[ { "title": "Human airway epithelia express a beta-defensin.", "journal": "Am. J. Respir. Cell Mol. Biol.", "date": "1997", "authors": "McCray PB Jr, Bentley L", "reference": { "type": "PubMed", "id": "9070620", "url": "https://pubmed.ncbi.nlm.nih.gov/9070620" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P60022-1", "protein_name": "Beta-defensin 1", "gene_name": "DEFB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P60022", "url": "https://www.uniprot.org/uniprotkb/P60022" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9070620", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.", "journal": "Genomics", "date": "1997", "authors": "Liu L, Zhao C, Heng H H, Ganz T", "reference": { "type": "PubMed", "id": "9268634", "url": "https://pubmed.ncbi.nlm.nih.gov/9268634" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P60022-1", "protein_name": "Beta-defensin 1", "gene_name": "DEFB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P60022", "url": "https://www.uniprot.org/uniprotkb/P60022" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9268634", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.", "journal": "The Journal of clinical investigation", "date": "1998", "authors": "Valore EV, Park CH, Quayle AJ, Wiles KR, McCray PB Jr, Ganz T", "reference": { "type": "PubMed", "id": "9541493", "url": "https://pubmed.ncbi.nlm.nih.gov/9541493" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P60022-1", "protein_name": "Beta-defensin 1", "gene_name": "DEFB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51684-1", "protein_name": "C-C chemokine receptor type 6", "gene_name": "CCR6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZN7-1", "protein_name": "Beta-defensin 107", "gene_name": "DEFB107A; DEFB107B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N104-1", "protein_name": "Beta-defensin 106", "gene_name": "DEFB106A; DEFB106B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NET1-1", "protein_name": "Beta-defensin 108B", "gene_name": "DEFB108B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NG35-1", "protein_name": "Beta-defensin 105", "gene_name": "DEFB105A; DEFB105B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTQ1-1", "protein_name": "Beta-defensin 104", "gene_name": "DEFB104A; DEFB104B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P81534-1", "protein_name": "Beta-defensin 103", "gene_name": "DEFB103A; DEFB103B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KP9-1", "protein_name": "Beta-defensin 135", "gene_name": "DEFB135", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4QY38-1", "protein_name": "Beta-defensin 134", "gene_name": "DEFB134", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z7B7-1", "protein_name": "Beta-defensin 132", "gene_name": "DEFB132", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1M3-1", "protein_name": "Beta-defensin 129", "gene_name": "DEFB129", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1M4-1", "protein_name": "Beta-defensin 127", "gene_name": "DEFB127", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59861-1", "protein_name": "Beta-defensin 131A", "gene_name": "DEFB131A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ6-1", "protein_name": "Beta-defensin 114", "gene_name": "DEFB114", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ7-1", "protein_name": "Beta-defensin 113", "gene_name": "DEFB113", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ8-1", "protein_name": "Beta-defensin 112", "gene_name": "DEFB112", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N688-1", "protein_name": "Beta-defensin 123", "gene_name": "DEFB123", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N690-1", "protein_name": "Beta-defensin 119", "gene_name": "DEFB119", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NES8-1", "protein_name": "Beta-defensin 124", "gene_name": "DEFB124", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ1-1", "protein_name": "Beta-defensin 133", "gene_name": "DEFB133", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15263-1", "protein_name": "Defensin beta 4A", "gene_name": "DEFB4A; DEFB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N687-1", "protein_name": "Beta-defensin 125", "gene_name": "DEFB125", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PH6-1", "protein_name": "Defensin beta 118", "gene_name": "DEFB118", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41597-1", "protein_name": "C-C chemokine receptor type 2", "gene_name": "CCR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MXU0-1", "protein_name": "Putative beta-defensin 108A", "gene_name": "DEFB108A; DEFB108C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP73-1", "protein_name": "Beta-defensin 130B", "gene_name": "DEFB130B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP74-1", "protein_name": "Beta-defensin 130A", "gene_name": "DEFB130A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KP8-1", "protein_name": "Defensin beta 136", "gene_name": "DEFB136", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ4-1", "protein_name": "Beta-defensin 116", "gene_name": "DEFB116", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ5-1", "protein_name": "Beta-defensin 115", "gene_name": "DEFB115", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KQ9-1", "protein_name": "Beta-defensin 110", "gene_name": "DEFB110", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30KR1-1", "protein_name": "Beta-defensin 109B", "gene_name": "DEFB109B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5J5C9-1", "protein_name": "Beta-defensin 121", "gene_name": "DEFB121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z7B8-1", "protein_name": "Beta-defensin 128", "gene_name": "DEFB128", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW3-1", "protein_name": "Beta-defensin 126", "gene_name": "DEFB126", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P60022", "url": "https://www.uniprot.org/uniprotkb/P60022" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9541493", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 38 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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recruited in an SH2-dependent manner to the erythropoietin receptor.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Mason JM, Beattie BK, Liu Q, Dumont DJ, Barber DL", "reference": { "type": "PubMed", "id": "10660611", "url": "https://pubmed.ncbi.nlm.nih.gov/10660611" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14753-1", "protein_name": "Erythropoietin receptor", "gene_name": "Epor", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ES52-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "gene_name": "Inpp5d", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 426, "end_pos": 426, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by JAK2", "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" }, { "database": "IntAct", "id": "P19235", "url": "https://www.ebi.ac.uk/intact/interactors/id:P19235*" }, { "database": "iPTMnet", "id": "P19235", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19235" }, { "database": "PubMed", "id": "10660611", "url": "https://pubmed.ncbi.nlm.nih.gov/10660611" }, { "database": "PubMed", "id": "10882725", "url": "https://pubmed.ncbi.nlm.nih.gov/10882725" }, { "database": "PubMed", "id": "7528537", "url": "https://pubmed.ncbi.nlm.nih.gov/7528537" } ], "site_lbl": "Tyr426", "uniprot_canonical_ac": "P19235-1" }, { "start_pos": 455, "end_pos": 455, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": 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"O35718-1", "protein_name": "Suppressor of cytokine signaling 3", "gene_name": "Socs3", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 426, "end_pos": 426, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by JAK2", "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" }, { "database": "IntAct", "id": "P19235", "url": "https://www.ebi.ac.uk/intact/interactors/id:P19235*" }, { "database": "iPTMnet", "id": "P19235", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P19235" }, { "database": "PubMed", "id": "10660611", "url": "https://pubmed.ncbi.nlm.nih.gov/10660611" }, { "database": "PubMed", "id": 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No effect on binding to EPOR.", "evidence": [ { "database": "UniProtKB", "id": "O35718", "url": "https://www.uniprot.org/uniprotkb/O35718" }, { "database": "PubMed", "id": "10882725", "url": "https://pubmed.ncbi.nlm.nih.gov/10882725" } ], "uniprot_canonical_ac": "O35718-1" }, { "start_pos": 25, "end_pos": 25, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of LIF/EPO-induced signal transduction suppression. Abolishes binding to JAK2 and to EPOR.", "evidence": [ { "database": "UniProtKB", "id": "O35718", "url": "https://www.uniprot.org/uniprotkb/O35718" }, { "database": "PubMed", "id": "10882725", "url": "https://pubmed.ncbi.nlm.nih.gov/10882725" } ], "uniprot_canonical_ac": "O35718-1" }, { "start_pos": 45, "end_pos": 45, "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes binding to EPOR. No effect on binding to JAK2.", "evidence": [ { "database": "UniProtKB", "id": "O35718", "url": "https://www.uniprot.org/uniprotkb/O35718" }, { "database": "PubMed", "id": "10882725", "url": "https://pubmed.ncbi.nlm.nih.gov/10882725" } ], "uniprot_canonical_ac": "O35718-1" }, { "start_pos": 71, "end_pos": 71, "sequence_org": "R", "sequence_mut": "K", "comment": "Little effect on LIF-induced signal transduction suppression. Loss of EPO-induced signal transduction suppression. Abolishes binding to JAK2 and EPOR.", "evidence": [ { "database": "UniProtKB", "id": "O35718", "url": "https://www.uniprot.org/uniprotkb/O35718" }, { "database": "PubMed", "id": "10882725", "url": "https://pubmed.ncbi.nlm.nih.gov/10882725" } ], "uniprot_canonical_ac": "O35718-1" } ], "record_id": "pubmed.10882725", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Increased cell surface expression of C-terminal truncated erythropoietin receptors in polycythemia.", "journal": "Eur. J. Haematol.", "date": "2001", "authors": "Motohashi T, Nakamura Y, Osawa M, Hiroyama T, Iwama A, Shibuya A, Nakauchi H", "reference": { "type": "PubMed", "id": "11722595", "url": "https://pubmed.ncbi.nlm.nih.gov/11722595" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11722595", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation.", "journal": "Blood", "date": "2002", "authors": "Kirito K, Nakajima K, Watanabe T, Uchida M, Tanaka M, Ozawa K, Komatsu N", "reference": { "type": "PubMed", "id": "11756159", "url": "https://pubmed.ncbi.nlm.nih.gov/11756159" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 456, "end_pos": 456, "sequence_org": "Y", "sequence_mut": "F", "comment": "Inhibition of STAT1/STAT3 activity. No effect on STAT5 activity. Some loss of SOCS3 binding.", "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" }, { "database": "PubMed", "id": "12027890", "url": "https://pubmed.ncbi.nlm.nih.gov/12027890" }, { "database": "PubMed", "id": "11756159", "url": "https://pubmed.ncbi.nlm.nih.gov/11756159" } ], "uniprot_canonical_ac": "P19235-1" }, { "start_pos": 468, "end_pos": 468, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on STAT1/STAT3 nor STAT5 activity.", "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" }, { "database": "PubMed", "id": "11756159", "url": "https://pubmed.ncbi.nlm.nih.gov/11756159" } ], "uniprot_canonical_ac": "P19235-1" } ], "record_id": "pubmed.11756159", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and characterization of a family of proteins associated with Mpl.", "journal": "J. 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Hematol.", "date": "1991", "authors": "Ehrenman K, St John T", "reference": { "type": "PubMed", "id": "1654273", "url": "https://pubmed.ncbi.nlm.nih.gov/1654273" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1654273", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Isolation of a cDNA encoding a potential soluble receptor for human erythropoietin.", "journal": "Gene", "date": "1991", "authors": "Todokoro K, Kuramochi S, Nagasawa T, Abe T, Ikawa Y", "reference": { "type": "PubMed", "id": "1657727", "url": "https://pubmed.ncbi.nlm.nih.gov/1657727" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": 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erythropoietin receptor gene.", "journal": "Genomics", "date": "1991", "authors": "Penny LA, Forget BG", "reference": { "type": "PubMed", "id": "1664413", "url": "https://pubmed.ncbi.nlm.nih.gov/1664413" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1664413", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning of the human erythropoietin receptor gene.", "journal": "Blood", "date": "1991", "authors": "Noguchi C T, Bae K S, Chin K, Wada Y, Schechter A N, Hankins W D", "reference": { "type": "PubMed", "id": "1668606", "url": "https://pubmed.ncbi.nlm.nih.gov/1668606" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": 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], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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erythropoietin receptor.", "journal": "Blood", "date": "1991", "authors": "Maouche L, Tournamille C, Hattab C, Boffa G, Cartron JP, Chretien S", "reference": { "type": "PubMed", "id": "1668607", "url": "https://pubmed.ncbi.nlm.nih.gov/1668607" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19235-1", "protein_name": "Erythropoietin receptor", "gene_name": "EPOR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19235", "url": "https://www.uniprot.org/uniprotkb/P19235" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1668607", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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Biol. 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Autocatalytic processing can be restored by treatment with hydroxylamine.", "evidence": [ { "database": "UniProtKB", "id": "Q9C000", "url": "https://www.uniprot.org/uniprotkb/Q9C000" }, { "database": "PubMed", "id": "22665479", "url": "https://pubmed.ncbi.nlm.nih.gov/22665479" } ], "uniprot_canonical_ac": "Q9C000-1" }, { "start_pos": 1211, "end_pos": 1211, "sequence_org": "S", "sequence_mut": "A", "comment": "Partial loss of autocatalytic processing and of IL1B release.", "evidence": [ { "database": "UniProtKB", "id": "Q9C000", "url": "https://www.uniprot.org/uniprotkb/Q9C000" }, { "database": "PubMed", "id": "22665479", "url": "https://pubmed.ncbi.nlm.nih.gov/22665479" } ], "uniprot_canonical_ac": "Q9C000-1" }, { "start_pos": 1212, "end_pos": 1212, "sequence_org": "F", "sequence_mut": "A", "comment": "Complete loss of autocatalytic processing and of IL1B release.", "evidence": [ { "database": "UniProtKB", "id": "Q9C000", "url": "https://www.uniprot.org/uniprotkb/Q9C000" }, { "database": "PubMed", "id": "33093214", "url": "https://pubmed.ncbi.nlm.nih.gov/33093214" }, { "database": "PubMed", "id": "22665479", "url": "https://pubmed.ncbi.nlm.nih.gov/22665479" } ], "uniprot_canonical_ac": "Q9C000-1" }, { "start_pos": 1213, "end_pos": 1213, "sequence_org": "S", "sequence_mut": "A", "comment": "Complete loss of autocatalytic processing and of IL1B release. 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