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kinase kinase 2", "gene_name": "MAP2K2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQM7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "CAMK2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36873-1", "protein_name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "gene_name": "PPP1CC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35232-1", "protein_name": "Prohibitin 1", "gene_name": "PHB1; PHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { 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"https://www.uniprot.org/uniprotkb/Q13554" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24121489", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], 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ERK pathway activation with polarity and tumorigenic growth.", "journal": "Molecular cell", "date": "2013", "authors": "Young LC, Hartig N, Munoz-Alegre M, Oses-Prieto JA, Durdu S, Bender S, Vijayakumar V, Vietri Rudan M, Gewinner C, Henderson S, Jathoul AP, Ghatrora R, Lythgoe MF, Burlingame AL, Rodriguez-Viciana P", "reference": { "type": "PubMed", "id": "24211266", "url": "https://pubmed.ncbi.nlm.nih.gov/24211266" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13554-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "CAMK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36507-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 2", "gene_name": "MAP2K2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQM7-1", "protein_name": 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"protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13557-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02750-1", "protein_name": "Dual 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"protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A 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"Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13554", "url": "https://www.uniprot.org/uniprotkb/Q13554" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24347342", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Discovery of 1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3- d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a pan-RAF inhibitor with minimal paradoxical activation and activity against BRAF or RAS mutant tumor cells.", "journal": "Journal of medicinal chemistry", "date": "2015", "authors": "Henry JR, Kaufman MD, Peng SB, Ahn YM, Caldwell TM, Vogeti L, Telikepalli H, Lu WP, Hood MM, Rutkoski TJ, Smith BD, Vogeti S, Miller D, Wise SC, Chun L, Zhang X, Zhang Y, Kays L, Hipskind PA, Wrobleski AD, Lobb KL, Clay JM, Cohen JD, Walgren JL, McCann D, Patel P, Clawson DK, Guo S, Manglicmot D, Groshong C, Logan C, Starling JJ, Flynn DL", "reference": { "type": "PubMed", "id": "25965804", "url": "https://pubmed.ncbi.nlm.nih.gov/25965804" }, 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}, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13557-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02750-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "MAP2K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVT5-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "KSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13555-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit gamma", "gene_name": "CAMK2G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14807-1", "protein_name": "Ras-related protein 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel rasopathy caused by recurrent de novo missense mutations in PPP1CB closely resembles Noonan syndrome with loose anagen hair.", "journal": "American journal of medical genetics. 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"GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36873-1", "protein_name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "gene_name": "PPP1CC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07817-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "BCL2L1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75608-1", "protein_name": "Acyl-protein thioesterase 1", "gene_name": "LYPLA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35232-1", "protein_name": "Prohibitin 1", "gene_name": "PHB1; PHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y397-1", "protein_name": "Palmitoyltransferase ZDHHC9", "gene_name": "ZDHHC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GS6-1", "protein_name": "Alpha/beta hydrolase domain-containing protein 17A", "gene_name": "ABHD17A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z5G4-1", "protein_name": "Golgin subfamily A member 7", "gene_name": "GOLGA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13557-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02750-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "MAP2K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04759-1", "protein_name": "Protein kinase C theta type", "gene_name": "PRKCQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVT5-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "KSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60725-1", "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase", "gene_name": "ICMT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13555-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit gamma", "gene_name": "CAMK2G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14807-1", "protein_name": "Ras-related protein M-Ras", "gene_name": "MRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6R6M4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17", "gene_name": "USP17L2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16584-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 11", "gene_name": "MAP3K11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49356-1", "protein_name": "Protein farnesyltransferase subunit beta", "gene_name": "FNTB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y256-1", "protein_name": "CAAX prenyl protease 2", "gene_name": "RCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VST6-1", "protein_name": "Alpha/beta hydrolase domain-containing protein 17B", "gene_name": "ABHD17B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PCB6-1", "protein_name": "Alpha/beta hydrolase domain-containing protein 17C", "gene_name": "ABHD17C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14738-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "gene_name": "PPP2R5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13554", "url": "https://www.uniprot.org/uniprotkb/Q13554" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.28666118", "abstract": "", "glycosylation": 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Cancer", "date": "2017", "authors": "Karoulia Z, Gavathiotis E, Poulikakos PI", "reference": { "type": "PubMed", "id": "28984291", "url": "https://pubmed.ncbi.nlm.nih.gov/28984291" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13554-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "CAMK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36507-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 2", "gene_name": "MAP2K2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQM7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "CAMK2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36873-1", "protein_name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "gene_name": "PPP1CC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35232-1", "protein_name": "Prohibitin 1", "gene_name": "PHB1; PHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13557-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02750-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "MAP2K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVT5-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "KSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13555-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit gamma", "gene_name": "CAMK2G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14807-1", "protein_name": "Ras-related protein M-Ras", "gene_name": "MRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16584-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 11", "gene_name": "MAP3K11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13554", "url": "https://www.uniprot.org/uniprotkb/Q13554" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7744815", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"protein_name": "Dual specificity mitogen-activated protein kinase kinase 2", "gene_name": "MAP2K2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q61097-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "Ksr1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQM7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "CAMK2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36873-1", "protein_name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "gene_name": "PPP1CC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35232-1", "protein_name": "Prohibitin 1", "gene_name": "PHB1; PHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic 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"Mitogen-activated protein kinase kinase kinase 11", "gene_name": "MAP3K11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14738-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "gene_name": "PPP2R5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction.", "journal": "Cell", "date": "1995", "authors": "Sundaram M, Han M", "reference": { "type": "PubMed", "id": "8521513", "url": "https://pubmed.ncbi.nlm.nih.gov/8521513" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13554-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "CAMK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36507-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 2", "gene_name": "MAP2K2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQM7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase 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}, { "uniprot_canonical_ac": "P36873-1", "protein_name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "gene_name": "PPP1CC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35232-1", "protein_name": "Prohibitin 1", "gene_name": "PHB1; PHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": 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"uniprot_canonical_ac": "Q16584-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 11", "gene_name": "MAP3K11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14738-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "gene_name": "PPP2R5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13554", "url": "https://www.uniprot.org/uniprotkb/Q13554" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8521514", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q9UQM7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit alpha", "gene_name": "CAMK2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60674-1", "protein_name": "Tyrosine-protein kinase JAK2", "gene_name": "JAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36873-1", "protein_name": "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "gene_name": "PPP1CC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35232-1", "protein_name": "Prohibitin 1", "gene_name": "PHB1; PHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13557-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02750-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "MAP2K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVT5-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "KSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13555-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit gamma", "gene_name": "CAMK2G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14807-1", "protein_name": "Ras-related protein M-Ras", "gene_name": "MRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16584-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 11", "gene_name": "MAP3K11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14738-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "gene_name": "PPP2R5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13554", "url": "https://www.uniprot.org/uniprotkb/Q13554" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8637718", "abstract": "", "glycosylation": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.", "journal": "Journal of neurochemistry", "date": "1998", "authors": "Itoh T, Itoh A, Horiuchi K, Pleasure D", "reference": { "type": "PubMed", "id": "9648857", "url": "https://pubmed.ncbi.nlm.nih.gov/9648857" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13554-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit beta", "gene_name": "CAMK2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48058-1", "protein_name": "Glutamate receptor 4", "gene_name": "GRIA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42261-1", "protein_name": "Glutamate receptor 1", "gene_name": "GRIA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42263-1", "protein_name": "Glutamate receptor 3", "gene_name": "GRIA3", 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Mol. Biol.", "date": "2007", "authors": "Woo Eui-Jeon, Jeong Dae Gwin, Lim Mi-Youn, Jun Kim Seung, Kim Kyung-Jin, Yoon Sei-Mee, Park Byoung-Chul, Ryu Seong Eon", "reference": { "type": "PubMed", "id": "17870090", "url": "https://pubmed.ncbi.nlm.nih.gov/17870090" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14995-1", "protein_name": "Nuclear receptor subfamily 1 group D member 2", "gene_name": "NR1D2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14995", "url": "https://www.uniprot.org/uniprotkb/Q14995" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17870090", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PKN delays mitotic timing by inhibition of Cdc25C: possible involvement of PKN in the regulation of cell division.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2001", "authors": "Misaki K, Mukai H, Yoshinaga C, Oishi K, Isagawa T, Takahashi M, Ohsumi K, Kishimoto T, Ono Y", "reference": { "type": "PubMed", "id": "11134534", "url": "https://pubmed.ncbi.nlm.nih.gov/11134534" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16512-1", "protein_name": "Serine/threonine-protein kinase N1", "gene_name": "PKN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61586-1", "protein_name": "Transforming protein RhoA", "gene_name": "RHOA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08134-1", "protein_name": "Rho-related GTP-binding protein RhoC", "gene_name": "RHOC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60660-1", "protein_name": "Myosin light polypeptide 6", "gene_name": "MYL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P5Z2-1", "protein_name": "Serine/threonine-protein kinase N3", "gene_name": "PKN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35579-1", "protein_name": "Myosin-9", "gene_name": "MYH9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31947-1", "protein_name": "14-3-3 protein sigma", "gene_name": "SFN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14950-1", "protein_name": "Myosin regulatory light chain 12B", "gene_name": "MYL12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62140-1", "protein_name": "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "gene_name": "PPP1CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62745-1", "protein_name": "Rho-related GTP-binding protein RhoB", "gene_name": "RHOB", "tax_name": "Human" }, { 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AMPK- and caMK-dependent phosphorylation and the subsequent nuclear export. 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Does not affect phosphorylation by PKN1 and PKN2.", "evidence": [ { "database": "UniProtKB", "id": "Q9UQL6", "url": "https://www.uniprot.org/uniprotkb/Q9UQL6" }, { "database": "PubMed", "id": "11081517", "url": "https://pubmed.ncbi.nlm.nih.gov/11081517" }, { "database": "PubMed", "id": "20188095", "url": "https://pubmed.ncbi.nlm.nih.gov/20188095" }, { "database": "PubMed", "id": "18184930", "url": "https://pubmed.ncbi.nlm.nih.gov/18184930" } ], "uniprot_canonical_ac": "Q9UQL6-1" }, { "start_pos": 291, "end_pos": 291, "sequence_org": "S", "sequence_mut": "A", "comment": "Does not affect phosphorylation by PKC.", "evidence": [ { "database": "UniProtKB", "id": "Q9UQL6", "url": "https://www.uniprot.org/uniprotkb/Q9UQL6" }, { "database": "PubMed", "id": "20188095", "url": "https://pubmed.ncbi.nlm.nih.gov/20188095" } ], "uniprot_canonical_ac": "Q9UQL6-1" }, { "start_pos": 292, "end_pos": 292, "sequence_org": "T", "sequence_mut": "A", "comment": "Abolishes phosphorylation by PKC.", "evidence": [ { "database": "UniProtKB", "id": "Q9UQL6", "url": "https://www.uniprot.org/uniprotkb/Q9UQL6" }, { "database": "PubMed", "id": "20188095", "url": "https://pubmed.ncbi.nlm.nih.gov/20188095" } ], "uniprot_canonical_ac": "Q9UQL6-1" } ], "phosphorylation": [ { "start_pos": 292, "end_pos": 292, "kinase_uniprot_canonical_ac": "Q16512-1", "kinase_gene_name": "PKN1", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q9UQL6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9UQL6" }, { "database": "PubMed", "id": "20188095", "url": "https://pubmed.ncbi.nlm.nih.gov/20188095" } ], "site_lbl": "Thr292", "uniprot_canonical_ac": "Q9UQL6-1" }, { "start_pos": 292, "end_pos": 292, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by PKC", "evidence": [ { "database": "UniProtKB", "id": "Q9UQL6", "url": "https://www.uniprot.org/uniprotkb/Q9UQL6" }, { "database": "iPTMnet", "id": "Q9UQL6", 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protein", "gene_name": "GFAP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16512", "url": "https://www.uniprot.org/uniprotkb/Q16512" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9175763", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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