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"DOID:0111390", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111390", "name": "Hurler-Pfaundler syndrome", "description": "" }, { "id": "DOID:0111390", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111390", "name": "L-iduronidase deficiency, Hurler type", "description": "" }, { "id": "DOID:0111390", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111390", "name": "MPS1-H", "description": "" }, { "id": "DOID:0111390", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111390", "name": "Mucopolysaccharidosis type I severe form", "description": "" }, { "id": "DOID:0111390", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111390", "name": "dysostosis multiplex", "description": "" }, { "id": "DOID:0111390", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111390", "name": "gargoylism", "description": "" }, { "id": "MONDO:0011758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011758", "name": "Hurler syndrome", "description": "Hurler syndrome is the most severe form of mucopolysaccharidosis type 1 (MPS1), a rare lysosomal storage disease, characterized by skeletal abnormalities, cognitive impairment, heart disease, respiratory problems, enlarged liver and spleen, characteristic facies and reduced life expectancy." }, { "id": "MONDO:0011758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011758", "name": "Hurler disease", "description": "" }, { "id": "MONDO:0011758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011758", "name": "Hurler syndrome", "description": "" }, { "id": "MONDO:0011758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011758", "name": "MPS I H", "description": "" }, { "id": "MONDO:0011758", "resource": "MONDO", "url": 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"https://disease-ontology.org/term/DOID:0060222", "name": "mucopolysaccharidosis type V", "description": "" }, { "id": "MONDO:0011760", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011760", "name": "Scheie syndrome", "description": "Scheie syndrome is the mildest form of mucopolysaccharidosis type 1 (MPS1), a rare lysosomal storage disease, characterized by skeletal deformities and a delay in motor development." }, { "id": "MONDO:0011760", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011760", "name": "MPS I S", "description": "" }, { "id": "MONDO:0011760", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011760", "name": "MPS1S", "description": "" }, { "id": "MONDO:0011760", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011760", "name": "MPSIS", "description": "" }, { "id": "MONDO:0011760", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011760", 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the metastatic features of triple negative breast cancer.", "journal": "Oncology research", "date": "2023", "authors": "Choi Jin-Ho, Park Joo Dong, Choi Seung Hee, Ko Eun-Su, Jang Hye Jung, Park Kyung-Soon", "reference": { "type": "PubMed", "id": "38188675", "url": "https://pubmed.ncbi.nlm.nih.gov/38188675" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P47928-1", "protein_name": "DNA-binding protein inhibitor ID-4", "gene_name": "ID4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41970-1", "protein_name": "ETS domain-containing protein Elk-3", "gene_name": "ELK3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P47928", "url": "https://www.uniprot.org/uniprotkb/P47928" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38188675", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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Biol. Chem.", "date": "1999", "authors": "Kim YO, Koh HJ, Kim SH, Jo SH, Huh JW, Jeong KS, Lee IJ, Song BJ, Huh TL", "reference": { "type": "PubMed", "id": "10601238", "url": "https://pubmed.ncbi.nlm.nih.gov/10601238" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51553-1", "protein_name": "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "gene_name": "IDH3G; PDZD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43837-1", "protein_name": "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "gene_name": "IDH3B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51553", "url": "https://www.uniprot.org/uniprotkb/P51553" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10601238", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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J.", "date": "2003", "authors": "Nie GY, Hampton A, Li Y, Findlay JK, Salamonsen LA", "reference": { "type": "PubMed", "id": "12513693", "url": "https://pubmed.ncbi.nlm.nih.gov/12513693" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P83110-1", "protein_name": "Serine protease HTRA3", "gene_name": "HTRA3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P83110", "url": "https://www.uniprot.org/uniprotkb/P83110" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12513693", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Serine proteases HTRA1 and HTRA3 are down-regulated with increasing grades of human endometrial cancer.", "journal": "Gynecol. Oncol.", "date": "2006", "authors": "Bowden MA, Di Nezza-Cossens LA, Jobling T, Salamonsen LA, Nie G", "reference": { "type": "PubMed", "id": "16650464", "url": "https://pubmed.ncbi.nlm.nih.gov/16650464" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P83110-1", "protein_name": "Serine protease HTRA3", "gene_name": "HTRA3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P83110", "url": "https://www.uniprot.org/uniprotkb/P83110" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16650464", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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}, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.", "journal": "Nature immunology", "date": "2004", "authors": "Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA", "reference": { "type": "PubMed", "id": "15184896", "url": "https://pubmed.ncbi.nlm.nih.gov/15184896" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6EBC2-1", "protein_name": "Interleukin-31", "gene_name": "IL31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99650-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "OSMR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6EAL8-1", "protein_name": "Interleukin-31", "gene_name": "Il31", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K5B1-1", "protein_name": "Interleukin-31 receptor subunit alpha", "gene_name": "Il31ra", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI17-1", "protein_name": "Interleukin-31 receptor subunit alpha", "gene_name": "IL31RA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6EBC2", "url": "https://www.uniprot.org/uniprotkb/Q6EBC2" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15184896", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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}, { "uniprot_canonical_ac": "Q99650-1", "protein_name": "Oncostatin-M-specific receptor subunit beta", "gene_name": "OSMR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NI17-1", "protein_name": "Interleukin-31 receptor subunit alpha", "gene_name": "IL31RA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6EBC2", "url": "https://www.uniprot.org/uniprotkb/Q6EBC2" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 639, "end_pos": 639, "sequence_org": "Y", "sequence_mut": "A", "comment": "No effect on STAT1 and STAT3 activation. Slight decrease; when associated with A-670 and A-708.", "evidence": [ { "database": "UniProtKB", "id": "Q8NI17", "url": "https://www.uniprot.org/uniprotkb/Q8NI17" }, { "database": "PubMed", "id": "15627637", "url": "https://pubmed.ncbi.nlm.nih.gov/15627637" }, { "database": "PubMed", "id": "15194700", "url": "https://pubmed.ncbi.nlm.nih.gov/15194700" } ], "uniprot_canonical_ac": "Q8NI17-1" }, { "start_pos": 639, "end_pos": 639, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abrogates STAT5 activation. Mild effect on STAT1 activation. No effect on STAT3 activation.", "evidence": [ { "database": "UniProtKB", "id": "Q8NI17", "url": "https://www.uniprot.org/uniprotkb/Q8NI17" }, { "database": "PubMed", "id": "15627637", "url": "https://pubmed.ncbi.nlm.nih.gov/15627637" }, { "database": "PubMed", "id": "15194700", "url": "https://pubmed.ncbi.nlm.nih.gov/15194700" } ], "uniprot_canonical_ac": "Q8NI17-1" }, { "start_pos": 670, "end_pos": 670, "sequence_org": "Y", "sequence_mut": "A", "comment": "No effect on STAT1 and STAT3 activation. Slight decrease; when associated with A-639 and A-708.", "evidence": [ { "database": "UniProtKB", "id": "Q8NI17", "url": "https://www.uniprot.org/uniprotkb/Q8NI17" }, { "database": "PubMed", "id": "15627637", "url": "https://pubmed.ncbi.nlm.nih.gov/15627637" }, { "database": "PubMed", "id": "15194700", "url": "https://pubmed.ncbi.nlm.nih.gov/15194700" } ], "uniprot_canonical_ac": "Q8NI17-1" }, { "start_pos": 670, "end_pos": 670, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on STAT3 and STAT5 activation. Mild effect on STAT1 activation.", "evidence": [ { "database": "UniProtKB", "id": "Q8NI17", "url": "https://www.uniprot.org/uniprotkb/Q8NI17" }, { "database": "PubMed", "id": "15627637", "url": "https://pubmed.ncbi.nlm.nih.gov/15627637" }, { "database": "PubMed", "id": "15194700", "url": "https://pubmed.ncbi.nlm.nih.gov/15194700" } ], "uniprot_canonical_ac": "Q8NI17-1" }, { "start_pos": 708, "end_pos": 708, "sequence_org": "Y", "sequence_mut": "A", "comment": "No effect on STAT1 and STAT3 activation. Slight decrease; when associated with A-639 and A-670.", "evidence": [ { "database": "UniProtKB", "id": "Q8NI17", "url": "https://www.uniprot.org/uniprotkb/Q8NI17" }, { "database": "PubMed", "id": "15627637", "url": "https://pubmed.ncbi.nlm.nih.gov/15627637" }, { "database": "PubMed", "id": "15194700", "url": "https://pubmed.ncbi.nlm.nih.gov/15194700" } ], "uniprot_canonical_ac": "Q8NI17-1" }, { "start_pos": 708, "end_pos": 708, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abrogates STAT3 activation. Loss of interaction with STAT3. Mild effect on STAT1 activation. 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"Interleukin 31 in vitiligo patients with and without pruritus.", "journal": "Acta dermatovenerologica Alpina, Pannonica, et Adriatica", "date": "2024-09", "authors": "Lashin Shaimaa E, Shaker Olfat G, El-Tahlawi Samar M, Yousef Esraa H, Yaseen Sara M", "reference": { "type": "PubMed", "id": "39324348", "url": "https://pubmed.ncbi.nlm.nih.gov/39324348" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6EBC2-1", "protein_name": "Interleukin-31", "gene_name": "IL31", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6EBC2", "url": "https://www.uniprot.org/uniprotkb/Q6EBC2" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.39324348", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ 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"reference": { "type": "PubMed", "id": "35595813", "url": "https://pubmed.ncbi.nlm.nih.gov/35595813" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q86SU0-1", "protein_name": "Immunoglobulin-like domain-containing receptor 1", "gene_name": "ILDR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15162-1", "protein_name": "Phospholipid scramblase 1", "gene_name": "PLSCR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9JJ00-1", "protein_name": "Phospholipid scramblase 1", "gene_name": "Plscr1", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q86SU0", "url": "https://www.uniprot.org/uniprotkb/Q86SU0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.35595813", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Imputation of SNPs associated with presbycusis through linkage disequilibrium analysis in the ILDR1 gene.", "journal": "Journal of genetics", "date": "2023", "authors": "Flores Sergio V, Levi-Monsalve Alejandro, Alvarez-Lobo Juan Pablo", "reference": { "type": "PubMed", "id": "36814109", "url": "https://pubmed.ncbi.nlm.nih.gov/36814109" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q86SU0-1", "protein_name": "Immunoglobulin-like domain-containing receptor 1", "gene_name": "ILDR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q86SU0", "url": "https://www.uniprot.org/uniprotkb/Q86SU0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36814109", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Born TL, Smith DE, Garka KE, Renshaw BR, Bertles JS, Sims JE", "reference": { "type": "PubMed", "id": "10882729", "url": "https://pubmed.ncbi.nlm.nih.gov/10882729" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WWZ1-1", "protein_name": "Interleukin-1 family member 10", "gene_name": "IL1F10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ERS7-1", "protein_name": "Interleukin-1 receptor-like 2", "gene_name": "Il1rl2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZN1-1", "protein_name": "Interleukin-1 receptor accessory protein-like 1", "gene_name": "IL1RAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP60-1", "protein_name": "X-linked interleukin-1 receptor accessory protein-like 2", "gene_name": "IL1RAPL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45983-1", "protein_name": "Mitogen-activated protein kinase 8", "gene_name": "MAPK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB29-1", "protein_name": "Interleukin-1 receptor-like 2", "gene_name": "IL1RL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ERS6-1", "protein_name": "X-linked interleukin-1 receptor accessory protein-like 2", "gene_name": "Il1rapl2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WWZ1", "url": "https://www.uniprot.org/uniprotkb/Q8WWZ1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10882729", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and characterization of IL1HY2, a novel interleukin-1 family member.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Lin H, Ho A S, Haley-Vicente D, Zhang J, Bernal-Fussell J, Pace A M, Hansen D, Schweighofer K, Mize N K, Ford J E", "reference": { "type": "PubMed", "id": "11278614", "url": "https://pubmed.ncbi.nlm.nih.gov/11278614" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WWZ1-1", "protein_name": "Interleukin-1 family member 10", "gene_name": "IL1F10", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WWZ1", "url": "https://www.uniprot.org/uniprotkb/Q8WWZ1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11278614", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2001", "authors": "Debets R, Timans JC, Homey B, Zurawski S, Sana TR, Lo S, Wagner J, Edwards G, Clifford T, Menon S, Bazan JF, Kastelein RA", "reference": { "type": "PubMed", "id": "11466363", "url": "https://pubmed.ncbi.nlm.nih.gov/11466363" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WWZ1-1", "protein_name": "Interleukin-1 family member 10", "gene_name": "IL1F10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZH8-1", "protein_name": "Interleukin-36 gamma", "gene_name": "IL36G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHA7-1", "protein_name": "Interleukin-36 alpha", "gene_name": "IL36A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9QYY1-1", "protein_name": "Interleukin-36 receptor antagonist protein", "gene_name": "Il36rn", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZH7-1", "protein_name": "Interleukin-36 beta", "gene_name": "IL36B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBH0-1", "protein_name": "Interleukin-36 receptor antagonist protein", "gene_name": "IL36RN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB29-1", "protein_name": "Interleukin-1 receptor-like 2", "gene_name": "IL1RL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9JLA2-1", "protein_name": "Interleukin-36 alpha", "gene_name": "Il36a", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WWZ1", "url": "https://www.uniprot.org/uniprotkb/Q8WWZ1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11466363", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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Interferon Cytokine Res.", "date": "2001", "authors": "Bensen J T, Dawson P A, Mychaleckyj J C, Bowden D W", "reference": { "type": "PubMed", "id": "11747621", "url": "https://pubmed.ncbi.nlm.nih.gov/11747621" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WWZ1-1", "protein_name": "Interleukin-1 family member 10", "gene_name": "IL1F10", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WWZ1", "url": "https://www.uniprot.org/uniprotkb/Q8WWZ1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11747621", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2012", "authors": "van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, van der Meer JW, Hao R, Kalabokis V, Dinarello CA", "reference": { "type": "PubMed", "id": "22315422", "url": "https://pubmed.ncbi.nlm.nih.gov/22315422" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WWZ1-1", "protein_name": "Interleukin-1 family member 10", "gene_name": "IL1F10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZH8-1", "protein_name": "Interleukin-36 gamma", "gene_name": "IL36G", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHA7-1", "protein_name": "Interleukin-36 alpha", "gene_name": "IL36A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZH7-1", "protein_name": "Interleukin-36 beta", "gene_name": "IL36B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZN1-1", "protein_name": "Interleukin-1 receptor accessory protein-like 1", "gene_name": "IL1RAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45983-1", "protein_name": "Mitogen-activated protein kinase 8", "gene_name": "MAPK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBH0-1", "protein_name": "Interleukin-36 receptor antagonist protein", "gene_name": "IL36RN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB29-1", "protein_name": "Interleukin-1 receptor-like 2", "gene_name": "IL1RL2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WWZ1", "url": "https://www.uniprot.org/uniprotkb/Q8WWZ1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22315422", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation and function of interleukin-36 cytokines in homeostasis and pathological conditions.", "journal": "Journal of leukocyte biology", "date": "2015", "authors": "Gabay C, Towne JE", "reference": { "type": "PubMed", "id": "25673295", "url": "https://pubmed.ncbi.nlm.nih.gov/25673295" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WWZ1-1", "protein_name": "Interleukin-1 family member 10", "gene_name": "IL1F10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZH8-1", "protein_name": "Interleukin-36 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"table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interleukin-38 is released from apoptotic cells to limit inflammatory macrophage responses.", "journal": "Journal of molecular cell biology", "date": "2016", "authors": "Mora J, Schlemmer A, Wittig I, Richter F, Putyrski M, Frank AC, Han Y, Jung M, Ernst A, Weigert A, Brune B", "reference": { "type": "PubMed", "id": "26892022", "url": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]