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Biol. Chem.", "date": "2001", "authors": "Hassa\u00efne G, Courcoul M, Bessou G, Barthalay Y, Picard C, Olive D, Collette Y, Vigne R, Decroly E", "reference": { "type": "PubMed", "id": "11278465", "url": "https://pubmed.ncbi.nlm.nih.gov/11278465" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11278465", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Korkaya H, Jameel S, Gupta D, Tyagi S, Kumar R, Zafrullah M, Mazumdar M, Lal S K, Xiaofang L, Sehgal D, Das S R, Sahal D", "reference": { "type": "PubMed", "id": "11518702", "url": "https://pubmed.ncbi.nlm.nih.gov/11518702" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13769-1", "protein_name": "THO complex subunit 5", "gene_name": "THOC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 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"uniprot_canonical_ac": "P63000-1", "protein_name": "Ras-related C3 botulinum toxin substrate 1", "gene_name": "RAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92608-1", "protein_name": "Dedicator of cytokinesis protein 2", "gene_name": "DOCK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14737186", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Podar K, Mostoslavsky G, Sattler M, Tai YT, Hayashi T, Catley LP, Hideshima T, Mulligan RC, Chauhan D, Anderson KC", "reference": { "type": "PubMed", "id": "15010462", "url": "https://pubmed.ncbi.nlm.nih.gov/15010462" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13480-1", "protein_name": "GRB2-associated-binding protein 1", "gene_name": "GAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" } ], 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "The genomic locus of the human hemopoietic-specific cell protein tyrosine kinase (PTK)-encoding gene (HCK) confirms conservation of exon-intron structure among human PTKs of the src family.", "journal": "Gene", "date": "1992", "authors": "Hradetzky D, Strebhardt K, Rubsamen-Waigmann H", "reference": { "type": "PubMed", "id": "1572549", "url": "https://pubmed.ncbi.nlm.nih.gov/1572549" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1572549", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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Biol. Chem.", "date": "2006", "authors": "Trible Ronald P, Emert-Sedlak Lori, Smithgall Thomas E", "reference": { "type": "PubMed", "id": "16849330", "url": "https://pubmed.ncbi.nlm.nih.gov/16849330" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16849330", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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Med. Chem. Lett.", "date": "2006", "authors": "Sabat Mark, VanRens John C, Laufersweiler Matthew J, Brugel Todd A, Maier Jennifer, Golebiowski Adam, De Biswanath, Easwaran Vijayasurian, Hsieh Lily C, Walter Richard L, Mekel Marlene J, Evdokimov Artem, Janusz Michael J", "reference": { "type": "PubMed", "id": "16997556", "url": "https://pubmed.ncbi.nlm.nih.gov/16997556" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16997556", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Solution structure of a Hck SH3 domain ligand complex reveals novel interaction modes.", "journal": "J. Mol. 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of p73 by Hck through kinase-dependent and independent mechanisms.", "journal": "BMC molecular biology", "date": "2007", "authors": "Paliwal P, Radha V, Swarup G", "reference": { "type": "PubMed", "id": "17535448", "url": "https://pubmed.ncbi.nlm.nih.gov/17535448" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15350-1", "protein_name": "Tumor protein p73", "gene_name": "TP73", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46937-1", "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 28, "end_pos": 28, "kinase_uniprot_canonical_ac": "P08631-1", "kinase_gene_name": "HCK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O15350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O15350" }, { "database": "PubMed", "id": "17535448", "url": "https://pubmed.ncbi.nlm.nih.gov/17535448" } ], "site_lbl": "Tyr28", "uniprot_canonical_ac": "O15350-1" }, { "start_pos": 28, "end_pos": 28, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SRC and HCK", "evidence": [ { "database": "UniProtKB", "id": "O15350", "url": "https://www.uniprot.org/uniprotkb/O15350" }, { "database": "iPTMnet", "id": "O15350", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O15350" }, { "database": "PubMed", "id": "17535448", "url": 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2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Src family tyrosine kinases phosphorylate Flt3 on juxtamembrane tyrosines and interfere with receptor maturation in a kinase-dependent manner.", "journal": "Annals of hematology", "date": "2007", "authors": "Mitina O, Warmuth M, Krause G, Hallek M, Obermeier A", "reference": { "type": "PubMed", "id": "17668209", "url": "https://pubmed.ncbi.nlm.nih.gov/17668209" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49771-1", "protein_name": "Fms-related tyrosine kinase 3 ligand", "gene_name": "FLT3LG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06239-1", "protein_name": "Tyrosine-protein kinase Lck", "gene_name": "LCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36888-1", "protein_name": "Receptor-type tyrosine-protein kinase FLT3", "gene_name": "FLT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17668209", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "Q6ZMJ4-1", "protein_name": "Interleukin-34", "gene_name": "IL34", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60880-1", "protein_name": "Synaptosomal-associated protein 25", "gene_name": "SNAP25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18827-1", "protein_name": "Syndecan-1", "gene_name": "SDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13277-1", "protein_name": "Syntaxin-3", "gene_name": "STX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75791-1", "protein_name": "GRB2-related adapter protein 2", "gene_name": "GRAP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23471-1", "protein_name": "Receptor-type tyrosine-protein phosphatase zeta", "gene_name": "PTPRZ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWW8-1", "protein_name": "GRB2-associated-binding protein 3", "gene_name": "GAB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42574-1", "protein_name": "Caspase-3", "gene_name": "CASP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40222-1", "protein_name": "Alpha-taxilin", "gene_name": "TXLNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15357-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2", "gene_name": "INPPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16885-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "PLCG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09919-1", "protein_name": "Granulocyte colony-stimulating factor", "gene_name": "CSF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08334-1", "protein_name": "Interleukin-10 receptor subunit beta", "gene_name": "IL10RB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01116-1", "protein_name": "GTPase KRas", "gene_name": "KRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IU57-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IU54-1", "protein_name": "Interferon lambda-1", "gene_name": "IFNL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13769-1", "protein_name": "THO complex subunit 5", "gene_name": "THOC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15833-1", "protein_name": "Syntaxin-binding protein 2", "gene_name": "STXBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12846-1", "protein_name": "Syntaxin-4", "gene_name": "STX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16623-1", "protein_name": "Syntaxin-1A", "gene_name": "STX1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01730-1", "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14005-1", "protein_name": "Pro-interleukin-16", "gene_name": "IL16", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23458-1", "protein_name": "Tyrosine-protein kinase JAK1", "gene_name": "JAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8R1R4-1", "protein_name": "Interleukin-34", "gene_name": "Il34", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": 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J. 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Biol. 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly.", "journal": "Traffic", "date": "2011", "authors": "Horenkamp Florian A, Breuer Sebastian, Schulte Antje, L\u00fclf Sebastian, Weyand Michael, Saksela Kalle, Geyer Matthias", "reference": { "type": "PubMed", "id": "21477083", "url": "https://pubmed.ncbi.nlm.nih.gov/21477083" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21477083", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": 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[] } ] }, { "title": "CSF-1 receptor signaling in myeloid cells.", "journal": "Cold Spring Harbor perspectives in biology", "date": "2014", "authors": "Stanley ER, Chitu V", "reference": { "type": "PubMed", "id": "24890514", "url": "https://pubmed.ncbi.nlm.nih.gov/24890514" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92835-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "gene_name": "INPP5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07333-1", "protein_name": "Macrophage colony-stimulating factor 1 receptor", "gene_name": "CSF1R", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09603-1", 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Biol.", "date": "1987", "authors": "Ziegler S F, Marth J D, Lewis D B, Perlmutter R M", "reference": { "type": "PubMed", "id": "3453117", "url": "https://pubmed.ncbi.nlm.nih.gov/3453117" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.3453117", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 23, "end_pos": 23, "sequence_org": "G", "sequence_mut": "A", "comment": "Myristoylation and palmitoylation are abolished, leading to entirely cytoplasmic localization; in isoform 2.", "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" }, { "database": "PubMed", "id": "7791757", "url": "https://pubmed.ncbi.nlm.nih.gov/7791757" } ], "uniprot_canonical_ac": "P08631-1" }, { "start_pos": 24, "end_pos": 24, "sequence_org": "C", "sequence_mut": "S", "comment": "Palmitoylation is abolished, some cytoplasmic and no calveolar localization; in isoform 2.", "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" }, { "database": "PubMed", "id": "7791757", "url": "https://pubmed.ncbi.nlm.nih.gov/7791757" } ], "uniprot_canonical_ac": "P08631-1" }, { "start_pos": 3, "end_pos": 3, 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells.", "journal": "The Journal of biological chemistry", "date": "1994", "authors": "Ghazizadeh S, Bolen JB, Fleit HB", "reference": { "type": "PubMed", "id": "8132624", "url": "https://pubmed.ncbi.nlm.nih.gov/8132624" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12318-1", "protein_name": "Low affinity immunoglobulin gamma Fc region receptor II-a", "gene_name": "FCGR2A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"Human" }, { "uniprot_canonical_ac": "Q13769-1", "protein_name": "THO complex subunit 5", "gene_name": "THOC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQC2-1", "protein_name": "GRB2-associated-binding protein 2", "gene_name": "GAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P08631", "url": "https://www.uniprot.org/uniprotkb/P08631" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8355686", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": 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Biol. 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Biol. 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Chem.", "date": "2000", "authors": "Cheng A, Kaldis P, Solomon M J", "reference": { "type": "PubMed", "id": "10934208", "url": "https://pubmed.ncbi.nlm.nih.gov/10934208" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75688-1", "protein_name": "Protein phosphatase 1B", "gene_name": "PPM1B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75688", "url": "https://www.uniprot.org/uniprotkb/O75688" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10934208", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural genomics of protein phosphatases.", "journal": "J. Struct. Funct. Genomics", "date": "2007", "authors": "Almo SC, Bonanno JB, Sauder JM, Emtage S, Dilorenzo TP, Malashkevich V, Wasserman SR, Swaminathan S, Eswaramoorthy S, Agarwal R, Kumaran D, Madegowda M, Ragumani S, Patskovsky Y, Alvarado J, Ramagopal UA, Faber-Barata J, Chance MR, Sali A, Fiser A, Zhang ZY, Lawrence DS, Burley SK", "reference": { "type": "PubMed", "id": "18058037", "url": "https://pubmed.ncbi.nlm.nih.gov/18058037" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75688-1", "protein_name": "Protein phosphatase 1B", "gene_name": "PPM1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15194-1", "protein_name": "CTD small phosphatase-like protein", "gene_name": "CTDSPL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD0-1", "protein_name": "Chronophin", "gene_name": "PDXP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q64605-1", "protein_name": "Receptor-type tyrosine-protein phosphatase S", "gene_name": "Ptprs", "tax_name": "Rat" }, { "uniprot_canonical_ac": "O14595-1", "protein_name": "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2", "gene_name": "CTDSP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8BTR5-1", "protein_name": "Dual specificity phosphatase 28", "gene_name": "Dusp28", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3J5-1", "protein_name": "Protein phosphatase Mn(2+)-dependent 1K", "gene_name": "PPM1K", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9D358-1", "protein_name": "Low molecular weight phosphotyrosine protein phosphatase", "gene_name": "Acp1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q13332-1", "protein_name": "Receptor-type tyrosine-protein phosphatase S", "gene_name": "PTPRS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUJ0-1", "protein_name": "Serine/threonine/tyrosine-interacting protein", "gene_name": "STYX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99956-1", "protein_name": "Dual specificity protein phosphatase 9", "gene_name": "DUSP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16849-1", "protein_name": "Receptor-type tyrosine-protein phosphatase-like N", "gene_name": "PTPRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16827-1", "protein_name": "Receptor-type tyrosine-protein phosphatase O", "gene_name": "PTPRO", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75688", "url": "https://www.uniprot.org/uniprotkb/O75688" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18058037", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ 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