[ { "title": "miR-654-5p Targets GRAP to Promote Proliferation, Metastasis, and Chemoresistance of Oral Squamous Cell Carcinoma Through Ras/MAPK Signaling.", "journal": "DNA and cell biology", "date": "2018", "authors": "Lu M, Wang C, Chen W, Mao C, Wang J", "reference": { "type": "PubMed", "id": "29364705", "url": "https://pubmed.ncbi.nlm.nih.gov/29364705" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13588-1", "protein_name": "GRB2-related adapter protein", "gene_name": "GRAPL; GRAP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13588", "url": "https://www.uniprot.org/uniprotkb/Q13588" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29364705", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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Commun.", "date": "2001", "authors": "Ofman R, Lajmir S, Wanders RJ", "reference": { "type": "PubMed", "id": "11237722", "url": "https://pubmed.ncbi.nlm.nih.gov/11237722" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O15228-1", "protein_name": "Dihydroxyacetone phosphate acyltransferase", "gene_name": "GNPAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IAN0-1", "protein_name": "Peroxisomal reductase activating PPAR-gamma", "gene_name": "DHRS7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00116-1", "protein_name": "Alkyldihydroxyacetonephosphate synthase, peroxisomal", "gene_name": "AGPS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O15228", "url": "https://www.uniprot.org/uniprotkb/O15228" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11237722", "abstract": "", "glycosylation": 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Biophys. Res. Commun.", "date": "1997", "authors": "Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, O'Dowd BF", "reference": { "type": "PubMed", "id": "9344866", "url": "https://pubmed.ncbi.nlm.nih.gov/9344866" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O15529-1", "protein_name": "G protein-coupled receptor 42", "gene_name": "GPR42", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15552-1", "protein_name": "Free fatty acid receptor 2", "gene_name": "FFAR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14842-1", "protein_name": "Free fatty acid receptor 1", "gene_name": "FFAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14843-1", "protein_name": "Free fatty acid receptor 3", "gene_name": "FFAR3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O15529", "url": "https://www.uniprot.org/uniprotkb/O15529" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9344866", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human and mouse GPAA1 (glycosylphosphatidylinositol anchor attachment 1) genes: genomic structures, chromosome loci and the presence of a minor class intron.", "journal": "Cytogenet. 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit.", "journal": "Molecules (Basel, Switzerland)", "date": "2021", "authors": "Liu SS, Jin F, Liu YS, Murakami Y, Sugita Y, Kato T, Gao XD, Kinoshita T, Hattori M, Fujita M", "reference": { "type": "PubMed", "id": "34576938", "url": "https://pubmed.ncbi.nlm.nih.gov/34576938" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O43292-1", "protein_name": "GPI-anchor transamidase component GPAA1", "gene_name": "GPAA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92643-1", "protein_name": "GPI-anchor transamidase", "gene_name": "PIGK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96S52-1", "protein_name": "GPI-anchor transamidase component PIGS", "gene_name": "PIGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969N2-1", "protein_name": "GPI-anchor transamidase component PIGT", "gene_name": "PIGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H490-1", "protein_name": "GPI-anchor transamidase component PIGU", "gene_name": "PIGU", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": "https://www.uniprot.org/uniprotkb/O43292" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 137, "end_pos": 137, "sequence_org": "R", "sequence_mut": "A", "comment": "No effect on function in GPI-anchor attachment to protein.", "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": "https://www.uniprot.org/uniprotkb/O43292" }, { "database": "PubMed", "id": "34576938", "url": "https://pubmed.ncbi.nlm.nih.gov/34576938" } ], "uniprot_canonical_ac": "O43292-1" }, { "start_pos": 153, "end_pos": 153, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on function in GPI-anchor attachment to protein.", "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": "https://www.uniprot.org/uniprotkb/O43292" }, { "database": "PubMed", "id": "34576938", "url": "https://pubmed.ncbi.nlm.nih.gov/34576938" } ], "uniprot_canonical_ac": "O43292-1" }, { "start_pos": 186, "end_pos": 187, "sequence_org": "EH", "sequence_mut": "AA", "comment": "No effect on function in GPI-anchor attachment to protein.", "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": "https://www.uniprot.org/uniprotkb/O43292" }, { "database": "PubMed", "id": "34576938", "url": "https://pubmed.ncbi.nlm.nih.gov/34576938" } ], "uniprot_canonical_ac": "O43292-1" }, { "start_pos": 188, "end_pos": 188, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on function in GPI-anchor attachment to protein.", "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": "https://www.uniprot.org/uniprotkb/O43292" }, { "database": "PubMed", "id": "34576938", "url": "https://pubmed.ncbi.nlm.nih.gov/34576938" } ], "uniprot_canonical_ac": "O43292-1" }, { "start_pos": 203, "end_pos": 203, "sequence_org": "N", "sequence_mut": "Q", "comment": "No effect on function in GPI-anchor attachment to protein.", "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": 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"table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Loss of GPI-anchor attachment; when associated with Q-216.", "evidence": [ { "database": "UniProtKB", "id": "Q9BZM5", "url": "https://www.uniprot.org/uniprotkb/Q9BZM5" }, { "database": "PubMed", "id": "37684232", "url": "https://pubmed.ncbi.nlm.nih.gov/37684232" } ], "uniprot_canonical_ac": "Q9BZM5-1" } ], "record_id": "pubmed.37684232", "abstract": "", "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 3 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The affected gene underlying the class K glycosylphosphatidylinositol (GPI) surface protein defect codes for the GPI transamidase.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1997", "authors": "Yu J, Nagarajan S, Knez JJ, Udenfriend S, Chen R, Medof ME", "reference": { "type": "PubMed", "id": "9356492", "url": "https://pubmed.ncbi.nlm.nih.gov/9356492" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O43292-1", "protein_name": "GPI-anchor transamidase component GPAA1", "gene_name": "GPAA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92643-1", "protein_name": "GPI-anchor transamidase", "gene_name": "PIGK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96S52-1", "protein_name": "GPI-anchor transamidase component PIGS", "gene_name": "PIGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03405-1", "protein_name": "Urokinase plasminogen activator surface receptor", "gene_name": "PLAUR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969N2-1", "protein_name": "GPI-anchor transamidase component PIGT", "gene_name": "PIGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q75T13-1", "protein_name": "GPI inositol-deacylase", "gene_name": "PGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H490-1", "protein_name": "GPI-anchor transamidase component PIGU", "gene_name": "PIGU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9CXY9-1", "protein_name": "GPI-anchor transamidase", "gene_name": "Pigk", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O43292", "url": "https://www.uniprot.org/uniprotkb/O43292" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9356492", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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involved in G(s) protein activation.", "journal": "Molecular and cellular endocrinology", "date": "2002", "authors": "Timossi C, Maldonado D, Vizcaino A, Lindau-Shepard B, Conn PM, Ulloa-Aguirre A", "reference": { "type": "PubMed", "id": "12039074", "url": "https://pubmed.ncbi.nlm.nih.gov/12039074" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01148-1", "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P88-1", "protein_name": "Putative gonadotropin-releasing hormone II receptor", "gene_name": "GNRHR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16473-1", "protein_name": "Thyrotropin receptor", "gene_name": "TSHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22888-1", "protein_name": "Lutropin-choriogonadotropic hormone receptor", "gene_name": "LHCGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01229-1", "protein_name": "Lutropin subunit beta", "gene_name": "LHB", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor.", "journal": "The Journal of clinical investigation", "date": "2002", "authors": "Nakabayashi K, Matsumi H, Bhalla A, Bae J, Mosselman S, Hsu SY, Hsueh AJ", "reference": { "type": "PubMed", "id": "12045258", "url": "https://pubmed.ncbi.nlm.nih.gov/12045258" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01148-1", "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P88-1", "protein_name": "Putative gonadotropin-releasing hormone II receptor", "gene_name": "GNRHR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21463-1", "protein_name": "Thyrotropin receptor", "gene_name": "Tshr", "tax_name": "Rat" }, { 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor.", "journal": "Biochemical and biophysical research communications", "date": "1992", "authors": "Kakar SS, Musgrove LC, Devor DC, Sellers JC, Neill JD", "reference": { "type": "PubMed", "id": "1333190", "url": "https://pubmed.ncbi.nlm.nih.gov/1333190" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01148-1", "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "tax_name": 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Pharmacological characterization of a novel nonpeptide antagonist of the human gonadotropin-releasing hormone receptor, NBI-42902.", "journal": "Endocrinology", "date": "2007", "authors": "Struthers RS, Xie Q, Sullivan SK, Reinhart GJ, Kohout TA, Zhu YF, Chen C, Liu XJ, Ling N, Yang W, Maki RA, Bonneville AK, Chen TK, Bozigian HP", "reference": { "type": "PubMed", "id": "17095587", "url": "https://pubmed.ncbi.nlm.nih.gov/17095587" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01148-1", "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P88-1", "protein_name": "Putative gonadotropin-releasing hormone II receptor", "gene_name": "GNRHR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16473-1", "protein_name": "Thyrotropin receptor", "gene_name": "TSHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22888-1", "protein_name": "Lutropin-choriogonadotropic hormone receptor", "gene_name": "LHCGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01229-1", "protein_name": "Lutropin subunit 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"protein_name": "Gonadotropin-releasing hormone receptor", "gene_name": "GNRHR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01148", "url": "https://www.uniprot.org/uniprotkb/P01148" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17095587", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Discovery of 1-4-[1-(2,6-difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl]phenyl-3-methoxyurea (TAK-385) as a potent, orally active, non-peptide antagonist of the human gonadotropin-releasing hormone receptor.", "journal": "Journal of medicinal chemistry", "date": "2011", "authors": "Miwa K, Hitaka T, Imada T, Sasaki S, Yoshimatsu M, Kusaka M, Tanaka A, Nakata D, Furuya S, Endo S, Hamamura K, Kitazaki T", "reference": { "type": "PubMed", "id": "21657270", "url": "https://pubmed.ncbi.nlm.nih.gov/21657270" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01148-1", "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P88-1", "protein_name": "Putative gonadotropin-releasing hormone II receptor", "gene_name": "GNRHR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16473-1", "protein_name": "Thyrotropin receptor", "gene_name": "TSHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22888-1", "protein_name": "Lutropin-choriogonadotropic hormone receptor", "gene_name": "LHCGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01229-1", "protein_name": "Lutropin subunit beta", "gene_name": "LHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YW7-1", "protein_name": "Glycoprotein hormone beta-5", "gene_name": "GPHB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43555-1", "protein_name": "Progonadoliberin-2", "gene_name": "GNRH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T91-1", "protein_name": "Glycoprotein hormone alpha-2", "gene_name": "GPHA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23945-1", "protein_name": "Follicle-stimulating hormone receptor", "gene_name": "FSHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01215-1", "protein_name": "Glycoprotein hormones alpha chain", "gene_name": "CGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01225-1", "protein_name": "Follitropin subunit beta", "gene_name": "FSHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01222-1", "protein_name": "Thyrotropin subunit beta", "gene_name": "TSHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30968-1", "protein_name": "Gonadotropin-releasing hormone receptor", "gene_name": "GNRHR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ 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"Cloning and sequencing of human LH/hCG receptor cDNA.", "journal": "Biochemical and biophysical research communications", "date": "1990", "authors": "Minegishi T, Nakamura K, Takakura Y, Miyamoto K, Hasegawa Y, Ibuki Y, Igarashi M, Minegish T [corrected to Minegishi T]", "reference": { "type": "PubMed", "id": "2244890", "url": "https://pubmed.ncbi.nlm.nih.gov/2244890" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P01148-1", "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P88-1", "protein_name": "Putative gonadotropin-releasing hormone II receptor", "gene_name": "GNRHR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16473-1", "protein_name": "Thyrotropin receptor", "gene_name": "TSHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22888-1", "protein_name": "Lutropin-choriogonadotropic hormone receptor", "gene_name": "LHCGR", "tax_name": "Human" }, { "uniprot_canonical_ac": 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}, { "uniprot_canonical_ac": "P30968-1", "protein_name": "Gonadotropin-releasing hormone receptor", "gene_name": "GNRHR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01148", "url": "https://www.uniprot.org/uniprotkb/P01148" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2244890", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"Follitropin subunit beta", "gene_name": "FSHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01222-1", "protein_name": "Thyrotropin subunit beta", "gene_name": "TSHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30968-1", "protein_name": "Gonadotropin-releasing hormone receptor", "gene_name": "GNRHR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P01148", "url": "https://www.uniprot.org/uniprotkb/P01148" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2558651", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { 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Biol. 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Genet.", "date": "1991", "authors": "Kondoh T, Kanno H, Chang LF, Yoshida A", "reference": { "type": "PubMed", "id": "1757097", "url": "https://pubmed.ncbi.nlm.nih.gov/1757097" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P36959-1", "protein_name": "GMP reductase 1", "gene_name": "GMPR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P36959", "url": "https://www.uniprot.org/uniprotkb/P36959" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1757097", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion.", "journal": "Cell reports", "date": "2013", "authors": "Wawrzyniak JA, Bianchi-Smiraglia A, Bshara W, Mannava S, Ackroyd J, Bagati A, Omilian AR, Im M, Fedtsova N, Miecznikowski JC, Moparthy KC, Zucker SN, Zhu Q, Kozlova NI, Berman AE, Hoek KS, Gudkov AV, Shewach DS, Morrison CD, Nikiforov MA", "reference": { "type": "PubMed", "id": "24139804", "url": "https://pubmed.ncbi.nlm.nih.gov/24139804" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two structural genes on different chromosomes are required for encoding the major subunit of human red cell glucose-6-phosphate dehydrogenase.", "journal": "Cell", "date": "1989", "authors": "Kanno H, Huang I Y, Kan Y W, Yoshida A", "reference": { "type": "PubMed", "id": "2758468", "url": "https://pubmed.ncbi.nlm.nih.gov/2758468" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P36959-1", "protein_name": "GMP reductase 1", "gene_name": "GMPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11413-1", "protein_name": "Glucose-6-phosphate 1-dehydrogenase", "gene_name": "G6PD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P36959", "url": "https://www.uniprot.org/uniprotkb/P36959" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "snv": [ { "evidence": [ { "id": "rs137852338", "database": "dbSNP", "url": 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"description": "" }, { "id": "DOID:2861", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2861", "name": "congenital nonspherocytic hemolytic anaemia", "description": "" }, { "id": "DOID:2861", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2861", "name": "hereditary nonspherocytic hemolytic anaemia", "description": "" }, { "id": "DOID:2861", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2861", "name": "hereditary nonspherocytic hemolytic anemia", "description": "" }, { "id": "MONDO:0008789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008789", "name": "anemia, nonspherocytic hemolytic, associated with abnormality of red cell membrane", "description": "" }, { "id": "MONDO:0008789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008789", "name": "anemia, nonspherocytic hemolytic, associated with abnormality of red cell membrane", 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Individuals with hemizygous or homozygous G6PD variants associated with chronic nonspherocytic hemolytic anemia (CNSHA) will clinically manifest CNSHA. 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patients with isolated dystonia reveals a novel mutation with partial loss of function.", "journal": "Journal of neurology", "date": "2016", "authors": "Dos Santos CO, Masuho I, da Silva-Junior FP, Barbosa ER, Silva SM, Borges V, Ferraz HB, Rocha MS, Limongi JC, Martemyanov KA, de Carvalho Aguiar P", "reference": { "type": "PubMed", "id": "26810727", "url": "https://pubmed.ncbi.nlm.nih.gov/26810727" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P38405-1", "protein_name": "Guanine nucleotide-binding protein G(olf) subunit alpha", "gene_name": "GNAL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P38405", "url": "https://www.uniprot.org/uniprotkb/P38405" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26810727", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], 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