org": "K", "sequence_mut": "E", "comment": "Loss of interaction with EPS15 and ITSN1.", "evidence": [ { "database": "UniProtKB", "id": "Q3UQN2", "url": "https://www.uniprot.org/uniprotkb/Q3UQN2" }, { "database": "PubMed", "id": "20448150", "url": "https://pubmed.ncbi.nlm.nih.gov/20448150" } ], "uniprot_canonical_ac": "Q3UQN2-1" } ], "record_id": "pubmed.20448150", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 134 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The effect of epidermal growth factor receptor variant III on glioma cell migration by stimulating ERK phosphorylation through the focal adhesion kinase signaling pathway.", "journal": "Archives of biochemistry and biophysics", "date": "2010", "authors": "Liu M, Yang Y, Wang C, Sun L, Mei C, Yao W, Liu Y, Shi Y, Qiu S, Fan J, Cai X, Zha X", "reference": { "type": "PubMed", "id": "20650261", "url": "https://pubmed.ncbi.nlm.nih.gov/20650261" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01133-1", "protein_name": "Pro-epidermal growth factor", "gene_name": "EGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03135-1", "protein_name": "Caveolin-1", "gene_name": "CAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15514-1", "protein_name": "Amphiregulin", "gene_name": "AREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08069-1", 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G(I)/G(S)/G(O) subunit gamma-7", "gene_name": "GNG7", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MTJ3-1", "protein_name": "Guanine nucleotide-binding protein G(t) subunit alpha-3", "gene_name": "GNAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50150-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4", "gene_name": "GNG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50151-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10", "gene_name": "GNG10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2W3-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13", "gene_name": "GNG13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05397-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01135-1", "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA1-1", "protein_name": "Sphingosine kinase 1", "gene_name": "SPHK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08754-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-3", "gene_name": "GNAI3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63096-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-1", "gene_name": "GNAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09237-1", "protein_name": "Matrilysin", "gene_name": "MMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04792-1", "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43815-1", "protein_name": "Striatin", "gene_name": "STRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29474-1", "protein_name": "Nitric oxide synthase 3", "gene_name": "NOS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31749-1", "protein_name": "RAC-alpha serine/threonine-protein kinase", "gene_name": "AKT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63218-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "gene_name": "GNG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99873-1", "protein_name": "Protein arginine N-methyltransferase 1", "gene_name": "PRMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16520-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3", "gene_name": "GNB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04899-1", "protein_name": "Guanine nucleotide-binding protein G(i) subunit alpha-2", "gene_name": "GNAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14780-1", "protein_name": "Matrix metalloproteinase-9", "gene_name": "MMP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK08-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8", "gene_name": "GNG8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBI6-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "gene_name": "GNG12", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14775-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-5", "gene_name": "GNB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVQ6-1", "protein_name": "Palmitoyltransferase ZDHHC21", "gene_name": "ZDHHC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08253-1", "protein_name": "72 kDa type IV collagenase", "gene_name": "MMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99500-1", "protein_name": "Sphingosine 1-phosphate receptor 3", "gene_name": "S1PR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35070-1", "protein_name": "Probetacellulin", "gene_name": "BTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51636-1", "protein_name": "Caveolin-2", "gene_name": "CAV2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAV0-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-4", "gene_name": "GNB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61952-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11", "gene_name": "GNG11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62879-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2", "gene_name": "GNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63215-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3", "gene_name": "GNG3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14610-1", "protein_name": "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2", "gene_name": "GNGT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99075-1", "protein_name": "Proheparin-binding EGF-like growth factor", "gene_name": "HBEGF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08254-1", "protein_name": "Stromelysin-1", "gene_name": "MMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UW88-1", "protein_name": "Epigen", "gene_name": "EPGN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14944-1", "protein_name": "Proepiregulin", "gene_name": "EREG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01133", "url": "https://www.uniprot.org/uniprotkb/P01133" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20650261", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 55 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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