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    },
    {
        "title": "Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper.",
        "journal": "Molecular cell",
        "date": "2015-08-20",
        "authors": "Webster Alexandre, Li Sisi, Hur Junho K, Wachsmuth Malte, Bois Justin S, Perkins Edward M, Patel Dinshaw J, Aravin Alexei A",
        "reference": {
            "type": "PubMed",
            "id": "26295961",
            "url": "https://pubmed.ncbi.nlm.nih.gov/26295961"
        },
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            {
                "uniprot_canonical_ac": "O76922-1",
                "protein_name": "Protein aubergine",
                "gene_name": "aub",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "P25823-1",
                "protein_name": "Protein tudor",
                "gene_name": "tud",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "A1ZAC4-1",
                "protein_name": "Tudor domain-containing protein krimp",
                "gene_name": "krimp",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "P09052-1",
                "protein_name": "ATP-dependent RNA helicase vasa",
                "gene_name": "vas",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "Q9VKD7-1",
                "protein_name": "Mitochondrial cardiolipin hydrolase",
                "gene_name": "zuc",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "Q7PLK0-1",
                "protein_name": "Protein argonaute-3",
                "gene_name": "AGO3",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "Q9VF26-1",
                "protein_name": "Probable ATP-dependent RNA helicase spindle-E",
                "gene_name": "spn-E",
                "tax_name": "Fruit fly"
            }
        ],
        "species": [
            {
                "name": "Drosophila melanogaster",
                "taxid": 7227,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "O76922",
                        "url": "https://www.uniprot.org/uniprotkb/O76922"
                    }
                ],
                "common_name": "Fruit fly",
                "glygen_name": "Fruit fly",
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            }
        ],
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            {
                "start_pos": 11,
                "end_pos": 26,
                "sequence_org": "RGRGRGRKPNNVEANR",
                "sequence_mut": "KGKGKGKKPNNVEANK",
                "comment": "Lacks symmetric dimethylated arginine modification but does not affect ability to recruit csul/PRMT5. Abrogates interaction with krimp and tud. No effect on slicer activity. Recruited to nuage but is less stably associated than wild-type and more readily diffuses into the cytosol. Fails to localize to the pole plasm. Unable to rescue transposon derepression and sterility phenotypes in a mutant model.",
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "O76922",
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                    {
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                ],
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            },
            {
                "start_pos": 568,
                "end_pos": 572,
                "sequence_org": "YSCIK",
                "sequence_mut": "LSCIE",
                "comment": "Abrogates piRNA binding. Prevents recruitment of csul/PRMT5 and reduces the level of symmetrical methylation of arginine PTM. Prevents localization to the nuage. Does not affect binding to krimp. Abrogates interaction with tud. Fails to localize to the pole plasm.",
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                    {
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                    },
                    {
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                        "id": "34210982",
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                ],
                "uniprot_canonical_ac": "O76922-1"
            },
            {
                "start_pos": 579,
                "end_pos": 583,
                "sequence_org": "YAAIK",
                "sequence_mut": "LAAIE",
                "comment": "Abrogates piRNA binding. Does not affect binding to krimp. Reduces mobility within the nuage, probably due to association with krimp.",
                "evidence": [
                    {
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                        "id": "Q7PLK0",
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                        "id": "26295961",
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            },
            {
                "start_pos": 68,
                "end_pos": 72,
                "sequence_org": "RGRAR",
                "sequence_mut": "KGKAK",
                "comment": "Abolishes binding to papi. Does not affect binding to krimp.",
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                    {
                        "database": "UniProtKB",
                        "id": "Q7PLK0",
                        "url": "https://www.uniprot.org/uniprotkb/Q7PLK0"
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                    {
                        "database": "PubMed",
                        "id": "21447556",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/21447556"
                    },
                    {
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                        "id": "26295961",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/26295961"
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        ],
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        ]
    },
    {
        "title": "An in vivo proteomic analysis of the Me31B interactome in Drosophila germ granules.",
        "journal": "FEBS Lett.",
        "date": "2017",
        "authors": "DeHaan H, McCambridge A, Armstrong B, Cruse C, Solanki D, Trinidad JC, Arkov AL, Gao M",
        "reference": {
            "type": "PubMed",
            "id": "28945271",
            "url": "https://pubmed.ncbi.nlm.nih.gov/28945271"
        },
        "referenced_glycans": [],
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            {
                "uniprot_canonical_ac": "O76922-1",
                "protein_name": "Protein aubergine",
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                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "P25823-1",
                "protein_name": "Protein tudor",
                "gene_name": "tud",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "P23128-1",
                "protein_name": "ATP-dependent RNA helicase me31b",
                "gene_name": "me31B",
                "tax_name": "Fruit fly"
            },
            {
                "uniprot_canonical_ac": "P09052-1",
                "protein_name": "ATP-dependent RNA helicase vasa",
                "gene_name": "vas",
                "tax_name": "Fruit fly"
            }
        ],
        "species": [
            {
                "name": "Drosophila melanogaster",
                "taxid": 7227,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "O76922",
                        "url": "https://www.uniprot.org/uniprotkb/O76922"
                    }
                ],
                "common_name": "Fruit fly",
                "glygen_name": "Fruit fly",
                "reference_species": "Drosophila melanogaster [7227]"
            }
        ],
        "record_id": "pubmed.28945271",
        "abstract": "",
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                "table_id": "referenced_proteins",
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    },
    {
        "title": "Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex.",
        "journal": "Nature communications",
        "date": "2021-07-01",
        "authors": "Huang Xiawei, Hu Hongmiao, Webster Alexandre, Zou Fan, Du Jiamu, Patel Dinshaw J, Sachidanandam Ravi, Toth Katalin Fejes, Aravin Alexei A, Li Sisi",
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                "name": "Drosophila melanogaster",
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    {
        "title": "aubergine enhances oskar translation in the Drosophila ovary.",
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        "authors": "Wilson J E, Connell J E, Macdonald P M",
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    {
        "title": "A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9 in Drosophila melanogaster.",
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]
