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Med.", "date": "2000", "authors": "Sosinowski T, Pandey A, Dixit VM, Weiss A", "reference": { "type": "PubMed", "id": "10662792", "url": "https://pubmed.ncbi.nlm.nih.gov/10662792" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q60787-1", "protein_name": "Lymphocyte cytosolic protein 2", "gene_name": "Lcp2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q60898-1", "protein_name": "Src-like-adapter", "gene_name": "Sla", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P24161-1", "protein_name": "T-cell surface glycoprotein CD3 zeta chain", "gene_name": "Cd247", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P43404-1", "protein_name": "Tyrosine-protein kinase ZAP-70", "gene_name": "Zap70", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P27870-1", "protein_name": "Proto-oncogene vav", "gene_name": "Vav1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60787", "url": "https://www.uniprot.org/uniprotkb/Q60787" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 111, "end_pos": 111, "sequence_org": "R", "sequence_mut": "E", "comment": "Abolishes localization to endosomes. 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[] } ] }, { "title": "LEM2 is a novel MAN1-related inner nuclear membrane protein associated with A-type lamins.", "journal": "Journal of cell science", "date": "2005", "authors": "Brachner A, Reipert S, Foisner R, Gotzmann J", "reference": { "type": "PubMed", "id": "16339967", "url": "https://pubmed.ncbi.nlm.nih.gov/16339967" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6DVA0-1", "protein_name": "LEM domain-containing protein 2", "gene_name": "Lemd2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P20700-1", "protein_name": "Lamin-B1", "gene_name": "LMNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99986-1", "protein_name": "Serine/threonine-protein kinase VRK1", "gene_name": "VRK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NC56-1", "protein_name": "LEM domain-containing protein 2", "gene_name": "LEMD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02545-1", "protein_name": "Prelamin-A/C", "gene_name": "LMNA", 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanistic Insights of the LEMD2 p.L13R Mutation and Its Role in Cardiomyopathy.", "journal": "Circulation research", "date": "2023-01-20", "authors": "Chen Ruping, Buchmann Simone, Kroth Amos, Arias-Loza Anahi-Paula, Kohlhaas Michael, Wagner Nicole, Gr\u00fcner Gianna, Nickel Alexander, Cirnu Alexandra, Williams Tatjana, Maack Christoph, Erg\u00fcn S\u00fcleyman, Frantz Stefan, Gerull Brenda", "reference": { "type": "PubMed", "id": "36656972", "url": "https://pubmed.ncbi.nlm.nih.gov/36656972" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6DVA0-1", "protein_name": "LEM domain-containing protein 2", "gene_name": "Lemd2", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6DVA0", "url": "https://www.uniprot.org/uniprotkb/Q6DVA0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": 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Arcos-Villacis Nathaly, Battey Edmund, Boogerd Cornelis, Orellana Constanza Avalos, Marhuenda Emilie, Swiatlowska Pamela, Hodzic Didier, Prin Fabrice, Mohun Tim, Catibog Norman, Tapia Olga, Gerace Larry, Iskratsch Thomas, Shah Ajay M, Stroud Matthew J", "reference": { "type": "PubMed", "id": "37067297", "url": "https://pubmed.ncbi.nlm.nih.gov/37067297" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6DVA0-1", "protein_name": "LEM domain-containing protein 2", "gene_name": "Lemd2", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6DVA0", "url": "https://www.uniprot.org/uniprotkb/Q6DVA0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.37067297", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"SLC7A8, a gene mapping within the lysinuric protein intolerance critical region, encodes a new member of the glycoprotein-associated amino acid transporter family.", "journal": "Genomics", "date": "1999", "authors": "Bassi M T, Sperandeo M P, Incerti B, Bulfone A, Pepe A, Surace E M, Gattuso C, De Grandi A, Buoninconti A, Riboni M, Manzoni M, Andria G, Ballabio A, Borsani G, Sebastio G", "reference": { "type": "PubMed", "id": "10610726", "url": "https://pubmed.ncbi.nlm.nih.gov/10610726" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9QXW9-1", "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "Slc7a8", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXW9", "url": "https://www.uniprot.org/uniprotkb/Q9QXW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Y+ and y+ L arginine transporters in neuronal cells expressing tyrosine hydroxylase.", "journal": "Biochimica et biophysica acta", "date": "2005", "authors": "Bae SY, Xu Q, Hutchinson D, Colton CA", "reference": { "type": "PubMed", 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8.", "journal": "Biochem. J.", "date": "2011", "authors": "Braun Doreen, Wirth Eva K, Wohlgemuth Franziska, Reix Nathalie, Klein Marc O, Gr\u00fcters Annette, K\u00f6hrle Josef, Schweizer Ulrich", "reference": { "type": "PubMed", "id": "21726201", "url": "https://pubmed.ncbi.nlm.nih.gov/21726201" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9QXW9-1", "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "Slc7a8", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXW9", "url": "https://www.uniprot.org/uniprotkb/Q9QXW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.21726201", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss.", "journal": "eLife", "date": "2018", "authors": "Espino Guarch M, Font-Llitjos M, Murillo-Cuesta S, Errasti-Murugarren E, Celaya AM, Girotto G, Vuckovic D, Mezzavilla M, Vilches C, Bodoy S, Sahun I, Gonzalez L, Prat E, Zorzano A, Dierssen M, Varela-Nieto I, Gasparini P, Palacin M, Nunes V", "reference": { "type": "PubMed", "id": "29355479", "url": "https://pubmed.ncbi.nlm.nih.gov/29355479" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9QXW9-1", "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "Slc7a8", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHI5-1", "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "SLC7A8", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXW9", "url": "https://www.uniprot.org/uniprotkb/Q9QXW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.29355479", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.", "journal": "Front. Physiol.", "date": "2019", "authors": "Kn\u00f6pfel Emilia Boiadjieva, Vilches Clara, Camargo Simone M R, Errasti-Murugarren Ekaitz, St\u00e4ubli Andrina, Mayayo Clara, Munier Francis L, Miroshnikova Nataliya, Poncet Nad\u00e8ge, Junza Alexandra, Bhattacharya Shomi S, Prat Esther, Berry Vanita, Berger Wolfgang, Heon Elise, Moore Anthony T, Yanes \u00d3scar, Nunes Virginia, Palac\u00edn Manuel, Verrey Francois, Kloeckener-Gruissem Barbara", "reference": { "type": "PubMed", "id": "31231240", "url": "https://pubmed.ncbi.nlm.nih.gov/31231240" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9QXW9-1", "protein_name": "Large neutral amino acids transporter small subunit 2", "gene_name": "Slc7a8", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9QXW9", "url": "https://www.uniprot.org/uniprotkb/Q9QXW9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.31231240", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Housekeeping genes for phylogenetic analysis of eutherian relationships.", "journal": "Mol. Biol. Evol.", "date": "2006", "authors": "Kullberg M, Nilsson MA, Arnason U, Harley EH, Janke A", "reference": { "type": "PubMed", "id": "16751257", "url": "https://pubmed.ncbi.nlm.nih.gov/16751257" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08249-1", "protein_name": "Malate dehydrogenase, mitochondrial", "gene_name": "Mdh2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P21912-1", "protein_name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "gene_name": "SDHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0QF01-1", "protein_name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "gene_name": "SDHA", "tax_name": "Pig" }, { "uniprot_canonical_ac": "Q007T0-1", "protein_name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "gene_name": "SDHB", "tax_name": "Pig" }, { "uniprot_canonical_ac": "P16858-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", 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Mol. 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mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress.", "journal": "Molecular and cellular biology", "date": "2002", "authors": "Seternes OM, Johansen B, Hegge B, Johannessen M, Keyse SM, Moens U", "reference": { "type": "PubMed", "id": "12242275", "url": "https://pubmed.ncbi.nlm.nih.gov/12242275" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O54992-1", "protein_name": "MAP kinase-activated protein kinase 5", "gene_name": "Mapkapk5", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O54992", "url": "https://www.uniprot.org/uniprotkb/O54992" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.12242275", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], 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Cell. 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"authors": "Zhao Ziheng, Wang Yan, Gao Yuhan, Ju Yurong, Zhao Ye, Wu Zhaofei, Gao Shuaixin, Zhang Boyang, Pang Xuewen, Zhang Yu, Wang Wei", "reference": { "type": "PubMed", "id": "37126714", "url": "https://pubmed.ncbi.nlm.nih.gov/37126714" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O54992-1", "protein_name": "MAP kinase-activated protein kinase 5", "gene_name": "Mapkapk5", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "O54992", "url": "https://www.uniprot.org/uniprotkb/O54992" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.37126714", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", 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Dyn.", "date": "1995", "authors": "Zhadanov AB, Bertuzzi S, Taira M, Dawid IB, Westphal H", "reference": { "type": "PubMed", "id": "7626792", "url": "https://pubmed.ncbi.nlm.nih.gov/7626792" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P50481-1", "protein_name": "LIM/homeobox protein Lhx3", "gene_name": "Lhx3", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P50481", "url": "https://www.uniprot.org/uniprotkb/P50481" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.7626792", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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Reduces weakly histone 3' end processing.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUV6", "url": "https://www.uniprot.org/uniprotkb/Q8BUV6" }, { "database": "PubMed", "id": "15824063", "url": "https://pubmed.ncbi.nlm.nih.gov/15824063" } ], "uniprot_canonical_ac": "Q8BUV6-1" }, { "start_pos": 149, "end_pos": 151, "sequence_org": "MPL", "sequence_mut": "AAA", "comment": "Does not inhibit interaction with ZNF473. Reduces weakly histone 3' end processing.", "evidence": [ { "database": "UniProtKB", "id": "Q8BUV6", "url": "https://www.uniprot.org/uniprotkb/Q8BUV6" }, { "database": "PubMed", "id": "15824063", "url": "https://pubmed.ncbi.nlm.nih.gov/15824063" } ], "uniprot_canonical_ac": "Q8BUV6-1" }, { "start_pos": 33, "end_pos": 35, "sequence_org": "PLL", "sequence_mut": "AAA", "comment": "Does not inhibit interaction with ZNF473. 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase.", "journal": "Molecular and cellular biology", "date": "2006", "authors": "Wagner EJ, Marzluff WF", "reference": { "type": "PubMed", "id": "16914750", "url": "https://pubmed.ncbi.nlm.nih.gov/16914750" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8BUV6-1", "protein_name": "U7 snRNA-associated Sm-like protein LSm11", "gene_name": "Lsm11", "tax_name": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Essential role of IPS-1 in innate immune responses against RNA viruses.", "journal": "The Journal of experimental medicine", "date": "2006", "authors": "Kumar H, Kawai T, Kato H, Sato S, Takahashi K, Coban C, Yamamoto M, Uematsu S, Ishii KJ, Takeuchi O, Akira S", "reference": { "type": "PubMed", "id": "16785313", "url": "https://pubmed.ncbi.nlm.nih.gov/16785313" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8VCF0-1", "protein_name": "Mitochondrial antiviral-signaling 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway.", "journal": "J. Biol. Chem.", "date": "2008", "authors": "Sanada T, Takaesu G, Mashima R, Yoshida R, Kobayashi T, Yoshimura A", "reference": { "type": "PubMed", "id": "18849341", "url": "https://pubmed.ncbi.nlm.nih.gov/18849341" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8VCF0-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "Mavs", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q60803-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "Traf3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q80UF7-1", "protein_name": "TIR domain-containing adapter molecule 1", "gene_name": "Ticam1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P39429-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "Traf2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P39428-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "Traf1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P70196-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "Traf6", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q3UDK1-1", "protein_name": "TRAF-type zinc finger domain-containing protein 1", "gene_name": "Trafd1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8VCF0", "url": "https://www.uniprot.org/uniprotkb/Q8VCF0" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.18849341", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ndfip1 negatively regulates RIG-I-dependent immune signaling by enhancing E3 ligase Smurf1-mediated MAVS degradation.", "journal": "J. Immunol.", "date": "2012", "authors": "Wang Y, Tong X, Ye X", "reference": { "type": "PubMed", "id": "23087404", "url": "https://pubmed.ncbi.nlm.nih.gov/23087404" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8VCF0-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "Mavs", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CUN6-1", "protein_name": "E3 ubiquitin-protein ligase SMURF1", "gene_name": "Smurf1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCE7-1", "protein_name": "E3 ubiquitin-protein ligase SMURF1", "gene_name": "SMURF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT67-1", "protein_name": "NEDD4 family-interacting protein 1", "gene_name": "NDFIP1", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { 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Biol.", "date": "2001", "authors": "Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN", "reference": { "type": "PubMed", "id": "11397016", "url": "https://pubmed.ncbi.nlm.nih.gov/11397016" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99MV5-1", "protein_name": "RNA helicase Mov10l1", "gene_name": "Mov10l1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99MV5", "url": "https://www.uniprot.org/uniprotkb/Q99MV5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.11397016", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", 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Biol. Chem.", "date": "2003", "authors": "Ueyama T, Kasahara H, Ishiwata T, Yamasaki N, Izumo S", "reference": { "type": "PubMed", "id": "12754203", "url": "https://pubmed.ncbi.nlm.nih.gov/12754203" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99MV5-1", "protein_name": "RNA helicase Mov10l1", "gene_name": "Mov10l1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99MV5", "url": "https://www.uniprot.org/uniprotkb/Q99MV5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.12754203", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.", "journal": "Genes & development", "date": "2015", "authors": "Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ", "reference": { "type": "PubMed", "id": "25762440", "url": "https://pubmed.ncbi.nlm.nih.gov/25762440" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99MV5-1", "protein_name": "RNA helicase Mov10l1", "gene_name": "Mov10l1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SWZ9-1", "protein_name": "Mitochondrial cardiolipin hydrolase", "gene_name": "Pld6", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99MV5", "url": "https://www.uniprot.org/uniprotkb/Q99MV5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 778, "end_pos": 778, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of RNA helicase activity. 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LINE1 retrotransposons are derepressed and piRNA biogenesis is abolished.", "evidence": [ { "database": "UniProtKB", "id": "Q99MV5", "url": "https://www.uniprot.org/uniprotkb/Q99MV5" }, { "database": "PubMed", "id": "25762440", "url": "https://pubmed.ncbi.nlm.nih.gov/25762440" } ], "uniprot_canonical_ac": "Q99MV5-1" } ], "record_id": "pubmed.25762440", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "yama, a mutant allele of Mov10l1, disrupts retrotransposon silencing and piRNA biogenesis.", "journal": "PLoS genetics", "date": "2021", "authors": "Guan Y, Keeney S, Jain D, Wang PJ", "reference": { "type": "PubMed", "id": "33635934", "url": "https://pubmed.ncbi.nlm.nih.gov/33635934" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99MV5-1", "protein_name": "RNA helicase Mov10l1", "gene_name": "Mov10l1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99MV5", "url": "https://www.uniprot.org/uniprotkb/Q99MV5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.33635934", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction.", "journal": "The Journal of biological chemistry", "date": "2017", "authors": "Shiraishi A, Uruno T, Sanematsu F, Ushijima M, Sakata D, Hara T, Fukui Y", "reference": { "type": "PubMed", "id": "28028174", "url": "https://pubmed.ncbi.nlm.nih.gov/28028174" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9D6I9-1", "protein_name": "Leucine rich adaptor protein 1", "gene_name": "Lurap1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D6I9", "url": "https://www.uniprot.org/uniprotkb/Q9D6I9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.28028174", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human and mouse SLC25A29 mitochondrial transporters rescue the deficient ornithine metabolism in fibroblasts of patients with the hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome.", "journal": "Pediatr. Res.", "date": "2009", "authors": "Camacho JA, Rioseco-Camacho N", "reference": { "type": "PubMed", "id": "19287344", "url": "https://pubmed.ncbi.nlm.nih.gov/19287344" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Z2Z6-1", "protein_name": "Mitochondrial carnitine/acylcarnitine carrier protein", "gene_name": "Slc25a20", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BL03-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "Slc25a29", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CFJ7-1", "protein_name": "Methylated amino-acid transporter SLC25A45", "gene_name": "Slc25a45", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WVD5-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "Slc25a15", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8R3-1", "protein_name": "Mitochondrial basic amino acids transporter", "gene_name": "SLC25A29", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z2Z6", "url": "https://www.uniprot.org/uniprotkb/Q9Z2Z6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.19287344", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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[] } ] }, { "title": "Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells.", "journal": "Biochimica et biophysica acta", "date": "2009", "authors": "Gutgesell A, Wen G, Konig B, Koch A, Spielmann J, Stangl GI, Eder K, Ringseis R", "reference": { "type": "PubMed", "id": "19577614", "url": "https://pubmed.ncbi.nlm.nih.gov/19577614" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Z2Z6-1", "protein_name": "Mitochondrial carnitine/acylcarnitine carrier protein", "gene_name": "Slc25a20", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z2Z6", "url": "https://www.uniprot.org/uniprotkb/Q9Z2Z6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.19577614", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": 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