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    {
        "title": "Functional asymmetry of nucleotide-binding domains in ABCG5 and ABCG8.",
        "journal": "The Journal of biological chemistry",
        "date": "2006",
        "authors": "Zhang DW, Graf GA, Gerard RD, Cohen JC, Hobbs HH",
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            "type": "PubMed",
            "id": "16352607",
            "url": "https://pubmed.ncbi.nlm.nih.gov/16352607"
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                "tax_name": "Mouse"
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        ],
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                "start_pos": 112,
                "end_pos": 112,
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                "sequence_mut": "K",
                "comment": "No effect on ATP-binding and on expression of both ABCG5 and ABCG8. No effect on sterol transport.",
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            },
            {
                "start_pos": 112,
                "end_pos": 112,
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                "sequence_mut": "M",
                "comment": "No effect on ATP-binding and on expression of both ABCG5 and ABCG8. No effect on sterol transport.",
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                ],
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            },
            {
                "start_pos": 214,
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                "sequence_org": "V",
                "sequence_mut": "I",
                "comment": "No effect on sterol transport; when associated with S-216.",
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                        "url": "https://www.uniprot.org/uniprotkb/Q9DBM0"
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            },
            {
                "start_pos": 216,
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                "comment": "No effect on sterol transport; when associated with I-214.",
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                "sequence_mut": "D",
                "comment": "Abolishes cholesterol transport activity, and nearly abolishes plant sterol transport.",
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                "start_pos": 194,
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                "sequence_mut": "V",
                "comment": "No effect on cholesterol and sitosterol transport activity; when associated with G-196.",
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                "sequence_mut": "G",
                "comment": "No effect on cholesterol and sitosterol transport activity; when associated with V-194.",
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                "comment": "No effect on cholesterol and sitosterol transport activity. Mildly reduced expression of ABCG5 and ABCG8.",
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