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"biomarker_canonical_id": "AN6334", "assessed_biomarker_entity": [ "Interleukin-4" ], "biomarker_id": "AN6334-2", "biomarker": [ "increased IL4 level" ], "condition": { "id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "name_list": [ "prostate cancer", "NGP - new growth of prostate", "hereditary prostate cancer", "malignant tumor of the prostate", "prostate cancer, familial", "prostate neoplasm", "prostatic cancer", "prostatic neoplasm", "tumor of the prostate", "prostate cancer, hereditary, X-linked 1", "HPCX1", "prostate cancer, hereditary, X-linked 2", "HPCX2", "prostate cancer, hereditary, 1", "RNASEL familial prostate cancer", "familial prostate cancer caused by mutation in RNASEL", "prostate cancer 1", "prostate cancer, hereditary, type 1", "HPC1", "prostate cancer, 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hereditary, 11", "HPC11", "prostate cancer, hereditary, 14", "HPC14", "prostate cancer, hereditary, 15", "HPC15", "prostate cancer, hereditary", "Prostate cancer, hereditary, 1", "Prostate cancer, hereditary, 9", "Prostate cancer, hereditary, 12", "Prostate cancer, hereditary, 13", "Prostate cancer, hereditary, 11", "Prostate cancer" ], "id_list": [ "DOID:10283", "MONDO:0010257", "MONDO:0010405", "MONDO:0011098", "MONDO:0011270", "MONDO:0012093", "MONDO:0012094", "MONDO:0012244", "MONDO:0012300", "MONDO:0012470", "MONDO:0012597", "MONDO:0012620", "MONDO:0012741", "MONDO:0012758", "MONDO:0012768", "MONDO:0012769", "MONDO:0012770", "MONDO:0700275", "MIM:601518", "MIM:610997", "MIM:611868", "MIM:611928", "MIM:611955", "MIM:176807" ] } } ], "record_id": "pubmed.24213139", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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Immunol.", "date": "1989", "authors": "Delespesse G, Sarfati M, Peleman R", "reference": { "type": "PubMed", "id": "2521231", "url": "https://pubmed.ncbi.nlm.nih.gov/2521231" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P05112-1", "protein_name": "Interleukin-4", "gene_name": "IL4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P05112", "url": "https://www.uniprot.org/uniprotkb/P05112" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2521231", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.", "journal": "J. Immunol.", "date": "1989", "authors": "Arai N, Nomura D, Villaret D, DeWaal Malefijt R, Seiki M, Yoshida M, Minoshima S, Fukuyama R, Maekawa M, Kudoh J", "reference": { "type": "PubMed", "id": "2535858", "url": "https://pubmed.ncbi.nlm.nih.gov/2535858" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P05112-1", "protein_name": "Interleukin-4", "gene_name": "IL4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P05112", "url": "https://www.uniprot.org/uniprotkb/P05112" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2535858", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM.", "journal": "J. 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U.S.A.", "date": "1990", "authors": "Micanovic R, Gerber L D, Berger J, Kodukula K, Udenfriend S", "reference": { "type": "PubMed", "id": "2153284", "url": "https://pubmed.ncbi.nlm.nih.gov/2153284" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P05187-1", "protein_name": "Alkaline phosphatase, placental type", "gene_name": "ALPP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P05187", "url": "https://www.uniprot.org/uniprotkb/P05187" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2153284", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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potential biomarker of severity and prognosis in intracerebral hemorrhage.", "journal": "Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association", "date": "2024-01", "authors": "Wu Guangying, Li Shuhua, Luo Min, Li Xiaotian, Zhu Xinghua, Zhang Junhuai, He Qian, Yang Qian, Zhao Guojiang, Luo Shasha, Yang Zhijie", "reference": { "type": "PubMed", "id": "37952310", "url": "https://pubmed.ncbi.nlm.nih.gov/37952310" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P05187-1", "protein_name": "Alkaline phosphatase, placental type", "gene_name": "ALPP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P05187", "url": "https://www.uniprot.org/uniprotkb/P05187" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37952310", "abstract": "", "glycosylation": [], "mutagenesis": 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Commun.", "date": "1983", "authors": "Ezra E, Blacher R, Udenfriend S", "reference": { "type": "PubMed", "id": "6651840", "url": "https://pubmed.ncbi.nlm.nih.gov/6651840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P05187-1", "protein_name": "Alkaline phosphatase, placental type", "gene_name": "ALPP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P05187", "url": "https://www.uniprot.org/uniprotkb/P05187" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.6651840", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"journal": "J. Biol. Chem.", "date": "2002", "authors": "Dawson Simon, Apcher Sebastien, Mee Maureen, Higashitsuji Hiroaki, Baker Rohan, Uhle Stefan, Dubiel Wolfgang, Fujita Jun, Mayer R John", "reference": { "type": "PubMed", "id": "11779854", "url": "https://pubmed.ncbi.nlm.nih.gov/11779854" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75832-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 10", "gene_name": "PSMD10", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75832", "url": "https://www.uniprot.org/uniprotkb/O75832" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11779854", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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Biol. 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