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Mol. Genet.", "date": "2005", "authors": "Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S", "reference": { "type": "PubMed", "id": "16203747", "url": "https://pubmed.ncbi.nlm.nih.gov/16203747" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BVA0-1", "protein_name": "Katanin p80 WD40 repeat-containing subunit B1", "gene_name": "KATNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8BG40-1", "protein_name": "Katanin p80 WD40 repeat-containing subunit B1", "gene_name": "Katnb1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P63005-1", "protein_name": "Platelet-activating factor acetylhydrolase IB subunit beta", "gene_name": "Pafah1b1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZM8-1", "protein_name": "Nuclear distribution protein nudE-like 1", "gene_name": "NDEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ERR1-1", "protein_name": "Nuclear distribution protein nudE-like 1", "gene_name": "Ndel1", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BVA0", "url": "https://www.uniprot.org/uniprotkb/Q9BVA0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 198, "end_pos": 198, "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces phosphorylation by CDK5 and impairs interaction with YWHAE. 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J. Hum. 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[] } ] }, { "title": "Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution.", "journal": "Nat. 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Biol.", "date": "2000", "authors": "Hanson M A, Stevens R C", "reference": { "type": "PubMed", "id": "10932255", "url": "https://pubmed.ncbi.nlm.nih.gov/10932255" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P63027", "url": "https://www.uniprot.org/uniprotkb/P63027" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10932255", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2011", "authors": "Koo Seong Joo, Markovic Stefan, Puchkov Dmytro, Mahrenholz Carsten C, Beceren-Braun Figen, Maritzen Tanja, Dernedde Jens, Volkmer Rudolf, Oschkinat Hartmut, Haucke Volker", "reference": { "type": "PubMed", "id": "21808019", "url": "https://pubmed.ncbi.nlm.nih.gov/21808019" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13492-1", "protein_name": "Phosphatidylinositol-binding clathrin assembly protein", "gene_name": "PICALM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P63027", "url": "https://www.uniprot.org/uniprotkb/P63027" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21808019", "abstract": "", "glycosylation": [], 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"database": "UniProtKB", "id": "P23763", "url": "https://www.uniprot.org/uniprotkb/P23763" }, { "database": "PubMed", "id": "22289120", "url": "https://pubmed.ncbi.nlm.nih.gov/22289120" } ], "uniprot_canonical_ac": "P23763-1" }, { "start_pos": 48, "end_pos": 48, "sequence_org": "I", "sequence_mut": "M", "comment": "1000-fold increase in susceptibility to C.botulinum BoNT/D, no change in susceptibility to BoNT/B or BoNT/F.", "evidence": [ { "database": "UniProtKB", "id": "P23763", "url": "https://www.uniprot.org/uniprotkb/P23763" }, { "database": "PubMed", "id": "22289120", "url": "https://pubmed.ncbi.nlm.nih.gov/22289120" } ], "uniprot_canonical_ac": "P23763-1" }, { "start_pos": 81, "end_pos": 81, "sequence_org": "S", "sequence_mut": "T", "comment": "No change in susceptibility to C.botulinum BoNT/B, BoNT/D or BoNT/F.", "evidence": [ { "database": "UniProtKB", "id": "P23763", "url": "https://www.uniprot.org/uniprotkb/P23763" }, { "database": "PubMed", "id": "22289120", "url": 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toxins.", "journal": "Journal of cell science", "date": "2012", "authors": "Peng L, Berntsson RP, Tepp WH, Pitkin RM, Johnson EA, Stenmark P, Dong M", "reference": { "type": "PubMed", "id": "22454523", "url": "https://pubmed.ncbi.nlm.nih.gov/22454523" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23763-1", "protein_name": "Vesicle-associated membrane protein 1", "gene_name": "VAMP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P63027", "url": "https://www.uniprot.org/uniprotkb/P63027" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22454523", 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cleaves VAMP/synaptobrevin at a single Ala-Ala peptide bond.", "journal": "The Journal of biological chemistry", "date": "1994", "authors": "Schiavo G, Malizio C, Trimble WS, Polverino de Laureto P, Milan G, Sugiyama H, Johnson EA, Montecucco C", "reference": { "type": "PubMed", "id": "8051110", "url": "https://pubmed.ncbi.nlm.nih.gov/8051110" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21579-1", "protein_name": "Synaptotagmin-1", "gene_name": "SYT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23763-1", "protein_name": "Vesicle-associated membrane protein 1", "gene_name": "VAMP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P63027", "url": "https://www.uniprot.org/uniprotkb/P63027" } ], "common_name": "Human", 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J.", "date": "1996", "authors": "Jagadish MN, Fernandez CS, Hewish DR, Macaulay SL, Gough KH, Grusovin J, Verkuylen A, Cosgrove L, Alafaci A, Frenkel MJ, Ward CW", "reference": { "type": "PubMed", "id": "8760387", "url": "https://pubmed.ncbi.nlm.nih.gov/8760387" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P63027-1", "protein_name": "Vesicle-associated membrane protein 2", "gene_name": "VAMP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60880-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "SNAP25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12846-1", "protein_name": "Syntaxin-4", "gene_name": "STX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P63027", "url": "https://www.uniprot.org/uniprotkb/P63027" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": 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