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        "title": "The NS3 proteinase domain of hepatitis C virus is a zinc-containing enzyme.",
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        "authors": "Stempniak M, Hostomska Z, Nodes BR, Hostomsky Z",
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            {
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                "comment": "No effect on zinc-binding by serine protease NS3.",
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/8389908"
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                ],
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            {
                "start_pos": 1136,
                "end_pos": 1136,
                "sequence_org": "H",
                "sequence_mut": "A",
                "comment": "No effect on polyprotein processing. No effect on zinc-binding by serine protease/helicase NS3.",
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                        "id": "P26662",
                        "url": "https://www.uniprot.org/uniprotkb/P26662"
                    },
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                "comment": "Complete loss of serine protease NS3 activity. No effect on zinc-binding by serine protease NS3.",
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                        "id": "9060645",
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            {
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                "sequence_org": "H",
                "sequence_mut": "A",
                "comment": "No effect on polyprotein processing. Reduces zinc-binding by serine protease NS3.",
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