[ { "title": "An NADPH sensor protein (HSCARG) down-regulates nitric oxide synthesis by association with argininosuccinate synthetase and is essential for epithelial cell viability.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Zhao Y, Zhang J, Li H, Li Y, Ren J, Luo M, Zheng X", "reference": { "type": "PubMed", "id": "18263583", "url": "https://pubmed.ncbi.nlm.nih.gov/18263583" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, mitochondrial", "gene_name": "ARG2", "tax_name": "Human" }, { 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"Isolation and characterization of argininosuccinate synthetase from human liver.", "journal": "Biochemistry", "date": "1979", "authors": "O'Brien WE", "reference": { "type": "PubMed", "id": "518841", "url": "https://pubmed.ncbi.nlm.nih.gov/518841" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, mitochondrial", "gene_name": "ARG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05089-1", "protein_name": "Arginase-1", "gene_name": "ARG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXI2-1", "protein_name": 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[] } ] }, { "title": "Human carbamylphosphate synthetase I. Stabilization, purification, and partial characterization of the enzyme from human liver.", "journal": "The Journal of biological chemistry", "date": "1980", "authors": "Pierson DL, Brien JM", "reference": { "type": "PubMed", "id": "6249820", "url": "https://pubmed.ncbi.nlm.nih.gov/6249820" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, mitochondrial", "gene_name": "ARG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05089-1", "protein_name": "Arginase-1", "gene_name": "ARG1", "tax_name": "Human" }, { 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure and expression of a complementary DNA for the nuclear coded precursor of human mitochondrial ornithine transcarbamylase.", "journal": "Science (New York, N.Y.)", "date": "1984", "authors": "Horwich AL, Fenton WA, Williams KR, Kalousek F, Kraus JP, Doolittle RF, Konigsberg W, Rosenberg LE", "reference": { "type": "PubMed", "id": "6372096", "url": "https://pubmed.ncbi.nlm.nih.gov/6372096" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, 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transporter 1", "gene_name": "SLC25A15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HBL8", "url": "https://www.uniprot.org/uniprotkb/Q9HBL8" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 15, "end_pos": 15, "sequence_org": "R", "sequence_mut": "G", "comment": "Loss of cleavage of the transit peptide and loss of localization to mitochondrial matrix; when associated with G-23 and G-26.", "evidence": [ { "database": "UniProtKB", "id": "P00480", "url": "https://www.uniprot.org/uniprotkb/P00480" }, { "database": "PubMed", "id": "6372096", "url": "https://pubmed.ncbi.nlm.nih.gov/6372096" } ], "uniprot_canonical_ac": "P00480-1" } ], "record_id": "pubmed.6372096", "abstract": "", "glycosylation": 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"date": "1996", "authors": "Gotoh T, Sonoki T, Nagasaki A, Terada K, Takiguchi M, Mori M", "reference": { "type": "PubMed", "id": "8898077", "url": "https://pubmed.ncbi.nlm.nih.gov/8898077" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, mitochondrial", "gene_name": "ARG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05089-1", "protein_name": "Arginase-1", "gene_name": "ARG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXI2-1", "protein_name": "Mitochondrial ornithine transporter 2", "gene_name": 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Kern RM, Grody WW, Cederbaum S", "reference": { "type": "PubMed", "id": "9686347", "url": "https://pubmed.ncbi.nlm.nih.gov/9686347" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, mitochondrial", "gene_name": "ARG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05089-1", "protein_name": "Arginase-1", "gene_name": "ARG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXI2-1", "protein_name": "Mitochondrial ornithine transporter 2", "gene_name": "SLC25A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N159-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "NAGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00480-1", "protein_name": "Ornithine transcarbamylase, mitochondrial", "gene_name": "OTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXA8-1", "protein_name": "NAD-dependent protein deacylase sirtuin-5, mitochondrial", "gene_name": "SIRT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31327-1", "protein_name": "Carbamoyl-phosphate synthase [ammonia], mitochondrial", "gene_name": "CPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y619-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "SLC25A15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HBL8", "url": 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ornithine transcarbamoylase complexed with N-phosphonacetyl-L-ornithine. Catalytic mechanism and correlation with inherited deficiency.", "journal": "The Journal of biological chemistry", "date": "1998-12-18", "authors": "Shi D, Morizono H, Ha Y, Aoyagi M, Tuchman M, Allewell N M", "reference": { "type": "PubMed", "id": "9852088", "url": "https://pubmed.ncbi.nlm.nih.gov/9852088" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HBL8-1", "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00966-1", "protein_name": "Argininosuccinate synthase", "gene_name": "ASS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04424-1", "protein_name": "Argininosuccinate lyase", "gene_name": "ASL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78540-1", "protein_name": "Arginase-2, mitochondrial", "gene_name": "ARG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05089-1", "protein_name": "Arginase-1", "gene_name": "ARG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXI2-1", "protein_name": "Mitochondrial ornithine transporter 2", "gene_name": "SLC25A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N159-1", "protein_name": "N-acetylglutamate synthase, mitochondrial", "gene_name": "NAGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00480-1", "protein_name": "Ornithine transcarbamylase, mitochondrial", "gene_name": "OTC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXA8-1", "protein_name": "NAD-dependent protein deacylase sirtuin-5, mitochondrial", "gene_name": "SIRT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31327-1", "protein_name": "Carbamoyl-phosphate synthase [ammonia], mitochondrial", "gene_name": "CPS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y619-1", "protein_name": "Mitochondrial ornithine transporter 1", "gene_name": "SLC25A15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HBL8", "url": "https://www.uniprot.org/uniprotkb/Q9HBL8" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9852088", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"authors": "Hori A, Morand A, Ikebe C, Frith D, Snijders AP, Toda T", "reference": { "type": "PubMed", "id": "26545777", "url": "https://pubmed.ncbi.nlm.nih.gov/26545777" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9P2S5-1", "protein_name": "WD repeat-containing protein WRAP73", "gene_name": "WRAP73", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2D8-1", "protein_name": "Afadin- and alpha-actinin-binding protein", "gene_name": "SSX2IP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9P2S5", "url": "https://www.uniprot.org/uniprotkb/Q9P2S5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26545777", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families.", "journal": "Human molecular genetics", "date": "2021", "authors": "Madhangi M, Dutta D, Show S, Bhat VK, Rather MI, Tiwari A, Singh N, Duvvari MR, Murthy GJ, Kumar A, Nongthomba U", "reference": { "type": "PubMed", "id": "33693649", "url": "https://pubmed.ncbi.nlm.nih.gov/33693649" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mitotic Maturation Compensates for Premature Centrosome Splitting and PCM Loss in Human cep135 Knockout Cells.", "journal": "Cells", "date": "2022", "authors": "Chu Z, Gruss OJ", "reference": { "type": "PubMed", "id": "35406752", "url": "https://pubmed.ncbi.nlm.nih.gov/35406752" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9P2S5-1", "protein_name": "WD repeat-containing protein WRAP73", "gene_name": "WRAP73", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q66GS9-1", "protein_name": "Centrosomal protein of 135 kDa", "gene_name": "CEP135", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2D8-1", "protein_name": "Afadin- 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cathepsin B activity regulation. Heparin-like glycosaminogylcans protect human cathepsin B from alkaline pH-induced inactivation.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Almeida PC, Nantes IL, Chagas JR, Rizzi CC, Faljoni-Alario A, Carmona E, Juliano L, Nader HB, Tersariol IL", "reference": { "type": "PubMed", "id": "11016923", "url": "https://pubmed.ncbi.nlm.nih.gov/11016923" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11016923", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Inhibition of MEPE cleavage by Phex.", "journal": "Biochemical and biophysical research communications", "date": "2002", "authors": "Guo R, Rowe PS, Liu S, Simpson LG, Xiao ZS, Quarles LD", "reference": { "type": "PubMed", "id": "12220505", "url": "https://pubmed.ncbi.nlm.nih.gov/12220505" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8K4L6-1", "protein_name": "Matrix extracellular phosphoglycoprotein", "gene_name": "Mepe", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P78562-1", "protein_name": "Phosphate-regulating neutral endopeptidase PHEX", "gene_name": "PHEX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ76-1", "protein_name": "Matrix extracellular phosphoglycoprotein", "gene_name": "MEPE", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12220505", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TLR9 signals after translocating from the ER to CpG DNA in the lysosome.", "journal": "Nature immunology", "date": "2004", "authors": "Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT", "reference": { "type": "PubMed", "id": "14716310", "url": "https://pubmed.ncbi.nlm.nih.gov/14716310" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT09-1", "protein_name": "Protein canopy homolog 3", "gene_name": "CNPY3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", 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Comparison with normal liver cathepsin B.", "journal": "Biochem. J.", "date": "1992", "authors": "Moin K, Day NA, Sameni M, Hasnain S, Hirama T, Sloane BF", "reference": { "type": "PubMed", "id": "1637335", "url": "https://pubmed.ncbi.nlm.nih.gov/1637335" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1637335", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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Biochem.", "date": "2006", "authors": "Liu JP, Liu NS, Yuan HY, Guo Q, Lu H, Li YY", "reference": { "type": "PubMed", "id": "16733801", "url": "https://pubmed.ncbi.nlm.nih.gov/16733801" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBC3-1", "protein_name": "SH3KBP1-binding protein 1", "gene_name": "SHKBP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16733801", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], 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"uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43235-1", "protein_name": "Cathepsin K", "gene_name": "CTSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1C4-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "UNC93B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14625-1", "protein_name": "Endoplasmin", "gene_name": "HSP90B1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16857668", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Herpes simplex virus encephalitis in human UNC-93B deficiency.", "journal": "Science (New York, N.Y.)", "date": "2006", "authors": "Casrouge A, Zhang SY, Eidenschenk C, Jouanguy E, Puel A, Yang K, Alcais A, Picard C, Mahfoufi N, Nicolas N, Lorenzo L, Plancoulaine S, Senechal B, Geissmann F, Tabeta K, Hoebe K, Du X, Miller RL, Heron B, Mignot C, de Villemeur TB, Lebon P, Dulac O, Rozenberg F, Beutler B, Tardieu M, Abel L, Casanova JL", "reference": { "type": "PubMed", "id": "16973841", "url": "https://pubmed.ncbi.nlm.nih.gov/16973841" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT09-1", "protein_name": "Protein canopy homolog 3", "gene_name": "CNPY3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43235-1", "protein_name": "Cathepsin K", "gene_name": "CTSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1C4-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "UNC93B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14625-1", "protein_name": "Endoplasmin", "gene_name": "HSP90B1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16973841", "abstract": "", 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages.", "journal": "Immunity", "date": "2007", "authors": "Yang Y, Liu B, Dai J, Srivastava PK, Zammit DJ, Lefrancois L, Li Z", "reference": { "type": "PubMed", "id": "17275357", "url": "https://pubmed.ncbi.nlm.nih.gov/17275357" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT09-1", "protein_name": "Protein canopy homolog 3", "gene_name": "CNPY3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43235-1", "protein_name": "Cathepsin K", "gene_name": "CTSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1C4-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "UNC93B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14625-1", "protein_name": "Endoplasmin", "gene_name": "HSP90B1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17275357", 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.", "journal": "The Journal of cell biology", "date": "2007", "authors": "Brinkmann MM, Spooner E, Hoebe K, Beutler B, Ploegh HL, Kim YM", 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"uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9EQU3-1", "protein_name": "Toll-like receptor 9", "gene_name": "Tlr9", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BT09-1", "protein_name": "Protein canopy homolog 3", "gene_name": "CNPY3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43235-1", "protein_name": "Cathepsin K", "gene_name": "CTSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1C4-1", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response.", "journal": "Human immunology", "date": "2007", "authors": "Koehn J, Huesken D, Jaritz M, Rot A, Zurini M, Dwertmann A, Beutler B, Korthauer U", "reference": { "type": "PubMed", "id": "18082565", "url": "https://pubmed.ncbi.nlm.nih.gov/18082565" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT09-1", "protein_name": "Protein canopy homolog 3", "gene_name": "CNPY3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cathepsins are required for Toll-like receptor 9 responses.", "journal": "Biochemical and biophysical research communications", "date": "2008", "authors": "Matsumoto F, Saitoh S, Fukui R, Kobayashi T, Tanimura N, Konno K, Kusumoto Y, Akashi-Takamura S, Miyake K", "reference": { "type": "PubMed", "id": "18166152", "url": "https://pubmed.ncbi.nlm.nih.gov/18166152" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { 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"gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.", "journal": "Nature", "date": "2008", "authors": "Kim YM, Brinkmann MM, Paquet ME, Ploegh HL", "reference": { "type": "PubMed", "id": "18305481", "url": "https://pubmed.ncbi.nlm.nih.gov/18305481" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58681-1", "protein_name": "Toll-like receptor 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}, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43235-1", "protein_name": "Cathepsin K", "gene_name": "CTSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1C4-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "UNC93B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14625-1", "protein_name": "Endoplasmin", "gene_name": "HSP90B1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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Mol. Genet.", "date": "2008", "authors": "Royer-Zemmour Barbara, Ponsole-Lenfant Magali, Gara Hyam, Roll Patrice, L\u00e9v\u00eaque Christian, Massacrier Annick, Ferracci G\u00e9raldine, Cillario Jennifer, Robaglia-Schlupp Andr\u00e9e, Vincentelli Renaud, Cau Pierre, Szepetowski Pierre", "reference": { "type": "PubMed", "id": "18718938", "url": "https://pubmed.ncbi.nlm.nih.gov/18718938" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60687-1", "protein_name": "Sushi repeat-containing protein SRPX2", "gene_name": "SRPX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03405-1", "protein_name": "Urokinase plasminogen activator surface receptor", "gene_name": "PLAUR", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75173-1", "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 4", "gene_name": "ADAMTS4", "tax_name": 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9.", "journal": "Nature immunology", "date": "2008", "authors": "Park B, Brinkmann MM, Spooner E, Lee CC, Kim YM, Ploegh HL", "reference": { "type": "PubMed", "id": "18931679", "url": "https://pubmed.ncbi.nlm.nih.gov/18931679" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2011", "authors": "Kuznik A, Bencina M, Svajger U, Jeras M, Rozman B, Jerala R", "reference": { "type": "PubMed", "id": "21398612", "url": "https://pubmed.ncbi.nlm.nih.gov/21398612" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BT09-1", "protein_name": "Protein canopy homolog 3", "gene_name": "CNPY3", "tax_name": 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"Ewald SE, Engel A, Lee J, Wang M, Bogyo M, Barton GM", "reference": { "type": "PubMed", "id": "21402738", "url": "https://pubmed.ncbi.nlm.nih.gov/21402738" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58681-1", "protein_name": "Toll-like receptor 7", "gene_name": "Tlr7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P07711-1", "protein_name": "Procathepsin L", "gene_name": "CTSL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25774-1", "protein_name": "Cathepsin S", "gene_name": "CTSS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60911-1", "protein_name": "Cathepsin L2", "gene_name": "CTSV", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99538-1", "protein_name": "Legumain", "gene_name": "LGMN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", 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"species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21402738", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "IL-8 and cathepsin B as melanoma serum biomarkers.", "journal": "International journal of molecular sciences", "date": "2011", "authors": "Zhang H, Fu T, McGettigan S, Kumar S, Liu S, Speicher D, Schuchter L, Xu X", "reference": { "type": "PubMed", "id": "21673904", "url": "https://pubmed.ncbi.nlm.nih.gov/21673904" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10145-1", "protein_name": "Interleukin-8", "gene_name": "CXCL8", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "biomarkers": [ { "best_biomarker_role": [ "prognostic" ], 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Genet.", "date": "2017", "authors": "Ngcungcu Thandiswa, Oti Martin, Sitek Jan C, Haukanes Bj\u00f8rn I, Linghu Bolan, Bruccoleri Robert, Stokowy Tomasz, Oakeley Edward J, Yang Fan, Zhu Jiang, Sultan Marc, Schalkwijk Joost, van Vlijmen-Willems Ivonne M J J, von der Lippe Charlotte, Brunner Han G, Ersland Kari M, Grayson Wayne, Buechmann-Moller Stine, Sundnes Olav, Nirmala Nanguneri, Morgan Thomas M, van Bokhoven Hans, Steen Vidar M, Hull Peter R, Szustakowski Joseph, Staedtler Frank, Zhou Huiqing, Fiskerstrand Torunn, Ramsay Michele", "reference": { "type": "PubMed", "id": "28457472", "url": "https://pubmed.ncbi.nlm.nih.gov/28457472" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07858-1", "protein_name": "Cathepsin B", "gene_name": "CTSB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07858", "url": "https://www.uniprot.org/uniprotkb/P07858" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.28457472", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B.", "journal": "Proc. 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"authors": "Zhang Li, Jiao Kun, Liu Yun, Xu Guiqin, Yang Zhaojuan, Xiang Lvzhu, Chen Zehong, Xu Chen, Zuo You, Wu Zhibai, Zheng Ningqian, Zhang Xiaoren, Xia Qiang, Liu Yongzhong", "reference": { "type": "PubMed", "id": "38051955", "url": "https://pubmed.ncbi.nlm.nih.gov/38051955" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BZE9-1", "protein_name": "Tether containing UBX domain for GLUT4", "gene_name": "ASPSCR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BZE9", "url": "https://www.uniprot.org/uniprotkb/Q9BZE9" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38051955", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.", "journal": "Neuron", "date": "2007", "authors": "Xie Z, Moy LY, Sanada K, Zhou Y, Buchman JJ, Tsai LH", "reference": { "type": "PubMed", "id": "17920017", "url": "https://pubmed.ncbi.nlm.nih.gov/17920017" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": 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Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, Dorr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Volker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Volzke H, Blankenberg S", "reference": { "type": "PubMed", "id": "19584346", "url": "https://pubmed.ncbi.nlm.nih.gov/19584346" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8N960-1", "protein_name": "Centrosomal protein of 120 kDa", "gene_name": "CEP120", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T1Q4-1", "protein_name": "Solute carrier family 35 member F1", "gene_name": 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and CEP120 reveal roles in multisystem development.", "journal": "BMC developmental biology", "date": "2020", "authors": "Powell L, Barroso-Gil M, Clowry GJ, Devlin LA, Molinari E, Ramsbottom SA, Miles CG, Sayer JA", "reference": { "type": "PubMed", "id": "33297941", "url": "https://pubmed.ncbi.nlm.nih.gov/33297941" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8N960-1", "protein_name": "Centrosomal protein of 120 kDa", "gene_name": "CEP120", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8N960", "url": "https://www.uniprot.org/uniprotkb/Q8N960" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33297941", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": 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