[ { "title": "Very long-chain acyl-CoA synthetases. Human `bubblegum` represents a new family of proteins capable of activating very long-chain fatty acids.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Steinberg SJ, Morgenthaler J, Heinzer AK, Smith KD, Watkins PA", "reference": { "type": "PubMed", "id": "10954726", "url": "https://pubmed.ncbi.nlm.nih.gov/10954726" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10954726", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol.", "journal": "Biochemical and biophysical research communications", "date": "2001", "authors": "Bene H, Lasky D, Ntambi JM", "reference": { "type": "PubMed", "id": "11414710", "url": "https://pubmed.ncbi.nlm.nih.gov/11414710" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5C1-1", "protein_name": "Angiopoietin-related protein 3", "gene_name": "ANGPTL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28702-1", "protein_name": "Retinoic acid receptor RXR-beta", "gene_name": "RXRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13133-1", "protein_name": "Oxysterols receptor LXR-alpha", "gene_name": "NR1H3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11414710", "abstract": "", "glycosylation": [], 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation.", "journal": "Nature genetics", "date": "2002", "authors": "Meloni I, Muscettola M, Raynaud M, Longo I, Bruttini M, Moizard MP, Gomot M, Chelly J, des Portes V, Fryns JP, Ropers HH, Magi B, Bellan C, Volpi N, Yntema HG, Lewis SE, Schaffer JE, Renieri A", "reference": { "type": "PubMed", "id": "11889465", "url": "https://pubmed.ncbi.nlm.nih.gov/11889465" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11889465", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SREBP-2 and NF-Y are involved in the transcriptional regulation of squalene epoxidase.", "journal": "Biochemical and biophysical research communications", "date": "2002", "authors": "Nagai M, Sakakibara J, Nakamura Y, Gejyo F, Ono T", "reference": { "type": "PubMed", "id": "12083769", "url": "https://pubmed.ncbi.nlm.nih.gov/12083769" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor 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"gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52020-1", "protein_name": "Squalene monooxygenase", "gene_name": "Sqle", "tax_name": "Rat" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"Amemiya-Kudo M, Shimano H, Hasty AH, Yahagi N, Yoshikawa T, Matsuzaka T, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Sato R, Kimura S, Ishibashi S, Yamada N", "reference": { "type": "PubMed", "id": "12177166", "url": "https://pubmed.ncbi.nlm.nih.gov/12177166" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96G25-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "MED8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY76-1", "protein_name": "Angiopoietin-related protein 4", "gene_name": "ANGPTL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A9YTQ3-1", "protein_name": "Aryl hydrocarbon receptor repressor", "gene_name": "AHRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35869-1", "protein_name": "Aryl hydrocarbon receptor", "gene_name": "AHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27540-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator", "gene_name": "ARNT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU7-1", "protein_name": "Tribbles homolog 3", "gene_name": "TRIB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBZ2-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator 2", "gene_name": "ARNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H204-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 28", "gene_name": "MED28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15327-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "ANKRD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14192-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50416-1", "protein_name": "Carnitine O-palmitoyltransferase 1, liver isoform", "gene_name": "CPT1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71SY5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "MED25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16881-1", "protein_name": "Thioredoxin reductase 1, cytoplasmic", "gene_name": "TXNRD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23786-1", "protein_name": "Carnitine O-palmitoyltransferase 2, mitochondrial", "gene_name": "CPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22680-1", "protein_name": "Cytochrome P450 7A1", "gene_name": "CYP7A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54868-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, mitochondrial", "gene_name": "HMGCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUE0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "MED18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 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"uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q9-1", "protein_name": "Nuclear receptor coactivator 3", "gene_name": "NCOA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13227-1", "protein_name": "G protein pathway suppressor 2", "gene_name": "GPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28702-1", "protein_name": "Retinoic acid receptor RXR-beta", "gene_name": "RXRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": 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"protein_name": "Phosphatidylcholine translocator ABCB4", "gene_name": "ABCB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0JLT2-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 19", "gene_name": "MED19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15528-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "MED22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTT4-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 10", "gene_name": "MED10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2W1-1", "protein_name": "Thyroid hormone receptor-associated protein 3", "gene_name": "THRAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36956-1", "protein_name": "Sterol regulatory element-binding protein 1", "gene_name": "SREBF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06520-1", "protein_name": "Sulfotransferase 2A1", "gene_name": "SULT2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75586-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 6", "gene_name": "MED6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27469-1", "protein_name": "G0/G1 switch protein 2", "gene_name": "G0S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZI5-1", "protein_name": "Grainyhead-like protein 1 homolog", "gene_name": "GRHL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48163-1", "protein_name": "NADP-dependent malic enzyme", "gene_name": "ME1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43513-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 7", "gene_name": "MED7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07148-1", "protein_name": "Fatty acid-binding protein, liver", "gene_name": "FABP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13133-1", "protein_name": "Oxysterols receptor LXR-alpha", "gene_name": "NR1H3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01019-1", "protein_name": "Angiotensinogen", "gene_name": "AGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15379-1", "protein_name": "Histone deacetylase 3", "gene_name": "HDAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02652-1", "protein_name": "Apolipoprotein A-II", "gene_name": "APOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPJ6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 4", "gene_name": "MED4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20393-1", "protein_name": "Nuclear receptor subfamily 1 group D member 1", "gene_name": "NR1D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Q788-1", "protein_name": "Apolipoprotein A-V", "gene_name": "APOA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3C7-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 31", "gene_name": "MED31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60656-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "UGT1A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13196-1", "protein_name": "5-aminolevulinate synthase, non-specific, mitochondrial", "gene_name": "ALAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99743-1", "protein_name": "Neuronal PAS domain-containing protein 2", "gene_name": "NPAS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00327-2", "protein_name": "Basic helix-loop-helix ARNT-like protein 1", "gene_name": "BMAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15516-1", "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "CLOCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04798-1", "protein_name": "Cytochrome P450 1A1", "gene_name": "CYP1A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RI1-3", "protein_name": "Bile acid receptor", "gene_name": "NR1H4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99541-1", "protein_name": "Perilipin-2", "gene_name": "PLIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75192-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YN6-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-beta", "gene_name": "PPARGC1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RN5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "gene_name": "MED15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EK7-1", "protein_name": "Constitutive coactivator of peroxisome proliferator-activated receptor gamma", "gene_name": "FAM120B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZL6-1", "protein_name": "Ral guanine nucleotide dissociation stimulator-like 1", "gene_name": "RGL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVF5-1", "protein_name": "Rho guanine nucleotide exchange factor TIAM2", "gene_name": "TIAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75509-1", "protein_name": "Tumor necrosis factor receptor superfamily member 21", "gene_name": "TNFRSF21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24863-1", "protein_name": "Cyclin-C", "gene_name": "CCNC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49336-1", "protein_name": "Cyclin-dependent kinase 8", "gene_name": "CDK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16656-1", "protein_name": "Nuclear respiratory factor 1", "gene_name": "NRF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13503-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 21", "gene_name": "MED21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BWU1-1", "protein_name": "Cyclin-dependent kinase 19", "gene_name": "CDK19", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95402-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 26", "gene_name": "MED26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HR3-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 30", "gene_name": "MED30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11474-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "ESRRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60427-1", "protein_name": "Acyl-CoA (8-3)-desaturase", "gene_name": "FADS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48060-1", "protein_name": "Glioma pathogenesis-related protein 1", "gene_name": "GLIPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95477-1", "protein_name": "Phospholipid-transporting ATPase ABCA1", "gene_name": "ABCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02647-1", "protein_name": "Apolipoprotein A-I", "gene_name": "APOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93074-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 12", "gene_name": "MED12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11310-1", "protein_name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "ACADM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 342, "end_pos": 342, "sequence_org": "Y", "sequence_mut": "R", "comment": "Abolished transactivation activity.", "evidence": [ { "database": "UniProtKB", "id": "Q12772", "url": "https://www.uniprot.org/uniprotkb/Q12772" }, { "database": "PubMed", "id": "12177166", "url": "https://pubmed.ncbi.nlm.nih.gov/12177166" } ], "uniprot_canonical_ac": "Q12772-1" }, { "start_pos": 335, "end_pos": 335, "sequence_org": "Y", "sequence_mut": "R", "comment": "Abolished transactivation activity.", "evidence": [ { "database": "UniProtKB", "id": "P36956", "url": "https://www.uniprot.org/uniprotkb/P36956" }, { "database": "PubMed", "id": "12177166", "url": "https://pubmed.ncbi.nlm.nih.gov/12177166" } ], "uniprot_canonical_ac": "P36956-1" } ], "record_id": "pubmed.12177166", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 133 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and expression of mammalian long-chain PUFA elongation enzymes.", "journal": "Lipids", "date": "2002", "authors": "Leonard AE, Kelder B, Bobik EG, Chuang LT, Lewis CJ, Kopchick JJ, Mukerji P, Huang YS", "reference": { "type": "PubMed", "id": "12371743", "url": "https://pubmed.ncbi.nlm.nih.gov/12371743" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", 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"gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport 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ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12371743", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Moon YA, Horton JD", "reference": { "type": "PubMed", "id": "12482854", "url": "https://pubmed.ncbi.nlm.nih.gov/12482854" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9CY27-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "Tecr", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O70503-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "Hsd17b12", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12482854", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12525535", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", 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"tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": 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"uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12764144", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", 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elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12975357", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BWD1-1", "protein_name": "Acetyl-CoA acetyltransferase, cytosolic", "gene_name": "ACAT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXS1-1", "protein_name": "Isopentenyl-diphosphate delta-isomerase 2", "gene_name": "IDI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY26-1", "protein_name": "Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6", "gene_name": "PLPP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1377680", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Pei Z, Fraisl P, Berger J, Jia Z, Forss-Petter S, Watkins PA", "reference": { "type": "PubMed", "id": "15469937", "url": "https://pubmed.ncbi.nlm.nih.gov/15469937" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O88561-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "Slc27a3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15469937", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Grayson C, Molday RS", "reference": { "type": "PubMed", "id": "16036915", "url": "https://pubmed.ncbi.nlm.nih.gov/16036915" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 20, "start_aa": "Asn", "end_pos": 20, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn20", "evidence": [ { "id": "Q9GZR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9GZR5#ptm_processing" }, { "id": "MF_03204", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/MF_03204" }, { "id": "16036915", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/16036915" } ], "filter_code": "001000000000000000000.00010000000000.00.01001", "uniprot_canonical_ac": "Q9GZR5-1" } ], "record_id": 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"journal": "Journal of lipid research", "date": "2007", "authors": "Fujimoto Y, Itabe H, Kinoshita T, Homma KJ, Onoduka J, Mori M, Yamaguchi S, Makita M, Higashi Y, Yamashita A, Takano T", "reference": { "type": "PubMed", "id": "17379924", "url": "https://pubmed.ncbi.nlm.nih.gov/17379924" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid 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"Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17379924", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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nutrition", "date": "2007", "authors": "Shin ES, Lee HH, Cho SY, Park HW, Lee SJ, Lee TR", "reference": { "type": "PubMed", "id": "17449569", "url": "https://pubmed.ncbi.nlm.nih.gov/17449569" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15503-1", "protein_name": "Insulin-induced gene 1 protein", "gene_name": "INSIG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": 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"protein_name": "Acyl-CoA-binding domain-containing protein 7", "gene_name": "ACBD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C7M7-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "ACSM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1Q8-1", "protein_name": "Acyl-coenzyme A thioesterase THEM5", "gene_name": "THEM5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y305-1", "protein_name": "Acyl-coenzyme A thioesterase 9, mitochondrial", "gene_name": "ACOT9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H6R3-1", "protein_name": "Acyl-CoA synthetase short-chain family member 3, mitochondrial", "gene_name": "ACSS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IQU4-1", "protein_name": "Protein CWC15 homolog", "gene_name": "acsl4b; cwc15", "tax_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02338-1", "protein_name": "D-beta-hydroxybutyrate dehydrogenase, mitochondrial", "gene_name": "BDH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZUV0-1", "protein_name": "Cytosolic acyl coenzyme A thioester hydrolase-like", "gene_name": "ACOT7L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5RG49-1", "protein_name": "Beta-alanine-activating enzyme", "gene_name": "aasdh", "tax_name": "Zebrafish" }, { "uniprot_canonical_ac": "P42765-1", "protein_name": "3-ketoacyl-CoA thiolase, mitochondrial", "gene_name": "ACAA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49753-1", "protein_name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "gene_name": "ACOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TX2-1", "protein_name": "Acyl-coenzyme A thioesterase 1", "gene_name": "ACOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86V21-1", "protein_name": "Acetoacetyl-CoA synthetase", "gene_name": "AACS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPJ3-1", "protein_name": "Acyl-coenzyme A thioesterase 13", "gene_name": "ACOT13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXI4-1", "protein_name": "Acyl-coenzyme A thioesterase 11", "gene_name": "ACOT11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WYK0-1", "protein_name": "Acetyl-coenzyme A thioesterase", "gene_name": "ACOT12", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17762044", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 61 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Villagra A, Ulloa N, Zhang X, Yuan Z, Sotomayor E, Seto E", "reference": { "type": "PubMed", "id": "17925399", "url": "https://pubmed.ncbi.nlm.nih.gov/17925399" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17925399", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Yao H, Ye J", "reference": { "type": "PubMed", "id": "18003621", "url": "https://pubmed.ncbi.nlm.nih.gov/18003621" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": 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"record_id": "pubmed.18003621", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], 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Sakuraba H, Mizutani Y, Igarashi Y, Kihara A", "reference": { "type": "PubMed", "id": "18554506", "url": "https://pubmed.ncbi.nlm.nih.gov/18554506" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", 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"uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18654640", "abstract": "", "glycosylation": [], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN).", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Choi WI, Jeon BN, Park H, Yoo JY, Kim YS, Koh DI, Kim MH, Kim YR, Lee CE, Kim KS, Osborne TF, Hur MW", "reference": { "type": "PubMed", "id": "18682402", "url": "https://pubmed.ncbi.nlm.nih.gov/18682402" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18682402", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "cDNA cloning, chromosome mapping and expression characterization of human geranylgeranyl pyrophosphate synthase.", "journal": "Science in China. Series C, Life sciences", "date": "2000", "authors": "Zhao Y, Yu L, Gao J, Fu Q, Hua Y, Zhang H, Zhao S", "reference": { "type": "PubMed", "id": "18726356", "url": "https://pubmed.ncbi.nlm.nih.gov/18726356" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18726356", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Agbaga MP, Brush RS, Mandal MN, Henry K, Elliott MH, Anderson RE", "reference": { "type": "PubMed", "id": "18728184", "url": "https://pubmed.ncbi.nlm.nih.gov/18728184" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9EQC4-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "Elovl4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18728184", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Elovl6: a new player in fatty acid metabolism and insulin sensitivity.", "journal": "Journal of molecular medicine (Berlin, Germany)", "date": "2009", "authors": "Matsuzaka T, Shimano H", "reference": { "type": "PubMed", "id": "19259639", "url": "https://pubmed.ncbi.nlm.nih.gov/19259639" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19259639", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and characterization of a selective radioligand for ELOVL6.", "journal": "Journal of biochemistry", "date": "2009", "authors": "Shimamura K, Takahashi H, Kitazawa H, Miyamoto Y, Nagumo A, Tang C, Dean D, Nagase T, Sato N, Tokita S", "reference": { "type": "PubMed", "id": "19505953", "url": "https://pubmed.ncbi.nlm.nih.gov/19505953" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19505953", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Development of a high-density assay for long-chain fatty acyl-CoA elongases.", "journal": "Lipids", "date": "2009-08", "authors": "Kitazawa Hidefumi, Miyamoto Yasuhisa, Shimamura Ken, Nagumo Akira, Tokita Shigeru", "reference": { "type": "PubMed", "id": "19575253", "url": "https://pubmed.ncbi.nlm.nih.gov/19575253" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19575253", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Isolation and sequence of the human farnesyl pyrophosphate synthetase cDNA. Coordinate regulation of the mRNAs for farnesyl pyrophosphate synthetase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and 3-hydroxy-3-methylglutaryl coenzyme A synthase by phorbol ester.", "journal": "The Journal of biological chemistry", "date": "1990", "authors": "Wilkin DJ, Kutsunai SY, Edwards PA", "reference": { "type": "PubMed", "id": "1968462", "url": "https://pubmed.ncbi.nlm.nih.gov/1968462" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1968462", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.", "journal": "Cancer research", "date": "2009", "authors": "Tamura K, Makino A, Hullin-Matsuda F, Kobayashi T, Furihata M, Chung S, Ashida S, Miki T, Fujioka T, Shuin T, Nakamura Y, Nakagawa H", "reference": { "type": "PubMed", "id": "19826053", "url": "https://pubmed.ncbi.nlm.nih.gov/19826053" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19826053", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box.", "journal": "Biochimica et biophysica acta", "date": "2010", "authors": "Schiavoni G, Bennati AM, Castelli M, Della Fazia MA, Beccari T, Servillo G, Roberti R", "reference": { "type": "PubMed", "id": "20138239", "url": "https://pubmed.ncbi.nlm.nih.gov/20138239" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": 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}, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.", "journal": "Human molecular genetics", "date": "2010", "authors": "Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP", "reference": { "type": "PubMed", "id": "20332099", "url": "https://pubmed.ncbi.nlm.nih.gov/20332099" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRP0-1", "protein_name": "Oligosaccharyltransferase complex subunit OSTC", "gene_name": "OSTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YA3-1", 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nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells.", "journal": "The Biochemical journal", "date": "2010", "authors": "Ishimoto K, Tachibana K, Hanano I, Yamasaki D, Nakamura H, Kawai M, Urano Y, Tanaka T, Hamakubo T, Sakai J, Kodama T, Doi T", "reference": { "type": "PubMed", "id": "20450493", "url": "https://pubmed.ncbi.nlm.nih.gov/20450493" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing 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"uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis.", "journal": "Journal of lipid research", "date": "2010", "authors": "Lu B, Jiang YJ, Kim P, Moser A, Elias PM, Grunfeld C, Feingold KR", "reference": { "type": "PubMed", "id": "20719759", "url": "https://pubmed.ncbi.nlm.nih.gov/20719759" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", 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"protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20719759", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2010", "authors": "Ohno Y, Suto S, Yamanaka M, Mizutani Y, Mitsutake S, Igarashi Y, Sassa T, Kihara A", "reference": { "type": "PubMed", "id": "20937905", "url": "https://pubmed.ncbi.nlm.nih.gov/20937905" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96G23-1", "protein_name": "Ceramide synthase 2", "gene_name": "CERS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9JLJ5-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "Elovl1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Biochemical characterization of the very long-chain fatty acid elongase ELOVL7.", "journal": "FEBS letters", "date": "2011", "authors": "Naganuma T, Sato Y, Sassa T, Ohno Y, Kihara A", "reference": { "type": "PubMed", "id": "21959040", "url": "https://pubmed.ncbi.nlm.nih.gov/21959040" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 150, "end_pos": 150, "sequence_org": "H", "sequence_mut": "A", "comment": "Loss of activity alone or when associated with A-151.", "evidence": [ { "database": "UniProtKB", "id": "A1L3X0", "url": "https://www.uniprot.org/uniprotkb/A1L3X0" }, { "database": "PubMed", "id": "21959040", "url": "https://pubmed.ncbi.nlm.nih.gov/21959040" }, { "database": "PubMed", "id": "34117479", "url": "https://pubmed.ncbi.nlm.nih.gov/34117479" } ], "uniprot_canonical_ac": "A1L3X0-1" }, { "start_pos": 151, "end_pos": 151, "sequence_org": "H", "sequence_mut": "A", "comment": "Loss of activity; when associated with A-150.", "evidence": [ { "database": "UniProtKB", "id": "A1L3X0", "url": "https://www.uniprot.org/uniprotkb/A1L3X0" }, { "database": "PubMed", "id": "21959040", "url": "https://pubmed.ncbi.nlm.nih.gov/21959040" } ], "uniprot_canonical_ac": "A1L3X0-1" } ], "record_id": "pubmed.21959040", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and functional characterization of human glycerol-3-phosphate acyltransferase 1 gene promoters.", "journal": "Biochemical and biophysical research communications", "date": "2012", "authors": "Harada N, Fujimoto E, Okuyama M, Sakaue H, Nakaya Y", "reference": { "type": "PubMed", "id": "22634312", "url": "https://pubmed.ncbi.nlm.nih.gov/22634312" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22634312", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"uniprot_canonical_ac": "Q9NV23-1", "protein_name": "S-acyl fatty acid synthase thioesterase, medium chain", "gene_name": "OLAH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SK9-1", "protein_name": "Stearoyl-CoA desaturase 5", "gene_name": "SCD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N4T8-1", "protein_name": "3-oxoacyl-[acyl-carrier-protein] reductase", "gene_name": "CBR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X9-1", "protein_name": "ATPase MORC2", "gene_name": "MORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMR5-1", "protein_name": "Lysosomal thioesterase PPT2", "gene_name": "PPT2-EGFL8; PPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14975-1", "protein_name": "Long-chain fatty acid transport protein 2", "gene_name": "SLC27A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P86397-1", "protein_name": "Hydroxyacyl-thioester dehydratase type 2, mitochondrial", "gene_name": "HTD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53396-1", "protein_name": "ATP-citrate synthase", "gene_name": "ACLY", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7567999", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 50 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Bennett MK, Lopez JM, Sanchez HB, Osborne TF", "reference": { "type": "PubMed", "id": "7592729", "url": "https://pubmed.ncbi.nlm.nih.gov/7592729" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7592729", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1995", "authors": "Abu-Elheiga L, Jayakumar A, Baldini A, Chirala SS, Wakil SJ", "reference": { "type": "PubMed", "id": "7732023", "url": "https://pubmed.ncbi.nlm.nih.gov/7732023" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5EBL8-1", "protein_name": "PDZ domain-containing protein 11", "gene_name": "PDZD11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92506-1", "protein_name": "(3R)-3-hydroxyacyl-CoA dehydrogenase", "gene_name": "HSD17B8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50897-1", "protein_name": "Palmitoyl-protein thioesterase 1", "gene_name": "PPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NV23-1", "protein_name": "S-acyl fatty acid synthase thioesterase, medium chain", "gene_name": "OLAH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SK9-1", "protein_name": "Stearoyl-CoA desaturase 5", "gene_name": "SCD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y289-1", "protein_name": "Sodium-dependent multivitamin transporter", "gene_name": "SLC5A6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N4T8-1", "protein_name": "3-oxoacyl-[acyl-carrier-protein] reductase", "gene_name": "CBR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RQ3-1", "protein_name": "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "gene_name": "MCCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05165-1", "protein_name": "Propionyl-CoA carboxylase 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X9-1", "protein_name": "ATPase MORC2", "gene_name": "MORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMR5-1", "protein_name": "Lysosomal thioesterase PPT2", "gene_name": "PPT2-EGFL8; PPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11498-1", "protein_name": "Pyruvate carboxylase, mitochondrial", "gene_name": "PC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14975-1", "protein_name": "Long-chain fatty acid transport protein 2", "gene_name": "SLC27A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P86397-1", "protein_name": "Hydroxyacyl-thioester dehydratase type 2, mitochondrial", "gene_name": "HTD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50747-1", "protein_name": "Biotin--protein 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"referenced_proteins", "table_stats": [ { "field": "total", "count": 59 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues.", "journal": "International journal of cancer", "date": "1994", "authors": "Li J, Ding SF, Habib NA, Fermor BF, Wood CB, Gilmour RS", "reference": { "type": "PubMed", "id": "7909540", "url": "https://pubmed.ncbi.nlm.nih.gov/7909540" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, 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"gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N4T8-1", "protein_name": "3-oxoacyl-[acyl-carrier-protein] reductase", "gene_name": "CBR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X9-1", "protein_name": "ATPase MORC2", "gene_name": "MORC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate 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[] } ] }, { "title": "A human promyelocyte mRNA transiently induced by TPA is homologous to yeast IPP isomerase.", "journal": "Genomics", "date": "1994", "authors": "Xuan JW, Kowalski J, Chambers AF, Denhardt DT", "reference": { "type": "PubMed", "id": "8020941", "url": "https://pubmed.ncbi.nlm.nih.gov/8020941" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8020941", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Male pseudohermaphroditism caused by mutations of testicular 17 beta-hydroxysteroid dehydrogenase 3.", "journal": "Nature genetics", "date": "1994", "authors": "Geissler WM, Davis DL, Wu L, Bradshaw KD, Patel S, Mendonca BB, Elliston KO, Wilson JD, Russell DW, Andersson S", "reference": { "type": "PubMed", "id": "8075637", "url": "https://pubmed.ncbi.nlm.nih.gov/8075637" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXB9-1", "protein_name": "Very long chain fatty acid elongase 2", "gene_name": "ELOVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53GQ0-1", "protein_name": "Very-long-chain 3-oxoacyl-CoA reductase", "gene_name": "HSD17B12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYP7-1", "protein_name": "Very long chain fatty acid elongase 5", "gene_name": "ELOVL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18405-1", "protein_name": "3-oxo-5-alpha-steroid 4-dehydrogenase 1", "gene_name": "SRD5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A1L3X0-1", "protein_name": "Very long chain fatty acid elongase 7", "gene_name": "ELOVL7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Y1H2-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2", "gene_name": "HACD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01189-1", "protein_name": "Pro-opiomelanocortin", "gene_name": "POMC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05093-1", "protein_name": "Steroid 17-alpha-hydroxylase/17,20 lyase", "gene_name": "CYP17A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01229-1", "protein_name": "Lutropin subunit beta", "gene_name": "LHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKU0-4", "protein_name": "Long-chain-fatty-acid--CoA ligase 6", "gene_name": "ACSL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 5", "gene_name": "ACSL5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5FVE4-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG2", "gene_name": "ACSBG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14060-1", "protein_name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1", "gene_name": "HSD3B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26439-1", "protein_name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2", "gene_name": "HSD3B2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01215-1", "protein_name": "Glycoprotein hormones alpha chain", "gene_name": "CGA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37058-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase type 3", "gene_name": "HSD17B3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW60-1", "protein_name": "Very long chain fatty acid elongase 1", "gene_name": "ELOVL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR5-1", "protein_name": "Very long chain fatty acid elongase 4", "gene_name": "ELOVL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HB03-1", "protein_name": "Very long chain fatty acid elongase 3", "gene_name": "ELOVL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ01-1", "protein_name": "Very-long-chain enoyl-CoA reductase", "gene_name": "TECR", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0YJ81-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1", "gene_name": "HACD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8P0-1", "protein_name": "Polyprenal reductase", "gene_name": "SRD5A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P035-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "gene_name": "HACD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31213-1", "protein_name": "3-oxo-5-alpha-steroid 4-dehydrogenase 2", "gene_name": "SRD5A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWC8-1", "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4", "gene_name": "HACD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5HYJ1-1", "protein_name": "Trans-2,3-enoyl-CoA reductase-like", "gene_name": "TECRL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GR2-1", "protein_name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "gene_name": "ACSBG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60488-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 4", "gene_name": "ACSL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95573-1", "protein_name": "Fatty acid CoA ligase Acsl3", "gene_name": "ACSL3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8075637", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 33 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.", "journal": "Archives of biochemistry and biophysics", "date": "1996", "authors": "Stromstedt M, Rozman D, Waterman MR", "reference": { "type": "PubMed", "id": "8619637", "url": "https://pubmed.ncbi.nlm.nih.gov/8619637" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15742-1", "protein_name": "NGFI-A-binding protein 2", "gene_name": "NAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22570-1", "protein_name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "gene_name": "FDXR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SQ4-1", "protein_name": "Adhesion G protein-coupled receptor G6", "gene_name": "ADGRG6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A9YTQ3-1", "protein_name": "Aryl hydrocarbon receptor repressor", "gene_name": "AHRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35869-1", "protein_name": "Aryl hydrocarbon receptor", "gene_name": "AHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27540-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator", "gene_name": "ARNT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBZ2-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator 2", "gene_name": "ARNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15738-1", "protein_name": "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "gene_name": "NSDHL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56693-1", "protein_name": "Transcription factor SOX-10", "gene_name": "SOX10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56937-1", "protein_name": "3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7", "gene_name": "HSD17B7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXG9-1", "protein_name": "Adhesion G protein-coupled receptor V1", "gene_name": "ADGRV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor 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"uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15800-1", "protein_name": "Methylsterol monooxygenase 1", "gene_name": "MSMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SK9-1", "protein_name": "Stearoyl-CoA desaturase 5", "gene_name": "SCD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15392-1", "protein_name": "Delta(24)-sterol reductase", "gene_name": "DHCR24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15538-1", "protein_name": "Cytochrome P450 11B1, mitochondrial", "gene_name": "CYP11B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01189-1", "protein_name": "Pro-opiomelanocortin", "gene_name": "POMC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6A2-1", "protein_name": "Cholesterol 24-hydroxylase", "gene_name": "CYP46A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14118-1", "protein_name": "Dystroglycan 1", "gene_name": "DAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07942-1", "protein_name": "Laminin subunit beta-1", "gene_name": "LAMB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24043-1", "protein_name": "Laminin subunit alpha-2", "gene_name": "LAMA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11047-1", "protein_name": "Laminin subunit gamma-1", "gene_name": "LAMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36956-1", "protein_name": "Sterol regulatory element-binding protein 1", "gene_name": "SREBF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46939-1", "protein_name": "Utrophin", "gene_name": "UTRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01453-1", "protein_name": "Peripheral myelin protein 22", "gene_name": "PMP22", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20916-1", "protein_name": "Myelin-associated glycoprotein", "gene_name": "MAG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10109-1", "protein_name": "Adrenodoxin, mitochondrial", "gene_name": "FDX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08686-1", "protein_name": "Steroid 21-hydroxylase", "gene_name": "CYP21A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02686-1", "protein_name": "Myelin basic protein", "gene_name": "MBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05108-1", "protein_name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "gene_name": "CYP11A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZWL3-1", "protein_name": "Cytochrome P450 4V2", "gene_name": "CYP4V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19099-1", "protein_name": "Cytochrome P450 11B2, mitochondrial", "gene_name": "CYP11B2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13506-1", "protein_name": "NGFI-A-binding protein 1", "gene_name": "NAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RI1-3", "protein_name": "Bile acid receptor", "gene_name": "NR1H4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXM0-1", "protein_name": "Periaxin", "gene_name": "PRX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25189-1", "protein_name": "Myelin protein P0", "gene_name": "MPZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03052-1", "protein_name": "POU domain, class 3, transcription factor 1", "gene_name": "POU3F1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04035-1", "protein_name": "3-hydroxy-3-methylglutaryl-coenzyme A reductase", "gene_name": "HMGCR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28347-1", "protein_name": "Transcriptional enhancer factor TEF-1", "gene_name": "TEAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13474-1", "protein_name": "Dystrophin-related protein 2", "gene_name": "DRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20265-1", "protein_name": "POU domain, class 3, transcription factor 2", "gene_name": "POU3F2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11161-1", "protein_name": "E3 SUMO-protein ligase EGR2", "gene_name": "EGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P4F2-1", "protein_name": "Ferredoxin-2, mitochondrial", "gene_name": "FDX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46937-1", "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV5-1", "protein_name": "WW domain-containing transcription regulator protein 1", "gene_name": "WWTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8619637", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 92 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32377-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD1", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPQ8-1", "protein_name": "Dolichol kinase", "gene_name": "DOLK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YN1-1", "protein_name": "Dolichyldiphosphatase 1", "gene_name": "DOLPP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SQ9-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit DHDDS", "gene_name": "DHDDS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5I4-1", "protein_name": "Polyprenol dehydrogenase", "gene_name": "DHRSX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8P0-1", "protein_name": "Polyprenal reductase", "gene_name": "SRD5A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96E22-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "NUS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8626466", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Transcriptional regulation of squalene epoxidase by sterols and inhibitors in HeLa cells.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Nakamura Y, Sakakibara J, Izumi T, Shibata A, Ono T", "reference": { "type": "PubMed", "id": "8626488", "url": "https://pubmed.ncbi.nlm.nih.gov/8626488" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8626488", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Vallett SM, Sanchez HB, Rosenfeld JM, Osborne TF", "reference": { "type": "PubMed", "id": "8647822", "url": "https://pubmed.ncbi.nlm.nih.gov/8647822" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96G25-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 8", "gene_name": "MED8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15742-1", "protein_name": "NGFI-A-binding protein 2", "gene_name": "NAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY76-1", "protein_name": "Angiopoietin-related protein 4", "gene_name": "ANGPTL4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SQ4-1", "protein_name": "Adhesion G protein-coupled receptor G6", "gene_name": "ADGRG6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A9YTQ3-1", "protein_name": "Aryl hydrocarbon receptor repressor", "gene_name": "AHRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35869-1", "protein_name": "Aryl hydrocarbon receptor", "gene_name": "AHR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27540-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator", "gene_name": "ARNT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RU7-1", "protein_name": "Tribbles homolog 3", "gene_name": "TRIB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HBZ2-1", "protein_name": "Aryl hydrocarbon receptor nuclear translocator 2", "gene_name": "ARNT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H204-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 28", "gene_name": "MED28", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15327-1", "protein_name": "Ankyrin repeat domain-containing protein 1", "gene_name": "ANKRD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14192-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56693-1", "protein_name": "Transcription factor SOX-10", "gene_name": "SOX10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50416-1", "protein_name": "Carnitine O-palmitoyltransferase 1, liver isoform", "gene_name": "CPT1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71SY5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "MED25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXG9-1", "protein_name": "Adhesion G protein-coupled receptor V1", "gene_name": "ADGRV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16881-1", "protein_name": "Thioredoxin reductase 1, cytoplasmic", "gene_name": "TXNRD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23786-1", "protein_name": "Carnitine O-palmitoyltransferase 2, mitochondrial", "gene_name": "CPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22680-1", "protein_name": "Cytochrome P450 7A1", "gene_name": "CYP7A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54868-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, mitochondrial", "gene_name": "HMGCS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUE0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 18", "gene_name": "MED18", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWA0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 9", "gene_name": "MED9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86SK9-1", "protein_name": "Stearoyl-CoA desaturase 5", "gene_name": "SCD5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PCB7-1", "protein_name": "Long-chain fatty acid transport protein 1", "gene_name": "SLC27A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Q9-1", "protein_name": "Nuclear receptor coactivator 3", "gene_name": "NCOA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13227-1", "protein_name": "G protein pathway suppressor 2", "gene_name": "GPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28702-1", "protein_name": "Retinoic acid receptor RXR-beta", "gene_name": "RXRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16671-1", "protein_name": "Platelet glycoprotein 4", "gene_name": "CD36", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02928-1", "protein_name": "Cytochrome P450 4A11", "gene_name": "CYP4A11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14118-1", "protein_name": "Dystroglycan 1", "gene_name": "DAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07942-1", "protein_name": "Laminin subunit beta-1", "gene_name": "LAMB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24043-1", "protein_name": "Laminin subunit alpha-2", "gene_name": "LAMA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11047-1", "protein_name": "Laminin subunit gamma-1", "gene_name": "LAMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75448-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 24", "gene_name": "MED24", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2X0-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 16", "gene_name": "MED16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NVC6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 17", "gene_name": "MED17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX70-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 29", "gene_name": "MED29", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71F56-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 13-like", "gene_name": "MED13L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P086-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 11", "gene_name": "MED11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHV7-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 13", "gene_name": "MED13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H944-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 20", "gene_name": "MED20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P2C8-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 27", "gene_name": "MED27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULK4-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 23", "gene_name": "MED23", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60244-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 14", "gene_name": "MED14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21439-1", "protein_name": "Phosphatidylcholine translocator ABCB4", "gene_name": "ABCB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0JLT2-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 19", "gene_name": "MED19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15528-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "MED22", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTT4-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 10", "gene_name": "MED10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2W1-1", "protein_name": "Thyroid hormone receptor-associated protein 3", "gene_name": "THRAP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06520-1", "protein_name": "Sulfotransferase 2A1", "gene_name": "SULT2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46939-1", "protein_name": "Utrophin", "gene_name": "UTRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01453-1", "protein_name": "Peripheral myelin protein 22", "gene_name": "PMP22", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75586-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 6", "gene_name": "MED6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27469-1", "protein_name": "G0/G1 switch protein 2", "gene_name": "G0S2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZI5-1", "protein_name": "Grainyhead-like protein 1 homolog", "gene_name": "GRHL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48163-1", "protein_name": "NADP-dependent malic enzyme", "gene_name": "ME1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20916-1", "protein_name": "Myelin-associated glycoprotein", "gene_name": "MAG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43513-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 7", "gene_name": "MED7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07148-1", "protein_name": "Fatty acid-binding protein, liver", "gene_name": "FABP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13133-1", "protein_name": "Oxysterols receptor LXR-alpha", "gene_name": "NR1H3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01019-1", "protein_name": "Angiotensinogen", "gene_name": "AGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15379-1", "protein_name": "Histone deacetylase 3", "gene_name": "HDAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33121-1", "protein_name": "Long-chain-fatty-acid--CoA ligase 1", "gene_name": "ACSL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02652-1", "protein_name": "Apolipoprotein A-II", "gene_name": "APOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPJ6-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 4", "gene_name": "MED4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20393-1", "protein_name": "Nuclear receptor subfamily 1 group D member 1", "gene_name": "NR1D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6Q788-1", "protein_name": "Apolipoprotein A-V", "gene_name": "APOA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02686-1", "protein_name": "Myelin basic protein", "gene_name": "MBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3C7-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 31", "gene_name": "MED31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60656-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "UGT1A9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13196-1", "protein_name": "5-aminolevulinate synthase, non-specific, mitochondrial", "gene_name": "ALAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99743-1", "protein_name": "Neuronal PAS domain-containing protein 2", "gene_name": "NPAS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00327-2", "protein_name": "Basic helix-loop-helix ARNT-like protein 1", "gene_name": "BMAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15516-1", "protein_name": "Circadian locomoter output cycles protein kaput", "gene_name": "CLOCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04798-1", "protein_name": "Cytochrome P450 1A1", "gene_name": "CYP1A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13506-1", "protein_name": "NGFI-A-binding protein 1", "gene_name": "NAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RI1-3", "protein_name": "Bile acid receptor", "gene_name": "NR1H4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXM0-1", "protein_name": "Periaxin", "gene_name": "PRX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25189-1", "protein_name": "Myelin protein P0", "gene_name": "MPZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99541-1", "protein_name": "Perilipin-2", "gene_name": "PLIN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75192-1", "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03052-1", "protein_name": "POU domain, class 3, transcription factor 1", "gene_name": "POU3F1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86YN6-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-beta", "gene_name": "PPARGC1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RN5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 15", "gene_name": "MED15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EK7-1", "protein_name": "Constitutive coactivator of peroxisome proliferator-activated receptor gamma", "gene_name": "FAM120B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04035-1", "protein_name": "3-hydroxy-3-methylglutaryl-coenzyme A reductase", "gene_name": "HMGCR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZL6-1", "protein_name": "Ral guanine nucleotide dissociation stimulator-like 1", "gene_name": "RGL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28347-1", "protein_name": "Transcriptional enhancer factor TEF-1", "gene_name": "TEAD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVF5-1", "protein_name": "Rho guanine nucleotide exchange factor TIAM2", "gene_name": "TIAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75509-1", "protein_name": "Tumor necrosis factor receptor superfamily member 21", "gene_name": "TNFRSF21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24863-1", "protein_name": "Cyclin-C", "gene_name": "CCNC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49336-1", "protein_name": "Cyclin-dependent kinase 8", "gene_name": "CDK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16656-1", "protein_name": "Nuclear respiratory factor 1", "gene_name": "NRF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13503-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 21", "gene_name": "MED21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BWU1-1", "protein_name": "Cyclin-dependent kinase 19", "gene_name": "CDK19", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13474-1", "protein_name": "Dystrophin-related protein 2", "gene_name": "DRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95402-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 26", "gene_name": "MED26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HR3-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 30", "gene_name": "MED30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11474-1", "protein_name": "Steroid hormone receptor ERR1", "gene_name": "ESRRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60427-1", "protein_name": "Acyl-CoA (8-3)-desaturase", "gene_name": "FADS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20265-1", "protein_name": "POU domain, class 3, transcription factor 2", "gene_name": "POU3F2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48060-1", "protein_name": "Glioma pathogenesis-related protein 1", "gene_name": "GLIPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11161-1", "protein_name": "E3 SUMO-protein ligase EGR2", "gene_name": "EGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95477-1", "protein_name": "Phospholipid-transporting ATPase ABCA1", "gene_name": "ABCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02647-1", "protein_name": "Apolipoprotein A-I", "gene_name": "APOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46937-1", "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93074-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 12", "gene_name": "MED12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV5-1", "protein_name": "WW domain-containing transcription regulator protein 1", "gene_name": "WWTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11310-1", "protein_name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "ACADM", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8647822", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 158 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular cloning of human phosphomevalonate kinase and identification of a consensus peroxisomal targeting sequence.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Chambliss KL, Slaughter CA, Schreiner R, Hoffmann GF, Gibson KM", "reference": { "type": "PubMed", "id": "8663599", "url": "https://pubmed.ncbi.nlm.nih.gov/8663599" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q29081-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Pig" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8663599", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Synergistic binding of sterol regulatory element-binding protein and NF-Y to the farnesyl diphosphate synthase promoter is critical for sterol-regulated expression of the gene.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Ericsson J, Jackson SM, Edwards PA", "reference": { "type": "PubMed", "id": "8798690", "url": "https://pubmed.ncbi.nlm.nih.gov/8798690" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8798690", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular cloning and mapping of a human cDNA (SC5DL) encoding a protein homologous to fungal sterol-C5-desaturase.", "journal": "Cytogenetics and cell genetics", "date": "1996", "authors": "Matsushima M, Inazawa J, Takahashi E, Suzumori K, Nakamura Y", "reference": { "type": "PubMed", "id": "8976377", "url": "https://pubmed.ncbi.nlm.nih.gov/8976377" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8976377", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Abu-Elheiga L, Almarza-Ortega DB, Baldini A, Wakil SJ", "reference": { "type": "PubMed", "id": "9099716", "url": "https://pubmed.ncbi.nlm.nih.gov/9099716" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H5J4-1", "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "ELOVL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75845-1", "protein_name": "Lathosterol oxidase", "gene_name": "SC5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23511-1", "protein_name": "Nuclear transcription factor Y subunit alpha", "gene_name": "NFYA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50416-1", "protein_name": "Carnitine O-palmitoyltransferase 1, liver isoform", "gene_name": "CPT1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03181-1", "protein_name": "Peroxisome proliferator-activated receptor delta", "gene_name": "PPARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23786-1", "protein_name": "Carnitine O-palmitoyltransferase 2, mitochondrial", "gene_name": "CPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76082-1", "protein_name": "Organic cation/carnitine transporter 2", "gene_name": "SLC22A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48449-1", "protein_name": "Lanosterol synthase", "gene_name": "LSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86X55-3", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPA3-1", "protein_name": "Mid1-interacting protein 1", "gene_name": "MID1IP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03426-1", "protein_name": "Mevalonate kinase", "gene_name": "MVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37268-1", "protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43772-1", "protein_name": "Mitochondrial carnitine/acylcarnitine carrier protein", "gene_name": "SLC25A20", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92523-1", "protein_name": "Carnitine O-palmitoyltransferase 1, muscle isoform", "gene_name": "CPT1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92748-1", "protein_name": "Thyroid hormone-inducible hepatic protein", "gene_name": "THRSP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43741-1", "protein_name": "5'-AMP-activated protein kinase subunit beta-2", "gene_name": "PRKAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54646-1", "protein_name": "5'-AMP-activated protein kinase catalytic subunit alpha-2", "gene_name": "PRKAA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UGJ0-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma-2", "gene_name": "PRKAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9099716", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 51 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Multiple DNA elements for sterol regulatory element-binding protein and NF-Y are responsible for sterol-regulated transcription of the genes for human 3-hydroxy-3-methylglutaryl coenzyme A synthase and squalene synthase.", "journal": "Journal of biochemistry", "date": "1998", "authors": "Inoue J, Sato R, Maeda M", "reference": { "type": "PubMed", "id": "9604010", "url": 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"gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9604010", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3L8U1-1", "protein_name": "ATP-dependent chromatin remodeler CHD9", "gene_name": "CHD9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBM7-1", "protein_name": "7-dehydrocholesterol reductase", "gene_name": "DHCR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14324-1", "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15648-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 1", "gene_name": "MED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01581-1", "protein_name": "Hydroxymethylglutaryl-CoA synthase, cytoplasmic", "gene_name": "HMGCS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13907-1", "protein_name": "Isopentenyl-diphosphate Delta-isomerase 1", "gene_name": "IDI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60907-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1X", "gene_name": "TBL1X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6STE5-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3", "gene_name": "SMARCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95749-1", "protein_name": "Geranylgeranyl pyrophosphate synthase", "gene_name": "GGPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZK7-1", "protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25208-1", "protein_name": "Nuclear transcription factor Y subunit beta", "gene_name": "NFYB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12772-1", "protein_name": "Sterol regulatory element-binding protein 2", "gene_name": "SREBF2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RS0-1", "protein_name": "Trimethylguanosine synthase", "gene_name": "TGS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14534-1", "protein_name": "Squalene monooxygenase", "gene_name": "SQLE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYK8-1", "protein_name": "3'-5' exoribonuclease HELZ2", "gene_name": "HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9634533", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"protein_name": "Squalene synthase", "gene_name": "FDFT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20916-1", "protein_name": "Myelin-associated glycoprotein", "gene_name": "MAG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00767-1", "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02686-1", "protein_name": "Myelin basic protein", "gene_name": "MBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49327-1", "protein_name": "Fatty acid synthase", "gene_name": "FASN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13506-1", "protein_name": "NGFI-A-binding protein 1", "gene_name": "NAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCL2-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "GPAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXM0-1", "protein_name": "Periaxin", "gene_name": "PRX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25189-1", "protein_name": "Myelin protein P0", "gene_name": "MPZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03052-1", "protein_name": "POU domain, class 3, transcription factor 1", "gene_name": "POU3F1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15126-1", "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04035-1", "protein_name": 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"HELZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13952-1", "protein_name": "Nuclear transcription factor Y subunit gamma", "gene_name": "NFYC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76062-1", "protein_name": "Delta(14)-sterol reductase TM7SF2", "gene_name": "TM7SF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11161-1", "protein_name": "E3 SUMO-protein ligase EGR2", "gene_name": "EGR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00763-1", "protein_name": "Acetyl-CoA carboxylase 2", "gene_name": "ACACB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13085-1", "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46937-1", "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV5-1", "protein_name": "WW domain-containing transcription regulator protein 1", "gene_name": "WWTR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08047-1", "protein_name": "Transcription factor Sp1", "gene_name": "SP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H5J4", "url": "https://www.uniprot.org/uniprotkb/Q9H5J4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9748295", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 66 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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