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Biol. Chem.", "date": "2010", "authors": "Tando Toshio, Ishizaka Aya, Watanabe Hirotaka, Ito Taiji, Iida Shun, Haraguchi Takeshi, Mizutani Taketoshi, Izumi Tomonori, Isobe Toshiaki, Akiyama Taishin, Inoue Jun-ichiro, Iba Hideo", "reference": { "type": "PubMed", "id": "20460684", "url": "https://pubmed.ncbi.nlm.nih.gov/20460684" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51531-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "gene_name": "SMARCA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12824-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "gene_name": "SMARCB1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.", "journal": "Nature genetics", "date": "2013-06", "authors": "Kadoch Cigall, Hargreaves Diana C, Hodges Courtney, Elias Laura, Ho Lena, Ranish Jeff, Crabtree Gerald R", 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Butyryllysine and Crotonyllysine Histone Peptide Modifications.", "journal": "Structure (London, England : 1993)", "date": "2015", "authors": "Flynn EM, Huang OW, Poy F, Oppikofer M, Bellon SF, Tang Y, Cochran AG", "reference": { "type": "PubMed", "id": "26365797", "url": "https://pubmed.ncbi.nlm.nih.gov/26365797" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51531-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "gene_name": "SMARCA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51532-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4", "gene_name": "SMARCA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12824-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "gene_name": "SMARCB1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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Med. Chem.", "date": "2025", "authors": "Li Zhenwu, Harikrishnan Lalgudi S, Xu Guozhang, Samanta Debangshu, Clemente Jose C, Leng Lingying, Tu Wenbin, Yang Lin, Huang Liyue, Wang Mi, Wang Shaomeng, Deng Qiaolin, Behshad Elham, Nagilla Rakesh, Orth Peter, Rice Cory, Strickland Corey, Mohammad Helai P, Priestley E Scott, Sui Zhihua", "reference": { "type": "PubMed", "id": "39570797", "url": "https://pubmed.ncbi.nlm.nih.gov/39570797" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51531-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2", "gene_name": "SMARCA2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51531", "url": "https://www.uniprot.org/uniprotkb/P51531" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.39570797", "abstract": "", 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Biol. Chem.", "date": "1999", "authors": "Braverman LE, Quilliam LA", "reference": { "type": "PubMed", "id": "10026169", "url": "https://pubmed.ncbi.nlm.nih.gov/10026169" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16513-1", "protein_name": "Serine/threonine-protein kinase N2", "gene_name": "PKN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": 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SLP-76 in Jurkat T cells.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Boerth NJ, Judd BA, Koretzky GA", "reference": { "type": "PubMed", "id": "10671560", "url": "https://pubmed.ncbi.nlm.nih.gov/10671560" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13177-1", "protein_name": "Serine/threonine-protein kinase PAK 2", "gene_name": "PAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43561-1", "protein_name": "Linker for activation of T-cells family member 1", "gene_name": "LAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75791-1", "protein_name": "GRB2-related adapter protein 2", "gene_name": "GRAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75914-1", "protein_name": "Serine/threonine-protein kinase PAK 3", "gene_name": "PAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20036-1", "protein_name": "HLA class II histocompatibility antigen, DP alpha 1 chain", "gene_name": "HLA-DPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01737-1", "protein_name": "T cell receptor alpha variable 8-4", "gene_name": "TRAV8-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04437-1", "protein_name": "T cell receptor alpha variable 29/delta variable 5", "gene_name": "TRAV29DV5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A0A6YYK7-1", "protein_name": "T cell receptor alpha variable 19", "gene_name": "TRAV19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01920-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 1 chain", 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protein 1", "gene_name": "FYB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04435-1", "protein_name": "T cell receptor beta variable 7-9", "gene_name": "TRBV7-9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01733-1", "protein_name": "T cell receptor beta variable 12-3", "gene_name": "TRBV12-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93033-1", "protein_name": "Immunoglobulin superfamily member 2", "gene_name": "CD101", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01848-1", "protein_name": "T cell receptor alpha chain constant", "gene_name": "TRAC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01850-1", "protein_name": "T cell receptor beta constant 1", "gene_name": "TRBC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07766-1", "protein_name": "T-cell surface glycoprotein CD3 epsilon chain", "gene_name": "CD3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13094-1", "protein_name": "Lymphocyte cytosolic protein 2", "gene_name": "LCP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43403-1", "protein_name": "Tyrosine-protein kinase ZAP-70", "gene_name": "ZAP70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01909-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 1 chain", "gene_name": "HLA-DQA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04440-1", "protein_name": "HLA class II histocompatibility antigen, DP beta 1 chain", "gene_name": "HLA-DPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05538-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 2 chain", "gene_name": "HLA-DQB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13762-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 4 chain", "gene_name": "HLA-DRB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30154-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 5 chain", "gene_name": "HLA-DRB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01903-1", "protein_name": "HLA class II histocompatibility antigen, DR alpha chain", "gene_name": "HLA-DRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P79483-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 3 chain", "gene_name": "HLA-DRB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N8S7-1", "protein_name": "Protein enabled homolog", "gene_name": "ENAH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08881-1", "protein_name": "Tyrosine-protein kinase ITK/TSK", "gene_name": "ITK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50552-1", "protein_name": "Vasodilator-stimulated phosphoprotein", "gene_name": "VASP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 559, "end_pos": 559, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "IntAct", "id": "O15117", "url": "https://www.ebi.ac.uk/intact/interactors/id:O15117*" }, { "database": "iPTMnet", "id": "O15117", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O15117" }, { "database": "PubMed", "id": "10671560", "url": "https://pubmed.ncbi.nlm.nih.gov/10671560" } ], "site_lbl": "Tyr559", "uniprot_canonical_ac": "O15117-1" } ], "record_id": "pubmed.10671560", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton.", "journal": "The Journal of cell biology", "date": "2000", "authors": "Krause M, Sechi AS, Konradt M, Monner D, Gertler FB, Wehland J", "reference": { "type": "PubMed", "id": "10747096", "url": "https://pubmed.ncbi.nlm.nih.gov/10747096" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13177-1", "protein_name": "Serine/threonine-protein kinase PAK 2", "gene_name": "PAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43561-1", "protein_name": "Linker for activation of T-cells family member 1", "gene_name": "LAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75791-1", "protein_name": "GRB2-related adapter protein 2", "gene_name": "GRAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09693-1", "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75914-1", "protein_name": "Serine/threonine-protein kinase PAK 3", "gene_name": "PAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20036-1", "protein_name": "HLA class II histocompatibility antigen, DP alpha 1 chain", "gene_name": "HLA-DPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01737-1", "protein_name": "T cell receptor alpha variable 8-4", "gene_name": "TRAV8-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04437-1", "protein_name": "T cell receptor alpha variable 29/delta variable 5", "gene_name": "TRAV29DV5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A0A6YYK7-1", "protein_name": "T cell receptor alpha variable 19", "gene_name": "TRAV19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01920-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 1 chain", "gene_name": "HLA-DQB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01906-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 2 chain", "gene_name": "HLA-DQA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01911-1", "protein_name": "HLA class II histocompatibility antigen, DRB1 beta chain", "gene_name": "HLA-DRB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UI08-1", "protein_name": "Ena/VASP-like protein", "gene_name": "EVL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42768-1", "protein_name": "Actin nucleation-promoting factor WAS", "gene_name": "WAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16885-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "PLCG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15117-1", "protein_name": "FYN-binding protein 1", "gene_name": "FYB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04435-1", "protein_name": "T cell receptor beta variable 7-9", "gene_name": "TRBV7-9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01733-1", "protein_name": "T cell receptor beta variable 12-3", "gene_name": "TRBV12-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93033-1", "protein_name": "Immunoglobulin superfamily member 2", "gene_name": "CD101", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01848-1", "protein_name": "T cell receptor alpha chain constant", "gene_name": "TRAC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01850-1", "protein_name": "T cell receptor beta constant 1", "gene_name": "TRBC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07766-1", "protein_name": "T-cell surface glycoprotein CD3 epsilon chain", "gene_name": "CD3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13094-1", "protein_name": "Lymphocyte cytosolic protein 2", "gene_name": "LCP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43403-1", "protein_name": "Tyrosine-protein kinase ZAP-70", "gene_name": "ZAP70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01909-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 1 chain", "gene_name": "HLA-DQA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04440-1", "protein_name": "HLA class II histocompatibility antigen, DP beta 1 chain", "gene_name": "HLA-DPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05538-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 2 chain", "gene_name": "HLA-DQB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13762-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 4 chain", "gene_name": "HLA-DRB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30154-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 5 chain", "gene_name": "HLA-DRB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01903-1", "protein_name": "HLA class II histocompatibility antigen, DR alpha chain", "gene_name": "HLA-DRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P79483-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 3 chain", "gene_name": "HLA-DRB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N8S7-1", "protein_name": "Protein enabled homolog", "gene_name": "ENAH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08881-1", "protein_name": "Tyrosine-protein kinase ITK/TSK", "gene_name": "ITK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50552-1", "protein_name": "Vasodilator-stimulated phosphoprotein", "gene_name": "VASP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10747096", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation.", "journal": "Molecular and cellular biology", "date": "2000", "authors": "Zhao ZS, Manser E, Lim L", "reference": { "type": "PubMed", "id": "10805734", "url": "https://pubmed.ncbi.nlm.nih.gov/10805734" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13177-1", "protein_name": "Serine/threonine-protein kinase PAK 2", "gene_name": "PAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94813-1", "protein_name": "Slit homolog 2 protein", "gene_name": "SLIT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P286-1", "protein_name": "Serine/threonine-protein kinase PAK 5", "gene_name": "PAK5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75914-1", "protein_name": "Serine/threonine-protein kinase PAK 3", "gene_name": "PAK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQU5-1", "protein_name": "Serine/threonine-protein kinase PAK 6", "gene_name": "PAK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07890-1", "protein_name": "Son of sevenless homolog 2", "gene_name": "SOS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6N7-1", "protein_name": "Roundabout homolog 1", "gene_name": "ROBO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96013-1", "protein_name": "Serine/threonine-protein kinase PAK 4", "gene_name": "PAK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 21, "end_pos": 21, "kinase_uniprot_canonical_ac": "Q13153-1", "kinase_gene_name": "PAK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q13153", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q13153" }, { "database": "PubMed", "id": "10805734", "url": "https://pubmed.ncbi.nlm.nih.gov/10805734" }, { "database": "PubMed", "id": "9032240", "url": "https://pubmed.ncbi.nlm.nih.gov/9032240" }, { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" }, { "database": "PubMed", "id": "14585966", "url": "https://pubmed.ncbi.nlm.nih.gov/14585966" } ], "site_lbl": "Ser21", "uniprot_canonical_ac": "Q13153-1" } ], "record_id": "pubmed.10805734", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Zhang W, Trible RP, Zhu M, Liu SK, McGlade CJ, Samelson LE", "reference": { "type": "PubMed", "id": "10811803", "url": "https://pubmed.ncbi.nlm.nih.gov/10811803" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13177-1", "protein_name": "Serine/threonine-protein kinase PAK 2", "gene_name": "PAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26717-1", "protein_name": "NKG2-C type II integral membrane protein", "gene_name": "KLRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26718-1", "protein_name": "NKG2-D type II integral membrane protein", "gene_name": "KLRK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13747-1", "protein_name": "HLA class I histocompatibility antigen, alpha chain E", "gene_name": "HLA-E", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43561-1", "protein_name": "Linker for activation of T-cells family member 1", "gene_name": "LAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75791-1", "protein_name": "GRB2-related adapter protein 2", "gene_name": "GRAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04234-1", "protein_name": "T-cell surface 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"uniprot_canonical_ac": "Q9UI08-1", "protein_name": "Ena/VASP-like protein", "gene_name": "EVL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61769-1", "protein_name": "Beta-2-microglobulin", "gene_name": "B2M", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42768-1", "protein_name": "Actin nucleation-promoting factor WAS", "gene_name": "WAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16885-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "PLCG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKW4-1", "protein_name": "Guanine nucleotide exchange factor VAV3", "gene_name": "VAV3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15117-1", "protein_name": "FYN-binding protein 1", "gene_name": "FYB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04435-1", "protein_name": "T cell receptor beta variable 7-9", "gene_name": "TRBV7-9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01733-1", "protein_name": "T cell receptor beta variable 12-3", "gene_name": "TRBV12-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43914-1", "protein_name": "TYRO protein tyrosine kinase-binding protein", "gene_name": "TYROBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93033-1", "protein_name": "Immunoglobulin superfamily member 2", "gene_name": "CD101", "tax_name": 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"uniprot_canonical_ac": "P01909-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 1 chain", "gene_name": "HLA-DQA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04440-1", "protein_name": "HLA class II histocompatibility antigen, DP beta 1 chain", "gene_name": "HLA-DPB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05538-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 2 chain", "gene_name": "HLA-DQB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13762-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 4 chain", "gene_name": "HLA-DRB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30154-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 5 chain", "gene_name": "HLA-DRB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01903-1", "protein_name": "HLA class II histocompatibility antigen, DR alpha chain", "gene_name": "HLA-DRA", "tax_name": "Human" }, { "uniprot_canonical_ac": 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integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Hehner SP, Hofmann TG, Dienz O, Droge W, Schmitz ML", "reference": { "type": "PubMed", "id": "10849438", "url": "https://pubmed.ncbi.nlm.nih.gov/10849438" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13177-1", "protein_name": "Serine/threonine-protein kinase PAK 2", "gene_name": "PAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33681-1", "protein_name": "T-lymphocyte activation antigen CD80", "gene_name": "CD80", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10747-1", "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75914-1", 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{ "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20036-1", "protein_name": "HLA class II histocompatibility antigen, DP alpha 1 chain", "gene_name": "HLA-DPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01737-1", "protein_name": "T cell receptor alpha variable 8-4", "gene_name": "TRAV8-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04437-1", "protein_name": "T cell receptor alpha variable 29/delta variable 5", "gene_name": "TRAV29DV5", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A0A6YYK7-1", "protein_name": "T cell receptor alpha variable 19", "gene_name": "TRAV19", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01920-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 1 chain", "gene_name": "HLA-DQB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01906-1", "protein_name": "HLA class II histocompatibility antigen, DQ alpha 2 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"Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43914-1", "protein_name": "TYRO protein tyrosine kinase-binding protein", "gene_name": "TYROBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93033-1", "protein_name": "Immunoglobulin superfamily member 2", "gene_name": "CD101", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01848-1", "protein_name": "T cell receptor alpha chain constant", "gene_name": "TRAC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZC2-1", "protein_name": "Triggering receptor expressed on myeloid cells 2", "gene_name": "TREM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01850-1", "protein_name": "T cell receptor beta constant 1", "gene_name": "TRBC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07766-1", "protein_name": "T-cell surface glycoprotein CD3 epsilon 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"uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50552-1", "protein_name": "Vasodilator-stimulated phosphoprotein", "gene_name": "VASP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11390650", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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{ "uniprot_canonical_ac": "P05538-1", "protein_name": "HLA class II histocompatibility antigen, DQ beta 2 chain", "gene_name": "HLA-DQB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13762-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 4 chain", "gene_name": "HLA-DRB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q30154-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 5 chain", "gene_name": "HLA-DRB5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01903-1", "protein_name": "HLA class II histocompatibility antigen, DR alpha chain", "gene_name": "HLA-DRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P79483-1", "protein_name": "HLA class II histocompatibility antigen, DR beta 3 chain", "gene_name": "HLA-DRB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N8S7-1", "protein_name": "Protein enabled homolog", "gene_name": "ENAH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08881-1", "protein_name": 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"field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Rider L, Shatrova A, Feener EP, Webb L, Diakonova M", "reference": { "type": "PubMed", "id": "17726028", "url": "https://pubmed.ncbi.nlm.nih.gov/17726028" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 153, "end_pos": 153, "kinase_uniprot_canonical_ac": "O60674-1", "kinase_gene_name": "JAK2", "residue": "Tyr", 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}, { "title": "MORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage response.", "journal": "Cell reports", "date": "2012", "authors": "Li DQ, Nair SS, Ohshiro K, Kumar A, Nair VS, Pakala SB, Reddy SD, Gajula RP, Eswaran J, Aravind L, Kumar R", "reference": { "type": "PubMed", "id": "23260667", "url": "https://pubmed.ncbi.nlm.nih.gov/23260667" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q13153-1", "protein_name": "Serine/threonine-protein kinase PAK 1", "gene_name": "PAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X9-1", "protein_name": "ATPase MORC2", "gene_name": "MORC2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q13153", "url": "https://www.uniprot.org/uniprotkb/Q13153" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { 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